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Network neighborhood for query Sequence : DHX36_MOUSE

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DHX36_MOUSE
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DHX36_HUMAN
θ value	0 (rank : 1)	NC score	0.994097 (rank : 2)
Query Neighborhood Hits	114	Target Neighborhood Hits	63	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX36_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	114
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX57_HUMAN
θ value	6.54689e-176 (rank : 3)	NC score	0.960686 (rank : 7)
Query Neighborhood Hits	114	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX57_MOUSE
θ value	1.15563e-172 (rank : 4)	NC score	0.962172 (rank : 5)
Query Neighborhood Hits	114	Target Neighborhood Hits	125	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX29_HUMAN
θ value	1.6163e-166 (rank : 5)	NC score	0.959894 (rank : 8)
Query Neighborhood Hits	114	Target Neighborhood Hits	144	Shared Neighborhood Hits	38
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

DHX29_MOUSE
θ value	8.02161e-166 (rank : 6)	NC score	0.962081 (rank : 6)
Query Neighborhood Hits	114	Target Neighborhood Hits	103	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PGC1, Q8BQJ4, Q8BT01, Q8C9B7, Q8C9H9	Gene names	Dhx29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29).

DHX9_HUMAN
θ value	5.9766e-145 (rank : 7)	NC score	0.965279 (rank : 3)
Query Neighborhood Hits	114	Target Neighborhood Hits	62	Shared Neighborhood Hits	29
SwissProt Accessions	Q08211, Q5VY62, Q6PD69, Q99556	Gene names	DHX9, DDX9, NDH2
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9).

DHX9_MOUSE
θ value	3.62588e-142 (rank : 8)	NC score	0.962982 (rank : 4)
Query Neighborhood Hits	114	Target Neighborhood Hits	72	Shared Neighborhood Hits	27
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

DHX30_HUMAN
θ value	1.09172e-138 (rank : 9)	NC score	0.957159 (rank : 9)
Query Neighborhood Hits	114	Target Neighborhood Hits	43	Shared Neighborhood Hits	25
SwissProt Accessions	Q7L2E3, O94965, Q7Z753, Q96CH4	Gene names	DHX30, KIAA0890
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX30_MOUSE
θ value	2.97304e-136 (rank : 10)	NC score	0.956653 (rank : 10)
Query Neighborhood Hits	114	Target Neighborhood Hits	45	Shared Neighborhood Hits	26
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX34_MOUSE
θ value	2.54619e-95 (rank : 11)	NC score	0.927727 (rank : 11)
Query Neighborhood Hits	114	Target Neighborhood Hits	235	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DBV3	Gene names	Dhx34, Ddx34, Kiaa0134
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX8_HUMAN
θ value	7.93343e-89 (rank : 12)	NC score	0.908000 (rank : 18)
Query Neighborhood Hits	114	Target Neighborhood Hits	86	Shared Neighborhood Hits	29
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

DHX15_HUMAN
θ value	5.32145e-85 (rank : 13)	NC score	0.921505 (rank : 13)
Query Neighborhood Hits	114	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	O43143, Q9NQT7	Gene names	DHX15, DBP1, DDX15
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15) (ATP-dependent RNA helicase #46).

DHX15_MOUSE
θ value	5.32145e-85 (rank : 14)	NC score	0.921333 (rank : 14)
Query Neighborhood Hits	114	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	O35286, Q99L91	Gene names	Dhx15, Ddx15, Deah9
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15).

DHX35_HUMAN
θ value	6.30065e-78 (rank : 15)	NC score	0.920299 (rank : 15)
Query Neighborhood Hits	114	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H5Z1, Q5THR0, Q9H4H7, Q9H6T6	Gene names	DHX35, C20orf15, DDX35
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX35 (EC 3.6.1.-) (DEAH box protein 35).

DHX40_MOUSE
θ value	6.52014e-75 (rank : 16)	NC score	0.910523 (rank : 17)
Query Neighborhood Hits	114	Target Neighborhood Hits	40	Shared Neighborhood Hits	29
SwissProt Accessions	Q6PE54, Q8BPH2, Q8CD88, Q9CWN3	Gene names	Dhx40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40).

DHX40_HUMAN
θ value	1.45253e-74 (rank : 17)	NC score	0.911173 (rank : 16)
Query Neighborhood Hits	114	Target Neighborhood Hits	34	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IX18, Q5JPH4, Q8TC86, Q8WY53, Q9BXM1, Q9H6M9	Gene names	DHX40, DDX40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40) (ARG147) (Protein PAD).

DHX37_HUMAN
θ value	7.47731e-63 (rank : 18)	NC score	0.906958 (rank : 19)
Query Neighborhood Hits	114	Target Neighborhood Hits	133	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

PRP16_HUMAN
θ value	2.65945e-60 (rank : 19)	NC score	0.903714 (rank : 20)
Query Neighborhood Hits	114	Target Neighborhood Hits	135	Shared Neighborhood Hits	30
SwissProt Accessions	Q92620, O75212, Q96HN7	Gene names	DHX38, DDX38, KIAA0224, PRP16
Domain Architecture
Description	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.1.-) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38).

DHX16_HUMAN
θ value	7.25919e-50 (rank : 20)	NC score	0.870657 (rank : 23)
Query Neighborhood Hits	114	Target Neighborhood Hits	356	Shared Neighborhood Hits	50
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

YTDC2_HUMAN
θ value	2.3352e-48 (rank : 21)	NC score	0.853913 (rank : 24)
Query Neighborhood Hits	114	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H6S0	Gene names	YTHDC2
Domain Architecture	No domain graphic available
Description	YTH domain-containing protein 2.

