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Network neighborhood for query Sequence : FRAT2_HUMAN

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FRAT2_HUMAN
SwissProt Accessions	O75474, Q5JTI0, Q8WUL9, Q9BYG2	Gene names	FRAT2
Domain Architecture
Description	GSK-3-binding protein FRAT2 (Frat-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FRAT2_HUMAN
θ value	2.38316e-93 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	26	Target Neighborhood Hits	26	Shared Neighborhood Hits	26
SwissProt Accessions	O75474, Q5JTI0, Q8WUL9, Q9BYG2	Gene names	FRAT2
Domain Architecture
Description	GSK-3-binding protein FRAT2 (Frat-2).

FRAT1_HUMAN
θ value	2.31901e-72 (rank : 2)	NC score	0.968568 (rank : 4)
Query Neighborhood Hits	26	Target Neighborhood Hits	48	Shared Neighborhood Hits	9
SwissProt Accessions	Q92837, Q8NE74, Q8TDW9	Gene names	FRAT1
Domain Architecture
Description	Proto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas) (Frat-1).

FRAT2_MOUSE
θ value	2.74572e-65 (rank : 3)	NC score	0.986188 (rank : 2)
Query Neighborhood Hits	26	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K025	Gene names	Frat2
Domain Architecture	No domain graphic available
Description	GSK-3-binding protein FRAT2 (Frat-2).

FRAT1_MOUSE
θ value	5.0155e-59 (rank : 4)	NC score	0.974620 (rank : 3)
Query Neighborhood Hits	26	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P70339	Gene names	Frat1
Domain Architecture
Description	Proto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas) (Frat-1).

ARHGA_MOUSE
θ value	0.365318 (rank : 5)	NC score	0.031983 (rank : 6)
Query Neighborhood Hits	26	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

DIAP1_HUMAN
θ value	0.813845 (rank : 6)	NC score	0.021227 (rank : 13)
Query Neighborhood Hits	26	Target Neighborhood Hits	784	Shared Neighborhood Hits	6
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

LBX1_HUMAN
θ value	0.813845 (rank : 7)	NC score	0.020906 (rank : 14)
Query Neighborhood Hits	26	Target Neighborhood Hits	357	Shared Neighborhood Hits	4
SwissProt Accessions	P52954	Gene names	LBX1
Domain Architecture
Description	Transcription factor LBX1.

OGFR_HUMAN
θ value	0.813845 (rank : 8)	NC score	0.022254 (rank : 12)
Query Neighborhood Hits	26	Target Neighborhood Hits	1582	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MLL2_HUMAN
θ value	1.06291 (rank : 9)	NC score	0.019415 (rank : 16)
Query Neighborhood Hits	26	Target Neighborhood Hits	1788	Shared Neighborhood Hits	10
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PLXB1_HUMAN
θ value	1.06291 (rank : 10)	NC score	0.022767 (rank : 11)
Query Neighborhood Hits	26	Target Neighborhood Hits	360	Shared Neighborhood Hits	10
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

COG2_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.037079 (rank : 5)
Query Neighborhood Hits	26	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q14746	Gene names	COG2, LDLC
Domain Architecture
Description	Conserved oligomeric Golgi complex component 2 (Low density lipoprotein receptor defect C-complementing protein).

YETS2_HUMAN
θ value	2.36792 (rank : 12)	NC score	0.026871 (rank : 9)
Query Neighborhood Hits	26	Target Neighborhood Hits	212	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

AFF1_MOUSE
θ value	3.0926 (rank : 13)	NC score	0.020046 (rank : 15)
Query Neighborhood Hits	26	Target Neighborhood Hits	351	Shared Neighborhood Hits	4
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

IF35_HUMAN
θ value	3.0926 (rank : 14)	NC score	0.028038 (rank : 8)
Query Neighborhood Hits	26	Target Neighborhood Hits	130	Shared Neighborhood Hits	5
SwissProt Accessions	O00303, Q8N978	Gene names	EIF3S5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

ZN692_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.004289 (rank : 26)
Query Neighborhood Hits	26	Target Neighborhood Hits	808	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BU19, Q5SRA5, Q5SRA6, Q9HBC9, Q9NW93, Q9NWY6, Q9UF97	Gene names	ZNF692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.

