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Network neighborhood for query Sequence : KCNH7_HUMAN

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KCNH7_HUMAN
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KCNH2_HUMAN
θ value	0 (rank : 1)	NC score	0.988809 (rank : 4)
Query Neighborhood Hits	107	Target Neighborhood Hits	158	Shared Neighborhood Hits	71
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
θ value	0 (rank : 2)	NC score	0.989176 (rank : 3)
Query Neighborhood Hits	107	Target Neighborhood Hits	165	Shared Neighborhood Hits	72
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH6_HUMAN
θ value	0 (rank : 3)	NC score	0.979920 (rank : 5)
Query Neighborhood Hits	107	Target Neighborhood Hits	222	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH7_HUMAN
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	107	Target Neighborhood Hits	107	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH7_MOUSE
θ value	0 (rank : 5)	NC score	0.998417 (rank : 2)
Query Neighborhood Hits	107	Target Neighborhood Hits	98	Shared Neighborhood Hits	84
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH8_HUMAN
θ value	1.99884e-124 (rank : 6)	NC score	0.959333 (rank : 6)
Query Neighborhood Hits	107	Target Neighborhood Hits	104	Shared Neighborhood Hits	59
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH4_HUMAN
θ value	3.1986e-114 (rank : 7)	NC score	0.954927 (rank : 7)
Query Neighborhood Hits	107	Target Neighborhood Hits	177	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH5_HUMAN
θ value	1.21547e-113 (rank : 8)	NC score	0.951974 (rank : 9)
Query Neighborhood Hits	107	Target Neighborhood Hits	99	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH5_MOUSE
θ value	2.70778e-113 (rank : 9)	NC score	0.951989 (rank : 8)
Query Neighborhood Hits	107	Target Neighborhood Hits	102	Shared Neighborhood Hits	62
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH1_HUMAN
θ value	1.13764e-111 (rank : 10)	NC score	0.951434 (rank : 11)
Query Neighborhood Hits	107	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH1_MOUSE
θ value	1.94052e-111 (rank : 11)	NC score	0.951497 (rank : 10)
Query Neighborhood Hits	107	Target Neighborhood Hits	94	Shared Neighborhood Hits	61
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH3_MOUSE
θ value	2.71407e-105 (rank : 12)	NC score	0.948987 (rank : 12)
Query Neighborhood Hits	107	Target Neighborhood Hits	133	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH3_HUMAN
θ value	3.54468e-105 (rank : 13)	NC score	0.948978 (rank : 13)
Query Neighborhood Hits	107	Target Neighborhood Hits	148	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

HCN4_HUMAN
θ value	3.73686e-38 (rank : 14)	NC score	0.783640 (rank : 24)
Query Neighborhood Hits	107	Target Neighborhood Hits	303	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN2_MOUSE
θ value	9.20422e-37 (rank : 15)	NC score	0.786764 (rank : 23)
Query Neighborhood Hits	107	Target Neighborhood Hits	278	Shared Neighborhood Hits	43
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN2_HUMAN
θ value	1.57e-36 (rank : 16)	NC score	0.778376 (rank : 26)
Query Neighborhood Hits	107	Target Neighborhood Hits	369	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN4_MOUSE
θ value	4.568e-36 (rank : 17)	NC score	0.781018 (rank : 25)
Query Neighborhood Hits	107	Target Neighborhood Hits	284	Shared Neighborhood Hits	39
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

CNGA2_MOUSE
θ value	5.96599e-36 (rank : 18)	NC score	0.819432 (rank : 14)
Query Neighborhood Hits	107	Target Neighborhood Hits	86	Shared Neighborhood Hits	44
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

HCN1_HUMAN
θ value	5.96599e-36 (rank : 19)	NC score	0.802843 (rank : 19)
Query Neighborhood Hits	107	Target Neighborhood Hits	120	Shared Neighborhood Hits	41
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
θ value	5.96599e-36 (rank : 20)	NC score	0.799298 (rank : 20)
Query Neighborhood Hits	107	Target Neighborhood Hits	172	Shared Neighborhood Hits	44
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

CNGA1_HUMAN
θ value	2.96089e-35 (rank : 21)	NC score	0.809367 (rank : 15)
Query Neighborhood Hits	107	Target Neighborhood Hits	149	Shared Neighborhood Hits	42
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
θ value	7.29293e-34 (rank : 22)	NC score	0.804020 (rank : 18)
Query Neighborhood Hits	107	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

HCN3_MOUSE
θ value	3.06405e-32 (rank : 23)	NC score	0.797947 (rank : 21)
Query Neighborhood Hits	107	Target Neighborhood Hits	112	Shared Neighborhood Hits	37
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN3_HUMAN
θ value	8.91499e-32 (rank : 24)	NC score	0.797655 (rank : 22)
Query Neighborhood Hits	107	Target Neighborhood Hits	99	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

