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Network neighborhood for query Sequence : REXO4_MOUSE

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REXO4_MOUSE
SwissProt Accessions	Q6PAQ4, Q3UU17, Q8C524	Gene names	Rexo4, Gm111, Pmc2, Xpmc2h
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

REXO4_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PAQ4, Q3UU17, Q8C524	Gene names	Rexo4, Gm111, Pmc2, Xpmc2h
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein homolog).

REXO4_HUMAN
θ value	4.15819e-130 (rank : 2)	NC score	0.978008 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZR2, Q5T8S4, Q5T8S5, Q5T8S6, Q9GZW3	Gene names	REXO4, PMC2, XPMC2H
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (hPMC2) (Prevents mitotic catastrophe 2 protein homolog).

I20L2_HUMAN
θ value	3.27365e-34 (rank : 3)	NC score	0.841101 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H9L3, Q64KA2	Gene names	ISG20L2
Domain Architecture
Description	Interferon-stimulated 20 kDa exonuclease-like 2 (EC 3.1.-.-).

ISG20_HUMAN
θ value	2.87452e-22 (rank : 4)	NC score	0.822907 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q96AZ6, O00441, O00586	Gene names	ISG20, HEM45
Domain Architecture	No domain graphic available
Description	Interferon-stimulated gene 20 kDa protein (EC 3.1.13.1) (Promyelocytic leukemia nuclear body-associated protein ISG20) (Estrogen-regulated transcript 45 protein).

ISG20_MOUSE
θ value	3.17815e-21 (rank : 5)	NC score	0.784534 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JL16, Q9CPZ5	Gene names	Isg20
Domain Architecture	No domain graphic available
Description	Interferon-stimulated gene 20 kDa protein (EC 3.1.13.1) (Promyelocytic leukemia nuclear body-associated protein ISG20) (DnaQL protein).

REXO1_MOUSE
θ value	6.87365e-08 (rank : 6)	NC score	0.427867 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	166	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

GOR_HUMAN
θ value	4.45536e-07 (rank : 7)	NC score	0.488416 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IX06, O95107	Gene names	REXO1L1, GOR
Domain Architecture
Description	Exonuclease GOR (EC 3.1.-.-) (Antigen GOR) (RNA exonuclease 1 homolog- like).

REXO1_HUMAN
θ value	7.59969e-07 (rank : 8)	NC score	0.404609 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	242	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

ICAL_MOUSE
θ value	0.0431538 (rank : 9)	NC score	0.074839 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	178	Shared Neighborhood Hits	7
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

SFRS4_HUMAN
θ value	0.163984 (rank : 10)	NC score	0.033950 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	384	Shared Neighborhood Hits	11
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

K1543_MOUSE
θ value	0.47712 (rank : 11)	NC score	0.042356 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	497	Shared Neighborhood Hits	9
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

DHX36_MOUSE
θ value	0.813845 (rank : 12)	NC score	0.017803 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	114	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

SAKS1_HUMAN
θ value	1.06291 (rank : 13)	NC score	0.035348 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	202	Shared Neighborhood Hits	3
SwissProt Accessions	Q04323, Q9BV93, Q9BVV5	Gene names	SAKS1
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein).

NFH_MOUSE
θ value	1.38821 (rank : 14)	NC score	0.022514 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	2247	Shared Neighborhood Hits	28
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PHF20_MOUSE
θ value	1.38821 (rank : 15)	NC score	0.033439 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	513	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PMS2_HUMAN
θ value	1.38821 (rank : 16)	NC score	0.030792 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

JIP4_HUMAN
θ value	1.81305 (rank : 17)	NC score	0.028493 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	585	Shared Neighborhood Hits	5
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

FRM4B_MOUSE
θ value	2.36792 (rank : 18)	NC score	0.014437 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

KCD18_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.027123 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

ZCH11_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.029548 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	278	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

CHD4_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.009346 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	365	Shared Neighborhood Hits	4
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

JIP4_MOUSE
θ value	3.0926 (rank : 22)	NC score	0.027620 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	593	Shared Neighborhood Hits	7
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

LYRIC_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.027794 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UE4, Q6PK07, Q8TCX3	Gene names	MTDH, AEG1, LYRIC
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/lyric) (Metastasis adhesion protein) (Metadherin) (Astrocyte elevated gene-1 protein) (AEG-1).

