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Network neighborhood for query Sequence : E41L3_HUMAN

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E41L3_HUMAN
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

E41L3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41L3_MOUSE
θ value	0 (rank : 2)	NC score	0.980983 (rank : 4)
Query Neighborhood Hits	113	Target Neighborhood Hits	250	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L1_HUMAN
θ value	1.72287e-176 (rank : 3)	NC score	0.980953 (rank : 5)
Query Neighborhood Hits	113	Target Neighborhood Hits	180	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_MOUSE
θ value	5.01279e-176 (rank : 4)	NC score	0.986219 (rank : 2)
Query Neighborhood Hits	113	Target Neighborhood Hits	106	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L2_HUMAN
θ value	3.72618e-163 (rank : 5)	NC score	0.973318 (rank : 7)
Query Neighborhood Hits	113	Target Neighborhood Hits	287	Shared Neighborhood Hits	61
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L2_MOUSE
θ value	9.49765e-159 (rank : 6)	NC score	0.952375 (rank : 15)
Query Neighborhood Hits	113	Target Neighborhood Hits	459	Shared Neighborhood Hits	61
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

41_HUMAN
θ value	1.20145e-153 (rank : 7)	NC score	0.981257 (rank : 3)
Query Neighborhood Hits	113	Target Neighborhood Hits	157	Shared Neighborhood Hits	49
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

41_MOUSE
θ value	4.88915e-147 (rank : 8)	NC score	0.979422 (rank : 6)
Query Neighborhood Hits	113	Target Neighborhood Hits	184	Shared Neighborhood Hits	52
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

PTN4_HUMAN
θ value	7.68416e-84 (rank : 9)	NC score	0.678999 (rank : 32)
Query Neighborhood Hits	113	Target Neighborhood Hits	303	Shared Neighborhood Hits	49
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

E41L5_HUMAN
θ value	8.51556e-75 (rank : 10)	NC score	0.965636 (rank : 8)
Query Neighborhood Hits	113	Target Neighborhood Hits	76	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LB_MOUSE
θ value	1.35953e-72 (rank : 11)	NC score	0.965511 (rank : 9)
Query Neighborhood Hits	113	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

E41LB_HUMAN
θ value	6.7473e-72 (rank : 12)	NC score	0.959377 (rank : 12)
Query Neighborhood Hits	113	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

FARP1_HUMAN
θ value	1.27248e-70 (rank : 13)	NC score	0.802663 (rank : 18)
Query Neighborhood Hits	113	Target Neighborhood Hits	241	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

E41LA_HUMAN
θ value	3.70236e-70 (rank : 14)	NC score	0.958406 (rank : 13)
Query Neighborhood Hits	113	Target Neighborhood Hits	87	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

FARP2_MOUSE
θ value	2.3998e-69 (rank : 15)	NC score	0.770864 (rank : 26)
Query Neighborhood Hits	113	Target Neighborhood Hits	209	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_HUMAN
θ value	1.31681e-67 (rank : 16)	NC score	0.778548 (rank : 22)
Query Neighborhood Hits	113	Target Neighborhood Hits	240	Shared Neighborhood Hits	48
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

E41LA_MOUSE
θ value	1.11475e-66 (rank : 17)	NC score	0.958094 (rank : 14)
Query Neighborhood Hits	113	Target Neighborhood Hits	85	Shared Neighborhood Hits	48
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

FRMD5_MOUSE
θ value	1.11475e-66 (rank : 18)	NC score	0.963951 (rank : 10)
Query Neighborhood Hits	113	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_HUMAN
θ value	1.2325e-65 (rank : 19)	NC score	0.961235 (rank : 11)
Query Neighborhood Hits	113	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

PTN3_HUMAN
θ value	4.24587e-58 (rank : 20)	NC score	0.649843 (rank : 36)
Query Neighborhood Hits	113	Target Neighborhood Hits	258	Shared Neighborhood Hits	47
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN21_MOUSE
θ value	1.79215e-40 (rank : 21)	NC score	0.621864 (rank : 38)
Query Neighborhood Hits	113	Target Neighborhood Hits	155	Shared Neighborhood Hits	48
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
θ value	2.34062e-40 (rank : 22)	NC score	0.620046 (rank : 39)
Query Neighborhood Hits	113	Target Neighborhood Hits	143	Shared Neighborhood Hits	47
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

EZRI_MOUSE
θ value	1.46948e-34 (rank : 23)	NC score	0.737000 (rank : 28)
Query Neighborhood Hits	113	Target Neighborhood Hits	693	Shared Neighborhood Hits	67
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_HUMAN
θ value	4.27553e-34 (rank : 24)	NC score	0.741600 (rank : 27)
Query Neighborhood Hits	113	Target Neighborhood Hits	663	Shared Neighborhood Hits	65
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

MOES_HUMAN
θ value	3.06405e-32 (rank : 25)	NC score	0.680190 (rank : 31)
Query Neighborhood Hits	113	Target Neighborhood Hits	892	Shared Neighborhood Hits	68
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_MOUSE
θ value	5.22648e-32 (rank : 26)	NC score	0.672830 (rank : 33)
Query Neighborhood Hits	113	Target Neighborhood Hits	923	Shared Neighborhood Hits	71
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

RADI_HUMAN
θ value	1.16434e-31 (rank : 27)	NC score	0.722230 (rank : 29)
Query Neighborhood Hits	113	Target Neighborhood Hits	741	Shared Neighborhood Hits	70
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	1.16434e-31 (rank : 28)	NC score	0.718479 (rank : 30)
Query Neighborhood Hits	113	Target Neighborhood Hits	773	Shared Neighborhood Hits	69
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

MERL_HUMAN
θ value	1.98606e-31 (rank : 29)	NC score	0.776156 (rank : 25)
Query Neighborhood Hits	113	Target Neighborhood Hits	532	Shared Neighborhood Hits	64
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	2.59387e-31 (rank : 30)	NC score	0.776577 (rank : 24)
Query Neighborhood Hits	113	Target Neighborhood Hits	524	Shared Neighborhood Hits	62
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

PTN14_MOUSE
θ value	4.14116e-29 (rank : 31)	NC score	0.600930 (rank : 40)
Query Neighborhood Hits	113	Target Neighborhood Hits	142	Shared Neighborhood Hits	48
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN14_HUMAN
θ value	1.2049e-28 (rank : 32)	NC score	0.593210 (rank : 41)
Query Neighborhood Hits	113	Target Neighborhood Hits	163	Shared Neighborhood Hits	48
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

MYLIP_HUMAN
θ value	1.73987e-27 (rank : 33)	NC score	0.846151 (rank : 17)
Query Neighborhood Hits	113	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_MOUSE
θ value	3.87602e-27 (rank : 34)	NC score	0.861451 (rank : 16)
Query Neighborhood Hits	113	Target Neighborhood Hits	139	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

PTN13_MOUSE
θ value	1.24688e-25 (rank : 35)	NC score	0.481767 (rank : 42)
Query Neighborhood Hits	113	Target Neighborhood Hits	426	Shared Neighborhood Hits	48
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN13_HUMAN
θ value	2.12685e-25 (rank : 36)	NC score	0.472655 (rank : 43)
Query Neighborhood Hits	113	Target Neighborhood Hits	471	Shared Neighborhood Hits	50
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