CNGA3_MOUSE
θ value	1.52067e-31 (rank : 25)	NC score	0.807371 (rank : 16)
Query Neighborhood Hits	107	Target Neighborhood Hits	84	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
θ value	2.19584e-30 (rank : 26)	NC score	0.804196 (rank : 17)
Query Neighborhood Hits	107	Target Neighborhood Hits	125	Shared Neighborhood Hits	41
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGB3_HUMAN
θ value	1.47631e-18 (rank : 27)	NC score	0.733286 (rank : 28)
Query Neighborhood Hits	107	Target Neighborhood Hits	206	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_MOUSE
θ value	4.29542e-18 (rank : 28)	NC score	0.747367 (rank : 27)
Query Neighborhood Hits	107	Target Neighborhood Hits	74	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB1_HUMAN
θ value	2.35696e-16 (rank : 29)	NC score	0.724889 (rank : 29)
Query Neighborhood Hits	107	Target Neighborhood Hits	222	Shared Neighborhood Hits	41
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNKH_HUMAN
θ value	0.000786445 (rank : 30)	NC score	0.256148 (rank : 30)
Query Neighborhood Hits	107	Target Neighborhood Hits	89	Shared Neighborhood Hits	50
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

CP135_MOUSE
θ value	0.00228821 (rank : 31)	NC score	0.009249 (rank : 93)
Query Neighborhood Hits	107	Target Neighborhood Hits	1278	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

KCNQ3_MOUSE
θ value	0.00869519 (rank : 32)	NC score	0.076963 (rank : 57)
Query Neighborhood Hits	107	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNK2_HUMAN
θ value	0.0113563 (rank : 33)	NC score	0.190917 (rank : 32)
Query Neighborhood Hits	107	Target Neighborhood Hits	86	Shared Neighborhood Hits	50
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	0.0113563 (rank : 34)	NC score	0.190278 (rank : 33)
Query Neighborhood Hits	107	Target Neighborhood Hits	88	Shared Neighborhood Hits	50
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNKF_HUMAN
θ value	0.0113563 (rank : 35)	NC score	0.194678 (rank : 31)
Query Neighborhood Hits	107	Target Neighborhood Hits	87	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNQ3_HUMAN
θ value	0.0113563 (rank : 36)	NC score	0.074978 (rank : 59)
Query Neighborhood Hits	107	Target Neighborhood Hits	114	Shared Neighborhood Hits	44
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNK3_MOUSE
θ value	0.0431538 (rank : 37)	NC score	0.179053 (rank : 37)
Query Neighborhood Hits	107	Target Neighborhood Hits	93	Shared Neighborhood Hits	50
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KAP0_MOUSE
θ value	0.0563607 (rank : 38)	NC score	0.157688 (rank : 42)
Query Neighborhood Hits	107	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KCNK6_HUMAN
θ value	0.0563607 (rank : 39)	NC score	0.181656 (rank : 35)
Query Neighborhood Hits	107	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNKA_HUMAN
θ value	0.0563607 (rank : 40)	NC score	0.180640 (rank : 36)
Query Neighborhood Hits	107	Target Neighborhood Hits	111	Shared Neighborhood Hits	51
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNKG_HUMAN
θ value	0.0736092 (rank : 41)	NC score	0.170927 (rank : 38)
Query Neighborhood Hits	107	Target Neighborhood Hits	90	Shared Neighborhood Hits	48
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KAP0_HUMAN
θ value	0.0961366 (rank : 42)	NC score	0.168648 (rank : 40)
Query Neighborhood Hits	107	Target Neighborhood Hits	52	Shared Neighborhood Hits	33
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KCNK3_HUMAN
θ value	0.0961366 (rank : 43)	NC score	0.182007 (rank : 34)
Query Neighborhood Hits	107	Target Neighborhood Hits	88	Shared Neighborhood Hits	50
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KAP1_HUMAN
θ value	0.125558 (rank : 44)	NC score	0.145024 (rank : 45)
Query Neighborhood Hits	107	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
θ value	0.125558 (rank : 45)	NC score	0.142782 (rank : 46)
Query Neighborhood Hits	107	Target Neighborhood Hits	49	Shared Neighborhood Hits	31
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

GOGA1_MOUSE
θ value	0.279714 (rank : 46)	NC score	0.011603 (rank : 89)
Query Neighborhood Hits	107	Target Neighborhood Hits	994	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

KCNK4_HUMAN
θ value	0.279714 (rank : 47)	NC score	0.168897 (rank : 39)
Query Neighborhood Hits	107	Target Neighborhood Hits	109	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK4_MOUSE
θ value	0.279714 (rank : 48)	NC score	0.158648 (rank : 41)
Query Neighborhood Hits	107	Target Neighborhood Hits	118	Shared Neighborhood Hits	46
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KGP1A_HUMAN
θ value	0.365318 (rank : 49)	NC score	0.045671 (rank : 75)
Query Neighborhood Hits	107	Target Neighborhood Hits	901	Shared Neighborhood Hits	42
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	0.365318 (rank : 50)	NC score	0.045699 (rank : 74)
Query Neighborhood Hits	107	Target Neighborhood Hits	921	Shared Neighborhood Hits	42
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_MOUSE
θ value	0.365318 (rank : 51)	NC score	0.045287 (rank : 76)
Query Neighborhood Hits	107	Target Neighborhood Hits	922	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KCNQ2_HUMAN
θ value	0.47712 (rank : 52)	NC score	0.057541 (rank : 70)
Query Neighborhood Hits	107	Target Neighborhood Hits	114	Shared Neighborhood Hits	44
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
θ value	0.47712 (rank : 53)	NC score	0.056516 (rank : 71)
Query Neighborhood Hits	107	Target Neighborhood Hits	163	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCND1_MOUSE
θ value	0.62314 (rank : 54)	NC score	0.068476 (rank : 61)
Query Neighborhood Hits	107	Target Neighborhood Hits	165	Shared Neighborhood Hits	50
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
θ value	0.813845 (rank : 55)	NC score	0.062906 (rank : 64)
Query Neighborhood Hits	107	Target Neighborhood Hits	160	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNK9_HUMAN
θ value	0.813845 (rank : 56)	NC score	0.152250 (rank : 44)
Query Neighborhood Hits	107	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK9_MOUSE
θ value	0.813845 (rank : 57)	NC score	0.152362 (rank : 43)
Query Neighborhood Hits	107	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCNKD_MOUSE
θ value	1.06291 (rank : 58)	NC score	0.105634 (rank : 50)
Query Neighborhood Hits	107	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

CCNF_MOUSE
θ value	1.38821 (rank : 59)	NC score	0.012273 (rank : 87)
Query Neighborhood Hits	107	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P51944, Q60797, Q60799	Gene names	Ccnf
Domain Architecture
Description	G2/mitotic-specific cyclin-F.

CEND1_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.009955 (rank : 91)
Query Neighborhood Hits	107	Target Neighborhood Hits	284	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CJ049_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.026129 (rank : 82)
Query Neighborhood Hits	107	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WVF2	Gene names	C10orf49
Domain Architecture	No domain graphic available
Description	Protein C10orf49 precursor.

KCND2_HUMAN
θ value	1.38821 (rank : 62)	NC score	0.060640 (rank : 65)
Query Neighborhood Hits	107	Target Neighborhood Hits	154	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	1.38821 (rank : 63)	NC score	0.060629 (rank : 66)
Query Neighborhood Hits	107	Target Neighborhood Hits	156	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

LEO1_HUMAN
θ value	1.38821 (rank : 64)	NC score	0.012112 (rank : 88)
Query Neighborhood Hits	107	Target Neighborhood Hits	958	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

KCNK1_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.130428 (rank : 48)
Query Neighborhood Hits	107	Target Neighborhood Hits	68	Shared Neighborhood Hits	43
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

MACOI_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.010155 (rank : 90)
Query Neighborhood Hits	107	Target Neighborhood Hits	650	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

RND1_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.007327 (rank : 97)
Query Neighborhood Hits	107	Target Neighborhood Hits	230	Shared Neighborhood Hits	4
SwissProt Accessions	Q92730	Gene names	RND1, RHO6
Domain Architecture
Description	Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1).

RPGF4_MOUSE
θ value	1.81305 (rank : 68)	NC score	0.048738 (rank : 73)
Query Neighborhood Hits	107	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

KCNK5_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.130560 (rank : 47)
Query Neighborhood Hits	107	Target Neighborhood Hits	102	Shared Neighborhood Hits	52
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

SLIK1_HUMAN
θ value	2.36792 (rank : 70)	NC score	0.006509 (rank : 98)
Query Neighborhood Hits	107	Target Neighborhood Hits	297	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PX8, Q5U5I6, Q96SF9	Gene names	SLITRK1, KIAA1910, LRRC12
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor (Leucine-rich repeat-containing protein 12).

SLIK1_MOUSE
θ value	2.36792 (rank : 71)	NC score	0.006439 (rank : 99)
Query Neighborhood Hits	107	Target Neighborhood Hits	333	Shared Neighborhood Hits	5
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

KCND3_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.057564 (rank : 69)
Query Neighborhood Hits	107	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	3.0926 (rank : 73)	NC score	0.057593 (rank : 68)
Query Neighborhood Hits	107	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNK1_MOUSE
θ value	3.0926 (rank : 74)	NC score	0.125791 (rank : 49)
Query Neighborhood Hits	107	Target Neighborhood Hits	70	Shared Neighborhood Hits	41
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

LRCH2_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.005122 (rank : 104)
Query Neighborhood Hits	107	Target Neighborhood Hits	315	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

MACOI_MOUSE
θ value	3.0926 (rank : 76)	NC score	0.009084 (rank : 94)
Query Neighborhood Hits	107	Target Neighborhood Hits	620	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

RND1_MOUSE
θ value	3.0926 (rank : 77)	NC score	0.006383 (rank : 100)
Query Neighborhood Hits	107	Target Neighborhood Hits	228	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BLR7, Q3TSQ9, Q80ZR7, Q8BYF2	Gene names	Rnd1, Rho6
Domain Architecture	No domain graphic available
Description	Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1).

RPGF4_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.044093 (rank : 77)
Query Neighborhood Hits	107	Target Neighborhood Hits	88	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

CAYP2_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.009864 (rank : 92)
Query Neighborhood Hits	107	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXY5, Q6PH84, Q8N242, Q8NAY5	Gene names	CAPS2
Domain Architecture
Description	Calcyphosin-2 (Calcyphosine-2).

HIP1_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.001122 (rank : 113)
Query Neighborhood Hits	107	Target Neighborhood Hits	1016	Shared Neighborhood Hits	10
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

KCMA1_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.063419 (rank : 63)
Query Neighborhood Hits	107	Target Neighborhood Hits	96	Shared Neighborhood Hits	40
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCMA1_MOUSE
θ value	4.03905 (rank : 82)	NC score	0.063537 (rank : 62)
Query Neighborhood Hits	107	Target Neighborhood Hits	94	Shared Neighborhood Hits	40
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCNKC_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.082680 (rank : 56)
Query Neighborhood Hits	107	Target Neighborhood Hits	51	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

KCNKD_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.084642 (rank : 55)
Query Neighborhood Hits	107	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

LIPB1_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.004665 (rank : 106)
Query Neighborhood Hits	107	Target Neighborhood Hits	640	Shared Neighborhood Hits	7
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

TEX14_MOUSE
θ value	5.27518 (rank : 86)	NC score	0.001394 (rank : 112)
Query Neighborhood Hits	107	Target Neighborhood Hits	1333	Shared Neighborhood Hits	15
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ABCAD_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.002911 (rank : 109)
Query Neighborhood Hits	107	Target Neighborhood Hits	150	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABTAP_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.005894 (rank : 101)
Query Neighborhood Hits	107	Target Neighborhood Hits	381	Shared Neighborhood Hits	6
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

DTNB_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.005333 (rank : 103)
Query Neighborhood Hits	107	Target Neighborhood Hits	263	Shared Neighborhood Hits	4
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

KCNA2_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.024586 (rank : 84)
Query Neighborhood Hits	107	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.025563 (rank : 83)
Query Neighborhood Hits	107	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNN4_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.038137 (rank : 78)
Query Neighborhood Hits	107	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

KGP2_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.033184 (rank : 80)
Query Neighborhood Hits	107	Target Neighborhood Hits	1023	Shared Neighborhood Hits	34
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

S14L4_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.004431 (rank : 107)
Query Neighborhood Hits	107	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UDX3	Gene names	SEC14L4, TAP3
Domain Architecture
Description	SEC14-like protein 4 (Tocopherol-associated protein 3).

CD2L7_HUMAN
θ value	8.99809 (rank : 95)	NC score	-0.004053 (rank : 114)
Query Neighborhood Hits	107	Target Neighborhood Hits	1275	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CLCA_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.005003 (rank : 105)
Query Neighborhood Hits	107	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	O08585	Gene names	Clta
Domain Architecture
Description	Clathrin light chain A (Lca).

KCNF1_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.027632 (rank : 81)
Query Neighborhood Hits	107	Target Neighborhood Hits	109	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNN4_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.035103 (rank : 79)
Query Neighborhood Hits	107	Target Neighborhood Hits	85	Shared Neighborhood Hits	41
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

KCNQ4_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.051006 (rank : 72)
Query Neighborhood Hits	107	Target Neighborhood Hits	136	Shared Neighborhood Hits	39
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

LIPB1_MOUSE
θ value	8.99809 (rank : 100)	NC score	0.002783 (rank : 110)
Query Neighborhood Hits	107	Target Neighborhood Hits	727	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

RFC1_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.003613 (rank : 108)
Query Neighborhood Hits	107	Target Neighborhood Hits	290	Shared Neighborhood Hits	2
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

SIA7A_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.008258 (rank : 95)
Query Neighborhood Hits	107	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

SRRM2_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.020524 (rank : 85)
Query Neighborhood Hits	107	Target Neighborhood Hits	1470	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

STON2_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.005416 (rank : 102)
Query Neighborhood Hits	107	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

TM119_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.013006 (rank : 86)
Query Neighborhood Hits	107	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q4V9L6, Q6UXE5, Q8N2F5	Gene names	TMEM119
Domain Architecture	No domain graphic available
Description	Transmembrane protein 119 precursor.

