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Network neighborhood for query Sequence : IP6K1_HUMAN

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IP6K1_HUMAN
SwissProt Accessions	Q92551, Q7L3I7, Q96E38	Gene names	IHPK1, IP6K1, KIAA0263
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 1 (EC 2.7.4.21) (InsP6 kinase 1) (Inositol hexakisphosphate kinase 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IP6K1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q92551, Q7L3I7, Q96E38	Gene names	IHPK1, IP6K1, KIAA0263
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 1 (EC 2.7.4.21) (InsP6 kinase 1) (Inositol hexakisphosphate kinase 1).

IP6K1_MOUSE
θ value	0 (rank : 2)	NC score	0.999331 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PD10, Q9QXV6	Gene names	Ihpk1, Ip6k1
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 1 (EC 2.7.4.21) (InsP6 kinase 1) (Inositol hexakisphosphate kinase 1).

IP6K3_HUMAN
θ value	4.77967e-110 (rank : 3)	NC score	0.979518 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PC2, Q96MQ9	Gene names	IHPK3, IP6K3
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 3 (EC 2.7.4.21) (InsP6 kinase 3) (Inositol hexakisphosphate kinase 3).

IP6K2_HUMAN
θ value	3.54468e-105 (rank : 4)	NC score	0.974549 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHH9, Q6P0N8, Q9BSZ6, Q9BUW3, Q9H4P7, Q9NT63, Q9UFU6	Gene names	IHPK2, IP6K2
Domain Architecture	No domain graphic available
Description	Inositol hexakisphosphate kinase 2 (EC 2.7.4.21) (InsP6 kinase 2) (Inositol hexakisphosphate kinase 2) (P(i)-uptake stimulator) (PiUS).

IP6K2_MOUSE
θ value	1.3939e-101 (rank : 5)	NC score	0.970012 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q80V72	Gene names	Ihpk2, Ip6k2
Domain Architecture	No domain graphic available
Description	Inositol hexakisphosphate kinase 2 (EC 2.7.4.21) (InsP6 kinase 2) (Inositol hexakisphosphate kinase 2) (P(i)-uptake stimulator) (PiUS).

IP6K3_MOUSE
θ value	2.08291e-97 (rank : 6)	NC score	0.976973 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BWD2	Gene names	Ihpk3, Ip6k3
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 3 (EC 2.7.4.21) (InsP6 kinase 3) (Inositol hexakisphosphate kinase 3).

IPMK_MOUSE
θ value	2.06002e-20 (rank : 7)	NC score	0.719128 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TT16, Q8BZ11, Q8BZA8, Q9CWM9	Gene names	Ipmk, Impk
Domain Architecture	No domain graphic available
Description	Inositol polyphosphate multikinase (EC 2.7.1.151) (Inositol 1,3,4,6- tetrakisphosphate 5-kinase).

IPMK_HUMAN
θ value	2.27762e-19 (rank : 8)	NC score	0.707015 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	35	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NFU5	Gene names	IPMK, IMPK
Domain Architecture	No domain graphic available
Description	Inositol polyphosphate multikinase (EC 2.7.1.151) (Inositol 1,3,4,6- tetrakisphosphate 5-kinase).

HIPK3_MOUSE
θ value	1.81305 (rank : 9)	NC score	0.007033 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	857	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

HIPK3_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.005504 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	867	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H422, O14632, Q2PBG4, Q2PBG5, Q92632, Q9HAS2	Gene names	HIPK3, DYRK6, FIST3, PKY
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Homolog of protein kinase YAK1) (Fas-interacting serine/threonine-protein kinase) (FIST) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

MAP2_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.012252 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	348	Shared Neighborhood Hits	3
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

LATS2_MOUSE
θ value	5.27518 (rank : 12)	NC score	0.001173 (rank : 21)
Query Neighborhood Hits	20	Target Neighborhood Hits	879	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TSJ6, Q8CDJ4, Q9JMI3	Gene names	Lats2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein).

LRC55_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.004528 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	257	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZSA7	Gene names	LRRC55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

CABYR_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.010988 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

CYLD_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.009439 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q80TQ2, Q80VB3, Q8BXZ3, Q8BYL9, Q8CGB0	Gene names	Cyld, Cyld1, Kiaa0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

IP3KA_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.064608 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	60	Shared Neighborhood Hits	10
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

IP3KA_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.065965 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R071	Gene names	Itpka
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

KC1D_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.004684 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	737	Shared Neighborhood Hits	7
SwissProt Accessions	P48730, Q96KZ6, Q9BTN5	Gene names	CSNK1D
Domain Architecture
Description	Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta) (CKId).

KC1D_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.004684 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	737	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DC28, Q3TZK2, Q99KK4	Gene names	Csnk1d
Domain Architecture
Description	Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta) (CKId).

UB7I1_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.011681 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

IP3KB_HUMAN
θ value	θ > 10 (rank : 21)	NC score	0.096990 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	124	Shared Neighborhood Hits	8
SwissProt Accessions	P27987, Q5VWL9, Q5VWM0, Q96BZ2, Q96JS1, Q9UH47	Gene names	ITPKB
Domain Architecture
Description	Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase B) (IP3K B) (IP3 3-kinase B) (IP3K-B).

