Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : ERAL_HUMAN

For an explanation of this page, click here

ERAL_HUMAN
SwissProt Accessions	O75616, O75617, Q8WUY4, Q96LE2, Q96TC0	Gene names	ERAL1, HERA
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (hERA) (ERA-W) (Conserved ERA-like GTPase) (CEGA).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ERAL_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	O75616, O75617, Q8WUY4, Q96LE2, Q96TC0	Gene names	ERAL1, HERA
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (hERA) (ERA-W) (Conserved ERA-like GTPase) (CEGA).

ERAL_MOUSE
θ value	0 (rank : 2)	NC score	0.988151 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	48
SwissProt Accessions	Q9CZU4, Q6NV78, Q925U1	Gene names	Eral1
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (ERA-W) (Conserved ERA-like GTPase) (CEGA).

GIMA4_HUMAN
θ value	1.29631e-06 (rank : 3)	NC score	0.295927 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	217	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NUV9	Gene names	GIMAP4, IAN1, IMAP4
Domain Architecture
Description	GTPase, IMAP family member 4 (Immunity-associated protein 4) (Immunity-associated nucleotide 1 protein) (hIAN1).

GNL1_HUMAN
θ value	0.00035302 (rank : 4)	NC score	0.261418 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	P36915	Gene names	GNL1, HSR1
Domain Architecture
Description	Guanine nucleotide-binding protein-like 1 (GTP-binding protein HSR1).

GIMA4_MOUSE
θ value	0.00102713 (rank : 5)	NC score	0.282234 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q99JY3	Gene names	Gimap4, Ian1, Imap4
Domain Architecture
Description	GTPase, IMAP family member 4 (Immunity-associated protein 4) (Immunity-associated nucleotide 1 protein).

GTPB5_HUMAN
θ value	0.00134147 (rank : 6)	NC score	0.268743 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4K7, Q96I17, Q9NVG9, Q9UFR4	Gene names	GTPBP5
Domain Architecture
Description	Putative GTP-binding protein 5.

GNL1_MOUSE
θ value	0.00175202 (rank : 7)	NC score	0.245514 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	P36916	Gene names	Gnl1, Gna-rs1, Mmr1
Domain Architecture
Description	Guanine nucleotide-binding protein-like 1 (GTP-binding protein MMR1).

GIMA1_HUMAN
θ value	0.0148317 (rank : 8)	NC score	0.230258 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WWP7, Q8NAZ0	Gene names	GIMAP1, IMAP1
Domain Architecture
Description	GTPase, IMAP family member 1 (Immunity-associated protein 1) (hIMAP1).

GIMA7_HUMAN
θ value	0.0252991 (rank : 9)	NC score	0.237272 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	93	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NHV1	Gene names	GIMAP7, IAN7
Domain Architecture	No domain graphic available
Description	GTPase, IMAP family member 7 (Immunity-associated nucleotide 7 protein).

DRG1_HUMAN
θ value	0.0330416 (rank : 10)	NC score	0.217024 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y295, Q6FGP8, Q8WW69, Q9UGF2	Gene names	DRG1
Domain Architecture
Description	Developmentally-regulated GTP-binding protein 1 (DRG 1).

DRG1_MOUSE
θ value	0.0330416 (rank : 11)	NC score	0.216984 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	P32233	Gene names	Drg1, Drg, Nedd-3, Nedd3
Domain Architecture
Description	Developmentally-regulated GTP-binding protein 1 (DRG 1) (Protein NEDD3) (Neural precursor cell expressed developmentally down-regulated protein 3).

DRG2_MOUSE
θ value	0.0330416 (rank : 12)	NC score	0.204824 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QXB9	Gene names	Drg2
Domain Architecture
Description	Developmentally-regulated GTP-binding protein 2 (DRG 2).

NOG1_HUMAN
θ value	0.0431538 (rank : 13)	NC score	0.177312 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZE4, O95446, Q9NVJ8	Gene names	GTPBP4, CRFG, NOG1
Domain Architecture
Description	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB).

REM1_HUMAN
θ value	0.0431538 (rank : 14)	NC score	0.104807 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	247	Shared Neighborhood Hits	22
SwissProt Accessions	O75628, Q9NP57	Gene names	REM1, GES, REM
Domain Architecture
Description	GTP-binding protein REM 1 (Rad and Gem-like GTP-binding protein 1) (GTPase-regulating endothelial cell sprouting).

DRG2_HUMAN
θ value	0.0563607 (rank : 15)	NC score	0.203694 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	P55039, Q9BWB2	Gene names	DRG2
Domain Architecture
Description	Developmentally-regulated GTP-binding protein 2 (DRG 2).

NOG1_MOUSE
θ value	0.0736092 (rank : 16)	NC score	0.176299 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	93	Shared Neighborhood Hits	13
SwissProt Accessions	Q99ME9, Q99K16, Q99P78, Q9CT02	Gene names	Gtpbp4, Crfg, Nog1
Domain Architecture
Description	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB).

TP53B_HUMAN
θ value	0.0736092 (rank : 17)	NC score	0.099117 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	413	Shared Neighborhood Hits	4
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

GIMA5_HUMAN
θ value	0.0961366 (rank : 18)	NC score	0.225638 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q96F15, Q6IA75, Q96NE4, Q9NUK9	Gene names	GIMAP5, IAN4L1, IMAP3
Domain Architecture
Description	GTPase, IMAP family member 5 (Immunity-associated nucleotide 4-like 1 protein) (Immunity-associated protein 3) (IAN-5).

GEM_MOUSE
θ value	0.125558 (rank : 19)	NC score	0.105403 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	233	Shared Neighborhood Hits	22
SwissProt Accessions	P55041, Q8JZS1	Gene names	Gem, Kir
Domain Architecture
Description	GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR).

GIMA1_MOUSE
θ value	0.163984 (rank : 20)	NC score	0.216567 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	P70224	Gene names	Gimap1, Imap1, Imap38
Domain Architecture	No domain graphic available
Description	GTPase, IMAP family member 1 (Immunity-associated protein 1) (Immune- associated protein 38) (IAP38).

GIMA3_MOUSE
θ value	0.21417 (rank : 21)	NC score	0.203874 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	Q99MI6, Q4VBX0, Q549W4, Q8CF04	Gene names	Gimap3, Ian4
Domain Architecture
Description	GTPase, IMAP family member 3 (Immunity-associated nucleotide 4 protein).

GNL3_HUMAN
θ value	0.21417 (rank : 22)	NC score	0.137479 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	83	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BVP2, Q96SV6, Q96SV7, Q9UJY0	Gene names	GNL3, E2IG3, NS
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein-like 3 (Nucleolar GTP-binding protein 3) (Nucleostemin) (E2-induced gene 3-protein) (Novel nucleolar protein 47) (NNP47).

GEM_HUMAN
θ value	0.279714 (rank : 23)	NC score	0.102256 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	238	Shared Neighborhood Hits	22
SwissProt Accessions	P55040	Gene names	GEM, KIR
Domain Architecture
Description	GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR).

RBM16_HUMAN
θ value	0.279714 (rank : 24)	NC score	0.057424 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	300	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

RIT1_HUMAN
θ value	0.279714 (rank : 25)	NC score	0.062876 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	265	Shared Neighborhood Hits	24
SwissProt Accessions	Q92963, O00646, O00720	Gene names	RIT1, RIBB, RIT, ROC1
Domain Architecture
Description	GTP-binding protein Rit1 (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1).

RAD_HUMAN
θ value	0.365318 (rank : 26)	NC score	0.094415 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	224	Shared Neighborhood Hits	21
SwissProt Accessions	P55042, Q96F39	Gene names	RRAD, RAD
Domain Architecture
Description	GTP-binding protein RAD (RAS associated with diabetes) (RAD1).

RALB_HUMAN
θ value	0.365318 (rank : 27)	NC score	0.057784 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	274	Shared Neighborhood Hits	23
SwissProt Accessions	P11234	Gene names	RALB
Domain Architecture
Description	Ras-related protein Ral-B.

REM1_MOUSE
θ value	0.365318 (rank : 28)	NC score	0.097216 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	255	Shared Neighborhood Hits	22
SwissProt Accessions	O35929	Gene names	Rem1, Rem
Domain Architecture
Description	GTP-binding protein REM 1 (Rad and Gem-like GTP-binding protein 1).

MIRO2_HUMAN
θ value	0.47712 (rank : 29)	NC score	0.080353 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	226	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IXI1, Q8NF53, Q96C13, Q96S17, Q9BT60, Q9H7M8	Gene names	RHOT2, ARHT2
Domain Architecture	No domain graphic available
Description	Mitochondrial Rho GTPase 2 (EC 3.6.5.-) (MIRO-2) (hMiro-2) (Ras homolog gene family member T2).

RAD_MOUSE
θ value	0.47712 (rank : 30)	NC score	0.103207 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	216	Shared Neighborhood Hits	22
SwissProt Accessions	O88667	Gene names	Rrad
Domain Architecture
Description	GTP-binding protein RAD.

REM2_HUMAN
θ value	0.47712 (rank : 31)	NC score	0.091201 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	237	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IYK8, Q8N8R8	Gene names	REM2
Domain Architecture	No domain graphic available
Description	GTP-binding protein REM 2 (Rad and Gem-like GTP-binding protein 2).

