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Network neighborhood for query Sequence : ADDB_HUMAN

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ADDB_HUMAN
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ADDB_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	142	Target Neighborhood Hits	142	Shared Neighborhood Hits	142
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).

ADDB_MOUSE
θ value	0 (rank : 2)	NC score	0.877296 (rank : 6)
Query Neighborhood Hits	142	Target Neighborhood Hits	574	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

ADDG_HUMAN
θ value	0 (rank : 3)	NC score	0.951190 (rank : 3)
Query Neighborhood Hits	142	Target Neighborhood Hits	60	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UEY8, O43243, Q92773, Q9UEY7	Gene names	ADD3, ADDL
Domain Architecture
Description	Gamma-adducin (Adducin-like protein 70).

ADDG_MOUSE
θ value	0 (rank : 4)	NC score	0.955089 (rank : 2)
Query Neighborhood Hits	142	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QYB5, Q9D2M5, Q9QYB6	Gene names	Add3, Addl
Domain Architecture
Description	Gamma-adducin (Adducin-like protein 70).

ADDA_HUMAN
θ value	7.25522e-167 (rank : 5)	NC score	0.937028 (rank : 4)
Query Neighborhood Hits	142	Target Neighborhood Hits	108	Shared Neighborhood Hits	14
SwissProt Accessions	P35611, Q13734, Q14729, Q16156, Q9UJB6	Gene names	ADD1, ADDA
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

ADDA_MOUSE
θ value	3.04821e-165 (rank : 6)	NC score	0.926090 (rank : 5)
Query Neighborhood Hits	142	Target Neighborhood Hits	198	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

TGON2_HUMAN
θ value	3.77169e-06 (rank : 7)	NC score	0.113834 (rank : 10)
Query Neighborhood Hits	142	Target Neighborhood Hits	1037	Shared Neighborhood Hits	59
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

YTDC1_HUMAN
θ value	0.00035302 (rank : 8)	NC score	0.101903 (rank : 11)
Query Neighborhood Hits	142	Target Neighborhood Hits	458	Shared Neighborhood Hits	38
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

TXND2_MOUSE
θ value	0.000461057 (rank : 9)	NC score	0.089756 (rank : 15)
Query Neighborhood Hits	142	Target Neighborhood Hits	828	Shared Neighborhood Hits	60
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

NFH_MOUSE
θ value	0.000602161 (rank : 10)	NC score	0.068623 (rank : 33)
Query Neighborhood Hits	142	Target Neighborhood Hits	2247	Shared Neighborhood Hits	96
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RGS3_MOUSE
θ value	0.00175202 (rank : 11)	NC score	0.049461 (rank : 90)
Query Neighborhood Hits	142	Target Neighborhood Hits	1621	Shared Neighborhood Hits	47
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CD2L1_HUMAN
θ value	0.00228821 (rank : 12)	NC score	0.026351 (rank : 134)
Query Neighborhood Hits	142	Target Neighborhood Hits	1467	Shared Neighborhood Hits	59
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

TP53B_MOUSE
θ value	0.00298849 (rank : 13)	NC score	0.090252 (rank : 14)
Query Neighborhood Hits	142	Target Neighborhood Hits	644	Shared Neighborhood Hits	44
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

GP158_HUMAN
θ value	0.00390308 (rank : 14)	NC score	0.065932 (rank : 36)
Query Neighborhood Hits	142	Target Neighborhood Hits	221	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

CF010_HUMAN
θ value	0.00665767 (rank : 15)	NC score	0.114855 (rank : 9)
Query Neighborhood Hits	142	Target Neighborhood Hits	329	Shared Neighborhood Hits	35
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

KTN1_MOUSE
θ value	0.00665767 (rank : 16)	NC score	0.041591 (rank : 101)
Query Neighborhood Hits	142	Target Neighborhood Hits	1324	Shared Neighborhood Hits	50
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

LRRF1_HUMAN
θ value	0.00869519 (rank : 17)	NC score	0.079389 (rank : 22)
Query Neighborhood Hits	142	Target Neighborhood Hits	625	Shared Neighborhood Hits	42
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

MYLK_HUMAN
θ value	0.00869519 (rank : 18)	NC score	0.014930 (rank : 168)
Query Neighborhood Hits	142	Target Neighborhood Hits	1328	Shared Neighborhood Hits	24
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

SELPL_MOUSE
θ value	0.0148317 (rank : 19)	NC score	0.066339 (rank : 35)
Query Neighborhood Hits	142	Target Neighborhood Hits	588	Shared Neighborhood Hits	31
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SNUT3_MOUSE
θ value	0.0148317 (rank : 20)	NC score	0.166648 (rank : 7)
Query Neighborhood Hits	142	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K194, Q8BRA8, Q9CSV0	Gene names
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 3.

LIMA1_MOUSE
θ value	0.0252991 (rank : 21)	NC score	0.060241 (rank : 52)
Query Neighborhood Hits	142	Target Neighborhood Hits	298	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

AN30A_HUMAN
θ value	0.0330416 (rank : 22)	NC score	0.037342 (rank : 107)
Query Neighborhood Hits	142	Target Neighborhood Hits	1119	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

MUC1_MOUSE
θ value	0.0330416 (rank : 23)	NC score	0.069544 (rank : 32)
Query Neighborhood Hits	142	Target Neighborhood Hits	388	Shared Neighborhood Hits	24
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

PALM_MOUSE
θ value	0.0431538 (rank : 24)	NC score	0.058990 (rank : 60)
Query Neighborhood Hits	142	Target Neighborhood Hits	228	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

CJ047_MOUSE
θ value	0.0736092 (rank : 25)	NC score	0.060603 (rank : 50)
Query Neighborhood Hits	142	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

TP53B_HUMAN
θ value	0.0736092 (rank : 26)	NC score	0.084723 (rank : 18)
Query Neighborhood Hits	142	Target Neighborhood Hits	413	Shared Neighborhood Hits	43
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

EMSY_HUMAN
θ value	0.125558 (rank : 27)	NC score	0.056207 (rank : 65)
Query Neighborhood Hits	142	Target Neighborhood Hits	296	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

SNUT3_HUMAN
θ value	0.125558 (rank : 28)	NC score	0.137294 (rank : 8)
Query Neighborhood Hits	142	Target Neighborhood Hits	52	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WVK2, Q15410	Gene names
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 3 (U4/U6.U5 tri-snRNP-associated 27 kDa protein) (27K) (Nucleic acid-binding protein RY-1).

BCL6_HUMAN
θ value	0.21417 (rank : 29)	NC score	0.003799 (rank : 190)
Query Neighborhood Hits	142	Target Neighborhood Hits	922	Shared Neighborhood Hits	16
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

NALP5_MOUSE
θ value	0.21417 (rank : 30)	NC score	0.030458 (rank : 119)
Query Neighborhood Hits	142	Target Neighborhood Hits	560	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

RBBP6_MOUSE
θ value	0.21417 (rank : 31)	NC score	0.099325 (rank : 12)
Query Neighborhood Hits	142	Target Neighborhood Hits	1014	Shared Neighborhood Hits	64
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SLK_MOUSE
θ value	0.21417 (rank : 32)	NC score	0.019336 (rank : 156)
Query Neighborhood Hits	142	Target Neighborhood Hits	1798	Shared Neighborhood Hits	60
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TRI44_HUMAN
θ value	0.21417 (rank : 33)	NC score	0.055776 (rank : 66)
Query Neighborhood Hits	142	Target Neighborhood Hits	393	Shared Neighborhood Hits	31
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

NOC3L_HUMAN
θ value	0.279714 (rank : 34)	NC score	0.057874 (rank : 62)
Query Neighborhood Hits	142	Target Neighborhood Hits	135	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WTT2, Q9H5M6, Q9H9D8	Gene names	NOC3L, AD24, C10orf117, FAD24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

ZCPW1_HUMAN
θ value	0.279714 (rank : 35)	NC score	0.040109 (rank : 105)
Query Neighborhood Hits	142	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

SRBS1_MOUSE
θ value	0.365318 (rank : 36)	NC score	0.024114 (rank : 145)
Query Neighborhood Hits	142	Target Neighborhood Hits	409	Shared Neighborhood Hits	13
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

HRH1_MOUSE
θ value	0.47712 (rank : 37)	NC score	0.004224 (rank : 188)
Query Neighborhood Hits	142	Target Neighborhood Hits	896	Shared Neighborhood Hits	4
SwissProt Accessions	P70174, Q91V75, Q91XN0, Q91XN1, Q91XN2, Q91XN3	Gene names	Hrh1, Bphs
Domain Architecture
Description	Histamine H1 receptor.