Hits sorted by NC score

IP6K1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q92551, Q7L3I7, Q96E38	Gene names	IHPK1, IP6K1, KIAA0263
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 1 (EC 2.7.4.21) (InsP6 kinase 1) (Inositol hexakisphosphate kinase 1).

IP6K1_MOUSE
NC score	0.999331 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PD10, Q9QXV6	Gene names	Ihpk1, Ip6k1
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 1 (EC 2.7.4.21) (InsP6 kinase 1) (Inositol hexakisphosphate kinase 1).

IP6K3_HUMAN
NC score	0.979518 (rank : 3)	θ value	4.77967e-110 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PC2, Q96MQ9	Gene names	IHPK3, IP6K3
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 3 (EC 2.7.4.21) (InsP6 kinase 3) (Inositol hexakisphosphate kinase 3).

IP6K3_MOUSE
NC score	0.976973 (rank : 4)	θ value	2.08291e-97 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BWD2	Gene names	Ihpk3, Ip6k3
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 3 (EC 2.7.4.21) (InsP6 kinase 3) (Inositol hexakisphosphate kinase 3).

IP6K2_HUMAN
NC score	0.974549 (rank : 5)	θ value	3.54468e-105 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHH9, Q6P0N8, Q9BSZ6, Q9BUW3, Q9H4P7, Q9NT63, Q9UFU6	Gene names	IHPK2, IP6K2
Domain Architecture	No domain graphic available
Description	Inositol hexakisphosphate kinase 2 (EC 2.7.4.21) (InsP6 kinase 2) (Inositol hexakisphosphate kinase 2) (P(i)-uptake stimulator) (PiUS).

IP6K2_MOUSE
NC score	0.970012 (rank : 6)	θ value	1.3939e-101 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q80V72	Gene names	Ihpk2, Ip6k2
Domain Architecture	No domain graphic available
Description	Inositol hexakisphosphate kinase 2 (EC 2.7.4.21) (InsP6 kinase 2) (Inositol hexakisphosphate kinase 2) (P(i)-uptake stimulator) (PiUS).

IPMK_MOUSE
NC score	0.719128 (rank : 7)	θ value	2.06002e-20 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TT16, Q8BZ11, Q8BZA8, Q9CWM9	Gene names	Ipmk, Impk
Domain Architecture	No domain graphic available
Description	Inositol polyphosphate multikinase (EC 2.7.1.151) (Inositol 1,3,4,6- tetrakisphosphate 5-kinase).

IPMK_HUMAN
NC score	0.707015 (rank : 8)	θ value	2.27762e-19 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	35	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NFU5	Gene names	IPMK, IMPK
Domain Architecture	No domain graphic available
Description	Inositol polyphosphate multikinase (EC 2.7.1.151) (Inositol 1,3,4,6- tetrakisphosphate 5-kinase).

IP3KB_HUMAN
NC score	0.096990 (rank : 9)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	20	Target Neighborhood Hits	124	Shared Neighborhood Hits	8
SwissProt Accessions	P27987, Q5VWL9, Q5VWM0, Q96BZ2, Q96JS1, Q9UH47	Gene names	ITPKB
Domain Architecture
Description	Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase B) (IP3K B) (IP3 3-kinase B) (IP3K-B).

IP3KA_MOUSE
NC score	0.065965 (rank : 10)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R071	Gene names	Itpka
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

IP3KA_HUMAN
NC score	0.064608 (rank : 11)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	60	Shared Neighborhood Hits	10
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

MAP2_HUMAN
NC score	0.012252 (rank : 12)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	348	Shared Neighborhood Hits	3
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

UB7I1_MOUSE
NC score	0.011681 (rank : 13)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

CABYR_HUMAN
NC score	0.010988 (rank : 14)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

CYLD_MOUSE
NC score	0.009439 (rank : 15)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q80TQ2, Q80VB3, Q8BXZ3, Q8BYL9, Q8CGB0	Gene names	Cyld, Cyld1, Kiaa0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

HIPK3_MOUSE
NC score	0.007033 (rank : 16)	θ value	1.81305 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	857	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

HIPK3_HUMAN
NC score	0.005504 (rank : 17)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	867	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H422, O14632, Q2PBG4, Q2PBG5, Q92632, Q9HAS2	Gene names	HIPK3, DYRK6, FIST3, PKY
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Homolog of protein kinase YAK1) (Fas-interacting serine/threonine-protein kinase) (FIST) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

KC1D_HUMAN
NC score	0.004684 (rank : 18)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	737	Shared Neighborhood Hits	7
SwissProt Accessions	P48730, Q96KZ6, Q9BTN5	Gene names	CSNK1D
Domain Architecture
Description	Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta) (CKId).

KC1D_MOUSE
NC score	0.004684 (rank : 19)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	737	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DC28, Q3TZK2, Q99KK4	Gene names	Csnk1d
Domain Architecture
Description	Casein kinase I isoform delta (EC 2.7.11.1) (CKI-delta) (CKId).

LRC55_HUMAN
NC score	0.004528 (rank : 20)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	257	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZSA7	Gene names	LRRC55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

LATS2_MOUSE
NC score	0.001173 (rank : 21)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	879	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TSJ6, Q8CDJ4, Q9JMI3	Gene names	Lats2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein).