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Network neighborhood for query Sequence : ATL2_MOUSE

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ATL2_MOUSE
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ATL2_HUMAN
θ value	0 (rank : 1)	NC score	0.997938 (rank : 2)
Query Neighborhood Hits	137	Target Neighborhood Hits	125	Shared Neighborhood Hits	111
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	137	Target Neighborhood Hits	137	Shared Neighborhood Hits	137
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATS9_HUMAN
θ value	3.2585e-50 (rank : 3)	NC score	0.867094 (rank : 11)
Query Neighborhood Hits	137	Target Neighborhood Hits	219	Shared Neighborhood Hits	98
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS6_HUMAN
θ value	9.48078e-50 (rank : 4)	NC score	0.853063 (rank : 28)
Query Neighborhood Hits	137	Target Neighborhood Hits	141	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS16_HUMAN
θ value	2.1121e-49 (rank : 5)	NC score	0.862159 (rank : 19)
Query Neighborhood Hits	137	Target Neighborhood Hits	208	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS18_MOUSE
θ value	1.36902e-48 (rank : 6)	NC score	0.875146 (rank : 8)
Query Neighborhood Hits	137	Target Neighborhood Hits	163	Shared Neighborhood Hits	88
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS12_HUMAN
θ value	1.15895e-47 (rank : 7)	NC score	0.859896 (rank : 22)
Query Neighborhood Hits	137	Target Neighborhood Hits	251	Shared Neighborhood Hits	87
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS18_HUMAN
θ value	1.15895e-47 (rank : 8)	NC score	0.867779 (rank : 9)
Query Neighborhood Hits	137	Target Neighborhood Hits	169	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS16_MOUSE
θ value	1.51363e-47 (rank : 9)	NC score	0.863545 (rank : 17)
Query Neighborhood Hits	137	Target Neighborhood Hits	179	Shared Neighborhood Hits	89
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS12_MOUSE
θ value	3.37202e-47 (rank : 10)	NC score	0.860185 (rank : 21)
Query Neighborhood Hits	137	Target Neighborhood Hits	220	Shared Neighborhood Hits	87
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS20_MOUSE
θ value	2.04573e-44 (rank : 11)	NC score	0.858891 (rank : 23)
Query Neighborhood Hits	137	Target Neighborhood Hits	225	Shared Neighborhood Hits	94
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS19_MOUSE
θ value	5.95217e-44 (rank : 12)	NC score	0.867209 (rank : 10)
Query Neighborhood Hits	137	Target Neighborhood Hits	188	Shared Neighborhood Hits	86
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS20_HUMAN
θ value	5.95217e-44 (rank : 13)	NC score	0.850417 (rank : 31)
Query Neighborhood Hits	137	Target Neighborhood Hits	192	Shared Neighborhood Hits	92
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS7_HUMAN
θ value	1.32601e-43 (rank : 14)	NC score	0.844200 (rank : 32)
Query Neighborhood Hits	137	Target Neighborhood Hits	169	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS19_HUMAN
θ value	1.91475e-42 (rank : 15)	NC score	0.864595 (rank : 13)
Query Neighborhood Hits	137	Target Neighborhood Hits	203	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATL5_HUMAN
θ value	8.04462e-41 (rank : 16)	NC score	0.927083 (rank : 3)
Query Neighborhood Hits	137	Target Neighborhood Hits	103	Shared Neighborhood Hits	74
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATS8_HUMAN
θ value	2.34062e-40 (rank : 17)	NC score	0.862144 (rank : 20)
Query Neighborhood Hits	137	Target Neighborhood Hits	145	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS14_HUMAN
θ value	1.51715e-39 (rank : 18)	NC score	0.850984 (rank : 30)
Query Neighborhood Hits	137	Target Neighborhood Hits	382	Shared Neighborhood Hits	87
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS8_MOUSE
θ value	1.98146e-39 (rank : 19)	NC score	0.864453 (rank : 14)
Query Neighborhood Hits	137	Target Neighborhood Hits	139	Shared Neighborhood Hits	77
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS3_HUMAN
θ value	1.6774e-38 (rank : 20)	NC score	0.856655 (rank : 26)
Query Neighborhood Hits	137	Target Neighborhood Hits	179	Shared Neighborhood Hits	87
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS2_HUMAN
θ value	8.32485e-38 (rank : 21)	NC score	0.866669 (rank : 12)
Query Neighborhood Hits	137	Target Neighborhood Hits	179	Shared Neighborhood Hits	83
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS5_HUMAN
θ value	2.42216e-37 (rank : 22)	NC score	0.841287 (rank : 33)
Query Neighborhood Hits	137	Target Neighborhood Hits	141	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS5_MOUSE
θ value	3.16345e-37 (rank : 23)	NC score	0.839426 (rank : 34)
Query Neighborhood Hits	137	Target Neighborhood Hits	147	Shared Neighborhood Hits	77
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS2_MOUSE
θ value	3.86705e-35 (rank : 24)	NC score	0.863943 (rank : 16)
Query Neighborhood Hits	137	Target Neighborhood Hits	179	Shared Neighborhood Hits	82
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS15_HUMAN
θ value	1.12514e-34 (rank : 25)	NC score	0.858245 (rank : 25)
Query Neighborhood Hits	137	Target Neighborhood Hits	151	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATL3_HUMAN
θ value	5.584e-34 (rank : 26)	NC score	0.775538 (rank : 35)
Query Neighborhood Hits	137	Target Neighborhood Hits	414	Shared Neighborhood Hits	90
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATS1_HUMAN
θ value	9.52487e-34 (rank : 27)	NC score	0.854516 (rank : 27)
Query Neighborhood Hits	137	Target Neighborhood Hits	159	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS1_MOUSE
θ value	9.52487e-34 (rank : 28)	NC score	0.853040 (rank : 29)
Query Neighborhood Hits	137	Target Neighborhood Hits	158	Shared Neighborhood Hits	88
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS17_HUMAN
θ value	2.34606e-32 (rank : 29)	NC score	0.858886 (rank : 24)
Query Neighborhood Hits	137	Target Neighborhood Hits	194	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS4_HUMAN
θ value	1.52067e-31 (rank : 30)	NC score	0.864208 (rank : 15)
Query Neighborhood Hits	137	Target Neighborhood Hits	138	Shared Neighborhood Hits	75
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS4_MOUSE
θ value	1.52067e-31 (rank : 31)	NC score	0.862881 (rank : 18)
Query Neighborhood Hits	137	Target Neighborhood Hits	145	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATL1_MOUSE
θ value	4.42448e-31 (rank : 32)	NC score	0.903853 (rank : 5)
Query Neighborhood Hits	137	Target Neighborhood Hits	80	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATL1_HUMAN
θ value	1.6813e-30 (rank : 33)	NC score	0.905776 (rank : 4)
Query Neighborhood Hits	137	Target Neighborhood Hits	93	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

CI094_HUMAN
θ value	7.06379e-29 (rank : 34)	NC score	0.626129 (rank : 40)
Query Neighborhood Hits	137	Target Neighborhood Hits	310	Shared Neighborhood Hits	75
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

ATS13_HUMAN
θ value	1.57365e-28 (rank : 35)	NC score	0.876848 (rank : 6)
Query Neighborhood Hits	137	Target Neighborhood Hits	238	Shared Neighborhood Hits	83
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_MOUSE
θ value	1.73987e-27 (rank : 36)	NC score	0.875688 (rank : 7)
Query Neighborhood Hits	137	Target Neighborhood Hits	227	Shared Neighborhood Hits	87
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

BAI1_MOUSE
θ value	3.07829e-16 (rank : 37)	NC score	0.530691 (rank : 43)
Query Neighborhood Hits	137	Target Neighborhood Hits	340	Shared Neighborhood Hits	84
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_HUMAN
θ value	8.95645e-16 (rank : 38)	NC score	0.528141 (rank : 45)
Query Neighborhood Hits	137	Target Neighborhood Hits	375	Shared Neighborhood Hits	86
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

TSP1_HUMAN
θ value	8.95645e-16 (rank : 39)	NC score	0.519532 (rank : 48)
Query Neighborhood Hits	137	Target Neighborhood Hits	389	Shared Neighborhood Hits	102
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	2.60593e-15 (rank : 40)	NC score	0.518850 (rank : 49)
Query Neighborhood Hits	137	Target Neighborhood Hits	396	Shared Neighborhood Hits	102
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

HMCN1_HUMAN
θ value	3.40345e-15 (rank : 41)	NC score	0.313505 (rank : 74)
Query Neighborhood Hits	137	Target Neighborhood Hits	983	Shared Neighborhood Hits	101
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

SPON1_HUMAN
θ value	3.40345e-15 (rank : 42)	NC score	0.668456 (rank : 38)
Query Neighborhood Hits	137	Target Neighborhood Hits	117	Shared Neighborhood Hits	84
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
θ value	9.90251e-15 (rank : 43)	NC score	0.665398 (rank : 39)
Query Neighborhood Hits	137	Target Neighborhood Hits	123	Shared Neighborhood Hits	86
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

BAI2_MOUSE
θ value	1.29331e-14 (rank : 44)	NC score	0.529342 (rank : 44)
Query Neighborhood Hits	137	Target Neighborhood Hits	323	Shared Neighborhood Hits	84
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_HUMAN
θ value	2.20605e-14 (rank : 45)	NC score	0.531213 (rank : 42)
Query Neighborhood Hits	137	Target Neighborhood Hits	332	Shared Neighborhood Hits	85
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

