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Network neighborhood for query Sequence : CAYP2_HUMAN

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CAYP2_HUMAN
SwissProt Accessions	Q9BXY5, Q6PH84, Q8N242, Q8NAY5	Gene names	CAPS2
Domain Architecture
Description	Calcyphosin-2 (Calcyphosine-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAYP2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BXY5, Q6PH84, Q8N242, Q8NAY5	Gene names	CAPS2
Domain Architecture
Description	Calcyphosin-2 (Calcyphosine-2).

CAYP2_MOUSE
θ value	0 (rank : 2)	NC score	0.923933 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	35	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BUG5, Q8C1J6	Gene names	Caps2
Domain Architecture	No domain graphic available
Description	Calcyphosin-2 (Calcyphosine-2).

CAYP1_HUMAN
θ value	5.43371e-13 (rank : 3)	NC score	0.570543 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	94	Shared Neighborhood Hits	50
SwissProt Accessions	Q13938, Q3MJA7, Q8WUZ3	Gene names	CAPS
Domain Architecture
Description	Calcyphosin (Calcyphosine).

DJBP_HUMAN
θ value	1.09739e-05 (rank : 4)	NC score	0.290728 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	156	Shared Neighborhood Hits	50
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

DJBP_MOUSE
θ value	5.44631e-05 (rank : 5)	NC score	0.301030 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	152	Shared Neighborhood Hits	49
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

CETN2_HUMAN
θ value	0.00035302 (rank : 6)	NC score	0.251992 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	213	Shared Neighborhood Hits	63
SwissProt Accessions	P41208, Q53XW1	Gene names	CETN2, CALT, CEN2
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CETN1_HUMAN
θ value	0.00228821 (rank : 7)	NC score	0.251512 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	232	Shared Neighborhood Hits	63
SwissProt Accessions	Q12798	Gene names	CETN1, CEN1, CETN
Domain Architecture
Description	Centrin-1 (Caltractin isoform 2).

CETN2_MOUSE
θ value	0.00228821 (rank : 8)	NC score	0.246474 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	211	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R1K9, Q3UBB4, Q9CWM0	Gene names	Cetn2, Calt
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CALM4_MOUSE
θ value	0.00869519 (rank : 9)	NC score	0.233182 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	229	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

BPA1_MOUSE
θ value	0.0113563 (rank : 10)	NC score	0.092823 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	1477	Shared Neighborhood Hits	64
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CETN1_MOUSE
θ value	0.0148317 (rank : 11)	NC score	0.237392 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	231	Shared Neighborhood Hits	64
SwissProt Accessions	P41209, Q3V119, Q9D9G9, Q9DAL6	Gene names	Cetn1, Calt
Domain Architecture
Description	Centrin-1 (Caltractin).

CALN1_HUMAN
θ value	0.0252991 (rank : 12)	NC score	0.252926 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	161	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BXU9	Gene names	CALN1, CABP8
Domain Architecture
Description	Calneuron-1 (Calcium-binding protein CaBP8).

CALN1_MOUSE
θ value	0.0252991 (rank : 13)	NC score	0.252984 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	161	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JJG7	Gene names	Caln1
Domain Architecture
Description	Calneuron-1.

PDCD6_HUMAN
θ value	0.0252991 (rank : 14)	NC score	0.190299 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	141	Shared Neighborhood Hits	53
SwissProt Accessions	O75340	Gene names	PDCD6, ALG2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2).

PDCD6_MOUSE
θ value	0.0252991 (rank : 15)	NC score	0.191007 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	142	Shared Neighborhood Hits	53
SwissProt Accessions	P12815, Q545I0, Q61145	Gene names	Pdcd6, Alg2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2) (PMP41) (ALG-257).

RBCC1_MOUSE
θ value	0.0330416 (rank : 16)	NC score	0.044881 (rank : 157)
Query Neighborhood Hits	98	Target Neighborhood Hits	1048	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

ACTN2_HUMAN
θ value	0.0736092 (rank : 17)	NC score	0.111031 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	295	Shared Neighborhood Hits	48
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN2_MOUSE
θ value	0.0736092 (rank : 18)	NC score	0.110295 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	287	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

CALL3_HUMAN
θ value	0.0736092 (rank : 19)	NC score	0.226894 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	225	Shared Neighborhood Hits	68
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

CANB1_HUMAN
θ value	0.0961366 (rank : 20)	NC score	0.167481 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	183	Shared Neighborhood Hits	52
SwissProt Accessions	P63098, P06705, P15117, Q08044	Gene names	PPP3R1, CNA2, CNB
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB1_MOUSE
θ value	0.0961366 (rank : 21)	NC score	0.167472 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	183	Shared Neighborhood Hits	52
SwissProt Accessions	Q63810	Gene names	Ppp3r1, Cnb
Domain Architecture
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

EFHB_HUMAN
θ value	0.0961366 (rank : 22)	NC score	0.136315 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	125	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N7U6, Q6ZWK9, Q8IV58, Q96LQ6	Gene names	EFHB
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

TNNC1_MOUSE
θ value	0.0961366 (rank : 23)	NC score	0.219526 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	221	Shared Neighborhood Hits	67
SwissProt Accessions	P19123	Gene names	Tnnc1, Tncc
Domain Architecture
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

CABP1_HUMAN
θ value	0.125558 (rank : 24)	NC score	0.208195 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	197	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NZU7, O95663, Q9NZU8	Gene names	CABP1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1) (Calbrain).

CABP1_MOUSE
θ value	0.125558 (rank : 25)	NC score	0.208247 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	197	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JLK7, Q9JLK6	Gene names	Cabp1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1).

ANR12_HUMAN
θ value	0.163984 (rank : 26)	NC score	0.029612 (rank : 170)
Query Neighborhood Hits	98	Target Neighborhood Hits	1081	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

TNNT3_MOUSE
θ value	0.163984 (rank : 27)	NC score	0.050430 (rank : 155)
Query Neighborhood Hits	98	Target Neighborhood Hits	317	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

MACF1_HUMAN
θ value	0.21417 (rank : 28)	NC score	0.090649 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	1341	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF1_MOUSE
θ value	0.21417 (rank : 29)	NC score	0.091453 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	1313	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MACF4_HUMAN
θ value	0.21417 (rank : 30)	NC score	0.093884 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	1321	Shared Neighborhood Hits	66
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

TNNC1_HUMAN
θ value	0.21417 (rank : 31)	NC score	0.217143 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	219	Shared Neighborhood Hits	67
SwissProt Accessions	P63316, O14800, P02590, P04463	Gene names	TNNC1, TNNC
Domain Architecture	No domain graphic available
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

BPAEA_HUMAN
θ value	0.279714 (rank : 32)	NC score	0.091292 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	1369	Shared Neighborhood Hits	69
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MLRA_HUMAN
θ value	0.279714 (rank : 33)	NC score	0.163520 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	91	Shared Neighborhood Hits	44
SwissProt Accessions	Q01449	Gene names	MYL7, MYLC2A
Domain Architecture
Description	Myosin regulatory light chain 2, atrial isoform (Myosin light chain 2a) (MLC-2a) (MLC2a) (Myosin regulatory light chain 7).

MLRA_MOUSE
θ value	0.279714 (rank : 34)	NC score	0.163137 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	101	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QVP4, Q63977, Q9JIE8	Gene names	Myl7, Mylc2a
Domain Architecture
Description	Myosin regulatory light chain 2, atrial isoform (Myosin light chain 2a) (MLC-2a) (MLC2a) (Myosin regulatory light chain 7).

CABP7_HUMAN
θ value	0.365318 (rank : 35)	NC score	0.237943 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	205	Shared Neighborhood Hits	66
SwissProt Accessions	Q86V35	Gene names	CABP7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP7_MOUSE
θ value	0.365318 (rank : 36)	NC score	0.237943 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	205	Shared Neighborhood Hits	66
SwissProt Accessions	Q91ZM8	Gene names	Cabp7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

MYL6B_HUMAN
θ value	0.365318 (rank : 37)	NC score	0.173073 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	78	Shared Neighborhood Hits	41
SwissProt Accessions	P14649	Gene names	MYL6B, MLC1SA
Domain Architecture
Description	Myosin light polypeptide 6B (Smooth muscle and nonmuscle myosin light chain alkali 6B) (Myosin light chain 1 slow-twitch muscle A isoform) (MLC1sa).

YLPM1_HUMAN
θ value	0.365318 (rank : 38)	NC score	0.038610 (rank : 159)
Query Neighborhood Hits	98	Target Neighborhood Hits	670	Shared Neighborhood Hits	3
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

CALM_HUMAN
θ value	0.62314 (rank : 39)	NC score	0.219690 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	232	Shared Neighborhood Hits	68
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
θ value	0.62314 (rank : 40)	NC score	0.219690 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	232	Shared Neighborhood Hits	68
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

CABP2_MOUSE
θ value	0.813845 (rank : 41)	NC score	0.199833 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	204	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JLK4, Q9JLK5	Gene names	Cabp2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

LZTS1_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.030216 (rank : 167)
Query Neighborhood Hits	98	Target Neighborhood Hits	532	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

CCD11_HUMAN
θ value	1.06291 (rank : 43)	NC score	0.034513 (rank : 162)
Query Neighborhood Hits	98	Target Neighborhood Hits	822	Shared Neighborhood Hits	22
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

KI21B_MOUSE
θ value	1.06291 (rank : 44)	NC score	0.020274 (rank : 178)
Query Neighborhood Hits	98	Target Neighborhood Hits	997	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

MLRS_MOUSE
θ value	1.06291 (rank : 45)	NC score	0.146701 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	72	Shared Neighborhood Hits	41
SwissProt Accessions	P97457	Gene names	Mylpf
Domain Architecture
Description	Myosin regulatory light chain 2, skeletal muscle isoform (MLC2F).

ATRX_HUMAN
θ value	1.38821 (rank : 46)	NC score	0.020228 (rank : 179)
Query Neighborhood Hits	98	Target Neighborhood Hits	842	Shared Neighborhood Hits	11
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CABP2_HUMAN
θ value	1.38821 (rank : 47)	NC score	0.200114 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	205	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NPB3	Gene names	CABP2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CALL5_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.225638 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	231	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

RPGR1_HUMAN
θ value	1.38821 (rank : 49)	NC score	0.037311 (rank : 160)
Query Neighborhood Hits	98	Target Neighborhood Hits	578	Shared Neighborhood Hits	16
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

BAZ1B_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.020975 (rank : 176)
Query Neighborhood Hits	98	Target Neighborhood Hits	394	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

ITIH4_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.022343 (rank : 174)
Query Neighborhood Hits	98	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q14624, Q15135, Q9P190, Q9UQ54	Gene names	ITIH4, IHRP, ITIHL1, PK120
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H4 precursor (ITI heavy chain H4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (PK-120) (GP120) [Contains: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha- trypsin inhibitor heavy chain H4].