REM2_MOUSE
θ value	0.47712 (rank : 32)	NC score	0.091884 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	238	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VEL9, Q8BPB1	Gene names	Rem2
Domain Architecture	No domain graphic available
Description	GTP-binding protein REM 2 (Rad and Gem-like GTP-binding protein 2).

NOG2_HUMAN
θ value	0.62314 (rank : 33)	NC score	0.132537 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q13823, Q9BWN7	Gene names	GNL2, NGP1
Domain Architecture
Description	Nucleolar GTP-binding protein 2 (Autoantigen NGP-1).

NOG2_MOUSE
θ value	0.62314 (rank : 34)	NC score	0.133719 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LH1, Q8BIF8	Gene names	Gnl2
Domain Architecture	No domain graphic available
Description	Nucleolar GTP-binding protein 2.

RALB_MOUSE
θ value	0.62314 (rank : 35)	NC score	0.056214 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	274	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JIW9, Q3TVS5	Gene names	Ralb
Domain Architecture
Description	Ras-related protein Ral-B.

RIT1_MOUSE
θ value	0.62314 (rank : 36)	NC score	0.060051 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	266	Shared Neighborhood Hits	23
SwissProt Accessions	P70426	Gene names	Rit1, Rit
Domain Architecture
Description	GTP-binding protein Rit1 (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1).

GIMA5_MOUSE
θ value	0.813845 (rank : 37)	NC score	0.191107 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	35	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BWF2, Q501L7, Q549X3	Gene names	Gimap5, Ian4l1, Imap3
Domain Architecture
Description	GTPase, IMAP family member 5 (Immunity-associated nucleotide 4-like 1 protein) (Immunity-associated protein 3).

TP53B_MOUSE
θ value	0.813845 (rank : 38)	NC score	0.074519 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	644	Shared Neighborhood Hits	5
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ARL3_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.031841 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	257	Shared Neighborhood Hits	23
SwissProt Accessions	P36405	Gene names	ARL3, ARFL3
Domain Architecture
Description	ADP-ribosylation factor-like protein 3.

ARL3_MOUSE
θ value	2.36792 (rank : 40)	NC score	0.032407 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	258	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WUL7	Gene names	Arl3
Domain Architecture
Description	ADP-ribosylation factor-like protein 3.

IP3KA_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.021737 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

RIT2_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.055866 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	272	Shared Neighborhood Hits	23
SwissProt Accessions	P70425, Q3UST1, Q3UUP4, Q8BQT5, Q9QWX5	Gene names	Rit2, Rin, Roc2
Domain Architecture
Description	GTP-binding protein Rit2 (Ras-like protein expressed in neurons) (Ras- like without CAAX protein 2).

ADA15_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.006912 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	324	Shared Neighborhood Hits	2
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

GIMA2_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.183127 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UG22, Q96L25	Gene names	GIMAP2, IMAP2
Domain Architecture
Description	GTPase, IMAP family member 2 (Immunity-associated protein 2) (hIMAP2).

KAD3_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.032935 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UIJ7, Q5VYW6, Q9H576, Q9NPB4	Gene names	AK3, AK3L1, AKL3L
Domain Architecture
Description	GTP:AMP phosphotransferase mitochondrial (EC 2.7.4.10) (Adenylate kinase 3) (AK3) (Adenylate kinase 3 alpha-like 1).

METK2_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.043312 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P31153, Q53SP5	Gene names	MAT2A, AMS2, MATA2
Domain Architecture
Description	S-adenosylmethionine synthetase isoform type-2 (EC 2.5.1.6) (Methionine adenosyltransferase 2) (AdoMet synthetase 2) (Methionine adenosyltransferase II) (MAT-II).

METK2_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.043308 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q3THS6, Q3TL60, Q76LX3	Gene names	Mat2a
Domain Architecture	No domain graphic available
Description	S-adenosylmethionine synthetase isoform type-2 (EC 2.5.1.6) (Methionine adenosyltransferase 2) (AdoMet synthetase 2).

MIRO1_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.078826 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	214	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IXI2, Q6NUR3, Q6P9F8, Q6PJG1, Q6YMW8, Q86UB0, Q8IW28, Q8IXJ7, Q9H067, Q9H9N8, Q9NUZ2	Gene names	RHOT1, ARHT1
Domain Architecture	No domain graphic available
Description	Mitochondrial Rho GTPase 1 (EC 3.6.5.-) (MIRO-1) (hMiro-1) (Ras homolog gene family member T1) (Rac-GTP-binding protein-like protein).

MIRO1_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.078398 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	225	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BG51, Q3TJB7, Q3UGU4, Q5SYC3, Q5SYC6, Q8BLW3, Q8BMH1, Q922N0, Q9D2R1, Q9JKB9	Gene names	Rhot1, Arht1
Domain Architecture	No domain graphic available
Description	Mitochondrial Rho GTPase 1 (EC 3.6.5.-) (MIRO-1) (Ras homolog gene family member T1).

ARL2_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.028035 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	250	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D0J4, Q9WUM1	Gene names	Arl2
Domain Architecture
Description	ADP-ribosylation factor-like protein 2.

EGLN_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.022235 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q63961, Q61520	Gene names	Eng, Edg
Domain Architecture
Description	Endoglin precursor (Cell surface MJ7/18 antigen).

KAD3_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.031534 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTP7, Q3UDN7, Q8BGX5, Q9D7Z1, Q9DB57, Q9DBM5	Gene names	Ak3, Ak3l, Ak3l1, Akl3l
Domain Architecture
Description	GTP:AMP phosphotransferase mitochondrial (EC 2.7.4.10) (Adenylate kinase 3) (AK3) (Adenylate kinase 3 alpha-like 1).

RAB23_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.032938 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	278	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULC3, Q8NI06, Q9P023	Gene names	RAB23
Domain Architecture
Description	Ras-related protein Rab-23.

RIT2_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.055237 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	264	Shared Neighborhood Hits	23
SwissProt Accessions	Q99578, O15295, Q8TD69, Q8WVF6, Q92964	Gene names	RIT2, RIN, ROC2
Domain Architecture
Description	GTP-binding protein Rit2 (Ras-like protein expressed in neurons) (Ras- like without CAAX protein 2).

ARL2_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.026511 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	250	Shared Neighborhood Hits	14
SwissProt Accessions	P36404, Q9BUK8	Gene names	ARL2
Domain Architecture
Description	ADP-ribosylation factor-like protein 2.

MFN2_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.033480 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	O95140, O95572, Q5JXC3, Q5JXC4, Q9H131, Q9NSX8	Gene names	MFN2, CPRP1, KIAA0214
Domain Architecture
Description	Transmembrane GTPase MFN2 (EC 3.6.5.-) (Mitofusin-2).

MFN2_MOUSE
θ value	6.88961 (rank : 57)	NC score	0.033525 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q80U63, Q3V3B8, Q80WP4, Q80XK3, Q8BHF0, Q8BKV5, Q8R535, Q923X2	Gene names	Mfn2, Kiaa0214, Marf
Domain Architecture
Description	Transmembrane GTPase MFN2 (EC 3.6.5.-) (Mitofusin-2) (Hypertension- related protein 1) (Mitochondrial assembly regulatory factor) (HSG protein).

SF01_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.021071 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	287	Shared Neighborhood Hits	3
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.021868 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	240	Shared Neighborhood Hits	3
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

APLP1_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.011017 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	P51693, O00113, Q96A92	Gene names	APLP1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

GNL3_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.096547 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CI11, Q811R9, Q811S8, Q8BK21	Gene names	Gnl3, Ns
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein-like 3 (Nucleolar GTP-binding protein 3) (Nucleostemin).

MFN1_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.030764 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	Q811U4, Q811D5, Q8CEY6, Q99M10, Q9D395	Gene names	Mfn1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1).

OTOAN_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.029368 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K561	Gene names	Otoa
Domain Architecture	No domain graphic available
Description	Otoancorin precursor.

TTDN1_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.020598 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D011	Gene names	Ttdn1
Domain Architecture	No domain graphic available
Description	TTD non-photosensitive 1 protein homolog.

ZN567_HUMAN
θ value	8.99809 (rank : 65)	NC score	-0.001987 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	769	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N184, Q6N044	Gene names	ZNF567
Domain Architecture	No domain graphic available
Description	Zinc finger protein 567.

DIRA3_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.050138 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	241	Shared Neighborhood Hits	18
SwissProt Accessions	O95661	Gene names	DIRAS3, ARHI, NOEY2, RHOI
Domain Architecture
Description	GTP-binding protein Di-Ras3 (Distinct subgroup of the Ras family member 3) (Rho-related GTP-binding protein RhoI).

MIRO2_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.057087 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	228	Shared Neighborhood Hits	20
SwissProt Accessions	Q8JZN7	Gene names	Rhot2, Arht2
Domain Architecture	No domain graphic available
Description	Mitochondrial Rho GTPase 2 (EC 3.6.5.-) (MIRO-2) (Ras homolog gene family member T2).

RR22_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.050009 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	201	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K5A4	Gene names	Rrp22
Domain Architecture	No domain graphic available
Description	Ras-like protein RRP22 (RAS-related protein on chromosome 22 homolog).

Hits sorted by NC score

ERAL_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	O75616, O75617, Q8WUY4, Q96LE2, Q96TC0	Gene names	ERAL1, HERA
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (hERA) (ERA-W) (Conserved ERA-like GTPase) (CEGA).