FRM4B_HUMAN
θ value	3.75424e-22 (rank : 37)	NC score	0.789774 (rank : 19)
Query Neighborhood Hits	113	Target Neighborhood Hits	117	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
θ value	4.15078e-21 (rank : 38)	NC score	0.787501 (rank : 20)
Query Neighborhood Hits	113	Target Neighborhood Hits	109	Shared Neighborhood Hits	50
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4A_MOUSE
θ value	1.02238e-19 (rank : 39)	NC score	0.778650 (rank : 21)
Query Neighborhood Hits	113	Target Neighborhood Hits	108	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_HUMAN
θ value	1.74391e-19 (rank : 40)	NC score	0.777230 (rank : 23)
Query Neighborhood Hits	113	Target Neighborhood Hits	110	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

TLN2_HUMAN
θ value	1.17247e-07 (rank : 41)	NC score	0.408703 (rank : 47)
Query Neighborhood Hits	113	Target Neighborhood Hits	157	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN2_MOUSE
θ value	1.99992e-07 (rank : 42)	NC score	0.412279 (rank : 46)
Query Neighborhood Hits	113	Target Neighborhood Hits	149	Shared Neighborhood Hits	51
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

FRMD6_MOUSE
θ value	2.61198e-07 (rank : 43)	NC score	0.659333 (rank : 34)
Query Neighborhood Hits	113	Target Neighborhood Hits	63	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRMD6_HUMAN
θ value	3.41135e-07 (rank : 44)	NC score	0.650338 (rank : 35)
Query Neighborhood Hits	113	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

FRMD1_HUMAN
θ value	4.45536e-07 (rank : 45)	NC score	0.638788 (rank : 37)
Query Neighborhood Hits	113	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

TLN1_HUMAN
θ value	4.45536e-07 (rank : 46)	NC score	0.417628 (rank : 44)
Query Neighborhood Hits	113	Target Neighborhood Hits	218	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	4.45536e-07 (rank : 47)	NC score	0.414456 (rank : 45)
Query Neighborhood Hits	113	Target Neighborhood Hits	213	Shared Neighborhood Hits	52
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

MTMR3_MOUSE
θ value	0.0330416 (rank : 48)	NC score	0.020542 (rank : 142)
Query Neighborhood Hits	113	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K296	Gene names	Mtmr3
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48).

KIF3A_HUMAN
θ value	0.0563607 (rank : 49)	NC score	0.024503 (rank : 140)
Query Neighborhood Hits	113	Target Neighborhood Hits	704	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

KIF3A_MOUSE
θ value	0.125558 (rank : 50)	NC score	0.027052 (rank : 137)
Query Neighborhood Hits	113	Target Neighborhood Hits	715	Shared Neighborhood Hits	30
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

ALS2_HUMAN
θ value	0.21417 (rank : 51)	NC score	0.039458 (rank : 127)
Query Neighborhood Hits	113	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

TITIN_HUMAN
θ value	0.21417 (rank : 52)	NC score	0.009855 (rank : 163)
Query Neighborhood Hits	113	Target Neighborhood Hits	2923	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

KIRR1_MOUSE
θ value	0.279714 (rank : 53)	NC score	0.011143 (rank : 159)
Query Neighborhood Hits	113	Target Neighborhood Hits	403	Shared Neighborhood Hits	4
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

NASP_HUMAN
θ value	0.279714 (rank : 54)	NC score	0.053543 (rank : 117)
Query Neighborhood Hits	113	Target Neighborhood Hits	709	Shared Neighborhood Hits	22
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

CP250_HUMAN
θ value	0.365318 (rank : 55)	NC score	0.031747 (rank : 133)
Query Neighborhood Hits	113	Target Neighborhood Hits	1805	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

POK17_HUMAN
θ value	0.365318 (rank : 56)	NC score	0.018555 (rank : 147)
Query Neighborhood Hits	113	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	P63136	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Pol protein [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

MAP1A_HUMAN
θ value	0.47712 (rank : 57)	NC score	0.046767 (rank : 124)
Query Neighborhood Hits	113	Target Neighborhood Hits	1626	Shared Neighborhood Hits	43
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

POK5_HUMAN
θ value	0.47712 (rank : 58)	NC score	0.018308 (rank : 150)
Query Neighborhood Hits	113	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	P63132	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Pol protein (HERV-K113 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK6_HUMAN
θ value	0.47712 (rank : 59)	NC score	0.018316 (rank : 149)
Query Neighborhood Hits	113	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	P63133	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Pol protein (HERV-K115 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

ACHA4_HUMAN
θ value	0.813845 (rank : 60)	NC score	0.003953 (rank : 177)
Query Neighborhood Hits	113	Target Neighborhood Hits	131	Shared Neighborhood Hits	2
SwissProt Accessions	P43681, Q4JGR7	Gene names	CHRNA4, NACRA4
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-4 precursor.

SEC63_MOUSE
θ value	0.813845 (rank : 61)	NC score	0.016064 (rank : 154)
Query Neighborhood Hits	113	Target Neighborhood Hits	601	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

CS007_HUMAN
θ value	1.06291 (rank : 62)	NC score	0.012176 (rank : 156)
Query Neighborhood Hits	113	Target Neighborhood Hits	401	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

EP15_HUMAN
θ value	1.06291 (rank : 63)	NC score	0.019073 (rank : 145)
Query Neighborhood Hits	113	Target Neighborhood Hits	1021	Shared Neighborhood Hits	31
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EP15_MOUSE
θ value	1.06291 (rank : 64)	NC score	0.011484 (rank : 158)
Query Neighborhood Hits	113	Target Neighborhood Hits	820	Shared Neighborhood Hits	24
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

M3K12_HUMAN
θ value	1.06291 (rank : 65)	NC score	-0.001921 (rank : 183)
Query Neighborhood Hits	113	Target Neighborhood Hits	940	Shared Neighborhood Hits	9
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

MD1L1_MOUSE
θ value	1.06291 (rank : 66)	NC score	0.033851 (rank : 131)
Query Neighborhood Hits	113	Target Neighborhood Hits	1001	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

CJ068_HUMAN
θ value	1.38821 (rank : 67)	NC score	0.035652 (rank : 130)
Query Neighborhood Hits	113	Target Neighborhood Hits	316	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

KIRR1_HUMAN
θ value	1.38821 (rank : 68)	NC score	0.009363 (rank : 165)
Query Neighborhood Hits	113	Target Neighborhood Hits	401	Shared Neighborhood Hits	4
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

REST_MOUSE
θ value	1.38821 (rank : 69)	NC score	0.027649 (rank : 136)
Query Neighborhood Hits	113	Target Neighborhood Hits	1506	Shared Neighborhood Hits	41
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

MIER1_HUMAN
θ value	1.81305 (rank : 70)	NC score	0.012532 (rank : 155)
Query Neighborhood Hits	113	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N108, Q5T104, Q6AHY8, Q86TB4, Q8N156, Q8N161, Q8NC37, Q8NES4, Q8NES5, Q8NES6, Q8WWG2, Q9HCG2	Gene names	MIER1, KIAA1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1) (hmi-er1) (Early response 1) (Er1).