TPR_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.001970 (rank : 111)
Query Neighborhood Hits	107	Target Neighborhood Hits	1921	Shared Neighborhood Hits	23
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

URFB1_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.007593 (rank : 96)
Query Neighborhood Hits	107	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q6BDS2, Q9NXE0	Gene names	UHRF1BP1, C6orf107
Domain Architecture	No domain graphic available
Description	UHRF1-binding protein 1 (Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1) (ICBP90-binding protein 1).

CT152_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.071043 (rank : 60)
Query Neighborhood Hits	107	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KAP2_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.098571 (rank : 53)
Query Neighborhood Hits	107	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.100639 (rank : 52)
Query Neighborhood Hits	107	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.098228 (rank : 54)
Query Neighborhood Hits	107	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.101456 (rank : 51)
Query Neighborhood Hits	107	Target Neighborhood Hits	43	Shared Neighborhood Hits	26
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KCNK7_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.058142 (rank : 67)
Query Neighborhood Hits	107	Target Neighborhood Hits	42	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCNK7_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.075078 (rank : 58)
Query Neighborhood Hits	107	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

Hits sorted by NC score

KCNH7_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	107	Target Neighborhood Hits	107	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH7_MOUSE
NC score	0.998417 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	107	Target Neighborhood Hits	98	Shared Neighborhood Hits	84
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH2_MOUSE
NC score	0.989176 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	107	Target Neighborhood Hits	165	Shared Neighborhood Hits	72
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH2_HUMAN
NC score	0.988809 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	107	Target Neighborhood Hits	158	Shared Neighborhood Hits	71
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH6_HUMAN
NC score	0.979920 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	107	Target Neighborhood Hits	222	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH8_HUMAN
NC score	0.959333 (rank : 6)	θ value	1.99884e-124 (rank : 6)
Query Neighborhood Hits	107	Target Neighborhood Hits	104	Shared Neighborhood Hits	59
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH4_HUMAN
NC score	0.954927 (rank : 7)	θ value	3.1986e-114 (rank : 7)
Query Neighborhood Hits	107	Target Neighborhood Hits	177	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH5_MOUSE
NC score	0.951989 (rank : 8)	θ value	2.70778e-113 (rank : 9)
Query Neighborhood Hits	107	Target Neighborhood Hits	102	Shared Neighborhood Hits	62
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
NC score	0.951974 (rank : 9)	θ value	1.21547e-113 (rank : 8)
Query Neighborhood Hits	107	Target Neighborhood Hits	99	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH1_MOUSE
NC score	0.951497 (rank : 10)	θ value	1.94052e-111 (rank : 11)
Query Neighborhood Hits	107	Target Neighborhood Hits	94	Shared Neighborhood Hits	61
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.951434 (rank : 11)	θ value	1.13764e-111 (rank : 10)
Query Neighborhood Hits	107	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH3_MOUSE
NC score	0.948987 (rank : 12)	θ value	2.71407e-105 (rank : 12)
Query Neighborhood Hits	107	Target Neighborhood Hits	133	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH3_HUMAN
NC score	0.948978 (rank : 13)	θ value	3.54468e-105 (rank : 13)
Query Neighborhood Hits	107	Target Neighborhood Hits	148	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

CNGA2_MOUSE
NC score	0.819432 (rank : 14)	θ value	5.96599e-36 (rank : 18)
Query Neighborhood Hits	107	Target Neighborhood Hits	86	Shared Neighborhood Hits	44
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA1_HUMAN
NC score	0.809367 (rank : 15)	θ value	2.96089e-35 (rank : 21)
Query Neighborhood Hits	107	Target Neighborhood Hits	149	Shared Neighborhood Hits	42
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
NC score	0.807371 (rank : 16)	θ value	1.52067e-31 (rank : 25)
Query Neighborhood Hits	107	Target Neighborhood Hits	84	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
NC score	0.804196 (rank : 17)	θ value	2.19584e-30 (rank : 26)
Query Neighborhood Hits	107	Target Neighborhood Hits	125	Shared Neighborhood Hits	41
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
NC score	0.804020 (rank : 18)	θ value	7.29293e-34 (rank : 22)
Query Neighborhood Hits	107	Target Neighborhood Hits	198	Shared Neighborhood Hits	43
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