PLCB3_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.032604 (rank : 163)
Query Neighborhood Hits	98	Target Neighborhood Hits	445	Shared Neighborhood Hits	14
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

PLCB3_MOUSE
θ value	1.81305 (rank : 53)	NC score	0.030391 (rank : 166)
Query Neighborhood Hits	98	Target Neighborhood Hits	344	Shared Neighborhood Hits	10
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

GOGA4_MOUSE
θ value	2.36792 (rank : 54)	NC score	0.030742 (rank : 165)
Query Neighborhood Hits	98	Target Neighborhood Hits	1939	Shared Neighborhood Hits	28
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

TXLNB_MOUSE
θ value	2.36792 (rank : 55)	NC score	0.026879 (rank : 172)
Query Neighborhood Hits	98	Target Neighborhood Hits	640	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

CALL6_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.225286 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	157	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TD86, Q6Q2C4	Gene names	CALML6, CAGLP, CALGP
Domain Architecture	No domain graphic available
Description	Calmodulin-like protein 6 (Calglandulin-like protein).

CANB2_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.148179 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	163	Shared Neighborhood Hits	47
SwissProt Accessions	Q96LZ3, Q7Z4V8, Q8WYJ4	Gene names	PPP3R2, CBLP
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform) (Calcineurin B-like protein) (CBLP) (CNBII).

HELZ_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.022761 (rank : 173)
Query Neighborhood Hits	98	Target Neighborhood Hits	198	Shared Neighborhood Hits	4
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

KI21A_MOUSE
θ value	3.0926 (rank : 59)	NC score	0.017461 (rank : 180)
Query Neighborhood Hits	98	Target Neighborhood Hits	1317	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

KTN1_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.028416 (rank : 171)
Query Neighborhood Hits	98	Target Neighborhood Hits	1197	Shared Neighborhood Hits	19
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

ONCO_MOUSE
θ value	3.0926 (rank : 61)	NC score	0.147679 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	40
SwissProt Accessions	P51879, Q62004	Gene names	Ocm
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

PPE2_MOUSE
θ value	3.0926 (rank : 62)	NC score	0.058201 (rank : 141)
Query Neighborhood Hits	98	Target Neighborhood Hits	112	Shared Neighborhood Hits	34
SwissProt Accessions	O35385	Gene names	Ppef2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

DUOX1_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.070380 (rank : 124)
Query Neighborhood Hits	98	Target Neighborhood Hits	172	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NRD9, Q6ZMB3, Q6ZR09, Q9NZC1	Gene names	DUOX1, DUOX, LNOX1, THOX1
Domain Architecture	No domain graphic available
Description	Dual oxidase 1 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH thyroid oxidase 1) (Thyroid oxidase 1) (Large NOX 1) (Long NOX 1).

KCNH7_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.009864 (rank : 181)
Query Neighborhood Hits	98	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

MCFD2_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.057786 (rank : 142)
Query Neighborhood Hits	98	Target Neighborhood Hits	62	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NI22, Q8N3M5	Gene names	MCFD2, SDNSF
Domain Architecture
Description	Multiple coagulation factor deficiency protein 2 precursor (Neural stem cell-derived neuronal survival protein).

MYL6B_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.160749 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CI43	Gene names	Myl6b
Domain Architecture	No domain graphic available
Description	Myosin light polypeptide 6B (Smooth muscle and nonmuscle myosin light chain alkali 6B).

MYL6_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.157141 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	P60660, P16475, P24572, P24573, Q12790, Q6IAZ0, Q6IPY5	Gene names	MYL6
Domain Architecture
Description	Myosin light polypeptide 6 (Smooth muscle and nonmuscle myosin light chain alkali 6) (Myosin light chain alkali 3) (Myosin light chain 3) (MLC-3) (LC17).

MYL6_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.157141 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	Q60605	Gene names	Myl6, Myln
Domain Architecture
Description	Myosin light polypeptide 6 (Smooth muscle and nonmuscle myosin light chain alkali 6) (Myosin light chain alkali 3) (Myosin light chain 3) (MLC-3) (LC17).

SEL1L_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.029895 (rank : 168)
Query Neighborhood Hits	98	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBV2, Q6UWT6, Q9P1T9, Q9UHK7	Gene names	SEL1L, TSA305
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

SEL1L_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.029759 (rank : 169)
Query Neighborhood Hits	98	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2G6, Q9DBD8	Gene names	Sel1l, Sel1h
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

MLE1_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.143626 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	69	Shared Neighborhood Hits	37
SwissProt Accessions	P05977	Gene names	Myl1, Mylf
Domain Architecture
Description	Myosin light chain 1, skeletal muscle isoform (MLC1F) (A1 catalytic) (Alkali myosin light chain 1).

MLE3_MOUSE
θ value	5.27518 (rank : 72)	NC score	0.140665 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	66	Shared Neighborhood Hits	36
SwissProt Accessions	P05978	Gene names	Myl1, Mylf
Domain Architecture
Description	Myosin light chain 3, skeletal muscle isoform (A2 catalytic) (Alkali myosin light chain 3) (MLC3F).

RYR2_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.035376 (rank : 161)
Query Neighborhood Hits	98	Target Neighborhood Hits	175	Shared Neighborhood Hits	25
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

ZBTB1_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.001528 (rank : 184)
Query Neighborhood Hits	98	Target Neighborhood Hits	805	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2K1, Q86SW8	Gene names	ZBTB1, KIAA0997
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 1.

CETN3_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.220244 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	211	Shared Neighborhood Hits	63
SwissProt Accessions	O15182, Q9BS23	Gene names	CETN3, CEN3
Domain Architecture
Description	Centrin-3.

CETN3_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.220438 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	208	Shared Neighborhood Hits	63
SwissProt Accessions	O35648	Gene names	Cetn3, Cen3
Domain Architecture
Description	Centrin-3.

EFHB_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.090508 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	120	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CDU5	Gene names	Efhb
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

GUC1A_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.084911 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	152	Shared Neighborhood Hits	48
SwissProt Accessions	P43081	Gene names	Guca1a, Gcap, Gcap1, Guca1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

MCES_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.021690 (rank : 175)
Query Neighborhood Hits	98	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D0L8, Q3V3U9, Q6ZQC6, Q9D5F1	Gene names	Rnmt, Kiaa0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase).

NCALD_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.081656 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	153	Shared Neighborhood Hits	47
SwissProt Accessions	P61601, P29554, Q8IYC3, Q9H0W2	Gene names	NCALD
Domain Architecture
Description	Neurocalcin delta.

NCALD_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.081656 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	153	Shared Neighborhood Hits	47
SwissProt Accessions	Q91X97, Q3TJS9, Q8BZN9	Gene names	Ncald, D15Ertd412e
Domain Architecture
Description	Neurocalcin delta.

NOC3L_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.042524 (rank : 158)
Query Neighborhood Hits	98	Target Neighborhood Hits	135	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WTT2, Q9H5M6, Q9H9D8	Gene names	NOC3L, AD24, C10orf117, FAD24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

NOC3L_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.031463 (rank : 164)
Query Neighborhood Hits	98	Target Neighborhood Hits	177	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VI84, Q9JKM3	Gene names	Noc3l, Ad24, Fad24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

ONCO_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.143557 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	88	Shared Neighborhood Hits	40
SwissProt Accessions	P32930	Gene names	OCM, OCMN
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

ROCK2_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.007709 (rank : 182)
Query Neighborhood Hits	98	Target Neighborhood Hits	2072	Shared Neighborhood Hits	22
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

RYR1_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.020401 (rank : 177)
Query Neighborhood Hits	98	Target Neighborhood Hits	303	Shared Neighborhood Hits	5
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

VISL1_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.075605 (rank : 113)
Query Neighborhood Hits	98	Target Neighborhood Hits	124	Shared Neighborhood Hits	45
SwissProt Accessions	P62760, P28677, P29103, P42323, Q9UM20	Gene names	VSNL1, VISL1
Domain Architecture	No domain graphic available
Description	Visinin-like protein 1 (VILIP) (Hippocalcin-like protein 3) (HLP3).

VISL1_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.075605 (rank : 114)
Query Neighborhood Hits	98	Target Neighborhood Hits	124	Shared Neighborhood Hits	45
SwissProt Accessions	P62761, P28677, P29103, P42323, Q9UM20	Gene names	Vsnl1, Visl1
Domain Architecture	No domain graphic available
Description	Visinin-like protein 1 (VILIP) (Neural visinin-like protein 1) (NVL-1) (NVP-1).

ACTN3_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.094010 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	272	Shared Neighborhood Hits	44
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN3_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.095899 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	265	Shared Neighborhood Hits	45
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

CABP4_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.192226 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	212	Shared Neighborhood Hits	62
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

DHX36_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.005672 (rank : 183)
Query Neighborhood Hits	98	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

EFHC1_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.053701 (rank : 150)
Query Neighborhood Hits	98	Target Neighborhood Hits	65	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D9T8	Gene names	Efhc1
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing protein 1.

GUC1B_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.077882 (rank : 108)
Query Neighborhood Hits	98	Target Neighborhood Hits	124	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UMX6, Q9NU15	Gene names	GUCA1B, GCAP2
Domain Architecture
Description	Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B).

MCFD2_MOUSE
θ value	8.99809 (rank : 95)	NC score	0.049297 (rank : 156)
Query Neighborhood Hits	98	Target Neighborhood Hits	61	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K5B2, Q3U9G5	Gene names	Mcfd2, Sdnsf
Domain Architecture
Description	Multiple coagulation factor deficiency protein 2 homolog precursor (Neural stem cell-derived neuronal survival protein).

MLE1_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.140190 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	64	Shared Neighborhood Hits	37
SwissProt Accessions	P05976	Gene names	MYL1
Domain Architecture
Description	Myosin light chain 1, skeletal muscle isoform (MLC1F) (A1 catalytic) (Alkali myosin light chain 1).

MLE3_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.136870 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	60	Shared Neighborhood Hits	35
SwissProt Accessions	P06741	Gene names	MYL1
Domain Architecture
Description	Myosin light chain 3, skeletal muscle isoform (A2 catalytic) (Alkali myosin light chain 3) (MLC3F).

