Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : KCNH3_HUMAN

For an explanation of this page, click here

KCNH3_HUMAN
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KCNH3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	148	Target Neighborhood Hits	148	Shared Neighborhood Hits	148
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
θ value	0 (rank : 2)	NC score	0.994671 (rank : 2)
Query Neighborhood Hits	148	Target Neighborhood Hits	133	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH4_HUMAN
θ value	0 (rank : 3)	NC score	0.980859 (rank : 4)
Query Neighborhood Hits	148	Target Neighborhood Hits	177	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH8_HUMAN
θ value	0 (rank : 4)	NC score	0.984717 (rank : 3)
Query Neighborhood Hits	148	Target Neighborhood Hits	104	Shared Neighborhood Hits	54
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH6_HUMAN
θ value	2.77624e-142 (rank : 5)	NC score	0.960920 (rank : 9)
Query Neighborhood Hits	148	Target Neighborhood Hits	222	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH1_MOUSE
θ value	2.35568e-133 (rank : 6)	NC score	0.961927 (rank : 5)
Query Neighborhood Hits	148	Target Neighborhood Hits	94	Shared Neighborhood Hits	50
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH5_MOUSE
θ value	2.35568e-133 (rank : 7)	NC score	0.961581 (rank : 8)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	49
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
θ value	4.01817e-133 (rank : 8)	NC score	0.961603 (rank : 7)
Query Neighborhood Hits	148	Target Neighborhood Hits	99	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH1_HUMAN
θ value	5.24793e-133 (rank : 9)	NC score	0.961732 (rank : 6)
Query Neighborhood Hits	148	Target Neighborhood Hits	98	Shared Neighborhood Hits	50
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH2_MOUSE
θ value	1.02895e-112 (rank : 10)	NC score	0.951699 (rank : 11)
Query Neighborhood Hits	148	Target Neighborhood Hits	165	Shared Neighborhood Hits	62
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH2_HUMAN
θ value	2.9938e-112 (rank : 11)	NC score	0.951879 (rank : 10)
Query Neighborhood Hits	148	Target Neighborhood Hits	158	Shared Neighborhood Hits	62
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH7_MOUSE
θ value	2.89973e-107 (rank : 12)	NC score	0.950001 (rank : 12)
Query Neighborhood Hits	148	Target Neighborhood Hits	98	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH7_HUMAN
θ value	3.54468e-105 (rank : 13)	NC score	0.948978 (rank : 13)
Query Neighborhood Hits	148	Target Neighborhood Hits	107	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

CNGA3_HUMAN
θ value	8.91499e-32 (rank : 14)	NC score	0.793382 (rank : 18)
Query Neighborhood Hits	148	Target Neighborhood Hits	125	Shared Neighborhood Hits	33
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
θ value	1.52067e-31 (rank : 15)	NC score	0.793801 (rank : 17)
Query Neighborhood Hits	148	Target Neighborhood Hits	198	Shared Neighborhood Hits	33
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
θ value	4.42448e-31 (rank : 16)	NC score	0.797070 (rank : 16)
Query Neighborhood Hits	148	Target Neighborhood Hits	84	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA2_MOUSE
θ value	1.28732e-30 (rank : 17)	NC score	0.806607 (rank : 14)
Query Neighborhood Hits	148	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA1_HUMAN
θ value	1.6813e-30 (rank : 18)	NC score	0.797659 (rank : 15)
Query Neighborhood Hits	148	Target Neighborhood Hits	149	Shared Neighborhood Hits	32
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

HCN4_HUMAN
θ value	1.4233e-29 (rank : 19)	NC score	0.765714 (rank : 24)
Query Neighborhood Hits	148	Target Neighborhood Hits	303	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN1_HUMAN
θ value	2.42779e-29 (rank : 20)	NC score	0.781330 (rank : 19)
Query Neighborhood Hits	148	Target Neighborhood Hits	120	Shared Neighborhood Hits	37
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
θ value	2.42779e-29 (rank : 21)	NC score	0.777668 (rank : 20)
Query Neighborhood Hits	148	Target Neighborhood Hits	172	Shared Neighborhood Hits	37
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN2_MOUSE
θ value	5.40856e-29 (rank : 22)	NC score	0.767830 (rank : 23)
Query Neighborhood Hits	148	Target Neighborhood Hits	278	Shared Neighborhood Hits	58
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_MOUSE
θ value	5.40856e-29 (rank : 23)	NC score	0.764949 (rank : 25)
Query Neighborhood Hits	148	Target Neighborhood Hits	284	Shared Neighborhood Hits	64
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_HUMAN
θ value	7.06379e-29 (rank : 24)	NC score	0.761466 (rank : 26)
Query Neighborhood Hits	148	Target Neighborhood Hits	369	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN3_MOUSE
θ value	6.61148e-27 (rank : 25)	NC score	0.775874 (rank : 22)
Query Neighborhood Hits	148	Target Neighborhood Hits	112	Shared Neighborhood Hits	37
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN3_HUMAN
θ value	1.12775e-26 (rank : 26)	NC score	0.776507 (rank : 21)
Query Neighborhood Hits	148	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

