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Network neighborhood for query Sequence : E41L5_HUMAN

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E41L5_HUMAN
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

E41L5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	76	Target Neighborhood Hits	76	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LB_HUMAN
θ value	3.1544e-162 (rank : 2)	NC score	0.990791 (rank : 3)
Query Neighborhood Hits	76	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

E41LB_MOUSE
θ value	2.33935e-157 (rank : 3)	NC score	0.993443 (rank : 2)
Query Neighborhood Hits	76	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

E41L2_HUMAN
θ value	7.44272e-79 (rank : 4)	NC score	0.948939 (rank : 14)
Query Neighborhood Hits	76	Target Neighborhood Hits	287	Shared Neighborhood Hits	48
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41LA_HUMAN
θ value	5.33382e-77 (rank : 5)	NC score	0.972152 (rank : 6)
Query Neighborhood Hits	76	Target Neighborhood Hits	87	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41L3_MOUSE
θ value	3.45727e-76 (rank : 6)	NC score	0.952271 (rank : 13)
Query Neighborhood Hits	76	Target Neighborhood Hits	250	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L1_HUMAN
θ value	7.70199e-76 (rank : 7)	NC score	0.958107 (rank : 11)
Query Neighborhood Hits	76	Target Neighborhood Hits	180	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L2_MOUSE
θ value	7.70199e-76 (rank : 8)	NC score	0.926453 (rank : 15)
Query Neighborhood Hits	76	Target Neighborhood Hits	459	Shared Neighborhood Hits	49
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L1_MOUSE
θ value	8.51556e-75 (rank : 9)	NC score	0.963039 (rank : 9)
Query Neighborhood Hits	76	Target Neighborhood Hits	106	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L3_HUMAN
θ value	8.51556e-75 (rank : 10)	NC score	0.965636 (rank : 8)
Query Neighborhood Hits	76	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

41_HUMAN
θ value	1.60597e-73 (rank : 11)	NC score	0.959913 (rank : 10)
Query Neighborhood Hits	76	Target Neighborhood Hits	157	Shared Neighborhood Hits	49
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

E41LA_MOUSE
θ value	2.73936e-73 (rank : 12)	NC score	0.972318 (rank : 5)
Query Neighborhood Hits	76	Target Neighborhood Hits	85	Shared Neighborhood Hits	48
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

PTN4_HUMAN
θ value	6.7473e-72 (rank : 13)	NC score	0.681309 (rank : 32)
Query Neighborhood Hits	76	Target Neighborhood Hits	303	Shared Neighborhood Hits	47
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

41_MOUSE
θ value	1.96316e-71 (rank : 14)	NC score	0.957170 (rank : 12)
Query Neighborhood Hits	76	Target Neighborhood Hits	184	Shared Neighborhood Hits	49
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

FRMD5_HUMAN
θ value	4.52582e-68 (rank : 15)	NC score	0.970820 (rank : 7)
Query Neighborhood Hits	76	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_MOUSE
θ value	5.91091e-68 (rank : 16)	NC score	0.972856 (rank : 4)
Query Neighborhood Hits	76	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FARP1_HUMAN
θ value	1.01059e-59 (rank : 17)	NC score	0.800796 (rank : 22)
Query Neighborhood Hits	76	Target Neighborhood Hits	241	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FARP2_MOUSE
θ value	1.0458e-56 (rank : 18)	NC score	0.768659 (rank : 26)
Query Neighborhood Hits	76	Target Neighborhood Hits	209	Shared Neighborhood Hits	47
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_HUMAN
θ value	5.73848e-55 (rank : 19)	NC score	0.776713 (rank : 25)
Query Neighborhood Hits	76	Target Neighborhood Hits	240	Shared Neighborhood Hits	46
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

PTN3_HUMAN
θ value	5.37103e-53 (rank : 20)	NC score	0.653987 (rank : 36)
Query Neighborhood Hits	76	Target Neighborhood Hits	258	Shared Neighborhood Hits	47
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN21_MOUSE
θ value	4.72714e-33 (rank : 21)	NC score	0.626066 (rank : 38)
Query Neighborhood Hits	76	Target Neighborhood Hits	155	Shared Neighborhood Hits	49
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
θ value	1.0531e-32 (rank : 22)	NC score	0.623892 (rank : 39)
Query Neighborhood Hits	76	Target Neighborhood Hits	143	Shared Neighborhood Hits	48
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN14_MOUSE
θ value	8.91499e-32 (rank : 23)	NC score	0.610954 (rank : 40)
Query Neighborhood Hits	76	Target Neighborhood Hits	142	Shared Neighborhood Hits	48
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

EZRI_HUMAN
θ value	7.54701e-31 (rank : 24)	NC score	0.747064 (rank : 27)
Query Neighborhood Hits	76	Target Neighborhood Hits	663	Shared Neighborhood Hits	57
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

PTN14_HUMAN
θ value	7.54701e-31 (rank : 25)	NC score	0.602676 (rank : 41)
Query Neighborhood Hits	76	Target Neighborhood Hits	163	Shared Neighborhood Hits	48
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

EZRI_MOUSE
θ value	1.6813e-30 (rank : 26)	NC score	0.742444 (rank : 28)
Query Neighborhood Hits	76	Target Neighborhood Hits	693	Shared Neighborhood Hits	56
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

RADI_HUMAN
θ value	2.19584e-30 (rank : 27)	NC score	0.728810 (rank : 29)
Query Neighborhood Hits	76	Target Neighborhood Hits	741	Shared Neighborhood Hits	55
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	2.19584e-30 (rank : 28)	NC score	0.725472 (rank : 30)
Query Neighborhood Hits	76	Target Neighborhood Hits	773	Shared Neighborhood Hits	59
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

MYLIP_MOUSE
θ value	1.4233e-29 (rank : 29)	NC score	0.875980 (rank : 16)
Query Neighborhood Hits	76	Target Neighborhood Hits	139	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_HUMAN
θ value	2.42779e-29 (rank : 30)	NC score	0.859683 (rank : 17)
Query Neighborhood Hits	76	Target Neighborhood Hits	162	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MOES_MOUSE
θ value	7.80994e-28 (rank : 31)	NC score	0.676001 (rank : 33)
Query Neighborhood Hits	76	Target Neighborhood Hits	923	Shared Neighborhood Hits	55
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_HUMAN
θ value	1.02001e-27 (rank : 32)	NC score	0.683610 (rank : 31)
Query Neighborhood Hits	76	Target Neighborhood Hits	892	Shared Neighborhood Hits	55
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MERL_HUMAN
θ value	1.47289e-26 (rank : 33)	NC score	0.781855 (rank : 24)
Query Neighborhood Hits	76	Target Neighborhood Hits	532	Shared Neighborhood Hits	51
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	1.92365e-26 (rank : 34)	NC score	0.782370 (rank : 23)
Query Neighborhood Hits	76	Target Neighborhood Hits	524	Shared Neighborhood Hits	51
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

FRM4A_HUMAN
θ value	1.37858e-24 (rank : 35)	NC score	0.803744 (rank : 21)
Query Neighborhood Hits	76	Target Neighborhood Hits	110	Shared Neighborhood Hits	51
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_MOUSE
θ value	1.80048e-24 (rank : 36)	NC score	0.804621 (rank : 20)
Query Neighborhood Hits	76	Target Neighborhood Hits	108	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4B_HUMAN
θ value	1.29031e-22 (rank : 37)	NC score	0.811056 (rank : 18)
Query Neighborhood Hits	76	Target Neighborhood Hits	117	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
θ value	2.20094e-22 (rank : 38)	NC score	0.809298 (rank : 19)
Query Neighborhood Hits	76	Target Neighborhood Hits	109	Shared Neighborhood Hits	49
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

PTN13_HUMAN
θ value	5.99374e-20 (rank : 39)	NC score	0.473544 (rank : 43)
Query Neighborhood Hits	76	Target Neighborhood Hits	471	Shared Neighborhood Hits	49
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
θ value	1.33526e-19 (rank : 40)	NC score	0.483267 (rank : 42)
Query Neighborhood Hits	76	Target Neighborhood Hits	426	Shared Neighborhood Hits	48
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

TLN2_MOUSE
θ value	1.133e-10 (rank : 41)	NC score	0.442155 (rank : 45)
Query Neighborhood Hits	76	Target Neighborhood Hits	149	Shared Neighborhood Hits	48
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN2_HUMAN
θ value	1.9326e-10 (rank : 42)	NC score	0.437186 (rank : 47)
Query Neighborhood Hits	76	Target Neighborhood Hits	157	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN1_HUMAN
θ value	6.21693e-09 (rank : 43)	NC score	0.443724 (rank : 44)
Query Neighborhood Hits	76	Target Neighborhood Hits	218	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	6.21693e-09 (rank : 44)	NC score	0.440383 (rank : 46)
Query Neighborhood Hits	76	Target Neighborhood Hits	213	Shared Neighborhood Hits	44
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

FRMD6_HUMAN
θ value	1.99992e-07 (rank : 45)	NC score	0.661642 (rank : 35)
Query Neighborhood Hits	76	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

FRMD6_MOUSE
θ value	1.69304e-06 (rank : 46)	NC score	0.667389 (rank : 34)
Query Neighborhood Hits	76	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRMD1_HUMAN
θ value	6.43352e-06 (rank : 47)	NC score	0.640499 (rank : 37)
Query Neighborhood Hits	76	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

TEKT1_MOUSE
θ value	0.125558 (rank : 48)	NC score	0.021222 (rank : 130)
Query Neighborhood Hits	76	Target Neighborhood Hits	399	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DAJ2	Gene names	Tekt1
Domain Architecture
Description	Tektin-1.

ZC313_HUMAN
θ value	1.38821 (rank : 49)	NC score	0.033575 (rank : 125)
Query Neighborhood Hits	76	Target Neighborhood Hits	772	Shared Neighborhood Hits	16
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ABCA6_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.003627 (rank : 152)
Query Neighborhood Hits	76	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K441, Q8BGH0, Q8BPT1	Gene names	Abca6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

A2MG_MOUSE
θ value	2.36792 (rank : 51)	NC score	0.006694 (rank : 146)
Query Neighborhood Hits	76	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q61838, Q60628	Gene names	A2m
Domain Architecture
Description	Alpha-2-macroglobulin precursor (Alpha-2-M) [Contains: Alpha-2- macroglobulin 165 kDa subunit; Alpha-2-macroglobulin 35 kDa subunit].

CENPF_HUMAN
θ value	2.36792 (rank : 52)	NC score	0.021824 (rank : 127)
Query Neighborhood Hits	76	Target Neighborhood Hits	1932	Shared Neighborhood Hits	32
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CNTN4_HUMAN
θ value	2.36792 (rank : 53)	NC score	-0.000363 (rank : 153)
Query Neighborhood Hits	76	Target Neighborhood Hits	449	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

IP3KA_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.011643 (rank : 139)
Query Neighborhood Hits	76	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

LMNB1_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.014790 (rank : 135)
Query Neighborhood Hits	76	Target Neighborhood Hits	714	Shared Neighborhood Hits	14
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

ANK2_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.004780 (rank : 149)
Query Neighborhood Hits	76	Target Neighborhood Hits	1615	Shared Neighborhood Hits	17
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

MYO10_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.028081 (rank : 126)
Query Neighborhood Hits	76	Target Neighborhood Hits	920	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

ROCK2_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.005359 (rank : 148)
Query Neighborhood Hits	76	Target Neighborhood Hits	2073	Shared Neighborhood Hits	24
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ROCK2_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.004663 (rank : 150)
Query Neighborhood Hits	76	Target Neighborhood Hits	2072	Shared Neighborhood Hits	23
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

VATC_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.014726 (rank : 136)
Query Neighborhood Hits	76	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P21283	Gene names	ATP6V1C1, ATP6C, ATP6D, VATC
Domain Architecture
Description	Vacuolar ATP synthase subunit C (EC 3.6.3.14) (V-ATPase C subunit) (Vacuolar proton pump C subunit).