ZBTB1_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.001076 (rank : 185)
Query Neighborhood Hits	98	Target Neighborhood Hits	795	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VL9, Q8CDP7, Q99LD2	Gene names	Zbtb1
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 1.

ACTN1_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.087294 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	221	Shared Neighborhood Hits	42
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN1_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.086324 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	216	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN4_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.085414 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	279	Shared Neighborhood Hits	44
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN4_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.084379 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	276	Shared Neighborhood Hits	44
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

AIF1_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.067657 (rank : 128)
Query Neighborhood Hits	98	Target Neighborhood Hits	44	Shared Neighborhood Hits	25
SwissProt Accessions	P55008, Q9UKS9	Gene names	AIF1, G1, IBA1
Domain Architecture
Description	Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1).

AIF1_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.067191 (rank : 129)
Query Neighborhood Hits	98	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	O70200	Gene names	Aif1, Iba1
Domain Architecture	No domain graphic available
Description	Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1).

AYT1A_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.057397 (rank : 144)
Query Neighborhood Hits	98	Target Neighborhood Hits	126	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BYI6	Gene names	Aytl1a, Aytl1
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1-A (EC 2.3.1.-).

AYTL1_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.059861 (rank : 137)
Query Neighborhood Hits	98	Target Neighborhood Hits	140	Shared Neighborhood Hits	44
SwissProt Accessions	Q7L5N7, Q6MZJ6, Q9NX23	Gene names	AYTL1
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1 (EC 2.3.1.-).

CABP3_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.176273 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	162	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NZU6, Q9NYY0, Q9NZT9	Gene names	CABP3
Domain Architecture
Description	Calcium-binding protein 3 (CaBP3).

CABP4_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.187264 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	250	Shared Neighborhood Hits	61
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CABP5_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.194424 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	197	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CABP5_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.194296 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	207	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CALB1_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.078832 (rank : 105)
Query Neighborhood Hits	98	Target Neighborhood Hits	130	Shared Neighborhood Hits	45
SwissProt Accessions	P05937	Gene names	CALB1, CAB27
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K).

CALB1_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.079536 (rank : 103)
Query Neighborhood Hits	98	Target Neighborhood Hits	129	Shared Neighborhood Hits	46
SwissProt Accessions	P12658, Q545N6	Gene names	Calb1
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K) (Spot 35 protein) (PCD-29).

CALB2_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.090756 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	149	Shared Neighborhood Hits	50
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

CALB2_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.093676 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	141	Shared Neighborhood Hits	49
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

CANB2_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.149904 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	173	Shared Neighborhood Hits	51
SwissProt Accessions	Q63811	Gene names	Ppp3r2
Domain Architecture
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform).

CHP1_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.100817 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	114	Shared Neighborhood Hits	45
SwissProt Accessions	Q99653	Gene names	CHP
Domain Architecture
Description	Calcium-binding protein p22 (Calcium-binding protein CHP) (Calcineurin homologous protein) (Calcineurin B homolog).

CHP1_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.102099 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	117	Shared Neighborhood Hits	43
SwissProt Accessions	P61022, Q62877, Q6ZWQ8	Gene names	Chp, Sid470
Domain Architecture
Description	Calcium-binding protein p22 (Calcium-binding protein CHP) (Calcineurin homologous protein) (Sid 470).

CHP2_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.102662 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	122	Shared Neighborhood Hits	43
SwissProt Accessions	O43745	Gene names	CHP2, HCA520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520).

CHP2_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.104584 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	122	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D869	Gene names	Chp2, Hca520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520 homolog).

CPNS2_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.051751 (rank : 153)
Query Neighborhood Hits	98	Target Neighborhood Hits	66	Shared Neighborhood Hits	29
SwissProt Accessions	Q96L46, Q9BPV4	Gene names	CAPNS2
Domain Architecture
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

CSEN_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.055887 (rank : 145)
Query Neighborhood Hits	98	Target Neighborhood Hits	128	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y2W7, Q53TJ5, Q96T40, Q9UJ84, Q9UJ85	Gene names	KCNIP3, CSEN, DREAM, KCHIP3
Domain Architecture
Description	Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3) (A-type potassium channel modulatory protein 3).

CSEN_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.051869 (rank : 152)
Query Neighborhood Hits	98	Target Neighborhood Hits	117	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QXT8, Q924L0, Q99PH9, Q99PI0, Q99PI2, Q99PI3, Q9JHZ5	Gene names	Kcnip3, Csen, Dream, Kchip3
Domain Architecture
Description	Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (A-type potassium channel modulatory protein 3) (KChIP3).

DUOX2_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.055269 (rank : 149)
Query Neighborhood Hits	98	Target Neighborhood Hits	139	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NRD8, Q9NR02, Q9UHF9	Gene names	DUOX2, LNOX2, THOX2
Domain Architecture	No domain graphic available
Description	Dual oxidase 2 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Thyroid oxidase 2) (NADH/NADPH thyroid oxidase p138-tox) (p138 thyroid oxidase) (Large NOX 2) (Long NOX 2).

EFCB1_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.069412 (rank : 126)
Query Neighborhood Hits	98	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HAE3	Gene names	EFCAB1
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 1.

EFCB1_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.075784 (rank : 112)
Query Neighborhood Hits	98	Target Neighborhood Hits	126	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D3N2, Q8BSW3, Q8C982, Q8CAI0, Q9D527, Q9D5E7	Gene names	Efcab1
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 1.

EFCB2_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.143621 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	73	Shared Neighborhood Hits	36
SwissProt Accessions	Q5VUJ9, Q59G23, Q9BS36	Gene names	EFCAB2
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 2.

EFCB2_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.158829 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	64	Shared Neighborhood Hits	35
SwissProt Accessions	Q9CQ46, Q9CS07	Gene names	Efcab2
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 2.

EFCB3_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.073340 (rank : 120)
Query Neighborhood Hits	98	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N7B9	Gene names	EFCAB3
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 3.

EFCB3_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.076322 (rank : 111)
Query Neighborhood Hits	98	Target Neighborhood Hits	65	Shared Neighborhood Hits	30
SwissProt Accessions	Q80X60	Gene names	Efcab3
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 3.

EFHD1_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.099287 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	108	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BUP0, Q9BTF8, Q9H8I2, Q9HBQ0	Gene names	EFHD1, SWS2
Domain Architecture
Description	EF-hand domain-containing protein 1 (Swiprosin-2).

EFHD1_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.099435 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D4J1, Q543U4	Gene names	Efhd1, Sws2
Domain Architecture
Description	EF-hand domain-containing protein 1 (Swiprosin-2).

EFHD2_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.082533 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	86	Shared Neighborhood Hits	31
SwissProt Accessions	Q96C19	Gene names	EFHD2, SWS1
Domain Architecture
Description	EF-hand domain-containing protein 2 (Swiprosin-1).

EFHD2_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.083242 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D8Y0, Q9D0P4	Gene names	Efhd2, Sws1
Domain Architecture
Description	EF-hand domain-containing protein 2 (Swiprosin-1).

GPDM_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.080822 (rank : 99)
Query Neighborhood Hits	98	Target Neighborhood Hits	116	Shared Neighborhood Hits	34
SwissProt Accessions	P43304, Q59FR1, Q9HAP9	Gene names	GPD2
Domain Architecture
Description	Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M) (mtGPD).

GPDM_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.078691 (rank : 106)
Query Neighborhood Hits	98	Target Neighborhood Hits	101	Shared Neighborhood Hits	29
SwissProt Accessions	Q64521, Q61507	Gene names	Gpd2, Gdm1
Domain Architecture
Description	Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M).

GRAN_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.060948 (rank : 136)
Query Neighborhood Hits	98	Target Neighborhood Hits	57	Shared Neighborhood Hits	28
SwissProt Accessions	P28676	Gene names	GCA, GCL
Domain Architecture
Description	Grancalcin.

GUC1A_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.078888 (rank : 104)
Query Neighborhood Hits	98	Target Neighborhood Hits	147	Shared Neighborhood Hits	46
SwissProt Accessions	P43080, Q9NU14	Gene names	GUCA1A, GCAP, GCAP1, GUCA1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

GUC1B_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.064950 (rank : 130)
Query Neighborhood Hits	98	Target Neighborhood Hits	116	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VBV8	Gene names	Guca1b
Domain Architecture	No domain graphic available
Description	Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B).

GUC1C_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.081953 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	148	Shared Neighborhood Hits	41
SwissProt Accessions	O95843, O95844, Q9UNM0	Gene names	GUCA1C, GCAP3
Domain Architecture
Description	Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C).

HPCA_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.073409 (rank : 118)
Query Neighborhood Hits	98	Target Neighborhood Hits	156	Shared Neighborhood Hits	49
SwissProt Accessions	P84074, P32076, P41211, P70510	Gene names	HPCA, BDR2
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2).

HPCA_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.073409 (rank : 119)
Query Neighborhood Hits	98	Target Neighborhood Hits	156	Shared Neighborhood Hits	49
SwissProt Accessions	P84075, P32076, P41211, P70510	Gene names	Hpca
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin.

HPCL1_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.076545 (rank : 110)
Query Neighborhood Hits	98	Target Neighborhood Hits	150	Shared Neighborhood Hits	47
SwissProt Accessions	P37235, Q969S5	Gene names	HPCAL1, BDR1
Domain Architecture
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Calcium-binding protein BDR-1) (HLP2).

HPCL1_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.074045 (rank : 117)
Query Neighborhood Hits	98	Target Neighborhood Hits	149	Shared Neighborhood Hits	48
SwissProt Accessions	P62748, P35333	Gene names	Hpcal1
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Neural visinin-like protein 3) (NVL-3) (NVP-3).

HPCL4_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.071451 (rank : 122)
Query Neighborhood Hits	98	Target Neighborhood Hits	123	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UM19, Q5TG97, Q8N611	Gene names	HPCAL4
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 4 (HLP4).

HPCL4_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.071449 (rank : 123)
Query Neighborhood Hits	98	Target Neighborhood Hits	123	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BGZ1	Gene names	Hpcal4
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 4 (Neural visinin-like protein 2) (NVP-2).

IBA2_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.062905 (rank : 133)
Query Neighborhood Hits	98	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BQI0, Q6ZR40, Q8NAX7, Q8WU47, Q9H9G0	Gene names	IBA2, C9orf58
Domain Architecture	No domain graphic available
Description	Ionized calcium-binding adapter molecule 2.

