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Network neighborhood for query Sequence : IL4RA_HUMAN

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IL4RA_HUMAN
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IL4RA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	144	Target Neighborhood Hits	144	Shared Neighborhood Hits	144
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

IL4RA_MOUSE
θ value	0 (rank : 2)	NC score	0.897959 (rank : 2)
Query Neighborhood Hits	144	Target Neighborhood Hits	194	Shared Neighborhood Hits	34
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

IL3RB_HUMAN
θ value	6.64225e-11 (rank : 3)	NC score	0.352436 (rank : 4)
Query Neighborhood Hits	144	Target Neighborhood Hits	163	Shared Neighborhood Hits	34
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

IL21R_MOUSE
θ value	5.62301e-10 (rank : 4)	NC score	0.385461 (rank : 3)
Query Neighborhood Hits	144	Target Neighborhood Hits	43	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JHX3, Q9ESM1	Gene names	Il21r, Nilr
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor) (Lymphocyte receptor beta) (LR-beta) (Novel cytokine receptor NR8).

IL21R_HUMAN
θ value	7.59969e-07 (rank : 5)	NC score	0.341110 (rank : 5)
Query Neighborhood Hits	144	Target Neighborhood Hits	53	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HBE5, Q96HZ1, Q9HB91	Gene names	IL21R, NILR
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor).

IL3RB_MOUSE
θ value	1.69304e-06 (rank : 6)	NC score	0.329130 (rank : 6)
Query Neighborhood Hits	144	Target Neighborhood Hits	355	Shared Neighborhood Hits	41
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

NACAM_MOUSE
θ value	0.00102713 (rank : 7)	NC score	0.092053 (rank : 24)
Query Neighborhood Hits	144	Target Neighborhood Hits	1866	Shared Neighborhood Hits	72
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

IL6RB_HUMAN
θ value	0.00509761 (rank : 8)	NC score	0.120650 (rank : 15)
Query Neighborhood Hits	144	Target Neighborhood Hits	181	Shared Neighborhood Hits	27
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

IL3B2_MOUSE
θ value	0.00665767 (rank : 9)	NC score	0.291555 (rank : 7)
Query Neighborhood Hits	144	Target Neighborhood Hits	372	Shared Neighborhood Hits	47
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IL2RG_HUMAN
θ value	0.0252991 (rank : 10)	NC score	0.231556 (rank : 8)
Query Neighborhood Hits	144	Target Neighborhood Hits	34	Shared Neighborhood Hits	13
SwissProt Accessions	P31785	Gene names	IL2RG
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

IL7RA_HUMAN
θ value	0.0431538 (rank : 11)	NC score	0.179344 (rank : 10)
Query Neighborhood Hits	144	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	P16871, Q6SV45, Q9UPC1	Gene names	IL7R
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen) (CDw127).

IL9R_MOUSE
θ value	0.0431538 (rank : 12)	NC score	0.148504 (rank : 11)
Query Neighborhood Hits	144	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	Q01114	Gene names	Il9r
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

OGFR_HUMAN
θ value	0.0563607 (rank : 13)	NC score	0.085343 (rank : 31)
Query Neighborhood Hits	144	Target Neighborhood Hits	1582	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

BAI1_HUMAN
θ value	0.0736092 (rank : 14)	NC score	0.034807 (rank : 91)
Query Neighborhood Hits	144	Target Neighborhood Hits	375	Shared Neighborhood Hits	21
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

NOTC2_MOUSE
θ value	0.0961366 (rank : 15)	NC score	0.019185 (rank : 124)
Query Neighborhood Hits	144	Target Neighborhood Hits	1069	Shared Neighborhood Hits	35
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PCLO_HUMAN
θ value	0.0961366 (rank : 16)	NC score	0.068146 (rank : 43)
Query Neighborhood Hits	144	Target Neighborhood Hits	2046	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

GGA1_MOUSE
θ value	0.125558 (rank : 17)	NC score	0.050662 (rank : 64)
Query Neighborhood Hits	144	Target Neighborhood Hits	128	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

LIFR_HUMAN
θ value	0.125558 (rank : 18)	NC score	0.090468 (rank : 25)
Query Neighborhood Hits	144	Target Neighborhood Hits	130	Shared Neighborhood Hits	16
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

PRP2_MOUSE
θ value	0.125558 (rank : 19)	NC score	0.092990 (rank : 23)
Query Neighborhood Hits	144	Target Neighborhood Hits	347	Shared Neighborhood Hits	31
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

RBP26_HUMAN
θ value	0.163984 (rank : 20)	NC score	0.057914 (rank : 52)
Query Neighborhood Hits	144	Target Neighborhood Hits	146	Shared Neighborhood Hits	6
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

FREA_HUMAN
θ value	0.21417 (rank : 21)	NC score	0.023354 (rank : 120)
Query Neighborhood Hits	144	Target Neighborhood Hits	205	Shared Neighborhood Hits	16
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

LIFR_MOUSE
θ value	0.21417 (rank : 22)	NC score	0.086682 (rank : 29)
Query Neighborhood Hits	144	Target Neighborhood Hits	127	Shared Neighborhood Hits	14
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

IL2RG_MOUSE
θ value	0.279714 (rank : 23)	NC score	0.227020 (rank : 9)
Query Neighborhood Hits	144	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	P34902	Gene names	Il2rg
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

IL6RA_HUMAN
θ value	0.279714 (rank : 24)	NC score	0.088708 (rank : 27)
Query Neighborhood Hits	144	Target Neighborhood Hits	96	Shared Neighborhood Hits	11
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

I13R1_MOUSE
θ value	0.365318 (rank : 25)	NC score	0.126355 (rank : 14)
Query Neighborhood Hits	144	Target Neighborhood Hits	48	Shared Neighborhood Hits	18
SwissProt Accessions	O09030, Q7TT27	Gene names	Il13ra1, Il13r, Il13ra
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (Interleukin-13-binding protein) (NR4) (CD213a1 antigen).

SF01_HUMAN
θ value	0.365318 (rank : 26)	NC score	0.085257 (rank : 32)
Query Neighborhood Hits	144	Target Neighborhood Hits	287	Shared Neighborhood Hits	27
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	0.365318 (rank : 27)	NC score	0.080605 (rank : 33)
Query Neighborhood Hits	144	Target Neighborhood Hits	240	Shared Neighborhood Hits	21
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

TREF1_MOUSE
θ value	0.365318 (rank : 28)	NC score	0.045875 (rank : 69)
Query Neighborhood Hits	144	Target Neighborhood Hits	682	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

MCR_HUMAN
θ value	0.47712 (rank : 29)	NC score	0.026295 (rank : 110)
Query Neighborhood Hits	144	Target Neighborhood Hits	149	Shared Neighborhood Hits	13
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

EPHB2_HUMAN
θ value	0.62314 (rank : 30)	NC score	0.013191 (rank : 147)
Query Neighborhood Hits	144	Target Neighborhood Hits	983	Shared Neighborhood Hits	19
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	0.62314 (rank : 31)	NC score	0.013153 (rank : 148)
Query Neighborhood Hits	144	Target Neighborhood Hits	982	Shared Neighborhood Hits	19
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

IASPP_MOUSE
θ value	0.62314 (rank : 32)	NC score	0.043817 (rank : 75)
Query Neighborhood Hits	144	Target Neighborhood Hits	1024	Shared Neighborhood Hits	47
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PLXB1_HUMAN
θ value	0.62314 (rank : 33)	NC score	0.033990 (rank : 93)
Query Neighborhood Hits	144	Target Neighborhood Hits	360	Shared Neighborhood Hits	29
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