HCN1_HUMAN
NC score	0.802843 (rank : 19)	θ value	5.96599e-36 (rank : 19)
Query Neighborhood Hits	107	Target Neighborhood Hits	120	Shared Neighborhood Hits	41
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
NC score	0.799298 (rank : 20)	θ value	5.96599e-36 (rank : 20)
Query Neighborhood Hits	107	Target Neighborhood Hits	172	Shared Neighborhood Hits	44
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN3_MOUSE
NC score	0.797947 (rank : 21)	θ value	3.06405e-32 (rank : 23)
Query Neighborhood Hits	107	Target Neighborhood Hits	112	Shared Neighborhood Hits	37
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN3_HUMAN
NC score	0.797655 (rank : 22)	θ value	8.91499e-32 (rank : 24)
Query Neighborhood Hits	107	Target Neighborhood Hits	99	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN2_MOUSE
NC score	0.786764 (rank : 23)	θ value	9.20422e-37 (rank : 15)
Query Neighborhood Hits	107	Target Neighborhood Hits	278	Shared Neighborhood Hits	43
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_HUMAN
NC score	0.783640 (rank : 24)	θ value	3.73686e-38 (rank : 14)
Query Neighborhood Hits	107	Target Neighborhood Hits	303	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
NC score	0.781018 (rank : 25)	θ value	4.568e-36 (rank : 17)
Query Neighborhood Hits	107	Target Neighborhood Hits	284	Shared Neighborhood Hits	39
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_HUMAN
NC score	0.778376 (rank : 26)	θ value	1.57e-36 (rank : 16)
Query Neighborhood Hits	107	Target Neighborhood Hits	369	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CNGB3_MOUSE
NC score	0.747367 (rank : 27)	θ value	4.29542e-18 (rank : 28)
Query Neighborhood Hits	107	Target Neighborhood Hits	74	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
NC score	0.733286 (rank : 28)	θ value	1.47631e-18 (rank : 27)
Query Neighborhood Hits	107	Target Neighborhood Hits	206	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB1_HUMAN
NC score	0.724889 (rank : 29)	θ value	2.35696e-16 (rank : 29)
Query Neighborhood Hits	107	Target Neighborhood Hits	222	Shared Neighborhood Hits	41
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNKH_HUMAN
NC score	0.256148 (rank : 30)	θ value	0.000786445 (rank : 30)
Query Neighborhood Hits	107	Target Neighborhood Hits	89	Shared Neighborhood Hits	50
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNKF_HUMAN
NC score	0.194678 (rank : 31)	θ value	0.0113563 (rank : 35)
Query Neighborhood Hits	107	Target Neighborhood Hits	87	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNK2_HUMAN
NC score	0.190917 (rank : 32)	θ value	0.0113563 (rank : 33)
Query Neighborhood Hits	107	Target Neighborhood Hits	86	Shared Neighborhood Hits	50
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
NC score	0.190278 (rank : 33)	θ value	0.0113563 (rank : 34)
Query Neighborhood Hits	107	Target Neighborhood Hits	88	Shared Neighborhood Hits	50
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_HUMAN
NC score	0.182007 (rank : 34)	θ value	0.0961366 (rank : 43)
Query Neighborhood Hits	107	Target Neighborhood Hits	88	Shared Neighborhood Hits	50
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK6_HUMAN
NC score	0.181656 (rank : 35)	θ value	0.0563607 (rank : 39)
Query Neighborhood Hits	107	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNKA_HUMAN
NC score	0.180640 (rank : 36)	θ value	0.0563607 (rank : 40)
Query Neighborhood Hits	107	Target Neighborhood Hits	111	Shared Neighborhood Hits	51
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNK3_MOUSE
NC score	0.179053 (rank : 37)	θ value	0.0431538 (rank : 37)
Query Neighborhood Hits	107	Target Neighborhood Hits	93	Shared Neighborhood Hits	50
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNKG_HUMAN
NC score	0.170927 (rank : 38)	θ value	0.0736092 (rank : 41)
Query Neighborhood Hits	107	Target Neighborhood Hits	90	Shared Neighborhood Hits	48
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNK4_HUMAN
NC score	0.168897 (rank : 39)	θ value	0.279714 (rank : 47)
Query Neighborhood Hits	107	Target Neighborhood Hits	109	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KAP0_HUMAN
NC score	0.168648 (rank : 40)	θ value	0.0961366 (rank : 42)
Query Neighborhood Hits	107	Target Neighborhood Hits	52	Shared Neighborhood Hits	33
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KCNK4_MOUSE
NC score	0.158648 (rank : 41)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	107	Target Neighborhood Hits	118	Shared Neighborhood Hits	46
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KAP0_MOUSE
NC score	0.157688 (rank : 42)	θ value	0.0563607 (rank : 38)
Query Neighborhood Hits	107	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KCNK9_MOUSE
NC score	0.152362 (rank : 43)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	107	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCNK9_HUMAN
NC score	0.152250 (rank : 44)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	107	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KAP1_HUMAN
NC score	0.145024 (rank : 45)	θ value	0.125558 (rank : 44)
Query Neighborhood Hits	107	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
NC score	0.142782 (rank : 46)	θ value	0.125558 (rank : 45)
Query Neighborhood Hits	107	Target Neighborhood Hits	49	Shared Neighborhood Hits	31
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KCNK5_HUMAN
NC score	0.130560 (rank : 47)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	107	Target Neighborhood Hits	102	Shared Neighborhood Hits	52
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KCNK1_HUMAN
NC score	0.130428 (rank : 48)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	107	Target Neighborhood Hits	68	Shared Neighborhood Hits	43
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNK1_MOUSE
NC score	0.125791 (rank : 49)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	107	Target Neighborhood Hits	70	Shared Neighborhood Hits	41
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KCNKD_MOUSE
NC score	0.105634 (rank : 50)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	107	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KAP3_MOUSE
NC score	0.101456 (rank : 51)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	107	Target Neighborhood Hits	43	Shared Neighborhood Hits	26
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP2_MOUSE
NC score	0.100639 (rank : 52)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	107	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_HUMAN
NC score	0.098571 (rank : 53)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	107	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_HUMAN
NC score	0.098228 (rank : 54)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	107	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KCNKD_HUMAN
NC score	0.084642 (rank : 55)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	107	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNKC_HUMAN
NC score	0.082680 (rank : 56)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	107	Target Neighborhood Hits	51	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

