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Network neighborhood for query Sequence : FRMD1_HUMAN

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FRMD1_HUMAN
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FRMD1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

FRMD6_HUMAN
θ value	9.69798e-87 (rank : 2)	NC score	0.939664 (rank : 3)
Query Neighborhood Hits	48	Target Neighborhood Hits	60	Shared Neighborhood Hits	41
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

FRMD6_MOUSE
θ value	5.32145e-85 (rank : 3)	NC score	0.940946 (rank : 2)
Query Neighborhood Hits	48	Target Neighborhood Hits	63	Shared Neighborhood Hits	41
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

PTN13_HUMAN
θ value	4.14116e-29 (rank : 4)	NC score	0.469793 (rank : 42)
Query Neighborhood Hits	48	Target Neighborhood Hits	471	Shared Neighborhood Hits	43
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
θ value	9.2256e-29 (rank : 5)	NC score	0.476552 (rank : 40)
Query Neighborhood Hits	48	Target Neighborhood Hits	426	Shared Neighborhood Hits	43
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

EZRI_HUMAN
θ value	3.76295e-14 (rank : 6)	NC score	0.632364 (rank : 18)
Query Neighborhood Hits	48	Target Neighborhood Hits	663	Shared Neighborhood Hits	44
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

RADI_HUMAN
θ value	4.91457e-14 (rank : 7)	NC score	0.617078 (rank : 26)
Query Neighborhood Hits	48	Target Neighborhood Hits	741	Shared Neighborhood Hits	44
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	4.91457e-14 (rank : 8)	NC score	0.613940 (rank : 27)
Query Neighborhood Hits	48	Target Neighborhood Hits	773	Shared Neighborhood Hits	44
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

EZRI_MOUSE
θ value	1.42992e-13 (rank : 9)	NC score	0.627414 (rank : 20)
Query Neighborhood Hits	48	Target Neighborhood Hits	693	Shared Neighborhood Hits	44
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

MOES_MOUSE
θ value	1.42992e-13 (rank : 10)	NC score	0.572649 (rank : 32)
Query Neighborhood Hits	48	Target Neighborhood Hits	923	Shared Neighborhood Hits	44
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_HUMAN
θ value	1.86753e-13 (rank : 11)	NC score	0.579038 (rank : 31)
Query Neighborhood Hits	48	Target Neighborhood Hits	892	Shared Neighborhood Hits	44
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

PTN14_MOUSE
θ value	1.133e-10 (rank : 12)	NC score	0.493501 (rank : 34)
Query Neighborhood Hits	48	Target Neighborhood Hits	142	Shared Neighborhood Hits	43
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN14_HUMAN
θ value	7.34386e-10 (rank : 13)	NC score	0.486838 (rank : 37)
Query Neighborhood Hits	48	Target Neighborhood Hits	163	Shared Neighborhood Hits	43
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

MERL_HUMAN
θ value	9.59137e-10 (rank : 14)	NC score	0.651071 (rank : 9)
Query Neighborhood Hits	48	Target Neighborhood Hits	532	Shared Neighborhood Hits	44
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	9.59137e-10 (rank : 15)	NC score	0.651695 (rank : 8)
Query Neighborhood Hits	48	Target Neighborhood Hits	524	Shared Neighborhood Hits	44
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

PTN3_HUMAN
θ value	1.63604e-09 (rank : 16)	NC score	0.481699 (rank : 38)
Query Neighborhood Hits	48	Target Neighborhood Hits	258	Shared Neighborhood Hits	43
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN21_HUMAN
θ value	6.21693e-09 (rank : 17)	NC score	0.491082 (rank : 35)
Query Neighborhood Hits	48	Target Neighborhood Hits	143	Shared Neighborhood Hits	43
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN21_MOUSE
θ value	6.21693e-09 (rank : 18)	NC score	0.490472 (rank : 36)
Query Neighborhood Hits	48	Target Neighborhood Hits	155	Shared Neighborhood Hits	43
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN4_HUMAN
θ value	6.21693e-09 (rank : 19)	NC score	0.481335 (rank : 39)
Query Neighborhood Hits	48	Target Neighborhood Hits	303	Shared Neighborhood Hits	43
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

E41L1_HUMAN
θ value	1.06045e-08 (rank : 20)	NC score	0.641709 (rank : 11)
Query Neighborhood Hits	48	Target Neighborhood Hits	180	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41LA_MOUSE
θ value	4.0297e-08 (rank : 21)	NC score	0.676136 (rank : 4)
Query Neighborhood Hits	48	Target Neighborhood Hits	85	Shared Neighborhood Hits	43
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