SEM5A_HUMAN
θ value	4.91457e-14 (rank : 46)	NC score	0.470691 (rank : 53)
Query Neighborhood Hits	137	Target Neighborhood Hits	177	Shared Neighborhood Hits	83
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5A_MOUSE
θ value	2.0648e-12 (rank : 47)	NC score	0.460086 (rank : 55)
Query Neighborhood Hits	137	Target Neighborhood Hits	162	Shared Neighborhood Hits	83
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

PROP_HUMAN
θ value	3.52202e-12 (rank : 48)	NC score	0.695190 (rank : 36)
Query Neighborhood Hits	137	Target Neighborhood Hits	126	Shared Neighborhood Hits	78
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

BAI3_HUMAN
θ value	1.02475e-11 (rank : 49)	NC score	0.521688 (rank : 46)
Query Neighborhood Hits	137	Target Neighborhood Hits	246	Shared Neighborhood Hits	80
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	1.33837e-11 (rank : 50)	NC score	0.521293 (rank : 47)
Query Neighborhood Hits	137	Target Neighborhood Hits	250	Shared Neighborhood Hits	85
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

TSP2_MOUSE
θ value	1.33837e-11 (rank : 51)	NC score	0.511406 (rank : 51)
Query Neighborhood Hits	137	Target Neighborhood Hits	352	Shared Neighborhood Hits	99
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

PROP_MOUSE
θ value	5.62301e-10 (rank : 52)	NC score	0.688126 (rank : 37)
Query Neighborhood Hits	137	Target Neighborhood Hits	165	Shared Neighborhood Hits	83
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

TSP2_HUMAN
θ value	5.62301e-10 (rank : 53)	NC score	0.506447 (rank : 52)
Query Neighborhood Hits	137	Target Neighborhood Hits	359	Shared Neighborhood Hits	99
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

SSPO_MOUSE
θ value	9.59137e-10 (rank : 54)	NC score	0.442323 (rank : 60)
Query Neighborhood Hits	137	Target Neighborhood Hits	800	Shared Neighborhood Hits	111
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

SEM5B_MOUSE
θ value	5.81887e-07 (rank : 55)	NC score	0.450714 (rank : 58)
Query Neighborhood Hits	137	Target Neighborhood Hits	190	Shared Neighborhood Hits	85
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM5B_HUMAN
θ value	1.29631e-06 (rank : 56)	NC score	0.447994 (rank : 59)
Query Neighborhood Hits	137	Target Neighborhood Hits	178	Shared Neighborhood Hits	85
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

THSD1_HUMAN
θ value	0.000121331 (rank : 57)	NC score	0.549218 (rank : 41)
Query Neighborhood Hits	137	Target Neighborhood Hits	136	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

CILP2_HUMAN
θ value	0.00020696 (rank : 58)	NC score	0.425413 (rank : 65)
Query Neighborhood Hits	137	Target Neighborhood Hits	307	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

UNC5A_MOUSE
θ value	0.000602161 (rank : 59)	NC score	0.467870 (rank : 54)
Query Neighborhood Hits	137	Target Neighborhood Hits	203	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5C_HUMAN
θ value	0.00102713 (rank : 60)	NC score	0.440679 (rank : 62)
Query Neighborhood Hits	137	Target Neighborhood Hits	226	Shared Neighborhood Hits	72
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	0.00102713 (rank : 61)	NC score	0.440915 (rank : 61)
Query Neighborhood Hits	137	Target Neighborhood Hits	225	Shared Neighborhood Hits	72
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

ADA10_HUMAN
θ value	0.00175202 (rank : 62)	NC score	0.164992 (rank : 111)
Query Neighborhood Hits	137	Target Neighborhood Hits	189	Shared Neighborhood Hits	41
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

UNC5D_HUMAN
θ value	0.00228821 (rank : 63)	NC score	0.432077 (rank : 63)
Query Neighborhood Hits	137	Target Neighborhood Hits	267	Shared Neighborhood Hits	72
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	0.00228821 (rank : 64)	NC score	0.428657 (rank : 64)
Query Neighborhood Hits	137	Target Neighborhood Hits	268	Shared Neighborhood Hits	72
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

ADA10_MOUSE
θ value	0.00298849 (rank : 65)	NC score	0.164059 (rank : 112)
Query Neighborhood Hits	137	Target Neighborhood Hits	194	Shared Neighborhood Hits	41
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

THSD1_MOUSE
θ value	0.00298849 (rank : 66)	NC score	0.512458 (rank : 50)
Query Neighborhood Hits	137	Target Neighborhood Hits	153	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

CILP1_MOUSE
θ value	0.0148317 (rank : 67)	NC score	0.319728 (rank : 72)
Query Neighborhood Hits	137	Target Neighborhood Hits	282	Shared Neighborhood Hits	77
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

UNC5B_MOUSE
θ value	0.0148317 (rank : 68)	NC score	0.453912 (rank : 56)
Query Neighborhood Hits	137	Target Neighborhood Hits	226	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5B_HUMAN
θ value	0.0193708 (rank : 69)	NC score	0.451377 (rank : 57)
Query Neighborhood Hits	137	Target Neighborhood Hits	225	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

NOV_MOUSE
θ value	0.0252991 (rank : 70)	NC score	0.159579 (rank : 113)
Query Neighborhood Hits	137	Target Neighborhood Hits	130	Shared Neighborhood Hits	57
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NOV_HUMAN
θ value	0.0563607 (rank : 71)	NC score	0.146463 (rank : 116)
Query Neighborhood Hits	137	Target Neighborhood Hits	128	Shared Neighborhood Hits	52
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

SREC2_HUMAN
θ value	0.0736092 (rank : 72)	NC score	0.044217 (rank : 178)
Query Neighborhood Hits	137	Target Neighborhood Hits	645	Shared Neighborhood Hits	38
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

WISP1_MOUSE
θ value	0.0736092 (rank : 73)	NC score	0.180499 (rank : 104)
Query Neighborhood Hits	137	Target Neighborhood Hits	123	Shared Neighborhood Hits	60
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

KRA92_HUMAN
θ value	0.0961366 (rank : 74)	NC score	0.085357 (rank : 136)
Query Neighborhood Hits	137	Target Neighborhood Hits	198	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

WISP1_HUMAN
θ value	0.0961366 (rank : 75)	NC score	0.173338 (rank : 110)
Query Neighborhood Hits	137	Target Neighborhood Hits	121	Shared Neighborhood Hits	60
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

SREC2_MOUSE
θ value	0.125558 (rank : 76)	NC score	0.046112 (rank : 176)
Query Neighborhood Hits	137	Target Neighborhood Hits	605	Shared Neighborhood Hits	44
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

ADA19_MOUSE
θ value	0.163984 (rank : 77)	NC score	0.276991 (rank : 78)
Query Neighborhood Hits	137	Target Neighborhood Hits	315	Shared Neighborhood Hits	52
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

CILP1_HUMAN
θ value	0.279714 (rank : 78)	NC score	0.314792 (rank : 73)
Query Neighborhood Hits	137	Target Neighborhood Hits	266	Shared Neighborhood Hits	74
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

LAMC1_MOUSE
θ value	0.279714 (rank : 79)	NC score	0.025650 (rank : 190)
Query Neighborhood Hits	137	Target Neighborhood Hits	856	Shared Neighborhood Hits	30
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

CO6_HUMAN
θ value	0.62314 (rank : 80)	NC score	0.382099 (rank : 66)
Query Neighborhood Hits	137	Target Neighborhood Hits	331	Shared Neighborhood Hits	82
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CTGF_MOUSE
θ value	0.62314 (rank : 81)	NC score	0.127679 (rank : 125)
Query Neighborhood Hits	137	Target Neighborhood Hits	124	Shared Neighborhood Hits	53
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

FRAS1_MOUSE
θ value	0.62314 (rank : 82)	NC score	0.102072 (rank : 131)
Query Neighborhood Hits	137	Target Neighborhood Hits	747	Shared Neighborhood Hits	82
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMC1_HUMAN
θ value	0.62314 (rank : 83)	NC score	0.022833 (rank : 191)
Query Neighborhood Hits	137	Target Neighborhood Hits	922	Shared Neighborhood Hits	33
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

NOTC3_HUMAN
θ value	0.62314 (rank : 84)	NC score	0.038951 (rank : 182)
Query Neighborhood Hits	137	Target Neighborhood Hits	1062	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PCLO_HUMAN
θ value	0.62314 (rank : 85)	NC score	0.010099 (rank : 201)
Query Neighborhood Hits	137	Target Neighborhood Hits	2046	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CYR61_MOUSE
θ value	0.813845 (rank : 86)	NC score	0.137109 (rank : 123)
Query Neighborhood Hits	137	Target Neighborhood Hits	156	Shared Neighborhood Hits	61
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

N4BP2_HUMAN
θ value	1.06291 (rank : 87)	NC score	0.020691 (rank : 195)
Query Neighborhood Hits	137	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

NOTC4_HUMAN
θ value	1.06291 (rank : 88)	NC score	0.031297 (rank : 187)
Query Neighborhood Hits	137	Target Neighborhood Hits	905	Shared Neighborhood Hits	49
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

WISP3_HUMAN
θ value	1.06291 (rank : 89)	NC score	0.146255 (rank : 118)
Query Neighborhood Hits	137	Target Neighborhood Hits	87	Shared Neighborhood Hits	45
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

CYR61_HUMAN
θ value	1.38821 (rank : 90)	NC score	0.151523 (rank : 114)
Query Neighborhood Hits	137	Target Neighborhood Hits	159	Shared Neighborhood Hits	66
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

FBLN5_MOUSE
θ value	1.38821 (rank : 91)	NC score	0.031702 (rank : 186)
Query Neighborhood Hits	137	Target Neighborhood Hits	317	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FRAS1_HUMAN
θ value	1.38821 (rank : 92)	NC score	0.084278 (rank : 137)
Query Neighborhood Hits	137	Target Neighborhood Hits	759	Shared Neighborhood Hits	73
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

PASK_MOUSE
θ value	1.38821 (rank : 93)	NC score	-0.002261 (rank : 216)
Query Neighborhood Hits	137	Target Neighborhood Hits	867	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CEE6, Q91YD8	Gene names	Pask, Kiaa0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN).

PCLO_MOUSE
θ value	1.38821 (rank : 94)	NC score	0.009993 (rank : 202)
Query Neighborhood Hits	137	Target Neighborhood Hits	2275	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ATX2L_HUMAN
θ value	1.81305 (rank : 95)	NC score	0.014296 (rank : 197)
Query Neighborhood Hits	137	Target Neighborhood Hits	443	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

CTGF_HUMAN
θ value	1.81305 (rank : 96)	NC score	0.122517 (rank : 127)
Query Neighborhood Hits	137	Target Neighborhood Hits	128	Shared Neighborhood Hits	53
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

LRP1B_HUMAN
θ value	1.81305 (rank : 97)	NC score	0.034336 (rank : 184)
Query Neighborhood Hits	137	Target Neighborhood Hits	602	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MEGF6_HUMAN
θ value	1.81305 (rank : 98)	NC score	0.045747 (rank : 177)
Query Neighborhood Hits	137	Target Neighborhood Hits	671	Shared Neighborhood Hits	62
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

ZIC3_HUMAN
θ value	2.36792 (rank : 99)	NC score	-0.003121 (rank : 218)
Query Neighborhood Hits	137	Target Neighborhood Hits	714	Shared Neighborhood Hits	5
SwissProt Accessions	O60481	Gene names	ZIC3
Domain Architecture
Description	Zinc finger protein ZIC 3 (Zinc finger protein of the cerebellum 3).

ZIC3_MOUSE
θ value	2.36792 (rank : 100)	NC score	-0.003115 (rank : 217)
Query Neighborhood Hits	137	Target Neighborhood Hits	713	Shared Neighborhood Hits	5
SwissProt Accessions	Q62521	Gene names	Zic3
Domain Architecture
Description	Zinc finger protein ZIC 3 (Zinc finger protein of the cerebellum 3).

BRWD1_HUMAN
θ value	3.0926 (rank : 101)	NC score	0.000775 (rank : 210)
Query Neighborhood Hits	137	Target Neighborhood Hits	448	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

TENX_HUMAN
θ value	3.0926 (rank : 102)	NC score	0.042742 (rank : 179)
Query Neighborhood Hits	137	Target Neighborhood Hits	789	Shared Neighborhood Hits	53
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

UNC5A_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.349868 (rank : 69)
Query Neighborhood Hits	137	Target Neighborhood Hits	198	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

ATX2L_MOUSE
θ value	4.03905 (rank : 104)	NC score	0.011845 (rank : 199)
Query Neighborhood Hits	137	Target Neighborhood Hits	401	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

EZH2_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.011752 (rank : 200)
Query Neighborhood Hits	137	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
θ value	4.03905 (rank : 106)	NC score	0.013251 (rank : 198)
Query Neighborhood Hits	137	Target Neighborhood Hits	86	Shared Neighborhood Hits	10
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

KR106_HUMAN
θ value	4.03905 (rank : 107)	NC score	0.076260 (rank : 139)
Query Neighborhood Hits	137	Target Neighborhood Hits	347	Shared Neighborhood Hits	46
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

TRBM_MOUSE
θ value	4.03905 (rank : 108)	NC score	0.039665 (rank : 181)
Query Neighborhood Hits	137	Target Neighborhood Hits	361	Shared Neighborhood Hits	31
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

WISP2_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.180297 (rank : 107)
Query Neighborhood Hits	137	Target Neighborhood Hits	126	Shared Neighborhood Hits	63
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

CO7_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.323323 (rank : 71)
Query Neighborhood Hits	137	Target Neighborhood Hits	278	Shared Neighborhood Hits	72
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

JPH2_MOUSE
θ value	5.27518 (rank : 111)	NC score	0.003848 (rank : 204)
Query Neighborhood Hits	137	Target Neighborhood Hits	279	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

TNR4_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.021042 (rank : 194)
Query Neighborhood Hits	137	Target Neighborhood Hits	152	Shared Neighborhood Hits	18
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

UBP47_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.003339 (rank : 206)
Query Neighborhood Hits	137	Target Neighborhood Hits	149	Shared Neighborhood Hits	4
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

WISP2_MOUSE
θ value	5.27518 (rank : 114)	NC score	0.180369 (rank : 106)
Query Neighborhood Hits	137	Target Neighborhood Hits	129	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

ANX10_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.006294 (rank : 203)
Query Neighborhood Hits	137	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZ10	Gene names	Anxa10
Domain Architecture
Description	Annexin A10.

ERBB3_MOUSE
θ value	6.88961 (rank : 116)	NC score	-0.001559 (rank : 214)
Query Neighborhood Hits	137	Target Neighborhood Hits	898	Shared Neighborhood Hits	16
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

FBLN3_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.028552 (rank : 189)
Query Neighborhood Hits	137	Target Neighborhood Hits	279	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

KRA32_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.021044 (rank : 193)
Query Neighborhood Hits	137	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYR7	Gene names	KRTAP3-2, KAP3.2, KRTAP3.2
Domain Architecture
Description	Keratin-associated protein 3-2 (Keratin-associated protein 3.2) (High sulfur keratin-associated protein 3.2).

KRA33_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.021603 (rank : 192)
Query Neighborhood Hits	137	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYR6, Q52LP0	Gene names	KRTAP3-3, KAP3.3, KRTAP3.3
Domain Architecture
Description	Keratin-associated protein 3-3 (Keratin-associated protein 3.3) (High sulfur keratin-associated protein 3.3).

M3K6_HUMAN
θ value	6.88961 (rank : 120)	NC score	-0.006103 (rank : 221)
Query Neighborhood Hits	137	Target Neighborhood Hits	889	Shared Neighborhood Hits	5
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

TPR_HUMAN
θ value	6.88961 (rank : 121)	NC score	-0.006023 (rank : 220)
Query Neighborhood Hits	137	Target Neighborhood Hits	1921	Shared Neighborhood Hits	7
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

WNT4_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.000868 (rank : 209)
Query Neighborhood Hits	137	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	P56705, Q5TZQ0, Q96T81, Q9BXF5, Q9H1J8, Q9UJM2	Gene names	WNT4
Domain Architecture
Description	Protein Wnt-4 precursor.

ZN473_MOUSE
θ value	6.88961 (rank : 123)	NC score	-0.005729 (rank : 219)
Query Neighborhood Hits	137	Target Neighborhood Hits	824	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BI67, Q8BI98, Q8BIB7	Gene names	Znf473, Zfp100, Zfp473
Domain Architecture	No domain graphic available
Description	Zinc finger protein 473 homolog (Zinc finger protein 100) (Zfp-100).

CORT_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.037131 (rank : 183)
Query Neighborhood Hits	137	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	P56469, Q9R1P8	Gene names	Cort
Domain Architecture
Description	Cortistatin precursor [Contains: Cortistatin-14].

CSKI1_HUMAN
θ value	8.99809 (rank : 125)	NC score	-0.001172 (rank : 213)
Query Neighborhood Hits	137	Target Neighborhood Hits	997	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

FBLN5_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.032399 (rank : 185)
Query Neighborhood Hits	137	Target Neighborhood Hits	329	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

KLH13_HUMAN
θ value	8.99809 (rank : 127)	NC score	-0.000472 (rank : 211)
Query Neighborhood Hits	137	Target Neighborhood Hits	193	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2N7, Q6P2E3, Q96QI7, Q9UDN9	Gene names	KLHL13, BKLHD2, KIAA1309
Domain Architecture
Description	Kelch-like protein 13 (BTB and kelch domain-containing protein 2).

KLHL9_MOUSE
θ value	8.99809 (rank : 128)	NC score	-0.000512 (rank : 212)
Query Neighborhood Hits	137	Target Neighborhood Hits	195	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPT1	Gene names	Klhl9, Kiaa1354
Domain Architecture	No domain graphic available
Description	Kelch-like protein 9.

KR122_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.016260 (rank : 196)
Query Neighborhood Hits	137	Target Neighborhood Hits	97	Shared Neighborhood Hits	13
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

KRA98_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.072192 (rank : 144)
Query Neighborhood Hits	137	Target Neighborhood Hits	185	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

LRP8_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.031188 (rank : 188)
Query Neighborhood Hits	137	Target Neighborhood Hits	385	Shared Neighborhood Hits	31
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

M3K12_MOUSE
θ value	8.99809 (rank : 132)	NC score	-0.006652 (rank : 222)
Query Neighborhood Hits	137	Target Neighborhood Hits	957	Shared Neighborhood Hits	6
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

MILK1_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.001805 (rank : 207)
Query Neighborhood Hits	137	Target Neighborhood Hits	788	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NFX1_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.042254 (rank : 180)
Query Neighborhood Hits	137	Target Neighborhood Hits	405	Shared Neighborhood Hits	31
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

OXRP_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.001222 (rank : 208)
Query Neighborhood Hits	137	Target Neighborhood Hits	544	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PTN13_HUMAN
θ value	8.99809 (rank : 136)	NC score	-0.002131 (rank : 215)
Query Neighborhood Hits	137	Target Neighborhood Hits	471	Shared Neighborhood Hits	4
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

VMDL3_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.003441 (rank : 205)
Query Neighborhood Hits	137	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q6H1V1	Gene names	Vmd2l3
Domain Architecture	No domain graphic available
Description	Bestrophin-4 (Vitelliform macular dystrophy 2-like protein 3).

AD26A_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.179008 (rank : 108)
Query Neighborhood Hits	137	Target Neighborhood Hits	165	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA11_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.151513 (rank : 115)
Query Neighborhood Hits	137	Target Neighborhood Hits	259	Shared Neighborhood Hits	43
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.174206 (rank : 109)
Query Neighborhood Hits	137	Target Neighborhood Hits	263	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA12_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.249129 (rank : 84)
Query Neighborhood Hits	137	Target Neighborhood Hits	224	Shared Neighborhood Hits	45
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA12_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.244187 (rank : 85)
Query Neighborhood Hits	137	Target Neighborhood Hits	474	Shared Neighborhood Hits	50
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA15_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.231865 (rank : 89)
Query Neighborhood Hits	137	Target Neighborhood Hits	288	Shared Neighborhood Hits	47
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA15_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.205810 (rank : 92)
Query Neighborhood Hits	137	Target Neighborhood Hits	324	Shared Neighborhood Hits	54
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA17_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.136000 (rank : 124)
Query Neighborhood Hits	137	Target Neighborhood Hits	223	Shared Neighborhood Hits	46
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA17_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.145614 (rank : 119)
Query Neighborhood Hits	137	Target Neighborhood Hits	201	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA18_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.104348 (rank : 130)
Query Neighborhood Hits	137	Target Neighborhood Hits	184	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA18_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.127484 (rank : 126)
Query Neighborhood Hits	137	Target Neighborhood Hits	227	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA19_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.261541 (rank : 80)
Query Neighborhood Hits	137	Target Neighborhood Hits	381	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA20_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.140194 (rank : 121)
Query Neighborhood Hits	137	Target Neighborhood Hits	143	Shared Neighborhood Hits	40
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA21_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.180397 (rank : 105)
Query Neighborhood Hits	137	Target Neighborhood Hits	181	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA21_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.194776 (rank : 96)
Query Neighborhood Hits	137	Target Neighborhood Hits	172	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA22_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.200855 (rank : 95)
Query Neighborhood Hits	137	Target Neighborhood Hits	211	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA22_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.191117 (rank : 100)
Query Neighborhood Hits	137	Target Neighborhood Hits	225	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA23_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.186257 (rank : 101)
Query Neighborhood Hits	137	Target Neighborhood Hits	235	Shared Neighborhood Hits	50
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.193174 (rank : 98)
Query Neighborhood Hits	137	Target Neighborhood Hits	245	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA24_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.191167 (rank : 99)
Query Neighborhood Hits	137	Target Neighborhood Hits	230	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA25_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.183374 (rank : 103)
Query Neighborhood Hits	137	Target Neighborhood Hits	213	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA28_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.259283 (rank : 81)
Query Neighborhood Hits	137	Target Neighborhood Hits	244	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA28_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.268127 (rank : 79)
Query Neighborhood Hits	137	Target Neighborhood Hits	241	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA29_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.185017 (rank : 102)
Query Neighborhood Hits	137	Target Neighborhood Hits	247	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA30_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.092197 (rank : 135)
Query Neighborhood Hits	137	Target Neighborhood Hits	391	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA32_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.140401 (rank : 120)
Query Neighborhood Hits	137	Target Neighborhood Hits	216	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA32_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.137865 (rank : 122)
Query Neighborhood Hits	137	Target Neighborhood Hits	219	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA33_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.253184 (rank : 82)
Query Neighborhood Hits	137	Target Neighborhood Hits	264	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA33_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.225288 (rank : 91)
Query Neighborhood Hits	137	Target Neighborhood Hits	231	Shared Neighborhood Hits	44
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM2_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.113730 (rank : 128)
Query Neighborhood Hits	137	Target Neighborhood Hits	175	Shared Neighborhood Hits	35
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADAM2_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.146349 (rank : 117)
Query Neighborhood Hits	137	Target Neighborhood Hits	209	Shared Neighborhood Hits	42
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADAM7_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.234552 (rank : 87)
Query Neighborhood Hits	137	Target Neighborhood Hits	221	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.232625 (rank : 88)
Query Neighborhood Hits	137	Target Neighborhood Hits	200	Shared Neighborhood Hits	43
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM8_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.278002 (rank : 76)
Query Neighborhood Hits	137	Target Neighborhood Hits	327	Shared Neighborhood Hits	54
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM8_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.277568 (rank : 77)
Query Neighborhood Hits	137	Target Neighborhood Hits	326	Shared Neighborhood Hits	55
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADAM9_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.225709 (rank : 90)
Query Neighborhood Hits	137	Target Neighborhood Hits	243	Shared Neighborhood Hits	47
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADAM9_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.236877 (rank : 86)
Query Neighborhood Hits	137	Target Neighborhood Hits	325	Shared Neighborhood Hits	49
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADEC1_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.251146 (rank : 83)
Query Neighborhood Hits	137	Target Neighborhood Hits	80	Shared Neighborhood Hits	30
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADEC1_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.202270 (rank : 94)
Query Neighborhood Hits	137	Target Neighborhood Hits	85	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADM1A_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.194366 (rank : 97)
Query Neighborhood Hits	137	Target Neighborhood Hits	230	Shared Neighborhood Hits	48
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADM1B_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.204181 (rank : 93)
Query Neighborhood Hits	137	Target Neighborhood Hits	236	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

CD97_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.056970 (rank : 160)
Query Neighborhood Hits	137	Target Neighborhood Hits	353	Shared Neighborhood Hits	26
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.054215 (rank : 165)
Query Neighborhood Hits	137	Target Neighborhood Hits	295	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CO8A_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.357064 (rank : 67)
Query Neighborhood Hits	137	Target Neighborhood Hits	200	Shared Neighborhood Hits	72
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.353947 (rank : 68)
Query Neighborhood Hits	137	Target Neighborhood Hits	182	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.307766 (rank : 75)
Query Neighborhood Hits	137	Target Neighborhood Hits	199	Shared Neighborhood Hits	66
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.346521 (rank : 70)
Query Neighborhood Hits	137	Target Neighborhood Hits	224	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

COMP_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.074489 (rank : 142)
Query Neighborhood Hits	137	Target Neighborhood Hits	258	Shared Neighborhood Hits	20
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.073924 (rank : 143)
Query Neighborhood Hits	137	Target Neighborhood Hits	290	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CRIM1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.056391 (rank : 163)
Query Neighborhood Hits	137	Target Neighborhood Hits	362	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

ELTD1_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.065148 (rank : 151)
Query Neighborhood Hits	137	Target Neighborhood Hits	269	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.061644 (rank : 153)
Query Neighborhood Hits	137	Target Neighborhood Hits	288	Shared Neighborhood Hits	24
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.058206 (rank : 157)
Query Neighborhood Hits	137	Target Neighborhood Hits	382	Shared Neighborhood Hits	32
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.059260 (rank : 155)
Query Neighborhood Hits	137	Target Neighborhood Hits	349	Shared Neighborhood Hits	31
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.053404 (rank : 167)
Query Neighborhood Hits	137	Target Neighborhood Hits	345	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EMR3_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.051396 (rank : 172)
Query Neighborhood Hits	137	Target Neighborhood Hits	245	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EMR4_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.057038 (rank : 159)
Query Neighborhood Hits	137	Target Neighborhood Hits	191	Shared Neighborhood Hits	15
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

GP110_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.056924 (rank : 161)
Query Neighborhood Hits	137	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

GP110_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.053814 (rank : 166)
Query Neighborhood Hits	137	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

GP113_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.064295 (rank : 152)
Query Neighborhood Hits	137	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

GP115_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.052114 (rank : 171)
Query Neighborhood Hits	137	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

GP115_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.050786 (rank : 175)
Query Neighborhood Hits	137	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

GP116_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.057465 (rank : 158)
Query Neighborhood Hits	137	Target Neighborhood Hits	167	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP128_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.052665 (rank : 169)
Query Neighborhood Hits	137	Target Neighborhood Hits	135	Shared Neighborhood Hits	9
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP133_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.054557 (rank : 164)
Query Neighborhood Hits	137	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GPR97_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.051060 (rank : 174)
Query Neighborhood Hits	137	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

KR102_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.061093 (rank : 154)
Query Neighborhood Hits	137	Target Neighborhood Hits	264	Shared Neighborhood Hits	36
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR104_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.067059 (rank : 149)
Query Neighborhood Hits	137	Target Neighborhood Hits	313	Shared Neighborhood Hits	41
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR107_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.058380 (rank : 156)
Query Neighborhood Hits	137	Target Neighborhood Hits	330	Shared Neighborhood Hits	42
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KRA51_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.056596 (rank : 162)
Query Neighborhood Hits	137	Target Neighborhood Hits	288	Shared Neighborhood Hits	38
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA93_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.052572 (rank : 170)
Query Neighborhood Hits	137	Target Neighborhood Hits	203	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

RSPO1_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.093179 (rank : 133)
Query Neighborhood Hits	137	Target Neighborhood Hits	101	Shared Neighborhood Hits	40
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO1_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.079361 (rank : 138)
Query Neighborhood Hits	137	Target Neighborhood Hits	85	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO2_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.051290 (rank : 173)
Query Neighborhood Hits	137	Target Neighborhood Hits	90	Shared Neighborhood Hits	28
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO3_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.070148 (rank : 148)
Query Neighborhood Hits	137	Target Neighborhood Hits	128	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.066566 (rank : 150)
Query Neighborhood Hits	137	Target Neighborhood Hits	120	Shared Neighborhood Hits	33
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.071430 (rank : 145)
Query Neighborhood Hits	137	Target Neighborhood Hits	110	Shared Neighborhood Hits	39
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.093026 (rank : 134)
Query Neighborhood Hits	137	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SPON2_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.111553 (rank : 129)
Query Neighborhood Hits	137	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

