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Network neighborhood for query Sequence : FRM4B_MOUSE

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FRM4B_MOUSE
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FRM4A_HUMAN
θ value	0 (rank : 1)	NC score	0.981184 (rank : 4)
Query Neighborhood Hits	109	Target Neighborhood Hits	110	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_MOUSE
θ value	0 (rank : 2)	NC score	0.981828 (rank : 3)
Query Neighborhood Hits	109	Target Neighborhood Hits	108	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4B_HUMAN
θ value	0 (rank : 3)	NC score	0.996374 (rank : 2)
Query Neighborhood Hits	109	Target Neighborhood Hits	117	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4B_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	109
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

RADI_HUMAN
θ value	5.0505e-35 (rank : 5)	NC score	0.720874 (rank : 26)
Query Neighborhood Hits	109	Target Neighborhood Hits	741	Shared Neighborhood Hits	76
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	5.0505e-35 (rank : 6)	NC score	0.717732 (rank : 27)
Query Neighborhood Hits	109	Target Neighborhood Hits	773	Shared Neighborhood Hits	74
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

EZRI_MOUSE
θ value	1.12514e-34 (rank : 7)	NC score	0.732047 (rank : 25)
Query Neighborhood Hits	109	Target Neighborhood Hits	693	Shared Neighborhood Hits	70
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_HUMAN
θ value	3.27365e-34 (rank : 8)	NC score	0.735666 (rank : 24)
Query Neighborhood Hits	109	Target Neighborhood Hits	663	Shared Neighborhood Hits	71
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

MOES_HUMAN
θ value	9.52487e-34 (rank : 9)	NC score	0.678709 (rank : 30)
Query Neighborhood Hits	109	Target Neighborhood Hits	892	Shared Neighborhood Hits	74
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_MOUSE
θ value	4.72714e-33 (rank : 10)	NC score	0.670282 (rank : 31)
Query Neighborhood Hits	109	Target Neighborhood Hits	923	Shared Neighborhood Hits	74
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MERL_HUMAN
θ value	8.3442e-30 (rank : 11)	NC score	0.765439 (rank : 19)
Query Neighborhood Hits	109	Target Neighborhood Hits	532	Shared Neighborhood Hits	66
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	3.17079e-29 (rank : 12)	NC score	0.765181 (rank : 20)
Query Neighborhood Hits	109	Target Neighborhood Hits	524	Shared Neighborhood Hits	66
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

E41L1_HUMAN
θ value	3.07116e-24 (rank : 13)	NC score	0.787868 (rank : 13)
Query Neighborhood Hits	109	Target Neighborhood Hits	180	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_MOUSE
θ value	6.84181e-24 (rank : 14)	NC score	0.791561 (rank : 12)
Query Neighborhood Hits	109	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

PTN21_MOUSE
θ value	1.99067e-23 (rank : 15)	NC score	0.565420 (rank : 36)
Query Neighborhood Hits	109	Target Neighborhood Hits	155	Shared Neighborhood Hits	48
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN14_MOUSE
θ value	2.59989e-23 (rank : 16)	NC score	0.554624 (rank : 39)
Query Neighborhood Hits	109	Target Neighborhood Hits	142	Shared Neighborhood Hits	47
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN21_HUMAN
θ value	3.39556e-23 (rank : 17)	NC score	0.562620 (rank : 38)
Query Neighborhood Hits	109	Target Neighborhood Hits	143	Shared Neighborhood Hits	48
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

FRMD5_HUMAN
θ value	7.56453e-23 (rank : 18)	NC score	0.817464 (rank : 6)
Query Neighborhood Hits	109	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

PTN14_HUMAN
θ value	7.56453e-23 (rank : 19)	NC score	0.548072 (rank : 41)
Query Neighborhood Hits	109	Target Neighborhood Hits	163	Shared Neighborhood Hits	47
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

E41L2_HUMAN
θ value	9.87957e-23 (rank : 20)	NC score	0.772405 (rank : 18)
Query Neighborhood Hits	109	Target Neighborhood Hits	287	Shared Neighborhood Hits	58
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L5_HUMAN
θ value	2.20094e-22 (rank : 21)	NC score	0.809298 (rank : 7)
Query Neighborhood Hits	109	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

FRMD5_MOUSE
θ value	2.20094e-22 (rank : 22)	NC score	0.817589 (rank : 5)
Query Neighborhood Hits	109	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41LB_MOUSE
θ value	1.09232e-21 (rank : 23)	NC score	0.803337 (rank : 10)
Query Neighborhood Hits	109	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

E41L3_HUMAN
θ value	4.15078e-21 (rank : 24)	NC score	0.787501 (rank : 14)
Query Neighborhood Hits	109	Target Neighborhood Hits	113	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41L3_MOUSE
θ value	7.0802e-21 (rank : 25)	NC score	0.774721 (rank : 16)
Query Neighborhood Hits	109	Target Neighborhood Hits	250	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41LA_HUMAN
θ value	9.24701e-21 (rank : 26)	NC score	0.808257 (rank : 8)
Query Neighborhood Hits	109	Target Neighborhood Hits	87	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41L2_MOUSE
θ value	1.2077e-20 (rank : 27)	NC score	0.750178 (rank : 22)
Query Neighborhood Hits	109	Target Neighborhood Hits	459	Shared Neighborhood Hits	54
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41LB_HUMAN
θ value	1.2077e-20 (rank : 28)	NC score	0.794689 (rank : 11)
Query Neighborhood Hits	109	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

PTN3_HUMAN
θ value	1.5773e-20 (rank : 29)	NC score	0.553843 (rank : 40)
Query Neighborhood Hits	109	Target Neighborhood Hits	258	Shared Neighborhood Hits	48
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

CA106_HUMAN
θ value	2.69047e-20 (rank : 30)	NC score	0.438201 (rank : 44)
Query Neighborhood Hits	109	Target Neighborhood Hits	124	Shared Neighborhood Hits	8
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
θ value	4.58923e-20 (rank : 31)	NC score	0.434925 (rank : 45)
Query Neighborhood Hits	109	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

PTN4_HUMAN
θ value	4.58923e-20 (rank : 32)	NC score	0.563483 (rank : 37)
Query Neighborhood Hits	109	Target Neighborhood Hits	303	Shared Neighborhood Hits	48
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

FARP2_HUMAN
θ value	7.82807e-20 (rank : 33)	NC score	0.647414 (rank : 33)
Query Neighborhood Hits	109	Target Neighborhood Hits	240	Shared Neighborhood Hits	48
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

41_HUMAN
θ value	1.02238e-19 (rank : 34)	NC score	0.779284 (rank : 15)
Query Neighborhood Hits	109	Target Neighborhood Hits	157	Shared Neighborhood Hits	52
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

E41LA_MOUSE
θ value	3.88503e-19 (rank : 35)	NC score	0.807418 (rank : 9)
Query Neighborhood Hits	109	Target Neighborhood Hits	85	Shared Neighborhood Hits	49
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

FARP1_HUMAN
θ value	3.88503e-19 (rank : 36)	NC score	0.665356 (rank : 32)
Query Neighborhood Hits	109	Target Neighborhood Hits	241	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

41_MOUSE
θ value	8.65492e-19 (rank : 37)	NC score	0.773500 (rank : 17)
Query Neighborhood Hits	109	Target Neighborhood Hits	184	Shared Neighborhood Hits	52
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

PTN13_HUMAN
θ value	9.56915e-18 (rank : 38)	NC score	0.443676 (rank : 43)
Query Neighborhood Hits	109	Target Neighborhood Hits	471	Shared Neighborhood Hits	52
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

FARP2_MOUSE
θ value	2.13179e-17 (rank : 39)	NC score	0.636075 (rank : 35)
Query Neighborhood Hits	109	Target Neighborhood Hits	209	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

PTN13_MOUSE
θ value	3.63628e-17 (rank : 40)	NC score	0.452163 (rank : 42)
Query Neighborhood Hits	109	Target Neighborhood Hits	426	Shared Neighborhood Hits	50
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

MYLIP_MOUSE
θ value	1.80466e-16 (rank : 41)	NC score	0.763790 (rank : 21)
Query Neighborhood Hits	109	Target Neighborhood Hits	139	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_HUMAN
θ value	5.8054e-15 (rank : 42)	NC score	0.746396 (rank : 23)
Query Neighborhood Hits	109	Target Neighborhood Hits	162	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

FRMD6_HUMAN
θ value	1.09485e-13 (rank : 43)	NC score	0.697860 (rank : 28)
Query Neighborhood Hits	109	Target Neighborhood Hits	60	Shared Neighborhood Hits	44
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

FRMD6_MOUSE
θ value	6.00763e-12 (rank : 44)	NC score	0.692317 (rank : 29)
Query Neighborhood Hits	109	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRMD1_HUMAN
θ value	1.69304e-06 (rank : 45)	NC score	0.640146 (rank : 34)
Query Neighborhood Hits	109	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

MYO10_HUMAN
θ value	0.00020696 (rank : 46)	NC score	0.061777 (rank : 104)
Query Neighborhood Hits	109	Target Neighborhood Hits	920	Shared Neighborhood Hits	46
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

TLN2_MOUSE
θ value	0.000786445 (rank : 47)	NC score	0.360718 (rank : 46)
Query Neighborhood Hits	109	Target Neighborhood Hits	149	Shared Neighborhood Hits	52
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN2_HUMAN
θ value	0.00134147 (rank : 48)	NC score	0.354471 (rank : 48)
Query Neighborhood Hits	109	Target Neighborhood Hits	157	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN1_HUMAN
θ value	0.00665767 (rank : 49)	NC score	0.355767 (rank : 47)
Query Neighborhood Hits	109	Target Neighborhood Hits	218	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	0.00665767 (rank : 50)	NC score	0.353512 (rank : 49)
Query Neighborhood Hits	109	Target Neighborhood Hits	213	Shared Neighborhood Hits	50
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

VDR_HUMAN
θ value	0.125558 (rank : 51)	NC score	0.009108 (rank : 176)
Query Neighborhood Hits	109	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

CENPE_HUMAN
θ value	0.163984 (rank : 52)	NC score	0.043335 (rank : 137)
Query Neighborhood Hits	109	Target Neighborhood Hits	2060	Shared Neighborhood Hits	46
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

PAK7_MOUSE
θ value	0.365318 (rank : 53)	NC score	-0.000512 (rank : 185)
Query Neighborhood Hits	109	Target Neighborhood Hits	875	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C015, Q3TQJ7, Q6RWS7	Gene names	Pak7, Pak5
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5).

THSD1_MOUSE
θ value	0.365318 (rank : 54)	NC score	0.035887 (rank : 150)
Query Neighborhood Hits	109	Target Neighborhood Hits	153	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

CCD46_HUMAN
θ value	0.47712 (rank : 55)	NC score	0.048381 (rank : 134)
Query Neighborhood Hits	109	Target Neighborhood Hits	1430	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

GCC2_HUMAN
θ value	0.47712 (rank : 56)	NC score	0.040737 (rank : 143)
Query Neighborhood Hits	109	Target Neighborhood Hits	1558	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GOGA4_HUMAN
θ value	0.47712 (rank : 57)	NC score	0.051746 (rank : 126)
Query Neighborhood Hits	109	Target Neighborhood Hits	2034	Shared Neighborhood Hits	44
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

PEPL_MOUSE
θ value	0.47712 (rank : 58)	NC score	0.043293 (rank : 138)
Query Neighborhood Hits	109	Target Neighborhood Hits	1105	Shared Neighborhood Hits	37
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

RBP24_HUMAN
θ value	0.47712 (rank : 59)	NC score	0.040799 (rank : 142)
Query Neighborhood Hits	109	Target Neighborhood Hits	1559	Shared Neighborhood Hits	42
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

CCD38_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.035665 (rank : 151)
Query Neighborhood Hits	109	Target Neighborhood Hits	287	Shared Neighborhood Hits	22
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

CF182_MOUSE
θ value	0.62314 (rank : 61)	NC score	0.045770 (rank : 136)
Query Neighborhood Hits	109	Target Neighborhood Hits	551	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

GOGA1_MOUSE
θ value	0.62314 (rank : 62)	NC score	0.039363 (rank : 146)
Query Neighborhood Hits	109	Target Neighborhood Hits	994	Shared Neighborhood Hits	36
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

SMC2_HUMAN
θ value	0.62314 (rank : 63)	NC score	0.046665 (rank : 135)
Query Neighborhood Hits	109	Target Neighborhood Hits	1405	Shared Neighborhood Hits	42
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

KINH_HUMAN
θ value	0.813845 (rank : 64)	NC score	0.031584 (rank : 157)
Query Neighborhood Hits	109	Target Neighborhood Hits	1231	Shared Neighborhood Hits	34
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

KINH_MOUSE
θ value	1.06291 (rank : 65)	NC score	0.029763 (rank : 158)
Query Neighborhood Hits	109	Target Neighborhood Hits	1082	Shared Neighborhood Hits	34
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

DNJC3_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.012901 (rank : 172)
Query Neighborhood Hits	109	Target Neighborhood Hits	223	Shared Neighborhood Hits	7
SwissProt Accessions	Q13217, Q86WT9, Q8N4N2	Gene names	DNAJC3, P58IPK, PRKRI
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

MCES_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.033751 (rank : 154)
Query Neighborhood Hits	109	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	O43148, O94996, Q9UIJ9	Gene names	RNMT, KIAA0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase) (hcm1p) (hCMT1) (hMet).

WNK2_HUMAN
θ value	1.81305 (rank : 68)	NC score	0.001329 (rank : 184)
Query Neighborhood Hits	109	Target Neighborhood Hits	1407	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

CCD45_MOUSE
θ value	2.36792 (rank : 69)	NC score	0.050661 (rank : 130)
Query Neighborhood Hits	109	Target Neighborhood Hits	663	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

FYCO1_HUMAN
θ value	2.36792 (rank : 70)	NC score	0.034071 (rank : 153)
Query Neighborhood Hits	109	Target Neighborhood Hits	1149	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

REXO4_MOUSE
θ value	2.36792 (rank : 71)	NC score	0.014437 (rank : 168)
Query Neighborhood Hits	109	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PAQ4, Q3UU17, Q8C524	Gene names	Rexo4, Gm111, Pmc2, Xpmc2h
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein homolog).

TGON2_HUMAN
θ value	2.36792 (rank : 72)	NC score	0.011459 (rank : 174)
Query Neighborhood Hits	109	Target Neighborhood Hits	1037	Shared Neighborhood Hits	20
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TRPM6_MOUSE
θ value	2.36792 (rank : 73)	NC score	0.014005 (rank : 169)
Query Neighborhood Hits	109	Target Neighborhood Hits	78	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

VGLL2_MOUSE
θ value	2.36792 (rank : 74)	NC score	0.017577 (rank : 166)
Query Neighborhood Hits	109	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGW8, Q8BWB4	Gene names	Vgll2, Vgl2, Vito1
Domain Architecture	No domain graphic available
Description	Transcription cofactor vestigial-like protein 2 (Vgl-2) (Protein VITO1).