MYLIP_HUMAN
θ value	1.17247e-07 (rank : 22)	NC score	0.595463 (rank : 30)
Query Neighborhood Hits	48	Target Neighborhood Hits	162	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

E41LA_HUMAN
θ value	1.53129e-07 (rank : 23)	NC score	0.674434 (rank : 5)
Query Neighborhood Hits	48	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41L1_MOUSE
θ value	2.61198e-07 (rank : 24)	NC score	0.642289 (rank : 10)
Query Neighborhood Hits	48	Target Neighborhood Hits	106	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

MYLIP_MOUSE
θ value	3.41135e-07 (rank : 25)	NC score	0.605742 (rank : 28)
Query Neighborhood Hits	48	Target Neighborhood Hits	139	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

E41L3_HUMAN
θ value	4.45536e-07 (rank : 26)	NC score	0.638788 (rank : 16)
Query Neighborhood Hits	48	Target Neighborhood Hits	113	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41L3_MOUSE
θ value	7.59969e-07 (rank : 27)	NC score	0.627078 (rank : 21)
Query Neighborhood Hits	48	Target Neighborhood Hits	250	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

41_HUMAN
θ value	9.92553e-07 (rank : 28)	NC score	0.640262 (rank : 13)
Query Neighborhood Hits	48	Target Neighborhood Hits	157	Shared Neighborhood Hits	43
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

E41L2_HUMAN
θ value	9.92553e-07 (rank : 29)	NC score	0.620697 (rank : 23)
Query Neighborhood Hits	48	Target Neighborhood Hits	287	Shared Neighborhood Hits	44
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

FRM4B_MOUSE
θ value	1.69304e-06 (rank : 30)	NC score	0.640146 (rank : 14)
Query Neighborhood Hits	48	Target Neighborhood Hits	109	Shared Neighborhood Hits	43
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRMD5_HUMAN
θ value	1.69304e-06 (rank : 31)	NC score	0.665435 (rank : 6)
Query Neighborhood Hits	48	Target Neighborhood Hits	55	Shared Neighborhood Hits	43
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRM4B_HUMAN
θ value	4.92598e-06 (rank : 32)	NC score	0.640064 (rank : 15)
Query Neighborhood Hits	48	Target Neighborhood Hits	117	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRMD5_MOUSE
θ value	4.92598e-06 (rank : 33)	NC score	0.661690 (rank : 7)
Query Neighborhood Hits	48	Target Neighborhood Hits	55	Shared Neighborhood Hits	43
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41L5_HUMAN
θ value	6.43352e-06 (rank : 34)	NC score	0.640499 (rank : 12)
Query Neighborhood Hits	48	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41L2_MOUSE
θ value	5.44631e-05 (rank : 35)	NC score	0.599154 (rank : 29)
Query Neighborhood Hits	48	Target Neighborhood Hits	459	Shared Neighborhood Hits	43
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

FARP1_HUMAN
θ value	5.44631e-05 (rank : 36)	NC score	0.506148 (rank : 33)
Query Neighborhood Hits	48	Target Neighborhood Hits	241	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

41_MOUSE
θ value	0.000121331 (rank : 37)	NC score	0.628810 (rank : 19)
Query Neighborhood Hits	48	Target Neighborhood Hits	184	Shared Neighborhood Hits	43
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

E41LB_MOUSE
θ value	0.00020696 (rank : 38)	NC score	0.636396 (rank : 17)
Query Neighborhood Hits	48	Target Neighborhood Hits	59	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

E41LB_HUMAN
θ value	0.00035302 (rank : 39)	NC score	0.626275 (rank : 22)
Query Neighborhood Hits	48	Target Neighborhood Hits	79	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

FRM4A_HUMAN
θ value	0.00175202 (rank : 40)	NC score	0.617569 (rank : 25)
Query Neighborhood Hits	48	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_MOUSE
θ value	0.00228821 (rank : 41)	NC score	0.617913 (rank : 24)
Query Neighborhood Hits	48	Target Neighborhood Hits	108	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

ABL1_MOUSE
θ value	2.36792 (rank : 42)	NC score	-0.001795 (rank : 123)
Query Neighborhood Hits	48	Target Neighborhood Hits	1178	Shared Neighborhood Hits	3
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

IFIT2_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.012837 (rank : 122)
Query Neighborhood Hits	48	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q64112, Q62385	Gene names	Ifit2, Garg39, Ifi54
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (Interferon-induced 54 kDa protein) (IFI-54K) (Glucocorticoid- attenuated response gene 39 protein) (GARG-39).

CF117_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.025723 (rank : 121)
Query Neighborhood Hits	48	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q96G30, Q8IXM9, Q8N2D1	Gene names	C6orf117
Domain Architecture	No domain graphic available
Description	Protein C6orf117.