IBA2_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.063884 (rank : 131)
Query Neighborhood Hits	98	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQX4, Q8C150	Gene names	Iba2
Domain Architecture	No domain graphic available
Description	Ionized calcium-binding adapter molecule 2.

KCIP4_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.055325 (rank : 147)
Query Neighborhood Hits	98	Target Neighborhood Hits	136	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PIL6, Q4W5G8, Q8NEU0, Q9BWT2, Q9H294, Q9H2A4	Gene names	KCNIP4, CALP, KCHIP4
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Potassium channel-interacting protein 4) (Calsenilin-like protein).

KCIP4_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.055311 (rank : 148)
Query Neighborhood Hits	98	Target Neighborhood Hits	136	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PHZ8, Q6DTJ3, Q8CAD0, Q8R4I2, Q9EQ01	Gene names	Kcnip4, Calp, Kchip4
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Potassium channel-interacting protein 4) (Calsenilin-like protein).

KIP1_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.074845 (rank : 115)
Query Neighborhood Hits	98	Target Neighborhood Hits	105	Shared Neighborhood Hits	38
SwissProt Accessions	Q99828, O00693, O00735, Q6IB49, Q96J54, Q99971	Gene names	CIB1, CIB, KIP, PRKDCIP
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB) (SNK- interacting protein 2-28) (SIP2-28).

KIP1_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.074379 (rank : 116)
Query Neighborhood Hits	98	Target Neighborhood Hits	109	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z0F4, Q3TN80	Gene names	Cib1, Cib, Kip, Prkdcip
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB).

KIP2_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.088650 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	107	Shared Neighborhood Hits	40
SwissProt Accessions	O75838	Gene names	CIB2, KIP2
Domain Architecture	No domain graphic available
Description	Calcium and integrin-binding protein 2 (Kinase-interacting protein 2) (KIP 2).

KIP2_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.087878 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	110	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z309	Gene names	Cib2, Kip2
Domain Architecture	No domain graphic available
Description	Calcium and integrin-binding protein 2 (Kinase-interacting protein 2) (KIP 2).

KIP3_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.077101 (rank : 109)
Query Neighborhood Hits	98	Target Neighborhood Hits	83	Shared Neighborhood Hits	31
SwissProt Accessions	Q96Q77	Gene names	CIB3, KIP3
Domain Architecture
Description	Calcium and integrin-binding protein 3 (Kinase-interacting protein 3) (KIP 3).

MLR5_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.153223 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	90	Shared Neighborhood Hits	46
SwissProt Accessions	Q02045	Gene names	MYL5
Domain Architecture
Description	Superfast myosin regulatory light chain 2 (MyLC-2) (MYLC2) (Myosin regulatory light chain 5).

MLRM_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.164472 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	111	Shared Neighborhood Hits	44
SwissProt Accessions	P19105	Gene names	MRLC2, MLCB, RLC
Domain Architecture
Description	Myosin regulatory light chain 2, nonsarcomeric (Myosin RLC).

MLRN_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.163918 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	107	Shared Neighborhood Hits	45
SwissProt Accessions	P24844, Q9H136	Gene names	MYL9, MLC2, MRLC1, MYRL2
Domain Architecture
Description	Myosin regulatory light chain 2, smooth muscle isoform (Myosin RLC) (Myosin regulatory light chain 9) (LC20).

MLRN_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.162763 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	106	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CQ19, Q80X77	Gene names	Myl9, Myrl2
Domain Architecture
Description	Myosin regulatory light chain 2, smooth muscle isoform (Myosin RLC) (Myosin regulatory light chain 9).

MLRV_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.144719 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	89	Shared Neighborhood Hits	46
SwissProt Accessions	P10916, Q16123	Gene names	MYL2
Domain Architecture
Description	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v).

MLRV_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.142724 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	89	Shared Neighborhood Hits	44
SwissProt Accessions	P51667	Gene names	Myl2, Mylpc
Domain Architecture
Description	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v).

MYL3_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.129338 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	66	Shared Neighborhood Hits	37
SwissProt Accessions	P08590, Q9NRS8	Gene names	MYL3
Domain Architecture
Description	Myosin light polypeptide 3 (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain) (Cardiac myosin light chain-1) (CMLC1).

MYL3_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.132781 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	70	Shared Neighborhood Hits	37
SwissProt Accessions	P09542, Q3UIF4, Q9CQZ2	Gene names	Myl3, Mlc1v, Mylc
Domain Architecture
Description	Myosin light polypeptide 3 (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain).

MYL4_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.126045 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	66	Shared Neighborhood Hits	36
SwissProt Accessions	P12829, P11783	Gene names	MYL4, MLC1
Domain Architecture
Description	Myosin light polypeptide 4 (Myosin light chain 1, embryonic muscle/atrial isoform) (Myosin light chain alkali, GT-1 isoform).

MYL4_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.125854 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	63	Shared Neighborhood Hits	38
SwissProt Accessions	P09541	Gene names	Myl4, Mlc1a, Myla
Domain Architecture
Description	Myosin light polypeptide 4 (Myosin light chain 1, atrial/fetal isoform) (MLC1A) (MLC1EMB).

NCS1_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.058788 (rank : 139)
Query Neighborhood Hits	98	Target Neighborhood Hits	132	Shared Neighborhood Hits	39
SwissProt Accessions	P62166, P36610, Q9UK26	Gene names	FREQ, FLUP, NCS1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein).

NCS1_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.058788 (rank : 140)
Query Neighborhood Hits	98	Target Neighborhood Hits	132	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BNY6	Gene names	Freq, Ncs1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog).

PEF1_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.059109 (rank : 138)
Query Neighborhood Hits	98	Target Neighborhood Hits	135	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

PEF1_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.061272 (rank : 135)
Query Neighborhood Hits	98	Target Neighborhood Hits	112	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BFY6, Q8VCT5, Q9CYW8, Q9D934	Gene names	Pef1
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

PLSI_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.080608 (rank : 100)
Query Neighborhood Hits	98	Target Neighborhood Hits	209	Shared Neighborhood Hits	48
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

PLSL_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.078421 (rank : 107)
Query Neighborhood Hits	98	Target Neighborhood Hits	168	Shared Neighborhood Hits	43
SwissProt Accessions	P13796	Gene names	LCP1, PLS2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P).

PLSL_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.079646 (rank : 102)
Query Neighborhood Hits	98	Target Neighborhood Hits	170	Shared Neighborhood Hits	43
SwissProt Accessions	Q61233, Q3UE24, Q8R1X3, Q9CV77	Gene names	Lcp1, Pls2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (pp65).

PLST_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.069491 (rank : 125)
Query Neighborhood Hits	98	Target Neighborhood Hits	161	Shared Neighborhood Hits	41
SwissProt Accessions	P13797, Q86YI6	Gene names	PLS3
Domain Architecture
Description	Plastin-3 (T-plastin).

PLST_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.069012 (rank : 127)
Query Neighborhood Hits	98	Target Neighborhood Hits	156	Shared Neighborhood Hits	42
SwissProt Accessions	Q99K51	Gene names	Pls3
Domain Architecture	No domain graphic available
Description	Plastin-3 (T-plastin).

PRVA_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.117191 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	P20472, P78378, Q4VB78, Q5R3Q9	Gene names	PVALB
Domain Architecture	No domain graphic available
Description	Parvalbumin alpha.

PRVA_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.131508 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	P32848	Gene names	Pvalb, Pva
Domain Architecture
Description	Parvalbumin alpha.

RCN2_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.057520 (rank : 143)
Query Neighborhood Hits	98	Target Neighborhood Hits	95	Shared Neighborhood Hits	39
SwissProt Accessions	Q14257	Gene names	RCN2, ERC55
Domain Architecture
Description	Reticulocalbin-2 precursor (Calcium-binding protein ERC-55) (E6- binding protein) (E6BP).

RCN2_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.062966 (rank : 132)
Query Neighborhood Hits	98	Target Neighborhood Hits	108	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BP92, O70341	Gene names	Rcn2
Domain Architecture	No domain graphic available
Description	Reticulocalbin-2 precursor (Taipoxin-associated calcium-binding protein 49) (TCBP-49).

RECO_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.051464 (rank : 154)
Query Neighborhood Hits	98	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	P35243	Gene names	RCVRN, RCV1
Domain Architecture
Description	Recoverin (Cancer-associated retinopathy protein) (Protein CAR).

RECO_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.055635 (rank : 146)
Query Neighborhood Hits	98	Target Neighborhood Hits	108	Shared Neighborhood Hits	34
SwissProt Accessions	P34057	Gene names	Rcvrn, Rcv1
Domain Architecture
Description	Recoverin (Cancer-associated retinopathy protein) (Protein CAR) (23 kDa photoreceptor cell-specific protein).

SEGN_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.053495 (rank : 151)
Query Neighborhood Hits	98	Target Neighborhood Hits	96	Shared Neighborhood Hits	29
SwissProt Accessions	O76038, Q5VV44, Q96QV7, Q9UJF6	Gene names	SCGN, SECRET
Domain Architecture
Description	Secretagogin.

SORCN_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.071456 (rank : 121)
Query Neighborhood Hits	98	Target Neighborhood Hits	82	Shared Neighborhood Hits	37
SwissProt Accessions	P30626	Gene names	SRI
Domain Architecture
Description	Sorcin (22 kDa protein) (CP-22) (V19).

SORCN_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.062539 (rank : 134)
Query Neighborhood Hits	98	Target Neighborhood Hits	72	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P069, Q3UKC5, Q9CR38, Q9D7V8	Gene names	Sri
Domain Architecture	No domain graphic available
Description	Sorcin.

SPTA2_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.079956 (rank : 101)
Query Neighborhood Hits	98	Target Neighborhood Hits	888	Shared Neighborhood Hits	58
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

TNNC2_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.201281 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	234	Shared Neighborhood Hits	67
SwissProt Accessions	P02585	Gene names	TNNC2
Domain Architecture
Description	Troponin C, skeletal muscle.

TNNC2_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.199951 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	233	Shared Neighborhood Hits	67
SwissProt Accessions	P20801	Gene names	Tnnc2, Tncs
Domain Architecture
Description	Troponin C, skeletal muscle (STNC).

Hits sorted by NC score

CAYP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BXY5, Q6PH84, Q8N242, Q8NAY5	Gene names	CAPS2
Domain Architecture
Description	Calcyphosin-2 (Calcyphosine-2).

CAYP2_MOUSE
NC score	0.923933 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	35	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BUG5, Q8C1J6	Gene names	Caps2
Domain Architecture	No domain graphic available
Description	Calcyphosin-2 (Calcyphosine-2).