BRD8_MOUSE
θ value	5.27518 (rank : 61)	NC score	0.008438 (rank : 142)
Query Neighborhood Hits	76	Target Neighborhood Hits	422	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

GIT1_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.015117 (rank : 134)
Query Neighborhood Hits	76	Target Neighborhood Hits	341	Shared Neighborhood Hits	7
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

LMNB1_MOUSE
θ value	5.27518 (rank : 63)	NC score	0.015376 (rank : 133)
Query Neighborhood Hits	76	Target Neighborhood Hits	719	Shared Neighborhood Hits	14
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

MYT1L_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.008178 (rank : 143)
Query Neighborhood Hits	76	Target Neighborhood Hits	471	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

AP1G2_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.003936 (rank : 151)
Query Neighborhood Hits	76	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	O75843, O75504	Gene names	AP1G2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

BRD8_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.006788 (rank : 145)
Query Neighborhood Hits	76	Target Neighborhood Hits	292	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

GIT1_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.010639 (rank : 140)
Query Neighborhood Hits	76	Target Neighborhood Hits	336	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GP156_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.006417 (rank : 147)
Query Neighborhood Hits	76	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

HC127_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.021774 (rank : 128)
Query Neighborhood Hits	76	Target Neighborhood Hits	292	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NQZ6, Q5JTF9, Q9H9C3, Q9H9H7, Q9ULQ4	Gene names	HCA127, KIAA1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127.

HC127_MOUSE
θ value	6.88961 (rank : 70)	NC score	0.021774 (rank : 129)
Query Neighborhood Hits	76	Target Neighborhood Hits	292	Shared Neighborhood Hits	10
SwissProt Accessions	Q68FG0, Q6ZPW6	Gene names	Hca127, Kiaa1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127 homolog.

TP53B_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.018215 (rank : 131)
Query Neighborhood Hits	76	Target Neighborhood Hits	413	Shared Neighborhood Hits	10
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

VATC_MOUSE
θ value	6.88961 (rank : 72)	NC score	0.012998 (rank : 138)
Query Neighborhood Hits	76	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1G3	Gene names	Atp6v1c1, Atp6c, Vatc
Domain Architecture
Description	Vacuolar ATP synthase subunit C (EC 3.6.3.14) (V-ATPase C subunit) (Vacuolar proton pump C subunit).

AL2SA_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.016165 (rank : 132)
Query Neighborhood Hits	76	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q53TS8, Q8NCN6, Q96LN4	Gene names	ALS2CR11
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein.

FLT3L_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.007966 (rank : 144)
Query Neighborhood Hits	76	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P49771	Gene names	FLT3LG
Domain Architecture
Description	SL cytokine precursor (Fms-related tyrosine kinase 3 ligand) (Flt3 ligand) (Flt3L).

IP3KA_MOUSE
θ value	8.99809 (rank : 75)	NC score	0.008831 (rank : 141)
Query Neighborhood Hits	76	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R071	Gene names	Itpka
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

NBN_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.013051 (rank : 137)
Query Neighborhood Hits	76	Target Neighborhood Hits	226	Shared Neighborhood Hits	6
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

ARHG4_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.050840 (rank : 123)
Query Neighborhood Hits	76	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.052014 (rank : 120)
Query Neighborhood Hits	76	Target Neighborhood Hits	185	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

CA106_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.099160 (rank : 83)
Query Neighborhood Hits	76	Target Neighborhood Hits	124	Shared Neighborhood Hits	4
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.097785 (rank : 84)
Query Neighborhood Hits	76	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

CD45_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.100884 (rank : 82)
Query Neighborhood Hits	76	Target Neighborhood Hits	243	Shared Neighborhood Hits	10
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD45_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.105379 (rank : 71)
Query Neighborhood Hits	76	Target Neighborhood Hits	178	Shared Neighborhood Hits	12
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

FGD1_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.059373 (rank : 113)
Query Neighborhood Hits	76	Target Neighborhood Hits	367	Shared Neighborhood Hits	5
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.057095 (rank : 116)
Query Neighborhood Hits	76	Target Neighborhood Hits	387	Shared Neighborhood Hits	4
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.050658 (rank : 124)
Query Neighborhood Hits	76	Target Neighborhood Hits	151	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.055040 (rank : 117)
Query Neighborhood Hits	76	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.053542 (rank : 118)
Query Neighborhood Hits	76	Target Neighborhood Hits	249	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD3_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.051836 (rank : 121)
Query Neighborhood Hits	76	Target Neighborhood Hits	257	Shared Neighborhood Hits	3
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD4_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.060612 (rank : 111)
Query Neighborhood Hits	76	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.061043 (rank : 110)
Query Neighborhood Hits	76	Target Neighborhood Hits	227	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD5_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.064401 (rank : 105)
Query Neighborhood Hits	76	Target Neighborhood Hits	235	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD5_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.060554 (rank : 112)
Query Neighborhood Hits	76	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD6_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.062756 (rank : 107)
Query Neighborhood Hits	76	Target Neighborhood Hits	237	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.062104 (rank : 108)
Query Neighborhood Hits	76	Target Neighborhood Hits	282	Shared Neighborhood Hits	5
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

HIP1R_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.058610 (rank : 114)
Query Neighborhood Hits	76	Target Neighborhood Hits	809	Shared Neighborhood Hits	24
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1R_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.053376 (rank : 119)
Query Neighborhood Hits	76	Target Neighborhood Hits	959	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