SPON2_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.094435 (rank : 132)
Query Neighborhood Hits	137	Target Neighborhood Hits	42	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

TSP3_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.075347 (rank : 140)
Query Neighborhood Hits	137	Target Neighborhood Hits	250	Shared Neighborhood Hits	20
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.074843 (rank : 141)
Query Neighborhood Hits	137	Target Neighborhood Hits	247	Shared Neighborhood Hits	20
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.070976 (rank : 146)
Query Neighborhood Hits	137	Target Neighborhood Hits	277	Shared Neighborhood Hits	20
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.070500 (rank : 147)
Query Neighborhood Hits	137	Target Neighborhood Hits	276	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

ZAN_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.052756 (rank : 168)
Query Neighborhood Hits	137	Target Neighborhood Hits	808	Shared Neighborhood Hits	60
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

ATL2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	137	Target Neighborhood Hits	137	Shared Neighborhood Hits	137
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATL2_HUMAN
NC score	0.997938 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	137	Target Neighborhood Hits	125	Shared Neighborhood Hits	111
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL5_HUMAN
NC score	0.927083 (rank : 3)	θ value	8.04462e-41 (rank : 16)
Query Neighborhood Hits	137	Target Neighborhood Hits	103	Shared Neighborhood Hits	74
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATL1_HUMAN
NC score	0.905776 (rank : 4)	θ value	1.6813e-30 (rank : 33)
Query Neighborhood Hits	137	Target Neighborhood Hits	93	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL1_MOUSE
NC score	0.903853 (rank : 5)	θ value	4.42448e-31 (rank : 32)
Query Neighborhood Hits	137	Target Neighborhood Hits	80	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATS13_HUMAN
NC score	0.876848 (rank : 6)	θ value	1.57365e-28 (rank : 35)
Query Neighborhood Hits	137	Target Neighborhood Hits	238	Shared Neighborhood Hits	83
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_MOUSE
NC score	0.875688 (rank : 7)	θ value	1.73987e-27 (rank : 36)
Query Neighborhood Hits	137	Target Neighborhood Hits	227	Shared Neighborhood Hits	87
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS18_MOUSE
NC score	0.875146 (rank : 8)	θ value	1.36902e-48 (rank : 6)
Query Neighborhood Hits	137	Target Neighborhood Hits	163	Shared Neighborhood Hits	88
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS18_HUMAN
NC score	0.867779 (rank : 9)	θ value	1.15895e-47 (rank : 8)
Query Neighborhood Hits	137	Target Neighborhood Hits	169	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS19_MOUSE
NC score	0.867209 (rank : 10)	θ value	5.95217e-44 (rank : 12)
Query Neighborhood Hits	137	Target Neighborhood Hits	188	Shared Neighborhood Hits	86
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS9_HUMAN
NC score	0.867094 (rank : 11)	θ value	3.2585e-50 (rank : 3)
Query Neighborhood Hits	137	Target Neighborhood Hits	219	Shared Neighborhood Hits	98
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS2_HUMAN
NC score	0.866669 (rank : 12)	θ value	8.32485e-38 (rank : 21)
Query Neighborhood Hits	137	Target Neighborhood Hits	179	Shared Neighborhood Hits	83
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS19_HUMAN
NC score	0.864595 (rank : 13)	θ value	1.91475e-42 (rank : 15)
Query Neighborhood Hits	137	Target Neighborhood Hits	203	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS8_MOUSE
NC score	0.864453 (rank : 14)	θ value	1.98146e-39 (rank : 19)
Query Neighborhood Hits	137	Target Neighborhood Hits	139	Shared Neighborhood Hits	77
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS4_HUMAN
NC score	0.864208 (rank : 15)	θ value	1.52067e-31 (rank : 30)
Query Neighborhood Hits	137	Target Neighborhood Hits	138	Shared Neighborhood Hits	75
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS2_MOUSE
NC score	0.863943 (rank : 16)	θ value	3.86705e-35 (rank : 24)
Query Neighborhood Hits	137	Target Neighborhood Hits	179	Shared Neighborhood Hits	82
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS16_MOUSE
NC score	0.863545 (rank : 17)	θ value	1.51363e-47 (rank : 9)
Query Neighborhood Hits	137	Target Neighborhood Hits	179	Shared Neighborhood Hits	89
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS4_MOUSE
NC score	0.862881 (rank : 18)	θ value	1.52067e-31 (rank : 31)
Query Neighborhood Hits	137	Target Neighborhood Hits	145	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS16_HUMAN
NC score	0.862159 (rank : 19)	θ value	2.1121e-49 (rank : 5)
Query Neighborhood Hits	137	Target Neighborhood Hits	208	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS8_HUMAN
NC score	0.862144 (rank : 20)	θ value	2.34062e-40 (rank : 17)
Query Neighborhood Hits	137	Target Neighborhood Hits	145	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS12_MOUSE
NC score	0.860185 (rank : 21)	θ value	3.37202e-47 (rank : 10)
Query Neighborhood Hits	137	Target Neighborhood Hits	220	Shared Neighborhood Hits	87
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS12_HUMAN
NC score	0.859896 (rank : 22)	θ value	1.15895e-47 (rank : 7)
Query Neighborhood Hits	137	Target Neighborhood Hits	251	Shared Neighborhood Hits	87
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS20_MOUSE
NC score	0.858891 (rank : 23)	θ value	2.04573e-44 (rank : 11)
Query Neighborhood Hits	137	Target Neighborhood Hits	225	Shared Neighborhood Hits	94
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS17_HUMAN
NC score	0.858886 (rank : 24)	θ value	2.34606e-32 (rank : 29)
Query Neighborhood Hits	137	Target Neighborhood Hits	194	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS15_HUMAN
NC score	0.858245 (rank : 25)	θ value	1.12514e-34 (rank : 25)
Query Neighborhood Hits	137	Target Neighborhood Hits	151	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS3_HUMAN
NC score	0.856655 (rank : 26)	θ value	1.6774e-38 (rank : 20)
Query Neighborhood Hits	137	Target Neighborhood Hits	179	Shared Neighborhood Hits	87
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS1_HUMAN
NC score	0.854516 (rank : 27)	θ value	9.52487e-34 (rank : 27)
Query Neighborhood Hits	137	Target Neighborhood Hits	159	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS6_HUMAN
NC score	0.853063 (rank : 28)	θ value	9.48078e-50 (rank : 4)
Query Neighborhood Hits	137	Target Neighborhood Hits	141	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS1_MOUSE
NC score	0.853040 (rank : 29)	θ value	9.52487e-34 (rank : 28)
Query Neighborhood Hits	137	Target Neighborhood Hits	158	Shared Neighborhood Hits	88
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS14_HUMAN
NC score	0.850984 (rank : 30)	θ value	1.51715e-39 (rank : 18)
Query Neighborhood Hits	137	Target Neighborhood Hits	382	Shared Neighborhood Hits	87
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS20_HUMAN
NC score	0.850417 (rank : 31)	θ value	5.95217e-44 (rank : 13)
Query Neighborhood Hits	137	Target Neighborhood Hits	192	Shared Neighborhood Hits	92
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS7_HUMAN
NC score	0.844200 (rank : 32)	θ value	1.32601e-43 (rank : 14)
Query Neighborhood Hits	137	Target Neighborhood Hits	169	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS5_HUMAN
NC score	0.841287 (rank : 33)	θ value	2.42216e-37 (rank : 22)
Query Neighborhood Hits	137	Target Neighborhood Hits	141	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS5_MOUSE
NC score	0.839426 (rank : 34)	θ value	3.16345e-37 (rank : 23)
Query Neighborhood Hits	137	Target Neighborhood Hits	147	Shared Neighborhood Hits	77
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATL3_HUMAN
NC score	0.775538 (rank : 35)	θ value	5.584e-34 (rank : 26)
Query Neighborhood Hits	137	Target Neighborhood Hits	414	Shared Neighborhood Hits	90
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

PROP_HUMAN
NC score	0.695190 (rank : 36)	θ value	3.52202e-12 (rank : 48)
Query Neighborhood Hits	137	Target Neighborhood Hits	126	Shared Neighborhood Hits	78
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
NC score	0.688126 (rank : 37)	θ value	5.62301e-10 (rank : 52)
Query Neighborhood Hits	137	Target Neighborhood Hits	165	Shared Neighborhood Hits	83
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

SPON1_HUMAN
NC score	0.668456 (rank : 38)	θ value	3.40345e-15 (rank : 42)
Query Neighborhood Hits	137	Target Neighborhood Hits	117	Shared Neighborhood Hits	84
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
NC score	0.665398 (rank : 39)	θ value	9.90251e-15 (rank : 43)
Query Neighborhood Hits	137	Target Neighborhood Hits	123	Shared Neighborhood Hits	86
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

CI094_HUMAN
NC score	0.626129 (rank : 40)	θ value	7.06379e-29 (rank : 34)
Query Neighborhood Hits	137	Target Neighborhood Hits	310	Shared Neighborhood Hits	75
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

THSD1_HUMAN
NC score	0.549218 (rank : 41)	θ value	0.000121331 (rank : 57)
Query Neighborhood Hits	137	Target Neighborhood Hits	136	Shared Neighborhood Hits	71
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