TLN2_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.269942 (rank : 45)
Query Neighborhood Hits	48	Target Neighborhood Hits	157	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

OPTN_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.035504 (rank : 120)
Query Neighborhood Hits	48	Target Neighborhood Hits	1120	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

TLN2_MOUSE
θ value	8.99809 (rank : 47)	NC score	0.274050 (rank : 44)
Query Neighborhood Hits	48	Target Neighborhood Hits	149	Shared Neighborhood Hits	44
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

VGFR3_HUMAN
θ value	8.99809 (rank : 48)	NC score	-0.002229 (rank : 124)
Query Neighborhood Hits	48	Target Neighborhood Hits	1037	Shared Neighborhood Hits	3
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

CA106_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.065877 (rank : 103)
Query Neighborhood Hits	48	Target Neighborhood Hits	124	Shared Neighborhood Hits	4
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
θ value	θ > 10 (rank : 50)	NC score	0.065098 (rank : 104)
Query Neighborhood Hits	48	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

CCD50_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.051960 (rank : 113)
Query Neighborhood Hits	48	Target Neighborhood Hits	237	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CD45_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.111729 (rank : 82)
Query Neighborhood Hits	48	Target Neighborhood Hits	243	Shared Neighborhood Hits	8
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD45_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.114699 (rank : 77)
Query Neighborhood Hits	48	Target Neighborhood Hits	178	Shared Neighborhood Hits	10
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

FARP2_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.472429 (rank : 41)
Query Neighborhood Hits	48	Target Neighborhood Hits	240	Shared Neighborhood Hits	42
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.469025 (rank : 43)
Query Neighborhood Hits	48	Target Neighborhood Hits	209	Shared Neighborhood Hits	42
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

IL16_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.051337 (rank : 116)
Query Neighborhood Hits	48	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

IL16_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.054642 (rank : 111)
Query Neighborhood Hits	48	Target Neighborhood Hits	189	Shared Neighborhood Hits	4
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

KRIT1_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.086610 (rank : 97)
Query Neighborhood Hits	48	Target Neighborhood Hits	258	Shared Neighborhood Hits	16
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

KRIT1_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.081561 (rank : 98)
Query Neighborhood Hits	48	Target Neighborhood Hits	258	Shared Neighborhood Hits	18
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

LIN7C_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.050527 (rank : 118)
Query Neighborhood Hits	48	Target Neighborhood Hits	198	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.050527 (rank : 119)
Query Neighborhood Hits	48	Target Neighborhood Hits	198	Shared Neighborhood Hits	4
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

MPDZ_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.051395 (rank : 115)
Query Neighborhood Hits	48	Target Neighborhood Hits	298	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

NEB1_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.051099 (rank : 117)
Query Neighborhood Hits	48	Target Neighborhood Hits	829	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NEB2_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.062415 (rank : 105)
Query Neighborhood Hits	48	Target Neighborhood Hits	883	Shared Neighborhood Hits	11
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.059547 (rank : 107)
Query Neighborhood Hits	48	Target Neighborhood Hits	889	Shared Neighborhood Hits	11
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PAR3L_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.052549 (rank : 112)
Query Neighborhood Hits	48	Target Neighborhood Hits	297	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PARD3_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.051456 (rank : 114)
Query Neighborhood Hits	48	Target Neighborhood Hits	312	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PDZ11_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.055187 (rank : 110)
Query Neighborhood Hits	48	Target Neighborhood Hits	160	Shared Neighborhood Hits	4
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.057418 (rank : 108)
Query Neighborhood Hits	48	Target Neighborhood Hits	154	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PTN11_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.117785 (rank : 71)
Query Neighborhood Hits	48	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.117782 (rank : 72)
Query Neighborhood Hits	48	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN12_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.123887 (rank : 61)
Query Neighborhood Hits	48	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.123545 (rank : 62)
Query Neighborhood Hits	48	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN18_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.132631 (rank : 51)
Query Neighborhood Hits	48	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.128452 (rank : 53)
Query Neighborhood Hits	48	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN1_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.132478 (rank : 52)
Query Neighborhood Hits	48	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.132914 (rank : 49)
Query Neighborhood Hits	48	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN22_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.124332 (rank : 58)
Query Neighborhood Hits	48	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN22_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.123098 (rank : 63)
Query Neighborhood Hits	48	Target Neighborhood Hits	179	Shared Neighborhood Hits	8
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN23_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.114512 (rank : 79)
Query Neighborhood Hits	48	Target Neighborhood Hits	646	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.112616 (rank : 81)
Query Neighborhood Hits	48	Target Neighborhood Hits	726	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN2_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.132757 (rank : 50)
Query Neighborhood Hits	48	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN2_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.134270 (rank : 48)
Query Neighborhood Hits	48	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN5_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.116504 (rank : 73)
Query Neighborhood Hits	48	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.116092 (rank : 74)
Query Neighborhood Hits	48	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN6_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.124215 (rank : 59)
Query Neighborhood Hits	48	Target Neighborhood Hits	234	Shared Neighborhood Hits	9
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.124385 (rank : 57)
Query Neighborhood Hits	48	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN7_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.124085 (rank : 60)
Query Neighborhood Hits	48	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.125340 (rank : 56)
Query Neighborhood Hits	48	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN9_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.126512 (rank : 54)
Query Neighborhood Hits	48	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.126109 (rank : 55)
Query Neighborhood Hits	48	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPR2_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.118872 (rank : 70)
Query Neighborhood Hits	48	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.119324 (rank : 67)
Query Neighborhood Hits	48	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRA_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.107434 (rank : 85)
Query Neighborhood Hits	48	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.106234 (rank : 86)
Query Neighborhood Hits	48	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRB_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.114052 (rank : 80)
Query Neighborhood Hits	48	Target Neighborhood Hits	242	Shared Neighborhood Hits	8
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRD_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.075737 (rank : 100)
Query Neighborhood Hits	48	Target Neighborhood Hits	485	Shared Neighborhood Hits	10
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.073136 (rank : 102)
Query Neighborhood Hits	48	Target Neighborhood Hits	491	Shared Neighborhood Hits	10
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRE_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.108152 (rank : 83)
Query Neighborhood Hits	48	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.107759 (rank : 84)
Query Neighborhood Hits	48	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRF_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.074536 (rank : 101)
Query Neighborhood Hits	48	Target Neighborhood Hits	489	Shared Neighborhood Hits	9
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRG_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.094869 (rank : 90)
Query Neighborhood Hits	48	Target Neighborhood Hits	231	Shared Neighborhood Hits	8
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.094541 (rank : 92)
Query Neighborhood Hits	48	Target Neighborhood Hits	260	Shared Neighborhood Hits	9
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRJ_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.115565 (rank : 76)
Query Neighborhood Hits	48	Target Neighborhood Hits	207	Shared Neighborhood Hits	8
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRJ_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.116050 (rank : 75)
Query Neighborhood Hits	48	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRK_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.097200 (rank : 88)
Query Neighborhood Hits	48	Target Neighborhood Hits	228	Shared Neighborhood Hits	8
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.098122 (rank : 87)
Query Neighborhood Hits	48	Target Neighborhood Hits	223	Shared Neighborhood Hits	8
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRM_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.091839 (rank : 95)
Query Neighborhood Hits	48	Target Neighborhood Hits	244	Shared Neighborhood Hits	8
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.092175 (rank : 94)
Query Neighborhood Hits	48	Target Neighborhood Hits	238	Shared Neighborhood Hits	8
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRN_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.120201 (rank : 65)
Query Neighborhood Hits	48	Target Neighborhood Hits	156	Shared Neighborhood Hits	9
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.119801 (rank : 66)
Query Neighborhood Hits	48	Target Neighborhood Hits	240	Shared Neighborhood Hits	8
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRO_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.120870 (rank : 64)
Query Neighborhood Hits	48	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRR_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.119130 (rank : 68)
Query Neighborhood Hits	48	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.118948 (rank : 69)
Query Neighborhood Hits	48	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRS_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.077290 (rank : 99)
Query Neighborhood Hits	48	Target Neighborhood Hits	472	Shared Neighborhood Hits	9
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRT_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.094547 (rank : 91)
Query Neighborhood Hits	48	Target Neighborhood Hits	217	Shared Neighborhood Hits	8
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.094497 (rank : 93)
Query Neighborhood Hits	48	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRU_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.091244 (rank : 96)
Query Neighborhood Hits	48	Target Neighborhood Hits	237	Shared Neighborhood Hits	8
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRV_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.114564 (rank : 78)
Query Neighborhood Hits	48	Target Neighborhood Hits	179	Shared Neighborhood Hits	8
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRZ_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.095703 (rank : 89)
Query Neighborhood Hits	48	Target Neighborhood Hits	255	Shared Neighborhood Hits	8
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

STXB4_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.062200 (rank : 106)
Query Neighborhood Hits	48	Target Neighborhood Hits	616	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

SYJ2B_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.056253 (rank : 109)
Query Neighborhood Hits	48	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

TLN1_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.250315 (rank : 46)
Query Neighborhood Hits	48	Target Neighborhood Hits	218	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.249218 (rank : 47)
Query Neighborhood Hits	48	Target Neighborhood Hits	213	Shared Neighborhood Hits	40
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