AMOT_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.013136 (rank : 20)
Query Neighborhood Hits	26	Target Neighborhood Hits	712	Shared Neighborhood Hits	7
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

BCL9_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.017186 (rank : 18)
Query Neighborhood Hits	26	Target Neighborhood Hits	1008	Shared Neighborhood Hits	9
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

DGKI_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.009244 (rank : 23)
Query Neighborhood Hits	26	Target Neighborhood Hits	609	Shared Neighborhood Hits	3
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

KCNN3_MOUSE
θ value	5.27518 (rank : 19)	NC score	0.011207 (rank : 21)
Query Neighborhood Hits	26	Target Neighborhood Hits	171	Shared Neighborhood Hits	2
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

TM108_HUMAN
θ value	5.27518 (rank : 20)	NC score	0.031427 (rank : 7)
Query Neighborhood Hits	26	Target Neighborhood Hits	166	Shared Neighborhood Hits	6
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ABCA2_HUMAN
θ value	6.88961 (rank : 21)	NC score	0.006552 (rank : 25)
Query Neighborhood Hits	26	Target Neighborhood Hits	143	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

HCN2_HUMAN
θ value	6.88961 (rank : 22)	NC score	0.009389 (rank : 22)
Query Neighborhood Hits	26	Target Neighborhood Hits	369	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HXD12_MOUSE
θ value	6.88961 (rank : 23)	NC score	0.006896 (rank : 24)
Query Neighborhood Hits	26	Target Neighborhood Hits	370	Shared Neighborhood Hits	4
SwissProt Accessions	P23812	Gene names	Hoxd12, Hox-4.7, Hoxd-12
Domain Architecture
Description	Homeobox protein Hox-D12 (Hox-4.7) (Hox-5.6).

K0460_MOUSE
θ value	6.88961 (rank : 24)	NC score	0.015103 (rank : 19)
Query Neighborhood Hits	26	Target Neighborhood Hits	374	Shared Neighborhood Hits	5
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

NELFB_HUMAN
θ value	6.88961 (rank : 25)	NC score	0.018081 (rank : 17)
Query Neighborhood Hits	26	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WX92, Q96EW5, Q9H9R4, Q9ULN8, Q9Y3W0	Gene names	NELFB, COBRA1, KIAA1182
Domain Architecture
Description	Negative elongation factor B (NELF-B) (Cofactor of BRCA1).

IL4RA_HUMAN
θ value	8.99809 (rank : 26)	NC score	0.023631 (rank : 10)
Query Neighborhood Hits	26	Target Neighborhood Hits	144	Shared Neighborhood Hits	6
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

Hits sorted by NC score

FRAT2_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.38316e-93 (rank : 1)
Query Neighborhood Hits	26	Target Neighborhood Hits	26	Shared Neighborhood Hits	26
SwissProt Accessions	O75474, Q5JTI0, Q8WUL9, Q9BYG2	Gene names	FRAT2
Domain Architecture
Description	GSK-3-binding protein FRAT2 (Frat-2).

FRAT2_MOUSE
NC score	0.986188 (rank : 2)	θ value	2.74572e-65 (rank : 3)
Query Neighborhood Hits	26	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K025	Gene names	Frat2
Domain Architecture	No domain graphic available
Description	GSK-3-binding protein FRAT2 (Frat-2).

FRAT1_MOUSE
NC score	0.974620 (rank : 3)	θ value	5.0155e-59 (rank : 4)
Query Neighborhood Hits	26	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P70339	Gene names	Frat1
Domain Architecture
Description	Proto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas) (Frat-1).

FRAT1_HUMAN
NC score	0.968568 (rank : 4)	θ value	2.31901e-72 (rank : 2)
Query Neighborhood Hits	26	Target Neighborhood Hits	48	Shared Neighborhood Hits	9
SwissProt Accessions	Q92837, Q8NE74, Q8TDW9	Gene names	FRAT1
Domain Architecture
Description	Proto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas) (Frat-1).

COG2_HUMAN
NC score	0.037079 (rank : 5)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	26	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q14746	Gene names	COG2, LDLC
Domain Architecture
Description	Conserved oligomeric Golgi complex component 2 (Low density lipoprotein receptor defect C-complementing protein).