ERAL_MOUSE
NC score	0.988151 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	48
SwissProt Accessions	Q9CZU4, Q6NV78, Q925U1	Gene names	Eral1
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (ERA-W) (Conserved ERA-like GTPase) (CEGA).

GIMA4_HUMAN
NC score	0.295927 (rank : 3)	θ value	1.29631e-06 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	217	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NUV9	Gene names	GIMAP4, IAN1, IMAP4
Domain Architecture
Description	GTPase, IMAP family member 4 (Immunity-associated protein 4) (Immunity-associated nucleotide 1 protein) (hIAN1).

GIMA4_MOUSE
NC score	0.282234 (rank : 4)	θ value	0.00102713 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q99JY3	Gene names	Gimap4, Ian1, Imap4
Domain Architecture
Description	GTPase, IMAP family member 4 (Immunity-associated protein 4) (Immunity-associated nucleotide 1 protein).

GTPB5_HUMAN
NC score	0.268743 (rank : 5)	θ value	0.00134147 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4K7, Q96I17, Q9NVG9, Q9UFR4	Gene names	GTPBP5
Domain Architecture
Description	Putative GTP-binding protein 5.

GNL1_HUMAN
NC score	0.261418 (rank : 6)	θ value	0.00035302 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	P36915	Gene names	GNL1, HSR1
Domain Architecture
Description	Guanine nucleotide-binding protein-like 1 (GTP-binding protein HSR1).

GNL1_MOUSE
NC score	0.245514 (rank : 7)	θ value	0.00175202 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	P36916	Gene names	Gnl1, Gna-rs1, Mmr1
Domain Architecture
Description	Guanine nucleotide-binding protein-like 1 (GTP-binding protein MMR1).

GIMA7_HUMAN
NC score	0.237272 (rank : 8)	θ value	0.0252991 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	93	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NHV1	Gene names	GIMAP7, IAN7
Domain Architecture	No domain graphic available
Description	GTPase, IMAP family member 7 (Immunity-associated nucleotide 7 protein).

GIMA1_HUMAN
NC score	0.230258 (rank : 9)	θ value	0.0148317 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WWP7, Q8NAZ0	Gene names	GIMAP1, IMAP1
Domain Architecture
Description	GTPase, IMAP family member 1 (Immunity-associated protein 1) (hIMAP1).

GIMA5_HUMAN
NC score	0.225638 (rank : 10)	θ value	0.0961366 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q96F15, Q6IA75, Q96NE4, Q9NUK9	Gene names	GIMAP5, IAN4L1, IMAP3
Domain Architecture
Description	GTPase, IMAP family member 5 (Immunity-associated nucleotide 4-like 1 protein) (Immunity-associated protein 3) (IAN-5).

DRG1_HUMAN
NC score	0.217024 (rank : 11)	θ value	0.0330416 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y295, Q6FGP8, Q8WW69, Q9UGF2	Gene names	DRG1
Domain Architecture
Description	Developmentally-regulated GTP-binding protein 1 (DRG 1).

DRG1_MOUSE
NC score	0.216984 (rank : 12)	θ value	0.0330416 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	P32233	Gene names	Drg1, Drg, Nedd-3, Nedd3
Domain Architecture
Description	Developmentally-regulated GTP-binding protein 1 (DRG 1) (Protein NEDD3) (Neural precursor cell expressed developmentally down-regulated protein 3).

GIMA1_MOUSE
NC score	0.216567 (rank : 13)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	P70224	Gene names	Gimap1, Imap1, Imap38
Domain Architecture	No domain graphic available
Description	GTPase, IMAP family member 1 (Immunity-associated protein 1) (Immune- associated protein 38) (IAP38).

DRG2_MOUSE
NC score	0.204824 (rank : 14)	θ value	0.0330416 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QXB9	Gene names	Drg2
Domain Architecture
Description	Developmentally-regulated GTP-binding protein 2 (DRG 2).

GIMA3_MOUSE
NC score	0.203874 (rank : 15)	θ value	0.21417 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	Q99MI6, Q4VBX0, Q549W4, Q8CF04	Gene names	Gimap3, Ian4
Domain Architecture
Description	GTPase, IMAP family member 3 (Immunity-associated nucleotide 4 protein).

DRG2_HUMAN
NC score	0.203694 (rank : 16)	θ value	0.0563607 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	P55039, Q9BWB2	Gene names	DRG2
Domain Architecture
Description	Developmentally-regulated GTP-binding protein 2 (DRG 2).

GIMA5_MOUSE
NC score	0.191107 (rank : 17)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	35	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BWF2, Q501L7, Q549X3	Gene names	Gimap5, Ian4l1, Imap3
Domain Architecture
Description	GTPase, IMAP family member 5 (Immunity-associated nucleotide 4-like 1 protein) (Immunity-associated protein 3).