CNGB1_HUMAN
θ value	3.63628e-17 (rank : 27)	NC score	0.715553 (rank : 29)
Query Neighborhood Hits	148	Target Neighborhood Hits	222	Shared Neighborhood Hits	44
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_HUMAN
θ value	9.90251e-15 (rank : 28)	NC score	0.717019 (rank : 28)
Query Neighborhood Hits	148	Target Neighborhood Hits	206	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_MOUSE
θ value	4.91457e-14 (rank : 29)	NC score	0.727910 (rank : 27)
Query Neighborhood Hits	148	Target Neighborhood Hits	74	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

KCNKH_HUMAN
θ value	0.00175202 (rank : 30)	NC score	0.249220 (rank : 30)
Query Neighborhood Hits	148	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNK3_MOUSE
θ value	0.00869519 (rank : 31)	NC score	0.178806 (rank : 35)
Query Neighborhood Hits	148	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK3_HUMAN
θ value	0.0113563 (rank : 32)	NC score	0.182208 (rank : 32)
Query Neighborhood Hits	148	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNKF_HUMAN
θ value	0.0193708 (rank : 33)	NC score	0.189068 (rank : 31)
Query Neighborhood Hits	148	Target Neighborhood Hits	87	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNKA_HUMAN
θ value	0.0431538 (rank : 34)	NC score	0.174029 (rank : 36)
Query Neighborhood Hits	148	Target Neighborhood Hits	111	Shared Neighborhood Hits	34
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

CCG8_MOUSE
θ value	0.0563607 (rank : 35)	NC score	0.019364 (rank : 98)
Query Neighborhood Hits	148	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHW2	Gene names	Cacng8
Domain Architecture
Description	Voltage-dependent calcium channel gamma-8 subunit (Neuronal voltage- gated calcium channel gamma-8 subunit).

KCNK2_HUMAN
θ value	0.0563607 (rank : 36)	NC score	0.182061 (rank : 33)
Query Neighborhood Hits	148	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	0.0563607 (rank : 37)	NC score	0.181386 (rank : 34)
Query Neighborhood Hits	148	Target Neighborhood Hits	88	Shared Neighborhood Hits	32
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

MAST2_HUMAN
θ value	0.0736092 (rank : 38)	NC score	0.004396 (rank : 146)
Query Neighborhood Hits	148	Target Neighborhood Hits	1189	Shared Neighborhood Hits	26
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAGE1_HUMAN
θ value	0.0961366 (rank : 39)	NC score	0.034663 (rank : 71)
Query Neighborhood Hits	148	Target Neighborhood Hits	1389	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

BICD1_HUMAN
θ value	0.125558 (rank : 40)	NC score	0.015975 (rank : 113)
Query Neighborhood Hits	148	Target Neighborhood Hits	844	Shared Neighborhood Hits	10
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

TARA_MOUSE
θ value	0.163984 (rank : 41)	NC score	0.017361 (rank : 105)
Query Neighborhood Hits	148	Target Neighborhood Hits	1133	Shared Neighborhood Hits	29
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

KCNK4_HUMAN
θ value	0.21417 (rank : 42)	NC score	0.166641 (rank : 38)
Query Neighborhood Hits	148	Target Neighborhood Hits	109	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KGP1A_HUMAN
θ value	0.21417 (rank : 43)	NC score	0.042800 (rank : 63)
Query Neighborhood Hits	148	Target Neighborhood Hits	901	Shared Neighborhood Hits	40
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	0.21417 (rank : 44)	NC score	0.042853 (rank : 62)
Query Neighborhood Hits	148	Target Neighborhood Hits	921	Shared Neighborhood Hits	40
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

BSN_MOUSE
θ value	0.279714 (rank : 45)	NC score	0.034905 (rank : 70)
Query Neighborhood Hits	148	Target Neighborhood Hits	2057	Shared Neighborhood Hits	65
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

KCNK9_HUMAN
θ value	0.279714 (rank : 46)	NC score	0.153035 (rank : 41)
Query Neighborhood Hits	148	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK9_MOUSE
θ value	0.279714 (rank : 47)	NC score	0.153184 (rank : 40)
Query Neighborhood Hits	148	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

MUC1_HUMAN
θ value	0.279714 (rank : 48)	NC score	0.020424 (rank : 93)
Query Neighborhood Hits	148	Target Neighborhood Hits	975	Shared Neighborhood Hits	37
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CHD4_HUMAN
θ value	0.365318 (rank : 49)	NC score	0.016928 (rank : 110)
Query Neighborhood Hits	148	Target Neighborhood Hits	365	Shared Neighborhood Hits	8
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	0.365318 (rank : 50)	NC score	0.017805 (rank : 104)
Query Neighborhood Hits	148	Target Neighborhood Hits	408	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	0.365318 (rank : 51)	NC score	0.018233 (rank : 103)
Query Neighborhood Hits	148	Target Neighborhood Hits	349	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