KMHN1_HUMAN
θ value	0.47712 (rank : 38)	NC score	0.033599 (rank : 113)
Query Neighborhood Hits	142	Target Neighborhood Hits	950	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

LUZP1_MOUSE
θ value	0.47712 (rank : 39)	NC score	0.037032 (rank : 108)
Query Neighborhood Hits	142	Target Neighborhood Hits	940	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MY18A_HUMAN
θ value	0.47712 (rank : 40)	NC score	0.030190 (rank : 120)
Query Neighborhood Hits	142	Target Neighborhood Hits	1929	Shared Neighborhood Hits	64
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SLK_HUMAN
θ value	0.47712 (rank : 41)	NC score	0.018012 (rank : 159)
Query Neighborhood Hits	142	Target Neighborhood Hits	1775	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

TITIN_HUMAN
θ value	0.47712 (rank : 42)	NC score	0.026072 (rank : 135)
Query Neighborhood Hits	142	Target Neighborhood Hits	2923	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

BCAS1_MOUSE
θ value	0.62314 (rank : 43)	NC score	0.044615 (rank : 98)
Query Neighborhood Hits	142	Target Neighborhood Hits	215	Shared Neighborhood Hits	18
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

G3BP2_HUMAN
θ value	0.62314 (rank : 44)	NC score	0.057895 (rank : 61)
Query Neighborhood Hits	142	Target Neighborhood Hits	260	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UN86, O60606, O75149, Q9UPA1	Gene names	G3BP2, KIAA0660
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

MYH11_MOUSE
θ value	0.813845 (rank : 45)	NC score	0.028045 (rank : 125)
Query Neighborhood Hits	142	Target Neighborhood Hits	1777	Shared Neighborhood Hits	69
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

RBBP6_HUMAN
θ value	0.813845 (rank : 46)	NC score	0.073050 (rank : 30)
Query Neighborhood Hits	142	Target Neighborhood Hits	1135	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SIA7A_HUMAN
θ value	0.813845 (rank : 47)	NC score	0.025573 (rank : 136)
Query Neighborhood Hits	142	Target Neighborhood Hits	177	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

ANK2_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.034695 (rank : 111)
Query Neighborhood Hits	142	Target Neighborhood Hits	1615	Shared Neighborhood Hits	63
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CAC1C_HUMAN
θ value	1.06291 (rank : 49)	NC score	0.013852 (rank : 170)
Query Neighborhood Hits	142	Target Neighborhood Hits	158	Shared Neighborhood Hits	10
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

MYH11_HUMAN
θ value	1.06291 (rank : 50)	NC score	0.026966 (rank : 130)
Query Neighborhood Hits	142	Target Neighborhood Hits	1806	Shared Neighborhood Hits	68
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_MOUSE
θ value	1.06291 (rank : 51)	NC score	0.026401 (rank : 133)
Query Neighborhood Hits	142	Target Neighborhood Hits	1829	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYST3_HUMAN
θ value	1.06291 (rank : 52)	NC score	0.050744 (rank : 83)
Query Neighborhood Hits	142	Target Neighborhood Hits	772	Shared Neighborhood Hits	60
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NACAM_MOUSE
θ value	1.06291 (rank : 53)	NC score	0.056484 (rank : 64)
Query Neighborhood Hits	142	Target Neighborhood Hits	1866	Shared Neighborhood Hits	55
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NOC3L_MOUSE
θ value	1.06291 (rank : 54)	NC score	0.041422 (rank : 102)
Query Neighborhood Hits	142	Target Neighborhood Hits	177	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VI84, Q9JKM3	Gene names	Noc3l, Ad24, Fad24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

TTBK1_HUMAN
θ value	1.06291 (rank : 55)	NC score	0.027022 (rank : 129)
Query Neighborhood Hits	142	Target Neighborhood Hits	1058	Shared Neighborhood Hits	37
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

ZEP1_HUMAN
θ value	1.06291 (rank : 56)	NC score	0.014456 (rank : 169)
Query Neighborhood Hits	142	Target Neighborhood Hits	1036	Shared Neighborhood Hits	17
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

COPA_HUMAN
θ value	1.38821 (rank : 57)	NC score	0.008904 (rank : 181)
Query Neighborhood Hits	142	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	P53621	Gene names	COPA
Domain Architecture
Description	Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEPCOP) (HEP- COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin].

GCC2_HUMAN
θ value	1.38821 (rank : 58)	NC score	0.031286 (rank : 118)
Query Neighborhood Hits	142	Target Neighborhood Hits	1558	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

LIRB3_HUMAN
θ value	1.38821 (rank : 59)	NC score	0.008930 (rank : 180)
Query Neighborhood Hits	142	Target Neighborhood Hits	125	Shared Neighborhood Hits	6
SwissProt Accessions	O75022, O15471, Q86U49	Gene names	LILRB3, ILT5, LIR3
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor (Leukocyte immunoglobulin-like receptor 3) (LIR-3) (Immunoglobulin- like transcript 5) (ILT-5) (Monocyte inhibitory receptor HL9) (CD85a antigen).

MAP4_MOUSE
θ value	1.38821 (rank : 60)	NC score	0.049113 (rank : 91)
Query Neighborhood Hits	142	Target Neighborhood Hits	409	Shared Neighborhood Hits	29
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

RBP24_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.031289 (rank : 117)
Query Neighborhood Hits	142	Target Neighborhood Hits	1559	Shared Neighborhood Hits	52
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

SART3_MOUSE
θ value	1.38821 (rank : 62)	NC score	0.020618 (rank : 155)
Query Neighborhood Hits	142	Target Neighborhood Hits	341	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JLI8, Q6ZQI2, Q8BPK9, Q8C3B7, Q8CFU9	Gene names	Sart3, Kiaa0156
Domain Architecture	No domain graphic available
Description	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (mSART-3) (Tumor-rejection antigen SART3).

VEZA_HUMAN
θ value	1.38821 (rank : 63)	NC score	0.048819 (rank : 93)
Query Neighborhood Hits	142	Target Neighborhood Hits	107	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HBM0, Q9H2F4, Q9H2U5, Q9NT70, Q9NVW0, Q9UF91	Gene names	VEZT
Domain Architecture	No domain graphic available
Description	Vezatin.

WAPL_MOUSE
θ value	1.38821 (rank : 64)	NC score	0.032400 (rank : 116)
Query Neighborhood Hits	142	Target Neighborhood Hits	158	Shared Neighborhood Hits	20
SwissProt Accessions	Q65Z40, Q6ZQE9	Gene names	Wapal, Kiaa0261, Wapl
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2).

ABCF1_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.027724 (rank : 128)
Query Neighborhood Hits	142	Target Neighborhood Hits	343	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

BRCA2_MOUSE
θ value	1.81305 (rank : 66)	NC score	0.024414 (rank : 143)
Query Neighborhood Hits	142	Target Neighborhood Hits	222	Shared Neighborhood Hits	18
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

DMP1_MOUSE
θ value	1.81305 (rank : 67)	NC score	0.075712 (rank : 26)
Query Neighborhood Hits	142	Target Neighborhood Hits	498	Shared Neighborhood Hits	48
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

EVI1_MOUSE
θ value	1.81305 (rank : 68)	NC score	0.001382 (rank : 193)
Query Neighborhood Hits	142	Target Neighborhood Hits	826	Shared Neighborhood Hits	11
SwissProt Accessions	P14404	Gene names	Evi1, Evi-1
Domain Architecture	No domain graphic available
Description	Ecotropic virus integration 1 site protein.

MAP1B_MOUSE
θ value	1.81305 (rank : 69)	NC score	0.077906 (rank : 23)
Query Neighborhood Hits	142	Target Neighborhood Hits	977	Shared Neighborhood Hits	68
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MYRIP_HUMAN
θ value	1.81305 (rank : 70)	NC score	0.023915 (rank : 146)
Query Neighborhood Hits	142	Target Neighborhood Hits	269	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

UBP1_HUMAN
θ value	1.81305 (rank : 71)	NC score	0.024538 (rank : 142)
Query Neighborhood Hits	142	Target Neighborhood Hits	259	Shared Neighborhood Hits	23
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

CTDP1_HUMAN
θ value	2.36792 (rank : 72)	NC score	0.045483 (rank : 97)
Query Neighborhood Hits	142	Target Neighborhood Hits	416	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DDX46_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.014991 (rank : 167)
Query Neighborhood Hits	142	Target Neighborhood Hits	357	Shared Neighborhood Hits	26
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

HELZ_HUMAN
θ value	2.36792 (rank : 74)	NC score	0.022023 (rank : 153)
Query Neighborhood Hits	142	Target Neighborhood Hits	198	Shared Neighborhood Hits	7
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

KI21A_MOUSE
θ value	2.36792 (rank : 75)	NC score	0.018205 (rank : 158)
Query Neighborhood Hits	142	Target Neighborhood Hits	1317	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

PEPL_HUMAN
θ value	2.36792 (rank : 76)	NC score	0.025406 (rank : 138)
Query Neighborhood Hits	142	Target Neighborhood Hits	1141	Shared Neighborhood Hits	42
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