BSN_MOUSE
θ value	0.813845 (rank : 34)	NC score	0.069853 (rank : 41)
Query Neighborhood Hits	144	Target Neighborhood Hits	2057	Shared Neighborhood Hits	76
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DCC_MOUSE
θ value	0.813845 (rank : 35)	NC score	0.032407 (rank : 96)
Query Neighborhood Hits	144	Target Neighborhood Hits	896	Shared Neighborhood Hits	50
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

RFX1_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.039771 (rank : 81)
Query Neighborhood Hits	144	Target Neighborhood Hits	256	Shared Neighborhood Hits	21
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

CITE4_MOUSE
θ value	1.06291 (rank : 37)	NC score	0.055568 (rank : 55)
Query Neighborhood Hits	144	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WUL8, Q66JX0, Q8R176, Q9CZV4	Gene names	Cited4, Mrg2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

EP300_HUMAN
θ value	1.06291 (rank : 38)	NC score	0.055062 (rank : 56)
Query Neighborhood Hits	144	Target Neighborhood Hits	821	Shared Neighborhood Hits	44
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ETV5_MOUSE
θ value	1.06291 (rank : 39)	NC score	0.037586 (rank : 85)
Query Neighborhood Hits	144	Target Neighborhood Hits	328	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

K1802_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.040707 (rank : 79)
Query Neighborhood Hits	144	Target Neighborhood Hits	1378	Shared Neighborhood Hits	52
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LRC41_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.057702 (rank : 53)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q15345, Q71RA8, Q9BSM0	Gene names	LRRC41, MUF1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

LRC41_MOUSE
θ value	1.06291 (rank : 42)	NC score	0.058725 (rank : 49)
Query Neighborhood Hits	144	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K1C9, Q91VX4	Gene names	Lrrc41, Muf1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

RBP2_HUMAN
θ value	1.06291 (rank : 43)	NC score	0.036114 (rank : 87)
Query Neighborhood Hits	144	Target Neighborhood Hits	249	Shared Neighborhood Hits	13
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

TM55B_MOUSE
θ value	1.06291 (rank : 44)	NC score	0.037906 (rank : 84)
Query Neighborhood Hits	144	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q3TWL2	Gene names	Tmem55b
Domain Architecture	No domain graphic available
Description	Transmembrane protein 55B (EC 3.1.3.-) (Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase) (PtdIns-4,5-P2 4-Ptase I).

ZN206_HUMAN
θ value	1.06291 (rank : 45)	NC score	0.001093 (rank : 168)
Query Neighborhood Hits	144	Target Neighborhood Hits	853	Shared Neighborhood Hits	16
SwissProt Accessions	Q96SZ4	Gene names	ZNF206, ZSCAN10
Domain Architecture	No domain graphic available
Description	Zinc finger protein 206 (Zinc finger and SCAN domain-containing protein 10).

GP152_MOUSE
θ value	1.38821 (rank : 46)	NC score	0.025515 (rank : 113)
Query Neighborhood Hits	144	Target Neighborhood Hits	607	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

PRR8_HUMAN
θ value	1.38821 (rank : 47)	NC score	0.058710 (rank : 50)
Query Neighborhood Hits	144	Target Neighborhood Hits	217	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

PTPRD_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.027359 (rank : 108)
Query Neighborhood Hits	144	Target Neighborhood Hits	485	Shared Neighborhood Hits	22
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_MOUSE
θ value	1.38821 (rank : 49)	NC score	0.027596 (rank : 107)
Query Neighborhood Hits	144	Target Neighborhood Hits	491	Shared Neighborhood Hits	22
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

CBP_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.067234 (rank : 44)
Query Neighborhood Hits	144	Target Neighborhood Hits	1051	Shared Neighborhood Hits	61
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

ETV5_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.029394 (rank : 103)
Query Neighborhood Hits	144	Target Neighborhood Hits	181	Shared Neighborhood Hits	22
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

IL5RA_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.088392 (rank : 28)
Query Neighborhood Hits	144	Target Neighborhood Hits	33	Shared Neighborhood Hits	14
SwissProt Accessions	P21183	Gene names	Il5ra, Il5r
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen).

LEPR_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.113268 (rank : 16)
Query Neighborhood Hits	144	Target Neighborhood Hits	112	Shared Neighborhood Hits	21
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

M3K9_HUMAN
θ value	1.81305 (rank : 54)	NC score	0.007135 (rank : 163)
Query Neighborhood Hits	144	Target Neighborhood Hits	1123	Shared Neighborhood Hits	19
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

MLL2_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.044603 (rank : 74)
Query Neighborhood Hits	144	Target Neighborhood Hits	1788	Shared Neighborhood Hits	62
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYOM1_MOUSE
θ value	1.81305 (rank : 56)	NC score	0.034838 (rank : 90)
Query Neighborhood Hits	144	Target Neighborhood Hits	415	Shared Neighborhood Hits	20
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

PLXB1_MOUSE
θ value	1.81305 (rank : 57)	NC score	0.028422 (rank : 105)
Query Neighborhood Hits	144	Target Neighborhood Hits	259	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

ARI1A_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.047817 (rank : 68)
Query Neighborhood Hits	144	Target Neighborhood Hits	787	Shared Neighborhood Hits	46
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

MAP1B_MOUSE
θ value	2.36792 (rank : 59)	NC score	0.024673 (rank : 114)
Query Neighborhood Hits	144	Target Neighborhood Hits	977	Shared Neighborhood Hits	27
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

SON_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.045766 (rank : 70)
Query Neighborhood Hits	144	Target Neighborhood Hits	957	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TREF1_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.039553 (rank : 82)
Query Neighborhood Hits	144	Target Neighborhood Hits	651	Shared Neighborhood Hits	20
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

BRSK1_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.004062 (rank : 166)
Query Neighborhood Hits	144	Target Neighborhood Hits	942	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

CHD9_MOUSE
θ value	3.0926 (rank : 63)	NC score	0.019826 (rank : 123)
Query Neighborhood Hits	144	Target Neighborhood Hits	427	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CNTN1_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.017905 (rank : 128)
Query Neighborhood Hits	144	Target Neighborhood Hits	431	Shared Neighborhood Hits	13
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

CRTC1_MOUSE
θ value	3.0926 (rank : 65)	NC score	0.045297 (rank : 72)
Query Neighborhood Hits	144	Target Neighborhood Hits	230	Shared Neighborhood Hits	27
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

FA47A_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.045044 (rank : 73)
Query Neighborhood Hits	144	Target Neighborhood Hits	451	Shared Neighborhood Hits	32
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FBLI1_MOUSE
θ value	3.0926 (rank : 67)	NC score	0.016948 (rank : 129)
Query Neighborhood Hits	144	Target Neighborhood Hits	228	Shared Neighborhood Hits	11
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

GSCL_MOUSE
θ value	3.0926 (rank : 68)	NC score	0.012233 (rank : 151)
Query Neighborhood Hits	144	Target Neighborhood Hits	339	Shared Neighborhood Hits	8
SwissProt Accessions	P56916	Gene names	Gscl
Domain Architecture	No domain graphic available
Description	Homeobox protein goosecoid-like (GSC-2).