HIP1_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.058351 (rank : 115)
Query Neighborhood Hits	76	Target Neighborhood Hits	1016	Shared Neighborhood Hits	26
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

KRIT1_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.088813 (rank : 89)
Query Neighborhood Hits	76	Target Neighborhood Hits	258	Shared Neighborhood Hits	20
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

KRIT1_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.081972 (rank : 100)
Query Neighborhood Hits	76	Target Neighborhood Hits	258	Shared Neighborhood Hits	22
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

MESD1_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.061203 (rank : 109)
Query Neighborhood Hits	76	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1K6	Gene names	MESDC1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

MESD1_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.062927 (rank : 106)
Query Neighborhood Hits	76	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERE8, Q542D0	Gene names	Mesdc1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

PKHA6_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.051661 (rank : 122)
Query Neighborhood Hits	76	Target Neighborhood Hits	591	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PTN11_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.104445 (rank : 76)
Query Neighborhood Hits	76	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.104453 (rank : 74)
Query Neighborhood Hits	76	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN12_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.111184 (rank : 59)
Query Neighborhood Hits	76	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.110930 (rank : 63)
Query Neighborhood Hits	76	Target Neighborhood Hits	123	Shared Neighborhood Hits	10
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN18_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.120317 (rank : 50)
Query Neighborhood Hits	76	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.116623 (rank : 53)
Query Neighborhood Hits	76	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN1_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.120255 (rank : 51)
Query Neighborhood Hits	76	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.120629 (rank : 49)
Query Neighborhood Hits	76	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN22_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.113017 (rank : 56)
Query Neighborhood Hits	76	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN22_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.111179 (rank : 60)
Query Neighborhood Hits	76	Target Neighborhood Hits	179	Shared Neighborhood Hits	8
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN23_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.103672 (rank : 78)
Query Neighborhood Hits	76	Target Neighborhood Hits	646	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.102077 (rank : 81)
Query Neighborhood Hits	76	Target Neighborhood Hits	726	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN2_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.120207 (rank : 52)
Query Neighborhood Hits	76	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN2_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.121464 (rank : 48)
Query Neighborhood Hits	76	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN5_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.104450 (rank : 75)
Query Neighborhood Hits	76	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.104487 (rank : 73)
Query Neighborhood Hits	76	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN6_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.111159 (rank : 61)
Query Neighborhood Hits	76	Target Neighborhood Hits	234	Shared Neighborhood Hits	8
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.111130 (rank : 62)
Query Neighborhood Hits	76	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN7_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.111279 (rank : 58)
Query Neighborhood Hits	76	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.112490 (rank : 57)
Query Neighborhood Hits	76	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN9_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.116395 (rank : 54)
Query Neighborhood Hits	76	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.116031 (rank : 55)
Query Neighborhood Hits	76	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPR2_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.108533 (rank : 65)
Query Neighborhood Hits	76	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.108403 (rank : 66)
Query Neighborhood Hits	76	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRA_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.097115 (rank : 87)
Query Neighborhood Hits	76	Target Neighborhood Hits	101	Shared Neighborhood Hits	9
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.097134 (rank : 86)
Query Neighborhood Hits	76	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRB_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.102098 (rank : 80)
Query Neighborhood Hits	76	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRD_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.068283 (rank : 102)
Query Neighborhood Hits	76	Target Neighborhood Hits	485	Shared Neighborhood Hits	10
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.065775 (rank : 104)
Query Neighborhood Hits	76	Target Neighborhood Hits	491	Shared Neighborhood Hits	10
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRE_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.097427 (rank : 85)
Query Neighborhood Hits	76	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.096883 (rank : 88)
Query Neighborhood Hits	76	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRF_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.066618 (rank : 103)
Query Neighborhood Hits	76	Target Neighborhood Hits	489	Shared Neighborhood Hits	9
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRG_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.086409 (rank : 94)
Query Neighborhood Hits	76	Target Neighborhood Hits	231	Shared Neighborhood Hits	8
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.086681 (rank : 93)
Query Neighborhood Hits	76	Target Neighborhood Hits	260	Shared Neighborhood Hits	9
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRJ_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.104150 (rank : 77)
Query Neighborhood Hits	76	Target Neighborhood Hits	207	Shared Neighborhood Hits	8
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRJ_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.104641 (rank : 72)
Query Neighborhood Hits	76	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRK_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.087510 (rank : 91)
Query Neighborhood Hits	76	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.088358 (rank : 90)
Query Neighborhood Hits	76	Target Neighborhood Hits	223	Shared Neighborhood Hits	9
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRM_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.082464 (rank : 99)
Query Neighborhood Hits	76	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.082867 (rank : 97)
Query Neighborhood Hits	76	Target Neighborhood Hits	238	Shared Neighborhood Hits	9
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRN_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.108358 (rank : 67)
Query Neighborhood Hits	76	Target Neighborhood Hits	156	Shared Neighborhood Hits	10
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.107997 (rank : 68)
Query Neighborhood Hits	76	Target Neighborhood Hits	240	Shared Neighborhood Hits	8
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRO_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.108846 (rank : 64)
Query Neighborhood Hits	76	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRR_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.106334 (rank : 70)
Query Neighborhood Hits	76	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.106753 (rank : 69)
Query Neighborhood Hits	76	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRS_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.069624 (rank : 101)
Query Neighborhood Hits	76	Target Neighborhood Hits	472	Shared Neighborhood Hits	9
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRT_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.084783 (rank : 95)
Query Neighborhood Hits	76	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.084742 (rank : 96)
Query Neighborhood Hits	76	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRU_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.082558 (rank : 98)
Query Neighborhood Hits	76	Target Neighborhood Hits	237	Shared Neighborhood Hits	9
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRV_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.103633 (rank : 79)
Query Neighborhood Hits	76	Target Neighborhood Hits	179	Shared Neighborhood Hits	8
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRZ_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.087111 (rank : 92)
Query Neighborhood Hits	76	Target Neighborhood Hits	255	Shared Neighborhood Hits	9
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