BAI2_HUMAN
NC score	0.531213 (rank : 42)	θ value	2.20605e-14 (rank : 45)
Query Neighborhood Hits	137	Target Neighborhood Hits	332	Shared Neighborhood Hits	85
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI1_MOUSE
NC score	0.530691 (rank : 43)	θ value	3.07829e-16 (rank : 37)
Query Neighborhood Hits	137	Target Neighborhood Hits	340	Shared Neighborhood Hits	84
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_MOUSE
NC score	0.529342 (rank : 44)	θ value	1.29331e-14 (rank : 44)
Query Neighborhood Hits	137	Target Neighborhood Hits	323	Shared Neighborhood Hits	84
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI1_HUMAN
NC score	0.528141 (rank : 45)	θ value	8.95645e-16 (rank : 38)
Query Neighborhood Hits	137	Target Neighborhood Hits	375	Shared Neighborhood Hits	86
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI3_HUMAN
NC score	0.521688 (rank : 46)	θ value	1.02475e-11 (rank : 49)
Query Neighborhood Hits	137	Target Neighborhood Hits	246	Shared Neighborhood Hits	80
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
NC score	0.521293 (rank : 47)	θ value	1.33837e-11 (rank : 50)
Query Neighborhood Hits	137	Target Neighborhood Hits	250	Shared Neighborhood Hits	85
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

TSP1_HUMAN
NC score	0.519532 (rank : 48)	θ value	8.95645e-16 (rank : 39)
Query Neighborhood Hits	137	Target Neighborhood Hits	389	Shared Neighborhood Hits	102
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
NC score	0.518850 (rank : 49)	θ value	2.60593e-15 (rank : 40)
Query Neighborhood Hits	137	Target Neighborhood Hits	396	Shared Neighborhood Hits	102
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

THSD1_MOUSE
NC score	0.512458 (rank : 50)	θ value	0.00298849 (rank : 66)
Query Neighborhood Hits	137	Target Neighborhood Hits	153	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TSP2_MOUSE
NC score	0.511406 (rank : 51)	θ value	1.33837e-11 (rank : 51)
Query Neighborhood Hits	137	Target Neighborhood Hits	352	Shared Neighborhood Hits	99
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_HUMAN
NC score	0.506447 (rank : 52)	θ value	5.62301e-10 (rank : 53)
Query Neighborhood Hits	137	Target Neighborhood Hits	359	Shared Neighborhood Hits	99
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

SEM5A_HUMAN
NC score	0.470691 (rank : 53)	θ value	4.91457e-14 (rank : 46)
Query Neighborhood Hits	137	Target Neighborhood Hits	177	Shared Neighborhood Hits	83
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

UNC5A_MOUSE
NC score	0.467870 (rank : 54)	θ value	0.000602161 (rank : 59)
Query Neighborhood Hits	137	Target Neighborhood Hits	203	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

SEM5A_MOUSE
NC score	0.460086 (rank : 55)	θ value	2.0648e-12 (rank : 47)
Query Neighborhood Hits	137	Target Neighborhood Hits	162	Shared Neighborhood Hits	83
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

UNC5B_MOUSE
NC score	0.453912 (rank : 56)	θ value	0.0148317 (rank : 68)
Query Neighborhood Hits	137	Target Neighborhood Hits	226	Shared Neighborhood Hits	71
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5B_HUMAN
NC score	0.451377 (rank : 57)	θ value	0.0193708 (rank : 69)
Query Neighborhood Hits	137	Target Neighborhood Hits	225	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

SEM5B_MOUSE
NC score	0.450714 (rank : 58)	θ value	5.81887e-07 (rank : 55)
Query Neighborhood Hits	137	Target Neighborhood Hits	190	Shared Neighborhood Hits	85
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM5B_HUMAN
NC score	0.447994 (rank : 59)	θ value	1.29631e-06 (rank : 56)
Query Neighborhood Hits	137	Target Neighborhood Hits	178	Shared Neighborhood Hits	85
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SSPO_MOUSE
NC score	0.442323 (rank : 60)	θ value	9.59137e-10 (rank : 54)
Query Neighborhood Hits	137	Target Neighborhood Hits	800	Shared Neighborhood Hits	111
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

UNC5C_MOUSE
NC score	0.440915 (rank : 61)	θ value	0.00102713 (rank : 61)
Query Neighborhood Hits	137	Target Neighborhood Hits	225	Shared Neighborhood Hits	72
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5C_HUMAN
NC score	0.440679 (rank : 62)	θ value	0.00102713 (rank : 60)
Query Neighborhood Hits	137	Target Neighborhood Hits	226	Shared Neighborhood Hits	72
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5D_HUMAN
NC score	0.432077 (rank : 63)	θ value	0.00228821 (rank : 63)
Query Neighborhood Hits	137	Target Neighborhood Hits	267	Shared Neighborhood Hits	72
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
NC score	0.428657 (rank : 64)	θ value	0.00228821 (rank : 64)
Query Neighborhood Hits	137	Target Neighborhood Hits	268	Shared Neighborhood Hits	72
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

CILP2_HUMAN
NC score	0.425413 (rank : 65)	θ value	0.00020696 (rank : 58)
Query Neighborhood Hits	137	Target Neighborhood Hits	307	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CO6_HUMAN
NC score	0.382099 (rank : 66)	θ value	0.62314 (rank : 80)
Query Neighborhood Hits	137	Target Neighborhood Hits	331	Shared Neighborhood Hits	82
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO8A_HUMAN
NC score	0.357064 (rank : 67)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	137	Target Neighborhood Hits	200	Shared Neighborhood Hits	72
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_MOUSE
NC score	0.353947 (rank : 68)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	137	Target Neighborhood Hits	182	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

UNC5A_HUMAN
NC score	0.349868 (rank : 69)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	137	Target Neighborhood Hits	198	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

CO8B_MOUSE
NC score	0.346521 (rank : 70)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	137	Target Neighborhood Hits	224	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO7_HUMAN
NC score	0.323323 (rank : 71)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	137	Target Neighborhood Hits	278	Shared Neighborhood Hits	72
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CILP1_MOUSE
NC score	0.319728 (rank : 72)	θ value	0.0148317 (rank : 67)
Query Neighborhood Hits	137	Target Neighborhood Hits	282	Shared Neighborhood Hits	77
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_HUMAN
NC score	0.314792 (rank : 73)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	137	Target Neighborhood Hits	266	Shared Neighborhood Hits	74
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

HMCN1_HUMAN
NC score	0.313505 (rank : 74)	θ value	3.40345e-15 (rank : 41)
Query Neighborhood Hits	137	Target Neighborhood Hits	983	Shared Neighborhood Hits	101
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

CO8B_HUMAN
NC score	0.307766 (rank : 75)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	137	Target Neighborhood Hits	199	Shared Neighborhood Hits	66
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ADAM8_HUMAN
NC score	0.278002 (rank : 76)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	137	Target Neighborhood Hits	327	Shared Neighborhood Hits	54
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM8_MOUSE
NC score	0.277568 (rank : 77)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	137	Target Neighborhood Hits	326	Shared Neighborhood Hits	55
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADA19_MOUSE
NC score	0.276991 (rank : 78)	θ value	0.163984 (rank : 77)
Query Neighborhood Hits	137	Target Neighborhood Hits	315	Shared Neighborhood Hits	52
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA28_MOUSE
NC score	0.268127 (rank : 79)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	137	Target Neighborhood Hits	241	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA19_HUMAN
NC score	0.261541 (rank : 80)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	137	Target Neighborhood Hits	381	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA28_HUMAN
NC score	0.259283 (rank : 81)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	137	Target Neighborhood Hits	244	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA33_HUMAN
NC score	0.253184 (rank : 82)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	137	Target Neighborhood Hits	264	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADEC1_HUMAN
NC score	0.251146 (rank : 83)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	137	Target Neighborhood Hits	80	Shared Neighborhood Hits	30
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADA12_HUMAN
NC score	0.249129 (rank : 84)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	137	Target Neighborhood Hits	224	Shared Neighborhood Hits	45
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA12_MOUSE
NC score	0.244187 (rank : 85)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	137	Target Neighborhood Hits	474	Shared Neighborhood Hits	50
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADAM9_MOUSE
NC score	0.236877 (rank : 86)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	137	Target Neighborhood Hits	325	Shared Neighborhood Hits	49
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADAM7_HUMAN
NC score	0.234552 (rank : 87)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	137	Target Neighborhood Hits	221	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
NC score	0.232625 (rank : 88)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	137	Target Neighborhood Hits	200	Shared Neighborhood Hits	43
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADA15_HUMAN
NC score	0.231865 (rank : 89)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	137	Target Neighborhood Hits	288	Shared Neighborhood Hits	47
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADAM9_HUMAN
NC score	0.225709 (rank : 90)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	137	Target Neighborhood Hits	243	Shared Neighborhood Hits	47
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADA33_MOUSE
NC score	0.225288 (rank : 91)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	137	Target Neighborhood Hits	231	Shared Neighborhood Hits	44
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA15_MOUSE
NC score	0.205810 (rank : 92)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	137	Target Neighborhood Hits	324	Shared Neighborhood Hits	54
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADM1B_MOUSE
NC score	0.204181 (rank : 93)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	137	Target Neighborhood Hits	236	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADEC1_MOUSE
NC score	0.202270 (rank : 94)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	137	Target Neighborhood Hits	85	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADA22_HUMAN
NC score	0.200855 (rank : 95)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	137	Target Neighborhood Hits	211	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA21_MOUSE
NC score	0.194776 (rank : 96)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	137	Target Neighborhood Hits	172	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADM1A_MOUSE
NC score	0.194366 (rank : 97)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	137	Target Neighborhood Hits	230	Shared Neighborhood Hits	48
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA23_MOUSE
NC score	0.193174 (rank : 98)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	137	Target Neighborhood Hits	245	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA24_MOUSE
NC score	0.191167 (rank : 99)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	137	Target Neighborhood Hits	230	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA22_MOUSE
NC score	0.191117 (rank : 100)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	137	Target Neighborhood Hits	225	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA23_HUMAN
NC score	0.186257 (rank : 101)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	137	Target Neighborhood Hits	235	Shared Neighborhood Hits	50
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA29_HUMAN
NC score	0.185017 (rank : 102)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	137	Target Neighborhood Hits	247	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA25_MOUSE
NC score	0.183374 (rank : 103)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	137	Target Neighborhood Hits	213	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