CAYP1_HUMAN
NC score	0.570543 (rank : 3)	θ value	5.43371e-13 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	94	Shared Neighborhood Hits	50
SwissProt Accessions	Q13938, Q3MJA7, Q8WUZ3	Gene names	CAPS
Domain Architecture
Description	Calcyphosin (Calcyphosine).

DJBP_MOUSE
NC score	0.301030 (rank : 4)	θ value	5.44631e-05 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	152	Shared Neighborhood Hits	49
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

DJBP_HUMAN
NC score	0.290728 (rank : 5)	θ value	1.09739e-05 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	156	Shared Neighborhood Hits	50
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

CALN1_MOUSE
NC score	0.252984 (rank : 6)	θ value	0.0252991 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	161	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JJG7	Gene names	Caln1
Domain Architecture
Description	Calneuron-1.

CALN1_HUMAN
NC score	0.252926 (rank : 7)	θ value	0.0252991 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	161	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BXU9	Gene names	CALN1, CABP8
Domain Architecture
Description	Calneuron-1 (Calcium-binding protein CaBP8).

CETN2_HUMAN
NC score	0.251992 (rank : 8)	θ value	0.00035302 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	213	Shared Neighborhood Hits	63
SwissProt Accessions	P41208, Q53XW1	Gene names	CETN2, CALT, CEN2
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CETN1_HUMAN
NC score	0.251512 (rank : 9)	θ value	0.00228821 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	232	Shared Neighborhood Hits	63
SwissProt Accessions	Q12798	Gene names	CETN1, CEN1, CETN
Domain Architecture
Description	Centrin-1 (Caltractin isoform 2).

CETN2_MOUSE
NC score	0.246474 (rank : 10)	θ value	0.00228821 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	211	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R1K9, Q3UBB4, Q9CWM0	Gene names	Cetn2, Calt
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CABP7_HUMAN
NC score	0.237943 (rank : 11)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	205	Shared Neighborhood Hits	66
SwissProt Accessions	Q86V35	Gene names	CABP7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP7_MOUSE
NC score	0.237943 (rank : 12)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	205	Shared Neighborhood Hits	66
SwissProt Accessions	Q91ZM8	Gene names	Cabp7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CETN1_MOUSE
NC score	0.237392 (rank : 13)	θ value	0.0148317 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	231	Shared Neighborhood Hits	64
SwissProt Accessions	P41209, Q3V119, Q9D9G9, Q9DAL6	Gene names	Cetn1, Calt
Domain Architecture
Description	Centrin-1 (Caltractin).

CALM4_MOUSE
NC score	0.233182 (rank : 14)	θ value	0.00869519 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	229	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

CALL3_HUMAN
NC score	0.226894 (rank : 15)	θ value	0.0736092 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	225	Shared Neighborhood Hits	68
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

CALL5_HUMAN
NC score	0.225638 (rank : 16)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	231	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

CALL6_HUMAN
NC score	0.225286 (rank : 17)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	157	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TD86, Q6Q2C4	Gene names	CALML6, CAGLP, CALGP
Domain Architecture	No domain graphic available
Description	Calmodulin-like protein 6 (Calglandulin-like protein).

CETN3_MOUSE
NC score	0.220438 (rank : 18)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	208	Shared Neighborhood Hits	63
SwissProt Accessions	O35648	Gene names	Cetn3, Cen3
Domain Architecture
Description	Centrin-3.

CETN3_HUMAN
NC score	0.220244 (rank : 19)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	211	Shared Neighborhood Hits	63
SwissProt Accessions	O15182, Q9BS23	Gene names	CETN3, CEN3
Domain Architecture
Description	Centrin-3.

CALM_HUMAN
NC score	0.219690 (rank : 20)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	232	Shared Neighborhood Hits	68
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
NC score	0.219690 (rank : 21)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	232	Shared Neighborhood Hits	68
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

TNNC1_MOUSE
NC score	0.219526 (rank : 22)	θ value	0.0961366 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	221	Shared Neighborhood Hits	67
SwissProt Accessions	P19123	Gene names	Tnnc1, Tncc
Domain Architecture
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

TNNC1_HUMAN
NC score	0.217143 (rank : 23)	θ value	0.21417 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	219	Shared Neighborhood Hits	67
SwissProt Accessions	P63316, O14800, P02590, P04463	Gene names	TNNC1, TNNC
Domain Architecture	No domain graphic available
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

CABP1_MOUSE
NC score	0.208247 (rank : 24)	θ value	0.125558 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	197	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JLK7, Q9JLK6	Gene names	Cabp1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1).

CABP1_HUMAN
NC score	0.208195 (rank : 25)	θ value	0.125558 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	197	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NZU7, O95663, Q9NZU8	Gene names	CABP1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1) (Calbrain).

TNNC2_HUMAN
NC score	0.201281 (rank : 26)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	98	Target Neighborhood Hits	234	Shared Neighborhood Hits	67
SwissProt Accessions	P02585	Gene names	TNNC2
Domain Architecture
Description	Troponin C, skeletal muscle.

CABP2_HUMAN
NC score	0.200114 (rank : 27)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	205	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NPB3	Gene names	CABP2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

TNNC2_MOUSE
NC score	0.199951 (rank : 28)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	98	Target Neighborhood Hits	233	Shared Neighborhood Hits	67
SwissProt Accessions	P20801	Gene names	Tnnc2, Tncs
Domain Architecture
Description	Troponin C, skeletal muscle (STNC).

CABP2_MOUSE
NC score	0.199833 (rank : 29)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	204	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JLK4, Q9JLK5	Gene names	Cabp2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CABP5_HUMAN
NC score	0.194424 (rank : 30)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	98	Target Neighborhood Hits	197	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CABP5_MOUSE
NC score	0.194296 (rank : 31)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	98	Target Neighborhood Hits	207	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CABP4_MOUSE
NC score	0.192226 (rank : 32)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	212	Shared Neighborhood Hits	62
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

PDCD6_MOUSE
NC score	0.191007 (rank : 33)	θ value	0.0252991 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	142	Shared Neighborhood Hits	53
SwissProt Accessions	P12815, Q545I0, Q61145	Gene names	Pdcd6, Alg2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2) (PMP41) (ALG-257).

PDCD6_HUMAN
NC score	0.190299 (rank : 34)	θ value	0.0252991 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	141	Shared Neighborhood Hits	53
SwissProt Accessions	O75340	Gene names	PDCD6, ALG2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2).

CABP4_HUMAN
NC score	0.187264 (rank : 35)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	98	Target Neighborhood Hits	250	Shared Neighborhood Hits	61
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CABP3_HUMAN
NC score	0.176273 (rank : 36)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	98	Target Neighborhood Hits	162	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NZU6, Q9NYY0, Q9NZT9	Gene names	CABP3
Domain Architecture
Description	Calcium-binding protein 3 (CaBP3).

MYL6B_HUMAN
NC score	0.173073 (rank : 37)	θ value	0.365318 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	78	Shared Neighborhood Hits	41
SwissProt Accessions	P14649	Gene names	MYL6B, MLC1SA
Domain Architecture
Description	Myosin light polypeptide 6B (Smooth muscle and nonmuscle myosin light chain alkali 6B) (Myosin light chain 1 slow-twitch muscle A isoform) (MLC1sa).

CANB1_HUMAN
NC score	0.167481 (rank : 38)	θ value	0.0961366 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	183	Shared Neighborhood Hits	52
SwissProt Accessions	P63098, P06705, P15117, Q08044	Gene names	PPP3R1, CNA2, CNB
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB1_MOUSE
NC score	0.167472 (rank : 39)	θ value	0.0961366 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	183	Shared Neighborhood Hits	52
SwissProt Accessions	Q63810	Gene names	Ppp3r1, Cnb
Domain Architecture
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

MLRM_HUMAN
NC score	0.164472 (rank : 40)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	98	Target Neighborhood Hits	111	Shared Neighborhood Hits	44
SwissProt Accessions	P19105	Gene names	MRLC2, MLCB, RLC
Domain Architecture
Description	Myosin regulatory light chain 2, nonsarcomeric (Myosin RLC).

MLRN_HUMAN
NC score	0.163918 (rank : 41)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	98	Target Neighborhood Hits	107	Shared Neighborhood Hits	45
SwissProt Accessions	P24844, Q9H136	Gene names	MYL9, MLC2, MRLC1, MYRL2
Domain Architecture
Description	Myosin regulatory light chain 2, smooth muscle isoform (Myosin RLC) (Myosin regulatory light chain 9) (LC20).

MLRA_HUMAN
NC score	0.163520 (rank : 42)	θ value	0.279714 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	91	Shared Neighborhood Hits	44
SwissProt Accessions	Q01449	Gene names	MYL7, MYLC2A
Domain Architecture
Description	Myosin regulatory light chain 2, atrial isoform (Myosin light chain 2a) (MLC-2a) (MLC2a) (Myosin regulatory light chain 7).

MLRA_MOUSE
NC score	0.163137 (rank : 43)	θ value	0.279714 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	101	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QVP4, Q63977, Q9JIE8	Gene names	Myl7, Mylc2a
Domain Architecture
Description	Myosin regulatory light chain 2, atrial isoform (Myosin light chain 2a) (MLC-2a) (MLC2a) (Myosin regulatory light chain 7).

MLRN_MOUSE
NC score	0.162763 (rank : 44)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	98	Target Neighborhood Hits	106	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CQ19, Q80X77	Gene names	Myl9, Myrl2
Domain Architecture
Description	Myosin regulatory light chain 2, smooth muscle isoform (Myosin RLC) (Myosin regulatory light chain 9).

MYL6B_MOUSE
NC score	0.160749 (rank : 45)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CI43	Gene names	Myl6b
Domain Architecture	No domain graphic available
Description	Myosin light polypeptide 6B (Smooth muscle and nonmuscle myosin light chain alkali 6B).

EFCB2_MOUSE
NC score	0.158829 (rank : 46)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	98	Target Neighborhood Hits	64	Shared Neighborhood Hits	35
SwissProt Accessions	Q9CQ46, Q9CS07	Gene names	Efcab2
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 2.

MYL6_HUMAN
NC score	0.157141 (rank : 47)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	P60660, P16475, P24572, P24573, Q12790, Q6IAZ0, Q6IPY5	Gene names	MYL6
Domain Architecture
Description	Myosin light polypeptide 6 (Smooth muscle and nonmuscle myosin light chain alkali 6) (Myosin light chain alkali 3) (Myosin light chain 3) (MLC-3) (LC17).