Hits sorted by NC score

FRMD1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	48
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

FRMD6_MOUSE
NC score	0.940946 (rank : 2)	θ value	5.32145e-85 (rank : 3)
Query Neighborhood Hits	48	Target Neighborhood Hits	63	Shared Neighborhood Hits	41
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRMD6_HUMAN
NC score	0.939664 (rank : 3)	θ value	9.69798e-87 (rank : 2)
Query Neighborhood Hits	48	Target Neighborhood Hits	60	Shared Neighborhood Hits	41
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

E41LA_MOUSE
NC score	0.676136 (rank : 4)	θ value	4.0297e-08 (rank : 21)
Query Neighborhood Hits	48	Target Neighborhood Hits	85	Shared Neighborhood Hits	43
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_HUMAN
NC score	0.674434 (rank : 5)	θ value	1.53129e-07 (rank : 23)
Query Neighborhood Hits	48	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

FRMD5_HUMAN
NC score	0.665435 (rank : 6)	θ value	1.69304e-06 (rank : 31)
Query Neighborhood Hits	48	Target Neighborhood Hits	55	Shared Neighborhood Hits	43
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_MOUSE
NC score	0.661690 (rank : 7)	θ value	4.92598e-06 (rank : 33)
Query Neighborhood Hits	48	Target Neighborhood Hits	55	Shared Neighborhood Hits	43
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

MERL_MOUSE
NC score	0.651695 (rank : 8)	θ value	9.59137e-10 (rank : 15)
Query Neighborhood Hits	48	Target Neighborhood Hits	524	Shared Neighborhood Hits	44
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MERL_HUMAN
NC score	0.651071 (rank : 9)	θ value	9.59137e-10 (rank : 14)
Query Neighborhood Hits	48	Target Neighborhood Hits	532	Shared Neighborhood Hits	44
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

E41L1_MOUSE
NC score	0.642289 (rank : 10)	θ value	2.61198e-07 (rank : 24)
Query Neighborhood Hits	48	Target Neighborhood Hits	106	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_HUMAN
NC score	0.641709 (rank : 11)	θ value	1.06045e-08 (rank : 20)
Query Neighborhood Hits	48	Target Neighborhood Hits	180	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L5_HUMAN
NC score	0.640499 (rank : 12)	θ value	6.43352e-06 (rank : 34)
Query Neighborhood Hits	48	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

41_HUMAN
NC score	0.640262 (rank : 13)	θ value	9.92553e-07 (rank : 28)
Query Neighborhood Hits	48	Target Neighborhood Hits	157	Shared Neighborhood Hits	43
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

FRM4B_MOUSE
NC score	0.640146 (rank : 14)	θ value	1.69304e-06 (rank : 30)
Query Neighborhood Hits	48	Target Neighborhood Hits	109	Shared Neighborhood Hits	43
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4B_HUMAN
NC score	0.640064 (rank : 15)	θ value	4.92598e-06 (rank : 32)
Query Neighborhood Hits	48	Target Neighborhood Hits	117	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

E41L3_HUMAN
NC score	0.638788 (rank : 16)	θ value	4.45536e-07 (rank : 26)
Query Neighborhood Hits	48	Target Neighborhood Hits	113	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41LB_MOUSE
NC score	0.636396 (rank : 17)	θ value	0.00020696 (rank : 38)
Query Neighborhood Hits	48	Target Neighborhood Hits	59	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

EZRI_HUMAN
NC score	0.632364 (rank : 18)	θ value	3.76295e-14 (rank : 6)
Query Neighborhood Hits	48	Target Neighborhood Hits	663	Shared Neighborhood Hits	44
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

41_MOUSE
NC score	0.628810 (rank : 19)	θ value	0.000121331 (rank : 37)
Query Neighborhood Hits	48	Target Neighborhood Hits	184	Shared Neighborhood Hits	43
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

EZRI_MOUSE
NC score	0.627414 (rank : 20)	θ value	1.42992e-13 (rank : 9)
Query Neighborhood Hits	48	Target Neighborhood Hits	693	Shared Neighborhood Hits	44
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

E41L3_MOUSE
NC score	0.627078 (rank : 21)	θ value	7.59969e-07 (rank : 27)
Query Neighborhood Hits	48	Target Neighborhood Hits	250	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41LB_HUMAN
NC score	0.626275 (rank : 22)	θ value	0.00035302 (rank : 39)
Query Neighborhood Hits	48	Target Neighborhood Hits	79	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