TCOF_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.026321 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	543	Shared Neighborhood Hits	14
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TR150_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.021821 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	468	Shared Neighborhood Hits	12
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

ATBF1_MOUSE
θ value	5.27518 (rank : 26)	NC score	0.006423 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	1841	Shared Neighborhood Hits	14
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CSKI1_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.006819 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	997	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CT043_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.023912 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q99K95, Q543D3, Q80X88, Q9CV27	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf43 homolog.

POPD1_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.039253 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ES83, Q8C8L3	Gene names	Bves, Pop1, Popdc1
Domain Architecture
Description	Blood vessel epicardial substance (Popeye domain-containing protein 1) (Popeye protein 1).

C8AP2_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.017624 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	405	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CIR_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.019149 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	249	Shared Neighborhood Hits	7
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

DLGP4_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.013297 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

JARD2_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.015103 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	169	Shared Neighborhood Hits	7
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

LAMA4_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.005038 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	584	Shared Neighborhood Hits	2
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

SFPQ_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.014847 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	986	Shared Neighborhood Hits	12
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFPQ_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.014700 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	958	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

AFF2_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.016363 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	218	Shared Neighborhood Hits	10
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

BAT2_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.018729 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	947	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCR_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.007689 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	204	Shared Neighborhood Hits	6
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

MYO9B_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.004072 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	311	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

PCLO_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.014957 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	2046	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SYNJ2_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.008447 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

Hits sorted by NC score

REXO4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PAQ4, Q3UU17, Q8C524	Gene names	Rexo4, Gm111, Pmc2, Xpmc2h
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein homolog).

REXO4_HUMAN
NC score	0.978008 (rank : 2)	θ value	4.15819e-130 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZR2, Q5T8S4, Q5T8S5, Q5T8S6, Q9GZW3	Gene names	REXO4, PMC2, XPMC2H
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (hPMC2) (Prevents mitotic catastrophe 2 protein homolog).

I20L2_HUMAN
NC score	0.841101 (rank : 3)	θ value	3.27365e-34 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H9L3, Q64KA2	Gene names	ISG20L2
Domain Architecture
Description	Interferon-stimulated 20 kDa exonuclease-like 2 (EC 3.1.-.-).

ISG20_HUMAN
NC score	0.822907 (rank : 4)	θ value	2.87452e-22 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q96AZ6, O00441, O00586	Gene names	ISG20, HEM45
Domain Architecture	No domain graphic available
Description	Interferon-stimulated gene 20 kDa protein (EC 3.1.13.1) (Promyelocytic leukemia nuclear body-associated protein ISG20) (Estrogen-regulated transcript 45 protein).

ISG20_MOUSE
NC score	0.784534 (rank : 5)	θ value	3.17815e-21 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JL16, Q9CPZ5	Gene names	Isg20
Domain Architecture	No domain graphic available
Description	Interferon-stimulated gene 20 kDa protein (EC 3.1.13.1) (Promyelocytic leukemia nuclear body-associated protein ISG20) (DnaQL protein).

GOR_HUMAN
NC score	0.488416 (rank : 6)	θ value	4.45536e-07 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IX06, O95107	Gene names	REXO1L1, GOR
Domain Architecture
Description	Exonuclease GOR (EC 3.1.-.-) (Antigen GOR) (RNA exonuclease 1 homolog- like).