ZO1_HUMAN
θ value	2.36792 (rank : 75)	NC score	0.023395 (rank : 162)
Query Neighborhood Hits	109	Target Neighborhood Hits	474	Shared Neighborhood Hits	8
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

GPTC8_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.020251 (rank : 164)
Query Neighborhood Hits	109	Target Neighborhood Hits	366	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

PESC_MOUSE
θ value	3.0926 (rank : 77)	NC score	0.036754 (rank : 148)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EQ61, Q542F0	Gene names	Pes1
Domain Architecture
Description	Pescadillo homolog 1.

THAP6_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.029696 (rank : 159)
Query Neighborhood Hits	109	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TBB0	Gene names	THAP6
Domain Architecture
Description	THAP domain-containing protein 6.

ZN519_HUMAN
θ value	3.0926 (rank : 79)	NC score	-0.005018 (rank : 189)
Query Neighborhood Hits	109	Target Neighborhood Hits	738	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TB69	Gene names	ZNF519
Domain Architecture
Description	Zinc finger protein 519.

ATS5_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.005492 (rank : 181)
Query Neighborhood Hits	109	Target Neighborhood Hits	141	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

CHD9_MOUSE
θ value	4.03905 (rank : 81)	NC score	0.011022 (rank : 175)
Query Neighborhood Hits	109	Target Neighborhood Hits	427	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

DCC_HUMAN
θ value	4.03905 (rank : 82)	NC score	-0.000651 (rank : 186)
Query Neighborhood Hits	109	Target Neighborhood Hits	583	Shared Neighborhood Hits	4
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

FILA_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.013131 (rank : 171)
Query Neighborhood Hits	109	Target Neighborhood Hits	685	Shared Neighborhood Hits	20
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

LUZP1_MOUSE
θ value	4.03905 (rank : 84)	NC score	0.021436 (rank : 163)
Query Neighborhood Hits	109	Target Neighborhood Hits	940	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MYO5C_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.033143 (rank : 155)
Query Neighborhood Hits	109	Target Neighborhood Hits	1206	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

PAK7_HUMAN
θ value	4.03905 (rank : 86)	NC score	-0.001790 (rank : 187)
Query Neighborhood Hits	109	Target Neighborhood Hits	875	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P286, Q5W115, Q9BX09, Q9ULF6	Gene names	PAK7, KIAA1264, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (PAK-5).

PEPL_HUMAN
θ value	4.03905 (rank : 87)	NC score	0.039553 (rank : 145)
Query Neighborhood Hits	109	Target Neighborhood Hits	1141	Shared Neighborhood Hits	36
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

SPG21_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.026561 (rank : 160)
Query Neighborhood Hits	109	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZD8, Q6ZMB6	Gene names	SPG21, ACP33
Domain Architecture	No domain graphic available
Description	Maspardin (Spastic paraplegia 21 autosomal recessive Mast syndrome protein) (Acid cluster protein 33).

CP135_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.042886 (rank : 139)
Query Neighborhood Hits	109	Target Neighborhood Hits	1278	Shared Neighborhood Hits	39
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DPOLZ_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.013921 (rank : 170)
Query Neighborhood Hits	109	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

IFT74_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.034620 (rank : 152)
Query Neighborhood Hits	109	Target Neighborhood Hits	939	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

PKHA6_MOUSE
θ value	5.27518 (rank : 92)	NC score	0.049982 (rank : 133)
Query Neighborhood Hits	109	Target Neighborhood Hits	591	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

ROCK2_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.016098 (rank : 167)
Query Neighborhood Hits	109	Target Neighborhood Hits	2073	Shared Neighborhood Hits	41
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

SPG21_MOUSE
θ value	5.27518 (rank : 94)	NC score	0.024450 (rank : 161)
Query Neighborhood Hits	109	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQC8, Q3U658, Q3UDT7, Q8C1Y7	Gene names	Spg21
Domain Architecture	No domain graphic available
Description	Maspardin (Spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog) (Acid cluster protein 33).

ATS5_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.004311 (rank : 182)
Query Neighborhood Hits	109	Target Neighborhood Hits	147	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

CCNL1_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.008863 (rank : 177)
Query Neighborhood Hits	109	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

I12R2_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.004300 (rank : 183)
Query Neighborhood Hits	109	Target Neighborhood Hits	143	Shared Neighborhood Hits	3
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

IFT74_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.038498 (rank : 147)
Query Neighborhood Hits	109	Target Neighborhood Hits	949	Shared Neighborhood Hits	33
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

MYO15_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.007613 (rank : 179)
Query Neighborhood Hits	109	Target Neighborhood Hits	671	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PKHC1_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.036176 (rank : 149)
Query Neighborhood Hits	109	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q96AC1, Q14840, Q86TY7	Gene names	PLEKHC1, KIND2, MIG2
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1 (Kindlin-2) (Mitogen-inducible gene 2 protein) (Mig-2).

AP3D1_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.018159 (rank : 165)
Query Neighborhood Hits	109	Target Neighborhood Hits	254	Shared Neighborhood Hits	9
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

CCD46_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.041380 (rank : 141)
Query Neighborhood Hits	109	Target Neighborhood Hits	1405	Shared Neighborhood Hits	38
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CCNL1_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.008289 (rank : 178)
Query Neighborhood Hits	109	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	Q52KE7, Q8BQ75, Q8R5H9, Q922K0, Q9CSZ3, Q9WV44	Gene names	Ccnl1, Ania6a, Ccn1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a).

GAS8_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.042397 (rank : 140)
Query Neighborhood Hits	109	Target Neighborhood Hits	819	Shared Neighborhood Hits	35
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

K1267_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.006802 (rank : 180)
Query Neighborhood Hits	109	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TG1, Q3TT88, Q3U5D8, Q3V3N3, Q7TMU3, Q80XP7, Q8R3L6, Q9D9G0	Gene names	Kiaa1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

PKHC1_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.032431 (rank : 156)
Query Neighborhood Hits	109	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CIB5, Q8C542, Q8K035	Gene names	Plekhc1
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1.

SON_HUMAN
θ value	8.99809 (rank : 107)	NC score	-0.002116 (rank : 188)
Query Neighborhood Hits	109	Target Neighborhood Hits	1568	Shared Neighborhood Hits	12
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TPR_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.039797 (rank : 144)
Query Neighborhood Hits	109	Target Neighborhood Hits	1921	Shared Neighborhood Hits	41
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRI59_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.012528 (rank : 173)
Query Neighborhood Hits	109	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

CCD11_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.061161 (rank : 105)
Query Neighborhood Hits	109	Target Neighborhood Hits	822	Shared Neighborhood Hits	33
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD50_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.059353 (rank : 110)
Query Neighborhood Hits	109	Target Neighborhood Hits	237	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CCD91_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.054766 (rank : 117)
Query Neighborhood Hits	109	Target Neighborhood Hits	868	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CD45_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.089034 (rank : 86)
Query Neighborhood Hits	109	Target Neighborhood Hits	243	Shared Neighborhood Hits	10
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD45_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.092278 (rank : 75)
Query Neighborhood Hits	109	Target Neighborhood Hits	178	Shared Neighborhood Hits	13
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

CDC37_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.052931 (rank : 123)
Query Neighborhood Hits	109	Target Neighborhood Hits	506	Shared Neighborhood Hits	24
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

CK5P2_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.050814 (rank : 128)
Query Neighborhood Hits	109	Target Neighborhood Hits	1433	Shared Neighborhood Hits	37
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CLCB_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.051872 (rank : 125)
Query Neighborhood Hits	109	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	Q6IRU5, Q8BR04, Q8CDX9, Q9CV35	Gene names	Cltb
Domain Architecture	No domain graphic available
Description	Clathrin light chain B (Lcb).