E41L2_HUMAN
NC score	0.620697 (rank : 23)	θ value	9.92553e-07 (rank : 29)
Query Neighborhood Hits	48	Target Neighborhood Hits	287	Shared Neighborhood Hits	44
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

FRM4A_MOUSE
NC score	0.617913 (rank : 24)	θ value	0.00228821 (rank : 41)
Query Neighborhood Hits	48	Target Neighborhood Hits	108	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_HUMAN
NC score	0.617569 (rank : 25)	θ value	0.00175202 (rank : 40)
Query Neighborhood Hits	48	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

RADI_HUMAN
NC score	0.617078 (rank : 26)	θ value	4.91457e-14 (rank : 7)
Query Neighborhood Hits	48	Target Neighborhood Hits	741	Shared Neighborhood Hits	44
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
NC score	0.613940 (rank : 27)	θ value	4.91457e-14 (rank : 8)
Query Neighborhood Hits	48	Target Neighborhood Hits	773	Shared Neighborhood Hits	44
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

MYLIP_MOUSE
NC score	0.605742 (rank : 28)	θ value	3.41135e-07 (rank : 25)
Query Neighborhood Hits	48	Target Neighborhood Hits	139	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

E41L2_MOUSE
NC score	0.599154 (rank : 29)	θ value	5.44631e-05 (rank : 35)
Query Neighborhood Hits	48	Target Neighborhood Hits	459	Shared Neighborhood Hits	43
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MYLIP_HUMAN
NC score	0.595463 (rank : 30)	θ value	1.17247e-07 (rank : 22)
Query Neighborhood Hits	48	Target Neighborhood Hits	162	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MOES_HUMAN
NC score	0.579038 (rank : 31)	θ value	1.86753e-13 (rank : 11)
Query Neighborhood Hits	48	Target Neighborhood Hits	892	Shared Neighborhood Hits	44
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_MOUSE
NC score	0.572649 (rank : 32)	θ value	1.42992e-13 (rank : 10)
Query Neighborhood Hits	48	Target Neighborhood Hits	923	Shared Neighborhood Hits	44
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

FARP1_HUMAN
NC score	0.506148 (rank : 33)	θ value	5.44631e-05 (rank : 36)
Query Neighborhood Hits	48	Target Neighborhood Hits	241	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

PTN14_MOUSE
NC score	0.493501 (rank : 34)	θ value	1.133e-10 (rank : 12)
Query Neighborhood Hits	48	Target Neighborhood Hits	142	Shared Neighborhood Hits	43
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN21_HUMAN
NC score	0.491082 (rank : 35)	θ value	6.21693e-09 (rank : 17)
Query Neighborhood Hits	48	Target Neighborhood Hits	143	Shared Neighborhood Hits	43
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN21_MOUSE
NC score	0.490472 (rank : 36)	θ value	6.21693e-09 (rank : 18)
Query Neighborhood Hits	48	Target Neighborhood Hits	155	Shared Neighborhood Hits	43
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN14_HUMAN
NC score	0.486838 (rank : 37)	θ value	7.34386e-10 (rank : 13)
Query Neighborhood Hits	48	Target Neighborhood Hits	163	Shared Neighborhood Hits	43
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN3_HUMAN
NC score	0.481699 (rank : 38)	θ value	1.63604e-09 (rank : 16)
Query Neighborhood Hits	48	Target Neighborhood Hits	258	Shared Neighborhood Hits	43
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN4_HUMAN
NC score	0.481335 (rank : 39)	θ value	6.21693e-09 (rank : 19)
Query Neighborhood Hits	48	Target Neighborhood Hits	303	Shared Neighborhood Hits	43
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN13_MOUSE
NC score	0.476552 (rank : 40)	θ value	9.2256e-29 (rank : 5)
Query Neighborhood Hits	48	Target Neighborhood Hits	426	Shared Neighborhood Hits	43
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

FARP2_HUMAN
NC score	0.472429 (rank : 41)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	48	Target Neighborhood Hits	240	Shared Neighborhood Hits	42
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

PTN13_HUMAN
NC score	0.469793 (rank : 42)	θ value	4.14116e-29 (rank : 4)
Query Neighborhood Hits	48	Target Neighborhood Hits	471	Shared Neighborhood Hits	43
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

FARP2_MOUSE
NC score	0.469025 (rank : 43)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	48	Target Neighborhood Hits	209	Shared Neighborhood Hits	42
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

TLN2_MOUSE
NC score	0.274050 (rank : 44)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	48	Target Neighborhood Hits	149	Shared Neighborhood Hits	44
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN2_HUMAN
NC score	0.269942 (rank : 45)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	48	Target Neighborhood Hits	157	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN1_HUMAN
NC score	0.250315 (rank : 46)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	48	Target Neighborhood Hits	218	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
NC score	0.249218 (rank : 47)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	48	Target Neighborhood Hits	213	Shared Neighborhood Hits	40
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