REXO1_MOUSE
NC score	0.427867 (rank : 7)	θ value	6.87365e-08 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	166	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

REXO1_HUMAN
NC score	0.404609 (rank : 8)	θ value	7.59969e-07 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	242	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

ICAL_MOUSE
NC score	0.074839 (rank : 9)	θ value	0.0431538 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	178	Shared Neighborhood Hits	7
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

K1543_MOUSE
NC score	0.042356 (rank : 10)	θ value	0.47712 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	497	Shared Neighborhood Hits	9
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

POPD1_MOUSE
NC score	0.039253 (rank : 11)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ES83, Q8C8L3	Gene names	Bves, Pop1, Popdc1
Domain Architecture
Description	Blood vessel epicardial substance (Popeye domain-containing protein 1) (Popeye protein 1).

SAKS1_HUMAN
NC score	0.035348 (rank : 12)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	202	Shared Neighborhood Hits	3
SwissProt Accessions	Q04323, Q9BV93, Q9BVV5	Gene names	SAKS1
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein).

SFRS4_HUMAN
NC score	0.033950 (rank : 13)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	384	Shared Neighborhood Hits	11
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

PHF20_MOUSE
NC score	0.033439 (rank : 14)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	513	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PMS2_HUMAN
NC score	0.030792 (rank : 15)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

ZCH11_HUMAN
NC score	0.029548 (rank : 16)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	278	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

JIP4_HUMAN
NC score	0.028493 (rank : 17)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	585	Shared Neighborhood Hits	5
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

LYRIC_HUMAN
NC score	0.027794 (rank : 18)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UE4, Q6PK07, Q8TCX3	Gene names	MTDH, AEG1, LYRIC
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/lyric) (Metastasis adhesion protein) (Metadherin) (Astrocyte elevated gene-1 protein) (AEG-1).

JIP4_MOUSE
NC score	0.027620 (rank : 19)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	593	Shared Neighborhood Hits	7
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

KCD18_HUMAN
NC score	0.027123 (rank : 20)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

TCOF_HUMAN
NC score	0.026321 (rank : 21)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	543	Shared Neighborhood Hits	14
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CT043_MOUSE
NC score	0.023912 (rank : 22)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q99K95, Q543D3, Q80X88, Q9CV27	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf43 homolog.

NFH_MOUSE
NC score	0.022514 (rank : 23)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	2247	Shared Neighborhood Hits	28
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TR150_MOUSE
NC score	0.021821 (rank : 24)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	468	Shared Neighborhood Hits	12
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

CIR_HUMAN
NC score	0.019149 (rank : 25)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	249	Shared Neighborhood Hits	7
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

BAT2_MOUSE
NC score	0.018729 (rank : 26)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	947	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DHX36_MOUSE
NC score	0.017803 (rank : 27)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	114	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

C8AP2_MOUSE
NC score	0.017624 (rank : 28)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	405	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

AFF2_HUMAN
NC score	0.016363 (rank : 29)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	218	Shared Neighborhood Hits	10
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

JARD2_MOUSE
NC score	0.015103 (rank : 30)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	169	Shared Neighborhood Hits	7
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

PCLO_HUMAN
NC score	0.014957 (rank : 31)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	2046	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SFPQ_HUMAN
NC score	0.014847 (rank : 32)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	986	Shared Neighborhood Hits	12
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFPQ_MOUSE
NC score	0.014700 (rank : 33)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	958	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

FRM4B_MOUSE
NC score	0.014437 (rank : 34)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

DLGP4_HUMAN
NC score	0.013297 (rank : 35)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

CHD4_HUMAN
NC score	0.009346 (rank : 36)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	365	Shared Neighborhood Hits	4
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

SYNJ2_HUMAN
NC score	0.008447 (rank : 37)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

BCR_HUMAN
NC score	0.007689 (rank : 38)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	204	Shared Neighborhood Hits	6
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CSKI1_HUMAN
NC score	0.006819 (rank : 39)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	997	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ATBF1_MOUSE
NC score	0.006423 (rank : 40)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	1841	Shared Neighborhood Hits	14
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

LAMA4_MOUSE
NC score	0.005038 (rank : 41)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	584	Shared Neighborhood Hits	2
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MYO9B_MOUSE
NC score	0.004072 (rank : 42)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	311	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).