CT2NL_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.060148 (rank : 109)
Query Neighborhood Hits	109	Target Neighborhood Hits	1059	Shared Neighborhood Hits	40
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CT2NL_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.060908 (rank : 107)
Query Neighborhood Hits	109	Target Neighborhood Hits	902	Shared Neighborhood Hits	36
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

HIP1R_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.062647 (rank : 103)
Query Neighborhood Hits	109	Target Neighborhood Hits	809	Shared Neighborhood Hits	36
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1R_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.058292 (rank : 114)
Query Neighborhood Hits	109	Target Neighborhood Hits	959	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

HIP1_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.064007 (rank : 101)
Query Neighborhood Hits	109	Target Neighborhood Hits	1016	Shared Neighborhood Hits	39
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

KRIT1_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.108879 (rank : 50)
Query Neighborhood Hits	109	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

KRIT1_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.090221 (rank : 84)
Query Neighborhood Hits	109	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

NAF1_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.062949 (rank : 102)
Query Neighborhood Hits	109	Target Neighborhood Hits	937	Shared Neighborhood Hits	35
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NEB2_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.053321 (rank : 121)
Query Neighborhood Hits	109	Target Neighborhood Hits	883	Shared Neighborhood Hits	35
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.050613 (rank : 131)
Query Neighborhood Hits	109	Target Neighborhood Hits	889	Shared Neighborhood Hits	34
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PTN11_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.092104 (rank : 78)
Query Neighborhood Hits	109	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.092094 (rank : 79)
Query Neighborhood Hits	109	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN12_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.097636 (rank : 65)
Query Neighborhood Hits	109	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.097333 (rank : 66)
Query Neighborhood Hits	109	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN18_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.105312 (rank : 54)
Query Neighborhood Hits	109	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.102082 (rank : 57)
Query Neighborhood Hits	109	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN1_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.105543 (rank : 53)
Query Neighborhood Hits	109	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.105856 (rank : 52)
Query Neighborhood Hits	109	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN22_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.099197 (rank : 59)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN22_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.097852 (rank : 64)
Query Neighborhood Hits	109	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN23_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.092684 (rank : 74)
Query Neighborhood Hits	109	Target Neighborhood Hits	646	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.091769 (rank : 80)
Query Neighborhood Hits	109	Target Neighborhood Hits	726	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN2_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.105286 (rank : 55)
Query Neighborhood Hits	109	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN2_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.106466 (rank : 51)
Query Neighborhood Hits	109	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN5_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.092232 (rank : 76)
Query Neighborhood Hits	109	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.092186 (rank : 77)
Query Neighborhood Hits	109	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN6_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.097942 (rank : 62)
Query Neighborhood Hits	109	Target Neighborhood Hits	234	Shared Neighborhood Hits	9
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.097966 (rank : 61)
Query Neighborhood Hits	109	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN7_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.097934 (rank : 63)
Query Neighborhood Hits	109	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.098929 (rank : 60)
Query Neighborhood Hits	109	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN9_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.102114 (rank : 56)
Query Neighborhood Hits	109	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.101787 (rank : 58)
Query Neighborhood Hits	109	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPR2_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.094255 (rank : 71)
Query Neighborhood Hits	109	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.094401 (rank : 70)
Query Neighborhood Hits	109	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRA_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.085337 (rank : 88)
Query Neighborhood Hits	109	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.085163 (rank : 89)
Query Neighborhood Hits	109	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRB_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.089950 (rank : 85)
Query Neighborhood Hits	109	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRD_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.060883 (rank : 108)
Query Neighborhood Hits	109	Target Neighborhood Hits	485	Shared Neighborhood Hits	11
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.058408 (rank : 112)
Query Neighborhood Hits	109	Target Neighborhood Hits	491	Shared Neighborhood Hits	11
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRE_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.085469 (rank : 87)
Query Neighborhood Hits	109	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.085050 (rank : 90)
Query Neighborhood Hits	109	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRF_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.058407 (rank : 113)
Query Neighborhood Hits	109	Target Neighborhood Hits	489	Shared Neighborhood Hits	10
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRG_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.075717 (rank : 95)
Query Neighborhood Hits	109	Target Neighborhood Hits	231	Shared Neighborhood Hits	10
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.075927 (rank : 94)
Query Neighborhood Hits	109	Target Neighborhood Hits	260	Shared Neighborhood Hits	12
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRJ_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.091344 (rank : 82)
Query Neighborhood Hits	109	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRJ_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.091707 (rank : 81)
Query Neighborhood Hits	109	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRK_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.076703 (rank : 92)
Query Neighborhood Hits	109	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.077381 (rank : 91)
Query Neighborhood Hits	109	Target Neighborhood Hits	223	Shared Neighborhood Hits	9
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRM_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.072288 (rank : 99)
Query Neighborhood Hits	109	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.072641 (rank : 98)
Query Neighborhood Hits	109	Target Neighborhood Hits	238	Shared Neighborhood Hits	9
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRN_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.094796 (rank : 68)
Query Neighborhood Hits	109	Target Neighborhood Hits	156	Shared Neighborhood Hits	9
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.094678 (rank : 69)
Query Neighborhood Hits	109	Target Neighborhood Hits	240	Shared Neighborhood Hits	9
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRO_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.095512 (rank : 67)
Query Neighborhood Hits	109	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRR_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.093729 (rank : 73)
Query Neighborhood Hits	109	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.094089 (rank : 72)
Query Neighborhood Hits	109	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRS_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.061117 (rank : 106)
Query Neighborhood Hits	109	Target Neighborhood Hits	472	Shared Neighborhood Hits	11
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRT_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.074382 (rank : 96)
Query Neighborhood Hits	109	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.074350 (rank : 97)
Query Neighborhood Hits	109	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRU_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.072115 (rank : 100)
Query Neighborhood Hits	109	Target Neighborhood Hits	237	Shared Neighborhood Hits	10
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRV_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.091124 (rank : 83)
Query Neighborhood Hits	109	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRZ_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.076491 (rank : 93)
Query Neighborhood Hits	109	Target Neighborhood Hits	255	Shared Neighborhood Hits	11
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

RFIP3_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.052098 (rank : 124)
Query Neighborhood Hits	109	Target Neighborhood Hits	1055	Shared Neighborhood Hits	35
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

RIMB1_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.054533 (rank : 118)
Query Neighborhood Hits	109	Target Neighborhood Hits	1376	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SDCG8_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.055381 (rank : 116)
Query Neighborhood Hits	109	Target Neighborhood Hits	1002	Shared Neighborhood Hits	33
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SDCG8_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.053310 (rank : 122)
Query Neighborhood Hits	109	Target Neighborhood Hits	886	Shared Neighborhood Hits	32
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SPC24_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.056502 (rank : 115)
Query Neighborhood Hits	109	Target Neighborhood Hits	324	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

