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Network neighborhood for query Sequence : TRPM6_MOUSE

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TRPM6_MOUSE
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRPM3_HUMAN
θ value	0 (rank : 1)	NC score	0.959760 (rank : 5)
Query Neighborhood Hits	78	Target Neighborhood Hits	121	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TRPM6_HUMAN
θ value	0 (rank : 2)	NC score	0.990346 (rank : 2)
Query Neighborhood Hits	78	Target Neighborhood Hits	91	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM6_MOUSE
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	78
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM7_HUMAN
θ value	0 (rank : 4)	NC score	0.977476 (rank : 4)
Query Neighborhood Hits	78	Target Neighborhood Hits	104	Shared Neighborhood Hits	35
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM7_MOUSE
θ value	0 (rank : 5)	NC score	0.978272 (rank : 3)
Query Neighborhood Hits	78	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TRPM8_HUMAN
θ value	1.3939e-101 (rank : 6)	NC score	0.848768 (rank : 7)
Query Neighborhood Hits	78	Target Neighborhood Hits	65	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

TRPM2_MOUSE
θ value	9.056e-93 (rank : 7)	NC score	0.851060 (rank : 6)
Query Neighborhood Hits	78	Target Neighborhood Hits	61	Shared Neighborhood Hits	30
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPM2_HUMAN
θ value	1.44581e-90 (rank : 8)	NC score	0.847341 (rank : 8)
Query Neighborhood Hits	78	Target Neighborhood Hits	64	Shared Neighborhood Hits	29
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TRPM8_MOUSE
θ value	2.18062e-54 (rank : 9)	NC score	0.843088 (rank : 9)
Query Neighborhood Hits	78	Target Neighborhood Hits	58	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TRPC4_MOUSE
θ value	4.02038e-16 (rank : 10)	NC score	0.486156 (rank : 11)
Query Neighborhood Hits	78	Target Neighborhood Hits	141	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC4_HUMAN
θ value	5.25075e-16 (rank : 11)	NC score	0.487317 (rank : 10)
Query Neighborhood Hits	78	Target Neighborhood Hits	140	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC5_HUMAN
θ value	1.68911e-14 (rank : 12)	NC score	0.470178 (rank : 13)
Query Neighborhood Hits	78	Target Neighborhood Hits	122	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC5_MOUSE
θ value	1.68911e-14 (rank : 13)	NC score	0.470499 (rank : 12)
Query Neighborhood Hits	78	Target Neighborhood Hits	124	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

EF2K_MOUSE
θ value	4.59992e-12 (rank : 14)	NC score	0.343178 (rank : 23)
Query Neighborhood Hits	78	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	O08796	Gene names	Eef2k
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

EF2K_HUMAN
θ value	5.08577e-11 (rank : 15)	NC score	0.334990 (rank : 24)
Query Neighborhood Hits	78	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	O00418	Gene names	EEF2K
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

TRPC2_MOUSE
θ value	2.36244e-08 (rank : 16)	NC score	0.435137 (rank : 14)
Query Neighborhood Hits	78	Target Neighborhood Hits	84	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TRPC3_MOUSE
θ value	2.36244e-08 (rank : 17)	NC score	0.405864 (rank : 15)
Query Neighborhood Hits	78	Target Neighborhood Hits	131	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC7_HUMAN
θ value	1.99992e-07 (rank : 18)	NC score	0.366325 (rank : 20)
Query Neighborhood Hits	78	Target Neighborhood Hits	123	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC7_MOUSE
θ value	1.99992e-07 (rank : 19)	NC score	0.367226 (rank : 19)
Query Neighborhood Hits	78	Target Neighborhood Hits	114	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC6_HUMAN
θ value	2.61198e-07 (rank : 20)	NC score	0.374651 (rank : 18)
Query Neighborhood Hits	78	Target Neighborhood Hits	171	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC6_MOUSE
θ value	2.61198e-07 (rank : 21)	NC score	0.375315 (rank : 17)
Query Neighborhood Hits	78	Target Neighborhood Hits	171	Shared Neighborhood Hits	33
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC3_HUMAN
θ value	5.81887e-07 (rank : 22)	NC score	0.394975 (rank : 16)
Query Neighborhood Hits	78	Target Neighborhood Hits	137	Shared Neighborhood Hits	29
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPV3_MOUSE
θ value	3.19293e-05 (rank : 23)	NC score	0.222551 (rank : 25)
Query Neighborhood Hits	78	Target Neighborhood Hits	188	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV3_HUMAN
θ value	7.1131e-05 (rank : 24)	NC score	0.221802 (rank : 26)
Query Neighborhood Hits	78	Target Neighborhood Hits	198	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPC1_HUMAN
θ value	0.000461057 (rank : 25)	NC score	0.346053 (rank : 22)
Query Neighborhood Hits	78	Target Neighborhood Hits	91	Shared Neighborhood Hits	31
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC1_MOUSE
θ value	0.000461057 (rank : 26)	NC score	0.346213 (rank : 21)
Query Neighborhood Hits	78	Target Neighborhood Hits	87	Shared Neighborhood Hits	29
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPV5_HUMAN
θ value	0.00869519 (rank : 27)	NC score	0.142239 (rank : 30)
Query Neighborhood Hits	78	Target Neighborhood Hits	261	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV6_HUMAN
θ value	0.0148317 (rank : 28)	NC score	0.158423 (rank : 27)
Query Neighborhood Hits	78	Target Neighborhood Hits	262	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV6_MOUSE
θ value	0.0252991 (rank : 29)	NC score	0.144289 (rank : 29)
Query Neighborhood Hits	78	Target Neighborhood Hits	284	Shared Neighborhood Hits	31
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

TRPV5_MOUSE
θ value	0.0563607 (rank : 30)	NC score	0.135403 (rank : 34)
Query Neighborhood Hits	78	Target Neighborhood Hits	278	Shared Neighborhood Hits	30
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

CNGA1_MOUSE
θ value	0.0961366 (rank : 31)	NC score	0.020231 (rank : 47)
Query Neighborhood Hits	78	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CSPG2_HUMAN
θ value	0.279714 (rank : 32)	NC score	0.008680 (rank : 69)
Query Neighborhood Hits	78	Target Neighborhood Hits	681	Shared Neighborhood Hits	4
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

UBP37_HUMAN
θ value	0.365318 (rank : 33)	NC score	0.016825 (rank : 50)
Query Neighborhood Hits	78	Target Neighborhood Hits	208	Shared Neighborhood Hits	7
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

FRM4B_HUMAN
θ value	0.47712 (rank : 34)	NC score	0.016908 (rank : 49)
Query Neighborhood Hits	78	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

SYCP1_MOUSE
θ value	0.47712 (rank : 35)	NC score	0.012409 (rank : 58)
Query Neighborhood Hits	78	Target Neighborhood Hits	1456	Shared Neighborhood Hits	26
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CNGA1_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.023862 (rank : 46)
Query Neighborhood Hits	78	Target Neighborhood Hits	149	Shared Neighborhood Hits	5
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

COHA1_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.008120 (rank : 74)
Query Neighborhood Hits	78	Target Neighborhood Hits	400	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

LRSM1_HUMAN
θ value	1.38821 (rank : 38)	NC score	0.010371 (rank : 66)
Query Neighborhood Hits	78	Target Neighborhood Hits	1078	Shared Neighborhood Hits	22
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

NUCL_MOUSE
θ value	1.38821 (rank : 39)	NC score	0.008629 (rank : 70)
Query Neighborhood Hits	78	Target Neighborhood Hits	425	Shared Neighborhood Hits	5
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

CBPB2_MOUSE
θ value	1.81305 (rank : 40)	NC score	0.009012 (rank : 68)
Query Neighborhood Hits	78	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHH6, Q5EBI3, Q9QZF0	Gene names	Cpb2, Tafi
Domain Architecture	No domain graphic available
Description	Carboxypeptidase B2 precursor (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) (Carboxypeptidase R) (CPR).

DMD_MOUSE
θ value	1.81305 (rank : 41)	NC score	0.010958 (rank : 65)
Query Neighborhood Hits	78	Target Neighborhood Hits	1111	Shared Neighborhood Hits	25
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

INP4A_MOUSE
θ value	1.81305 (rank : 42)	NC score	0.013718 (rank : 54)
Query Neighborhood Hits	78	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPW0, Q8CBJ8	Gene names	Inpp4a
Domain Architecture	No domain graphic available
Description	Type I inositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type I).

PCNT_MOUSE
θ value	1.81305 (rank : 43)	NC score	0.032488 (rank : 43)
Query Neighborhood Hits	78	Target Neighborhood Hits	1207	Shared Neighborhood Hits	24
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

SYNE1_HUMAN
θ value	1.81305 (rank : 44)	NC score	0.015445 (rank : 52)
Query Neighborhood Hits	78	Target Neighborhood Hits	1484	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TITIN_HUMAN
θ value	1.81305 (rank : 45)	NC score	-0.001540 (rank : 88)
Query Neighborhood Hits	78	Target Neighborhood Hits	2923	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

FANCE_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.025897 (rank : 45)
Query Neighborhood Hits	78	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HB96, Q4ZGH2	Gene names	FANCE
Domain Architecture	No domain graphic available
Description	Fanconi anemia group E protein (Protein FACE).

FRM4B_MOUSE
θ value	2.36792 (rank : 47)	NC score	0.014005 (rank : 53)
Query Neighborhood Hits	78	Target Neighborhood Hits	109	Shared Neighborhood Hits	7
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

GCC2_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.012876 (rank : 57)
Query Neighborhood Hits	78	Target Neighborhood Hits	1558	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

MLL2_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.005242 (rank : 84)
Query Neighborhood Hits	78	Target Neighborhood Hits	1788	Shared Neighborhood Hits	18
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

RBP24_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.012908 (rank : 56)
Query Neighborhood Hits	78	Target Neighborhood Hits	1559	Shared Neighborhood Hits	27
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

TRPV1_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.146177 (rank : 28)
Query Neighborhood Hits	78	Target Neighborhood Hits	184	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

ANLN_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.013480 (rank : 55)
Query Neighborhood Hits	78	Target Neighborhood Hits	222	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

CCD91_MOUSE
θ value	3.0926 (rank : 53)	NC score	0.012053 (rank : 59)
Query Neighborhood Hits	78	Target Neighborhood Hits	699	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

DMD_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.011976 (rank : 60)
Query Neighborhood Hits	78	Target Neighborhood Hits	1135	Shared Neighborhood Hits	25
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

NMDE1_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.005264 (rank : 83)
Query Neighborhood Hits	78	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

RF1M_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.016038 (rank : 51)
Query Neighborhood Hits	78	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	O75570, Q5T6Y5, Q8IUQ6	Gene names	MTRF1
Domain Architecture
Description	Peptide chain release factor 1, mitochondrial precursor (MRF-1).

CF170_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.017309 (rank : 48)
Query Neighborhood Hits	78	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q96NH3, Q6ZMY4, Q6ZUR7, Q8NB47	Gene names	C6orf170
Domain Architecture	No domain graphic available
Description	Protein C6orf170.

MYPT1_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.007790 (rank : 75)
Query Neighborhood Hits	78	Target Neighborhood Hits	723	Shared Neighborhood Hits	21
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

MYPT1_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.011694 (rank : 62)
Query Neighborhood Hits	78	Target Neighborhood Hits	539	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

AKAP9_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.027366 (rank : 44)
Query Neighborhood Hits	78	Target Neighborhood Hits	1710	Shared Neighborhood Hits	29
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ZN142_HUMAN
θ value	5.27518 (rank : 61)	NC score	-0.002450 (rank : 89)
Query Neighborhood Hits	78	Target Neighborhood Hits	1007	Shared Neighborhood Hits	5
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