TRHY_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.032572 (rank : 115)
Query Neighborhood Hits	142	Target Neighborhood Hits	1385	Shared Neighborhood Hits	48
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TRI44_MOUSE
θ value	2.36792 (rank : 78)	NC score	0.046755 (rank : 95)
Query Neighborhood Hits	142	Target Neighborhood Hits	327	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

CCAR1_MOUSE
θ value	3.0926 (rank : 79)	NC score	0.040382 (rank : 104)
Query Neighborhood Hits	142	Target Neighborhood Hits	414	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

CE290_HUMAN
θ value	3.0926 (rank : 80)	NC score	0.030151 (rank : 121)
Query Neighborhood Hits	142	Target Neighborhood Hits	1553	Shared Neighborhood Hits	52
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CEP35_HUMAN
θ value	3.0926 (rank : 81)	NC score	0.048934 (rank : 92)
Query Neighborhood Hits	142	Target Neighborhood Hits	811	Shared Neighborhood Hits	53
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

INVO_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.039445 (rank : 106)
Query Neighborhood Hits	142	Target Neighborhood Hits	474	Shared Neighborhood Hits	28
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

MDC1_MOUSE
θ value	3.0926 (rank : 83)	NC score	0.063123 (rank : 44)
Query Neighborhood Hits	142	Target Neighborhood Hits	998	Shared Neighborhood Hits	48
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

OGFR_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.035893 (rank : 109)
Query Neighborhood Hits	142	Target Neighborhood Hits	1582	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PP4R1_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.017177 (rank : 161)
Query Neighborhood Hits	142	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

TCF8_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.009710 (rank : 178)
Query Neighborhood Hits	142	Target Neighborhood Hits	1057	Shared Neighborhood Hits	31
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

TIP60_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.027975 (rank : 126)
Query Neighborhood Hits	142	Target Neighborhood Hits	90	Shared Neighborhood Hits	12
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

TIP60_MOUSE
θ value	3.0926 (rank : 88)	NC score	0.028591 (rank : 123)
Query Neighborhood Hits	142	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

BPAEA_MOUSE
θ value	4.03905 (rank : 89)	NC score	0.023146 (rank : 149)
Query Neighborhood Hits	142	Target Neighborhood Hits	1480	Shared Neighborhood Hits	50
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CE110_MOUSE
θ value	4.03905 (rank : 90)	NC score	0.016946 (rank : 162)
Query Neighborhood Hits	142	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TSH4, Q6A072	Gene names	Cep110, Cp110, Kiaa0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

CGRE1_MOUSE
θ value	4.03905 (rank : 91)	NC score	0.027880 (rank : 127)
Query Neighborhood Hits	142	Target Neighborhood Hits	173	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R1U2, Q9D1K1	Gene names	Cgref1, Cgr11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CPLX4_HUMAN
θ value	4.03905 (rank : 92)	NC score	0.023454 (rank : 148)
Query Neighborhood Hits	142	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z7G2	Gene names	CPLX4
Domain Architecture	No domain graphic available
Description	Complexin-4 (Complexin IV) (CPX IV).

CSPG2_MOUSE
θ value	4.03905 (rank : 93)	NC score	0.006504 (rank : 184)
Query Neighborhood Hits	142	Target Neighborhood Hits	711	Shared Neighborhood Hits	20
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CYLC1_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.074307 (rank : 28)
Query Neighborhood Hits	142	Target Neighborhood Hits	408	Shared Neighborhood Hits	33
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

EVL_MOUSE
θ value	4.03905 (rank : 95)	NC score	0.017323 (rank : 160)
Query Neighborhood Hits	142	Target Neighborhood Hits	203	Shared Neighborhood Hits	12
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

NEB1_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.026803 (rank : 131)
Query Neighborhood Hits	142	Target Neighborhood Hits	829	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

SYTL2_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.021852 (rank : 154)
Query Neighborhood Hits	142	Target Neighborhood Hits	248	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

TBC10_MOUSE
θ value	4.03905 (rank : 98)	NC score	0.016722 (rank : 163)
Query Neighborhood Hits	142	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

TRPS1_MOUSE
θ value	4.03905 (rank : 99)	NC score	0.012865 (rank : 171)
Query Neighborhood Hits	142	Target Neighborhood Hits	609	Shared Neighborhood Hits	16
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

CAMKV_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.007159 (rank : 183)
Query Neighborhood Hits	142	Target Neighborhood Hits	1084	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CCD45_MOUSE
θ value	5.27518 (rank : 101)	NC score	0.024571 (rank : 141)
Query Neighborhood Hits	142	Target Neighborhood Hits	663	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CPLX4_MOUSE
θ value	5.27518 (rank : 102)	NC score	0.022474 (rank : 150)
Query Neighborhood Hits	142	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q80WM3, Q8C8Y0, Q91WE5	Gene names	Cplx4
Domain Architecture	No domain graphic available
Description	Complexin-4 (Complexin IV) (CPX IV).

ERCC5_MOUSE
θ value	5.27518 (rank : 103)	NC score	0.022384 (rank : 151)
Query Neighborhood Hits	142	Target Neighborhood Hits	206	Shared Neighborhood Hits	21
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

GP179_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.040574 (rank : 103)
Query Neighborhood Hits	142	Target Neighborhood Hits	372	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

ICB1_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.015038 (rank : 166)
Query Neighborhood Hits	142	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

LATS1_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.005808 (rank : 186)
Query Neighborhood Hits	142	Target Neighborhood Hits	1057	Shared Neighborhood Hits	26
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

NF2L2_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.011775 (rank : 174)
Query Neighborhood Hits	142	Target Neighborhood Hits	183	Shared Neighborhood Hits	12
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

PB1_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.012739 (rank : 172)
Query Neighborhood Hits	142	Target Neighborhood Hits	261	Shared Neighborhood Hits	7
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PLK3_MOUSE
θ value	5.27518 (rank : 109)	NC score	0.003974 (rank : 189)
Query Neighborhood Hits	142	Target Neighborhood Hits	863	Shared Neighborhood Hits	10
SwissProt Accessions	Q60806, Q60822, Q9R009	Gene names	Plk3, Cnk, Fnk
Domain Architecture
Description	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF- inducible kinase).

REST_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.024578 (rank : 140)
Query Neighborhood Hits	142	Target Neighborhood Hits	1506	Shared Neighborhood Hits	50
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SEPT9_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.015992 (rank : 164)
Query Neighborhood Hits	142	Target Neighborhood Hits	706	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SETBP_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.023677 (rank : 147)
Query Neighborhood Hits	142	Target Neighborhood Hits	305	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SIA7A_MOUSE
θ value	5.27518 (rank : 113)	NC score	0.028161 (rank : 124)
Query Neighborhood Hits	142	Target Neighborhood Hits	203	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QZ39, Q9JJP5	Gene names	St6galnac1, Siat7a
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

ZBT40_HUMAN
θ value	5.27518 (rank : 114)	NC score	0.000392 (rank : 194)
Query Neighborhood Hits	142	Target Neighborhood Hits	949	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

ANLN_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.022267 (rank : 152)
Query Neighborhood Hits	142	Target Neighborhood Hits	222	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

CCD19_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.035304 (rank : 110)
Query Neighborhood Hits	142	Target Neighborhood Hits	639	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

DEN4C_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.009756 (rank : 177)
Query Neighborhood Hits	142	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VZ89, Q6AI48, Q6ZUB3, Q8NCY7, Q9H6N4, Q9NUT1, Q9NWA5	Gene names	DENND4C, C9orf55
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 4C.

GLU2B_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.074506 (rank : 27)
Query Neighborhood Hits	142	Target Neighborhood Hits	377	Shared Neighborhood Hits	28
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

LGR6_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.001392 (rank : 192)
Query Neighborhood Hits	142	Target Neighborhood Hits	344	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBX8, Q5T509, Q5T512, Q6UY15, Q86VU0, Q96K69, Q9BYD7	Gene names	LGR6
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 6 (VTS20631).

LMAN1_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.008999 (rank : 179)
Query Neighborhood Hits	142	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	P49257, Q12895, Q8N5I7, Q9UQG1, Q9UQG2, Q9UQG3, Q9UQG4, Q9UQG5, Q9UQG6, Q9UQG7, Q9UQG8, Q9UQG9, Q9UQH0, Q9UQH1, Q9UQH2	Gene names	LMAN1, ERGIC53, F5F8D
Domain Architecture
Description	ERGIC-53 protein precursor (ER-Golgi intermediate compartment 53 kDa protein) (Lectin, mannose-binding 1) (Gp58) (Intracellular mannose- specific lectin MR60).