GSCR1_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.075820 (rank : 35)
Query Neighborhood Hits	144	Target Neighborhood Hits	674	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

ITB4_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.026245 (rank : 112)
Query Neighborhood Hits	144	Target Neighborhood Hits	458	Shared Neighborhood Hits	18
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

KCNH2_MOUSE
θ value	3.0926 (rank : 71)	NC score	0.014877 (rank : 143)
Query Neighborhood Hits	144	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

MUCDL_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.037098 (rank : 86)
Query Neighborhood Hits	144	Target Neighborhood Hits	777	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PLEC1_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.004684 (rank : 164)
Query Neighborhood Hits	144	Target Neighborhood Hits	1326	Shared Neighborhood Hits	13
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PRDM2_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.015914 (rank : 138)
Query Neighborhood Hits	144	Target Neighborhood Hits	1135	Shared Neighborhood Hits	30
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

PZRN3_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.010920 (rank : 154)
Query Neighborhood Hits	144	Target Neighborhood Hits	461	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

REL2_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.030128 (rank : 101)
Query Neighborhood Hits	144	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P04090, Q99936, Q9UCX3, Q9UQJ2	Gene names	RLN2
Domain Architecture
Description	Prorelaxin H2 precursor [Contains: Relaxin B chain; Relaxin A chain].

SC24C_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.048417 (rank : 67)
Query Neighborhood Hits	144	Target Neighborhood Hits	662	Shared Neighborhood Hits	48
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SNPC4_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.045541 (rank : 71)
Query Neighborhood Hits	144	Target Neighborhood Hits	589	Shared Neighborhood Hits	39
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SOCS7_MOUSE
θ value	3.0926 (rank : 79)	NC score	0.023990 (rank : 117)
Query Neighborhood Hits	144	Target Neighborhood Hits	154	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

AF17_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.018855 (rank : 126)
Query Neighborhood Hits	144	Target Neighborhood Hits	230	Shared Neighborhood Hits	14
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

BAI1_MOUSE
θ value	4.03905 (rank : 81)	NC score	0.026298 (rank : 109)
Query Neighborhood Hits	144	Target Neighborhood Hits	340	Shared Neighborhood Hits	17
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BBC3_MOUSE
θ value	4.03905 (rank : 82)	NC score	0.033322 (rank : 95)
Query Neighborhood Hits	144	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q99ML1	Gene names	Bbc3, Puma
Domain Architecture	No domain graphic available
Description	Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis).

CO4A1_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.013853 (rank : 144)
Query Neighborhood Hits	144	Target Neighborhood Hits	425	Shared Neighborhood Hits	24
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

DDEF2_MOUSE
θ value	4.03905 (rank : 84)	NC score	0.015911 (rank : 139)
Query Neighborhood Hits	144	Target Neighborhood Hits	625	Shared Neighborhood Hits	18
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

EPN3_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.031799 (rank : 99)
Query Neighborhood Hits	144	Target Neighborhood Hits	197	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

HCN2_MOUSE
θ value	4.03905 (rank : 86)	NC score	0.024349 (rank : 116)
Query Neighborhood Hits	144	Target Neighborhood Hits	278	Shared Neighborhood Hits	21
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HXA3_MOUSE
θ value	4.03905 (rank : 87)	NC score	0.016834 (rank : 131)
Query Neighborhood Hits	144	Target Neighborhood Hits	558	Shared Neighborhood Hits	34
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

MLL4_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.042634 (rank : 77)
Query Neighborhood Hits	144	Target Neighborhood Hits	722	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PELP1_HUMAN
θ value	4.03905 (rank : 89)	NC score	0.039898 (rank : 80)
Query Neighborhood Hits	144	Target Neighborhood Hits	596	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

RBP2_MOUSE
θ value	4.03905 (rank : 90)	NC score	0.031973 (rank : 98)
Query Neighborhood Hits	144	Target Neighborhood Hits	232	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

RXRB_HUMAN
θ value	4.03905 (rank : 91)	NC score	0.018928 (rank : 125)
Query Neighborhood Hits	144	Target Neighborhood Hits	280	Shared Neighborhood Hits	29
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

RXRG_MOUSE
θ value	4.03905 (rank : 92)	NC score	0.012394 (rank : 149)
Query Neighborhood Hits	144	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

SRBP1_MOUSE
θ value	4.03905 (rank : 93)	NC score	0.027624 (rank : 106)
Query Neighborhood Hits	144	Target Neighborhood Hits	384	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TBCD3_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.018013 (rank : 127)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

ARMX5_MOUSE
θ value	5.27518 (rank : 95)	NC score	0.015501 (rank : 141)
Query Neighborhood Hits	144	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UZB0	Gene names	Armcx5
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 5.

BSN_HUMAN
θ value	5.27518 (rank : 96)	NC score	0.058534 (rank : 51)
Query Neighborhood Hits	144	Target Neighborhood Hits	1537	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CHD9_HUMAN
θ value	5.27518 (rank : 97)	NC score	0.016021 (rank : 136)
Query Neighborhood Hits	144	Target Neighborhood Hits	343	Shared Neighborhood Hits	8
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CO4A4_HUMAN
θ value	5.27518 (rank : 98)	NC score	0.016510 (rank : 133)
Query Neighborhood Hits	144	Target Neighborhood Hits	440	Shared Neighborhood Hits	23
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

DDR1_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.007834 (rank : 158)
Query Neighborhood Hits	144	Target Neighborhood Hits	819	Shared Neighborhood Hits	10
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
θ value	5.27518 (rank : 100)	NC score	0.007779 (rank : 159)
Query Neighborhood Hits	144	Target Neighborhood Hits	818	Shared Neighborhood Hits	10
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

K1802_MOUSE
θ value	5.27518 (rank : 101)	NC score	0.048937 (rank : 66)
Query Neighborhood Hits	144	Target Neighborhood Hits	1596	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MUC1_MOUSE
θ value	5.27518 (rank : 102)	NC score	0.035769 (rank : 88)
Query Neighborhood Hits	144	Target Neighborhood Hits	388	Shared Neighborhood Hits	22
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

NCOA6_MOUSE
θ value	5.27518 (rank : 103)	NC score	0.062447 (rank : 47)
Query Neighborhood Hits	144	Target Neighborhood Hits	1076	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PHLPP_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.013315 (rank : 146)
Query Neighborhood Hits	144	Target Neighborhood Hits	604	Shared Neighborhood Hits	25
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PS1C2_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.050233 (rank : 65)
Query Neighborhood Hits	144	Target Neighborhood Hits	59	Shared Neighborhood Hits	9
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

PTN23_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.032013 (rank : 97)
Query Neighborhood Hits	144	Target Neighborhood Hits	726	Shared Neighborhood Hits	45
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SEM5B_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.015933 (rank : 137)
Query Neighborhood Hits	144	Target Neighborhood Hits	190	Shared Neighborhood Hits	9
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SYNJ1_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.035629 (rank : 89)
Query Neighborhood Hits	144	Target Neighborhood Hits	516	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TENX_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.016899 (rank : 130)
Query Neighborhood Hits	144	Target Neighborhood Hits	789	Shared Neighborhood Hits	25
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TROAP_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.053980 (rank : 58)
Query Neighborhood Hits	144	Target Neighborhood Hits	258	Shared Neighborhood Hits	28
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

ADA29_HUMAN
θ value	6.88961 (rank : 111)	NC score	0.008522 (rank : 155)
Query Neighborhood Hits	144	Target Neighborhood Hits	247	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ARI1B_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.041403 (rank : 78)
Query Neighborhood Hits	144	Target Neighborhood Hits	567	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ES8L3_MOUSE
θ value	6.88961 (rank : 113)	NC score	0.011657 (rank : 153)
Query Neighborhood Hits	144	Target Neighborhood Hits	168	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

FRAT1_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.023823 (rank : 118)
Query Neighborhood Hits	144	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	Q92837, Q8NE74, Q8TDW9	Gene names	FRAT1
Domain Architecture
Description	Proto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas) (Frat-1).