KCNQ3_MOUSE
NC score	0.076963 (rank : 57)	θ value	0.00869519 (rank : 32)
Query Neighborhood Hits	107	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNK7_MOUSE
NC score	0.075078 (rank : 58)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	107	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNQ3_HUMAN
NC score	0.074978 (rank : 59)	θ value	0.0113563 (rank : 36)
Query Neighborhood Hits	107	Target Neighborhood Hits	114	Shared Neighborhood Hits	44
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

CT152_MOUSE
NC score	0.071043 (rank : 60)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	107	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KCND1_MOUSE
NC score	0.068476 (rank : 61)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	107	Target Neighborhood Hits	165	Shared Neighborhood Hits	50
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCMA1_MOUSE
NC score	0.063537 (rank : 62)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	107	Target Neighborhood Hits	94	Shared Neighborhood Hits	40
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCMA1_HUMAN
NC score	0.063419 (rank : 63)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	107	Target Neighborhood Hits	96	Shared Neighborhood Hits	40
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCND1_HUMAN
NC score	0.062906 (rank : 64)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	107	Target Neighborhood Hits	160	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND2_HUMAN
NC score	0.060640 (rank : 65)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	107	Target Neighborhood Hits	154	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
NC score	0.060629 (rank : 66)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	107	Target Neighborhood Hits	156	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCNK7_HUMAN
NC score	0.058142 (rank : 67)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	107	Target Neighborhood Hits	42	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCND3_MOUSE
NC score	0.057593 (rank : 68)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	107	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.057564 (rank : 69)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	107	Target Neighborhood Hits	162	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNQ2_HUMAN
NC score	0.057541 (rank : 70)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	107	Target Neighborhood Hits	114	Shared Neighborhood Hits	44
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
NC score	0.056516 (rank : 71)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	107	Target Neighborhood Hits	163	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ4_HUMAN
NC score	0.051006 (rank : 72)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	107	Target Neighborhood Hits	136	Shared Neighborhood Hits	39
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

RPGF4_MOUSE
NC score	0.048738 (rank : 73)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	107	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

KGP1B_HUMAN
NC score	0.045699 (rank : 74)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	107	Target Neighborhood Hits	921	Shared Neighborhood Hits	42
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
NC score	0.045671 (rank : 75)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	107	Target Neighborhood Hits	901	Shared Neighborhood Hits	42
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_MOUSE
NC score	0.045287 (rank : 76)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	107	Target Neighborhood Hits	922	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

RPGF4_HUMAN
NC score	0.044093 (rank : 77)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	107	Target Neighborhood Hits	88	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

KCNN4_HUMAN
NC score	0.038137 (rank : 78)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	107	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

KCNN4_MOUSE
NC score	0.035103 (rank : 79)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	107	Target Neighborhood Hits	85	Shared Neighborhood Hits	41
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

KGP2_HUMAN
NC score	0.033184 (rank : 80)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	107	Target Neighborhood Hits	1023	Shared Neighborhood Hits	34
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KCNF1_HUMAN
NC score	0.027632 (rank : 81)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	107	Target Neighborhood Hits	109	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

CJ049_HUMAN
NC score	0.026129 (rank : 82)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	107	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WVF2	Gene names	C10orf49
Domain Architecture	No domain graphic available
Description	Protein C10orf49 precursor.

KCNA2_MOUSE
NC score	0.025563 (rank : 83)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	107	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA2_HUMAN
NC score	0.024586 (rank : 84)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	107	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

SRRM2_MOUSE
NC score	0.020524 (rank : 85)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	107	Target Neighborhood Hits	1470	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TM119_HUMAN
NC score	0.013006 (rank : 86)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	107	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q4V9L6, Q6UXE5, Q8N2F5	Gene names	TMEM119
Domain Architecture	No domain graphic available
Description	Transmembrane protein 119 precursor.