NEK1_MOUSE
θ value	1.81305 (rank : 71)	NC score	-0.001934 (rank : 184)
Query Neighborhood Hits	113	Target Neighborhood Hits	1311	Shared Neighborhood Hits	24
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

PF21B_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.008503 (rank : 169)
Query Neighborhood Hits	113	Target Neighborhood Hits	197	Shared Neighborhood Hits	6
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

RAD50_HUMAN
θ value	1.81305 (rank : 73)	NC score	0.024423 (rank : 141)
Query Neighborhood Hits	113	Target Neighborhood Hits	1317	Shared Neighborhood Hits	39
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

ZN638_HUMAN
θ value	1.81305 (rank : 74)	NC score	0.010909 (rank : 160)
Query Neighborhood Hits	113	Target Neighborhood Hits	343	Shared Neighborhood Hits	11
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

GOGA5_MOUSE
θ value	2.36792 (rank : 75)	NC score	0.037725 (rank : 129)
Query Neighborhood Hits	113	Target Neighborhood Hits	1434	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

PKHC1_MOUSE
θ value	2.36792 (rank : 76)	NC score	0.040466 (rank : 126)
Query Neighborhood Hits	113	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CIB5, Q8C542, Q8K035	Gene names	Plekhc1
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1.

TSH3_MOUSE
θ value	2.36792 (rank : 77)	NC score	0.006307 (rank : 172)
Query Neighborhood Hits	113	Target Neighborhood Hits	590	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

BPA1_MOUSE
θ value	3.0926 (rank : 78)	NC score	0.019812 (rank : 143)
Query Neighborhood Hits	113	Target Neighborhood Hits	1477	Shared Neighborhood Hits	40
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

IKKB_HUMAN
θ value	3.0926 (rank : 79)	NC score	-0.002961 (rank : 185)
Query Neighborhood Hits	113	Target Neighborhood Hits	980	Shared Neighborhood Hits	15
SwissProt Accessions	O14920, O75327	Gene names	IKBKB, IKKB
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

MYCB2_HUMAN
θ value	3.0926 (rank : 80)	NC score	0.009974 (rank : 162)
Query Neighborhood Hits	113	Target Neighborhood Hits	390	Shared Neighborhood Hits	12
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

PKHC1_HUMAN
θ value	3.0926 (rank : 81)	NC score	0.042273 (rank : 125)
Query Neighborhood Hits	113	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q96AC1, Q14840, Q86TY7	Gene names	PLEKHC1, KIND2, MIG2
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1 (Kindlin-2) (Mitogen-inducible gene 2 protein) (Mig-2).

REST_HUMAN
θ value	3.0926 (rank : 82)	NC score	0.032445 (rank : 132)
Query Neighborhood Hits	113	Target Neighborhood Hits	1605	Shared Neighborhood Hits	42
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SEC63_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.016787 (rank : 152)
Query Neighborhood Hits	113	Target Neighborhood Hits	586	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

ZNFX1_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.007931 (rank : 170)
Query Neighborhood Hits	113	Target Neighborhood Hits	308	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

BSN_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.018580 (rank : 146)
Query Neighborhood Hits	113	Target Neighborhood Hits	1537	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CENPE_HUMAN
θ value	4.03905 (rank : 86)	NC score	0.029452 (rank : 134)
Query Neighborhood Hits	113	Target Neighborhood Hits	2060	Shared Neighborhood Hits	48
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

DMD_MOUSE
θ value	4.03905 (rank : 87)	NC score	0.018419 (rank : 148)
Query Neighborhood Hits	113	Target Neighborhood Hits	1111	Shared Neighborhood Hits	34
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

HAP1_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.039089 (rank : 128)
Query Neighborhood Hits	113	Target Neighborhood Hits	606	Shared Neighborhood Hits	28
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

MORC3_HUMAN
θ value	4.03905 (rank : 89)	NC score	0.025003 (rank : 139)
Query Neighborhood Hits	113	Target Neighborhood Hits	489	Shared Neighborhood Hits	21
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

POK3_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.016232 (rank : 153)
Query Neighborhood Hits	113	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WJR5, O15312	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Pol protein (HERV-K(C19) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

ZHX1_MOUSE
θ value	4.03905 (rank : 91)	NC score	0.009764 (rank : 164)
Query Neighborhood Hits	113	Target Neighborhood Hits	334	Shared Neighborhood Hits	7
SwissProt Accessions	P70121, Q8BQ68, Q8C6T4, Q8CJG3	Gene names	Zhx1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

ANR38_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.002425 (rank : 180)
Query Neighborhood Hits	113	Target Neighborhood Hits	443	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

LAMC1_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.006876 (rank : 171)
Query Neighborhood Hits	113	Target Neighborhood Hits	922	Shared Neighborhood Hits	27
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

M3K12_MOUSE
θ value	5.27518 (rank : 94)	NC score	-0.003548 (rank : 187)
Query Neighborhood Hits	113	Target Neighborhood Hits	957	Shared Neighborhood Hits	8
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

MKS1_MOUSE
θ value	5.27518 (rank : 95)	NC score	0.008666 (rank : 167)
Query Neighborhood Hits	113	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SW45, Q3V3W3	Gene names	Mks1
Domain Architecture	No domain graphic available
Description	Meckel syndrome type 1 protein homolog.

NALP5_MOUSE
θ value	5.27518 (rank : 96)	NC score	0.011861 (rank : 157)
Query Neighborhood Hits	113	Target Neighborhood Hits	560	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

SPRL1_HUMAN
θ value	5.27518 (rank : 97)	NC score	0.017721 (rank : 151)
Query Neighborhood Hits	113	Target Neighborhood Hits	231	Shared Neighborhood Hits	18
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

ZHX1_HUMAN
θ value	5.27518 (rank : 98)	NC score	0.009086 (rank : 166)
Query Neighborhood Hits	113	Target Neighborhood Hits	307	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKY1, Q8IWD8	Gene names	ZHX1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

ZN560_HUMAN
θ value	5.27518 (rank : 99)	NC score	-0.005281 (rank : 188)
Query Neighborhood Hits	113	Target Neighborhood Hits	751	Shared Neighborhood Hits	5
SwissProt Accessions	Q96MR9, Q495S9, Q495T1	Gene names	ZNF560
Domain Architecture	No domain graphic available
Description	Zinc finger protein 560.

CS007_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.008604 (rank : 168)
Query Neighborhood Hits	113	Target Neighborhood Hits	464	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

MYH11_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.019643 (rank : 144)
Query Neighborhood Hits	113	Target Neighborhood Hits	1806	Shared Neighborhood Hits	43
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

RAE2_MOUSE
θ value	6.88961 (rank : 102)	NC score	0.004457 (rank : 174)
Query Neighborhood Hits	113	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZD5, Q8CH16	Gene names	Chml, Rep2
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 2 (Rab escort protein 2) (REP-2) (Choroideraemia-like protein).

RTN1_MOUSE
θ value	6.88961 (rank : 103)	NC score	0.004211 (rank : 176)
Query Neighborhood Hits	113	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

ANK1_MOUSE
θ value	8.99809 (rank : 104)	NC score	-0.001600 (rank : 182)
Query Neighborhood Hits	113	Target Neighborhood Hits	430	Shared Neighborhood Hits	6
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANR35_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.000730 (rank : 181)
Query Neighborhood Hits	113	Target Neighborhood Hits	784	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

CENPF_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.026130 (rank : 138)
Query Neighborhood Hits	113	Target Neighborhood Hits	1932	Shared Neighborhood Hits	44
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

ERCC2_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.010140 (rank : 161)
Query Neighborhood Hits	113	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P18074, Q8N721	Gene names	ERCC2, XPD, XPDC
Domain Architecture
Description	TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-) (DNA-repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein) (CXPD) (DNA excision repair protein ERCC-2).