ARHGA_MOUSE
NC score	0.031983 (rank : 6)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	26	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C033, Q5DU38, Q80VH8, Q8BW76, Q922S7	Gene names	Arhgef10, Kiaa0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

TM108_HUMAN
NC score	0.031427 (rank : 7)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	26	Target Neighborhood Hits	166	Shared Neighborhood Hits	6
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

IF35_HUMAN
NC score	0.028038 (rank : 8)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	26	Target Neighborhood Hits	130	Shared Neighborhood Hits	5
SwissProt Accessions	O00303, Q8N978	Gene names	EIF3S5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

YETS2_HUMAN
NC score	0.026871 (rank : 9)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	26	Target Neighborhood Hits	212	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

IL4RA_HUMAN
NC score	0.023631 (rank : 10)	θ value	8.99809 (rank : 26)
Query Neighborhood Hits	26	Target Neighborhood Hits	144	Shared Neighborhood Hits	6
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

PLXB1_HUMAN
NC score	0.022767 (rank : 11)	θ value	1.06291 (rank : 10)
Query Neighborhood Hits	26	Target Neighborhood Hits	360	Shared Neighborhood Hits	10
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

OGFR_HUMAN
NC score	0.022254 (rank : 12)	θ value	0.813845 (rank : 8)
Query Neighborhood Hits	26	Target Neighborhood Hits	1582	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

DIAP1_HUMAN
NC score	0.021227 (rank : 13)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	26	Target Neighborhood Hits	784	Shared Neighborhood Hits	6
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

LBX1_HUMAN
NC score	0.020906 (rank : 14)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	26	Target Neighborhood Hits	357	Shared Neighborhood Hits	4
SwissProt Accessions	P52954	Gene names	LBX1
Domain Architecture
Description	Transcription factor LBX1.

AFF1_MOUSE
NC score	0.020046 (rank : 15)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	26	Target Neighborhood Hits	351	Shared Neighborhood Hits	4
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

MLL2_HUMAN
NC score	0.019415 (rank : 16)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	26	Target Neighborhood Hits	1788	Shared Neighborhood Hits	10
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NELFB_HUMAN
NC score	0.018081 (rank : 17)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	26	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WX92, Q96EW5, Q9H9R4, Q9ULN8, Q9Y3W0	Gene names	NELFB, COBRA1, KIAA1182
Domain Architecture
Description	Negative elongation factor B (NELF-B) (Cofactor of BRCA1).

BCL9_HUMAN
NC score	0.017186 (rank : 18)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	26	Target Neighborhood Hits	1008	Shared Neighborhood Hits	9
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

K0460_MOUSE
NC score	0.015103 (rank : 19)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	26	Target Neighborhood Hits	374	Shared Neighborhood Hits	5
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

AMOT_HUMAN
NC score	0.013136 (rank : 20)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	26	Target Neighborhood Hits	712	Shared Neighborhood Hits	7
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

KCNN3_MOUSE
NC score	0.011207 (rank : 21)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	26	Target Neighborhood Hits	171	Shared Neighborhood Hits	2
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

HCN2_HUMAN
NC score	0.009389 (rank : 22)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	26	Target Neighborhood Hits	369	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

DGKI_HUMAN
NC score	0.009244 (rank : 23)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	26	Target Neighborhood Hits	609	Shared Neighborhood Hits	3
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

HXD12_MOUSE
NC score	0.006896 (rank : 24)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	26	Target Neighborhood Hits	370	Shared Neighborhood Hits	4
SwissProt Accessions	P23812	Gene names	Hoxd12, Hox-4.7, Hoxd-12
Domain Architecture
Description	Homeobox protein Hox-D12 (Hox-4.7) (Hox-5.6).

ABCA2_HUMAN
NC score	0.006552 (rank : 25)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	26	Target Neighborhood Hits	143	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ZN692_HUMAN
NC score	0.004289 (rank : 26)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	26	Target Neighborhood Hits	808	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BU19, Q5SRA5, Q5SRA6, Q9HBC9, Q9NW93, Q9NWY6, Q9UF97	Gene names	ZNF692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.