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Network neighborhood for query Sequence : NOG2_MOUSE

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NOG2_MOUSE
SwissProt Accessions	Q99LH1, Q8BIF8	Gene names	Gnl2
Domain Architecture	No domain graphic available
Description	Nucleolar GTP-binding protein 2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NOG2_HUMAN
θ value	0 (rank : 1)	NC score	0.952292 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	117	Shared Neighborhood Hits	24
SwissProt Accessions	Q13823, Q9BWN7	Gene names	GNL2, NGP1
Domain Architecture
Description	Nucleolar GTP-binding protein 2 (Autoantigen NGP-1).

NOG2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q99LH1, Q8BIF8	Gene names	Gnl2
Domain Architecture	No domain graphic available
Description	Nucleolar GTP-binding protein 2.

GNL3_HUMAN
θ value	1.16164e-39 (rank : 3)	NC score	0.777967 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	83	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BVP2, Q96SV6, Q96SV7, Q9UJY0	Gene names	GNL3, E2IG3, NS
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein-like 3 (Nucleolar GTP-binding protein 3) (Nucleostemin) (E2-induced gene 3-protein) (Novel nucleolar protein 47) (NNP47).

GNL3_MOUSE
θ value	1.16164e-39 (rank : 4)	NC score	0.770836 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	99	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CI11, Q811R9, Q811S8, Q8BK21	Gene names	Gnl3, Ns
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein-like 3 (Nucleolar GTP-binding protein 3) (Nucleostemin).

GNL1_HUMAN
θ value	1.2105e-12 (rank : 5)	NC score	0.543342 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	P36915	Gene names	GNL1, HSR1
Domain Architecture
Description	Guanine nucleotide-binding protein-like 1 (GTP-binding protein HSR1).

GNL1_MOUSE
θ value	2.0648e-12 (rank : 6)	NC score	0.539699 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	P36916	Gene names	Gnl1, Gna-rs1, Mmr1
Domain Architecture
Description	Guanine nucleotide-binding protein-like 1 (GTP-binding protein MMR1).

IWS1_MOUSE
θ value	0.0431538 (rank : 7)	NC score	0.051377 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	1258	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DRG1_HUMAN
θ value	0.0563607 (rank : 8)	NC score	0.149749 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y295, Q6FGP8, Q8WW69, Q9UGF2	Gene names	DRG1
Domain Architecture
Description	Developmentally-regulated GTP-binding protein 1 (DRG 1).

DRG1_MOUSE
θ value	0.0563607 (rank : 9)	NC score	0.149696 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	P32233	Gene names	Drg1, Drg, Nedd-3, Nedd3
Domain Architecture
Description	Developmentally-regulated GTP-binding protein 1 (DRG 1) (Protein NEDD3) (Neural precursor cell expressed developmentally down-regulated protein 3).

SEC63_MOUSE
θ value	0.0961366 (rank : 10)	NC score	0.058665 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	601	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

CT2NL_HUMAN
θ value	0.125558 (rank : 11)	NC score	0.043078 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	1059	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

NOG1_HUMAN
θ value	0.163984 (rank : 12)	NC score	0.125570 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZE4, O95446, Q9NVJ8	Gene names	GTPBP4, CRFG, NOG1
Domain Architecture
Description	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB).

NOG1_MOUSE
θ value	0.163984 (rank : 13)	NC score	0.126593 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	93	Shared Neighborhood Hits	14
SwissProt Accessions	Q99ME9, Q99K16, Q99P78, Q9CT02	Gene names	Gtpbp4, Crfg, Nog1
Domain Architecture
Description	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB).

PLCB4_HUMAN
θ value	0.163984 (rank : 14)	NC score	0.034186 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	658	Shared Neighborhood Hits	25
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

NALP5_MOUSE
θ value	0.21417 (rank : 15)	NC score	0.027431 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	560	Shared Neighborhood Hits	13
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

CN145_HUMAN
θ value	0.279714 (rank : 16)	NC score	0.026646 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	1196	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

MINT_MOUSE
θ value	0.279714 (rank : 17)	NC score	0.046005 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	1514	Shared Neighborhood Hits	25
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SYNE2_HUMAN
θ value	0.279714 (rank : 18)	NC score	0.025994 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	1323	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

DMN_HUMAN
θ value	0.365318 (rank : 19)	NC score	0.027298 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	690	Shared Neighborhood Hits	24
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

IWS1_HUMAN
θ value	0.365318 (rank : 20)	NC score	0.053595 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	1241	Shared Neighborhood Hits	28
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MINT_HUMAN
θ value	0.365318 (rank : 21)	NC score	0.051387 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	1291	Shared Neighborhood Hits	30
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CT2NL_MOUSE
θ value	0.47712 (rank : 22)	NC score	0.045309 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	902	Shared Neighborhood Hits	23
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

TGON2_HUMAN
θ value	0.47712 (rank : 23)	NC score	0.031685 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	1037	Shared Neighborhood Hits	19
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

EPC2_MOUSE
θ value	0.62314 (rank : 24)	NC score	0.031069 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0I4, Q3URX9, Q80Y70, Q8BXC5	Gene names	Epc2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

ERAL_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.133719 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	O75616, O75617, Q8WUY4, Q96LE2, Q96TC0	Gene names	ERAL1, HERA
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (hERA) (ERA-W) (Conserved ERA-like GTPase) (CEGA).

LIPA2_MOUSE
θ value	0.813845 (rank : 26)	NC score	0.033397 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	1282	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

TRIPB_HUMAN
θ value	0.813845 (rank : 27)	NC score	0.022896 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	1587	Shared Neighborhood Hits	25
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ERAL_MOUSE
θ value	1.06291 (rank : 28)	NC score	0.127101 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	60	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CZU4, Q6NV78, Q925U1	Gene names	Eral1
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (ERA-W) (Conserved ERA-like GTPase) (CEGA).

MRCKA_HUMAN
θ value	1.06291 (rank : 29)	NC score	0.009573 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	1999	Shared Neighborhood Hits	26
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

MYO5A_HUMAN
θ value	1.06291 (rank : 30)	NC score	0.017605 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	1092	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

RPTN_MOUSE
θ value	1.06291 (rank : 31)	NC score	0.022546 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	650	Shared Neighborhood Hits	15
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SEC63_HUMAN
θ value	1.06291 (rank : 32)	NC score	0.057415 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	586	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

CBP_MOUSE
θ value	1.38821 (rank : 33)	NC score	0.032225 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	1051	Shared Neighborhood Hits	15
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

NEB2_MOUSE
θ value	1.38821 (rank : 34)	NC score	0.028623 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	889	Shared Neighborhood Hits	19
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

ZN184_HUMAN
θ value	1.38821 (rank : 35)	NC score	0.000061 (rank : 72)
Query Neighborhood Hits	71	Target Neighborhood Hits	811	Shared Neighborhood Hits	3
SwissProt Accessions	Q99676, O60792, Q8TBA9	Gene names	ZNF184
Domain Architecture
Description	Zinc finger protein 184.

NEB2_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.027422 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	883	Shared Neighborhood Hits	19
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEST_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.036136 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	1305	Shared Neighborhood Hits	35
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

RBBP5_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.019644 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	372	Shared Neighborhood Hits	5
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

RN168_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.030617 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	440	Shared Neighborhood Hits	14
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

CE005_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.013623 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	238	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

TITIN_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.007808 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	2923	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CBP_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.031368 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	941	Shared Neighborhood Hits	16
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DAF1_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.011940 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	204	Shared Neighborhood Hits	8
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

DRG2_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.082461 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	P55039, Q9BWB2	Gene names	DRG2
Domain Architecture
Description	Developmentally-regulated GTP-binding protein 2 (DRG 2).

HMMR_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.022482 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	1082	Shared Neighborhood Hits	26
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

LTB1L_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.008089 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	553	Shared Neighborhood Hits	9
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.007344 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	502	Shared Neighborhood Hits	5
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NEK1_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.002987 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	1311	Shared Neighborhood Hits	16
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

ADDA_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.016543 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	198	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

BAZ2A_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.017624 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	780	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CCD50_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.023236 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	237	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CYLN2_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.016961 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	1004	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

IF2M_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.017108 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	183	Shared Neighborhood Hits	5
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

KCNQ2_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.008132 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

MYO5A_MOUSE
θ value	5.27518 (rank : 55)	NC score	0.018737 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	1117	Shared Neighborhood Hits	31
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

NOP14_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.061116 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	573	Shared Neighborhood Hits	25
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

ZN447_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.003027 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	899	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

DRG2_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.077581 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QXB9	Gene names	Drg2
Domain Architecture
Description	Developmentally-regulated GTP-binding protein 2 (DRG 2).

FGD6_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.009471 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	282	Shared Neighborhood Hits	6
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

MDC1_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.020023 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	1446	Shared Neighborhood Hits	28
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYCD_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.011745 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

RFC1_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.023544 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	352	Shared Neighborhood Hits	18
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

SDPR_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.029822 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	485	Shared Neighborhood Hits	19
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

WHRN_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.009458 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	412	Shared Neighborhood Hits	9
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

BMP4_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.004338 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	P12644, Q9UM80	Gene names	BMP4, BMP2B, DVR4
Domain Architecture
Description	Bone morphogenetic protein 4 precursor (BMP-4) (BMP-2B).

C8AP2_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.016575 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	548	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CEP55_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.020791 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	504	Shared Neighborhood Hits	17
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

CIR_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.032059 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	249	Shared Neighborhood Hits	17
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

EP300_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.029765 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	821	Shared Neighborhood Hits	21
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

HMMR_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.018039 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	1178	Shared Neighborhood Hits	26
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

SHAN2_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.009170 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	446	Shared Neighborhood Hits	7
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

VPS72_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.052040 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	286	Shared Neighborhood Hits	14
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

Hits sorted by NC score

NOG2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q99LH1, Q8BIF8	Gene names	Gnl2
Domain Architecture	No domain graphic available
Description	Nucleolar GTP-binding protein 2.

NOG2_HUMAN
NC score	0.952292 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	117	Shared Neighborhood Hits	24
SwissProt Accessions	Q13823, Q9BWN7	Gene names	GNL2, NGP1
Domain Architecture
Description	Nucleolar GTP-binding protein 2 (Autoantigen NGP-1).

GNL3_HUMAN
NC score	0.777967 (rank : 3)	θ value	1.16164e-39 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	83	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BVP2, Q96SV6, Q96SV7, Q9UJY0	Gene names	GNL3, E2IG3, NS
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein-like 3 (Nucleolar GTP-binding protein 3) (Nucleostemin) (E2-induced gene 3-protein) (Novel nucleolar protein 47) (NNP47).

GNL3_MOUSE
NC score	0.770836 (rank : 4)	θ value	1.16164e-39 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	99	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CI11, Q811R9, Q811S8, Q8BK21	Gene names	Gnl3, Ns
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein-like 3 (Nucleolar GTP-binding protein 3) (Nucleostemin).

GNL1_HUMAN
NC score	0.543342 (rank : 5)	θ value	1.2105e-12 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	P36915	Gene names	GNL1, HSR1
Domain Architecture
Description	Guanine nucleotide-binding protein-like 1 (GTP-binding protein HSR1).

GNL1_MOUSE
NC score	0.539699 (rank : 6)	θ value	2.0648e-12 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	P36916	Gene names	Gnl1, Gna-rs1, Mmr1
Domain Architecture
Description	Guanine nucleotide-binding protein-like 1 (GTP-binding protein MMR1).

DRG1_HUMAN
NC score	0.149749 (rank : 7)	θ value	0.0563607 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y295, Q6FGP8, Q8WW69, Q9UGF2	Gene names	DRG1
Domain Architecture
Description	Developmentally-regulated GTP-binding protein 1 (DRG 1).

DRG1_MOUSE
NC score	0.149696 (rank : 8)	θ value	0.0563607 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	P32233	Gene names	Drg1, Drg, Nedd-3, Nedd3
Domain Architecture
Description	Developmentally-regulated GTP-binding protein 1 (DRG 1) (Protein NEDD3) (Neural precursor cell expressed developmentally down-regulated protein 3).

ERAL_HUMAN
NC score	0.133719 (rank : 9)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	O75616, O75617, Q8WUY4, Q96LE2, Q96TC0	Gene names	ERAL1, HERA
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (hERA) (ERA-W) (Conserved ERA-like GTPase) (CEGA).

ERAL_MOUSE
NC score	0.127101 (rank : 10)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	60	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CZU4, Q6NV78, Q925U1	Gene names	Eral1
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (ERA-W) (Conserved ERA-like GTPase) (CEGA).

NOG1_MOUSE
NC score	0.126593 (rank : 11)	θ value	0.163984 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	93	Shared Neighborhood Hits	14
SwissProt Accessions	Q99ME9, Q99K16, Q99P78, Q9CT02	Gene names	Gtpbp4, Crfg, Nog1
Domain Architecture
Description	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB).

NOG1_HUMAN
NC score	0.125570 (rank : 12)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZE4, O95446, Q9NVJ8	Gene names	GTPBP4, CRFG, NOG1
Domain Architecture
Description	Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB).

DRG2_HUMAN
NC score	0.082461 (rank : 13)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	P55039, Q9BWB2	Gene names	DRG2
Domain Architecture
Description	Developmentally-regulated GTP-binding protein 2 (DRG 2).

DRG2_MOUSE
NC score	0.077581 (rank : 14)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QXB9	Gene names	Drg2
Domain Architecture
Description	Developmentally-regulated GTP-binding protein 2 (DRG 2).

NOP14_HUMAN
NC score	0.061116 (rank : 15)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	573	Shared Neighborhood Hits	25
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

SEC63_MOUSE
NC score	0.058665 (rank : 16)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	601	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_HUMAN
NC score	0.057415 (rank : 17)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	586	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

IWS1_HUMAN
NC score	0.053595 (rank : 18)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	1241	Shared Neighborhood Hits	28
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

VPS72_MOUSE
NC score	0.052040 (rank : 19)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	71	Target Neighborhood Hits	286	Shared Neighborhood Hits	14
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

MINT_HUMAN
NC score	0.051387 (rank : 20)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	1291	Shared Neighborhood Hits	30
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

IWS1_MOUSE
NC score	0.051377 (rank : 21)	θ value	0.0431538 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	1258	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MINT_MOUSE
NC score	0.046005 (rank : 22)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	1514	Shared Neighborhood Hits	25
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CT2NL_MOUSE
NC score	0.045309 (rank : 23)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	902	Shared Neighborhood Hits	23
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CT2NL_HUMAN
NC score	0.043078 (rank : 24)	θ value	0.125558 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	1059	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

NEST_HUMAN
NC score	0.036136 (rank : 25)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	1305	Shared Neighborhood Hits	35
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PLCB4_HUMAN
NC score	0.034186 (rank : 26)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	658	Shared Neighborhood Hits	25
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

LIPA2_MOUSE
NC score	0.033397 (rank : 27)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	1282	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

CBP_MOUSE
NC score	0.032225 (rank : 28)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	1051	Shared Neighborhood Hits	15
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CIR_HUMAN
NC score	0.032059 (rank : 29)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	249	Shared Neighborhood Hits	17
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

TGON2_HUMAN
NC score	0.031685 (rank : 30)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	1037	Shared Neighborhood Hits	19
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CBP_HUMAN
NC score	0.031368 (rank : 31)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	941	Shared Neighborhood Hits	16
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

EPC2_MOUSE
NC score	0.031069 (rank : 32)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0I4, Q3URX9, Q80Y70, Q8BXC5	Gene names	Epc2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

RN168_MOUSE
NC score	0.030617 (rank : 33)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	440	Shared Neighborhood Hits	14
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

SDPR_MOUSE
NC score	0.029822 (rank : 34)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	485	Shared Neighborhood Hits	19
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

EP300_HUMAN
NC score	0.029765 (rank : 35)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	821	Shared Neighborhood Hits	21
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

NEB2_MOUSE
NC score	0.028623 (rank : 36)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	889	Shared Neighborhood Hits	19
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NALP5_MOUSE
NC score	0.027431 (rank : 37)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	560	Shared Neighborhood Hits	13
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NEB2_HUMAN
NC score	0.027422 (rank : 38)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	883	Shared Neighborhood Hits	19
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

DMN_HUMAN
NC score	0.027298 (rank : 39)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	690	Shared Neighborhood Hits	24
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

CN145_HUMAN
NC score	0.026646 (rank : 40)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	1196	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

SYNE2_HUMAN
NC score	0.025994 (rank : 41)	θ value	0.279714 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	1323	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

RFC1_HUMAN
NC score	0.023544 (rank : 42)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	352	Shared Neighborhood Hits	18
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

CCD50_HUMAN
NC score	0.023236 (rank : 43)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	237	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

TRIPB_HUMAN
NC score	0.022896 (rank : 44)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	1587	Shared Neighborhood Hits	25
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

RPTN_MOUSE
NC score	0.022546 (rank : 45)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	650	Shared Neighborhood Hits	15
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

HMMR_HUMAN
NC score	0.022482 (rank : 46)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	1082	Shared Neighborhood Hits	26
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

CEP55_HUMAN
NC score	0.020791 (rank : 47)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	504	Shared Neighborhood Hits	17
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

MDC1_HUMAN
NC score	0.020023 (rank : 48)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	1446	Shared Neighborhood Hits	28
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

RBBP5_HUMAN
NC score	0.019644 (rank : 49)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	372	Shared Neighborhood Hits	5
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

MYO5A_MOUSE
NC score	0.018737 (rank : 50)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	1117	Shared Neighborhood Hits	31
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

HMMR_MOUSE
NC score	0.018039 (rank : 51)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	1178	Shared Neighborhood Hits	26
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

BAZ2A_HUMAN
NC score	0.017624 (rank : 52)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	780	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

MYO5A_HUMAN
NC score	0.017605 (rank : 53)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	1092	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

IF2M_MOUSE
NC score	0.017108 (rank : 54)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	183	Shared Neighborhood Hits	5
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

CYLN2_HUMAN
NC score	0.016961 (rank : 55)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	1004	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

C8AP2_HUMAN
NC score	0.016575 (rank : 56)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	548	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

ADDA_MOUSE
NC score	0.016543 (rank : 57)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	198	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

CE005_MOUSE
NC score	0.013623 (rank : 58)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	238	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

DAF1_MOUSE
NC score	0.011940 (rank : 59)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	204	Shared Neighborhood Hits	8
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

MYCD_HUMAN
NC score	0.011745 (rank : 60)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

MRCKA_HUMAN
NC score	0.009573 (rank : 61)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	1999	Shared Neighborhood Hits	26
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

FGD6_MOUSE
NC score	0.009471 (rank : 62)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	282	Shared Neighborhood Hits	6
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

WHRN_MOUSE
NC score	0.009458 (rank : 63)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	412	Shared Neighborhood Hits	9
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

SHAN2_MOUSE
NC score	0.009170 (rank : 64)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	446	Shared Neighborhood Hits	7
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

KCNQ2_MOUSE
NC score	0.008132 (rank : 65)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

LTB1L_HUMAN
NC score	0.008089 (rank : 66)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	553	Shared Neighborhood Hits	9
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

TITIN_HUMAN
NC score	0.007808 (rank : 67)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	2923	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

LTB1S_HUMAN
NC score	0.007344 (rank : 68)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	502	Shared Neighborhood Hits	5
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

BMP4_HUMAN
NC score	0.004338 (rank : 69)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	P12644, Q9UM80	Gene names	BMP4, BMP2B, DVR4
Domain Architecture
Description	Bone morphogenetic protein 4 precursor (BMP-4) (BMP-2B).

ZN447_HUMAN
NC score	0.003027 (rank : 70)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	899	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TBC5, Q9BRK7, Q9H9A0	Gene names	ZNF447
Domain Architecture	No domain graphic available
Description	Zinc finger protein 447.

NEK1_MOUSE
NC score	0.002987 (rank : 71)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	1311	Shared Neighborhood Hits	16
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

ZN184_HUMAN
NC score	0.000061 (rank : 72)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	811	Shared Neighborhood Hits	3
SwissProt Accessions	Q99676, O60792, Q8TBA9	Gene names	ZNF184
Domain Architecture
Description	Zinc finger protein 184.