ETV3_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.002855 (rank : 179)
Query Neighborhood Hits	113	Target Neighborhood Hits	312	Shared Neighborhood Hits	5
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

IWS1_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.029080 (rank : 135)
Query Neighborhood Hits	113	Target Neighborhood Hits	1241	Shared Neighborhood Hits	33
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NELFA_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.004287 (rank : 175)
Query Neighborhood Hits	113	Target Neighborhood Hits	195	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

NRK_HUMAN
θ value	8.99809 (rank : 111)	NC score	-0.003152 (rank : 186)
Query Neighborhood Hits	113	Target Neighborhood Hits	931	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

TSH3_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.003917 (rank : 178)
Query Neighborhood Hits	113	Target Neighborhood Hits	564	Shared Neighborhood Hits	7
SwissProt Accessions	Q63HK5, Q9H0G6, Q9P254	Gene names	TSHZ3, KIAA1474, TSH3, ZNF537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

ZNFX1_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.006257 (rank : 173)
Query Neighborhood Hits	113	Target Neighborhood Hits	407	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ARHG4_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.050777 (rank : 123)
Query Neighborhood Hits	113	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

ARHG4_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.052013 (rank : 120)
Query Neighborhood Hits	113	Target Neighborhood Hits	185	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

CA106_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.084749 (rank : 92)
Query Neighborhood Hits	113	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.083605 (rank : 93)
Query Neighborhood Hits	113	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

CD45_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.098919 (rank : 82)
Query Neighborhood Hits	113	Target Neighborhood Hits	243	Shared Neighborhood Hits	10
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD45_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.103952 (rank : 71)
Query Neighborhood Hits	113	Target Neighborhood Hits	178	Shared Neighborhood Hits	13
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

FGD1_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.059049 (rank : 112)
Query Neighborhood Hits	113	Target Neighborhood Hits	367	Shared Neighborhood Hits	11
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.057136 (rank : 113)
Query Neighborhood Hits	113	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD2_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.050977 (rank : 122)
Query Neighborhood Hits	113	Target Neighborhood Hits	151	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

FGD2_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.055516 (rank : 116)
Query Neighborhood Hits	113	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

FGD3_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.053473 (rank : 118)
Query Neighborhood Hits	113	Target Neighborhood Hits	249	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

FGD3_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.051941 (rank : 121)
Query Neighborhood Hits	113	Target Neighborhood Hits	257	Shared Neighborhood Hits	4
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD4_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.060927 (rank : 109)
Query Neighborhood Hits	113	Target Neighborhood Hits	219	Shared Neighborhood Hits	6
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD4_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.061586 (rank : 108)
Query Neighborhood Hits	113	Target Neighborhood Hits	227	Shared Neighborhood Hits	7
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD5_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.064385 (rank : 105)
Query Neighborhood Hits	113	Target Neighborhood Hits	235	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD5_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.060673 (rank : 110)
Query Neighborhood Hits	113	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

FGD6_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.063473 (rank : 106)
Query Neighborhood Hits	113	Target Neighborhood Hits	237	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.062436 (rank : 107)
Query Neighborhood Hits	113	Target Neighborhood Hits	282	Shared Neighborhood Hits	6
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

HIP1R_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.056460 (rank : 114)
Query Neighborhood Hits	113	Target Neighborhood Hits	809	Shared Neighborhood Hits	35
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1R_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.052634 (rank : 119)
Query Neighborhood Hits	113	Target Neighborhood Hits	959	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

HIP1_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.059509 (rank : 111)
Query Neighborhood Hits	113	Target Neighborhood Hits	1016	Shared Neighborhood Hits	38
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

KRIT1_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.083003 (rank : 96)
Query Neighborhood Hits	113	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

KRIT1_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.077044 (rank : 100)
Query Neighborhood Hits	113	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

PKHA6_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.056216 (rank : 115)
Query Neighborhood Hits	113	Target Neighborhood Hits	591	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PTN11_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.102459 (rank : 77)
Query Neighborhood Hits	113	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.102450 (rank : 78)
Query Neighborhood Hits	113	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN12_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.109094 (rank : 59)
Query Neighborhood Hits	113	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.108787 (rank : 63)
Query Neighborhood Hits	113	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN18_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.117921 (rank : 50)
Query Neighborhood Hits	113	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.114401 (rank : 53)
Query Neighborhood Hits	113	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN1_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.117876 (rank : 52)
Query Neighborhood Hits	113	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.118248 (rank : 49)
Query Neighborhood Hits	113	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN22_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.110729 (rank : 56)
Query Neighborhood Hits	113	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN22_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.109030 (rank : 60)
Query Neighborhood Hits	113	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN23_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.102992 (rank : 73)
Query Neighborhood Hits	113	Target Neighborhood Hits	646	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.101358 (rank : 80)
Query Neighborhood Hits	113	Target Neighborhood Hits	726	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN2_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.117882 (rank : 51)
Query Neighborhood Hits	113	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN2_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.119137 (rank : 48)
Query Neighborhood Hits	113	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN5_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.102473 (rank : 76)
Query Neighborhood Hits	113	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.102478 (rank : 75)
Query Neighborhood Hits	113	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN6_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.108923 (rank : 61)
Query Neighborhood Hits	113	Target Neighborhood Hits	234	Shared Neighborhood Hits	8
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.108896 (rank : 62)
Query Neighborhood Hits	113	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN7_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.109164 (rank : 58)
Query Neighborhood Hits	113	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.110328 (rank : 57)
Query Neighborhood Hits	113	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN9_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.113953 (rank : 54)
Query Neighborhood Hits	113	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.113586 (rank : 55)
Query Neighborhood Hits	113	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPR2_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.106930 (rank : 65)
Query Neighborhood Hits	113	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.106756 (rank : 66)
Query Neighborhood Hits	113	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRA_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.095175 (rank : 84)
Query Neighborhood Hits	113	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.095139 (rank : 85)
Query Neighborhood Hits	113	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRB_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.100534 (rank : 81)
Query Neighborhood Hits	113	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRD_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.067627 (rank : 102)
Query Neighborhood Hits	113	Target Neighborhood Hits	485	Shared Neighborhood Hits	12
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.065206 (rank : 104)
Query Neighborhood Hits	113	Target Neighborhood Hits	491	Shared Neighborhood Hits	12
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRE_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.095515 (rank : 83)
Query Neighborhood Hits	113	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.095033 (rank : 86)
Query Neighborhood Hits	113	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRF_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.065977 (rank : 103)
Query Neighborhood Hits	113	Target Neighborhood Hits	489	Shared Neighborhood Hits	11
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRG_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.085389 (rank : 90)
Query Neighborhood Hits	113	Target Neighborhood Hits	231	Shared Neighborhood Hits	13
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.085559 (rank : 89)
Query Neighborhood Hits	113	Target Neighborhood Hits	260	Shared Neighborhood Hits	15
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRJ_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.102895 (rank : 74)
Query Neighborhood Hits	113	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRJ_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.103133 (rank : 72)
Query Neighborhood Hits	113	Target Neighborhood Hits	188	Shared Neighborhood Hits	10
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRK_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.086070 (rank : 88)
Query Neighborhood Hits	113	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.086776 (rank : 87)
Query Neighborhood Hits	113	Target Neighborhood Hits	223	Shared Neighborhood Hits	9
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRM_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.081102 (rank : 98)
Query Neighborhood Hits	113	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.081414 (rank : 97)
Query Neighborhood Hits	113	Target Neighborhood Hits	238	Shared Neighborhood Hits	9
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRN_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.106493 (rank : 67)
Query Neighborhood Hits	113	Target Neighborhood Hits	156	Shared Neighborhood Hits	9
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.106096 (rank : 68)
Query Neighborhood Hits	113	Target Neighborhood Hits	240	Shared Neighborhood Hits	10
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRO_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.107185 (rank : 64)
Query Neighborhood Hits	113	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRR_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.104368 (rank : 70)
Query Neighborhood Hits	113	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.104711 (rank : 69)
Query Neighborhood Hits	113	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRS_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.068709 (rank : 101)
Query Neighborhood Hits	113	Target Neighborhood Hits	472	Shared Neighborhood Hits	11
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRT_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.083240 (rank : 94)
Query Neighborhood Hits	113	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.083196 (rank : 95)
Query Neighborhood Hits	113	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRU_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.080940 (rank : 99)
Query Neighborhood Hits	113	Target Neighborhood Hits	237	Shared Neighborhood Hits	10
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRV_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.102046 (rank : 79)
Query Neighborhood Hits	113	Target Neighborhood Hits	179	Shared Neighborhood Hits	10
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRZ_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.085244 (rank : 91)
Query Neighborhood Hits	113	Target Neighborhood Hits	255	Shared Neighborhood Hits	10
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