Hits sorted by NC score

E41L5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	76	Target Neighborhood Hits	76	Shared Neighborhood Hits	76
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LB_MOUSE
NC score	0.993443 (rank : 2)	θ value	2.33935e-157 (rank : 3)
Query Neighborhood Hits	76	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

E41LB_HUMAN
NC score	0.990791 (rank : 3)	θ value	3.1544e-162 (rank : 2)
Query Neighborhood Hits	76	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

FRMD5_MOUSE
NC score	0.972856 (rank : 4)	θ value	5.91091e-68 (rank : 16)
Query Neighborhood Hits	76	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41LA_MOUSE
NC score	0.972318 (rank : 5)	θ value	2.73936e-73 (rank : 12)
Query Neighborhood Hits	76	Target Neighborhood Hits	85	Shared Neighborhood Hits	48
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_HUMAN
NC score	0.972152 (rank : 6)	θ value	5.33382e-77 (rank : 5)
Query Neighborhood Hits	76	Target Neighborhood Hits	87	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

FRMD5_HUMAN
NC score	0.970820 (rank : 7)	θ value	4.52582e-68 (rank : 15)
Query Neighborhood Hits	76	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41L3_HUMAN
NC score	0.965636 (rank : 8)	θ value	8.51556e-75 (rank : 10)
Query Neighborhood Hits	76	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41L1_MOUSE
NC score	0.963039 (rank : 9)	θ value	8.51556e-75 (rank : 9)
Query Neighborhood Hits	76	Target Neighborhood Hits	106	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

41_HUMAN
NC score	0.959913 (rank : 10)	θ value	1.60597e-73 (rank : 11)
Query Neighborhood Hits	76	Target Neighborhood Hits	157	Shared Neighborhood Hits	49
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

E41L1_HUMAN
NC score	0.958107 (rank : 11)	θ value	7.70199e-76 (rank : 7)
Query Neighborhood Hits	76	Target Neighborhood Hits	180	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

41_MOUSE
NC score	0.957170 (rank : 12)	θ value	1.96316e-71 (rank : 14)
Query Neighborhood Hits	76	Target Neighborhood Hits	184	Shared Neighborhood Hits	49
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

E41L3_MOUSE
NC score	0.952271 (rank : 13)	θ value	3.45727e-76 (rank : 6)
Query Neighborhood Hits	76	Target Neighborhood Hits	250	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L2_HUMAN
NC score	0.948939 (rank : 14)	θ value	7.44272e-79 (rank : 4)
Query Neighborhood Hits	76	Target Neighborhood Hits	287	Shared Neighborhood Hits	48
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L2_MOUSE
NC score	0.926453 (rank : 15)	θ value	7.70199e-76 (rank : 8)
Query Neighborhood Hits	76	Target Neighborhood Hits	459	Shared Neighborhood Hits	49
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MYLIP_MOUSE
NC score	0.875980 (rank : 16)	θ value	1.4233e-29 (rank : 29)
Query Neighborhood Hits	76	Target Neighborhood Hits	139	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_HUMAN
NC score	0.859683 (rank : 17)	θ value	2.42779e-29 (rank : 30)
Query Neighborhood Hits	76	Target Neighborhood Hits	162	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

FRM4B_HUMAN
NC score	0.811056 (rank : 18)	θ value	1.29031e-22 (rank : 37)
Query Neighborhood Hits	76	Target Neighborhood Hits	117	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
NC score	0.809298 (rank : 19)	θ value	2.20094e-22 (rank : 38)
Query Neighborhood Hits	76	Target Neighborhood Hits	109	Shared Neighborhood Hits	49
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4A_MOUSE
NC score	0.804621 (rank : 20)	θ value	1.80048e-24 (rank : 36)
Query Neighborhood Hits	76	Target Neighborhood Hits	108	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_HUMAN
NC score	0.803744 (rank : 21)	θ value	1.37858e-24 (rank : 35)
Query Neighborhood Hits	76	Target Neighborhood Hits	110	Shared Neighborhood Hits	51
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FARP1_HUMAN
NC score	0.800796 (rank : 22)	θ value	1.01059e-59 (rank : 17)
Query Neighborhood Hits	76	Target Neighborhood Hits	241	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

MERL_MOUSE
NC score	0.782370 (rank : 23)	θ value	1.92365e-26 (rank : 34)
Query Neighborhood Hits	76	Target Neighborhood Hits	524	Shared Neighborhood Hits	51
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MERL_HUMAN
NC score	0.781855 (rank : 24)	θ value	1.47289e-26 (rank : 33)
Query Neighborhood Hits	76	Target Neighborhood Hits	532	Shared Neighborhood Hits	51
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

FARP2_HUMAN
NC score	0.776713 (rank : 25)	θ value	5.73848e-55 (rank : 19)
Query Neighborhood Hits	76	Target Neighborhood Hits	240	Shared Neighborhood Hits	46
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
NC score	0.768659 (rank : 26)	θ value	1.0458e-56 (rank : 18)
Query Neighborhood Hits	76	Target Neighborhood Hits	209	Shared Neighborhood Hits	47
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

EZRI_HUMAN
NC score	0.747064 (rank : 27)	θ value	7.54701e-31 (rank : 24)
Query Neighborhood Hits	76	Target Neighborhood Hits	663	Shared Neighborhood Hits	57
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
NC score	0.742444 (rank : 28)	θ value	1.6813e-30 (rank : 26)
Query Neighborhood Hits	76	Target Neighborhood Hits	693	Shared Neighborhood Hits	56
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