PTN2_MOUSE
NC score	0.134270 (rank : 48)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	48	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN1_MOUSE
NC score	0.132914 (rank : 49)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	48	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN2_HUMAN
NC score	0.132757 (rank : 50)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	48	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN18_HUMAN
NC score	0.132631 (rank : 51)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	48	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN1_HUMAN
NC score	0.132478 (rank : 52)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	48	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN18_MOUSE
NC score	0.128452 (rank : 53)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	48	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN9_HUMAN
NC score	0.126512 (rank : 54)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	48	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
NC score	0.126109 (rank : 55)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	48	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN7_MOUSE
NC score	0.125340 (rank : 56)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	48	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN6_MOUSE
NC score	0.124385 (rank : 57)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	48	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN22_HUMAN
NC score	0.124332 (rank : 58)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	48	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN6_HUMAN
NC score	0.124215 (rank : 59)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	48	Target Neighborhood Hits	234	Shared Neighborhood Hits	9
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN7_HUMAN
NC score	0.124085 (rank : 60)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	48	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN12_HUMAN
NC score	0.123887 (rank : 61)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	48	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
NC score	0.123545 (rank : 62)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	48	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN22_MOUSE
NC score	0.123098 (rank : 63)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	48	Target Neighborhood Hits	179	Shared Neighborhood Hits	8
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTPRO_HUMAN
NC score	0.120870 (rank : 64)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	48	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRN_HUMAN
NC score	0.120201 (rank : 65)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	48	Target Neighborhood Hits	156	Shared Neighborhood Hits	9
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
NC score	0.119801 (rank : 66)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	48	Target Neighborhood Hits	240	Shared Neighborhood Hits	8
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPR2_MOUSE
NC score	0.119324 (rank : 67)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	48	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRR_HUMAN
NC score	0.119130 (rank : 68)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	48	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
NC score	0.118948 (rank : 69)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	48	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPR2_HUMAN
NC score	0.118872 (rank : 70)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	48	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTN11_HUMAN
NC score	0.117785 (rank : 71)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	48	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
NC score	0.117782 (rank : 72)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	48	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN5_HUMAN
NC score	0.116504 (rank : 73)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	48	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
NC score	0.116092 (rank : 74)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	48	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTPRJ_MOUSE
NC score	0.116050 (rank : 75)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	48	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRJ_HUMAN
NC score	0.115565 (rank : 76)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	48	Target Neighborhood Hits	207	Shared Neighborhood Hits	8
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

CD45_MOUSE
NC score	0.114699 (rank : 77)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	48	Target Neighborhood Hits	178	Shared Neighborhood Hits	10
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTPRV_MOUSE
NC score	0.114564 (rank : 78)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	48	Target Neighborhood Hits	179	Shared Neighborhood Hits	8
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTN23_HUMAN
NC score	0.114512 (rank : 79)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	48	Target Neighborhood Hits	646	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTPRB_HUMAN
NC score	0.114052 (rank : 80)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	48	Target Neighborhood Hits	242	Shared Neighborhood Hits	8
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTN23_MOUSE
NC score	0.112616 (rank : 81)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	48	Target Neighborhood Hits	726	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

CD45_HUMAN
NC score	0.111729 (rank : 82)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	48	Target Neighborhood Hits	243	Shared Neighborhood Hits	8
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTPRE_HUMAN
NC score	0.108152 (rank : 83)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	48	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
NC score	0.107759 (rank : 84)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	48	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_HUMAN
NC score	0.107434 (rank : 85)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	48	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
NC score	0.106234 (rank : 86)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	48	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRK_MOUSE
NC score	0.098122 (rank : 87)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	48	Target Neighborhood Hits	223	Shared Neighborhood Hits	8
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_HUMAN
NC score	0.097200 (rank : 88)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	48	Target Neighborhood Hits	228	Shared Neighborhood Hits	8
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRZ_HUMAN
NC score	0.095703 (rank : 89)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	48	Target Neighborhood Hits	255	Shared Neighborhood Hits	8
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTPRG_HUMAN
NC score	0.094869 (rank : 90)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	48	Target Neighborhood Hits	231	Shared Neighborhood Hits	8
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRT_HUMAN
NC score	0.094547 (rank : 91)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	48	Target Neighborhood Hits	217	Shared Neighborhood Hits	8
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRG_MOUSE
NC score	0.094541 (rank : 92)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	48	Target Neighborhood Hits	260	Shared Neighborhood Hits	9
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRT_MOUSE
NC score	0.094497 (rank : 93)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	48	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRM_MOUSE
NC score	0.092175 (rank : 94)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	48	Target Neighborhood Hits	238	Shared Neighborhood Hits	8
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_HUMAN
NC score	0.091839 (rank : 95)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	48	Target Neighborhood Hits	244	Shared Neighborhood Hits	8
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRU_HUMAN
NC score	0.091244 (rank : 96)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	48	Target Neighborhood Hits	237	Shared Neighborhood Hits	8
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