MYL6_MOUSE
NC score	0.157141 (rank : 48)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	Q60605	Gene names	Myl6, Myln
Domain Architecture
Description	Myosin light polypeptide 6 (Smooth muscle and nonmuscle myosin light chain alkali 6) (Myosin light chain alkali 3) (Myosin light chain 3) (MLC-3) (LC17).

MLR5_HUMAN
NC score	0.153223 (rank : 49)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	98	Target Neighborhood Hits	90	Shared Neighborhood Hits	46
SwissProt Accessions	Q02045	Gene names	MYL5
Domain Architecture
Description	Superfast myosin regulatory light chain 2 (MyLC-2) (MYLC2) (Myosin regulatory light chain 5).

CANB2_MOUSE
NC score	0.149904 (rank : 50)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	98	Target Neighborhood Hits	173	Shared Neighborhood Hits	51
SwissProt Accessions	Q63811	Gene names	Ppp3r2
Domain Architecture
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform).

CANB2_HUMAN
NC score	0.148179 (rank : 51)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	163	Shared Neighborhood Hits	47
SwissProt Accessions	Q96LZ3, Q7Z4V8, Q8WYJ4	Gene names	PPP3R2, CBLP
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform) (Calcineurin B-like protein) (CBLP) (CNBII).

ONCO_MOUSE
NC score	0.147679 (rank : 52)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	40
SwissProt Accessions	P51879, Q62004	Gene names	Ocm
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

MLRS_MOUSE
NC score	0.146701 (rank : 53)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	72	Shared Neighborhood Hits	41
SwissProt Accessions	P97457	Gene names	Mylpf
Domain Architecture
Description	Myosin regulatory light chain 2, skeletal muscle isoform (MLC2F).

MLRV_HUMAN
NC score	0.144719 (rank : 54)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	98	Target Neighborhood Hits	89	Shared Neighborhood Hits	46
SwissProt Accessions	P10916, Q16123	Gene names	MYL2
Domain Architecture
Description	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v).

MLE1_MOUSE
NC score	0.143626 (rank : 55)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	69	Shared Neighborhood Hits	37
SwissProt Accessions	P05977	Gene names	Myl1, Mylf
Domain Architecture
Description	Myosin light chain 1, skeletal muscle isoform (MLC1F) (A1 catalytic) (Alkali myosin light chain 1).

EFCB2_HUMAN
NC score	0.143621 (rank : 56)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	98	Target Neighborhood Hits	73	Shared Neighborhood Hits	36
SwissProt Accessions	Q5VUJ9, Q59G23, Q9BS36	Gene names	EFCAB2
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 2.

ONCO_HUMAN
NC score	0.143557 (rank : 57)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	88	Shared Neighborhood Hits	40
SwissProt Accessions	P32930	Gene names	OCM, OCMN
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

MLRV_MOUSE
NC score	0.142724 (rank : 58)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	98	Target Neighborhood Hits	89	Shared Neighborhood Hits	44
SwissProt Accessions	P51667	Gene names	Myl2, Mylpc
Domain Architecture
Description	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v).

MLE3_MOUSE
NC score	0.140665 (rank : 59)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	66	Shared Neighborhood Hits	36
SwissProt Accessions	P05978	Gene names	Myl1, Mylf
Domain Architecture
Description	Myosin light chain 3, skeletal muscle isoform (A2 catalytic) (Alkali myosin light chain 3) (MLC3F).

MLE1_HUMAN
NC score	0.140190 (rank : 60)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	64	Shared Neighborhood Hits	37
SwissProt Accessions	P05976	Gene names	MYL1
Domain Architecture
Description	Myosin light chain 1, skeletal muscle isoform (MLC1F) (A1 catalytic) (Alkali myosin light chain 1).

MLE3_HUMAN
NC score	0.136870 (rank : 61)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	60	Shared Neighborhood Hits	35
SwissProt Accessions	P06741	Gene names	MYL1
Domain Architecture
Description	Myosin light chain 3, skeletal muscle isoform (A2 catalytic) (Alkali myosin light chain 3) (MLC3F).

EFHB_HUMAN
NC score	0.136315 (rank : 62)	θ value	0.0961366 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	125	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N7U6, Q6ZWK9, Q8IV58, Q96LQ6	Gene names	EFHB
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

MYL3_MOUSE
NC score	0.132781 (rank : 63)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	98	Target Neighborhood Hits	70	Shared Neighborhood Hits	37
SwissProt Accessions	P09542, Q3UIF4, Q9CQZ2	Gene names	Myl3, Mlc1v, Mylc
Domain Architecture
Description	Myosin light polypeptide 3 (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain).

PRVA_MOUSE
NC score	0.131508 (rank : 64)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	98	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	P32848	Gene names	Pvalb, Pva
Domain Architecture
Description	Parvalbumin alpha.

MYL3_HUMAN
NC score	0.129338 (rank : 65)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	98	Target Neighborhood Hits	66	Shared Neighborhood Hits	37
SwissProt Accessions	P08590, Q9NRS8	Gene names	MYL3
Domain Architecture
Description	Myosin light polypeptide 3 (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain) (Cardiac myosin light chain-1) (CMLC1).

MYL4_HUMAN
NC score	0.126045 (rank : 66)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	98	Target Neighborhood Hits	66	Shared Neighborhood Hits	36
SwissProt Accessions	P12829, P11783	Gene names	MYL4, MLC1
Domain Architecture
Description	Myosin light polypeptide 4 (Myosin light chain 1, embryonic muscle/atrial isoform) (Myosin light chain alkali, GT-1 isoform).

MYL4_MOUSE
NC score	0.125854 (rank : 67)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	98	Target Neighborhood Hits	63	Shared Neighborhood Hits	38
SwissProt Accessions	P09541	Gene names	Myl4, Mlc1a, Myla
Domain Architecture
Description	Myosin light polypeptide 4 (Myosin light chain 1, atrial/fetal isoform) (MLC1A) (MLC1EMB).

PRVA_HUMAN
NC score	0.117191 (rank : 68)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	98	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	P20472, P78378, Q4VB78, Q5R3Q9	Gene names	PVALB
Domain Architecture	No domain graphic available
Description	Parvalbumin alpha.

ACTN2_HUMAN
NC score	0.111031 (rank : 69)	θ value	0.0736092 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	295	Shared Neighborhood Hits	48
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN2_MOUSE
NC score	0.110295 (rank : 70)	θ value	0.0736092 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	287	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

CHP2_MOUSE
NC score	0.104584 (rank : 71)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	98	Target Neighborhood Hits	122	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D869	Gene names	Chp2, Hca520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520 homolog).

CHP2_HUMAN
NC score	0.102662 (rank : 72)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	98	Target Neighborhood Hits	122	Shared Neighborhood Hits	43
SwissProt Accessions	O43745	Gene names	CHP2, HCA520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520).

CHP1_MOUSE
NC score	0.102099 (rank : 73)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	98	Target Neighborhood Hits	117	Shared Neighborhood Hits	43
SwissProt Accessions	P61022, Q62877, Q6ZWQ8	Gene names	Chp, Sid470
Domain Architecture
Description	Calcium-binding protein p22 (Calcium-binding protein CHP) (Calcineurin homologous protein) (Sid 470).

CHP1_HUMAN
NC score	0.100817 (rank : 74)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	98	Target Neighborhood Hits	114	Shared Neighborhood Hits	45
SwissProt Accessions	Q99653	Gene names	CHP
Domain Architecture
Description	Calcium-binding protein p22 (Calcium-binding protein CHP) (Calcineurin homologous protein) (Calcineurin B homolog).

EFHD1_MOUSE
NC score	0.099435 (rank : 75)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	98	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D4J1, Q543U4	Gene names	Efhd1, Sws2
Domain Architecture
Description	EF-hand domain-containing protein 1 (Swiprosin-2).

EFHD1_HUMAN
NC score	0.099287 (rank : 76)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	98	Target Neighborhood Hits	108	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BUP0, Q9BTF8, Q9H8I2, Q9HBQ0	Gene names	EFHD1, SWS2
Domain Architecture
Description	EF-hand domain-containing protein 1 (Swiprosin-2).

ACTN3_MOUSE
NC score	0.095899 (rank : 77)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	265	Shared Neighborhood Hits	45
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN3_HUMAN
NC score	0.094010 (rank : 78)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	272	Shared Neighborhood Hits	44
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

MACF4_HUMAN
NC score	0.093884 (rank : 79)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	1321	Shared Neighborhood Hits	66
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

CALB2_MOUSE
NC score	0.093676 (rank : 80)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	98	Target Neighborhood Hits	141	Shared Neighborhood Hits	49
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

BPA1_MOUSE
NC score	0.092823 (rank : 81)	θ value	0.0113563 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	1477	Shared Neighborhood Hits	64
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MACF1_MOUSE
NC score	0.091453 (rank : 82)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	1313	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

BPAEA_HUMAN
NC score	0.091292 (rank : 83)	θ value	0.279714 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	1369	Shared Neighborhood Hits	69
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CALB2_HUMAN
NC score	0.090756 (rank : 84)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	98	Target Neighborhood Hits	149	Shared Neighborhood Hits	50
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

MACF1_HUMAN
NC score	0.090649 (rank : 85)	θ value	0.21417 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	1341	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

EFHB_MOUSE
NC score	0.090508 (rank : 86)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	120	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CDU5	Gene names	Efhb
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

KIP2_HUMAN
NC score	0.088650 (rank : 87)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	98	Target Neighborhood Hits	107	Shared Neighborhood Hits	40
SwissProt Accessions	O75838	Gene names	CIB2, KIP2
Domain Architecture	No domain graphic available
Description	Calcium and integrin-binding protein 2 (Kinase-interacting protein 2) (KIP 2).

KIP2_MOUSE
NC score	0.087878 (rank : 88)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	98	Target Neighborhood Hits	110	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z309	Gene names	Cib2, Kip2
Domain Architecture	No domain graphic available
Description	Calcium and integrin-binding protein 2 (Kinase-interacting protein 2) (KIP 2).