GIMA2_HUMAN
NC score	0.183127 (rank : 18)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UG22, Q96L25	Gene names	GIMAP2, IMAP2
Domain Architecture
Description	GTPase, IMAP family member 2 (Immunity-associated protein 2) (hIMAP2).

NOG1_HUMAN
NC score	0.177312 (rank : 19)	θ value	0.0431538 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZE4, O95446, Q9NVJ8	Gene names	GTPBP4, CRFG, NOG1
Domain Architecture
Description	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB).

NOG1_MOUSE
NC score	0.176299 (rank : 20)	θ value	0.0736092 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	93	Shared Neighborhood Hits	13
SwissProt Accessions	Q99ME9, Q99K16, Q99P78, Q9CT02	Gene names	Gtpbp4, Crfg, Nog1
Domain Architecture
Description	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB).

GNL3_HUMAN
NC score	0.137479 (rank : 21)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	83	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BVP2, Q96SV6, Q96SV7, Q9UJY0	Gene names	GNL3, E2IG3, NS
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein-like 3 (Nucleolar GTP-binding protein 3) (Nucleostemin) (E2-induced gene 3-protein) (Novel nucleolar protein 47) (NNP47).

NOG2_MOUSE
NC score	0.133719 (rank : 22)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LH1, Q8BIF8	Gene names	Gnl2
Domain Architecture	No domain graphic available
Description	Nucleolar GTP-binding protein 2.

NOG2_HUMAN
NC score	0.132537 (rank : 23)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q13823, Q9BWN7	Gene names	GNL2, NGP1
Domain Architecture
Description	Nucleolar GTP-binding protein 2 (Autoantigen NGP-1).

GEM_MOUSE
NC score	0.105403 (rank : 24)	θ value	0.125558 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	233	Shared Neighborhood Hits	22
SwissProt Accessions	P55041, Q8JZS1	Gene names	Gem, Kir
Domain Architecture
Description	GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR).

REM1_HUMAN
NC score	0.104807 (rank : 25)	θ value	0.0431538 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	247	Shared Neighborhood Hits	22
SwissProt Accessions	O75628, Q9NP57	Gene names	REM1, GES, REM
Domain Architecture
Description	GTP-binding protein REM 1 (Rad and Gem-like GTP-binding protein 1) (GTPase-regulating endothelial cell sprouting).

RAD_MOUSE
NC score	0.103207 (rank : 26)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	216	Shared Neighborhood Hits	22
SwissProt Accessions	O88667	Gene names	Rrad
Domain Architecture
Description	GTP-binding protein RAD.

GEM_HUMAN
NC score	0.102256 (rank : 27)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	238	Shared Neighborhood Hits	22
SwissProt Accessions	P55040	Gene names	GEM, KIR
Domain Architecture
Description	GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein) (RAS-like protein KIR).

TP53B_HUMAN
NC score	0.099117 (rank : 28)	θ value	0.0736092 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	413	Shared Neighborhood Hits	4
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

REM1_MOUSE
NC score	0.097216 (rank : 29)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	255	Shared Neighborhood Hits	22
SwissProt Accessions	O35929	Gene names	Rem1, Rem
Domain Architecture
Description	GTP-binding protein REM 1 (Rad and Gem-like GTP-binding protein 1).

GNL3_MOUSE
NC score	0.096547 (rank : 30)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CI11, Q811R9, Q811S8, Q8BK21	Gene names	Gnl3, Ns
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein-like 3 (Nucleolar GTP-binding protein 3) (Nucleostemin).

RAD_HUMAN
NC score	0.094415 (rank : 31)	θ value	0.365318 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	224	Shared Neighborhood Hits	21
SwissProt Accessions	P55042, Q96F39	Gene names	RRAD, RAD
Domain Architecture
Description	GTP-binding protein RAD (RAS associated with diabetes) (RAD1).

REM2_MOUSE
NC score	0.091884 (rank : 32)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	238	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VEL9, Q8BPB1	Gene names	Rem2
Domain Architecture	No domain graphic available
Description	GTP-binding protein REM 2 (Rad and Gem-like GTP-binding protein 2).

REM2_HUMAN
NC score	0.091201 (rank : 33)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	237	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IYK8, Q8N8R8	Gene names	REM2
Domain Architecture	No domain graphic available
Description	GTP-binding protein REM 2 (Rad and Gem-like GTP-binding protein 2).

MIRO2_HUMAN
NC score	0.080353 (rank : 34)	θ value	0.47712 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	226	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IXI1, Q8NF53, Q96C13, Q96S17, Q9BT60, Q9H7M8	Gene names	RHOT2, ARHT2
Domain Architecture	No domain graphic available
Description	Mitochondrial Rho GTPase 2 (EC 3.6.5.-) (MIRO-2) (hMiro-2) (Ras homolog gene family member T2).