STXB4_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.053793 (rank : 120)
Query Neighborhood Hits	109	Target Neighborhood Hits	616	Shared Neighborhood Hits	33
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

TAXB1_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.050501 (rank : 132)
Query Neighborhood Hits	109	Target Neighborhood Hits	829	Shared Neighborhood Hits	33
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TPM4_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.059261 (rank : 111)
Query Neighborhood Hits	109	Target Neighborhood Hits	703	Shared Neighborhood Hits	30
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

TUFT1_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.050765 (rank : 129)
Query Neighborhood Hits	109	Target Neighborhood Hits	732	Shared Neighborhood Hits	31
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

WDR67_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.051338 (rank : 127)
Query Neighborhood Hits	109	Target Neighborhood Hits	782	Shared Neighborhood Hits	31
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

ZWINT_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.054137 (rank : 119)
Query Neighborhood Hits	109	Target Neighborhood Hits	497	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

Hits sorted by NC score

FRM4B_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	109
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4B_HUMAN
NC score	0.996374 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	109	Target Neighborhood Hits	117	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4A_MOUSE
NC score	0.981828 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	109	Target Neighborhood Hits	108	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_HUMAN
NC score	0.981184 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	109	Target Neighborhood Hits	110	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRMD5_MOUSE
NC score	0.817589 (rank : 5)	θ value	2.20094e-22 (rank : 22)
Query Neighborhood Hits	109	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_HUMAN
NC score	0.817464 (rank : 6)	θ value	7.56453e-23 (rank : 18)
Query Neighborhood Hits	109	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41L5_HUMAN
NC score	0.809298 (rank : 7)	θ value	2.20094e-22 (rank : 21)
Query Neighborhood Hits	109	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LA_HUMAN
NC score	0.808257 (rank : 8)	θ value	9.24701e-21 (rank : 26)
Query Neighborhood Hits	109	Target Neighborhood Hits	87	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_MOUSE
NC score	0.807418 (rank : 9)	θ value	3.88503e-19 (rank : 35)
Query Neighborhood Hits	109	Target Neighborhood Hits	85	Shared Neighborhood Hits	49
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LB_MOUSE
NC score	0.803337 (rank : 10)	θ value	1.09232e-21 (rank : 23)
Query Neighborhood Hits	109	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

E41LB_HUMAN
NC score	0.794689 (rank : 11)	θ value	1.2077e-20 (rank : 28)
Query Neighborhood Hits	109	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

E41L1_MOUSE
NC score	0.791561 (rank : 12)	θ value	6.84181e-24 (rank : 14)
Query Neighborhood Hits	109	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_HUMAN
NC score	0.787868 (rank : 13)	θ value	3.07116e-24 (rank : 13)
Query Neighborhood Hits	109	Target Neighborhood Hits	180	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L3_HUMAN
NC score	0.787501 (rank : 14)	θ value	4.15078e-21 (rank : 24)
Query Neighborhood Hits	109	Target Neighborhood Hits	113	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

41_HUMAN
NC score	0.779284 (rank : 15)	θ value	1.02238e-19 (rank : 34)
Query Neighborhood Hits	109	Target Neighborhood Hits	157	Shared Neighborhood Hits	52
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

E41L3_MOUSE
NC score	0.774721 (rank : 16)	θ value	7.0802e-21 (rank : 25)
Query Neighborhood Hits	109	Target Neighborhood Hits	250	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

41_MOUSE
NC score	0.773500 (rank : 17)	θ value	8.65492e-19 (rank : 37)
Query Neighborhood Hits	109	Target Neighborhood Hits	184	Shared Neighborhood Hits	52
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

E41L2_HUMAN
NC score	0.772405 (rank : 18)	θ value	9.87957e-23 (rank : 20)
Query Neighborhood Hits	109	Target Neighborhood Hits	287	Shared Neighborhood Hits	58
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MERL_HUMAN
NC score	0.765439 (rank : 19)	θ value	8.3442e-30 (rank : 11)
Query Neighborhood Hits	109	Target Neighborhood Hits	532	Shared Neighborhood Hits	66
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
NC score	0.765181 (rank : 20)	θ value	3.17079e-29 (rank : 12)
Query Neighborhood Hits	109	Target Neighborhood Hits	524	Shared Neighborhood Hits	66
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MYLIP_MOUSE
NC score	0.763790 (rank : 21)	θ value	1.80466e-16 (rank : 41)
Query Neighborhood Hits	109	Target Neighborhood Hits	139	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

E41L2_MOUSE
NC score	0.750178 (rank : 22)	θ value	1.2077e-20 (rank : 27)
Query Neighborhood Hits	109	Target Neighborhood Hits	459	Shared Neighborhood Hits	54
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MYLIP_HUMAN
NC score	0.746396 (rank : 23)	θ value	5.8054e-15 (rank : 42)
Query Neighborhood Hits	109	Target Neighborhood Hits	162	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

EZRI_HUMAN
NC score	0.735666 (rank : 24)	θ value	3.27365e-34 (rank : 8)
Query Neighborhood Hits	109	Target Neighborhood Hits	663	Shared Neighborhood Hits	71
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
NC score	0.732047 (rank : 25)	θ value	1.12514e-34 (rank : 7)
Query Neighborhood Hits	109	Target Neighborhood Hits	693	Shared Neighborhood Hits	70
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

RADI_HUMAN
NC score	0.720874 (rank : 26)	θ value	5.0505e-35 (rank : 5)
Query Neighborhood Hits	109	Target Neighborhood Hits	741	Shared Neighborhood Hits	76
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
NC score	0.717732 (rank : 27)	θ value	5.0505e-35 (rank : 6)
Query Neighborhood Hits	109	Target Neighborhood Hits	773	Shared Neighborhood Hits	74
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

FRMD6_HUMAN
NC score	0.697860 (rank : 28)	θ value	1.09485e-13 (rank : 43)
Query Neighborhood Hits	109	Target Neighborhood Hits	60	Shared Neighborhood Hits	44
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

FRMD6_MOUSE
NC score	0.692317 (rank : 29)	θ value	6.00763e-12 (rank : 44)
Query Neighborhood Hits	109	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

MOES_HUMAN
NC score	0.678709 (rank : 30)	θ value	9.52487e-34 (rank : 9)
Query Neighborhood Hits	109	Target Neighborhood Hits	892	Shared Neighborhood Hits	74
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_MOUSE
NC score	0.670282 (rank : 31)	θ value	4.72714e-33 (rank : 10)
Query Neighborhood Hits	109	Target Neighborhood Hits	923	Shared Neighborhood Hits	74
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

FARP1_HUMAN
NC score	0.665356 (rank : 32)	θ value	3.88503e-19 (rank : 36)
Query Neighborhood Hits	109	Target Neighborhood Hits	241	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

FARP2_HUMAN
NC score	0.647414 (rank : 33)	θ value	7.82807e-20 (rank : 33)
Query Neighborhood Hits	109	Target Neighborhood Hits	240	Shared Neighborhood Hits	48
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FRMD1_HUMAN
NC score	0.640146 (rank : 34)	θ value	1.69304e-06 (rank : 45)
Query Neighborhood Hits	109	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

FARP2_MOUSE
NC score	0.636075 (rank : 35)	θ value	2.13179e-17 (rank : 39)
Query Neighborhood Hits	109	Target Neighborhood Hits	209	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