ACTN1_HUMAN
NC score	0.087294 (rank : 89)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	98	Target Neighborhood Hits	221	Shared Neighborhood Hits	42
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN1_MOUSE
NC score	0.086324 (rank : 90)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	98	Target Neighborhood Hits	216	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN4_HUMAN
NC score	0.085414 (rank : 91)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	98	Target Neighborhood Hits	279	Shared Neighborhood Hits	44
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

GUC1A_MOUSE
NC score	0.084911 (rank : 92)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	152	Shared Neighborhood Hits	48
SwissProt Accessions	P43081	Gene names	Guca1a, Gcap, Gcap1, Guca1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

ACTN4_MOUSE
NC score	0.084379 (rank : 93)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	98	Target Neighborhood Hits	276	Shared Neighborhood Hits	44
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

EFHD2_MOUSE
NC score	0.083242 (rank : 94)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	98	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D8Y0, Q9D0P4	Gene names	Efhd2, Sws1
Domain Architecture
Description	EF-hand domain-containing protein 2 (Swiprosin-1).

EFHD2_HUMAN
NC score	0.082533 (rank : 95)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	98	Target Neighborhood Hits	86	Shared Neighborhood Hits	31
SwissProt Accessions	Q96C19	Gene names	EFHD2, SWS1
Domain Architecture
Description	EF-hand domain-containing protein 2 (Swiprosin-1).

GUC1C_HUMAN
NC score	0.081953 (rank : 96)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	98	Target Neighborhood Hits	148	Shared Neighborhood Hits	41
SwissProt Accessions	O95843, O95844, Q9UNM0	Gene names	GUCA1C, GCAP3
Domain Architecture
Description	Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C).

NCALD_HUMAN
NC score	0.081656 (rank : 97)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	153	Shared Neighborhood Hits	47
SwissProt Accessions	P61601, P29554, Q8IYC3, Q9H0W2	Gene names	NCALD
Domain Architecture
Description	Neurocalcin delta.

NCALD_MOUSE
NC score	0.081656 (rank : 98)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	153	Shared Neighborhood Hits	47
SwissProt Accessions	Q91X97, Q3TJS9, Q8BZN9	Gene names	Ncald, D15Ertd412e
Domain Architecture
Description	Neurocalcin delta.

GPDM_HUMAN
NC score	0.080822 (rank : 99)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	98	Target Neighborhood Hits	116	Shared Neighborhood Hits	34
SwissProt Accessions	P43304, Q59FR1, Q9HAP9	Gene names	GPD2
Domain Architecture
Description	Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M) (mtGPD).

PLSI_HUMAN
NC score	0.080608 (rank : 100)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	98	Target Neighborhood Hits	209	Shared Neighborhood Hits	48
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

SPTA2_HUMAN
NC score	0.079956 (rank : 101)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	98	Target Neighborhood Hits	888	Shared Neighborhood Hits	58
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

PLSL_MOUSE
NC score	0.079646 (rank : 102)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	98	Target Neighborhood Hits	170	Shared Neighborhood Hits	43
SwissProt Accessions	Q61233, Q3UE24, Q8R1X3, Q9CV77	Gene names	Lcp1, Pls2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (pp65).

CALB1_MOUSE
NC score	0.079536 (rank : 103)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	98	Target Neighborhood Hits	129	Shared Neighborhood Hits	46
SwissProt Accessions	P12658, Q545N6	Gene names	Calb1
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K) (Spot 35 protein) (PCD-29).

GUC1A_HUMAN
NC score	0.078888 (rank : 104)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	98	Target Neighborhood Hits	147	Shared Neighborhood Hits	46
SwissProt Accessions	P43080, Q9NU14	Gene names	GUCA1A, GCAP, GCAP1, GUCA1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

CALB1_HUMAN
NC score	0.078832 (rank : 105)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	98	Target Neighborhood Hits	130	Shared Neighborhood Hits	45
SwissProt Accessions	P05937	Gene names	CALB1, CAB27
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K).

GPDM_MOUSE
NC score	0.078691 (rank : 106)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	98	Target Neighborhood Hits	101	Shared Neighborhood Hits	29
SwissProt Accessions	Q64521, Q61507	Gene names	Gpd2, Gdm1
Domain Architecture
Description	Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M).

PLSL_HUMAN
NC score	0.078421 (rank : 107)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	98	Target Neighborhood Hits	168	Shared Neighborhood Hits	43
SwissProt Accessions	P13796	Gene names	LCP1, PLS2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P).

GUC1B_HUMAN
NC score	0.077882 (rank : 108)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	124	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UMX6, Q9NU15	Gene names	GUCA1B, GCAP2
Domain Architecture
Description	Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B).

KIP3_HUMAN
NC score	0.077101 (rank : 109)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	98	Target Neighborhood Hits	83	Shared Neighborhood Hits	31
SwissProt Accessions	Q96Q77	Gene names	CIB3, KIP3
Domain Architecture
Description	Calcium and integrin-binding protein 3 (Kinase-interacting protein 3) (KIP 3).

HPCL1_HUMAN
NC score	0.076545 (rank : 110)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	98	Target Neighborhood Hits	150	Shared Neighborhood Hits	47
SwissProt Accessions	P37235, Q969S5	Gene names	HPCAL1, BDR1
Domain Architecture
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Calcium-binding protein BDR-1) (HLP2).

EFCB3_MOUSE
NC score	0.076322 (rank : 111)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	98	Target Neighborhood Hits	65	Shared Neighborhood Hits	30
SwissProt Accessions	Q80X60	Gene names	Efcab3
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 3.

EFCB1_MOUSE
NC score	0.075784 (rank : 112)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	98	Target Neighborhood Hits	126	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D3N2, Q8BSW3, Q8C982, Q8CAI0, Q9D527, Q9D5E7	Gene names	Efcab1
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 1.

VISL1_HUMAN
NC score	0.075605 (rank : 113)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	124	Shared Neighborhood Hits	45
SwissProt Accessions	P62760, P28677, P29103, P42323, Q9UM20	Gene names	VSNL1, VISL1
Domain Architecture	No domain graphic available
Description	Visinin-like protein 1 (VILIP) (Hippocalcin-like protein 3) (HLP3).

VISL1_MOUSE
NC score	0.075605 (rank : 114)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	124	Shared Neighborhood Hits	45
SwissProt Accessions	P62761, P28677, P29103, P42323, Q9UM20	Gene names	Vsnl1, Visl1
Domain Architecture	No domain graphic available
Description	Visinin-like protein 1 (VILIP) (Neural visinin-like protein 1) (NVL-1) (NVP-1).

KIP1_HUMAN
NC score	0.074845 (rank : 115)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	98	Target Neighborhood Hits	105	Shared Neighborhood Hits	38
SwissProt Accessions	Q99828, O00693, O00735, Q6IB49, Q96J54, Q99971	Gene names	CIB1, CIB, KIP, PRKDCIP
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB) (SNK- interacting protein 2-28) (SIP2-28).

KIP1_MOUSE
NC score	0.074379 (rank : 116)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	98	Target Neighborhood Hits	109	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z0F4, Q3TN80	Gene names	Cib1, Cib, Kip, Prkdcip
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB).

HPCL1_MOUSE
NC score	0.074045 (rank : 117)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	98	Target Neighborhood Hits	149	Shared Neighborhood Hits	48
SwissProt Accessions	P62748, P35333	Gene names	Hpcal1
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Neural visinin-like protein 3) (NVL-3) (NVP-3).

HPCA_HUMAN
NC score	0.073409 (rank : 118)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	98	Target Neighborhood Hits	156	Shared Neighborhood Hits	49
SwissProt Accessions	P84074, P32076, P41211, P70510	Gene names	HPCA, BDR2
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2).

HPCA_MOUSE
NC score	0.073409 (rank : 119)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	98	Target Neighborhood Hits	156	Shared Neighborhood Hits	49
SwissProt Accessions	P84075, P32076, P41211, P70510	Gene names	Hpca
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin.

EFCB3_HUMAN
NC score	0.073340 (rank : 120)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	98	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N7B9	Gene names	EFCAB3
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 3.

SORCN_HUMAN
NC score	0.071456 (rank : 121)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	98	Target Neighborhood Hits	82	Shared Neighborhood Hits	37
SwissProt Accessions	P30626	Gene names	SRI
Domain Architecture
Description	Sorcin (22 kDa protein) (CP-22) (V19).

HPCL4_HUMAN
NC score	0.071451 (rank : 122)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	98	Target Neighborhood Hits	123	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UM19, Q5TG97, Q8N611	Gene names	HPCAL4
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 4 (HLP4).

HPCL4_MOUSE
NC score	0.071449 (rank : 123)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	98	Target Neighborhood Hits	123	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BGZ1	Gene names	Hpcal4
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 4 (Neural visinin-like protein 2) (NVP-2).

DUOX1_HUMAN
NC score	0.070380 (rank : 124)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	172	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NRD9, Q6ZMB3, Q6ZR09, Q9NZC1	Gene names	DUOX1, DUOX, LNOX1, THOX1
Domain Architecture	No domain graphic available
Description	Dual oxidase 1 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH thyroid oxidase 1) (Thyroid oxidase 1) (Large NOX 1) (Long NOX 1).

PLST_HUMAN
NC score	0.069491 (rank : 125)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	98	Target Neighborhood Hits	161	Shared Neighborhood Hits	41
SwissProt Accessions	P13797, Q86YI6	Gene names	PLS3
Domain Architecture
Description	Plastin-3 (T-plastin).

EFCB1_HUMAN
NC score	0.069412 (rank : 126)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	98	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HAE3	Gene names	EFCAB1
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 1.

PLST_MOUSE
NC score	0.069012 (rank : 127)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	98	Target Neighborhood Hits	156	Shared Neighborhood Hits	42
SwissProt Accessions	Q99K51	Gene names	Pls3
Domain Architecture	No domain graphic available
Description	Plastin-3 (T-plastin).

AIF1_HUMAN
NC score	0.067657 (rank : 128)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	98	Target Neighborhood Hits	44	Shared Neighborhood Hits	25
SwissProt Accessions	P55008, Q9UKS9	Gene names	AIF1, G1, IBA1
Domain Architecture
Description	Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1).

AIF1_MOUSE
NC score	0.067191 (rank : 129)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	98	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	O70200	Gene names	Aif1, Iba1
Domain Architecture	No domain graphic available
Description	Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1).

GUC1B_MOUSE
NC score	0.064950 (rank : 130)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	98	Target Neighborhood Hits	116	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VBV8	Gene names	Guca1b
Domain Architecture	No domain graphic available
Description	Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B).

IBA2_MOUSE
NC score	0.063884 (rank : 131)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	98	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQX4, Q8C150	Gene names	Iba2
Domain Architecture	No domain graphic available
Description	Ionized calcium-binding adapter molecule 2.

RCN2_MOUSE
NC score	0.062966 (rank : 132)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	98	Target Neighborhood Hits	108	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BP92, O70341	Gene names	Rcn2
Domain Architecture	No domain graphic available
Description	Reticulocalbin-2 precursor (Taipoxin-associated calcium-binding protein 49) (TCBP-49).