DHX34_HUMAN
θ value	1.73182e-43 (rank : 22)	NC score	0.926410 (rank : 12)
Query Neighborhood Hits	114	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	Q14147	Gene names	DHX34, DDX34, KIAA0134
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX33_MOUSE
θ value	2.76489e-41 (rank : 23)	NC score	0.902339 (rank : 21)
Query Neighborhood Hits	114	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	Q80VY9, Q8BS50	Gene names	Dhx33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

DHX33_HUMAN
θ value	4.71619e-41 (rank : 24)	NC score	0.896492 (rank : 22)
Query Neighborhood Hits	114	Target Neighborhood Hits	40	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H6R0, Q4G149, Q5CZ73, Q9H5M9	Gene names	DHX33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

TTF1_HUMAN
θ value	0.0193708 (rank : 25)	NC score	0.041637 (rank : 33)
Query Neighborhood Hits	114	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	Q15361, Q4VXF3, Q58EY2, Q6P5T5	Gene names	TTF1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (RNA polymerase I termination factor).

SK2L2_MOUSE
θ value	0.0252991 (rank : 26)	NC score	0.051944 (rank : 27)
Query Neighborhood Hits	114	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

STIM1_HUMAN
θ value	0.0330416 (rank : 27)	NC score	0.042223 (rank : 32)
Query Neighborhood Hits	114	Target Neighborhood Hits	665	Shared Neighborhood Hits	43
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

DDX47_HUMAN
θ value	0.0431538 (rank : 28)	NC score	0.030535 (rank : 41)
Query Neighborhood Hits	114	Target Neighborhood Hits	97	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
θ value	0.0431538 (rank : 29)	NC score	0.031185 (rank : 39)
Query Neighborhood Hits	114	Target Neighborhood Hits	97	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX49_HUMAN
θ value	0.0431538 (rank : 30)	NC score	0.041497 (rank : 34)
Query Neighborhood Hits	114	Target Neighborhood Hits	223	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

STIM1_MOUSE
θ value	0.0563607 (rank : 31)	NC score	0.042766 (rank : 31)
Query Neighborhood Hits	114	Target Neighborhood Hits	660	Shared Neighborhood Hits	43
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

RENT2_HUMAN
θ value	0.0736092 (rank : 32)	NC score	0.037011 (rank : 35)
Query Neighborhood Hits	114	Target Neighborhood Hits	618	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

SK2L2_HUMAN
θ value	0.0736092 (rank : 33)	NC score	0.049904 (rank : 28)
Query Neighborhood Hits	114	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

AKAP9_HUMAN
θ value	0.0961366 (rank : 34)	NC score	0.020683 (rank : 58)
Query Neighborhood Hits	114	Target Neighborhood Hits	1710	Shared Neighborhood Hits	46
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

TRHY_HUMAN
θ value	0.125558 (rank : 35)	NC score	0.024854 (rank : 48)
Query Neighborhood Hits	114	Target Neighborhood Hits	1385	Shared Neighborhood Hits	47
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

DDX50_HUMAN
θ value	0.163984 (rank : 36)	NC score	0.046750 (rank : 29)
Query Neighborhood Hits	114	Target Neighborhood Hits	132	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

SMBP2_HUMAN
θ value	0.163984 (rank : 37)	NC score	0.058528 (rank : 25)
Query Neighborhood Hits	114	Target Neighborhood Hits	107	Shared Neighborhood Hits	14
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

MYO6_HUMAN
θ value	0.21417 (rank : 38)	NC score	0.016311 (rank : 67)
Query Neighborhood Hits	114	Target Neighborhood Hits	727	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

PLEC1_HUMAN
θ value	0.21417 (rank : 39)	NC score	0.016115 (rank : 70)
Query Neighborhood Hits	114	Target Neighborhood Hits	1326	Shared Neighborhood Hits	42
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

CENPF_HUMAN
θ value	0.279714 (rank : 40)	NC score	0.018909 (rank : 61)
Query Neighborhood Hits	114	Target Neighborhood Hits	1932	Shared Neighborhood Hits	50
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

DDX49_MOUSE
θ value	0.279714 (rank : 41)	NC score	0.036942 (rank : 36)
Query Neighborhood Hits	114	Target Neighborhood Hits	119	Shared Neighborhood Hits	18
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

SNX23_HUMAN
θ value	0.279714 (rank : 42)	NC score	0.012963 (rank : 84)
Query Neighborhood Hits	114	Target Neighborhood Hits	944	Shared Neighborhood Hits	37
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

ZC313_HUMAN
θ value	0.279714 (rank : 43)	NC score	0.033472 (rank : 37)
Query Neighborhood Hits	114	Target Neighborhood Hits	772	Shared Neighborhood Hits	38
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

SMBP2_MOUSE
θ value	0.365318 (rank : 44)	NC score	0.054623 (rank : 26)
Query Neighborhood Hits	114	Target Neighborhood Hits	104	Shared Neighborhood Hits	11
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

FOLC_MOUSE
θ value	0.47712 (rank : 45)	NC score	0.021883 (rank : 56)
Query Neighborhood Hits	114	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P48760	Gene names	Fpgs
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).

GOGB1_HUMAN
θ value	0.47712 (rank : 46)	NC score	0.020621 (rank : 59)
Query Neighborhood Hits	114	Target Neighborhood Hits	2297	Shared Neighborhood Hits	57
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MD1L1_HUMAN
θ value	0.47712 (rank : 47)	NC score	0.022742 (rank : 50)
Query Neighborhood Hits	114	Target Neighborhood Hits	893	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

TPR_HUMAN
θ value	0.47712 (rank : 48)	NC score	0.022042 (rank : 55)
Query Neighborhood Hits	114	Target Neighborhood Hits	1921	Shared Neighborhood Hits	55
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CAF1A_MOUSE
θ value	0.62314 (rank : 49)	NC score	0.025777 (rank : 45)
Query Neighborhood Hits	114	Target Neighborhood Hits	736	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CTRO_MOUSE
θ value	0.62314 (rank : 50)	NC score	0.007328 (rank : 97)
Query Neighborhood Hits	114	Target Neighborhood Hits	2344	Shared Neighborhood Hits	55
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

INVO_HUMAN
θ value	0.62314 (rank : 51)	NC score	0.020061 (rank : 60)
Query Neighborhood Hits	114	Target Neighborhood Hits	636	Shared Neighborhood Hits	28
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

T2FA_HUMAN
θ value	0.62314 (rank : 52)	NC score	0.022640 (rank : 51)
Query Neighborhood Hits	114	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

DEN2A_MOUSE
θ value	0.813845 (rank : 53)	NC score	0.012028 (rank : 87)
Query Neighborhood Hits	114	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

MAP1A_HUMAN
θ value	0.813845 (rank : 54)	NC score	0.029738 (rank : 42)
Query Neighborhood Hits	114	Target Neighborhood Hits	1626	Shared Neighborhood Hits	49
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

REXO4_MOUSE
θ value	0.813845 (rank : 55)	NC score	0.017803 (rank : 63)
Query Neighborhood Hits	114	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PAQ4, Q3UU17, Q8C524	Gene names	Rexo4, Gm111, Pmc2, Xpmc2h
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein homolog).

SWP70_HUMAN
θ value	0.813845 (rank : 56)	NC score	0.016186 (rank : 69)
Query Neighborhood Hits	114	Target Neighborhood Hits	973	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

ZBT11_HUMAN
θ value	0.813845 (rank : 57)	NC score	-0.002936 (rank : 114)
Query Neighborhood Hits	114	Target Neighborhood Hits	873	Shared Neighborhood Hits	5
SwissProt Accessions	O95625	Gene names	ZBTB11
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 11.

ASPM_HUMAN
θ value	1.06291 (rank : 58)	NC score	0.018360 (rank : 62)
Query Neighborhood Hits	114	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZT6, Q86UX4, Q8IUL2, Q8IZJ7, Q8IZJ8, Q8IZJ9, Q8N4D1, Q9NVS1, Q9NVT6	Gene names	ASPM, MCPH5
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog).

BAZ2B_HUMAN
θ value	1.06291 (rank : 59)	NC score	0.013111 (rank : 82)
Query Neighborhood Hits	114	Target Neighborhood Hits	803	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

MY18B_HUMAN
θ value	1.06291 (rank : 60)	NC score	0.016689 (rank : 64)
Query Neighborhood Hits	114	Target Neighborhood Hits	1299	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH2_HUMAN
θ value	1.06291 (rank : 61)	NC score	0.014773 (rank : 76)
Query Neighborhood Hits	114	Target Neighborhood Hits	1491	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH8_HUMAN
θ value	1.06291 (rank : 62)	NC score	0.015819 (rank : 72)
Query Neighborhood Hits	114	Target Neighborhood Hits	1610	Shared Neighborhood Hits	53
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

DDX10_MOUSE
θ value	1.38821 (rank : 63)	NC score	0.027957 (rank : 43)
Query Neighborhood Hits	114	Target Neighborhood Hits	233	Shared Neighborhood Hits	23
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

SEM3D_HUMAN
θ value	1.38821 (rank : 64)	NC score	0.005820 (rank : 105)
Query Neighborhood Hits	114	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	O95025, Q6UW77, Q8NCQ1	Gene names	SEMA3D
Domain Architecture
Description	Semaphorin-3D precursor.

ITSN2_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.010413 (rank : 90)
Query Neighborhood Hits	114	Target Neighborhood Hits	1173	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

MYH8_MOUSE
θ value	1.81305 (rank : 66)	NC score	0.015830 (rank : 71)
Query Neighborhood Hits	114	Target Neighborhood Hits	1600	Shared Neighborhood Hits	53
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

BRCA1_MOUSE
θ value	2.36792 (rank : 67)	NC score	0.012456 (rank : 85)
Query Neighborhood Hits	114	Target Neighborhood Hits	436	Shared Neighborhood Hits	9
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

MACOI_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.022604 (rank : 52)
Query Neighborhood Hits	114	Target Neighborhood Hits	650	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

MACOI_MOUSE
θ value	2.36792 (rank : 69)	NC score	0.022297 (rank : 54)
Query Neighborhood Hits	114	Target Neighborhood Hits	620	Shared Neighborhood Hits	36
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

LAMC1_MOUSE
θ value	3.0926 (rank : 70)	NC score	0.005103 (rank : 107)
Query Neighborhood Hits	114	Target Neighborhood Hits	856	Shared Neighborhood Hits	27
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

TRAP1_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.013019 (rank : 83)
Query Neighborhood Hits	114	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q12931, O43642, O75235, Q9UHL5	Gene names	TRAP1, HSP75
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

DDX31_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.025776 (rank : 46)
Query Neighborhood Hits	114	Target Neighborhood Hits	132	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX50_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.043357 (rank : 30)
Query Neighborhood Hits	114	Target Neighborhood Hits	137	Shared Neighborhood Hits	25
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DYXC1_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.014161 (rank : 80)
Query Neighborhood Hits	114	Target Neighborhood Hits	261	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

GOGA4_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.021381 (rank : 57)
Query Neighborhood Hits	114	Target Neighborhood Hits	1939	Shared Neighborhood Hits	58
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GOGA6_HUMAN
θ value	4.03905 (rank : 76)	NC score	0.015669 (rank : 74)
Query Neighborhood Hits	114	Target Neighborhood Hits	1007	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

ITSN1_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.014596 (rank : 78)
Query Neighborhood Hits	114	Target Neighborhood Hits	1757	Shared Neighborhood Hits	52
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN2_MOUSE
θ value	4.03905 (rank : 78)	NC score	0.011995 (rank : 88)
Query Neighborhood Hits	114	Target Neighborhood Hits	1371	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

SEM3D_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.004861 (rank : 108)
Query Neighborhood Hits	114	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BH34	Gene names	Sema3d
Domain Architecture	No domain graphic available
Description	Semaphorin-3D precursor.

CENPE_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.016356 (rank : 66)
Query Neighborhood Hits	114	Target Neighborhood Hits	2060	Shared Neighborhood Hits	55
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

DDX21_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.030842 (rank : 40)
Query Neighborhood Hits	114	Target Neighborhood Hits	350	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

MAP9_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.010375 (rank : 91)
Query Neighborhood Hits	114	Target Neighborhood Hits	518	Shared Neighborhood Hits	21
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

PEO1_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.031655 (rank : 38)
Query Neighborhood Hits	114	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CIW5, Q8K1Z1	Gene names	Peo1
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein homolog).

PEX26_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.016653 (rank : 65)
Query Neighborhood Hits	114	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z412, Q7Z413, Q7Z414, Q7Z415, Q7Z416, Q96B12, Q9NWQ0, Q9NXU0	Gene names	PEX26
Domain Architecture
Description	Peroxisome assembly protein 26 (Peroxin-26).

SCN2A_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.003337 (rank : 111)
Query Neighborhood Hits	114	Target Neighborhood Hits	157	Shared Neighborhood Hits	7
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SMCA2_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.006592 (rank : 100)
Query Neighborhood Hits	114	Target Neighborhood Hits	503	Shared Neighborhood Hits	18
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.006206 (rank : 101)
Query Neighborhood Hits	114	Target Neighborhood Hits	597	Shared Neighborhood Hits	19
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

CAC1E_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.005912 (rank : 103)
Query Neighborhood Hits	114	Target Neighborhood Hits	148	Shared Neighborhood Hits	6
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.005854 (rank : 104)
Query Neighborhood Hits	114	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CHD8_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.003925 (rank : 109)
Query Neighborhood Hits	114	Target Neighborhood Hits	235	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CK5P2_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.016239 (rank : 68)
Query Neighborhood Hits	114	Target Neighborhood Hits	1433	Shared Neighborhood Hits	50
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

FGD3_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.003383 (rank : 110)
Query Neighborhood Hits	114	Target Neighborhood Hits	249	Shared Neighborhood Hits	6
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

G45IP_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.014712 (rank : 77)
Query Neighborhood Hits	114	Target Neighborhood Hits	118	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TAE8, Q8IVM3, Q8TE51, Q969P9, Q9BSM6	Gene names	GADD45GIP1, PLINP1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1 (CR6-interacting factor 1) (CRIF1) (CKII beta-associating protein) (Papillomavirus L2-interacting nuclear protein 1) (PLINP-1).

MYH4_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.013668 (rank : 81)
Query Neighborhood Hits	114	Target Neighborhood Hits	1476	Shared Neighborhood Hits	47
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

RADI_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.007460 (rank : 94)
Query Neighborhood Hits	114	Target Neighborhood Hits	741	Shared Neighborhood Hits	30
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

ANR26_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.014230 (rank : 79)
Query Neighborhood Hits	114	Target Neighborhood Hits	1554	Shared Neighborhood Hits	50
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CAF1A_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.022538 (rank : 53)
Query Neighborhood Hits	114	Target Neighborhood Hits	750	Shared Neighborhood Hits	33
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CAYP2_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.005672 (rank : 106)
Query Neighborhood Hits	114	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXY5, Q6PH84, Q8N242, Q8NAY5	Gene names	CAPS2
Domain Architecture
Description	Calcyphosin-2 (Calcyphosine-2).

DDX46_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.024683 (rank : 49)
Query Neighborhood Hits	114	Target Neighborhood Hits	357	Shared Neighborhood Hits	29
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	8.99809 (rank : 100)	NC score	0.025093 (rank : 47)
Query Neighborhood Hits	114	Target Neighborhood Hits	358	Shared Neighborhood Hits	30
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

E41L1_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.002687 (rank : 112)
Query Neighborhood Hits	114	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

FBN2_HUMAN
θ value	8.99809 (rank : 102)	NC score	-0.001536 (rank : 113)
Query Neighborhood Hits	114	Target Neighborhood Hits	560	Shared Neighborhood Hits	3
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FSBP_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.007075 (rank : 98)
Query Neighborhood Hits	114	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BKE5, Q8BJX8	Gene names	Fsbp
Domain Architecture	No domain graphic available
Description	Fibrinogen silencer-binding protein.

G45IP_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.012224 (rank : 86)
Query Neighborhood Hits	114	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CR59, Q8BT05	Gene names	Gadd45gip1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1.

K0776_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.006043 (rank : 102)
Query Neighborhood Hits	114	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	O94874, Q8N765, Q9NTQ0	Gene names	KIAA0776
Domain Architecture	No domain graphic available
Description	Protein KIAA0776.

KI21A_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.008461 (rank : 92)
Query Neighborhood Hits	114	Target Neighborhood Hits	1317	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

KIF3C_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.006762 (rank : 99)
Query Neighborhood Hits	114	Target Neighborhood Hits	478	Shared Neighborhood Hits	24
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.

MDN1_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.015790 (rank : 73)
Query Neighborhood Hits	114	Target Neighborhood Hits	662	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

NUCKS_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.007454 (rank : 95)
Query Neighborhood Hits	114	Target Neighborhood Hits	143	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

PEO1_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.026052 (rank : 44)
Query Neighborhood Hits	114	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q96RR1, Q6MZX2, Q96RR0	Gene names	PEO1, C10orf2
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein).

PININ_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.015518 (rank : 75)
Query Neighborhood Hits	114	Target Neighborhood Hits	777	Shared Neighborhood Hits	37
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

SFR12_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.011925 (rank : 89)
Query Neighborhood Hits	114	Target Neighborhood Hits	553	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

TFP11_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.007367 (rank : 96)
Query Neighborhood Hits	114	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERA6, Q8VD06	Gene names	Tfip11, Tip39
Domain Architecture
Description	Tuftelin-interacting protein 11 (Tuftelin-interacting protein 39).

TRAP1_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.008054 (rank : 93)
Query Neighborhood Hits	114	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQN1, Q542I4	Gene names	Trap1
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

Hits sorted by NC score

DHX36_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	114
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX36_HUMAN
NC score	0.994097 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	114	Target Neighborhood Hits	63	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX9_HUMAN
NC score	0.965279 (rank : 3)	θ value	5.9766e-145 (rank : 7)
Query Neighborhood Hits	114	Target Neighborhood Hits	62	Shared Neighborhood Hits	29
SwissProt Accessions	Q08211, Q5VY62, Q6PD69, Q99556	Gene names	DHX9, DDX9, NDH2
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9).

DHX9_MOUSE
NC score	0.962982 (rank : 4)	θ value	3.62588e-142 (rank : 8)
Query Neighborhood Hits	114	Target Neighborhood Hits	72	Shared Neighborhood Hits	27
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

DHX57_MOUSE
NC score	0.962172 (rank : 5)	θ value	1.15563e-172 (rank : 4)
Query Neighborhood Hits	114	Target Neighborhood Hits	125	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX29_MOUSE
NC score	0.962081 (rank : 6)	θ value	8.02161e-166 (rank : 6)
Query Neighborhood Hits	114	Target Neighborhood Hits	103	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PGC1, Q8BQJ4, Q8BT01, Q8C9B7, Q8C9H9	Gene names	Dhx29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29).

DHX57_HUMAN
NC score	0.960686 (rank : 7)	θ value	6.54689e-176 (rank : 3)
Query Neighborhood Hits	114	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX29_HUMAN
NC score	0.959894 (rank : 8)	θ value	1.6163e-166 (rank : 5)
Query Neighborhood Hits	114	Target Neighborhood Hits	144	Shared Neighborhood Hits	38
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

DHX30_HUMAN
NC score	0.957159 (rank : 9)	θ value	1.09172e-138 (rank : 9)
Query Neighborhood Hits	114	Target Neighborhood Hits	43	Shared Neighborhood Hits	25
SwissProt Accessions	Q7L2E3, O94965, Q7Z753, Q96CH4	Gene names	DHX30, KIAA0890
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX30_MOUSE
NC score	0.956653 (rank : 10)	θ value	2.97304e-136 (rank : 10)
Query Neighborhood Hits	114	Target Neighborhood Hits	45	Shared Neighborhood Hits	26
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX34_MOUSE
NC score	0.927727 (rank : 11)	θ value	2.54619e-95 (rank : 11)
Query Neighborhood Hits	114	Target Neighborhood Hits	235	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DBV3	Gene names	Dhx34, Ddx34, Kiaa0134
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX34_HUMAN
NC score	0.926410 (rank : 12)	θ value	1.73182e-43 (rank : 22)
Query Neighborhood Hits	114	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	Q14147	Gene names	DHX34, DDX34, KIAA0134
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX15_HUMAN
NC score	0.921505 (rank : 13)	θ value	5.32145e-85 (rank : 13)
Query Neighborhood Hits	114	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	O43143, Q9NQT7	Gene names	DHX15, DBP1, DDX15
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15) (ATP-dependent RNA helicase #46).

DHX15_MOUSE
NC score	0.921333 (rank : 14)	θ value	5.32145e-85 (rank : 14)
Query Neighborhood Hits	114	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	O35286, Q99L91	Gene names	Dhx15, Ddx15, Deah9
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15).

DHX35_HUMAN
NC score	0.920299 (rank : 15)	θ value	6.30065e-78 (rank : 15)
Query Neighborhood Hits	114	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H5Z1, Q5THR0, Q9H4H7, Q9H6T6	Gene names	DHX35, C20orf15, DDX35
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX35 (EC 3.6.1.-) (DEAH box protein 35).

DHX40_HUMAN
NC score	0.911173 (rank : 16)	θ value	1.45253e-74 (rank : 17)
Query Neighborhood Hits	114	Target Neighborhood Hits	34	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IX18, Q5JPH4, Q8TC86, Q8WY53, Q9BXM1, Q9H6M9	Gene names	DHX40, DDX40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40) (ARG147) (Protein PAD).

DHX40_MOUSE
NC score	0.910523 (rank : 17)	θ value	6.52014e-75 (rank : 16)
Query Neighborhood Hits	114	Target Neighborhood Hits	40	Shared Neighborhood Hits	29
SwissProt Accessions	Q6PE54, Q8BPH2, Q8CD88, Q9CWN3	Gene names	Dhx40
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX40 (EC 3.6.1.-) (DEAH box protein 40).

DHX8_HUMAN
NC score	0.908000 (rank : 18)	θ value	7.93343e-89 (rank : 12)
Query Neighborhood Hits	114	Target Neighborhood Hits	86	Shared Neighborhood Hits	29
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

DHX37_HUMAN
NC score	0.906958 (rank : 19)	θ value	7.47731e-63 (rank : 18)
Query Neighborhood Hits	114	Target Neighborhood Hits	133	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

PRP16_HUMAN
NC score	0.903714 (rank : 20)	θ value	2.65945e-60 (rank : 19)
Query Neighborhood Hits	114	Target Neighborhood Hits	135	Shared Neighborhood Hits	30
SwissProt Accessions	Q92620, O75212, Q96HN7	Gene names	DHX38, DDX38, KIAA0224, PRP16
Domain Architecture
Description	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.1.-) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38).

DHX33_MOUSE
NC score	0.902339 (rank : 21)	θ value	2.76489e-41 (rank : 23)
Query Neighborhood Hits	114	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	Q80VY9, Q8BS50	Gene names	Dhx33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

DHX33_HUMAN
NC score	0.896492 (rank : 22)	θ value	4.71619e-41 (rank : 24)
Query Neighborhood Hits	114	Target Neighborhood Hits	40	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H6R0, Q4G149, Q5CZ73, Q9H5M9	Gene names	DHX33
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX33 (EC 3.6.1.-) (DEAH box protein 33).

DHX16_HUMAN
NC score	0.870657 (rank : 23)	θ value	7.25919e-50 (rank : 20)
Query Neighborhood Hits	114	Target Neighborhood Hits	356	Shared Neighborhood Hits	50
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

YTDC2_HUMAN
NC score	0.853913 (rank : 24)	θ value	2.3352e-48 (rank : 21)
Query Neighborhood Hits	114	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H6S0	Gene names	YTHDC2
Domain Architecture	No domain graphic available
Description	YTH domain-containing protein 2.

SMBP2_HUMAN
NC score	0.058528 (rank : 25)	θ value	0.163984 (rank : 37)
Query Neighborhood Hits	114	Target Neighborhood Hits	107	Shared Neighborhood Hits	14
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

SMBP2_MOUSE
NC score	0.054623 (rank : 26)	θ value	0.365318 (rank : 44)
Query Neighborhood Hits	114	Target Neighborhood Hits	104	Shared Neighborhood Hits	11
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

SK2L2_MOUSE
NC score	0.051944 (rank : 27)	θ value	0.0252991 (rank : 26)
Query Neighborhood Hits	114	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CZU3	Gene names	Skiv2l2
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

SK2L2_HUMAN
NC score	0.049904 (rank : 28)	θ value	0.0736092 (rank : 33)
Query Neighborhood Hits	114	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	P42285, Q8TAG2	Gene names	SKIV2L2, KIAA0052
Domain Architecture	No domain graphic available
Description	Superkiller viralicidic activity 2-like 2 (EC 3.6.1.-) (ATP-dependent helicase SKIV2L2).

DDX50_HUMAN
NC score	0.046750 (rank : 29)	θ value	0.163984 (rank : 36)
Query Neighborhood Hits	114	Target Neighborhood Hits	132	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_MOUSE
NC score	0.043357 (rank : 30)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	114	Target Neighborhood Hits	137	Shared Neighborhood Hits	25
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

STIM1_MOUSE
NC score	0.042766 (rank : 31)	θ value	0.0563607 (rank : 31)
Query Neighborhood Hits	114	Target Neighborhood Hits	660	Shared Neighborhood Hits	43
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM1_HUMAN
NC score	0.042223 (rank : 32)	θ value	0.0330416 (rank : 27)
Query Neighborhood Hits	114	Target Neighborhood Hits	665	Shared Neighborhood Hits	43
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

TTF1_HUMAN
NC score	0.041637 (rank : 33)	θ value	0.0193708 (rank : 25)
Query Neighborhood Hits	114	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	Q15361, Q4VXF3, Q58EY2, Q6P5T5	Gene names	TTF1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (RNA polymerase I termination factor).

DDX49_HUMAN
NC score	0.041497 (rank : 34)	θ value	0.0431538 (rank : 30)
Query Neighborhood Hits	114	Target Neighborhood Hits	223	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

RENT2_HUMAN
NC score	0.037011 (rank : 35)	θ value	0.0736092 (rank : 32)
Query Neighborhood Hits	114	Target Neighborhood Hits	618	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

DDX49_MOUSE
NC score	0.036942 (rank : 36)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	114	Target Neighborhood Hits	119	Shared Neighborhood Hits	18
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

ZC313_HUMAN
NC score	0.033472 (rank : 37)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	114	Target Neighborhood Hits	772	Shared Neighborhood Hits	38
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

PEO1_MOUSE
NC score	0.031655 (rank : 38)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	114	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CIW5, Q8K1Z1	Gene names	Peo1
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein homolog).

DDX47_MOUSE
NC score	0.031185 (rank : 39)	θ value	0.0431538 (rank : 29)
Query Neighborhood Hits	114	Target Neighborhood Hits	97	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX21_MOUSE
NC score	0.030842 (rank : 40)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	114	Target Neighborhood Hits	350	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX47_HUMAN
NC score	0.030535 (rank : 41)	θ value	0.0431538 (rank : 28)
Query Neighborhood Hits	114	Target Neighborhood Hits	97	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

MAP1A_HUMAN
NC score	0.029738 (rank : 42)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	114	Target Neighborhood Hits	1626	Shared Neighborhood Hits	49
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

DDX10_MOUSE
NC score	0.027957 (rank : 43)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	114	Target Neighborhood Hits	233	Shared Neighborhood Hits	23
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

PEO1_HUMAN
NC score	0.026052 (rank : 44)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	114	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q96RR1, Q6MZX2, Q96RR0	Gene names	PEO1, C10orf2
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein).