RADI_HUMAN
NC score	0.728810 (rank : 29)	θ value	2.19584e-30 (rank : 27)
Query Neighborhood Hits	76	Target Neighborhood Hits	741	Shared Neighborhood Hits	55
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
NC score	0.725472 (rank : 30)	θ value	2.19584e-30 (rank : 28)
Query Neighborhood Hits	76	Target Neighborhood Hits	773	Shared Neighborhood Hits	59
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

MOES_HUMAN
NC score	0.683610 (rank : 31)	θ value	1.02001e-27 (rank : 32)
Query Neighborhood Hits	76	Target Neighborhood Hits	892	Shared Neighborhood Hits	55
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

PTN4_HUMAN
NC score	0.681309 (rank : 32)	θ value	6.7473e-72 (rank : 13)
Query Neighborhood Hits	76	Target Neighborhood Hits	303	Shared Neighborhood Hits	47
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

MOES_MOUSE
NC score	0.676001 (rank : 33)	θ value	7.80994e-28 (rank : 31)
Query Neighborhood Hits	76	Target Neighborhood Hits	923	Shared Neighborhood Hits	55
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

FRMD6_MOUSE
NC score	0.667389 (rank : 34)	θ value	1.69304e-06 (rank : 46)
Query Neighborhood Hits	76	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRMD6_HUMAN
NC score	0.661642 (rank : 35)	θ value	1.99992e-07 (rank : 45)
Query Neighborhood Hits	76	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

PTN3_HUMAN
NC score	0.653987 (rank : 36)	θ value	5.37103e-53 (rank : 20)
Query Neighborhood Hits	76	Target Neighborhood Hits	258	Shared Neighborhood Hits	47
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

FRMD1_HUMAN
NC score	0.640499 (rank : 37)	θ value	6.43352e-06 (rank : 47)
Query Neighborhood Hits	76	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

PTN21_MOUSE
NC score	0.626066 (rank : 38)	θ value	4.72714e-33 (rank : 21)
Query Neighborhood Hits	76	Target Neighborhood Hits	155	Shared Neighborhood Hits	49
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
NC score	0.623892 (rank : 39)	θ value	1.0531e-32 (rank : 22)
Query Neighborhood Hits	76	Target Neighborhood Hits	143	Shared Neighborhood Hits	48
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN14_MOUSE
NC score	0.610954 (rank : 40)	θ value	8.91499e-32 (rank : 23)
Query Neighborhood Hits	76	Target Neighborhood Hits	142	Shared Neighborhood Hits	48
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN14_HUMAN
NC score	0.602676 (rank : 41)	θ value	7.54701e-31 (rank : 25)
Query Neighborhood Hits	76	Target Neighborhood Hits	163	Shared Neighborhood Hits	48
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN13_MOUSE
NC score	0.483267 (rank : 42)	θ value	1.33526e-19 (rank : 40)
Query Neighborhood Hits	76	Target Neighborhood Hits	426	Shared Neighborhood Hits	48
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN13_HUMAN
NC score	0.473544 (rank : 43)	θ value	5.99374e-20 (rank : 39)
Query Neighborhood Hits	76	Target Neighborhood Hits	471	Shared Neighborhood Hits	49
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

TLN1_HUMAN
NC score	0.443724 (rank : 44)	θ value	6.21693e-09 (rank : 43)
Query Neighborhood Hits	76	Target Neighborhood Hits	218	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN2_MOUSE
NC score	0.442155 (rank : 45)	θ value	1.133e-10 (rank : 41)
Query Neighborhood Hits	76	Target Neighborhood Hits	149	Shared Neighborhood Hits	48
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN1_MOUSE
NC score	0.440383 (rank : 46)	θ value	6.21693e-09 (rank : 44)
Query Neighborhood Hits	76	Target Neighborhood Hits	213	Shared Neighborhood Hits	44
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN2_HUMAN
NC score	0.437186 (rank : 47)	θ value	1.9326e-10 (rank : 42)
Query Neighborhood Hits	76	Target Neighborhood Hits	157	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

PTN2_MOUSE
NC score	0.121464 (rank : 48)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	76	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN1_MOUSE
NC score	0.120629 (rank : 49)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	76	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN18_HUMAN
NC score	0.120317 (rank : 50)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	76	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN1_HUMAN
NC score	0.120255 (rank : 51)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	76	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN2_HUMAN
NC score	0.120207 (rank : 52)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	76	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN18_MOUSE
NC score	0.116623 (rank : 53)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	76	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN9_HUMAN
NC score	0.116395 (rank : 54)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	76	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
NC score	0.116031 (rank : 55)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	76	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN22_HUMAN
NC score	0.113017 (rank : 56)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	76	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN7_MOUSE
NC score	0.112490 (rank : 57)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	76	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN7_HUMAN
NC score	0.111279 (rank : 58)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	76	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN12_HUMAN
NC score	0.111184 (rank : 59)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	76	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN22_MOUSE
NC score	0.111179 (rank : 60)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	76	Target Neighborhood Hits	179	Shared Neighborhood Hits	8
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN6_HUMAN
NC score	0.111159 (rank : 61)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	76	Target Neighborhood Hits	234	Shared Neighborhood Hits	8
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
NC score	0.111130 (rank : 62)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	76	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN12_MOUSE
NC score	0.110930 (rank : 63)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	76	Target Neighborhood Hits	123	Shared Neighborhood Hits	10
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTPRO_HUMAN
NC score	0.108846 (rank : 64)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	76	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPR2_HUMAN
NC score	0.108533 (rank : 65)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	76	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
NC score	0.108403 (rank : 66)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	76	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRN_HUMAN
NC score	0.108358 (rank : 67)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	76	Target Neighborhood Hits	156	Shared Neighborhood Hits	10
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
NC score	0.107997 (rank : 68)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	76	Target Neighborhood Hits	240	Shared Neighborhood Hits	8
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRR_MOUSE
NC score	0.106753 (rank : 69)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	76	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRR_HUMAN
NC score	0.106334 (rank : 70)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	76	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