GSCL_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.007581 (rank : 160)
Query Neighborhood Hits	144	Target Neighborhood Hits	343	Shared Neighborhood Hits	5
SwissProt Accessions	O15499	Gene names	GSCL
Domain Architecture
Description	Homeobox protein goosecoid-like (GSC-2).

HXA3_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.015645 (rank : 140)
Query Neighborhood Hits	144	Target Neighborhood Hits	535	Shared Neighborhood Hits	28
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

IER5_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.024566 (rank : 115)
Query Neighborhood Hits	144	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q5VY09, Q8WY68, Q9NY49, Q9NZP9	Gene names	IER5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

LAMP1_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.016090 (rank : 134)
Query Neighborhood Hits	144	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P11279	Gene names	LAMP1
Domain Architecture
Description	Lysosome-associated membrane glycoprotein 1 precursor (LAMP-1) (CD107a antigen).

LEPR_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.110881 (rank : 17)
Query Neighborhood Hits	144	Target Neighborhood Hits	109	Shared Neighborhood Hits	20
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

MDC1_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.043718 (rank : 76)
Query Neighborhood Hits	144	Target Neighborhood Hits	1446	Shared Neighborhood Hits	55
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYLK_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.007525 (rank : 162)
Query Neighborhood Hits	144	Target Neighborhood Hits	1328	Shared Neighborhood Hits	25
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NOTC2_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.016055 (rank : 135)
Query Neighborhood Hits	144	Target Neighborhood Hits	1113	Shared Neighborhood Hits	41
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NR4A3_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.012392 (rank : 150)
Query Neighborhood Hits	144	Target Neighborhood Hits	131	Shared Neighborhood Hits	9
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

PDC6I_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.033875 (rank : 94)
Query Neighborhood Hits	144	Target Neighborhood Hits	278	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PTN23_HUMAN
θ value	6.88961 (rank : 125)	NC score	0.029322 (rank : 104)
Query Neighborhood Hits	144	Target Neighborhood Hits	646	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RREB1_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.007839 (rank : 157)
Query Neighborhood Hits	144	Target Neighborhood Hits	879	Shared Neighborhood Hits	19
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

SENP3_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.030345 (rank : 100)
Query Neighborhood Hits	144	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

ADDB_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.011720 (rank : 152)
Query Neighborhood Hits	144	Target Neighborhood Hits	142	Shared Neighborhood Hits	8
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).

ARSD_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.007923 (rank : 156)
Query Neighborhood Hits	144	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P51689, Q9UHJ8	Gene names	ARSD
Domain Architecture
Description	Arylsulfatase D precursor (EC 3.1.6.-) (ASD).

FRAT2_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.023631 (rank : 119)
Query Neighborhood Hits	144	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	O75474, Q5JTI0, Q8WUL9, Q9BYG2	Gene names	FRAT2
Domain Architecture
Description	GSK-3-binding protein FRAT2 (Frat-2).

GGA1_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.029524 (rank : 102)
Query Neighborhood Hits	144	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GRIN1_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.039126 (rank : 83)
Query Neighborhood Hits	144	Target Neighborhood Hits	681	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HCFC2_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.016685 (rank : 132)
Query Neighborhood Hits	144	Target Neighborhood Hits	154	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

IL7RA_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.104287 (rank : 18)
Query Neighborhood Hits	144	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	P16872	Gene names	Il7r
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen).

INSM1_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.004516 (rank : 165)
Query Neighborhood Hits	144	Target Neighborhood Hits	683	Shared Neighborhood Hits	9
SwissProt Accessions	Q01101	Gene names	INSM1, IA1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

IRX6_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.007548 (rank : 161)
Query Neighborhood Hits	144	Target Neighborhood Hits	262	Shared Neighborhood Hits	4
SwissProt Accessions	P78412, Q7Z2K0	Gene names	IRX6, IRX7, IRXB3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-6 (Iroquois homeobox protein 6) (Homeodomain protein IRXB3).

KCC1A_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.001751 (rank : 167)
Query Neighborhood Hits	144	Target Neighborhood Hits	846	Shared Neighborhood Hits	9
SwissProt Accessions	Q14012	Gene names	CAMK1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

MCR_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.019885 (rank : 122)
Query Neighborhood Hits	144	Target Neighborhood Hits	162	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

MUC2_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.034082 (rank : 92)
Query Neighborhood Hits	144	Target Neighborhood Hits	906	Shared Neighborhood Hits	35
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PRP1_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.067109 (rank : 45)
Query Neighborhood Hits	144	Target Neighborhood Hits	385	Shared Neighborhood Hits	35
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

S2A4R_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.020358 (rank : 121)
Query Neighborhood Hits	144	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR83, Q6F6I6, Q6F6I7, Q6GTK5, Q8TAH5, Q8WVW7, Q96QD3, Q9BV85	Gene names	SLC2A4RG, HDBP1
Domain Architecture	No domain graphic available
Description	SLC2A4 regulator (GLUT4 enhancer factor) (GEF) (Huntington disease gene regulatory region-binding protein 1) (HDBP-1).

SEM5B_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.015201 (rank : 142)
Query Neighborhood Hits	144	Target Neighborhood Hits	178	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SENP3_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.026258 (rank : 111)
Query Neighborhood Hits	144	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H4L4, Q96PS4, Q9Y3W9	Gene names	SENP3, SSP3, SUSP3
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3).

SEZ6L_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.013486 (rank : 145)
Query Neighborhood Hits	144	Target Neighborhood Hits	289	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

CBP_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.072579 (rank : 39)
Query Neighborhood Hits	144	Target Neighborhood Hits	941	Shared Neighborhood Hits	55
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CRLF1_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.071078 (rank : 40)
Query Neighborhood Hits	144	Target Neighborhood Hits	122	Shared Neighborhood Hits	23
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

CRLF1_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.069773 (rank : 42)
Query Neighborhood Hits	144	Target Neighborhood Hits	116	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

CRLF2_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.065401 (rank : 46)
Query Neighborhood Hits	144	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HC73, Q9H5R3	Gene names	CRLF2, ILXR
Domain Architecture	No domain graphic available
Description	Cytokine receptor-like factor 2 precursor (Cytokine receptor-like 2) (CRL2) (IL-XR) (Thymic stromal lymphopoietin protein receptor) (TSLPR).

EPOR_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.089168 (rank : 26)
Query Neighborhood Hits	144	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	P19235, Q15443	Gene names	EPOR
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

EPOR_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.093979 (rank : 21)
Query Neighborhood Hits	144	Target Neighborhood Hits	52	Shared Neighborhood Hits	17
SwissProt Accessions	P14753, Q63852	Gene names	Epor
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

I12R2_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.050774 (rank : 63)
Query Neighborhood Hits	144	Target Neighborhood Hits	163	Shared Neighborhood Hits	19
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

I13R1_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.095167 (rank : 20)
Query Neighborhood Hits	144	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	P78552, O95646, Q99656	Gene names	IL13RA1, IL13R, IL13RA
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (CD213a1 antigen).

I13R2_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.093336 (rank : 22)
Query Neighborhood Hits	144	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q14627, O00667	Gene names	IL13RA2, IL13R
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-2 chain precursor (Interleukin-13- binding protein) (CD213a2 antigen).

IL2RB_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.085903 (rank : 30)
Query Neighborhood Hits	144	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	P14784	Gene names	IL2RB
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (p75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

IL2RB_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.134138 (rank : 12)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

IL5RA_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.079442 (rank : 34)
Query Neighborhood Hits	144	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	Q01344, Q6ISX9	Gene names	IL5RA, IL5R
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen) (CDw125).