CCNF_MOUSE
NC score	0.012273 (rank : 87)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	107	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P51944, Q60797, Q60799	Gene names	Ccnf
Domain Architecture
Description	G2/mitotic-specific cyclin-F.

LEO1_HUMAN
NC score	0.012112 (rank : 88)	θ value	1.38821 (rank : 64)
Query Neighborhood Hits	107	Target Neighborhood Hits	958	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

GOGA1_MOUSE
NC score	0.011603 (rank : 89)	θ value	0.279714 (rank : 46)
Query Neighborhood Hits	107	Target Neighborhood Hits	994	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

MACOI_HUMAN
NC score	0.010155 (rank : 90)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	107	Target Neighborhood Hits	650	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

CEND1_HUMAN
NC score	0.009955 (rank : 91)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	107	Target Neighborhood Hits	284	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CAYP2_HUMAN
NC score	0.009864 (rank : 92)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	107	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXY5, Q6PH84, Q8N242, Q8NAY5	Gene names	CAPS2
Domain Architecture
Description	Calcyphosin-2 (Calcyphosine-2).

CP135_MOUSE
NC score	0.009249 (rank : 93)	θ value	0.00228821 (rank : 31)
Query Neighborhood Hits	107	Target Neighborhood Hits	1278	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MACOI_MOUSE
NC score	0.009084 (rank : 94)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	107	Target Neighborhood Hits	620	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

SIA7A_HUMAN
NC score	0.008258 (rank : 95)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	107	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

URFB1_HUMAN
NC score	0.007593 (rank : 96)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	107	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q6BDS2, Q9NXE0	Gene names	UHRF1BP1, C6orf107
Domain Architecture	No domain graphic available
Description	UHRF1-binding protein 1 (Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1) (ICBP90-binding protein 1).

RND1_HUMAN
NC score	0.007327 (rank : 97)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	107	Target Neighborhood Hits	230	Shared Neighborhood Hits	4
SwissProt Accessions	Q92730	Gene names	RND1, RHO6
Domain Architecture
Description	Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1).

SLIK1_HUMAN
NC score	0.006509 (rank : 98)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	107	Target Neighborhood Hits	297	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PX8, Q5U5I6, Q96SF9	Gene names	SLITRK1, KIAA1910, LRRC12
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor (Leucine-rich repeat-containing protein 12).

SLIK1_MOUSE
NC score	0.006439 (rank : 99)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	107	Target Neighborhood Hits	333	Shared Neighborhood Hits	5
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

RND1_MOUSE
NC score	0.006383 (rank : 100)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	107	Target Neighborhood Hits	228	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BLR7, Q3TSQ9, Q80ZR7, Q8BYF2	Gene names	Rnd1, Rho6
Domain Architecture	No domain graphic available
Description	Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1).

ABTAP_MOUSE
NC score	0.005894 (rank : 101)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	107	Target Neighborhood Hits	381	Shared Neighborhood Hits	6
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

STON2_HUMAN
NC score	0.005416 (rank : 102)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	107	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

DTNB_MOUSE
NC score	0.005333 (rank : 103)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	107	Target Neighborhood Hits	263	Shared Neighborhood Hits	4
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

LRCH2_HUMAN
NC score	0.005122 (rank : 104)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	107	Target Neighborhood Hits	315	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

CLCA_MOUSE
NC score	0.005003 (rank : 105)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	107	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	O08585	Gene names	Clta
Domain Architecture
Description	Clathrin light chain A (Lca).

LIPB1_HUMAN
NC score	0.004665 (rank : 106)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	107	Target Neighborhood Hits	640	Shared Neighborhood Hits	7
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

S14L4_HUMAN
NC score	0.004431 (rank : 107)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	107	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UDX3	Gene names	SEC14L4, TAP3
Domain Architecture
Description	SEC14-like protein 4 (Tocopherol-associated protein 3).

RFC1_MOUSE
NC score	0.003613 (rank : 108)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	107	Target Neighborhood Hits	290	Shared Neighborhood Hits	2
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

ABCAD_MOUSE
NC score	0.002911 (rank : 109)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	107	Target Neighborhood Hits	150	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

LIPB1_MOUSE
NC score	0.002783 (rank : 110)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	107	Target Neighborhood Hits	727	Shared Neighborhood Hits	10
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

TPR_HUMAN
NC score	0.001970 (rank : 111)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	107	Target Neighborhood Hits	1921	Shared Neighborhood Hits	23
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TEX14_MOUSE
NC score	0.001394 (rank : 112)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	107	Target Neighborhood Hits	1333	Shared Neighborhood Hits	15
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

HIP1_HUMAN
NC score	0.001122 (rank : 113)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	107	Target Neighborhood Hits	1016	Shared Neighborhood Hits	10
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

CD2L7_HUMAN
NC score	-0.004053 (rank : 114)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	107	Target Neighborhood Hits	1275	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).