CD45_MOUSE
NC score	0.105379 (rank : 71)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	76	Target Neighborhood Hits	178	Shared Neighborhood Hits	12
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTPRJ_MOUSE
NC score	0.104641 (rank : 72)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	76	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTN5_MOUSE
NC score	0.104487 (rank : 73)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	76	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN11_MOUSE
NC score	0.104453 (rank : 74)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	76	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN5_HUMAN
NC score	0.104450 (rank : 75)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	76	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN11_HUMAN
NC score	0.104445 (rank : 76)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	76	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTPRJ_HUMAN
NC score	0.104150 (rank : 77)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	76	Target Neighborhood Hits	207	Shared Neighborhood Hits	8
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTN23_HUMAN
NC score	0.103672 (rank : 78)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	76	Target Neighborhood Hits	646	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTPRV_MOUSE
NC score	0.103633 (rank : 79)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	76	Target Neighborhood Hits	179	Shared Neighborhood Hits	8
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRB_HUMAN
NC score	0.102098 (rank : 80)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	76	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTN23_MOUSE
NC score	0.102077 (rank : 81)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	76	Target Neighborhood Hits	726	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

CD45_HUMAN
NC score	0.100884 (rank : 82)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	76	Target Neighborhood Hits	243	Shared Neighborhood Hits	10
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CA106_HUMAN
NC score	0.099160 (rank : 83)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	76	Target Neighborhood Hits	124	Shared Neighborhood Hits	4
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
NC score	0.097785 (rank : 84)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	76	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

PTPRE_HUMAN
NC score	0.097427 (rank : 85)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	76	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_MOUSE
NC score	0.097134 (rank : 86)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	76	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRA_HUMAN
NC score	0.097115 (rank : 87)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	76	Target Neighborhood Hits	101	Shared Neighborhood Hits	9
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRE_MOUSE
NC score	0.096883 (rank : 88)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	76	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

KRIT1_HUMAN
NC score	0.088813 (rank : 89)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	76	Target Neighborhood Hits	258	Shared Neighborhood Hits	20
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

PTPRK_MOUSE
NC score	0.088358 (rank : 90)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	76	Target Neighborhood Hits	223	Shared Neighborhood Hits	9
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_HUMAN
NC score	0.087510 (rank : 91)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	76	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRZ_HUMAN
NC score	0.087111 (rank : 92)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	76	Target Neighborhood Hits	255	Shared Neighborhood Hits	9
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTPRG_MOUSE
NC score	0.086681 (rank : 93)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	76	Target Neighborhood Hits	260	Shared Neighborhood Hits	9
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_HUMAN
NC score	0.086409 (rank : 94)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	76	Target Neighborhood Hits	231	Shared Neighborhood Hits	8
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRT_HUMAN
NC score	0.084783 (rank : 95)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	76	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
NC score	0.084742 (rank : 96)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	76	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRM_MOUSE
NC score	0.082867 (rank : 97)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	76	Target Neighborhood Hits	238	Shared Neighborhood Hits	9
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRU_HUMAN
NC score	0.082558 (rank : 98)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	76	Target Neighborhood Hits	237	Shared Neighborhood Hits	9
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRM_HUMAN
NC score	0.082464 (rank : 99)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	76	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

KRIT1_MOUSE
NC score	0.081972 (rank : 100)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	76	Target Neighborhood Hits	258	Shared Neighborhood Hits	22
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

PTPRS_HUMAN
NC score	0.069624 (rank : 101)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	76	Target Neighborhood Hits	472	Shared Neighborhood Hits	9
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRD_HUMAN
NC score	0.068283 (rank : 102)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	76	Target Neighborhood Hits	485	Shared Neighborhood Hits	10
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRF_HUMAN
NC score	0.066618 (rank : 103)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	76	Target Neighborhood Hits	489	Shared Neighborhood Hits	9
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRD_MOUSE
NC score	0.065775 (rank : 104)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	76	Target Neighborhood Hits	491	Shared Neighborhood Hits	10
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

FGD5_HUMAN
NC score	0.064401 (rank : 105)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	76	Target Neighborhood Hits	235	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

MESD1_MOUSE
NC score	0.062927 (rank : 106)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	76	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERE8, Q542D0	Gene names	Mesdc1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

FGD6_HUMAN
NC score	0.062756 (rank : 107)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	76	Target Neighborhood Hits	237	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
NC score	0.062104 (rank : 108)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	76	Target Neighborhood Hits	282	Shared Neighborhood Hits	5
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

MESD1_HUMAN
NC score	0.061203 (rank : 109)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	76	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1K6	Gene names	MESDC1
Domain Architecture	No domain graphic available
Description	Mesoderm development candidate 1.

FGD4_MOUSE
NC score	0.061043 (rank : 110)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	76	Target Neighborhood Hits	227	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD4_HUMAN
NC score	0.060612 (rank : 111)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	76	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD5_MOUSE
NC score	0.060554 (rank : 112)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	76	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD1_HUMAN
NC score	0.059373 (rank : 113)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	76	Target Neighborhood Hits	367	Shared Neighborhood Hits	5
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

HIP1R_HUMAN
NC score	0.058610 (rank : 114)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	76	Target Neighborhood Hits	809	Shared Neighborhood Hits	24
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1_HUMAN
NC score	0.058351 (rank : 115)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	76	Target Neighborhood Hits	1016	Shared Neighborhood Hits	26
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

FGD1_MOUSE
NC score	0.057095 (rank : 116)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	76	Target Neighborhood Hits	387	Shared Neighborhood Hits	4
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_MOUSE
NC score	0.055040 (rank : 117)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	76	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_HUMAN
NC score	0.053542 (rank : 118)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	76	Target Neighborhood Hits	249	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