IL6RA_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.056919 (rank : 54)
Query Neighborhood Hits	144	Target Neighborhood Hits	104	Shared Neighborhood Hits	13
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

IL6RB_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.095942 (rank : 19)
Query Neighborhood Hits	144	Target Neighborhood Hits	168	Shared Neighborhood Hits	27
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

IL9R_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.126539 (rank : 13)
Query Neighborhood Hits	144	Target Neighborhood Hits	35	Shared Neighborhood Hits	13
SwissProt Accessions	Q01113, Q14634, Q8WWU1, Q96TF0	Gene names	IL9R
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

MUC1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.051931 (rank : 62)
Query Neighborhood Hits	144	Target Neighborhood Hits	975	Shared Neighborhood Hits	53
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MUC7_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.058862 (rank : 48)
Query Neighborhood Hits	144	Target Neighborhood Hits	538	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NCOA6_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.053963 (rank : 59)
Query Neighborhood Hits	144	Target Neighborhood Hits	1202	Shared Neighborhood Hits	69
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PCLO_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.054740 (rank : 57)
Query Neighborhood Hits	144	Target Neighborhood Hits	2275	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PRB3_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.074209 (rank : 37)
Query Neighborhood Hits	144	Target Neighborhood Hits	318	Shared Neighborhood Hits	27
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.072639 (rank : 38)
Query Neighborhood Hits	144	Target Neighborhood Hits	330	Shared Neighborhood Hits	26
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

SON_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.052532 (rank : 61)
Query Neighborhood Hits	144	Target Neighborhood Hits	1568	Shared Neighborhood Hits	77
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

T22D2_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.074664 (rank : 36)
Query Neighborhood Hits	144	Target Neighborhood Hits	250	Shared Neighborhood Hits	27
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

WASIP_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.053742 (rank : 60)
Query Neighborhood Hits	144	Target Neighborhood Hits	458	Shared Neighborhood Hits	31
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

Hits sorted by NC score

IL4RA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	144	Target Neighborhood Hits	144	Shared Neighborhood Hits	144
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

IL4RA_MOUSE
NC score	0.897959 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	144	Target Neighborhood Hits	194	Shared Neighborhood Hits	34
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

IL21R_MOUSE
NC score	0.385461 (rank : 3)	θ value	5.62301e-10 (rank : 4)
Query Neighborhood Hits	144	Target Neighborhood Hits	43	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JHX3, Q9ESM1	Gene names	Il21r, Nilr
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor) (Lymphocyte receptor beta) (LR-beta) (Novel cytokine receptor NR8).

IL3RB_HUMAN
NC score	0.352436 (rank : 4)	θ value	6.64225e-11 (rank : 3)
Query Neighborhood Hits	144	Target Neighborhood Hits	163	Shared Neighborhood Hits	34
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

IL21R_HUMAN
NC score	0.341110 (rank : 5)	θ value	7.59969e-07 (rank : 5)
Query Neighborhood Hits	144	Target Neighborhood Hits	53	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HBE5, Q96HZ1, Q9HB91	Gene names	IL21R, NILR
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor).

IL3RB_MOUSE
NC score	0.329130 (rank : 6)	θ value	1.69304e-06 (rank : 6)
Query Neighborhood Hits	144	Target Neighborhood Hits	355	Shared Neighborhood Hits	41
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

IL3B2_MOUSE
NC score	0.291555 (rank : 7)	θ value	0.00665767 (rank : 9)
Query Neighborhood Hits	144	Target Neighborhood Hits	372	Shared Neighborhood Hits	47
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IL2RG_HUMAN
NC score	0.231556 (rank : 8)	θ value	0.0252991 (rank : 10)
Query Neighborhood Hits	144	Target Neighborhood Hits	34	Shared Neighborhood Hits	13
SwissProt Accessions	P31785	Gene names	IL2RG
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

IL2RG_MOUSE
NC score	0.227020 (rank : 9)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	144	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	P34902	Gene names	Il2rg
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

IL7RA_HUMAN
NC score	0.179344 (rank : 10)	θ value	0.0431538 (rank : 11)
Query Neighborhood Hits	144	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	P16871, Q6SV45, Q9UPC1	Gene names	IL7R
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen) (CDw127).

IL9R_MOUSE
NC score	0.148504 (rank : 11)	θ value	0.0431538 (rank : 12)
Query Neighborhood Hits	144	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	Q01114	Gene names	Il9r
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

IL2RB_MOUSE
NC score	0.134138 (rank : 12)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

IL9R_HUMAN
NC score	0.126539 (rank : 13)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	144	Target Neighborhood Hits	35	Shared Neighborhood Hits	13
SwissProt Accessions	Q01113, Q14634, Q8WWU1, Q96TF0	Gene names	IL9R
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

I13R1_MOUSE
NC score	0.126355 (rank : 14)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	144	Target Neighborhood Hits	48	Shared Neighborhood Hits	18
SwissProt Accessions	O09030, Q7TT27	Gene names	Il13ra1, Il13r, Il13ra
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (Interleukin-13-binding protein) (NR4) (CD213a1 antigen).

IL6RB_HUMAN
NC score	0.120650 (rank : 15)	θ value	0.00509761 (rank : 8)
Query Neighborhood Hits	144	Target Neighborhood Hits	181	Shared Neighborhood Hits	27
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

LEPR_HUMAN
NC score	0.113268 (rank : 16)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	144	Target Neighborhood Hits	112	Shared Neighborhood Hits	21
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

LEPR_MOUSE
NC score	0.110881 (rank : 17)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	144	Target Neighborhood Hits	109	Shared Neighborhood Hits	20
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

IL7RA_MOUSE
NC score	0.104287 (rank : 18)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	144	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	P16872	Gene names	Il7r
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen).

IL6RB_MOUSE
NC score	0.095942 (rank : 19)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	144	Target Neighborhood Hits	168	Shared Neighborhood Hits	27
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

I13R1_HUMAN
NC score	0.095167 (rank : 20)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	144	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	P78552, O95646, Q99656	Gene names	IL13RA1, IL13R, IL13RA
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (CD213a1 antigen).

EPOR_MOUSE
NC score	0.093979 (rank : 21)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	144	Target Neighborhood Hits	52	Shared Neighborhood Hits	17
SwissProt Accessions	P14753, Q63852	Gene names	Epor
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

I13R2_HUMAN
NC score	0.093336 (rank : 22)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	144	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q14627, O00667	Gene names	IL13RA2, IL13R
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-2 chain precursor (Interleukin-13- binding protein) (CD213a2 antigen).

PRP2_MOUSE
NC score	0.092990 (rank : 23)	θ value	0.125558 (rank : 19)
Query Neighborhood Hits	144	Target Neighborhood Hits	347	Shared Neighborhood Hits	31
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

NACAM_MOUSE
NC score	0.092053 (rank : 24)	θ value	0.00102713 (rank : 7)
Query Neighborhood Hits	144	Target Neighborhood Hits	1866	Shared Neighborhood Hits	72
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

LIFR_HUMAN
NC score	0.090468 (rank : 25)	θ value	0.125558 (rank : 18)
Query Neighborhood Hits	144	Target Neighborhood Hits	130	Shared Neighborhood Hits	16
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

EPOR_HUMAN
NC score	0.089168 (rank : 26)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	144	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	P19235, Q15443	Gene names	EPOR
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

IL6RA_HUMAN
NC score	0.088708 (rank : 27)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	144	Target Neighborhood Hits	96	Shared Neighborhood Hits	11
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

IL5RA_MOUSE
NC score	0.088392 (rank : 28)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	144	Target Neighborhood Hits	33	Shared Neighborhood Hits	14
SwissProt Accessions	P21183	Gene names	Il5ra, Il5r
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen).