CCD46_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.006956 (rank : 76)
Query Neighborhood Hits	78	Target Neighborhood Hits	1405	Shared Neighborhood Hits	24
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CCD93_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.008195 (rank : 73)
Query Neighborhood Hits	78	Target Neighborhood Hits	362	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CENPE_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.005371 (rank : 82)
Query Neighborhood Hits	78	Target Neighborhood Hits	2060	Shared Neighborhood Hits	29
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

MTERF_MOUSE
θ value	6.88961 (rank : 65)	NC score	0.011270 (rank : 64)
Query Neighborhood Hits	78	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CHZ9, Q63ZX5, Q8C7T1	Gene names	Mterf
Domain Architecture	No domain graphic available
Description	Transcription termination factor, mitochondrial precursor (mTERF) (Mitochondrial transcription termination factor 1).

SLC2B_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.011729 (rank : 61)
Query Neighborhood Hits	78	Target Neighborhood Hits	214	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

STXB4_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.008342 (rank : 72)
Query Neighborhood Hits	78	Target Neighborhood Hits	616	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

AFF1_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.004044 (rank : 86)
Query Neighborhood Hits	78	Target Neighborhood Hits	506	Shared Neighborhood Hits	8
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

BICD1_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.005971 (rank : 80)
Query Neighborhood Hits	78	Target Neighborhood Hits	837	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CP135_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.004656 (rank : 85)
Query Neighborhood Hits	78	Target Neighborhood Hits	1290	Shared Neighborhood Hits	20
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DOS_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.011379 (rank : 63)
Query Neighborhood Hits	78	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N350, O43385	Gene names	DOS, C19orf26
Domain Architecture	No domain graphic available
Description	Protein Dos.

EDN3_MOUSE
θ value	8.99809 (rank : 72)	NC score	0.008548 (rank : 71)
Query Neighborhood Hits	78	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	P48299, Q543L0	Gene names	Edn3
Domain Architecture
Description	Endothelin-3 precursor (ET-3) (Preproendothelin-3) (PPET3).

FA8_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.003533 (rank : 87)
Query Neighborhood Hits	78	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

NCKPL_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.006299 (rank : 78)
Query Neighborhood Hits	78	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P55160	Gene names	NCKAP1L, HEM1
Domain Architecture	No domain graphic available
Description	Nck-associated protein 1-like (Membrane-associated protein HEM-1) (Hematopoietic protein 1).

PCNT_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.009014 (rank : 67)
Query Neighborhood Hits	78	Target Neighborhood Hits	1551	Shared Neighborhood Hits	22
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PF21B_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.005435 (rank : 81)
Query Neighborhood Hits	78	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PRGC2_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.005991 (rank : 79)
Query Neighborhood Hits	78	Target Neighborhood Hits	272	Shared Neighborhood Hits	3
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

WWTR1_MOUSE
θ value	8.99809 (rank : 78)	NC score	0.006862 (rank : 77)
Query Neighborhood Hits	78	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

NUD9P_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.103483 (rank : 38)
Query Neighborhood Hits	78	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N2Z3	Gene names	NUDT9P1, C10orf98
Domain Architecture	No domain graphic available
Description	Putative nucleoside diphosphate-linked moiety X motif 9P1.

NUDT9_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.136135 (rank : 33)
Query Neighborhood Hits	78	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BW91, Q8NBN1, Q8NCB9, Q8NG25	Gene names	NUDT9, NUDT10
Domain Architecture
Description	ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate- linked moiety X motif 9) (Nudix motif 9).

NUDT9_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.136933 (rank : 32)
Query Neighborhood Hits	78	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BVU5, Q3TZ68, Q8K1J4	Gene names	Nudt9
Domain Architecture	No domain graphic available
Description	ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate- linked moiety X motif 9) (Nudix motif 9).