HIP1R_MOUSE
NC score	0.053376 (rank : 119)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	76	Target Neighborhood Hits	959	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

ARHG4_MOUSE
NC score	0.052014 (rank : 120)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	76	Target Neighborhood Hits	185	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

FGD3_MOUSE
NC score	0.051836 (rank : 121)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	76	Target Neighborhood Hits	257	Shared Neighborhood Hits	3
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

PKHA6_MOUSE
NC score	0.051661 (rank : 122)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	76	Target Neighborhood Hits	591	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

ARHG4_HUMAN
NC score	0.050840 (rank : 123)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	76	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

FGD2_HUMAN
NC score	0.050658 (rank : 124)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	76	Target Neighborhood Hits	151	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

ZC313_HUMAN
NC score	0.033575 (rank : 125)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	76	Target Neighborhood Hits	772	Shared Neighborhood Hits	16
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

MYO10_HUMAN
NC score	0.028081 (rank : 126)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	76	Target Neighborhood Hits	920	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

CENPF_HUMAN
NC score	0.021824 (rank : 127)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	76	Target Neighborhood Hits	1932	Shared Neighborhood Hits	32
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

HC127_HUMAN
NC score	0.021774 (rank : 128)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	76	Target Neighborhood Hits	292	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NQZ6, Q5JTF9, Q9H9C3, Q9H9H7, Q9ULQ4	Gene names	HCA127, KIAA1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127.

HC127_MOUSE
NC score	0.021774 (rank : 129)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	76	Target Neighborhood Hits	292	Shared Neighborhood Hits	10
SwissProt Accessions	Q68FG0, Q6ZPW6	Gene names	Hca127, Kiaa1166
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma-associated antigen 127 homolog.

TEKT1_MOUSE
NC score	0.021222 (rank : 130)	θ value	0.125558 (rank : 48)
Query Neighborhood Hits	76	Target Neighborhood Hits	399	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DAJ2	Gene names	Tekt1
Domain Architecture
Description	Tektin-1.

TP53B_HUMAN
NC score	0.018215 (rank : 131)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	76	Target Neighborhood Hits	413	Shared Neighborhood Hits	10
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

AL2SA_HUMAN
NC score	0.016165 (rank : 132)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	76	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	Q53TS8, Q8NCN6, Q96LN4	Gene names	ALS2CR11
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein.

LMNB1_MOUSE
NC score	0.015376 (rank : 133)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	76	Target Neighborhood Hits	719	Shared Neighborhood Hits	14
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

GIT1_MOUSE
NC score	0.015117 (rank : 134)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	76	Target Neighborhood Hits	341	Shared Neighborhood Hits	7
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

LMNB1_HUMAN
NC score	0.014790 (rank : 135)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	76	Target Neighborhood Hits	714	Shared Neighborhood Hits	14
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

VATC_HUMAN
NC score	0.014726 (rank : 136)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	76	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P21283	Gene names	ATP6V1C1, ATP6C, ATP6D, VATC
Domain Architecture
Description	Vacuolar ATP synthase subunit C (EC 3.6.3.14) (V-ATPase C subunit) (Vacuolar proton pump C subunit).

NBN_HUMAN
NC score	0.013051 (rank : 137)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	76	Target Neighborhood Hits	226	Shared Neighborhood Hits	6
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

VATC_MOUSE
NC score	0.012998 (rank : 138)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	76	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1G3	Gene names	Atp6v1c1, Atp6c, Vatc
Domain Architecture
Description	Vacuolar ATP synthase subunit C (EC 3.6.3.14) (V-ATPase C subunit) (Vacuolar proton pump C subunit).

IP3KA_HUMAN
NC score	0.011643 (rank : 139)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	76	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

GIT1_HUMAN
NC score	0.010639 (rank : 140)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	76	Target Neighborhood Hits	336	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

IP3KA_MOUSE
NC score	0.008831 (rank : 141)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	76	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R071	Gene names	Itpka
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

BRD8_MOUSE
NC score	0.008438 (rank : 142)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	76	Target Neighborhood Hits	422	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

MYT1L_HUMAN
NC score	0.008178 (rank : 143)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	76	Target Neighborhood Hits	471	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

FLT3L_HUMAN
NC score	0.007966 (rank : 144)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	76	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P49771	Gene names	FLT3LG
Domain Architecture
Description	SL cytokine precursor (Fms-related tyrosine kinase 3 ligand) (Flt3 ligand) (Flt3L).

BRD8_HUMAN
NC score	0.006788 (rank : 145)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	76	Target Neighborhood Hits	292	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

A2MG_MOUSE
NC score	0.006694 (rank : 146)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	76	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q61838, Q60628	Gene names	A2m
Domain Architecture
Description	Alpha-2-macroglobulin precursor (Alpha-2-M) [Contains: Alpha-2- macroglobulin 165 kDa subunit; Alpha-2-macroglobulin 35 kDa subunit].

GP156_MOUSE
NC score	0.006417 (rank : 147)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	76	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

ROCK2_HUMAN
NC score	0.005359 (rank : 148)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	76	Target Neighborhood Hits	2073	Shared Neighborhood Hits	24
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ANK2_HUMAN
NC score	0.004780 (rank : 149)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	76	Target Neighborhood Hits	1615	Shared Neighborhood Hits	17
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ROCK2_MOUSE
NC score	0.004663 (rank : 150)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	76	Target Neighborhood Hits	2072	Shared Neighborhood Hits	23
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

AP1G2_HUMAN
NC score	0.003936 (rank : 151)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	76	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	O75843, O75504	Gene names	AP1G2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

ABCA6_MOUSE
NC score	0.003627 (rank : 152)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	76	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K441, Q8BGH0, Q8BPT1	Gene names	Abca6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

CNTN4_HUMAN
NC score	-0.000363 (rank : 153)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	76	Target Neighborhood Hits	449	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).