LIFR_MOUSE
NC score	0.086682 (rank : 29)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	144	Target Neighborhood Hits	127	Shared Neighborhood Hits	14
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

IL2RB_HUMAN
NC score	0.085903 (rank : 30)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	144	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	P14784	Gene names	IL2RB
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (p75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

OGFR_HUMAN
NC score	0.085343 (rank : 31)	θ value	0.0563607 (rank : 13)
Query Neighborhood Hits	144	Target Neighborhood Hits	1582	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SF01_HUMAN
NC score	0.085257 (rank : 32)	θ value	0.365318 (rank : 26)
Query Neighborhood Hits	144	Target Neighborhood Hits	287	Shared Neighborhood Hits	27
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
NC score	0.080605 (rank : 33)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	144	Target Neighborhood Hits	240	Shared Neighborhood Hits	21
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

IL5RA_HUMAN
NC score	0.079442 (rank : 34)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	144	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	Q01344, Q6ISX9	Gene names	IL5RA, IL5R
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen) (CDw125).

GSCR1_HUMAN
NC score	0.075820 (rank : 35)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	144	Target Neighborhood Hits	674	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

T22D2_HUMAN
NC score	0.074664 (rank : 36)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	144	Target Neighborhood Hits	250	Shared Neighborhood Hits	27
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

PRB3_HUMAN
NC score	0.074209 (rank : 37)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	144	Target Neighborhood Hits	318	Shared Neighborhood Hits	27
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
NC score	0.072639 (rank : 38)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	144	Target Neighborhood Hits	330	Shared Neighborhood Hits	26
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

CBP_HUMAN
NC score	0.072579 (rank : 39)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	144	Target Neighborhood Hits	941	Shared Neighborhood Hits	55
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CRLF1_HUMAN
NC score	0.071078 (rank : 40)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	144	Target Neighborhood Hits	122	Shared Neighborhood Hits	23
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

BSN_MOUSE
NC score	0.069853 (rank : 41)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	144	Target Neighborhood Hits	2057	Shared Neighborhood Hits	76
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CRLF1_MOUSE
NC score	0.069773 (rank : 42)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	144	Target Neighborhood Hits	116	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

PCLO_HUMAN
NC score	0.068146 (rank : 43)	θ value	0.0961366 (rank : 16)
Query Neighborhood Hits	144	Target Neighborhood Hits	2046	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CBP_MOUSE
NC score	0.067234 (rank : 44)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	144	Target Neighborhood Hits	1051	Shared Neighborhood Hits	61
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PRP1_HUMAN
NC score	0.067109 (rank : 45)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	144	Target Neighborhood Hits	385	Shared Neighborhood Hits	35
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

CRLF2_HUMAN
NC score	0.065401 (rank : 46)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	144	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HC73, Q9H5R3	Gene names	CRLF2, ILXR
Domain Architecture	No domain graphic available
Description	Cytokine receptor-like factor 2 precursor (Cytokine receptor-like 2) (CRL2) (IL-XR) (Thymic stromal lymphopoietin protein receptor) (TSLPR).

NCOA6_MOUSE
NC score	0.062447 (rank : 47)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	144	Target Neighborhood Hits	1076	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

MUC7_HUMAN
NC score	0.058862 (rank : 48)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	144	Target Neighborhood Hits	538	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

LRC41_MOUSE
NC score	0.058725 (rank : 49)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	144	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K1C9, Q91VX4	Gene names	Lrrc41, Muf1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

PRR8_HUMAN
NC score	0.058710 (rank : 50)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	144	Target Neighborhood Hits	217	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

BSN_HUMAN
NC score	0.058534 (rank : 51)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	144	Target Neighborhood Hits	1537	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

RBP26_HUMAN
NC score	0.057914 (rank : 52)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	144	Target Neighborhood Hits	146	Shared Neighborhood Hits	6
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

LRC41_HUMAN
NC score	0.057702 (rank : 53)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q15345, Q71RA8, Q9BSM0	Gene names	LRRC41, MUF1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

IL6RA_MOUSE
NC score	0.056919 (rank : 54)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	144	Target Neighborhood Hits	104	Shared Neighborhood Hits	13
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

CITE4_MOUSE
NC score	0.055568 (rank : 55)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	144	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WUL8, Q66JX0, Q8R176, Q9CZV4	Gene names	Cited4, Mrg2
Domain Architecture	No domain graphic available
Description	Cbp/p300-interacting transactivator 4 (MSG1-related protein 2) (MRG- 2).

EP300_HUMAN
NC score	0.055062 (rank : 56)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	144	Target Neighborhood Hits	821	Shared Neighborhood Hits	44
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

PCLO_MOUSE
NC score	0.054740 (rank : 57)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	144	Target Neighborhood Hits	2275	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TROAP_HUMAN
NC score	0.053980 (rank : 58)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	144	Target Neighborhood Hits	258	Shared Neighborhood Hits	28
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

NCOA6_HUMAN
NC score	0.053963 (rank : 59)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	144	Target Neighborhood Hits	1202	Shared Neighborhood Hits	69
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

WASIP_HUMAN
NC score	0.053742 (rank : 60)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	144	Target Neighborhood Hits	458	Shared Neighborhood Hits	31
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

SON_HUMAN
NC score	0.052532 (rank : 61)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	144	Target Neighborhood Hits	1568	Shared Neighborhood Hits	77
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

MUC1_HUMAN
NC score	0.051931 (rank : 62)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	144	Target Neighborhood Hits	975	Shared Neighborhood Hits	53
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

I12R2_HUMAN
NC score	0.050774 (rank : 63)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	144	Target Neighborhood Hits	163	Shared Neighborhood Hits	19
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

GGA1_MOUSE
NC score	0.050662 (rank : 64)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	144	Target Neighborhood Hits	128	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

PS1C2_MOUSE
NC score	0.050233 (rank : 65)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	144	Target Neighborhood Hits	59	Shared Neighborhood Hits	9
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

K1802_MOUSE
NC score	0.048937 (rank : 66)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	144	Target Neighborhood Hits	1596	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SC24C_HUMAN
NC score	0.048417 (rank : 67)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	144	Target Neighborhood Hits	662	Shared Neighborhood Hits	48
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

ARI1A_HUMAN
NC score	0.047817 (rank : 68)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	144	Target Neighborhood Hits	787	Shared Neighborhood Hits	46
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

TREF1_MOUSE
NC score	0.045875 (rank : 69)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	144	Target Neighborhood Hits	682	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

SON_MOUSE
NC score	0.045766 (rank : 70)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	144	Target Neighborhood Hits	957	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SNPC4_HUMAN
NC score	0.045541 (rank : 71)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	144	Target Neighborhood Hits	589	Shared Neighborhood Hits	39
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

CRTC1_MOUSE
NC score	0.045297 (rank : 72)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	144	Target Neighborhood Hits	230	Shared Neighborhood Hits	27
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

FA47A_HUMAN
NC score	0.045044 (rank : 73)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	144	Target Neighborhood Hits	451	Shared Neighborhood Hits	32
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

MLL2_HUMAN
NC score	0.044603 (rank : 74)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	144	Target Neighborhood Hits	1788	Shared Neighborhood Hits	62
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

IASPP_MOUSE
NC score	0.043817 (rank : 75)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	144	Target Neighborhood Hits	1024	Shared Neighborhood Hits	47
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

MDC1_HUMAN
NC score	0.043718 (rank : 76)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	144	Target Neighborhood Hits	1446	Shared Neighborhood Hits	55
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MLL4_HUMAN
NC score	0.042634 (rank : 77)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	144	Target Neighborhood Hits	722	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