MIRO1_HUMAN
NC score	0.078826 (rank : 35)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	214	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IXI2, Q6NUR3, Q6P9F8, Q6PJG1, Q6YMW8, Q86UB0, Q8IW28, Q8IXJ7, Q9H067, Q9H9N8, Q9NUZ2	Gene names	RHOT1, ARHT1
Domain Architecture	No domain graphic available
Description	Mitochondrial Rho GTPase 1 (EC 3.6.5.-) (MIRO-1) (hMiro-1) (Ras homolog gene family member T1) (Rac-GTP-binding protein-like protein).

MIRO1_MOUSE
NC score	0.078398 (rank : 36)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	225	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BG51, Q3TJB7, Q3UGU4, Q5SYC3, Q5SYC6, Q8BLW3, Q8BMH1, Q922N0, Q9D2R1, Q9JKB9	Gene names	Rhot1, Arht1
Domain Architecture	No domain graphic available
Description	Mitochondrial Rho GTPase 1 (EC 3.6.5.-) (MIRO-1) (Ras homolog gene family member T1).

TP53B_MOUSE
NC score	0.074519 (rank : 37)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	644	Shared Neighborhood Hits	5
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

RIT1_HUMAN
NC score	0.062876 (rank : 38)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	265	Shared Neighborhood Hits	24
SwissProt Accessions	Q92963, O00646, O00720	Gene names	RIT1, RIBB, RIT, ROC1
Domain Architecture
Description	GTP-binding protein Rit1 (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1).

RIT1_MOUSE
NC score	0.060051 (rank : 39)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	266	Shared Neighborhood Hits	23
SwissProt Accessions	P70426	Gene names	Rit1, Rit
Domain Architecture
Description	GTP-binding protein Rit1 (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1).

RALB_HUMAN
NC score	0.057784 (rank : 40)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	274	Shared Neighborhood Hits	23
SwissProt Accessions	P11234	Gene names	RALB
Domain Architecture
Description	Ras-related protein Ral-B.

RBM16_HUMAN
NC score	0.057424 (rank : 41)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	300	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

MIRO2_MOUSE
NC score	0.057087 (rank : 42)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	228	Shared Neighborhood Hits	20
SwissProt Accessions	Q8JZN7	Gene names	Rhot2, Arht2
Domain Architecture	No domain graphic available
Description	Mitochondrial Rho GTPase 2 (EC 3.6.5.-) (MIRO-2) (Ras homolog gene family member T2).

RALB_MOUSE
NC score	0.056214 (rank : 43)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	274	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JIW9, Q3TVS5	Gene names	Ralb
Domain Architecture
Description	Ras-related protein Ral-B.

RIT2_MOUSE
NC score	0.055866 (rank : 44)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	272	Shared Neighborhood Hits	23
SwissProt Accessions	P70425, Q3UST1, Q3UUP4, Q8BQT5, Q9QWX5	Gene names	Rit2, Rin, Roc2
Domain Architecture
Description	GTP-binding protein Rit2 (Ras-like protein expressed in neurons) (Ras- like without CAAX protein 2).

RIT2_HUMAN
NC score	0.055237 (rank : 45)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	264	Shared Neighborhood Hits	23
SwissProt Accessions	Q99578, O15295, Q8TD69, Q8WVF6, Q92964	Gene names	RIT2, RIN, ROC2
Domain Architecture
Description	GTP-binding protein Rit2 (Ras-like protein expressed in neurons) (Ras- like without CAAX protein 2).

DIRA3_HUMAN
NC score	0.050138 (rank : 46)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	241	Shared Neighborhood Hits	18
SwissProt Accessions	O95661	Gene names	DIRAS3, ARHI, NOEY2, RHOI
Domain Architecture
Description	GTP-binding protein Di-Ras3 (Distinct subgroup of the Ras family member 3) (Rho-related GTP-binding protein RhoI).

RR22_MOUSE
NC score	0.050009 (rank : 47)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	201	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K5A4	Gene names	Rrp22
Domain Architecture	No domain graphic available
Description	Ras-like protein RRP22 (RAS-related protein on chromosome 22 homolog).

METK2_HUMAN
NC score	0.043312 (rank : 48)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P31153, Q53SP5	Gene names	MAT2A, AMS2, MATA2
Domain Architecture
Description	S-adenosylmethionine synthetase isoform type-2 (EC 2.5.1.6) (Methionine adenosyltransferase 2) (AdoMet synthetase 2) (Methionine adenosyltransferase II) (MAT-II).