Hits sorted by NC score

E41L3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41L1_MOUSE
NC score	0.986219 (rank : 2)	θ value	5.01279e-176 (rank : 4)
Query Neighborhood Hits	113	Target Neighborhood Hits	106	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

41_HUMAN
NC score	0.981257 (rank : 3)	θ value	1.20145e-153 (rank : 7)
Query Neighborhood Hits	113	Target Neighborhood Hits	157	Shared Neighborhood Hits	49
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

E41L3_MOUSE
NC score	0.980983 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	113	Target Neighborhood Hits	250	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L1_HUMAN
NC score	0.980953 (rank : 5)	θ value	1.72287e-176 (rank : 3)
Query Neighborhood Hits	113	Target Neighborhood Hits	180	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

41_MOUSE
NC score	0.979422 (rank : 6)	θ value	4.88915e-147 (rank : 8)
Query Neighborhood Hits	113	Target Neighborhood Hits	184	Shared Neighborhood Hits	52
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

E41L2_HUMAN
NC score	0.973318 (rank : 7)	θ value	3.72618e-163 (rank : 5)
Query Neighborhood Hits	113	Target Neighborhood Hits	287	Shared Neighborhood Hits	61
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L5_HUMAN
NC score	0.965636 (rank : 8)	θ value	8.51556e-75 (rank : 10)
Query Neighborhood Hits	113	Target Neighborhood Hits	76	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LB_MOUSE
NC score	0.965511 (rank : 9)	θ value	1.35953e-72 (rank : 11)
Query Neighborhood Hits	113	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

FRMD5_MOUSE
NC score	0.963951 (rank : 10)	θ value	1.11475e-66 (rank : 18)
Query Neighborhood Hits	113	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_HUMAN
NC score	0.961235 (rank : 11)	θ value	1.2325e-65 (rank : 19)
Query Neighborhood Hits	113	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41LB_HUMAN
NC score	0.959377 (rank : 12)	θ value	6.7473e-72 (rank : 12)
Query Neighborhood Hits	113	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

E41LA_HUMAN
NC score	0.958406 (rank : 13)	θ value	3.70236e-70 (rank : 14)
Query Neighborhood Hits	113	Target Neighborhood Hits	87	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_MOUSE
NC score	0.958094 (rank : 14)	θ value	1.11475e-66 (rank : 17)
Query Neighborhood Hits	113	Target Neighborhood Hits	85	Shared Neighborhood Hits	48
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41L2_MOUSE
NC score	0.952375 (rank : 15)	θ value	9.49765e-159 (rank : 6)
Query Neighborhood Hits	113	Target Neighborhood Hits	459	Shared Neighborhood Hits	61
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MYLIP_MOUSE
NC score	0.861451 (rank : 16)	θ value	3.87602e-27 (rank : 34)
Query Neighborhood Hits	113	Target Neighborhood Hits	139	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_HUMAN
NC score	0.846151 (rank : 17)	θ value	1.73987e-27 (rank : 33)
Query Neighborhood Hits	113	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

FARP1_HUMAN
NC score	0.802663 (rank : 18)	θ value	1.27248e-70 (rank : 13)
Query Neighborhood Hits	113	Target Neighborhood Hits	241	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FRM4B_HUMAN
NC score	0.789774 (rank : 19)	θ value	3.75424e-22 (rank : 37)
Query Neighborhood Hits	113	Target Neighborhood Hits	117	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
NC score	0.787501 (rank : 20)	θ value	4.15078e-21 (rank : 38)
Query Neighborhood Hits	113	Target Neighborhood Hits	109	Shared Neighborhood Hits	50
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4A_MOUSE
NC score	0.778650 (rank : 21)	θ value	1.02238e-19 (rank : 39)
Query Neighborhood Hits	113	Target Neighborhood Hits	108	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FARP2_HUMAN
NC score	0.778548 (rank : 22)	θ value	1.31681e-67 (rank : 16)
Query Neighborhood Hits	113	Target Neighborhood Hits	240	Shared Neighborhood Hits	48
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FRM4A_HUMAN
NC score	0.777230 (rank : 23)	θ value	1.74391e-19 (rank : 40)
Query Neighborhood Hits	113	Target Neighborhood Hits	110	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

MERL_MOUSE
NC score	0.776577 (rank : 24)	θ value	2.59387e-31 (rank : 30)
Query Neighborhood Hits	113	Target Neighborhood Hits	524	Shared Neighborhood Hits	62
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MERL_HUMAN
NC score	0.776156 (rank : 25)	θ value	1.98606e-31 (rank : 29)
Query Neighborhood Hits	113	Target Neighborhood Hits	532	Shared Neighborhood Hits	64
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

FARP2_MOUSE
NC score	0.770864 (rank : 26)	θ value	2.3998e-69 (rank : 15)
Query Neighborhood Hits	113	Target Neighborhood Hits	209	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

EZRI_HUMAN
NC score	0.741600 (rank : 27)	θ value	4.27553e-34 (rank : 24)
Query Neighborhood Hits	113	Target Neighborhood Hits	663	Shared Neighborhood Hits	65
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
NC score	0.737000 (rank : 28)	θ value	1.46948e-34 (rank : 23)
Query Neighborhood Hits	113	Target Neighborhood Hits	693	Shared Neighborhood Hits	67
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

RADI_HUMAN
NC score	0.722230 (rank : 29)	θ value	1.16434e-31 (rank : 27)
Query Neighborhood Hits	113	Target Neighborhood Hits	741	Shared Neighborhood Hits	70
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
NC score	0.718479 (rank : 30)	θ value	1.16434e-31 (rank : 28)
Query Neighborhood Hits	113	Target Neighborhood Hits	773	Shared Neighborhood Hits	69
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

MOES_HUMAN
NC score	0.680190 (rank : 31)	θ value	3.06405e-32 (rank : 25)
Query Neighborhood Hits	113	Target Neighborhood Hits	892	Shared Neighborhood Hits	68
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

PTN4_HUMAN
NC score	0.678999 (rank : 32)	θ value	7.68416e-84 (rank : 9)
Query Neighborhood Hits	113	Target Neighborhood Hits	303	Shared Neighborhood Hits	49
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