MDC1_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.047278 (rank : 94)
Query Neighborhood Hits	142	Target Neighborhood Hits	1446	Shared Neighborhood Hits	65
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYH1_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.025527 (rank : 137)
Query Neighborhood Hits	142	Target Neighborhood Hits	1478	Shared Neighborhood Hits	53
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH4_MOUSE
θ value	6.88961 (rank : 123)	NC score	0.024355 (rank : 144)
Query Neighborhood Hits	142	Target Neighborhood Hits	1476	Shared Neighborhood Hits	53
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

PPIG_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.034061 (rank : 112)
Query Neighborhood Hits	142	Target Neighborhood Hits	670	Shared Neighborhood Hits	54
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

REST_HUMAN
θ value	6.88961 (rank : 125)	NC score	0.026579 (rank : 132)
Query Neighborhood Hits	142	Target Neighborhood Hits	1605	Shared Neighborhood Hits	62
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SART3_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.015253 (rank : 165)
Query Neighborhood Hits	142	Target Neighborhood Hits	301	Shared Neighborhood Hits	11
SwissProt Accessions	Q15020, Q58F06, Q8IUS1, Q96J95	Gene names	SART3, KIAA0156, TIP110
Domain Architecture	No domain graphic available
Description	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (hSART-3) (Tat-interacting protein of 110 kDa) (Tip110).

ZN174_HUMAN
θ value	6.88961 (rank : 127)	NC score	-0.000196 (rank : 195)
Query Neighborhood Hits	142	Target Neighborhood Hits	744	Shared Neighborhood Hits	9
SwissProt Accessions	Q15697, Q9BQ34	Gene names	ZNF174, ZSCAN8
Domain Architecture
Description	Zinc finger protein 174 (AW-1) (Zinc finger and SCAN domain-containing protein 8).

DDX46_MOUSE
θ value	8.99809 (rank : 128)	NC score	0.010356 (rank : 176)
Query Neighborhood Hits	142	Target Neighborhood Hits	358	Shared Neighborhood Hits	24
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

G3BP2_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.043088 (rank : 99)
Query Neighborhood Hits	142	Target Neighborhood Hits	258	Shared Neighborhood Hits	13
SwissProt Accessions	P97379, Q9R1B8	Gene names	G3bp2
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

IL4RA_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.011720 (rank : 175)
Query Neighborhood Hits	142	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

LPIN2_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.012638 (rank : 173)
Query Neighborhood Hits	142	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

MAP2_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.028792 (rank : 122)
Query Neighborhood Hits	142	Target Neighborhood Hits	342	Shared Neighborhood Hits	37
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

MYH8_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.024764 (rank : 139)
Query Neighborhood Hits	142	Target Neighborhood Hits	1610	Shared Neighborhood Hits	55
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYST3_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.046485 (rank : 96)
Query Neighborhood Hits	142	Target Neighborhood Hits	688	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NFM_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.041677 (rank : 100)
Query Neighborhood Hits	142	Target Neighborhood Hits	1328	Shared Neighborhood Hits	71
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

PCDLK_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.002112 (rank : 191)
Query Neighborhood Hits	142	Target Neighborhood Hits	172	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYE9, Q9NXP8	Gene names	PCLKC
Domain Architecture	No domain graphic available
Description	Protocadherin LKC precursor (PC-LKC).

RP1L1_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.059474 (rank : 57)
Query Neighborhood Hits	142	Target Neighborhood Hits	1072	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SIPA1_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.006405 (rank : 185)
Query Neighborhood Hits	142	Target Neighborhood Hits	158	Shared Neighborhood Hits	12
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

TARA_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.033182 (rank : 114)
Query Neighborhood Hits	142	Target Neighborhood Hits	1626	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TBX2_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.007581 (rank : 182)
Query Neighborhood Hits	142	Target Neighborhood Hits	195	Shared Neighborhood Hits	10
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TOP2B_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.018629 (rank : 157)
Query Neighborhood Hits	142	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q64511, Q7TQG4	Gene names	Top2b
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

WWP2_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.005623 (rank : 187)
Query Neighborhood Hits	142	Target Neighborhood Hits	177	Shared Neighborhood Hits	13
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

ABTAP_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.050599 (rank : 85)
Query Neighborhood Hits	142	Target Neighborhood Hits	381	Shared Neighborhood Hits	37
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

ACINU_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.050281 (rank : 87)
Query Neighborhood Hits	142	Target Neighborhood Hits	828	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACINU_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.050120 (rank : 89)
Query Neighborhood Hits	142	Target Neighborhood Hits	712	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AFF1_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.060222 (rank : 53)
Query Neighborhood Hits	142	Target Neighborhood Hits	506	Shared Neighborhood Hits	36
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AKA12_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.062758 (rank : 45)
Query Neighborhood Hits	142	Target Neighborhood Hits	825	Shared Neighborhood Hits	60
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

BASP_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.081580 (rank : 21)
Query Neighborhood Hits	142	Target Neighborhood Hits	321	Shared Neighborhood Hits	34
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.067854 (rank : 34)
Query Neighborhood Hits	142	Target Neighborhood Hits	260	Shared Neighborhood Hits	30
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CN155_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.051418 (rank : 81)
Query Neighborhood Hits	142	Target Neighborhood Hits	385	Shared Neighborhood Hits	30
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

DEK_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.064751 (rank : 40)
Query Neighborhood Hits	142	Target Neighborhood Hits	280	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

DMP1_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.062266 (rank : 46)
Query Neighborhood Hits	142	Target Neighborhood Hits	491	Shared Neighborhood Hits	36
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DNMT1_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.050153 (rank : 88)
Query Neighborhood Hits	142	Target Neighborhood Hits	401	Shared Neighborhood Hits	40
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

ENL_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.051112 (rank : 82)
Query Neighborhood Hits	142	Target Neighborhood Hits	305	Shared Neighborhood Hits	30
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

GLU2B_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.051867 (rank : 79)
Query Neighborhood Hits	142	Target Neighborhood Hits	357	Shared Neighborhood Hits	26
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

ICAL_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.052766 (rank : 76)
Query Neighborhood Hits	142	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

IF2P_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.053699 (rank : 74)
Query Neighborhood Hits	142	Target Neighborhood Hits	889	Shared Neighborhood Hits	55
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

IWS1_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.055659 (rank : 67)
Query Neighborhood Hits	142	Target Neighborhood Hits	1241	Shared Neighborhood Hits	76
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.065908 (rank : 37)
Query Neighborhood Hits	142	Target Neighborhood Hits	1258	Shared Neighborhood Hits	61
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LAD1_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.059611 (rank : 56)
Query Neighborhood Hits	142	Target Neighborhood Hits	391	Shared Neighborhood Hits	31
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MAP1B_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.064191 (rank : 41)
Query Neighborhood Hits	142	Target Neighborhood Hits	903	Shared Neighborhood Hits	70
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MARCS_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.065187 (rank : 39)
Query Neighborhood Hits	142	Target Neighborhood Hits	204	Shared Neighborhood Hits	22
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MINT_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.050577 (rank : 86)
Query Neighborhood Hits	142	Target Neighborhood Hits	1514	Shared Neighborhood Hits	78
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MUC7_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.050722 (rank : 84)
Query Neighborhood Hits	142	Target Neighborhood Hits	538	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NASP_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.060409 (rank : 51)
Query Neighborhood Hits	142	Target Neighborhood Hits	709	Shared Neighborhood Hits	63
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NEUM_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.076280 (rank : 25)
Query Neighborhood Hits	142	Target Neighborhood Hits	132	Shared Neighborhood Hits	17
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

NEUM_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.087780 (rank : 16)
Query Neighborhood Hits	142	Target Neighborhood Hits	149	Shared Neighborhood Hits	22
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

NFH_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.064138 (rank : 42)
Query Neighborhood Hits	142	Target Neighborhood Hits	1242	Shared Neighborhood Hits	80
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NOLC1_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.098027 (rank : 13)
Query Neighborhood Hits	142	Target Neighborhood Hits	452	Shared Neighborhood Hits	48
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NSBP1_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.054100 (rank : 71)
Query Neighborhood Hits	142	Target Neighborhood Hits	251	Shared Neighborhood Hits	27
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

NUCKS_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.086482 (rank : 17)
Query Neighborhood Hits	142	Target Neighborhood Hits	143	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

PCLO_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.055422 (rank : 68)
Query Neighborhood Hits	142	Target Neighborhood Hits	2046	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PININ_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.054565 (rank : 70)
Query Neighborhood Hits	142	Target Neighborhood Hits	777	Shared Neighborhood Hits	59
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PRG4_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.054012 (rank : 72)
Query Neighborhood Hits	142	Target Neighborhood Hits	764	Shared Neighborhood Hits	48
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.061366 (rank : 48)
Query Neighborhood Hits	142	Target Neighborhood Hits	624	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

R51A1_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.053870 (rank : 73)
Query Neighborhood Hits	142	Target Neighborhood Hits	164	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

RL1D1_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.055151 (rank : 69)
Query Neighborhood Hits	142	Target Neighborhood Hits	180	Shared Neighborhood Hits	25
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

SFR12_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.052641 (rank : 77)
Query Neighborhood Hits	142	Target Neighborhood Hits	553	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SRRM1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.052368 (rank : 78)
Query Neighborhood Hits	142	Target Neighborhood Hits	690	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.061299 (rank : 49)
Query Neighborhood Hits	142	Target Neighborhood Hits	966	Shared Neighborhood Hits	55
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.059884 (rank : 54)
Query Neighborhood Hits	142	Target Neighborhood Hits	1296	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.059256 (rank : 59)
Query Neighborhood Hits	142	Target Neighborhood Hits	1470	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