PTN21_MOUSE
NC score	0.565420 (rank : 36)	θ value	1.99067e-23 (rank : 15)
Query Neighborhood Hits	109	Target Neighborhood Hits	155	Shared Neighborhood Hits	48
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN4_HUMAN
NC score	0.563483 (rank : 37)	θ value	4.58923e-20 (rank : 32)
Query Neighborhood Hits	109	Target Neighborhood Hits	303	Shared Neighborhood Hits	48
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN21_HUMAN
NC score	0.562620 (rank : 38)	θ value	3.39556e-23 (rank : 17)
Query Neighborhood Hits	109	Target Neighborhood Hits	143	Shared Neighborhood Hits	48
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN14_MOUSE
NC score	0.554624 (rank : 39)	θ value	2.59989e-23 (rank : 16)
Query Neighborhood Hits	109	Target Neighborhood Hits	142	Shared Neighborhood Hits	47
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN3_HUMAN
NC score	0.553843 (rank : 40)	θ value	1.5773e-20 (rank : 29)
Query Neighborhood Hits	109	Target Neighborhood Hits	258	Shared Neighborhood Hits	48
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN14_HUMAN
NC score	0.548072 (rank : 41)	θ value	7.56453e-23 (rank : 19)
Query Neighborhood Hits	109	Target Neighborhood Hits	163	Shared Neighborhood Hits	47
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN13_MOUSE
NC score	0.452163 (rank : 42)	θ value	3.63628e-17 (rank : 40)
Query Neighborhood Hits	109	Target Neighborhood Hits	426	Shared Neighborhood Hits	50
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN13_HUMAN
NC score	0.443676 (rank : 43)	θ value	9.56915e-18 (rank : 38)
Query Neighborhood Hits	109	Target Neighborhood Hits	471	Shared Neighborhood Hits	52
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

CA106_HUMAN
NC score	0.438201 (rank : 44)	θ value	2.69047e-20 (rank : 30)
Query Neighborhood Hits	109	Target Neighborhood Hits	124	Shared Neighborhood Hits	8
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
NC score	0.434925 (rank : 45)	θ value	4.58923e-20 (rank : 31)
Query Neighborhood Hits	109	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

TLN2_MOUSE
NC score	0.360718 (rank : 46)	θ value	0.000786445 (rank : 47)
Query Neighborhood Hits	109	Target Neighborhood Hits	149	Shared Neighborhood Hits	52
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN1_HUMAN
NC score	0.355767 (rank : 47)	θ value	0.00665767 (rank : 49)
Query Neighborhood Hits	109	Target Neighborhood Hits	218	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN2_HUMAN
NC score	0.354471 (rank : 48)	θ value	0.00134147 (rank : 48)
Query Neighborhood Hits	109	Target Neighborhood Hits	157	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN1_MOUSE
NC score	0.353512 (rank : 49)	θ value	0.00665767 (rank : 50)
Query Neighborhood Hits	109	Target Neighborhood Hits	213	Shared Neighborhood Hits	50
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

KRIT1_HUMAN
NC score	0.108879 (rank : 50)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	109	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

PTN2_MOUSE
NC score	0.106466 (rank : 51)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	109	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN1_MOUSE
NC score	0.105856 (rank : 52)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	109	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN1_HUMAN
NC score	0.105543 (rank : 53)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	109	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN18_HUMAN
NC score	0.105312 (rank : 54)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	109	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN2_HUMAN
NC score	0.105286 (rank : 55)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	109	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN9_HUMAN
NC score	0.102114 (rank : 56)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	109	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN18_MOUSE
NC score	0.102082 (rank : 57)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	109	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN9_MOUSE
NC score	0.101787 (rank : 58)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	109	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN22_HUMAN
NC score	0.099197 (rank : 59)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN7_MOUSE
NC score	0.098929 (rank : 60)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	109	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN6_MOUSE
NC score	0.097966 (rank : 61)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	109	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN6_HUMAN
NC score	0.097942 (rank : 62)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	109	Target Neighborhood Hits	234	Shared Neighborhood Hits	9
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN7_HUMAN
NC score	0.097934 (rank : 63)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	109	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN22_MOUSE
NC score	0.097852 (rank : 64)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	109	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN12_HUMAN
NC score	0.097636 (rank : 65)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	109	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
NC score	0.097333 (rank : 66)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	109	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTPRO_HUMAN
NC score	0.095512 (rank : 67)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	109	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRN_HUMAN
NC score	0.094796 (rank : 68)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	109	Target Neighborhood Hits	156	Shared Neighborhood Hits	9
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
NC score	0.094678 (rank : 69)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	109	Target Neighborhood Hits	240	Shared Neighborhood Hits	9
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPR2_MOUSE
NC score	0.094401 (rank : 70)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	109	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPR2_HUMAN
NC score	0.094255 (rank : 71)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	109	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPRR_MOUSE
NC score	0.094089 (rank : 72)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	109	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRR_HUMAN
NC score	0.093729 (rank : 73)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	109	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTN23_HUMAN
NC score	0.092684 (rank : 74)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	109	Target Neighborhood Hits	646	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

CD45_MOUSE
NC score	0.092278 (rank : 75)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	109	Target Neighborhood Hits	178	Shared Neighborhood Hits	13
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTN5_HUMAN
NC score	0.092232 (rank : 76)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	109	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
NC score	0.092186 (rank : 77)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	109	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN11_HUMAN
NC score	0.092104 (rank : 78)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	109	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
NC score	0.092094 (rank : 79)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	109	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN23_MOUSE
NC score	0.091769 (rank : 80)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	109	Target Neighborhood Hits	726	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTPRJ_MOUSE
NC score	0.091707 (rank : 81)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	109	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRJ_HUMAN
NC score	0.091344 (rank : 82)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	109	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRV_MOUSE
NC score	0.091124 (rank : 83)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	109	Target Neighborhood Hits	179	Shared Neighborhood Hits	9
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

KRIT1_MOUSE
NC score	0.090221 (rank : 84)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	109	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

PTPRB_HUMAN
NC score	0.089950 (rank : 85)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	109	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

CD45_HUMAN
NC score	0.089034 (rank : 86)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	109	Target Neighborhood Hits	243	Shared Neighborhood Hits	10
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTPRE_HUMAN
NC score	0.085469 (rank : 87)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	109	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_HUMAN
NC score	0.085337 (rank : 88)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	109	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
NC score	0.085163 (rank : 89)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	109	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRE_MOUSE
NC score	0.085050 (rank : 90)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	109	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRK_MOUSE
NC score	0.077381 (rank : 91)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	109	Target Neighborhood Hits	223	Shared Neighborhood Hits	9
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_HUMAN
NC score	0.076703 (rank : 92)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	109	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRZ_HUMAN
NC score	0.076491 (rank : 93)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	109	Target Neighborhood Hits	255	Shared Neighborhood Hits	11
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTPRG_MOUSE
NC score	0.075927 (rank : 94)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	109	Target Neighborhood Hits	260	Shared Neighborhood Hits	12
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_HUMAN
NC score	0.075717 (rank : 95)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	109	Target Neighborhood Hits	231	Shared Neighborhood Hits	10
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRT_HUMAN
NC score	0.074382 (rank : 96)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	109	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
NC score	0.074350 (rank : 97)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	109	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRM_MOUSE
NC score	0.072641 (rank : 98)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	109	Target Neighborhood Hits	238	Shared Neighborhood Hits	9
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_HUMAN
NC score	0.072288 (rank : 99)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	109	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRU_HUMAN
NC score	0.072115 (rank : 100)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	109	Target Neighborhood Hits	237	Shared Neighborhood Hits	10
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