MOES_MOUSE
NC score	0.672830 (rank : 33)	θ value	5.22648e-32 (rank : 26)
Query Neighborhood Hits	113	Target Neighborhood Hits	923	Shared Neighborhood Hits	71
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

FRMD6_MOUSE
NC score	0.659333 (rank : 34)	θ value	2.61198e-07 (rank : 43)
Query Neighborhood Hits	113	Target Neighborhood Hits	63	Shared Neighborhood Hits	44
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRMD6_HUMAN
NC score	0.650338 (rank : 35)	θ value	3.41135e-07 (rank : 44)
Query Neighborhood Hits	113	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

PTN3_HUMAN
NC score	0.649843 (rank : 36)	θ value	4.24587e-58 (rank : 20)
Query Neighborhood Hits	113	Target Neighborhood Hits	258	Shared Neighborhood Hits	47
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

FRMD1_HUMAN
NC score	0.638788 (rank : 37)	θ value	4.45536e-07 (rank : 45)
Query Neighborhood Hits	113	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

PTN21_MOUSE
NC score	0.621864 (rank : 38)	θ value	1.79215e-40 (rank : 21)
Query Neighborhood Hits	113	Target Neighborhood Hits	155	Shared Neighborhood Hits	48
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
NC score	0.620046 (rank : 39)	θ value	2.34062e-40 (rank : 22)
Query Neighborhood Hits	113	Target Neighborhood Hits	143	Shared Neighborhood Hits	47
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN14_MOUSE
NC score	0.600930 (rank : 40)	θ value	4.14116e-29 (rank : 31)
Query Neighborhood Hits	113	Target Neighborhood Hits	142	Shared Neighborhood Hits	48
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN14_HUMAN
NC score	0.593210 (rank : 41)	θ value	1.2049e-28 (rank : 32)
Query Neighborhood Hits	113	Target Neighborhood Hits	163	Shared Neighborhood Hits	48
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN13_MOUSE
NC score	0.481767 (rank : 42)	θ value	1.24688e-25 (rank : 35)
Query Neighborhood Hits	113	Target Neighborhood Hits	426	Shared Neighborhood Hits	48
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN13_HUMAN
NC score	0.472655 (rank : 43)	θ value	2.12685e-25 (rank : 36)
Query Neighborhood Hits	113	Target Neighborhood Hits	471	Shared Neighborhood Hits	50
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

TLN1_HUMAN
NC score	0.417628 (rank : 44)	θ value	4.45536e-07 (rank : 46)
Query Neighborhood Hits	113	Target Neighborhood Hits	218	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
NC score	0.414456 (rank : 45)	θ value	4.45536e-07 (rank : 47)
Query Neighborhood Hits	113	Target Neighborhood Hits	213	Shared Neighborhood Hits	52
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN2_MOUSE
NC score	0.412279 (rank : 46)	θ value	1.99992e-07 (rank : 42)
Query Neighborhood Hits	113	Target Neighborhood Hits	149	Shared Neighborhood Hits	51
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN2_HUMAN
NC score	0.408703 (rank : 47)	θ value	1.17247e-07 (rank : 41)
Query Neighborhood Hits	113	Target Neighborhood Hits	157	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

PTN2_MOUSE
NC score	0.119137 (rank : 48)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	113	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN1_MOUSE
NC score	0.118248 (rank : 49)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	113	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN18_HUMAN
NC score	0.117921 (rank : 50)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	113	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN2_HUMAN
NC score	0.117882 (rank : 51)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	113	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN1_HUMAN
NC score	0.117876 (rank : 52)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	113	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN18_MOUSE
NC score	0.114401 (rank : 53)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	113	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN9_HUMAN
NC score	0.113953 (rank : 54)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	113	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
NC score	0.113586 (rank : 55)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	113	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN22_HUMAN
NC score	0.110729 (rank : 56)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	113	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN7_MOUSE
NC score	0.110328 (rank : 57)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	113	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN7_HUMAN
NC score	0.109164 (rank : 58)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	113	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN12_HUMAN
NC score	0.109094 (rank : 59)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	113	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN22_MOUSE
NC score	0.109030 (rank : 60)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	113	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN6_HUMAN
NC score	0.108923 (rank : 61)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	113	Target Neighborhood Hits	234	Shared Neighborhood Hits	8
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
NC score	0.108896 (rank : 62)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	113	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN12_MOUSE
NC score	0.108787 (rank : 63)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	113	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTPRO_HUMAN
NC score	0.107185 (rank : 64)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	113	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPR2_HUMAN
NC score	0.106930 (rank : 65)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	113	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
NC score	0.106756 (rank : 66)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	113	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRN_HUMAN
NC score	0.106493 (rank : 67)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	113	Target Neighborhood Hits	156	Shared Neighborhood Hits	9
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
NC score	0.106096 (rank : 68)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	113	Target Neighborhood Hits	240	Shared Neighborhood Hits	10
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRR_MOUSE
NC score	0.104711 (rank : 69)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	113	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRR_HUMAN
NC score	0.104368 (rank : 70)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	113	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

CD45_MOUSE
NC score	0.103952 (rank : 71)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	113	Target Neighborhood Hits	178	Shared Neighborhood Hits	13
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTPRJ_MOUSE
NC score	0.103133 (rank : 72)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	113	Target Neighborhood Hits	188	Shared Neighborhood Hits	10
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTN23_HUMAN
NC score	0.102992 (rank : 73)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	113	Target Neighborhood Hits	646	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTPRJ_HUMAN
NC score	0.102895 (rank : 74)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	113	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTN5_MOUSE
NC score	0.102478 (rank : 75)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	113	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_HUMAN
NC score	0.102473 (rank : 76)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	113	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN11_HUMAN
NC score	0.102459 (rank : 77)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	113	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
NC score	0.102450 (rank : 78)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	113	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTPRV_MOUSE
NC score	0.102046 (rank : 79)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	113	Target Neighborhood Hits	179	Shared Neighborhood Hits	10
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTN23_MOUSE
NC score	0.101358 (rank : 80)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	113	Target Neighborhood Hits	726	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTPRB_HUMAN
NC score	0.100534 (rank : 81)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	113	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

CD45_HUMAN
NC score	0.098919 (rank : 82)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	113	Target Neighborhood Hits	243	Shared Neighborhood Hits	10
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTPRE_HUMAN
NC score	0.095515 (rank : 83)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	113	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_HUMAN
NC score	0.095175 (rank : 84)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	113	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
NC score	0.095139 (rank : 85)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	113	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRE_MOUSE
NC score	0.095033 (rank : 86)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	113	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRK_MOUSE
NC score	0.086776 (rank : 87)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	113	Target Neighborhood Hits	223	Shared Neighborhood Hits	9
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_HUMAN
NC score	0.086070 (rank : 88)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	113	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRG_MOUSE
NC score	0.085559 (rank : 89)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	113	Target Neighborhood Hits	260	Shared Neighborhood Hits	15
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_HUMAN
NC score	0.085389 (rank : 90)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	113	Target Neighborhood Hits	231	Shared Neighborhood Hits	13
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRZ_HUMAN
NC score	0.085244 (rank : 91)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	113	Target Neighborhood Hits	255	Shared Neighborhood Hits	10
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

CA106_HUMAN
NC score	0.084749 (rank : 92)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	113	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
NC score	0.083605 (rank : 93)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	113	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

PTPRT_HUMAN
NC score	0.083240 (rank : 94)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	113	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
NC score	0.083196 (rank : 95)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	113	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

KRIT1_HUMAN
NC score	0.083003 (rank : 96)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	113	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