WISP1_MOUSE
NC score	0.180499 (rank : 104)	θ value	0.0736092 (rank : 73)
Query Neighborhood Hits	137	Target Neighborhood Hits	123	Shared Neighborhood Hits	60
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

ADA21_HUMAN
NC score	0.180397 (rank : 105)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	137	Target Neighborhood Hits	181	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

WISP2_MOUSE
NC score	0.180369 (rank : 106)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	137	Target Neighborhood Hits	129	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

WISP2_HUMAN
NC score	0.180297 (rank : 107)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	137	Target Neighborhood Hits	126	Shared Neighborhood Hits	63
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

AD26A_MOUSE
NC score	0.179008 (rank : 108)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	137	Target Neighborhood Hits	165	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA11_MOUSE
NC score	0.174206 (rank : 109)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	137	Target Neighborhood Hits	263	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

WISP1_HUMAN
NC score	0.173338 (rank : 110)	θ value	0.0961366 (rank : 75)
Query Neighborhood Hits	137	Target Neighborhood Hits	121	Shared Neighborhood Hits	60
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

ADA10_HUMAN
NC score	0.164992 (rank : 111)	θ value	0.00175202 (rank : 62)
Query Neighborhood Hits	137	Target Neighborhood Hits	189	Shared Neighborhood Hits	41
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
NC score	0.164059 (rank : 112)	θ value	0.00298849 (rank : 65)
Query Neighborhood Hits	137	Target Neighborhood Hits	194	Shared Neighborhood Hits	41
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

NOV_MOUSE
NC score	0.159579 (rank : 113)	θ value	0.0252991 (rank : 70)
Query Neighborhood Hits	137	Target Neighborhood Hits	130	Shared Neighborhood Hits	57
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

CYR61_HUMAN
NC score	0.151523 (rank : 114)	θ value	1.38821 (rank : 90)
Query Neighborhood Hits	137	Target Neighborhood Hits	159	Shared Neighborhood Hits	66
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

ADA11_HUMAN
NC score	0.151513 (rank : 115)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	137	Target Neighborhood Hits	259	Shared Neighborhood Hits	43
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

NOV_HUMAN
NC score	0.146463 (rank : 116)	θ value	0.0563607 (rank : 71)
Query Neighborhood Hits	137	Target Neighborhood Hits	128	Shared Neighborhood Hits	52
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

ADAM2_MOUSE
NC score	0.146349 (rank : 117)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	137	Target Neighborhood Hits	209	Shared Neighborhood Hits	42
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

WISP3_HUMAN
NC score	0.146255 (rank : 118)	θ value	1.06291 (rank : 89)
Query Neighborhood Hits	137	Target Neighborhood Hits	87	Shared Neighborhood Hits	45
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

ADA17_MOUSE
NC score	0.145614 (rank : 119)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	137	Target Neighborhood Hits	201	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA32_HUMAN
NC score	0.140401 (rank : 120)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	137	Target Neighborhood Hits	216	Shared Neighborhood Hits	43
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA20_HUMAN
NC score	0.140194 (rank : 121)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	137	Target Neighborhood Hits	143	Shared Neighborhood Hits	40
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA32_MOUSE
NC score	0.137865 (rank : 122)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	137	Target Neighborhood Hits	219	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

CYR61_MOUSE
NC score	0.137109 (rank : 123)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	137	Target Neighborhood Hits	156	Shared Neighborhood Hits	61
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

ADA17_HUMAN
NC score	0.136000 (rank : 124)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	137	Target Neighborhood Hits	223	Shared Neighborhood Hits	46
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

CTGF_MOUSE
NC score	0.127679 (rank : 125)	θ value	0.62314 (rank : 81)
Query Neighborhood Hits	137	Target Neighborhood Hits	124	Shared Neighborhood Hits	53
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

ADA18_MOUSE
NC score	0.127484 (rank : 126)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	137	Target Neighborhood Hits	227	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

CTGF_HUMAN
NC score	0.122517 (rank : 127)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	137	Target Neighborhood Hits	128	Shared Neighborhood Hits	53
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

ADAM2_HUMAN
NC score	0.113730 (rank : 128)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	137	Target Neighborhood Hits	175	Shared Neighborhood Hits	35
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

SPON2_HUMAN
NC score	0.111553 (rank : 129)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	137	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

ADA18_HUMAN
NC score	0.104348 (rank : 130)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	137	Target Neighborhood Hits	184	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

FRAS1_MOUSE
NC score	0.102072 (rank : 131)	θ value	0.62314 (rank : 82)
Query Neighborhood Hits	137	Target Neighborhood Hits	747	Shared Neighborhood Hits	82
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

SPON2_MOUSE
NC score	0.094435 (rank : 132)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	137	Target Neighborhood Hits	42	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

RSPO1_HUMAN
NC score	0.093179 (rank : 133)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	137	Target Neighborhood Hits	101	Shared Neighborhood Hits	40
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO4_MOUSE
NC score	0.093026 (rank : 134)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	137	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

ADA30_HUMAN
NC score	0.092197 (rank : 135)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	137	Target Neighborhood Hits	391	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

KRA92_HUMAN
NC score	0.085357 (rank : 136)	θ value	0.0961366 (rank : 74)
Query Neighborhood Hits	137	Target Neighborhood Hits	198	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

FRAS1_HUMAN
NC score	0.084278 (rank : 137)	θ value	1.38821 (rank : 92)
Query Neighborhood Hits	137	Target Neighborhood Hits	759	Shared Neighborhood Hits	73
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

RSPO1_MOUSE
NC score	0.079361 (rank : 138)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	137	Target Neighborhood Hits	85	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

KR106_HUMAN
NC score	0.076260 (rank : 139)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	137	Target Neighborhood Hits	347	Shared Neighborhood Hits	46
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

TSP3_HUMAN
NC score	0.075347 (rank : 140)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	137	Target Neighborhood Hits	250	Shared Neighborhood Hits	20
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
NC score	0.074843 (rank : 141)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	137	Target Neighborhood Hits	247	Shared Neighborhood Hits	20
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

COMP_HUMAN
NC score	0.074489 (rank : 142)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	137	Target Neighborhood Hits	258	Shared Neighborhood Hits	20
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
NC score	0.073924 (rank : 143)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	137	Target Neighborhood Hits	290	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

KRA98_HUMAN
NC score	0.072192 (rank : 144)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	137	Target Neighborhood Hits	185	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

RSPO4_HUMAN
NC score	0.071430 (rank : 145)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	137	Target Neighborhood Hits	110	Shared Neighborhood Hits	39
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

TSP4_HUMAN
NC score	0.070976 (rank : 146)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	137	Target Neighborhood Hits	277	Shared Neighborhood Hits	20
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
NC score	0.070500 (rank : 147)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	137	Target Neighborhood Hits	276	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

RSPO3_HUMAN
NC score	0.070148 (rank : 148)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	137	Target Neighborhood Hits	128	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

KR104_HUMAN
NC score	0.067059 (rank : 149)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	137	Target Neighborhood Hits	313	Shared Neighborhood Hits	41
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

RSPO3_MOUSE
NC score	0.066566 (rank : 150)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	137	Target Neighborhood Hits	120	Shared Neighborhood Hits	33
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

ELTD1_HUMAN
NC score	0.065148 (rank : 151)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	137	Target Neighborhood Hits	269	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

GP113_HUMAN
NC score	0.064295 (rank : 152)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	137	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

ELTD1_MOUSE
NC score	0.061644 (rank : 153)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	137	Target Neighborhood Hits	288	Shared Neighborhood Hits	24
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

KR102_HUMAN
NC score	0.061093 (rank : 154)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	137	Target Neighborhood Hits	264	Shared Neighborhood Hits	36
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

EMR1_MOUSE
NC score	0.059260 (rank : 155)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	137	Target Neighborhood Hits	349	Shared Neighborhood Hits	31
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

KR107_HUMAN
NC score	0.058380 (rank : 156)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	137	Target Neighborhood Hits	330	Shared Neighborhood Hits	42
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

EMR1_HUMAN
NC score	0.058206 (rank : 157)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	137	Target Neighborhood Hits	382	Shared Neighborhood Hits	32
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

GP116_HUMAN
NC score	0.057465 (rank : 158)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	137	Target Neighborhood Hits	167	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

EMR4_MOUSE
NC score	0.057038 (rank : 159)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	137	Target Neighborhood Hits	191	Shared Neighborhood Hits	15
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

CD97_HUMAN
NC score	0.056970 (rank : 160)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	137	Target Neighborhood Hits	353	Shared Neighborhood Hits	26
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

GP110_HUMAN
NC score	0.056924 (rank : 161)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	137	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

KRA51_HUMAN
NC score	0.056596 (rank : 162)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	137	Target Neighborhood Hits	288	Shared Neighborhood Hits	38
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

CRIM1_HUMAN
NC score	0.056391 (rank : 163)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	137	Target Neighborhood Hits	362	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

GP133_HUMAN
NC score	0.054557 (rank : 164)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	137	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

CD97_MOUSE
NC score	0.054215 (rank : 165)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	137	Target Neighborhood Hits	295	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