ARI1B_HUMAN
NC score	0.041403 (rank : 78)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	144	Target Neighborhood Hits	567	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

K1802_HUMAN
NC score	0.040707 (rank : 79)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	144	Target Neighborhood Hits	1378	Shared Neighborhood Hits	52
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PELP1_HUMAN
NC score	0.039898 (rank : 80)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	144	Target Neighborhood Hits	596	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

RFX1_HUMAN
NC score	0.039771 (rank : 81)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	144	Target Neighborhood Hits	256	Shared Neighborhood Hits	21
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

TREF1_HUMAN
NC score	0.039553 (rank : 82)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	144	Target Neighborhood Hits	651	Shared Neighborhood Hits	20
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

GRIN1_HUMAN
NC score	0.039126 (rank : 83)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	144	Target Neighborhood Hits	681	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

TM55B_MOUSE
NC score	0.037906 (rank : 84)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	144	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q3TWL2	Gene names	Tmem55b
Domain Architecture	No domain graphic available
Description	Transmembrane protein 55B (EC 3.1.3.-) (Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase) (PtdIns-4,5-P2 4-Ptase I).

ETV5_MOUSE
NC score	0.037586 (rank : 85)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	144	Target Neighborhood Hits	328	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

MUCDL_HUMAN
NC score	0.037098 (rank : 86)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	144	Target Neighborhood Hits	777	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

RBP2_HUMAN
NC score	0.036114 (rank : 87)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	144	Target Neighborhood Hits	249	Shared Neighborhood Hits	13
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

MUC1_MOUSE
NC score	0.035769 (rank : 88)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	144	Target Neighborhood Hits	388	Shared Neighborhood Hits	22
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

SYNJ1_MOUSE
NC score	0.035629 (rank : 89)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	144	Target Neighborhood Hits	516	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

MYOM1_MOUSE
NC score	0.034838 (rank : 90)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	144	Target Neighborhood Hits	415	Shared Neighborhood Hits	20
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

BAI1_HUMAN
NC score	0.034807 (rank : 91)	θ value	0.0736092 (rank : 14)
Query Neighborhood Hits	144	Target Neighborhood Hits	375	Shared Neighborhood Hits	21
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

MUC2_HUMAN
NC score	0.034082 (rank : 92)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	144	Target Neighborhood Hits	906	Shared Neighborhood Hits	35
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PLXB1_HUMAN
NC score	0.033990 (rank : 93)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	144	Target Neighborhood Hits	360	Shared Neighborhood Hits	29
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PDC6I_HUMAN
NC score	0.033875 (rank : 94)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	144	Target Neighborhood Hits	278	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

BBC3_MOUSE
NC score	0.033322 (rank : 95)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	144	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q99ML1	Gene names	Bbc3, Puma
Domain Architecture	No domain graphic available
Description	Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis).

DCC_MOUSE
NC score	0.032407 (rank : 96)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	144	Target Neighborhood Hits	896	Shared Neighborhood Hits	50
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

PTN23_MOUSE
NC score	0.032013 (rank : 97)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	144	Target Neighborhood Hits	726	Shared Neighborhood Hits	45
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RBP2_MOUSE
NC score	0.031973 (rank : 98)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	144	Target Neighborhood Hits	232	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

EPN3_HUMAN
NC score	0.031799 (rank : 99)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	144	Target Neighborhood Hits	197	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

SENP3_MOUSE
NC score	0.030345 (rank : 100)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	144	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

REL2_HUMAN
NC score	0.030128 (rank : 101)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	144	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P04090, Q99936, Q9UCX3, Q9UQJ2	Gene names	RLN2
Domain Architecture
Description	Prorelaxin H2 precursor [Contains: Relaxin B chain; Relaxin A chain].

GGA1_HUMAN
NC score	0.029524 (rank : 102)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	144	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

ETV5_HUMAN
NC score	0.029394 (rank : 103)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	144	Target Neighborhood Hits	181	Shared Neighborhood Hits	22
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

PTN23_HUMAN
NC score	0.029322 (rank : 104)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	144	Target Neighborhood Hits	646	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PLXB1_MOUSE
NC score	0.028422 (rank : 105)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	144	Target Neighborhood Hits	259	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

SRBP1_MOUSE
NC score	0.027624 (rank : 106)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	144	Target Neighborhood Hits	384	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

PTPRD_MOUSE
NC score	0.027596 (rank : 107)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	144	Target Neighborhood Hits	491	Shared Neighborhood Hits	22
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_HUMAN
NC score	0.027359 (rank : 108)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	144	Target Neighborhood Hits	485	Shared Neighborhood Hits	22
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

BAI1_MOUSE
NC score	0.026298 (rank : 109)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	144	Target Neighborhood Hits	340	Shared Neighborhood Hits	17
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

MCR_HUMAN
NC score	0.026295 (rank : 110)	θ value	0.47712 (rank : 29)
Query Neighborhood Hits	144	Target Neighborhood Hits	149	Shared Neighborhood Hits	13
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

SENP3_HUMAN
NC score	0.026258 (rank : 111)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	144	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H4L4, Q96PS4, Q9Y3W9	Gene names	SENP3, SSP3, SUSP3
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3).

ITB4_HUMAN
NC score	0.026245 (rank : 112)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	144	Target Neighborhood Hits	458	Shared Neighborhood Hits	18
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

GP152_MOUSE
NC score	0.025515 (rank : 113)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	144	Target Neighborhood Hits	607	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

MAP1B_MOUSE
NC score	0.024673 (rank : 114)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	144	Target Neighborhood Hits	977	Shared Neighborhood Hits	27
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

IER5_HUMAN
NC score	0.024566 (rank : 115)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	144	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q5VY09, Q8WY68, Q9NY49, Q9NZP9	Gene names	IER5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

HCN2_MOUSE
NC score	0.024349 (rank : 116)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	144	Target Neighborhood Hits	278	Shared Neighborhood Hits	21
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

SOCS7_MOUSE
NC score	0.023990 (rank : 117)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	144	Target Neighborhood Hits	154	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

FRAT1_HUMAN
NC score	0.023823 (rank : 118)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	144	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	Q92837, Q8NE74, Q8TDW9	Gene names	FRAT1
Domain Architecture
Description	Proto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas) (Frat-1).

FRAT2_HUMAN
NC score	0.023631 (rank : 119)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	144	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	O75474, Q5JTI0, Q8WUL9, Q9BYG2	Gene names	FRAT2
Domain Architecture
Description	GSK-3-binding protein FRAT2 (Frat-2).

FREA_HUMAN
NC score	0.023354 (rank : 120)	θ value	0.21417 (rank : 21)
Query Neighborhood Hits	144	Target Neighborhood Hits	205	Shared Neighborhood Hits	16
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

S2A4R_HUMAN
NC score	0.020358 (rank : 121)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	144	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR83, Q6F6I6, Q6F6I7, Q6GTK5, Q8TAH5, Q8WVW7, Q96QD3, Q9BV85	Gene names	SLC2A4RG, HDBP1
Domain Architecture	No domain graphic available
Description	SLC2A4 regulator (GLUT4 enhancer factor) (GEF) (Huntington disease gene regulatory region-binding protein 1) (HDBP-1).