METK2_MOUSE
NC score	0.043308 (rank : 49)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q3THS6, Q3TL60, Q76LX3	Gene names	Mat2a
Domain Architecture	No domain graphic available
Description	S-adenosylmethionine synthetase isoform type-2 (EC 2.5.1.6) (Methionine adenosyltransferase 2) (AdoMet synthetase 2).

MFN2_MOUSE
NC score	0.033525 (rank : 50)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q80U63, Q3V3B8, Q80WP4, Q80XK3, Q8BHF0, Q8BKV5, Q8R535, Q923X2	Gene names	Mfn2, Kiaa0214, Marf
Domain Architecture
Description	Transmembrane GTPase MFN2 (EC 3.6.5.-) (Mitofusin-2) (Hypertension- related protein 1) (Mitochondrial assembly regulatory factor) (HSG protein).

MFN2_HUMAN
NC score	0.033480 (rank : 51)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	O95140, O95572, Q5JXC3, Q5JXC4, Q9H131, Q9NSX8	Gene names	MFN2, CPRP1, KIAA0214
Domain Architecture
Description	Transmembrane GTPase MFN2 (EC 3.6.5.-) (Mitofusin-2).

RAB23_HUMAN
NC score	0.032938 (rank : 52)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	278	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULC3, Q8NI06, Q9P023	Gene names	RAB23
Domain Architecture
Description	Ras-related protein Rab-23.

KAD3_HUMAN
NC score	0.032935 (rank : 53)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UIJ7, Q5VYW6, Q9H576, Q9NPB4	Gene names	AK3, AK3L1, AKL3L
Domain Architecture
Description	GTP:AMP phosphotransferase mitochondrial (EC 2.7.4.10) (Adenylate kinase 3) (AK3) (Adenylate kinase 3 alpha-like 1).

ARL3_MOUSE
NC score	0.032407 (rank : 54)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	258	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WUL7	Gene names	Arl3
Domain Architecture
Description	ADP-ribosylation factor-like protein 3.

ARL3_HUMAN
NC score	0.031841 (rank : 55)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	257	Shared Neighborhood Hits	23
SwissProt Accessions	P36405	Gene names	ARL3, ARFL3
Domain Architecture
Description	ADP-ribosylation factor-like protein 3.

KAD3_MOUSE
NC score	0.031534 (rank : 56)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTP7, Q3UDN7, Q8BGX5, Q9D7Z1, Q9DB57, Q9DBM5	Gene names	Ak3, Ak3l, Ak3l1, Akl3l
Domain Architecture
Description	GTP:AMP phosphotransferase mitochondrial (EC 2.7.4.10) (Adenylate kinase 3) (AK3) (Adenylate kinase 3 alpha-like 1).

MFN1_MOUSE
NC score	0.030764 (rank : 57)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	55	Shared Neighborhood Hits	8
SwissProt Accessions	Q811U4, Q811D5, Q8CEY6, Q99M10, Q9D395	Gene names	Mfn1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1).

OTOAN_MOUSE
NC score	0.029368 (rank : 58)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K561	Gene names	Otoa
Domain Architecture	No domain graphic available
Description	Otoancorin precursor.

ARL2_MOUSE
NC score	0.028035 (rank : 59)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	250	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D0J4, Q9WUM1	Gene names	Arl2
Domain Architecture
Description	ADP-ribosylation factor-like protein 2.

ARL2_HUMAN
NC score	0.026511 (rank : 60)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	250	Shared Neighborhood Hits	14
SwissProt Accessions	P36404, Q9BUK8	Gene names	ARL2
Domain Architecture
Description	ADP-ribosylation factor-like protein 2.

EGLN_MOUSE
NC score	0.022235 (rank : 61)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q63961, Q61520	Gene names	Eng, Edg
Domain Architecture
Description	Endoglin precursor (Cell surface MJ7/18 antigen).

SF01_MOUSE
NC score	0.021868 (rank : 62)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	240	Shared Neighborhood Hits	3
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

IP3KA_HUMAN
NC score	0.021737 (rank : 63)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

SF01_HUMAN
NC score	0.021071 (rank : 64)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	287	Shared Neighborhood Hits	3
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

TTDN1_MOUSE
NC score	0.020598 (rank : 65)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D011	Gene names	Ttdn1
Domain Architecture	No domain graphic available
Description	TTD non-photosensitive 1 protein homolog.

APLP1_HUMAN
NC score	0.011017 (rank : 66)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	P51693, O00113, Q96A92	Gene names	APLP1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

ADA15_MOUSE
NC score	0.006912 (rank : 67)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	324	Shared Neighborhood Hits	2
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ZN567_HUMAN
NC score	-0.001987 (rank : 68)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	769	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N184, Q6N044	Gene names	ZNF567
Domain Architecture	No domain graphic available
Description	Zinc finger protein 567.