PK2L1_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.093806 (rank : 39)
Query Neighborhood Hits	78	Target Neighborhood Hits	132	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.057296 (rank : 42)
Query Neighborhood Hits	78	Target Neighborhood Hits	90	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L2_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.069253 (rank : 41)
Query Neighborhood Hits	78	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

TRPV1_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.139831 (rank : 31)
Query Neighborhood Hits	78	Target Neighborhood Hits	189	Shared Neighborhood Hits	30
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV2_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.081510 (rank : 40)
Query Neighborhood Hits	78	Target Neighborhood Hits	130	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

TRPV2_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.105611 (rank : 37)
Query Neighborhood Hits	78	Target Neighborhood Hits	111	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TRPV4_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.133036 (rank : 35)
Query Neighborhood Hits	78	Target Neighborhood Hits	150	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.119096 (rank : 36)
Query Neighborhood Hits	78	Target Neighborhood Hits	117	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

Hits sorted by NC score

TRPM6_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	78
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM6_HUMAN
NC score	0.990346 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	78	Target Neighborhood Hits	91	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM7_MOUSE
NC score	0.978272 (rank : 3)	θ value	0 (rank : 5)
Query Neighborhood Hits	78	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TRPM7_HUMAN
NC score	0.977476 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	78	Target Neighborhood Hits	104	Shared Neighborhood Hits	35
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM3_HUMAN
NC score	0.959760 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	78	Target Neighborhood Hits	121	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TRPM2_MOUSE
NC score	0.851060 (rank : 6)	θ value	9.056e-93 (rank : 7)
Query Neighborhood Hits	78	Target Neighborhood Hits	61	Shared Neighborhood Hits	30
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPM8_HUMAN
NC score	0.848768 (rank : 7)	θ value	1.3939e-101 (rank : 6)
Query Neighborhood Hits	78	Target Neighborhood Hits	65	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

TRPM2_HUMAN
NC score	0.847341 (rank : 8)	θ value	1.44581e-90 (rank : 8)
Query Neighborhood Hits	78	Target Neighborhood Hits	64	Shared Neighborhood Hits	29
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TRPM8_MOUSE
NC score	0.843088 (rank : 9)	θ value	2.18062e-54 (rank : 9)
Query Neighborhood Hits	78	Target Neighborhood Hits	58	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TRPC4_HUMAN
NC score	0.487317 (rank : 10)	θ value	5.25075e-16 (rank : 11)
Query Neighborhood Hits	78	Target Neighborhood Hits	140	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
NC score	0.486156 (rank : 11)	θ value	4.02038e-16 (rank : 10)
Query Neighborhood Hits	78	Target Neighborhood Hits	141	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC5_MOUSE
NC score	0.470499 (rank : 12)	θ value	1.68911e-14 (rank : 13)
Query Neighborhood Hits	78	Target Neighborhood Hits	124	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC5_HUMAN
NC score	0.470178 (rank : 13)	θ value	1.68911e-14 (rank : 12)
Query Neighborhood Hits	78	Target Neighborhood Hits	122	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC2_MOUSE
NC score	0.435137 (rank : 14)	θ value	2.36244e-08 (rank : 16)
Query Neighborhood Hits	78	Target Neighborhood Hits	84	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TRPC3_MOUSE
NC score	0.405864 (rank : 15)	θ value	2.36244e-08 (rank : 17)
Query Neighborhood Hits	78	Target Neighborhood Hits	131	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC3_HUMAN
NC score	0.394975 (rank : 16)	θ value	5.81887e-07 (rank : 22)
Query Neighborhood Hits	78	Target Neighborhood Hits	137	Shared Neighborhood Hits	29
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC6_MOUSE
NC score	0.375315 (rank : 17)	θ value	2.61198e-07 (rank : 21)
Query Neighborhood Hits	78	Target Neighborhood Hits	171	Shared Neighborhood Hits	33
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC6_HUMAN
NC score	0.374651 (rank : 18)	θ value	2.61198e-07 (rank : 20)
Query Neighborhood Hits	78	Target Neighborhood Hits	171	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC7_MOUSE
NC score	0.367226 (rank : 19)	θ value	1.99992e-07 (rank : 19)
Query Neighborhood Hits	78	Target Neighborhood Hits	114	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC7_HUMAN
NC score	0.366325 (rank : 20)	θ value	1.99992e-07 (rank : 18)
Query Neighborhood Hits	78	Target Neighborhood Hits	123	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC1_MOUSE
NC score	0.346213 (rank : 21)	θ value	0.000461057 (rank : 26)
Query Neighborhood Hits	78	Target Neighborhood Hits	87	Shared Neighborhood Hits	29
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPC1_HUMAN
NC score	0.346053 (rank : 22)	θ value	0.000461057 (rank : 25)
Query Neighborhood Hits	78	Target Neighborhood Hits	91	Shared Neighborhood Hits	31
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