PTPRM_MOUSE
NC score	0.081414 (rank : 97)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	113	Target Neighborhood Hits	238	Shared Neighborhood Hits	9
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_HUMAN
NC score	0.081102 (rank : 98)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	113	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRU_HUMAN
NC score	0.080940 (rank : 99)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	113	Target Neighborhood Hits	237	Shared Neighborhood Hits	10
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

KRIT1_MOUSE
NC score	0.077044 (rank : 100)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	113	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

PTPRS_HUMAN
NC score	0.068709 (rank : 101)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	113	Target Neighborhood Hits	472	Shared Neighborhood Hits	11
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRD_HUMAN
NC score	0.067627 (rank : 102)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	113	Target Neighborhood Hits	485	Shared Neighborhood Hits	12
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRF_HUMAN
NC score	0.065977 (rank : 103)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	113	Target Neighborhood Hits	489	Shared Neighborhood Hits	11
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRD_MOUSE
NC score	0.065206 (rank : 104)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	113	Target Neighborhood Hits	491	Shared Neighborhood Hits	12
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

FGD5_HUMAN
NC score	0.064385 (rank : 105)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	113	Target Neighborhood Hits	235	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

FGD6_HUMAN
NC score	0.063473 (rank : 106)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	113	Target Neighborhood Hits	237	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
NC score	0.062436 (rank : 107)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	113	Target Neighborhood Hits	282	Shared Neighborhood Hits	6
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FGD4_MOUSE
NC score	0.061586 (rank : 108)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	113	Target Neighborhood Hits	227	Shared Neighborhood Hits	7
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

FGD4_HUMAN
NC score	0.060927 (rank : 109)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	113	Target Neighborhood Hits	219	Shared Neighborhood Hits	6
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FGD5_MOUSE
NC score	0.060673 (rank : 110)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	113	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

HIP1_HUMAN
NC score	0.059509 (rank : 111)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	113	Target Neighborhood Hits	1016	Shared Neighborhood Hits	38
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

FGD1_HUMAN
NC score	0.059049 (rank : 112)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	113	Target Neighborhood Hits	367	Shared Neighborhood Hits	11
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
NC score	0.057136 (rank : 113)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	113	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

HIP1R_HUMAN
NC score	0.056460 (rank : 114)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	113	Target Neighborhood Hits	809	Shared Neighborhood Hits	35
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

PKHA6_MOUSE
NC score	0.056216 (rank : 115)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	113	Target Neighborhood Hits	591	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

FGD2_MOUSE
NC score	0.055516 (rank : 116)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	113	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

NASP_HUMAN
NC score	0.053543 (rank : 117)	θ value	0.279714 (rank : 54)
Query Neighborhood Hits	113	Target Neighborhood Hits	709	Shared Neighborhood Hits	22
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

FGD3_HUMAN
NC score	0.053473 (rank : 118)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	113	Target Neighborhood Hits	249	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

HIP1R_MOUSE
NC score	0.052634 (rank : 119)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	113	Target Neighborhood Hits	959	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

ARHG4_MOUSE
NC score	0.052013 (rank : 120)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	113	Target Neighborhood Hits	185	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TNR9, Q80TJ6	Gene names	Arhgef4, Kiaa1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

FGD3_MOUSE
NC score	0.051941 (rank : 121)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	113	Target Neighborhood Hits	257	Shared Neighborhood Hits	4
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

FGD2_HUMAN
NC score	0.050977 (rank : 122)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	113	Target Neighborhood Hits	151	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

ARHG4_HUMAN
NC score	0.050777 (rank : 123)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	113	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

MAP1A_HUMAN
NC score	0.046767 (rank : 124)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	113	Target Neighborhood Hits	1626	Shared Neighborhood Hits	43
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PKHC1_HUMAN
NC score	0.042273 (rank : 125)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	113	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q96AC1, Q14840, Q86TY7	Gene names	PLEKHC1, KIND2, MIG2
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1 (Kindlin-2) (Mitogen-inducible gene 2 protein) (Mig-2).

PKHC1_MOUSE
NC score	0.040466 (rank : 126)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	113	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CIB5, Q8C542, Q8K035	Gene names	Plekhc1
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1.

ALS2_HUMAN
NC score	0.039458 (rank : 127)	θ value	0.21417 (rank : 51)
Query Neighborhood Hits	113	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9	Gene names	ALS2, KIAA1563
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2).

HAP1_HUMAN
NC score	0.039089 (rank : 128)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	113	Target Neighborhood Hits	606	Shared Neighborhood Hits	28
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

GOGA5_MOUSE
NC score	0.037725 (rank : 129)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	113	Target Neighborhood Hits	1434	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

CJ068_HUMAN
NC score	0.035652 (rank : 130)	θ value	1.38821 (rank : 67)
Query Neighborhood Hits	113	Target Neighborhood Hits	316	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

MD1L1_MOUSE
NC score	0.033851 (rank : 131)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	113	Target Neighborhood Hits	1001	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

REST_HUMAN
NC score	0.032445 (rank : 132)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	113	Target Neighborhood Hits	1605	Shared Neighborhood Hits	42
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

CP250_HUMAN
NC score	0.031747 (rank : 133)	θ value	0.365318 (rank : 55)
Query Neighborhood Hits	113	Target Neighborhood Hits	1805	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CENPE_HUMAN
NC score	0.029452 (rank : 134)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	113	Target Neighborhood Hits	2060	Shared Neighborhood Hits	48
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

IWS1_HUMAN
NC score	0.029080 (rank : 135)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	113	Target Neighborhood Hits	1241	Shared Neighborhood Hits	33
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

REST_MOUSE
NC score	0.027649 (rank : 136)	θ value	1.38821 (rank : 69)
Query Neighborhood Hits	113	Target Neighborhood Hits	1506	Shared Neighborhood Hits	41
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

KIF3A_MOUSE
NC score	0.027052 (rank : 137)	θ value	0.125558 (rank : 50)
Query Neighborhood Hits	113	Target Neighborhood Hits	715	Shared Neighborhood Hits	30
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

CENPF_HUMAN
NC score	0.026130 (rank : 138)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	113	Target Neighborhood Hits	1932	Shared Neighborhood Hits	44
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

MORC3_HUMAN
NC score	0.025003 (rank : 139)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	113	Target Neighborhood Hits	489	Shared Neighborhood Hits	21
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

KIF3A_HUMAN
NC score	0.024503 (rank : 140)	θ value	0.0563607 (rank : 49)
Query Neighborhood Hits	113	Target Neighborhood Hits	704	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

RAD50_HUMAN
NC score	0.024423 (rank : 141)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	113	Target Neighborhood Hits	1317	Shared Neighborhood Hits	39
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

MTMR3_MOUSE
NC score	0.020542 (rank : 142)	θ value	0.0330416 (rank : 48)
Query Neighborhood Hits	113	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K296	Gene names	Mtmr3
Domain Architecture
Description	Myotubularin-related protein 3 (EC 3.1.3.48).