HIP1_HUMAN
NC score	0.064007 (rank : 101)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	109	Target Neighborhood Hits	1016	Shared Neighborhood Hits	39
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

NAF1_HUMAN
NC score	0.062949 (rank : 102)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	109	Target Neighborhood Hits	937	Shared Neighborhood Hits	35
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

HIP1R_HUMAN
NC score	0.062647 (rank : 103)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	109	Target Neighborhood Hits	809	Shared Neighborhood Hits	36
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

MYO10_HUMAN
NC score	0.061777 (rank : 104)	θ value	0.00020696 (rank : 46)
Query Neighborhood Hits	109	Target Neighborhood Hits	920	Shared Neighborhood Hits	46
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

CCD11_HUMAN
NC score	0.061161 (rank : 105)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	109	Target Neighborhood Hits	822	Shared Neighborhood Hits	33
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

PTPRS_HUMAN
NC score	0.061117 (rank : 106)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	109	Target Neighborhood Hits	472	Shared Neighborhood Hits	11
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

CT2NL_MOUSE
NC score	0.060908 (rank : 107)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	109	Target Neighborhood Hits	902	Shared Neighborhood Hits	36
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

PTPRD_HUMAN
NC score	0.060883 (rank : 108)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	109	Target Neighborhood Hits	485	Shared Neighborhood Hits	11
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

CT2NL_HUMAN
NC score	0.060148 (rank : 109)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	109	Target Neighborhood Hits	1059	Shared Neighborhood Hits	40
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CCD50_HUMAN
NC score	0.059353 (rank : 110)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	109	Target Neighborhood Hits	237	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

TPM4_MOUSE
NC score	0.059261 (rank : 111)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	109	Target Neighborhood Hits	703	Shared Neighborhood Hits	30
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

PTPRD_MOUSE
NC score	0.058408 (rank : 112)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	109	Target Neighborhood Hits	491	Shared Neighborhood Hits	11
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRF_HUMAN
NC score	0.058407 (rank : 113)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	109	Target Neighborhood Hits	489	Shared Neighborhood Hits	10
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

HIP1R_MOUSE
NC score	0.058292 (rank : 114)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	109	Target Neighborhood Hits	959	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

SPC24_HUMAN
NC score	0.056502 (rank : 115)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	109	Target Neighborhood Hits	324	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NBT2	Gene names	SPBC24
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc24 (hSpc24).

SDCG8_HUMAN
NC score	0.055381 (rank : 116)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	109	Target Neighborhood Hits	1002	Shared Neighborhood Hits	33
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

CCD91_HUMAN
NC score	0.054766 (rank : 117)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	109	Target Neighborhood Hits	868	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

RIMB1_MOUSE
NC score	0.054533 (rank : 118)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	109	Target Neighborhood Hits	1376	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ZWINT_MOUSE
NC score	0.054137 (rank : 119)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	109	Target Neighborhood Hits	497	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

STXB4_HUMAN
NC score	0.053793 (rank : 120)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	109	Target Neighborhood Hits	616	Shared Neighborhood Hits	33
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

NEB2_HUMAN
NC score	0.053321 (rank : 121)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	109	Target Neighborhood Hits	883	Shared Neighborhood Hits	35
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

SDCG8_MOUSE
NC score	0.053310 (rank : 122)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	109	Target Neighborhood Hits	886	Shared Neighborhood Hits	32
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

CDC37_HUMAN
NC score	0.052931 (rank : 123)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	109	Target Neighborhood Hits	506	Shared Neighborhood Hits	24
SwissProt Accessions	Q16543	Gene names	CDC37
Domain Architecture
Description	Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37).

RFIP3_HUMAN
NC score	0.052098 (rank : 124)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	109	Target Neighborhood Hits	1055	Shared Neighborhood Hits	35
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

CLCB_MOUSE
NC score	0.051872 (rank : 125)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	109	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	Q6IRU5, Q8BR04, Q8CDX9, Q9CV35	Gene names	Cltb
Domain Architecture	No domain graphic available
Description	Clathrin light chain B (Lcb).

GOGA4_HUMAN
NC score	0.051746 (rank : 126)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	109	Target Neighborhood Hits	2034	Shared Neighborhood Hits	44
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

WDR67_HUMAN
NC score	0.051338 (rank : 127)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	109	Target Neighborhood Hits	782	Shared Neighborhood Hits	31
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

CK5P2_HUMAN
NC score	0.050814 (rank : 128)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	109	Target Neighborhood Hits	1433	Shared Neighborhood Hits	37
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

TUFT1_MOUSE
NC score	0.050765 (rank : 129)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	109	Target Neighborhood Hits	732	Shared Neighborhood Hits	31
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

CCD45_MOUSE
NC score	0.050661 (rank : 130)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	109	Target Neighborhood Hits	663	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

NEB2_MOUSE
NC score	0.050613 (rank : 131)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	109	Target Neighborhood Hits	889	Shared Neighborhood Hits	34
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

TAXB1_HUMAN
NC score	0.050501 (rank : 132)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	109	Target Neighborhood Hits	829	Shared Neighborhood Hits	33
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

PKHA6_MOUSE
NC score	0.049982 (rank : 133)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	109	Target Neighborhood Hits	591	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CCD46_HUMAN
NC score	0.048381 (rank : 134)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	109	Target Neighborhood Hits	1430	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

SMC2_HUMAN
NC score	0.046665 (rank : 135)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	109	Target Neighborhood Hits	1405	Shared Neighborhood Hits	42
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

CF182_MOUSE
NC score	0.045770 (rank : 136)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	109	Target Neighborhood Hits	551	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

CENPE_HUMAN
NC score	0.043335 (rank : 137)	θ value	0.163984 (rank : 52)
Query Neighborhood Hits	109	Target Neighborhood Hits	2060	Shared Neighborhood Hits	46
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

PEPL_MOUSE
NC score	0.043293 (rank : 138)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	109	Target Neighborhood Hits	1105	Shared Neighborhood Hits	37
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

CP135_MOUSE
NC score	0.042886 (rank : 139)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	109	Target Neighborhood Hits	1278	Shared Neighborhood Hits	39
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

GAS8_HUMAN
NC score	0.042397 (rank : 140)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	109	Target Neighborhood Hits	819	Shared Neighborhood Hits	35
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

CCD46_MOUSE
NC score	0.041380 (rank : 141)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	109	Target Neighborhood Hits	1405	Shared Neighborhood Hits	38
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

RBP24_HUMAN
NC score	0.040799 (rank : 142)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	109	Target Neighborhood Hits	1559	Shared Neighborhood Hits	42
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.040737 (rank : 143)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	109	Target Neighborhood Hits	1558	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

TPR_HUMAN
NC score	0.039797 (rank : 144)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	109	Target Neighborhood Hits	1921	Shared Neighborhood Hits	41
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

PEPL_HUMAN
NC score	0.039553 (rank : 145)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	109	Target Neighborhood Hits	1141	Shared Neighborhood Hits	36
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

GOGA1_MOUSE
NC score	0.039363 (rank : 146)	θ value	0.62314 (rank : 62)
Query Neighborhood Hits	109	Target Neighborhood Hits	994	Shared Neighborhood Hits	36
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

IFT74_HUMAN
NC score	0.038498 (rank : 147)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	109	Target Neighborhood Hits	949	Shared Neighborhood Hits	33
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

PESC_MOUSE
NC score	0.036754 (rank : 148)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EQ61, Q542F0	Gene names	Pes1
Domain Architecture
Description	Pescadillo homolog 1.