EF2K_MOUSE
NC score	0.343178 (rank : 23)	θ value	4.59992e-12 (rank : 14)
Query Neighborhood Hits	78	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	O08796	Gene names	Eef2k
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

EF2K_HUMAN
NC score	0.334990 (rank : 24)	θ value	5.08577e-11 (rank : 15)
Query Neighborhood Hits	78	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	O00418	Gene names	EEF2K
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

TRPV3_MOUSE
NC score	0.222551 (rank : 25)	θ value	3.19293e-05 (rank : 23)
Query Neighborhood Hits	78	Target Neighborhood Hits	188	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV3_HUMAN
NC score	0.221802 (rank : 26)	θ value	7.1131e-05 (rank : 24)
Query Neighborhood Hits	78	Target Neighborhood Hits	198	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV6_HUMAN
NC score	0.158423 (rank : 27)	θ value	0.0148317 (rank : 28)
Query Neighborhood Hits	78	Target Neighborhood Hits	262	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV1_HUMAN
NC score	0.146177 (rank : 28)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	78	Target Neighborhood Hits	184	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV6_MOUSE
NC score	0.144289 (rank : 29)	θ value	0.0252991 (rank : 29)
Query Neighborhood Hits	78	Target Neighborhood Hits	284	Shared Neighborhood Hits	31
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

TRPV5_HUMAN
NC score	0.142239 (rank : 30)	θ value	0.00869519 (rank : 27)
Query Neighborhood Hits	78	Target Neighborhood Hits	261	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV1_MOUSE
NC score	0.139831 (rank : 31)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	78	Target Neighborhood Hits	189	Shared Neighborhood Hits	30
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

NUDT9_MOUSE
NC score	0.136933 (rank : 32)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	78	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BVU5, Q3TZ68, Q8K1J4	Gene names	Nudt9
Domain Architecture	No domain graphic available
Description	ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate- linked moiety X motif 9) (Nudix motif 9).

NUDT9_HUMAN
NC score	0.136135 (rank : 33)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	78	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BW91, Q8NBN1, Q8NCB9, Q8NG25	Gene names	NUDT9, NUDT10
Domain Architecture
Description	ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate- linked moiety X motif 9) (Nudix motif 9).

TRPV5_MOUSE
NC score	0.135403 (rank : 34)	θ value	0.0563607 (rank : 30)
Query Neighborhood Hits	78	Target Neighborhood Hits	278	Shared Neighborhood Hits	30
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV4_HUMAN
NC score	0.133036 (rank : 35)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	78	Target Neighborhood Hits	150	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
NC score	0.119096 (rank : 36)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	78	Target Neighborhood Hits	117	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV2_MOUSE
NC score	0.105611 (rank : 37)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	78	Target Neighborhood Hits	111	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

NUD9P_HUMAN
NC score	0.103483 (rank : 38)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	78	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N2Z3	Gene names	NUDT9P1, C10orf98
Domain Architecture	No domain graphic available
Description	Putative nucleoside diphosphate-linked moiety X motif 9P1.