GP110_MOUSE
NC score	0.053814 (rank : 166)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	137	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

EMR2_HUMAN
NC score	0.053404 (rank : 167)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	137	Target Neighborhood Hits	345	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

ZAN_MOUSE
NC score	0.052756 (rank : 168)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	137	Target Neighborhood Hits	808	Shared Neighborhood Hits	60
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

GP128_HUMAN
NC score	0.052665 (rank : 169)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	137	Target Neighborhood Hits	135	Shared Neighborhood Hits	9
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

KRA93_HUMAN
NC score	0.052572 (rank : 170)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	137	Target Neighborhood Hits	203	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

GP115_HUMAN
NC score	0.052114 (rank : 171)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	137	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

EMR3_HUMAN
NC score	0.051396 (rank : 172)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	137	Target Neighborhood Hits	245	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

RSPO2_HUMAN
NC score	0.051290 (rank : 173)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	137	Target Neighborhood Hits	90	Shared Neighborhood Hits	28
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

GPR97_MOUSE
NC score	0.051060 (rank : 174)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	137	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

GP115_MOUSE
NC score	0.050786 (rank : 175)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	137	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

SREC2_MOUSE
NC score	0.046112 (rank : 176)	θ value	0.125558 (rank : 76)
Query Neighborhood Hits	137	Target Neighborhood Hits	605	Shared Neighborhood Hits	44
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

MEGF6_HUMAN
NC score	0.045747 (rank : 177)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	137	Target Neighborhood Hits	671	Shared Neighborhood Hits	62
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

SREC2_HUMAN
NC score	0.044217 (rank : 178)	θ value	0.0736092 (rank : 72)
Query Neighborhood Hits	137	Target Neighborhood Hits	645	Shared Neighborhood Hits	38
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TENX_HUMAN
NC score	0.042742 (rank : 179)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	137	Target Neighborhood Hits	789	Shared Neighborhood Hits	53
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

NFX1_HUMAN
NC score	0.042254 (rank : 180)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	137	Target Neighborhood Hits	405	Shared Neighborhood Hits	31
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

TRBM_MOUSE
NC score	0.039665 (rank : 181)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	137	Target Neighborhood Hits	361	Shared Neighborhood Hits	31
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

NOTC3_HUMAN
NC score	0.038951 (rank : 182)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	137	Target Neighborhood Hits	1062	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

CORT_MOUSE
NC score	0.037131 (rank : 183)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	137	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	P56469, Q9R1P8	Gene names	Cort
Domain Architecture
Description	Cortistatin precursor [Contains: Cortistatin-14].

LRP1B_HUMAN
NC score	0.034336 (rank : 184)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	137	Target Neighborhood Hits	602	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

FBLN5_HUMAN
NC score	0.032399 (rank : 185)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	137	Target Neighborhood Hits	329	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
NC score	0.031702 (rank : 186)	θ value	1.38821 (rank : 91)
Query Neighborhood Hits	137	Target Neighborhood Hits	317	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

NOTC4_HUMAN
NC score	0.031297 (rank : 187)	θ value	1.06291 (rank : 88)
Query Neighborhood Hits	137	Target Neighborhood Hits	905	Shared Neighborhood Hits	49
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

LRP8_MOUSE
NC score	0.031188 (rank : 188)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	137	Target Neighborhood Hits	385	Shared Neighborhood Hits	31
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

FBLN3_MOUSE
NC score	0.028552 (rank : 189)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	137	Target Neighborhood Hits	279	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

LAMC1_MOUSE
NC score	0.025650 (rank : 190)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	137	Target Neighborhood Hits	856	Shared Neighborhood Hits	30
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_HUMAN
NC score	0.022833 (rank : 191)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	137	Target Neighborhood Hits	922	Shared Neighborhood Hits	33
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

KRA33_HUMAN
NC score	0.021603 (rank : 192)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	137	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYR6, Q52LP0	Gene names	KRTAP3-3, KAP3.3, KRTAP3.3
Domain Architecture
Description	Keratin-associated protein 3-3 (Keratin-associated protein 3.3) (High sulfur keratin-associated protein 3.3).

KRA32_HUMAN
NC score	0.021044 (rank : 193)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	137	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYR7	Gene names	KRTAP3-2, KAP3.2, KRTAP3.2
Domain Architecture
Description	Keratin-associated protein 3-2 (Keratin-associated protein 3.2) (High sulfur keratin-associated protein 3.2).

TNR4_HUMAN
NC score	0.021042 (rank : 194)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	137	Target Neighborhood Hits	152	Shared Neighborhood Hits	18
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

N4BP2_HUMAN
NC score	0.020691 (rank : 195)	θ value	1.06291 (rank : 87)
Query Neighborhood Hits	137	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

KR122_HUMAN
NC score	0.016260 (rank : 196)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	137	Target Neighborhood Hits	97	Shared Neighborhood Hits	13
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

ATX2L_HUMAN
NC score	0.014296 (rank : 197)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	137	Target Neighborhood Hits	443	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

EZH2_MOUSE
NC score	0.013251 (rank : 198)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	137	Target Neighborhood Hits	86	Shared Neighborhood Hits	10
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

ATX2L_MOUSE
NC score	0.011845 (rank : 199)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	137	Target Neighborhood Hits	401	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

EZH2_HUMAN
NC score	0.011752 (rank : 200)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	137	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

PCLO_HUMAN
NC score	0.010099 (rank : 201)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	137	Target Neighborhood Hits	2046	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PCLO_MOUSE
NC score	0.009993 (rank : 202)	θ value	1.38821 (rank : 94)
Query Neighborhood Hits	137	Target Neighborhood Hits	2275	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ANX10_MOUSE
NC score	0.006294 (rank : 203)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	137	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZ10	Gene names	Anxa10
Domain Architecture
Description	Annexin A10.

JPH2_MOUSE
NC score	0.003848 (rank : 204)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	137	Target Neighborhood Hits	279	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

VMDL3_MOUSE
NC score	0.003441 (rank : 205)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	137	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q6H1V1	Gene names	Vmd2l3
Domain Architecture	No domain graphic available
Description	Bestrophin-4 (Vitelliform macular dystrophy 2-like protein 3).

UBP47_HUMAN
NC score	0.003339 (rank : 206)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	137	Target Neighborhood Hits	149	Shared Neighborhood Hits	4
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

MILK1_MOUSE
NC score	0.001805 (rank : 207)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	137	Target Neighborhood Hits	788	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

OXRP_HUMAN
NC score	0.001222 (rank : 208)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	137	Target Neighborhood Hits	544	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

WNT4_HUMAN
NC score	0.000868 (rank : 209)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	137	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	P56705, Q5TZQ0, Q96T81, Q9BXF5, Q9H1J8, Q9UJM2	Gene names	WNT4
Domain Architecture
Description	Protein Wnt-4 precursor.

BRWD1_HUMAN
NC score	0.000775 (rank : 210)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	137	Target Neighborhood Hits	448	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

KLH13_HUMAN
NC score	-0.000472 (rank : 211)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	137	Target Neighborhood Hits	193	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2N7, Q6P2E3, Q96QI7, Q9UDN9	Gene names	KLHL13, BKLHD2, KIAA1309
Domain Architecture
Description	Kelch-like protein 13 (BTB and kelch domain-containing protein 2).

KLHL9_MOUSE
NC score	-0.000512 (rank : 212)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	137	Target Neighborhood Hits	195	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPT1	Gene names	Klhl9, Kiaa1354
Domain Architecture	No domain graphic available
Description	Kelch-like protein 9.

CSKI1_HUMAN
NC score	-0.001172 (rank : 213)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	137	Target Neighborhood Hits	997	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ERBB3_MOUSE
NC score	-0.001559 (rank : 214)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	137	Target Neighborhood Hits	898	Shared Neighborhood Hits	16
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

PTN13_HUMAN
NC score	-0.002131 (rank : 215)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	137	Target Neighborhood Hits	471	Shared Neighborhood Hits	4
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PASK_MOUSE
NC score	-0.002261 (rank : 216)	θ value	1.38821 (rank : 93)
Query Neighborhood Hits	137	Target Neighborhood Hits	867	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CEE6, Q91YD8	Gene names	Pask, Kiaa0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN).

ZIC3_MOUSE
NC score	-0.003115 (rank : 217)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	137	Target Neighborhood Hits	713	Shared Neighborhood Hits	5
SwissProt Accessions	Q62521	Gene names	Zic3
Domain Architecture
Description	Zinc finger protein ZIC 3 (Zinc finger protein of the cerebellum 3).

ZIC3_HUMAN
NC score	-0.003121 (rank : 218)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	137	Target Neighborhood Hits	714	Shared Neighborhood Hits	5
SwissProt Accessions	O60481	Gene names	ZIC3
Domain Architecture
Description	Zinc finger protein ZIC 3 (Zinc finger protein of the cerebellum 3).

ZN473_MOUSE
NC score	-0.005729 (rank : 219)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	137	Target Neighborhood Hits	824	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BI67, Q8BI98, Q8BIB7	Gene names	Znf473, Zfp100, Zfp473
Domain Architecture	No domain graphic available
Description	Zinc finger protein 473 homolog (Zinc finger protein 100) (Zfp-100).

TPR_HUMAN
NC score	-0.006023 (rank : 220)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	137	Target Neighborhood Hits	1921	Shared Neighborhood Hits	7
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

M3K6_HUMAN
NC score	-0.006103 (rank : 221)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	137	Target Neighborhood Hits	889	Shared Neighborhood Hits	5
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

M3K12_MOUSE
NC score	-0.006652 (rank : 222)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	137	Target Neighborhood Hits	957	Shared Neighborhood Hits	6
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).