BPA1_MOUSE
NC score	0.019812 (rank : 143)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	113	Target Neighborhood Hits	1477	Shared Neighborhood Hits	40
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MYH11_HUMAN
NC score	0.019643 (rank : 144)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	113	Target Neighborhood Hits	1806	Shared Neighborhood Hits	43
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

EP15_HUMAN
NC score	0.019073 (rank : 145)	θ value	1.06291 (rank : 63)
Query Neighborhood Hits	113	Target Neighborhood Hits	1021	Shared Neighborhood Hits	31
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

BSN_HUMAN
NC score	0.018580 (rank : 146)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	113	Target Neighborhood Hits	1537	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

POK17_HUMAN
NC score	0.018555 (rank : 147)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	113	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	P63136	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Pol protein [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

DMD_MOUSE
NC score	0.018419 (rank : 148)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	113	Target Neighborhood Hits	1111	Shared Neighborhood Hits	34
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

POK6_HUMAN
NC score	0.018316 (rank : 149)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	113	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	P63133	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Pol protein (HERV-K115 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK5_HUMAN
NC score	0.018308 (rank : 150)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	113	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	P63132	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Pol protein (HERV-K113 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

SPRL1_HUMAN
NC score	0.017721 (rank : 151)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	113	Target Neighborhood Hits	231	Shared Neighborhood Hits	18
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

SEC63_HUMAN
NC score	0.016787 (rank : 152)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	113	Target Neighborhood Hits	586	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

POK3_HUMAN
NC score	0.016232 (rank : 153)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	113	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WJR5, O15312	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Pol protein (HERV-K(C19) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

SEC63_MOUSE
NC score	0.016064 (rank : 154)	θ value	0.813845 (rank : 61)
Query Neighborhood Hits	113	Target Neighborhood Hits	601	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

MIER1_HUMAN
NC score	0.012532 (rank : 155)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	113	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N108, Q5T104, Q6AHY8, Q86TB4, Q8N156, Q8N161, Q8NC37, Q8NES4, Q8NES5, Q8NES6, Q8WWG2, Q9HCG2	Gene names	MIER1, KIAA1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1) (hmi-er1) (Early response 1) (Er1).

CS007_HUMAN
NC score	0.012176 (rank : 156)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	113	Target Neighborhood Hits	401	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

NALP5_MOUSE
NC score	0.011861 (rank : 157)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	113	Target Neighborhood Hits	560	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

EP15_MOUSE
NC score	0.011484 (rank : 158)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	113	Target Neighborhood Hits	820	Shared Neighborhood Hits	24
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

KIRR1_MOUSE
NC score	0.011143 (rank : 159)	θ value	0.279714 (rank : 53)
Query Neighborhood Hits	113	Target Neighborhood Hits	403	Shared Neighborhood Hits	4
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

ZN638_HUMAN
NC score	0.010909 (rank : 160)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	113	Target Neighborhood Hits	343	Shared Neighborhood Hits	11
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

ERCC2_HUMAN
NC score	0.010140 (rank : 161)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	113	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P18074, Q8N721	Gene names	ERCC2, XPD, XPDC
Domain Architecture
Description	TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-) (DNA-repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein) (CXPD) (DNA excision repair protein ERCC-2).

MYCB2_HUMAN
NC score	0.009974 (rank : 162)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	113	Target Neighborhood Hits	390	Shared Neighborhood Hits	12
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

TITIN_HUMAN
NC score	0.009855 (rank : 163)	θ value	0.21417 (rank : 52)
Query Neighborhood Hits	113	Target Neighborhood Hits	2923	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZHX1_MOUSE
NC score	0.009764 (rank : 164)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	113	Target Neighborhood Hits	334	Shared Neighborhood Hits	7
SwissProt Accessions	P70121, Q8BQ68, Q8C6T4, Q8CJG3	Gene names	Zhx1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

KIRR1_HUMAN
NC score	0.009363 (rank : 165)	θ value	1.38821 (rank : 68)
Query Neighborhood Hits	113	Target Neighborhood Hits	401	Shared Neighborhood Hits	4
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

ZHX1_HUMAN
NC score	0.009086 (rank : 166)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	113	Target Neighborhood Hits	307	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKY1, Q8IWD8	Gene names	ZHX1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

MKS1_MOUSE
NC score	0.008666 (rank : 167)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	113	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SW45, Q3V3W3	Gene names	Mks1
Domain Architecture	No domain graphic available
Description	Meckel syndrome type 1 protein homolog.

CS007_MOUSE
NC score	0.008604 (rank : 168)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	113	Target Neighborhood Hits	464	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

PF21B_HUMAN
NC score	0.008503 (rank : 169)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	113	Target Neighborhood Hits	197	Shared Neighborhood Hits	6
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

ZNFX1_HUMAN
NC score	0.007931 (rank : 170)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	113	Target Neighborhood Hits	308	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

LAMC1_HUMAN
NC score	0.006876 (rank : 171)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	113	Target Neighborhood Hits	922	Shared Neighborhood Hits	27
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

TSH3_MOUSE
NC score	0.006307 (rank : 172)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	113	Target Neighborhood Hits	590	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

ZNFX1_MOUSE
NC score	0.006257 (rank : 173)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	113	Target Neighborhood Hits	407	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

RAE2_MOUSE
NC score	0.004457 (rank : 174)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	113	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZD5, Q8CH16	Gene names	Chml, Rep2
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 2 (Rab escort protein 2) (REP-2) (Choroideraemia-like protein).

NELFA_MOUSE
NC score	0.004287 (rank : 175)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	113	Target Neighborhood Hits	195	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

RTN1_MOUSE
NC score	0.004211 (rank : 176)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	113	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

ACHA4_HUMAN
NC score	0.003953 (rank : 177)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	113	Target Neighborhood Hits	131	Shared Neighborhood Hits	2
SwissProt Accessions	P43681, Q4JGR7	Gene names	CHRNA4, NACRA4
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-4 precursor.

TSH3_HUMAN
NC score	0.003917 (rank : 178)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	113	Target Neighborhood Hits	564	Shared Neighborhood Hits	7
SwissProt Accessions	Q63HK5, Q9H0G6, Q9P254	Gene names	TSHZ3, KIAA1474, TSH3, ZNF537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

ETV3_HUMAN
NC score	0.002855 (rank : 179)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	113	Target Neighborhood Hits	312	Shared Neighborhood Hits	5
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

ANR38_HUMAN
NC score	0.002425 (rank : 180)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	113	Target Neighborhood Hits	443	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR35_HUMAN
NC score	0.000730 (rank : 181)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	113	Target Neighborhood Hits	784	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ANK1_MOUSE
NC score	-0.001600 (rank : 182)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	113	Target Neighborhood Hits	430	Shared Neighborhood Hits	6
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

M3K12_HUMAN
NC score	-0.001921 (rank : 183)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	113	Target Neighborhood Hits	940	Shared Neighborhood Hits	9
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

NEK1_MOUSE
NC score	-0.001934 (rank : 184)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	113	Target Neighborhood Hits	1311	Shared Neighborhood Hits	24
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

IKKB_HUMAN
NC score	-0.002961 (rank : 185)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	113	Target Neighborhood Hits	980	Shared Neighborhood Hits	15
SwissProt Accessions	O14920, O75327	Gene names	IKBKB, IKKB
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

NRK_HUMAN
NC score	-0.003152 (rank : 186)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	113	Target Neighborhood Hits	931	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

M3K12_MOUSE
NC score	-0.003548 (rank : 187)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	113	Target Neighborhood Hits	957	Shared Neighborhood Hits	8
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

ZN560_HUMAN
NC score	-0.005281 (rank : 188)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	113	Target Neighborhood Hits	751	Shared Neighborhood Hits	5
SwissProt Accessions	Q96MR9, Q495S9, Q495T1	Gene names	ZNF560
Domain Architecture	No domain graphic available
Description	Zinc finger protein 560.