T2FA_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.059358 (rank : 58)
Query Neighborhood Hits	142	Target Neighborhood Hits	228	Shared Neighborhood Hits	24
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TAF3_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.057059 (rank : 63)
Query Neighborhood Hits	142	Target Neighborhood Hits	463	Shared Neighborhood Hits	35
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TCOF_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.063294 (rank : 43)
Query Neighborhood Hits	142	Target Neighborhood Hits	543	Shared Neighborhood Hits	45
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.065709 (rank : 38)
Query Neighborhood Hits	142	Target Neighborhood Hits	471	Shared Neighborhood Hits	45
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TGON1_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.059615 (rank : 55)
Query Neighborhood Hits	142	Target Neighborhood Hits	243	Shared Neighborhood Hits	24
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

TGON2_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.061407 (rank : 47)
Query Neighborhood Hits	142	Target Neighborhood Hits	277	Shared Neighborhood Hits	20
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

TRDN_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.072218 (rank : 31)
Query Neighborhood Hits	142	Target Neighborhood Hits	542	Shared Neighborhood Hits	48
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TXLNB_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.051737 (rank : 80)
Query Neighborhood Hits	142	Target Neighborhood Hits	912	Shared Neighborhood Hits	49
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

TXND2_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.073653 (rank : 29)
Query Neighborhood Hits	142	Target Neighborhood Hits	793	Shared Neighborhood Hits	52
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

VCX1_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.077627 (rank : 24)
Query Neighborhood Hits	142	Target Neighborhood Hits	129	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

VCX3_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.081715 (rank : 20)
Query Neighborhood Hits	142	Target Neighborhood Hits	105	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

VCXC_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.083591 (rank : 19)
Query Neighborhood Hits	142	Target Neighborhood Hits	139	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

ZCPW1_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.053131 (rank : 75)
Query Neighborhood Hits	142	Target Neighborhood Hits	307	Shared Neighborhood Hits	27
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

Hits sorted by NC score

ADDB_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	142	Target Neighborhood Hits	142	Shared Neighborhood Hits	142
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).

ADDG_MOUSE
NC score	0.955089 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	142	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QYB5, Q9D2M5, Q9QYB6	Gene names	Add3, Addl
Domain Architecture
Description	Gamma-adducin (Adducin-like protein 70).

ADDG_HUMAN
NC score	0.951190 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	142	Target Neighborhood Hits	60	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UEY8, O43243, Q92773, Q9UEY7	Gene names	ADD3, ADDL
Domain Architecture
Description	Gamma-adducin (Adducin-like protein 70).

ADDA_HUMAN
NC score	0.937028 (rank : 4)	θ value	7.25522e-167 (rank : 5)
Query Neighborhood Hits	142	Target Neighborhood Hits	108	Shared Neighborhood Hits	14
SwissProt Accessions	P35611, Q13734, Q14729, Q16156, Q9UJB6	Gene names	ADD1, ADDA
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

ADDA_MOUSE
NC score	0.926090 (rank : 5)	θ value	3.04821e-165 (rank : 6)
Query Neighborhood Hits	142	Target Neighborhood Hits	198	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

ADDB_MOUSE
NC score	0.877296 (rank : 6)	θ value	0 (rank : 2)
Query Neighborhood Hits	142	Target Neighborhood Hits	574	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

SNUT3_MOUSE
NC score	0.166648 (rank : 7)	θ value	0.0148317 (rank : 20)
Query Neighborhood Hits	142	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K194, Q8BRA8, Q9CSV0	Gene names
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 3.

SNUT3_HUMAN
NC score	0.137294 (rank : 8)	θ value	0.125558 (rank : 28)
Query Neighborhood Hits	142	Target Neighborhood Hits	52	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WVK2, Q15410	Gene names
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 3 (U4/U6.U5 tri-snRNP-associated 27 kDa protein) (27K) (Nucleic acid-binding protein RY-1).

CF010_HUMAN
NC score	0.114855 (rank : 9)	θ value	0.00665767 (rank : 15)
Query Neighborhood Hits	142	Target Neighborhood Hits	329	Shared Neighborhood Hits	35
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

TGON2_HUMAN
NC score	0.113834 (rank : 10)	θ value	3.77169e-06 (rank : 7)
Query Neighborhood Hits	142	Target Neighborhood Hits	1037	Shared Neighborhood Hits	59
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

YTDC1_HUMAN
NC score	0.101903 (rank : 11)	θ value	0.00035302 (rank : 8)
Query Neighborhood Hits	142	Target Neighborhood Hits	458	Shared Neighborhood Hits	38
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

RBBP6_MOUSE
NC score	0.099325 (rank : 12)	θ value	0.21417 (rank : 31)
Query Neighborhood Hits	142	Target Neighborhood Hits	1014	Shared Neighborhood Hits	64
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

NOLC1_HUMAN
NC score	0.098027 (rank : 13)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	142	Target Neighborhood Hits	452	Shared Neighborhood Hits	48
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

TP53B_MOUSE
NC score	0.090252 (rank : 14)	θ value	0.00298849 (rank : 13)
Query Neighborhood Hits	142	Target Neighborhood Hits	644	Shared Neighborhood Hits	44
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TXND2_MOUSE
NC score	0.089756 (rank : 15)	θ value	0.000461057 (rank : 9)
Query Neighborhood Hits	142	Target Neighborhood Hits	828	Shared Neighborhood Hits	60
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

NEUM_MOUSE
NC score	0.087780 (rank : 16)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	142	Target Neighborhood Hits	149	Shared Neighborhood Hits	22
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

NUCKS_HUMAN
NC score	0.086482 (rank : 17)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	142	Target Neighborhood Hits	143	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

TP53B_HUMAN
NC score	0.084723 (rank : 18)	θ value	0.0736092 (rank : 26)
Query Neighborhood Hits	142	Target Neighborhood Hits	413	Shared Neighborhood Hits	43
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

VCXC_HUMAN
NC score	0.083591 (rank : 19)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	142	Target Neighborhood Hits	139	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H321	Gene names	VCXC
Domain Architecture	No domain graphic available
Description	VCX-C protein (Variably charged protein X-C).

VCX3_HUMAN
NC score	0.081715 (rank : 20)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	142	Target Neighborhood Hits	105	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

BASP_HUMAN
NC score	0.081580 (rank : 21)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	142	Target Neighborhood Hits	321	Shared Neighborhood Hits	34
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

LRRF1_HUMAN
NC score	0.079389 (rank : 22)	θ value	0.00869519 (rank : 17)
Query Neighborhood Hits	142	Target Neighborhood Hits	625	Shared Neighborhood Hits	42
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

MAP1B_MOUSE
NC score	0.077906 (rank : 23)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	142	Target Neighborhood Hits	977	Shared Neighborhood Hits	68
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

VCX1_HUMAN
NC score	0.077627 (rank : 24)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	142	Target Neighborhood Hits	129	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

NEUM_HUMAN
NC score	0.076280 (rank : 25)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	142	Target Neighborhood Hits	132	Shared Neighborhood Hits	17
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

DMP1_MOUSE
NC score	0.075712 (rank : 26)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	142	Target Neighborhood Hits	498	Shared Neighborhood Hits	48
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

GLU2B_HUMAN
NC score	0.074506 (rank : 27)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	142	Target Neighborhood Hits	377	Shared Neighborhood Hits	28
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

CYLC1_HUMAN
NC score	0.074307 (rank : 28)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	142	Target Neighborhood Hits	408	Shared Neighborhood Hits	33
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

TXND2_HUMAN
NC score	0.073653 (rank : 29)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	142	Target Neighborhood Hits	793	Shared Neighborhood Hits	52
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

RBBP6_HUMAN
NC score	0.073050 (rank : 30)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	142	Target Neighborhood Hits	1135	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TRDN_HUMAN
NC score	0.072218 (rank : 31)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	142	Target Neighborhood Hits	542	Shared Neighborhood Hits	48
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

MUC1_MOUSE
NC score	0.069544 (rank : 32)	θ value	0.0330416 (rank : 23)
Query Neighborhood Hits	142	Target Neighborhood Hits	388	Shared Neighborhood Hits	24
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

NFH_MOUSE
NC score	0.068623 (rank : 33)	θ value	0.000602161 (rank : 10)
Query Neighborhood Hits	142	Target Neighborhood Hits	2247	Shared Neighborhood Hits	96
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

BASP_MOUSE
NC score	0.067854 (rank : 34)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	142	Target Neighborhood Hits	260	Shared Neighborhood Hits	30
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SELPL_MOUSE
NC score	0.066339 (rank : 35)	θ value	0.0148317 (rank : 19)
Query Neighborhood Hits	142	Target Neighborhood Hits	588	Shared Neighborhood Hits	31
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