CAF1A_MOUSE
NC score	0.025777 (rank : 45)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	114	Target Neighborhood Hits	736	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

DDX31_HUMAN
NC score	0.025776 (rank : 46)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	114	Target Neighborhood Hits	132	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX46_MOUSE
NC score	0.025093 (rank : 47)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	114	Target Neighborhood Hits	358	Shared Neighborhood Hits	30
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

TRHY_HUMAN
NC score	0.024854 (rank : 48)	θ value	0.125558 (rank : 35)
Query Neighborhood Hits	114	Target Neighborhood Hits	1385	Shared Neighborhood Hits	47
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

DDX46_HUMAN
NC score	0.024683 (rank : 49)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	114	Target Neighborhood Hits	357	Shared Neighborhood Hits	29
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

MD1L1_HUMAN
NC score	0.022742 (rank : 50)	θ value	0.47712 (rank : 47)
Query Neighborhood Hits	114	Target Neighborhood Hits	893	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

T2FA_HUMAN
NC score	0.022640 (rank : 51)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	114	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

MACOI_HUMAN
NC score	0.022604 (rank : 52)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	114	Target Neighborhood Hits	650	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

CAF1A_HUMAN
NC score	0.022538 (rank : 53)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	114	Target Neighborhood Hits	750	Shared Neighborhood Hits	33
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

MACOI_MOUSE
NC score	0.022297 (rank : 54)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	114	Target Neighborhood Hits	620	Shared Neighborhood Hits	36
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

TPR_HUMAN
NC score	0.022042 (rank : 55)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	114	Target Neighborhood Hits	1921	Shared Neighborhood Hits	55
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

FOLC_MOUSE
NC score	0.021883 (rank : 56)	θ value	0.47712 (rank : 45)
Query Neighborhood Hits	114	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P48760	Gene names	Fpgs
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).

GOGA4_MOUSE
NC score	0.021381 (rank : 57)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	114	Target Neighborhood Hits	1939	Shared Neighborhood Hits	58
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

AKAP9_HUMAN
NC score	0.020683 (rank : 58)	θ value	0.0961366 (rank : 34)
Query Neighborhood Hits	114	Target Neighborhood Hits	1710	Shared Neighborhood Hits	46
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

GOGB1_HUMAN
NC score	0.020621 (rank : 59)	θ value	0.47712 (rank : 46)
Query Neighborhood Hits	114	Target Neighborhood Hits	2297	Shared Neighborhood Hits	57
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

INVO_HUMAN
NC score	0.020061 (rank : 60)	θ value	0.62314 (rank : 51)
Query Neighborhood Hits	114	Target Neighborhood Hits	636	Shared Neighborhood Hits	28
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

CENPF_HUMAN
NC score	0.018909 (rank : 61)	θ value	0.279714 (rank : 40)
Query Neighborhood Hits	114	Target Neighborhood Hits	1932	Shared Neighborhood Hits	50
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

ASPM_HUMAN
NC score	0.018360 (rank : 62)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	114	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZT6, Q86UX4, Q8IUL2, Q8IZJ7, Q8IZJ8, Q8IZJ9, Q8N4D1, Q9NVS1, Q9NVT6	Gene names	ASPM, MCPH5
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog).

REXO4_MOUSE
NC score	0.017803 (rank : 63)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	114	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PAQ4, Q3UU17, Q8C524	Gene names	Rexo4, Gm111, Pmc2, Xpmc2h
Domain Architecture	No domain graphic available
Description	RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein homolog).

MY18B_HUMAN
NC score	0.016689 (rank : 64)	θ value	1.06291 (rank : 60)
Query Neighborhood Hits	114	Target Neighborhood Hits	1299	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

PEX26_HUMAN
NC score	0.016653 (rank : 65)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	114	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z412, Q7Z413, Q7Z414, Q7Z415, Q7Z416, Q96B12, Q9NWQ0, Q9NXU0	Gene names	PEX26
Domain Architecture
Description	Peroxisome assembly protein 26 (Peroxin-26).

CENPE_HUMAN
NC score	0.016356 (rank : 66)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	114	Target Neighborhood Hits	2060	Shared Neighborhood Hits	55
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

MYO6_HUMAN
NC score	0.016311 (rank : 67)	θ value	0.21417 (rank : 38)
Query Neighborhood Hits	114	Target Neighborhood Hits	727	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

CK5P2_HUMAN
NC score	0.016239 (rank : 68)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	114	Target Neighborhood Hits	1433	Shared Neighborhood Hits	50
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

SWP70_HUMAN
NC score	0.016186 (rank : 69)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	114	Target Neighborhood Hits	973	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

PLEC1_HUMAN
NC score	0.016115 (rank : 70)	θ value	0.21417 (rank : 39)
Query Neighborhood Hits	114	Target Neighborhood Hits	1326	Shared Neighborhood Hits	42
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

MYH8_MOUSE
NC score	0.015830 (rank : 71)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	114	Target Neighborhood Hits	1600	Shared Neighborhood Hits	53
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH8_HUMAN
NC score	0.015819 (rank : 72)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	114	Target Neighborhood Hits	1610	Shared Neighborhood Hits	53
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MDN1_HUMAN
NC score	0.015790 (rank : 73)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	114	Target Neighborhood Hits	662	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

GOGA6_HUMAN
NC score	0.015669 (rank : 74)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	114	Target Neighborhood Hits	1007	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

PININ_MOUSE
NC score	0.015518 (rank : 75)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	114	Target Neighborhood Hits	777	Shared Neighborhood Hits	37
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

MYH2_HUMAN
NC score	0.014773 (rank : 76)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	114	Target Neighborhood Hits	1491	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

G45IP_HUMAN
NC score	0.014712 (rank : 77)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	114	Target Neighborhood Hits	118	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TAE8, Q8IVM3, Q8TE51, Q969P9, Q9BSM6	Gene names	GADD45GIP1, PLINP1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1 (CR6-interacting factor 1) (CRIF1) (CKII beta-associating protein) (Papillomavirus L2-interacting nuclear protein 1) (PLINP-1).

