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Network neighborhood for query Sequence : BBC3_MOUSE

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BBC3_MOUSE
SwissProt Accessions	Q99ML1	Gene names	Bbc3, Puma
Domain Architecture	No domain graphic available
Description	Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BBC3_MOUSE
θ value	4.38363e-63 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	Q99ML1	Gene names	Bbc3, Puma
Domain Architecture	No domain graphic available
Description	Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis).

BBC3_HUMAN
θ value	2.7521e-57 (rank : 2)	NC score	0.975080 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BXH1, O00171, Q96PG9	Gene names	BBC3, PUMA
Domain Architecture	No domain graphic available
Description	Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis) (JFY-1).

CRSP2_HUMAN
θ value	0.00102713 (rank : 3)	NC score	0.212701 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	380	Shared Neighborhood Hits	8
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

DAB2P_MOUSE
θ value	0.0961366 (rank : 4)	NC score	0.082612 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	284	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

CT151_HUMAN
θ value	0.365318 (rank : 5)	NC score	0.085725 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	382	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

HRBL_MOUSE
θ value	0.62314 (rank : 6)	NC score	0.052429 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	269	Shared Neighborhood Hits	5
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

CU030_HUMAN
θ value	0.813845 (rank : 7)	NC score	0.089352 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UFM2	Gene names	C21orf30
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C21orf30.

DAB2P_HUMAN
θ value	1.06291 (rank : 8)	NC score	0.071398 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	303	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

PI5PA_HUMAN
θ value	1.06291 (rank : 9)	NC score	0.038168 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	749	Shared Neighborhood Hits	6
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

DEND_MOUSE
θ value	1.38821 (rank : 10)	NC score	0.053519 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q80TS7	Gene names	Ddn, Kiaa0749
Domain Architecture	No domain graphic available
Description	Dendrin.

DIDO1_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.033942 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	960	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

FOXN3_HUMAN
θ value	1.38821 (rank : 12)	NC score	0.021987 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	121	Shared Neighborhood Hits	2
SwissProt Accessions	O00409, Q96II7, Q9UIE7	Gene names	CHES1, FOXN3
Domain Architecture
Description	Checkpoint suppressor 1 (Forkhead box protein N3).

ULK1_MOUSE
θ value	1.38821 (rank : 13)	NC score	0.008820 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	1214	Shared Neighborhood Hits	10
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

CT165_HUMAN
θ value	3.0926 (rank : 14)	NC score	0.058465 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BR10	Gene names	C20orf165
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf165.

MLL3_HUMAN
θ value	3.0926 (rank : 15)	NC score	0.021026 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	1644	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

IL4RA_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.033322 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	144	Shared Neighborhood Hits	2
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

PINK1_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.025605 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	741	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXM7, Q8N6T9, Q8NBU3, Q96DE4	Gene names	PINK1
Domain Architecture
Description	Serine/threonine-protein kinase PINK1, mitochondrial precursor (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK).

ABRA_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.026520 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N0Z2	Gene names	ABRA
Domain Architecture	No domain graphic available
Description	Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS).

DAB1_MOUSE
θ value	6.88961 (rank : 19)	NC score	0.022411 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	145	Shared Neighborhood Hits	4
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

K1914_HUMAN
θ value	6.88961 (rank : 20)	NC score	0.022915 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	255	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

PRRT3_HUMAN
θ value	6.88961 (rank : 21)	NC score	0.024597 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	998	Shared Neighborhood Hits	8
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

NFM_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.002550 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	1328	Shared Neighborhood Hits	4
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PINK1_MOUSE
θ value	8.99809 (rank : 23)	NC score	0.021800 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	726	Shared Neighborhood Hits	5
SwissProt Accessions	Q99MQ3, Q7TMZ3, Q811I8, Q91XU5	Gene names	Pink1
Domain Architecture
Description	Serine/threonine-protein kinase PINK1, mitochondrial precursor (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK).