GP158_HUMAN
NC score	0.065932 (rank : 36)	θ value	0.00390308 (rank : 14)
Query Neighborhood Hits	142	Target Neighborhood Hits	221	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

IWS1_MOUSE
NC score	0.065908 (rank : 37)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	142	Target Neighborhood Hits	1258	Shared Neighborhood Hits	61
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TCOF_MOUSE
NC score	0.065709 (rank : 38)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	142	Target Neighborhood Hits	471	Shared Neighborhood Hits	45
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

MARCS_HUMAN
NC score	0.065187 (rank : 39)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	142	Target Neighborhood Hits	204	Shared Neighborhood Hits	22
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

DEK_MOUSE
NC score	0.064751 (rank : 40)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	142	Target Neighborhood Hits	280	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

MAP1B_HUMAN
NC score	0.064191 (rank : 41)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	142	Target Neighborhood Hits	903	Shared Neighborhood Hits	70
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

NFH_HUMAN
NC score	0.064138 (rank : 42)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	142	Target Neighborhood Hits	1242	Shared Neighborhood Hits	80
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TCOF_HUMAN
NC score	0.063294 (rank : 43)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	142	Target Neighborhood Hits	543	Shared Neighborhood Hits	45
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

MDC1_MOUSE
NC score	0.063123 (rank : 44)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	142	Target Neighborhood Hits	998	Shared Neighborhood Hits	48
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

AKA12_HUMAN
NC score	0.062758 (rank : 45)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	142	Target Neighborhood Hits	825	Shared Neighborhood Hits	60
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

DMP1_HUMAN
NC score	0.062266 (rank : 46)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	142	Target Neighborhood Hits	491	Shared Neighborhood Hits	36
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

TGON2_MOUSE
NC score	0.061407 (rank : 47)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	142	Target Neighborhood Hits	277	Shared Neighborhood Hits	20
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

PRG4_MOUSE
NC score	0.061366 (rank : 48)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	142	Target Neighborhood Hits	624	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SRRM1_MOUSE
NC score	0.061299 (rank : 49)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	142	Target Neighborhood Hits	966	Shared Neighborhood Hits	55
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

CJ047_MOUSE
NC score	0.060603 (rank : 50)	θ value	0.0736092 (rank : 25)
Query Neighborhood Hits	142	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

NASP_HUMAN
NC score	0.060409 (rank : 51)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	142	Target Neighborhood Hits	709	Shared Neighborhood Hits	63
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

LIMA1_MOUSE
NC score	0.060241 (rank : 52)	θ value	0.0252991 (rank : 21)
Query Neighborhood Hits	142	Target Neighborhood Hits	298	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

AFF1_HUMAN
NC score	0.060222 (rank : 53)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	142	Target Neighborhood Hits	506	Shared Neighborhood Hits	36
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

SRRM2_HUMAN
NC score	0.059884 (rank : 54)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	142	Target Neighborhood Hits	1296	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TGON1_MOUSE
NC score	0.059615 (rank : 55)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	142	Target Neighborhood Hits	243	Shared Neighborhood Hits	24
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

LAD1_MOUSE
NC score	0.059611 (rank : 56)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	142	Target Neighborhood Hits	391	Shared Neighborhood Hits	31
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

RP1L1_HUMAN
NC score	0.059474 (rank : 57)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	142	Target Neighborhood Hits	1072	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

T2FA_HUMAN
NC score	0.059358 (rank : 58)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	142	Target Neighborhood Hits	228	Shared Neighborhood Hits	24
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

SRRM2_MOUSE
NC score	0.059256 (rank : 59)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	142	Target Neighborhood Hits	1470	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PALM_MOUSE
NC score	0.058990 (rank : 60)	θ value	0.0431538 (rank : 24)
Query Neighborhood Hits	142	Target Neighborhood Hits	228	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

G3BP2_HUMAN
NC score	0.057895 (rank : 61)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	142	Target Neighborhood Hits	260	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UN86, O60606, O75149, Q9UPA1	Gene names	G3BP2, KIAA0660
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

NOC3L_HUMAN
NC score	0.057874 (rank : 62)	θ value	0.279714 (rank : 34)
Query Neighborhood Hits	142	Target Neighborhood Hits	135	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WTT2, Q9H5M6, Q9H9D8	Gene names	NOC3L, AD24, C10orf117, FAD24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

TAF3_MOUSE
NC score	0.057059 (rank : 63)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	142	Target Neighborhood Hits	463	Shared Neighborhood Hits	35
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

NACAM_MOUSE
NC score	0.056484 (rank : 64)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	142	Target Neighborhood Hits	1866	Shared Neighborhood Hits	55
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

EMSY_HUMAN
NC score	0.056207 (rank : 65)	θ value	0.125558 (rank : 27)
Query Neighborhood Hits	142	Target Neighborhood Hits	296	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

TRI44_HUMAN
NC score	0.055776 (rank : 66)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	142	Target Neighborhood Hits	393	Shared Neighborhood Hits	31
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

IWS1_HUMAN
NC score	0.055659 (rank : 67)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	142	Target Neighborhood Hits	1241	Shared Neighborhood Hits	76
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PCLO_HUMAN
NC score	0.055422 (rank : 68)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	142	Target Neighborhood Hits	2046	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RL1D1_HUMAN
NC score	0.055151 (rank : 69)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	142	Target Neighborhood Hits	180	Shared Neighborhood Hits	25
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

PININ_MOUSE
NC score	0.054565 (rank : 70)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	142	Target Neighborhood Hits	777	Shared Neighborhood Hits	59
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

NSBP1_HUMAN
NC score	0.054100 (rank : 71)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	142	Target Neighborhood Hits	251	Shared Neighborhood Hits	27
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

PRG4_HUMAN
NC score	0.054012 (rank : 72)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	142	Target Neighborhood Hits	764	Shared Neighborhood Hits	48
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

R51A1_MOUSE
NC score	0.053870 (rank : 73)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	142	Target Neighborhood Hits	164	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

IF2P_HUMAN
NC score	0.053699 (rank : 74)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	142	Target Neighborhood Hits	889	Shared Neighborhood Hits	55
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

ZCPW1_MOUSE
NC score	0.053131 (rank : 75)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	142	Target Neighborhood Hits	307	Shared Neighborhood Hits	27
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

ICAL_MOUSE
NC score	0.052766 (rank : 76)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	142	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

SFR12_HUMAN
NC score	0.052641 (rank : 77)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	142	Target Neighborhood Hits	553	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SRRM1_HUMAN
NC score	0.052368 (rank : 78)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	142	Target Neighborhood Hits	690	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

GLU2B_MOUSE
NC score	0.051867 (rank : 79)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	142	Target Neighborhood Hits	357	Shared Neighborhood Hits	26
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

TXLNB_HUMAN
NC score	0.051737 (rank : 80)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	142	Target Neighborhood Hits	912	Shared Neighborhood Hits	49
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

CN155_HUMAN
NC score	0.051418 (rank : 81)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	142	Target Neighborhood Hits	385	Shared Neighborhood Hits	30
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

ENL_HUMAN
NC score	0.051112 (rank : 82)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	142	Target Neighborhood Hits	305	Shared Neighborhood Hits	30
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

MYST3_HUMAN
NC score	0.050744 (rank : 83)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	142	Target Neighborhood Hits	772	Shared Neighborhood Hits	60
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MUC7_HUMAN
NC score	0.050722 (rank : 84)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	142	Target Neighborhood Hits	538	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

ABTAP_MOUSE
NC score	0.050599 (rank : 85)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	142	Target Neighborhood Hits	381	Shared Neighborhood Hits	37
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

MINT_MOUSE
NC score	0.050577 (rank : 86)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	142	Target Neighborhood Hits	1514	Shared Neighborhood Hits	78
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ACINU_HUMAN
NC score	0.050281 (rank : 87)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	142	Target Neighborhood Hits	828	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

DNMT1_HUMAN
NC score	0.050153 (rank : 88)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	142	Target Neighborhood Hits	401	Shared Neighborhood Hits	40
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

ACINU_MOUSE
NC score	0.050120 (rank : 89)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	142	Target Neighborhood Hits	712	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

RGS3_MOUSE
NC score	0.049461 (rank : 90)	θ value	0.00175202 (rank : 11)
Query Neighborhood Hits	142	Target Neighborhood Hits	1621	Shared Neighborhood Hits	47
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

MAP4_MOUSE
NC score	0.049113 (rank : 91)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	142	Target Neighborhood Hits	409	Shared Neighborhood Hits	29
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CEP35_HUMAN
NC score	0.048934 (rank : 92)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	142	Target Neighborhood Hits	811	Shared Neighborhood Hits	53
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

VEZA_HUMAN
NC score	0.048819 (rank : 93)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	142	Target Neighborhood Hits	107	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HBM0, Q9H2F4, Q9H2U5, Q9NT70, Q9NVW0, Q9UF91	Gene names	VEZT
Domain Architecture	No domain graphic available
Description	Vezatin.