PK2L1_HUMAN
NC score	0.093806 (rank : 39)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	78	Target Neighborhood Hits	132	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

TRPV2_HUMAN
NC score	0.081510 (rank : 40)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	78	Target Neighborhood Hits	130	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

PK2L2_MOUSE
NC score	0.069253 (rank : 41)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	78	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L2_HUMAN
NC score	0.057296 (rank : 42)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	78	Target Neighborhood Hits	90	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PCNT_MOUSE
NC score	0.032488 (rank : 43)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	78	Target Neighborhood Hits	1207	Shared Neighborhood Hits	24
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

AKAP9_HUMAN
NC score	0.027366 (rank : 44)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	78	Target Neighborhood Hits	1710	Shared Neighborhood Hits	29
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

FANCE_HUMAN
NC score	0.025897 (rank : 45)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	78	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HB96, Q4ZGH2	Gene names	FANCE
Domain Architecture	No domain graphic available
Description	Fanconi anemia group E protein (Protein FACE).

CNGA1_HUMAN
NC score	0.023862 (rank : 46)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	78	Target Neighborhood Hits	149	Shared Neighborhood Hits	5
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
NC score	0.020231 (rank : 47)	θ value	0.0961366 (rank : 31)
Query Neighborhood Hits	78	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CF170_HUMAN
NC score	0.017309 (rank : 48)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	78	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q96NH3, Q6ZMY4, Q6ZUR7, Q8NB47	Gene names	C6orf170
Domain Architecture	No domain graphic available
Description	Protein C6orf170.

FRM4B_HUMAN
NC score	0.016908 (rank : 49)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	78	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

UBP37_HUMAN
NC score	0.016825 (rank : 50)	θ value	0.365318 (rank : 33)
Query Neighborhood Hits	78	Target Neighborhood Hits	208	Shared Neighborhood Hits	7
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

RF1M_HUMAN
NC score	0.016038 (rank : 51)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	78	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	O75570, Q5T6Y5, Q8IUQ6	Gene names	MTRF1
Domain Architecture
Description	Peptide chain release factor 1, mitochondrial precursor (MRF-1).

SYNE1_HUMAN
NC score	0.015445 (rank : 52)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	78	Target Neighborhood Hits	1484	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

FRM4B_MOUSE
NC score	0.014005 (rank : 53)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	78	Target Neighborhood Hits	109	Shared Neighborhood Hits	7
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

INP4A_MOUSE
NC score	0.013718 (rank : 54)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	78	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPW0, Q8CBJ8	Gene names	Inpp4a
Domain Architecture	No domain graphic available
Description	Type I inositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type I).

ANLN_HUMAN
NC score	0.013480 (rank : 55)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	78	Target Neighborhood Hits	222	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

RBP24_HUMAN
NC score	0.012908 (rank : 56)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	78	Target Neighborhood Hits	1559	Shared Neighborhood Hits	27
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.012876 (rank : 57)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	78	Target Neighborhood Hits	1558	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

SYCP1_MOUSE
NC score	0.012409 (rank : 58)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	78	Target Neighborhood Hits	1456	Shared Neighborhood Hits	26
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CCD91_MOUSE
NC score	0.012053 (rank : 59)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	78	Target Neighborhood Hits	699	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

DMD_HUMAN
NC score	0.011976 (rank : 60)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	78	Target Neighborhood Hits	1135	Shared Neighborhood Hits	25
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

SLC2B_HUMAN
NC score	0.011729 (rank : 61)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	78	Target Neighborhood Hits	214	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

MYPT1_MOUSE
NC score	0.011694 (rank : 62)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	78	Target Neighborhood Hits	539	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

DOS_HUMAN
NC score	0.011379 (rank : 63)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	78	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N350, O43385	Gene names	DOS, C19orf26
Domain Architecture	No domain graphic available
Description	Protein Dos.

MTERF_MOUSE
NC score	0.011270 (rank : 64)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	78	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CHZ9, Q63ZX5, Q8C7T1	Gene names	Mterf
Domain Architecture	No domain graphic available
Description	Transcription termination factor, mitochondrial precursor (mTERF) (Mitochondrial transcription termination factor 1).