IBA2_HUMAN
NC score	0.062905 (rank : 133)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	98	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BQI0, Q6ZR40, Q8NAX7, Q8WU47, Q9H9G0	Gene names	IBA2, C9orf58
Domain Architecture	No domain graphic available
Description	Ionized calcium-binding adapter molecule 2.

SORCN_MOUSE
NC score	0.062539 (rank : 134)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	98	Target Neighborhood Hits	72	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P069, Q3UKC5, Q9CR38, Q9D7V8	Gene names	Sri
Domain Architecture	No domain graphic available
Description	Sorcin.

PEF1_MOUSE
NC score	0.061272 (rank : 135)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	98	Target Neighborhood Hits	112	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BFY6, Q8VCT5, Q9CYW8, Q9D934	Gene names	Pef1
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

GRAN_HUMAN
NC score	0.060948 (rank : 136)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	98	Target Neighborhood Hits	57	Shared Neighborhood Hits	28
SwissProt Accessions	P28676	Gene names	GCA, GCL
Domain Architecture
Description	Grancalcin.

AYTL1_HUMAN
NC score	0.059861 (rank : 137)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	98	Target Neighborhood Hits	140	Shared Neighborhood Hits	44
SwissProt Accessions	Q7L5N7, Q6MZJ6, Q9NX23	Gene names	AYTL1
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1 (EC 2.3.1.-).

PEF1_HUMAN
NC score	0.059109 (rank : 138)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	98	Target Neighborhood Hits	135	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

NCS1_HUMAN
NC score	0.058788 (rank : 139)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	98	Target Neighborhood Hits	132	Shared Neighborhood Hits	39
SwissProt Accessions	P62166, P36610, Q9UK26	Gene names	FREQ, FLUP, NCS1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein).

NCS1_MOUSE
NC score	0.058788 (rank : 140)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	98	Target Neighborhood Hits	132	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BNY6	Gene names	Freq, Ncs1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog).

PPE2_MOUSE
NC score	0.058201 (rank : 141)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	112	Shared Neighborhood Hits	34
SwissProt Accessions	O35385	Gene names	Ppef2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

MCFD2_HUMAN
NC score	0.057786 (rank : 142)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	62	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NI22, Q8N3M5	Gene names	MCFD2, SDNSF
Domain Architecture
Description	Multiple coagulation factor deficiency protein 2 precursor (Neural stem cell-derived neuronal survival protein).

RCN2_HUMAN
NC score	0.057520 (rank : 143)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	98	Target Neighborhood Hits	95	Shared Neighborhood Hits	39
SwissProt Accessions	Q14257	Gene names	RCN2, ERC55
Domain Architecture
Description	Reticulocalbin-2 precursor (Calcium-binding protein ERC-55) (E6- binding protein) (E6BP).

AYT1A_MOUSE
NC score	0.057397 (rank : 144)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	98	Target Neighborhood Hits	126	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BYI6	Gene names	Aytl1a, Aytl1
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1-A (EC 2.3.1.-).

CSEN_HUMAN
NC score	0.055887 (rank : 145)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	98	Target Neighborhood Hits	128	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y2W7, Q53TJ5, Q96T40, Q9UJ84, Q9UJ85	Gene names	KCNIP3, CSEN, DREAM, KCHIP3
Domain Architecture
Description	Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3) (A-type potassium channel modulatory protein 3).

RECO_MOUSE
NC score	0.055635 (rank : 146)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	98	Target Neighborhood Hits	108	Shared Neighborhood Hits	34
SwissProt Accessions	P34057	Gene names	Rcvrn, Rcv1
Domain Architecture
Description	Recoverin (Cancer-associated retinopathy protein) (Protein CAR) (23 kDa photoreceptor cell-specific protein).

KCIP4_HUMAN
NC score	0.055325 (rank : 147)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	98	Target Neighborhood Hits	136	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PIL6, Q4W5G8, Q8NEU0, Q9BWT2, Q9H294, Q9H2A4	Gene names	KCNIP4, CALP, KCHIP4
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Potassium channel-interacting protein 4) (Calsenilin-like protein).

KCIP4_MOUSE
NC score	0.055311 (rank : 148)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	98	Target Neighborhood Hits	136	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PHZ8, Q6DTJ3, Q8CAD0, Q8R4I2, Q9EQ01	Gene names	Kcnip4, Calp, Kchip4
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Potassium channel-interacting protein 4) (Calsenilin-like protein).

DUOX2_HUMAN
NC score	0.055269 (rank : 149)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	98	Target Neighborhood Hits	139	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NRD8, Q9NR02, Q9UHF9	Gene names	DUOX2, LNOX2, THOX2
Domain Architecture	No domain graphic available
Description	Dual oxidase 2 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Thyroid oxidase 2) (NADH/NADPH thyroid oxidase p138-tox) (p138 thyroid oxidase) (Large NOX 2) (Long NOX 2).

EFHC1_MOUSE
NC score	0.053701 (rank : 150)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	65	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D9T8	Gene names	Efhc1
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing protein 1.

SEGN_HUMAN
NC score	0.053495 (rank : 151)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	98	Target Neighborhood Hits	96	Shared Neighborhood Hits	29
SwissProt Accessions	O76038, Q5VV44, Q96QV7, Q9UJF6	Gene names	SCGN, SECRET
Domain Architecture
Description	Secretagogin.

CSEN_MOUSE
NC score	0.051869 (rank : 152)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	98	Target Neighborhood Hits	117	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QXT8, Q924L0, Q99PH9, Q99PI0, Q99PI2, Q99PI3, Q9JHZ5	Gene names	Kcnip3, Csen, Dream, Kchip3
Domain Architecture
Description	Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (A-type potassium channel modulatory protein 3) (KChIP3).

CPNS2_HUMAN
NC score	0.051751 (rank : 153)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	98	Target Neighborhood Hits	66	Shared Neighborhood Hits	29
SwissProt Accessions	Q96L46, Q9BPV4	Gene names	CAPNS2
Domain Architecture
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

RECO_HUMAN
NC score	0.051464 (rank : 154)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	98	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	P35243	Gene names	RCVRN, RCV1
Domain Architecture
Description	Recoverin (Cancer-associated retinopathy protein) (Protein CAR).

TNNT3_MOUSE
NC score	0.050430 (rank : 155)	θ value	0.163984 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	317	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

MCFD2_MOUSE
NC score	0.049297 (rank : 156)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	61	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K5B2, Q3U9G5	Gene names	Mcfd2, Sdnsf
Domain Architecture
Description	Multiple coagulation factor deficiency protein 2 homolog precursor (Neural stem cell-derived neuronal survival protein).

RBCC1_MOUSE
NC score	0.044881 (rank : 157)	θ value	0.0330416 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	1048	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

NOC3L_HUMAN
NC score	0.042524 (rank : 158)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	135	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WTT2, Q9H5M6, Q9H9D8	Gene names	NOC3L, AD24, C10orf117, FAD24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

YLPM1_HUMAN
NC score	0.038610 (rank : 159)	θ value	0.365318 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	670	Shared Neighborhood Hits	3
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

RPGR1_HUMAN
NC score	0.037311 (rank : 160)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	578	Shared Neighborhood Hits	16
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RYR2_HUMAN
NC score	0.035376 (rank : 161)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	175	Shared Neighborhood Hits	25
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

CCD11_HUMAN
NC score	0.034513 (rank : 162)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	822	Shared Neighborhood Hits	22
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

PLCB3_HUMAN
NC score	0.032604 (rank : 163)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	445	Shared Neighborhood Hits	14
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

NOC3L_MOUSE
NC score	0.031463 (rank : 164)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	177	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VI84, Q9JKM3	Gene names	Noc3l, Ad24, Fad24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

GOGA4_MOUSE
NC score	0.030742 (rank : 165)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	1939	Shared Neighborhood Hits	28
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

PLCB3_MOUSE
NC score	0.030391 (rank : 166)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	344	Shared Neighborhood Hits	10
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

LZTS1_HUMAN
NC score	0.030216 (rank : 167)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	532	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

SEL1L_HUMAN
NC score	0.029895 (rank : 168)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBV2, Q6UWT6, Q9P1T9, Q9UHK7	Gene names	SEL1L, TSA305
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

SEL1L_MOUSE
NC score	0.029759 (rank : 169)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2G6, Q9DBD8	Gene names	Sel1l, Sel1h
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

ANR12_HUMAN
NC score	0.029612 (rank : 170)	θ value	0.163984 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	1081	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

KTN1_HUMAN
NC score	0.028416 (rank : 171)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	1197	Shared Neighborhood Hits	19
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

TXLNB_MOUSE
NC score	0.026879 (rank : 172)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	640	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

HELZ_HUMAN
NC score	0.022761 (rank : 173)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	198	Shared Neighborhood Hits	4
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

ITIH4_HUMAN
NC score	0.022343 (rank : 174)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q14624, Q15135, Q9P190, Q9UQ54	Gene names	ITIH4, IHRP, ITIHL1, PK120
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H4 precursor (ITI heavy chain H4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (PK-120) (GP120) [Contains: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha- trypsin inhibitor heavy chain H4].

MCES_MOUSE
NC score	0.021690 (rank : 175)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D0L8, Q3V3U9, Q6ZQC6, Q9D5F1	Gene names	Rnmt, Kiaa0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase).

BAZ1B_MOUSE
NC score	0.020975 (rank : 176)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	394	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

RYR1_HUMAN
NC score	0.020401 (rank : 177)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	303	Shared Neighborhood Hits	5
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

KI21B_MOUSE
NC score	0.020274 (rank : 178)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	997	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

ATRX_HUMAN
NC score	0.020228 (rank : 179)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	842	Shared Neighborhood Hits	11
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

KI21A_MOUSE
NC score	0.017461 (rank : 180)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	1317	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

KCNH7_HUMAN
NC score	0.009864 (rank : 181)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

ROCK2_MOUSE
NC score	0.007709 (rank : 182)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	2072	Shared Neighborhood Hits	22
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

DHX36_MOUSE
NC score	0.005672 (rank : 183)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

ZBTB1_HUMAN
NC score	0.001528 (rank : 184)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	805	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2K1, Q86SW8	Gene names	ZBTB1, KIAA0997
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 1.

ZBTB1_MOUSE
NC score	0.001076 (rank : 185)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	795	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VL9, Q8CDP7, Q99LD2	Gene names	Zbtb1
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 1.