PKHC1_HUMAN
NC score	0.036176 (rank : 149)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	109	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	Q96AC1, Q14840, Q86TY7	Gene names	PLEKHC1, KIND2, MIG2
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1 (Kindlin-2) (Mitogen-inducible gene 2 protein) (Mig-2).

THSD1_MOUSE
NC score	0.035887 (rank : 150)	θ value	0.365318 (rank : 54)
Query Neighborhood Hits	109	Target Neighborhood Hits	153	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

CCD38_HUMAN
NC score	0.035665 (rank : 151)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	109	Target Neighborhood Hits	287	Shared Neighborhood Hits	22
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

IFT74_MOUSE
NC score	0.034620 (rank : 152)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	109	Target Neighborhood Hits	939	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

FYCO1_HUMAN
NC score	0.034071 (rank : 153)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	109	Target Neighborhood Hits	1149	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

MCES_HUMAN
NC score	0.033751 (rank : 154)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	109	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	O43148, O94996, Q9UIJ9	Gene names	RNMT, KIAA0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase) (hcm1p) (hCMT1) (hMet).

MYO5C_HUMAN
NC score	0.033143 (rank : 155)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	109	Target Neighborhood Hits	1206	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

PKHC1_MOUSE
NC score	0.032431 (rank : 156)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	109	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CIB5, Q8C542, Q8K035	Gene names	Plekhc1
Domain Architecture
Description	Pleckstrin homology domain-containing family C member 1.

KINH_HUMAN
NC score	0.031584 (rank : 157)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	109	Target Neighborhood Hits	1231	Shared Neighborhood Hits	34
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

KINH_MOUSE
NC score	0.029763 (rank : 158)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	109	Target Neighborhood Hits	1082	Shared Neighborhood Hits	34
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

THAP6_HUMAN
NC score	0.029696 (rank : 159)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	109	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TBB0	Gene names	THAP6
Domain Architecture
Description	THAP domain-containing protein 6.

SPG21_HUMAN
NC score	0.026561 (rank : 160)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	109	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZD8, Q6ZMB6	Gene names	SPG21, ACP33
Domain Architecture	No domain graphic available
Description	Maspardin (Spastic paraplegia 21 autosomal recessive Mast syndrome protein) (Acid cluster protein 33).

SPG21_MOUSE
NC score	0.024450 (rank : 161)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	109	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQC8, Q3U658, Q3UDT7, Q8C1Y7	Gene names	Spg21
Domain Architecture	No domain graphic available
Description	Maspardin (Spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog) (Acid cluster protein 33).

ZO1_HUMAN
NC score	0.023395 (rank : 162)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	109	Target Neighborhood Hits	474	Shared Neighborhood Hits	8
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

LUZP1_MOUSE
NC score	0.021436 (rank : 163)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	109	Target Neighborhood Hits	940	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

GPTC8_HUMAN
NC score	0.020251 (rank : 164)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	109	Target Neighborhood Hits	366	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

AP3D1_HUMAN
NC score	0.018159 (rank : 165)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	109	Target Neighborhood Hits	254	Shared Neighborhood Hits	9
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

VGLL2_MOUSE
NC score	0.017577 (rank : 166)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	109	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGW8, Q8BWB4	Gene names	Vgll2, Vgl2, Vito1
Domain Architecture	No domain graphic available
Description	Transcription cofactor vestigial-like protein 2 (Vgl-2) (Protein VITO1).

ROCK2_HUMAN
NC score	0.016098 (rank : 167)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	109	Target Neighborhood Hits	2073	Shared Neighborhood Hits	41
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

REXO4_MOUSE
NC score	0.014437 (rank : 168)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	109	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PAQ4, Q3UU17, Q8C524	Gene names	Rexo4, Gm111, Pmc2, Xpmc2h
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein homolog).

TRPM6_MOUSE
NC score	0.014005 (rank : 169)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	109	Target Neighborhood Hits	78	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

DPOLZ_HUMAN
NC score	0.013921 (rank : 170)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	109	Target Neighborhood Hits	200	Shared Neighborhood Hits	12
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

FILA_HUMAN
NC score	0.013131 (rank : 171)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	109	Target Neighborhood Hits	685	Shared Neighborhood Hits	20
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

DNJC3_HUMAN
NC score	0.012901 (rank : 172)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	109	Target Neighborhood Hits	223	Shared Neighborhood Hits	7
SwissProt Accessions	Q13217, Q86WT9, Q8N4N2	Gene names	DNAJC3, P58IPK, PRKRI
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

TRI59_MOUSE
NC score	0.012528 (rank : 173)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	109	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TGON2_HUMAN
NC score	0.011459 (rank : 174)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	109	Target Neighborhood Hits	1037	Shared Neighborhood Hits	20
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CHD9_MOUSE
NC score	0.011022 (rank : 175)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	109	Target Neighborhood Hits	427	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

VDR_HUMAN
NC score	0.009108 (rank : 176)	θ value	0.125558 (rank : 51)
Query Neighborhood Hits	109	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

CCNL1_HUMAN
NC score	0.008863 (rank : 177)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	109	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

CCNL1_MOUSE
NC score	0.008289 (rank : 178)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	109	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	Q52KE7, Q8BQ75, Q8R5H9, Q922K0, Q9CSZ3, Q9WV44	Gene names	Ccnl1, Ania6a, Ccn1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a).

MYO15_HUMAN
NC score	0.007613 (rank : 179)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	109	Target Neighborhood Hits	671	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

K1267_MOUSE
NC score	0.006802 (rank : 180)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	109	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TG1, Q3TT88, Q3U5D8, Q3V3N3, Q7TMU3, Q80XP7, Q8R3L6, Q9D9G0	Gene names	Kiaa1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

ATS5_HUMAN
NC score	0.005492 (rank : 181)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	109	Target Neighborhood Hits	141	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS5_MOUSE
NC score	0.004311 (rank : 182)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	109	Target Neighborhood Hits	147	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

I12R2_MOUSE
NC score	0.004300 (rank : 183)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	109	Target Neighborhood Hits	143	Shared Neighborhood Hits	3
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

WNK2_HUMAN
NC score	0.001329 (rank : 184)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	109	Target Neighborhood Hits	1407	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

PAK7_MOUSE
NC score	-0.000512 (rank : 185)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	109	Target Neighborhood Hits	875	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C015, Q3TQJ7, Q6RWS7	Gene names	Pak7, Pak5
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5).

DCC_HUMAN
NC score	-0.000651 (rank : 186)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	109	Target Neighborhood Hits	583	Shared Neighborhood Hits	4
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

PAK7_HUMAN
NC score	-0.001790 (rank : 187)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	109	Target Neighborhood Hits	875	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P286, Q5W115, Q9BX09, Q9ULF6	Gene names	PAK7, KIAA1264, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (PAK-5).

SON_HUMAN
NC score	-0.002116 (rank : 188)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	109	Target Neighborhood Hits	1568	Shared Neighborhood Hits	12
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ZN519_HUMAN
NC score	-0.005018 (rank : 189)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	109	Target Neighborhood Hits	738	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TB69	Gene names	ZNF519
Domain Architecture
Description	Zinc finger protein 519.