DMD_MOUSE
NC score	0.010958 (rank : 65)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	78	Target Neighborhood Hits	1111	Shared Neighborhood Hits	25
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

LRSM1_HUMAN
NC score	0.010371 (rank : 66)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	78	Target Neighborhood Hits	1078	Shared Neighborhood Hits	22
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

PCNT_HUMAN
NC score	0.009014 (rank : 67)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	78	Target Neighborhood Hits	1551	Shared Neighborhood Hits	22
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

CBPB2_MOUSE
NC score	0.009012 (rank : 68)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	78	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHH6, Q5EBI3, Q9QZF0	Gene names	Cpb2, Tafi
Domain Architecture	No domain graphic available
Description	Carboxypeptidase B2 precursor (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) (Carboxypeptidase R) (CPR).

CSPG2_HUMAN
NC score	0.008680 (rank : 69)	θ value	0.279714 (rank : 32)
Query Neighborhood Hits	78	Target Neighborhood Hits	681	Shared Neighborhood Hits	4
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

NUCL_MOUSE
NC score	0.008629 (rank : 70)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	78	Target Neighborhood Hits	425	Shared Neighborhood Hits	5
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

EDN3_MOUSE
NC score	0.008548 (rank : 71)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	78	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	P48299, Q543L0	Gene names	Edn3
Domain Architecture
Description	Endothelin-3 precursor (ET-3) (Preproendothelin-3) (PPET3).

STXB4_HUMAN
NC score	0.008342 (rank : 72)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	78	Target Neighborhood Hits	616	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZWJ1, Q8IVZ5	Gene names	STXBP4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

CCD93_MOUSE
NC score	0.008195 (rank : 73)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	78	Target Neighborhood Hits	362	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TQK5, Q3TX53	Gene names	Ccdc93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

COHA1_HUMAN
NC score	0.008120 (rank : 74)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	78	Target Neighborhood Hits	400	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

MYPT1_HUMAN
NC score	0.007790 (rank : 75)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	78	Target Neighborhood Hits	723	Shared Neighborhood Hits	21
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

CCD46_MOUSE
NC score	0.006956 (rank : 76)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	78	Target Neighborhood Hits	1405	Shared Neighborhood Hits	24
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

WWTR1_MOUSE
NC score	0.006862 (rank : 77)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	78	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPK5, Q99KI4	Gene names	Wwtr1, Taz
Domain Architecture	No domain graphic available
Description	WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif).

NCKPL_HUMAN
NC score	0.006299 (rank : 78)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	78	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P55160	Gene names	NCKAP1L, HEM1
Domain Architecture	No domain graphic available
Description	Nck-associated protein 1-like (Membrane-associated protein HEM-1) (Hematopoietic protein 1).

PRGC2_HUMAN
NC score	0.005991 (rank : 79)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	78	Target Neighborhood Hits	272	Shared Neighborhood Hits	3
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

BICD1_MOUSE
NC score	0.005971 (rank : 80)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	78	Target Neighborhood Hits	837	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

PF21B_HUMAN
NC score	0.005435 (rank : 81)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	78	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

CENPE_HUMAN
NC score	0.005371 (rank : 82)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	78	Target Neighborhood Hits	2060	Shared Neighborhood Hits	29
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

NMDE1_HUMAN
NC score	0.005264 (rank : 83)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	78	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

MLL2_HUMAN
NC score	0.005242 (rank : 84)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	78	Target Neighborhood Hits	1788	Shared Neighborhood Hits	18
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CP135_HUMAN
NC score	0.004656 (rank : 85)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	78	Target Neighborhood Hits	1290	Shared Neighborhood Hits	20
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

AFF1_HUMAN
NC score	0.004044 (rank : 86)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	78	Target Neighborhood Hits	506	Shared Neighborhood Hits	8
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

FA8_MOUSE
NC score	0.003533 (rank : 87)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	78	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

TITIN_HUMAN
NC score	-0.001540 (rank : 88)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	78	Target Neighborhood Hits	2923	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZN142_HUMAN
NC score	-0.002450 (rank : 89)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	78	Target Neighborhood Hits	1007	Shared Neighborhood Hits	5
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).