Hits sorted by NC score

BBC3_MOUSE
NC score	0.999962 (rank : 1)	θ value	4.38363e-63 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	Q99ML1	Gene names	Bbc3, Puma
Domain Architecture	No domain graphic available
Description	Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis).

BBC3_HUMAN
NC score	0.975080 (rank : 2)	θ value	2.7521e-57 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BXH1, O00171, Q96PG9	Gene names	BBC3, PUMA
Domain Architecture	No domain graphic available
Description	Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis) (JFY-1).

CRSP2_HUMAN
NC score	0.212701 (rank : 3)	θ value	0.00102713 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	380	Shared Neighborhood Hits	8
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CU030_HUMAN
NC score	0.089352 (rank : 4)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UFM2	Gene names	C21orf30
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C21orf30.

CT151_HUMAN
NC score	0.085725 (rank : 5)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	382	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

DAB2P_MOUSE
NC score	0.082612 (rank : 6)	θ value	0.0961366 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	284	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

DAB2P_HUMAN
NC score	0.071398 (rank : 7)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	303	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

CT165_HUMAN
NC score	0.058465 (rank : 8)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BR10	Gene names	C20orf165
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf165.

DEND_MOUSE
NC score	0.053519 (rank : 9)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q80TS7	Gene names	Ddn, Kiaa0749
Domain Architecture	No domain graphic available
Description	Dendrin.

HRBL_MOUSE
NC score	0.052429 (rank : 10)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	269	Shared Neighborhood Hits	5
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

PI5PA_HUMAN
NC score	0.038168 (rank : 11)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	749	Shared Neighborhood Hits	6
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

DIDO1_HUMAN
NC score	0.033942 (rank : 12)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	960	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

IL4RA_HUMAN
NC score	0.033322 (rank : 13)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	144	Shared Neighborhood Hits	2
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

ABRA_HUMAN
NC score	0.026520 (rank : 14)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N0Z2	Gene names	ABRA
Domain Architecture	No domain graphic available
Description	Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS).

PINK1_HUMAN
NC score	0.025605 (rank : 15)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	741	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXM7, Q8N6T9, Q8NBU3, Q96DE4	Gene names	PINK1
Domain Architecture
Description	Serine/threonine-protein kinase PINK1, mitochondrial precursor (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK).

PRRT3_HUMAN
NC score	0.024597 (rank : 16)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	998	Shared Neighborhood Hits	8
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

K1914_HUMAN
NC score	0.022915 (rank : 17)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	255	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N4X5, Q8TB54, Q96PX4, Q96SY5	Gene names	KIAA1914
Domain Architecture	No domain graphic available
Description	Protein KIAA1914.

DAB1_MOUSE
NC score	0.022411 (rank : 18)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	145	Shared Neighborhood Hits	4
SwissProt Accessions	P97318, P97316, P97317	Gene names	Dab1
Domain Architecture
Description	Disabled homolog 1.

FOXN3_HUMAN
NC score	0.021987 (rank : 19)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	121	Shared Neighborhood Hits	2
SwissProt Accessions	O00409, Q96II7, Q9UIE7	Gene names	CHES1, FOXN3
Domain Architecture
Description	Checkpoint suppressor 1 (Forkhead box protein N3).

PINK1_MOUSE
NC score	0.021800 (rank : 20)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	726	Shared Neighborhood Hits	5
SwissProt Accessions	Q99MQ3, Q7TMZ3, Q811I8, Q91XU5	Gene names	Pink1
Domain Architecture
Description	Serine/threonine-protein kinase PINK1, mitochondrial precursor (EC 2.7.11.1) (PTEN-induced putative kinase protein 1) (BRPK).

MLL3_HUMAN
NC score	0.021026 (rank : 21)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	1644	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ULK1_MOUSE
NC score	0.008820 (rank : 22)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	1214	Shared Neighborhood Hits	10
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

NFM_HUMAN
NC score	0.002550 (rank : 23)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	1328	Shared Neighborhood Hits	4
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).