MDC1_HUMAN
NC score	0.047278 (rank : 94)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	142	Target Neighborhood Hits	1446	Shared Neighborhood Hits	65
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

TRI44_MOUSE
NC score	0.046755 (rank : 95)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	142	Target Neighborhood Hits	327	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

MYST3_MOUSE
NC score	0.046485 (rank : 96)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	142	Target Neighborhood Hits	688	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

CTDP1_HUMAN
NC score	0.045483 (rank : 97)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	142	Target Neighborhood Hits	416	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

BCAS1_MOUSE
NC score	0.044615 (rank : 98)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	142	Target Neighborhood Hits	215	Shared Neighborhood Hits	18
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

G3BP2_MOUSE
NC score	0.043088 (rank : 99)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	142	Target Neighborhood Hits	258	Shared Neighborhood Hits	13
SwissProt Accessions	P97379, Q9R1B8	Gene names	G3bp2
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

NFM_HUMAN
NC score	0.041677 (rank : 100)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	142	Target Neighborhood Hits	1328	Shared Neighborhood Hits	71
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

KTN1_MOUSE
NC score	0.041591 (rank : 101)	θ value	0.00665767 (rank : 16)
Query Neighborhood Hits	142	Target Neighborhood Hits	1324	Shared Neighborhood Hits	50
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

NOC3L_MOUSE
NC score	0.041422 (rank : 102)	θ value	1.06291 (rank : 54)
Query Neighborhood Hits	142	Target Neighborhood Hits	177	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VI84, Q9JKM3	Gene names	Noc3l, Ad24, Fad24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

GP179_HUMAN
NC score	0.040574 (rank : 103)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	142	Target Neighborhood Hits	372	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

CCAR1_MOUSE
NC score	0.040382 (rank : 104)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	142	Target Neighborhood Hits	414	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

ZCPW1_HUMAN
NC score	0.040109 (rank : 105)	θ value	0.279714 (rank : 35)
Query Neighborhood Hits	142	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

INVO_MOUSE
NC score	0.039445 (rank : 106)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	142	Target Neighborhood Hits	474	Shared Neighborhood Hits	28
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

AN30A_HUMAN
NC score	0.037342 (rank : 107)	θ value	0.0330416 (rank : 22)
Query Neighborhood Hits	142	Target Neighborhood Hits	1119	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

LUZP1_MOUSE
NC score	0.037032 (rank : 108)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	142	Target Neighborhood Hits	940	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

OGFR_HUMAN
NC score	0.035893 (rank : 109)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	142	Target Neighborhood Hits	1582	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CCD19_HUMAN
NC score	0.035304 (rank : 110)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	142	Target Neighborhood Hits	639	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

ANK2_HUMAN
NC score	0.034695 (rank : 111)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	142	Target Neighborhood Hits	1615	Shared Neighborhood Hits	63
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

PPIG_HUMAN
NC score	0.034061 (rank : 112)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	142	Target Neighborhood Hits	670	Shared Neighborhood Hits	54
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

KMHN1_HUMAN
NC score	0.033599 (rank : 113)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	142	Target Neighborhood Hits	950	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

TARA_HUMAN
NC score	0.033182 (rank : 114)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	142	Target Neighborhood Hits	1626	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TRHY_HUMAN
NC score	0.032572 (rank : 115)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	142	Target Neighborhood Hits	1385	Shared Neighborhood Hits	48
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

WAPL_MOUSE
NC score	0.032400 (rank : 116)	θ value	1.38821 (rank : 64)
Query Neighborhood Hits	142	Target Neighborhood Hits	158	Shared Neighborhood Hits	20
SwissProt Accessions	Q65Z40, Q6ZQE9	Gene names	Wapal, Kiaa0261, Wapl
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2).

RBP24_HUMAN
NC score	0.031289 (rank : 117)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	142	Target Neighborhood Hits	1559	Shared Neighborhood Hits	52
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.031286 (rank : 118)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	142	Target Neighborhood Hits	1558	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

NALP5_MOUSE
NC score	0.030458 (rank : 119)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	142	Target Neighborhood Hits	560	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

MY18A_HUMAN
NC score	0.030190 (rank : 120)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	142	Target Neighborhood Hits	1929	Shared Neighborhood Hits	64
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CE290_HUMAN
NC score	0.030151 (rank : 121)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	142	Target Neighborhood Hits	1553	Shared Neighborhood Hits	52
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

MAP2_MOUSE
NC score	0.028792 (rank : 122)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	142	Target Neighborhood Hits	342	Shared Neighborhood Hits	37
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

TIP60_MOUSE
NC score	0.028591 (rank : 123)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	142	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

SIA7A_MOUSE
NC score	0.028161 (rank : 124)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	142	Target Neighborhood Hits	203	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QZ39, Q9JJP5	Gene names	St6galnac1, Siat7a
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

MYH11_MOUSE
NC score	0.028045 (rank : 125)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	142	Target Neighborhood Hits	1777	Shared Neighborhood Hits	69
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

TIP60_HUMAN
NC score	0.027975 (rank : 126)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	142	Target Neighborhood Hits	90	Shared Neighborhood Hits	12
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

CGRE1_MOUSE
NC score	0.027880 (rank : 127)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	142	Target Neighborhood Hits	173	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R1U2, Q9D1K1	Gene names	Cgref1, Cgr11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

ABCF1_HUMAN
NC score	0.027724 (rank : 128)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	142	Target Neighborhood Hits	343	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

TTBK1_HUMAN
NC score	0.027022 (rank : 129)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	142	Target Neighborhood Hits	1058	Shared Neighborhood Hits	37
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

MYH11_HUMAN
NC score	0.026966 (rank : 130)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	142	Target Neighborhood Hits	1806	Shared Neighborhood Hits	68
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NEB1_HUMAN
NC score	0.026803 (rank : 131)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	142	Target Neighborhood Hits	829	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

REST_HUMAN
NC score	0.026579 (rank : 132)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	142	Target Neighborhood Hits	1605	Shared Neighborhood Hits	62
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

MYH9_MOUSE
NC score	0.026401 (rank : 133)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	142	Target Neighborhood Hits	1829	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CD2L1_HUMAN
NC score	0.026351 (rank : 134)	θ value	0.00228821 (rank : 12)
Query Neighborhood Hits	142	Target Neighborhood Hits	1467	Shared Neighborhood Hits	59
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

TITIN_HUMAN
NC score	0.026072 (rank : 135)	θ value	0.47712 (rank : 42)
Query Neighborhood Hits	142	Target Neighborhood Hits	2923	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

SIA7A_HUMAN
NC score	0.025573 (rank : 136)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	142	Target Neighborhood Hits	177	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

MYH1_HUMAN
NC score	0.025527 (rank : 137)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	142	Target Neighborhood Hits	1478	Shared Neighborhood Hits	53
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

PEPL_HUMAN
NC score	0.025406 (rank : 138)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	142	Target Neighborhood Hits	1141	Shared Neighborhood Hits	42
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

MYH8_HUMAN
NC score	0.024764 (rank : 139)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	142	Target Neighborhood Hits	1610	Shared Neighborhood Hits	55
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

REST_MOUSE
NC score	0.024578 (rank : 140)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	142	Target Neighborhood Hits	1506	Shared Neighborhood Hits	50
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

CCD45_MOUSE
NC score	0.024571 (rank : 141)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	142	Target Neighborhood Hits	663	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

UBP1_HUMAN
NC score	0.024538 (rank : 142)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	142	Target Neighborhood Hits	259	Shared Neighborhood Hits	23
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

BRCA2_MOUSE
NC score	0.024414 (rank : 143)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	142	Target Neighborhood Hits	222	Shared Neighborhood Hits	18
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

MYH4_MOUSE
NC score	0.024355 (rank : 144)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	142	Target Neighborhood Hits	1476	Shared Neighborhood Hits	53
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

SRBS1_MOUSE
NC score	0.024114 (rank : 145)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	142	Target Neighborhood Hits	409	Shared Neighborhood Hits	13
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

MYRIP_HUMAN
NC score	0.023915 (rank : 146)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	142	Target Neighborhood Hits	269	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

SETBP_HUMAN
NC score	0.023677 (rank : 147)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	142	Target Neighborhood Hits	305	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

CPLX4_HUMAN
NC score	0.023454 (rank : 148)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	142	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z7G2	Gene names	CPLX4
Domain Architecture	No domain graphic available
Description	Complexin-4 (Complexin IV) (CPX IV).

BPAEA_MOUSE
NC score	0.023146 (rank : 149)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	142	Target Neighborhood Hits	1480	Shared Neighborhood Hits	50
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CPLX4_MOUSE
NC score	0.022474 (rank : 150)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	142	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q80WM3, Q8C8Y0, Q91WE5	Gene names	Cplx4
Domain Architecture	No domain graphic available
Description	Complexin-4 (Complexin IV) (CPX IV).