KRIT1_HUMAN
NC score	0.086610 (rank : 97)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	48	Target Neighborhood Hits	258	Shared Neighborhood Hits	16
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

KRIT1_MOUSE
NC score	0.081561 (rank : 98)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	48	Target Neighborhood Hits	258	Shared Neighborhood Hits	18
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

PTPRS_HUMAN
NC score	0.077290 (rank : 99)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	48	Target Neighborhood Hits	472	Shared Neighborhood Hits	9
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRD_HUMAN
NC score	0.075737 (rank : 100)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	48	Target Neighborhood Hits	485	Shared Neighborhood Hits	10
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRF_HUMAN
NC score	0.074536 (rank : 101)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	48	Target Neighborhood Hits	489	Shared Neighborhood Hits	9
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRD_MOUSE
NC score	0.073136 (rank : 102)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	48	Target Neighborhood Hits	491	Shared Neighborhood Hits	10
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

CA106_HUMAN
NC score	0.065877 (rank : 103)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	48	Target Neighborhood Hits	124	Shared Neighborhood Hits	4
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
NC score	0.065098 (rank : 104)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	48	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

NEB2_HUMAN
NC score	0.062415 (rank : 105)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	48	Target Neighborhood Hits	883	Shared Neighborhood Hits	11
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

STXB4_HUMAN
NC score	0.062200 (rank : 106)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	48	Target Neighborhood Hits	616	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

NEB2_MOUSE
NC score	0.059547 (rank : 107)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	48	Target Neighborhood Hits	889	Shared Neighborhood Hits	11
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PDZ11_MOUSE
NC score	0.057418 (rank : 108)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	48	Target Neighborhood Hits	154	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

SYJ2B_HUMAN
NC score	0.056253 (rank : 109)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	48	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

PDZ11_HUMAN
NC score	0.055187 (rank : 110)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	48	Target Neighborhood Hits	160	Shared Neighborhood Hits	4
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

IL16_MOUSE
NC score	0.054642 (rank : 111)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	48	Target Neighborhood Hits	189	Shared Neighborhood Hits	4
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PAR3L_HUMAN
NC score	0.052549 (rank : 112)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	48	Target Neighborhood Hits	297	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

CCD50_HUMAN
NC score	0.051960 (rank : 113)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	48	Target Neighborhood Hits	237	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

PARD3_HUMAN
NC score	0.051456 (rank : 114)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	48	Target Neighborhood Hits	312	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

MPDZ_MOUSE
NC score	0.051395 (rank : 115)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	48	Target Neighborhood Hits	298	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

IL16_HUMAN
NC score	0.051337 (rank : 116)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	48	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

NEB1_HUMAN
NC score	0.051099 (rank : 117)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	48	Target Neighborhood Hits	829	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

LIN7C_HUMAN
NC score	0.050527 (rank : 118)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	48	Target Neighborhood Hits	198	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NUP9	Gene names	LIN7C, MALS3, VELI3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

LIN7C_MOUSE
NC score	0.050527 (rank : 119)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	48	Target Neighborhood Hits	198	Shared Neighborhood Hits	4
SwissProt Accessions	O88952	Gene names	Lin7c, Mals3, Veli3
Domain Architecture	No domain graphic available
Description	Lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3 protein).

OPTN_MOUSE
NC score	0.035504 (rank : 120)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	48	Target Neighborhood Hits	1120	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

CF117_HUMAN
NC score	0.025723 (rank : 121)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	48	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q96G30, Q8IXM9, Q8N2D1	Gene names	C6orf117
Domain Architecture	No domain graphic available
Description	Protein C6orf117.

IFIT2_MOUSE
NC score	0.012837 (rank : 122)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	48	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q64112, Q62385	Gene names	Ifit2, Garg39, Ifi54
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (Interferon-induced 54 kDa protein) (IFI-54K) (Glucocorticoid- attenuated response gene 39 protein) (GARG-39).

ABL1_MOUSE
NC score	-0.001795 (rank : 123)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	48	Target Neighborhood Hits	1178	Shared Neighborhood Hits	3
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

VGFR3_HUMAN
NC score	-0.002229 (rank : 124)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	48	Target Neighborhood Hits	1037	Shared Neighborhood Hits	3
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).