MCR_MOUSE
NC score	0.019885 (rank : 122)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	144	Target Neighborhood Hits	162	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

CHD9_MOUSE
NC score	0.019826 (rank : 123)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	144	Target Neighborhood Hits	427	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

NOTC2_MOUSE
NC score	0.019185 (rank : 124)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	144	Target Neighborhood Hits	1069	Shared Neighborhood Hits	35
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

RXRB_HUMAN
NC score	0.018928 (rank : 125)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	144	Target Neighborhood Hits	280	Shared Neighborhood Hits	29
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

AF17_HUMAN
NC score	0.018855 (rank : 126)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	144	Target Neighborhood Hits	230	Shared Neighborhood Hits	14
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

TBCD3_HUMAN
NC score	0.018013 (rank : 127)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	144	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

CNTN1_HUMAN
NC score	0.017905 (rank : 128)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	144	Target Neighborhood Hits	431	Shared Neighborhood Hits	13
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

FBLI1_MOUSE
NC score	0.016948 (rank : 129)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	144	Target Neighborhood Hits	228	Shared Neighborhood Hits	11
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

TENX_HUMAN
NC score	0.016899 (rank : 130)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	144	Target Neighborhood Hits	789	Shared Neighborhood Hits	25
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

HXA3_MOUSE
NC score	0.016834 (rank : 131)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	144	Target Neighborhood Hits	558	Shared Neighborhood Hits	34
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

HCFC2_HUMAN
NC score	0.016685 (rank : 132)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	144	Target Neighborhood Hits	154	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

CO4A4_HUMAN
NC score	0.016510 (rank : 133)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	144	Target Neighborhood Hits	440	Shared Neighborhood Hits	23
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

LAMP1_HUMAN
NC score	0.016090 (rank : 134)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	144	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P11279	Gene names	LAMP1
Domain Architecture
Description	Lysosome-associated membrane glycoprotein 1 precursor (LAMP-1) (CD107a antigen).

NOTC2_HUMAN
NC score	0.016055 (rank : 135)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	144	Target Neighborhood Hits	1113	Shared Neighborhood Hits	41
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CHD9_HUMAN
NC score	0.016021 (rank : 136)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	144	Target Neighborhood Hits	343	Shared Neighborhood Hits	8
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

SEM5B_MOUSE
NC score	0.015933 (rank : 137)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	144	Target Neighborhood Hits	190	Shared Neighborhood Hits	9
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

PRDM2_HUMAN
NC score	0.015914 (rank : 138)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	144	Target Neighborhood Hits	1135	Shared Neighborhood Hits	30
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

DDEF2_MOUSE
NC score	0.015911 (rank : 139)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	144	Target Neighborhood Hits	625	Shared Neighborhood Hits	18
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

HXA3_HUMAN
NC score	0.015645 (rank : 140)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	144	Target Neighborhood Hits	535	Shared Neighborhood Hits	28
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

ARMX5_MOUSE
NC score	0.015501 (rank : 141)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	144	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UZB0	Gene names	Armcx5
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 5.

SEM5B_HUMAN
NC score	0.015201 (rank : 142)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	144	Target Neighborhood Hits	178	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

KCNH2_MOUSE
NC score	0.014877 (rank : 143)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	144	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

CO4A1_HUMAN
NC score	0.013853 (rank : 144)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	144	Target Neighborhood Hits	425	Shared Neighborhood Hits	24
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

SEZ6L_HUMAN
NC score	0.013486 (rank : 145)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	144	Target Neighborhood Hits	289	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

PHLPP_HUMAN
NC score	0.013315 (rank : 146)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	144	Target Neighborhood Hits	604	Shared Neighborhood Hits	25
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

EPHB2_HUMAN
NC score	0.013191 (rank : 147)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	144	Target Neighborhood Hits	983	Shared Neighborhood Hits	19
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
NC score	0.013153 (rank : 148)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	144	Target Neighborhood Hits	982	Shared Neighborhood Hits	19
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

RXRG_MOUSE
NC score	0.012394 (rank : 149)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	144	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

NR4A3_HUMAN
NC score	0.012392 (rank : 150)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	144	Target Neighborhood Hits	131	Shared Neighborhood Hits	9
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

GSCL_MOUSE
NC score	0.012233 (rank : 151)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	144	Target Neighborhood Hits	339	Shared Neighborhood Hits	8
SwissProt Accessions	P56916	Gene names	Gscl
Domain Architecture	No domain graphic available
Description	Homeobox protein goosecoid-like (GSC-2).

ADDB_HUMAN
NC score	0.011720 (rank : 152)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	144	Target Neighborhood Hits	142	Shared Neighborhood Hits	8
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).

ES8L3_MOUSE
NC score	0.011657 (rank : 153)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	144	Target Neighborhood Hits	168	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WL0, Q3TJ14	Gene names	Eps8l3, Eps8r3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor pathway substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

PZRN3_HUMAN
NC score	0.010920 (rank : 154)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	144	Target Neighborhood Hits	461	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

ADA29_HUMAN
NC score	0.008522 (rank : 155)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	144	Target Neighborhood Hits	247	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ARSD_HUMAN
NC score	0.007923 (rank : 156)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	144	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P51689, Q9UHJ8	Gene names	ARSD
Domain Architecture
Description	Arylsulfatase D precursor (EC 3.1.6.-) (ASD).

RREB1_HUMAN
NC score	0.007839 (rank : 157)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	144	Target Neighborhood Hits	879	Shared Neighborhood Hits	19
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

DDR1_HUMAN
NC score	0.007834 (rank : 158)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	144	Target Neighborhood Hits	819	Shared Neighborhood Hits	10
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
NC score	0.007779 (rank : 159)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	144	Target Neighborhood Hits	818	Shared Neighborhood Hits	10
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

GSCL_HUMAN
NC score	0.007581 (rank : 160)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	144	Target Neighborhood Hits	343	Shared Neighborhood Hits	5
SwissProt Accessions	O15499	Gene names	GSCL
Domain Architecture
Description	Homeobox protein goosecoid-like (GSC-2).

IRX6_HUMAN
NC score	0.007548 (rank : 161)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	144	Target Neighborhood Hits	262	Shared Neighborhood Hits	4
SwissProt Accessions	P78412, Q7Z2K0	Gene names	IRX6, IRX7, IRXB3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-6 (Iroquois homeobox protein 6) (Homeodomain protein IRXB3).

MYLK_HUMAN
NC score	0.007525 (rank : 162)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	144	Target Neighborhood Hits	1328	Shared Neighborhood Hits	25
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

M3K9_HUMAN
NC score	0.007135 (rank : 163)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	144	Target Neighborhood Hits	1123	Shared Neighborhood Hits	19
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

PLEC1_HUMAN
NC score	0.004684 (rank : 164)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	144	Target Neighborhood Hits	1326	Shared Neighborhood Hits	13
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

INSM1_HUMAN
NC score	0.004516 (rank : 165)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	144	Target Neighborhood Hits	683	Shared Neighborhood Hits	9
SwissProt Accessions	Q01101	Gene names	INSM1, IA1
Domain Architecture	No domain graphic available
Description	Insulinoma-associated protein 1 (Zinc finger protein IA-1).

BRSK1_HUMAN
NC score	0.004062 (rank : 166)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	144	Target Neighborhood Hits	942	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

KCC1A_HUMAN
NC score	0.001751 (rank : 167)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	144	Target Neighborhood Hits	846	Shared Neighborhood Hits	9
SwissProt Accessions	Q14012	Gene names	CAMK1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

ZN206_HUMAN
NC score	0.001093 (rank : 168)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	144	Target Neighborhood Hits	853	Shared Neighborhood Hits	16
SwissProt Accessions	Q96SZ4	Gene names	ZNF206, ZSCAN10
Domain Architecture	No domain graphic available
Description	Zinc finger protein 206 (Zinc finger and SCAN domain-containing protein 10).