ERCC5_MOUSE
NC score	0.022384 (rank : 151)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	142	Target Neighborhood Hits	206	Shared Neighborhood Hits	21
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

ANLN_HUMAN
NC score	0.022267 (rank : 152)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	142	Target Neighborhood Hits	222	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

HELZ_HUMAN
NC score	0.022023 (rank : 153)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	142	Target Neighborhood Hits	198	Shared Neighborhood Hits	7
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

SYTL2_HUMAN
NC score	0.021852 (rank : 154)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	142	Target Neighborhood Hits	248	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SART3_MOUSE
NC score	0.020618 (rank : 155)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	142	Target Neighborhood Hits	341	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JLI8, Q6ZQI2, Q8BPK9, Q8C3B7, Q8CFU9	Gene names	Sart3, Kiaa0156
Domain Architecture	No domain graphic available
Description	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (mSART-3) (Tumor-rejection antigen SART3).

SLK_MOUSE
NC score	0.019336 (rank : 156)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	142	Target Neighborhood Hits	1798	Shared Neighborhood Hits	60
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TOP2B_MOUSE
NC score	0.018629 (rank : 157)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	142	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q64511, Q7TQG4	Gene names	Top2b
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

KI21A_MOUSE
NC score	0.018205 (rank : 158)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	142	Target Neighborhood Hits	1317	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

SLK_HUMAN
NC score	0.018012 (rank : 159)	θ value	0.47712 (rank : 41)
Query Neighborhood Hits	142	Target Neighborhood Hits	1775	Shared Neighborhood Hits	55
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

EVL_MOUSE
NC score	0.017323 (rank : 160)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	142	Target Neighborhood Hits	203	Shared Neighborhood Hits	12
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

PP4R1_MOUSE
NC score	0.017177 (rank : 161)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	142	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

CE110_MOUSE
NC score	0.016946 (rank : 162)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	142	Target Neighborhood Hits	170	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TSH4, Q6A072	Gene names	Cep110, Cp110, Kiaa0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

TBC10_MOUSE
NC score	0.016722 (rank : 163)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	142	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

SEPT9_HUMAN
NC score	0.015992 (rank : 164)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	142	Target Neighborhood Hits	706	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SART3_HUMAN
NC score	0.015253 (rank : 165)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	142	Target Neighborhood Hits	301	Shared Neighborhood Hits	11
SwissProt Accessions	Q15020, Q58F06, Q8IUS1, Q96J95	Gene names	SART3, KIAA0156, TIP110
Domain Architecture	No domain graphic available
Description	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (hSART-3) (Tat-interacting protein of 110 kDa) (Tip110).

ICB1_MOUSE
NC score	0.015038 (rank : 166)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	142	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

DDX46_HUMAN
NC score	0.014991 (rank : 167)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	142	Target Neighborhood Hits	357	Shared Neighborhood Hits	26
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

MYLK_HUMAN
NC score	0.014930 (rank : 168)	θ value	0.00869519 (rank : 18)
Query Neighborhood Hits	142	Target Neighborhood Hits	1328	Shared Neighborhood Hits	24
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

ZEP1_HUMAN
NC score	0.014456 (rank : 169)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	142	Target Neighborhood Hits	1036	Shared Neighborhood Hits	17
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

CAC1C_HUMAN
NC score	0.013852 (rank : 170)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	142	Target Neighborhood Hits	158	Shared Neighborhood Hits	10
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

TRPS1_MOUSE
NC score	0.012865 (rank : 171)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	142	Target Neighborhood Hits	609	Shared Neighborhood Hits	16
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

PB1_HUMAN
NC score	0.012739 (rank : 172)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	142	Target Neighborhood Hits	261	Shared Neighborhood Hits	7
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

LPIN2_HUMAN
NC score	0.012638 (rank : 173)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	142	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

NF2L2_MOUSE
NC score	0.011775 (rank : 174)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	142	Target Neighborhood Hits	183	Shared Neighborhood Hits	12
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

IL4RA_HUMAN
NC score	0.011720 (rank : 175)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	142	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

DDX46_MOUSE
NC score	0.010356 (rank : 176)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	142	Target Neighborhood Hits	358	Shared Neighborhood Hits	24
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DEN4C_HUMAN
NC score	0.009756 (rank : 177)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	142	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VZ89, Q6AI48, Q6ZUB3, Q8NCY7, Q9H6N4, Q9NUT1, Q9NWA5	Gene names	DENND4C, C9orf55
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 4C.

TCF8_HUMAN
NC score	0.009710 (rank : 178)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	142	Target Neighborhood Hits	1057	Shared Neighborhood Hits	31
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

LMAN1_HUMAN
NC score	0.008999 (rank : 179)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	142	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	P49257, Q12895, Q8N5I7, Q9UQG1, Q9UQG2, Q9UQG3, Q9UQG4, Q9UQG5, Q9UQG6, Q9UQG7, Q9UQG8, Q9UQG9, Q9UQH0, Q9UQH1, Q9UQH2	Gene names	LMAN1, ERGIC53, F5F8D
Domain Architecture
Description	ERGIC-53 protein precursor (ER-Golgi intermediate compartment 53 kDa protein) (Lectin, mannose-binding 1) (Gp58) (Intracellular mannose- specific lectin MR60).

LIRB3_HUMAN
NC score	0.008930 (rank : 180)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	142	Target Neighborhood Hits	125	Shared Neighborhood Hits	6
SwissProt Accessions	O75022, O15471, Q86U49	Gene names	LILRB3, ILT5, LIR3
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor (Leukocyte immunoglobulin-like receptor 3) (LIR-3) (Immunoglobulin- like transcript 5) (ILT-5) (Monocyte inhibitory receptor HL9) (CD85a antigen).

COPA_HUMAN
NC score	0.008904 (rank : 181)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	142	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	P53621	Gene names	COPA
Domain Architecture
Description	Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEPCOP) (HEP- COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin].

TBX2_HUMAN
NC score	0.007581 (rank : 182)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	142	Target Neighborhood Hits	195	Shared Neighborhood Hits	10
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

CAMKV_HUMAN
NC score	0.007159 (rank : 183)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	142	Target Neighborhood Hits	1084	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CSPG2_MOUSE
NC score	0.006504 (rank : 184)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	142	Target Neighborhood Hits	711	Shared Neighborhood Hits	20
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

SIPA1_MOUSE
NC score	0.006405 (rank : 185)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	142	Target Neighborhood Hits	158	Shared Neighborhood Hits	12
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

LATS1_HUMAN
NC score	0.005808 (rank : 186)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	142	Target Neighborhood Hits	1057	Shared Neighborhood Hits	26
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

WWP2_HUMAN
NC score	0.005623 (rank : 187)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	142	Target Neighborhood Hits	177	Shared Neighborhood Hits	13
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

HRH1_MOUSE
NC score	0.004224 (rank : 188)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	142	Target Neighborhood Hits	896	Shared Neighborhood Hits	4
SwissProt Accessions	P70174, Q91V75, Q91XN0, Q91XN1, Q91XN2, Q91XN3	Gene names	Hrh1, Bphs
Domain Architecture
Description	Histamine H1 receptor.

PLK3_MOUSE
NC score	0.003974 (rank : 189)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	142	Target Neighborhood Hits	863	Shared Neighborhood Hits	10
SwissProt Accessions	Q60806, Q60822, Q9R009	Gene names	Plk3, Cnk, Fnk
Domain Architecture
Description	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF- inducible kinase).

BCL6_HUMAN
NC score	0.003799 (rank : 190)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	142	Target Neighborhood Hits	922	Shared Neighborhood Hits	16
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

PCDLK_HUMAN
NC score	0.002112 (rank : 191)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	142	Target Neighborhood Hits	172	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYE9, Q9NXP8	Gene names	PCLKC
Domain Architecture	No domain graphic available
Description	Protocadherin LKC precursor (PC-LKC).

LGR6_HUMAN
NC score	0.001392 (rank : 192)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	142	Target Neighborhood Hits	344	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBX8, Q5T509, Q5T512, Q6UY15, Q86VU0, Q96K69, Q9BYD7	Gene names	LGR6
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 6 (VTS20631).

EVI1_MOUSE
NC score	0.001382 (rank : 193)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	142	Target Neighborhood Hits	826	Shared Neighborhood Hits	11
SwissProt Accessions	P14404	Gene names	Evi1, Evi-1
Domain Architecture	No domain graphic available
Description	Ecotropic virus integration 1 site protein.

ZBT40_HUMAN
NC score	0.000392 (rank : 194)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	142	Target Neighborhood Hits	949	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

ZN174_HUMAN
NC score	-0.000196 (rank : 195)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	142	Target Neighborhood Hits	744	Shared Neighborhood Hits	9
SwissProt Accessions	Q15697, Q9BQ34	Gene names	ZNF174, ZSCAN8
Domain Architecture
Description	Zinc finger protein 174 (AW-1) (Zinc finger and SCAN domain-containing protein 8).