ITSN1_HUMAN
NC score	0.014596 (rank : 78)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	114	Target Neighborhood Hits	1757	Shared Neighborhood Hits	52
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ANR26_MOUSE
NC score	0.014230 (rank : 79)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	114	Target Neighborhood Hits	1554	Shared Neighborhood Hits	50
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

DYXC1_HUMAN
NC score	0.014161 (rank : 80)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	114	Target Neighborhood Hits	261	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

MYH4_MOUSE
NC score	0.013668 (rank : 81)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	114	Target Neighborhood Hits	1476	Shared Neighborhood Hits	47
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

BAZ2B_HUMAN
NC score	0.013111 (rank : 82)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	114	Target Neighborhood Hits	803	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

TRAP1_HUMAN
NC score	0.013019 (rank : 83)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	114	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q12931, O43642, O75235, Q9UHL5	Gene names	TRAP1, HSP75
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

SNX23_HUMAN
NC score	0.012963 (rank : 84)	θ value	0.279714 (rank : 42)
Query Neighborhood Hits	114	Target Neighborhood Hits	944	Shared Neighborhood Hits	37
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

BRCA1_MOUSE
NC score	0.012456 (rank : 85)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	114	Target Neighborhood Hits	436	Shared Neighborhood Hits	9
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

G45IP_MOUSE
NC score	0.012224 (rank : 86)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	114	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CR59, Q8BT05	Gene names	Gadd45gip1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1.

DEN2A_MOUSE
NC score	0.012028 (rank : 87)	θ value	0.813845 (rank : 53)
Query Neighborhood Hits	114	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

ITSN2_MOUSE
NC score	0.011995 (rank : 88)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	114	Target Neighborhood Hits	1371	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

SFR12_HUMAN
NC score	0.011925 (rank : 89)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	114	Target Neighborhood Hits	553	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

ITSN2_HUMAN
NC score	0.010413 (rank : 90)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	114	Target Neighborhood Hits	1173	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

MAP9_HUMAN
NC score	0.010375 (rank : 91)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	114	Target Neighborhood Hits	518	Shared Neighborhood Hits	21
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

KI21A_MOUSE
NC score	0.008461 (rank : 92)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	114	Target Neighborhood Hits	1317	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

TRAP1_MOUSE
NC score	0.008054 (rank : 93)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	114	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQN1, Q542I4	Gene names	Trap1
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

RADI_HUMAN
NC score	0.007460 (rank : 94)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	114	Target Neighborhood Hits	741	Shared Neighborhood Hits	30
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

NUCKS_HUMAN
NC score	0.007454 (rank : 95)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	114	Target Neighborhood Hits	143	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

TFP11_MOUSE
NC score	0.007367 (rank : 96)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	114	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERA6, Q8VD06	Gene names	Tfip11, Tip39
Domain Architecture
Description	Tuftelin-interacting protein 11 (Tuftelin-interacting protein 39).

CTRO_MOUSE
NC score	0.007328 (rank : 97)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	114	Target Neighborhood Hits	2344	Shared Neighborhood Hits	55
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

FSBP_MOUSE
NC score	0.007075 (rank : 98)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	114	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BKE5, Q8BJX8	Gene names	Fsbp
Domain Architecture	No domain graphic available
Description	Fibrinogen silencer-binding protein.

KIF3C_HUMAN
NC score	0.006762 (rank : 99)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	114	Target Neighborhood Hits	478	Shared Neighborhood Hits	24
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.

SMCA2_HUMAN
NC score	0.006592 (rank : 100)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	114	Target Neighborhood Hits	503	Shared Neighborhood Hits	18
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
NC score	0.006206 (rank : 101)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	114	Target Neighborhood Hits	597	Shared Neighborhood Hits	19
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

K0776_HUMAN
NC score	0.006043 (rank : 102)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	114	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	O94874, Q8N765, Q9NTQ0	Gene names	KIAA0776
Domain Architecture	No domain graphic available
Description	Protein KIAA0776.

CAC1E_HUMAN
NC score	0.005912 (rank : 103)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	114	Target Neighborhood Hits	148	Shared Neighborhood Hits	6
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
NC score	0.005854 (rank : 104)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	114	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

SEM3D_HUMAN
NC score	0.005820 (rank : 105)	θ value	1.38821 (rank : 64)
Query Neighborhood Hits	114	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	O95025, Q6UW77, Q8NCQ1	Gene names	SEMA3D
Domain Architecture
Description	Semaphorin-3D precursor.

CAYP2_HUMAN
NC score	0.005672 (rank : 106)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	114	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXY5, Q6PH84, Q8N242, Q8NAY5	Gene names	CAPS2
Domain Architecture
Description	Calcyphosin-2 (Calcyphosine-2).

LAMC1_MOUSE
NC score	0.005103 (rank : 107)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	114	Target Neighborhood Hits	856	Shared Neighborhood Hits	27
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SEM3D_MOUSE
NC score	0.004861 (rank : 108)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	114	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BH34	Gene names	Sema3d
Domain Architecture	No domain graphic available
Description	Semaphorin-3D precursor.

CHD8_HUMAN
NC score	0.003925 (rank : 109)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	114	Target Neighborhood Hits	235	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

FGD3_HUMAN
NC score	0.003383 (rank : 110)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	114	Target Neighborhood Hits	249	Shared Neighborhood Hits	6
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

SCN2A_HUMAN
NC score	0.003337 (rank : 111)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	114	Target Neighborhood Hits	157	Shared Neighborhood Hits	7
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

E41L1_HUMAN
NC score	0.002687 (rank : 112)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	114	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

FBN2_HUMAN
NC score	-0.001536 (rank : 113)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	114	Target Neighborhood Hits	560	Shared Neighborhood Hits	3
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

ZBT11_HUMAN
NC score	-0.002936 (rank : 114)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	114	Target Neighborhood Hits	873	Shared Neighborhood Hits	5
SwissProt Accessions	O95625	Gene names	ZBTB11
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 11.