NRX2A_HUMAN
θ value	0.365318 (rank : 52)	NC score	0.027013 (rank : 80)
Query Neighborhood Hits	148	Target Neighborhood Hits	614	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	0.365318 (rank : 53)	NC score	0.040390 (rank : 65)
Query Neighborhood Hits	148	Target Neighborhood Hits	481	Shared Neighborhood Hits	19
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

EPN3_HUMAN
θ value	0.47712 (rank : 54)	NC score	0.035038 (rank : 69)
Query Neighborhood Hits	148	Target Neighborhood Hits	197	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

KCNK6_HUMAN
θ value	0.47712 (rank : 55)	NC score	0.171806 (rank : 37)
Query Neighborhood Hits	148	Target Neighborhood Hits	79	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KGP1B_MOUSE
θ value	0.47712 (rank : 56)	NC score	0.042375 (rank : 64)
Query Neighborhood Hits	148	Target Neighborhood Hits	922	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

TS13_MOUSE
θ value	0.47712 (rank : 57)	NC score	0.032954 (rank : 74)
Query Neighborhood Hits	148	Target Neighborhood Hits	191	Shared Neighborhood Hits	6
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

BICD1_MOUSE
θ value	0.62314 (rank : 58)	NC score	0.012589 (rank : 122)
Query Neighborhood Hits	148	Target Neighborhood Hits	837	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

JPH2_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.032166 (rank : 75)
Query Neighborhood Hits	148	Target Neighborhood Hits	639	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

KCNK5_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.125483 (rank : 45)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

RTP3_MOUSE
θ value	0.62314 (rank : 61)	NC score	0.021772 (rank : 88)
Query Neighborhood Hits	148	Target Neighborhood Hits	374	Shared Neighborhood Hits	20
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SEM6B_HUMAN
θ value	0.62314 (rank : 62)	NC score	0.008367 (rank : 135)
Query Neighborhood Hits	148	Target Neighborhood Hits	187	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

PRRT3_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.036709 (rank : 66)
Query Neighborhood Hits	148	Target Neighborhood Hits	998	Shared Neighborhood Hits	46
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SENP3_MOUSE
θ value	0.813845 (rank : 64)	NC score	0.014601 (rank : 118)
Query Neighborhood Hits	148	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

KCNK4_MOUSE
θ value	1.06291 (rank : 65)	NC score	0.152361 (rank : 42)
Query Neighborhood Hits	148	Target Neighborhood Hits	118	Shared Neighborhood Hits	35
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCNKG_HUMAN
θ value	1.06291 (rank : 66)	NC score	0.158686 (rank : 39)
Query Neighborhood Hits	148	Target Neighborhood Hits	90	Shared Neighborhood Hits	30
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

SON_HUMAN
θ value	1.06291 (rank : 67)	NC score	0.017306 (rank : 106)
Query Neighborhood Hits	148	Target Neighborhood Hits	1568	Shared Neighborhood Hits	41
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CMTA2_MOUSE
θ value	1.38821 (rank : 68)	NC score	0.016866 (rank : 111)
Query Neighborhood Hits	148	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

BIN1_MOUSE
θ value	1.81305 (rank : 69)	NC score	0.020321 (rank : 95)
Query Neighborhood Hits	148	Target Neighborhood Hits	283	Shared Neighborhood Hits	19
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

CEP68_HUMAN
θ value	1.81305 (rank : 70)	NC score	0.025124 (rank : 82)
Query Neighborhood Hits	148	Target Neighborhood Hits	128	Shared Neighborhood Hits	9
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

DAB2_HUMAN
θ value	1.81305 (rank : 71)	NC score	0.018446 (rank : 101)
Query Neighborhood Hits	148	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

KKCC1_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.000567 (rank : 153)
Query Neighborhood Hits	148	Target Neighborhood Hits	858	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N5S9, Q9BQH3	Gene names	CAMKK1, CAMKKA
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

LCOR_MOUSE
θ value	1.81305 (rank : 73)	NC score	0.021764 (rank : 89)
Query Neighborhood Hits	148	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZPI3, Q3U302, Q5CZW7, Q80VA8, Q8BGT2, Q8C9Q0	Gene names	Lcor, Kiaa1795, Mlr2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

LIMD1_MOUSE
θ value	1.81305 (rank : 74)	NC score	0.010196 (rank : 130)
Query Neighborhood Hits	148	Target Neighborhood Hits	291	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

PHLB1_MOUSE
θ value	1.81305 (rank : 75)	NC score	0.023954 (rank : 84)
Query Neighborhood Hits	148	Target Neighborhood Hits	678	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SAPS1_HUMAN
θ value	1.81305 (rank : 76)	NC score	0.036260 (rank : 67)
Query Neighborhood Hits	148	Target Neighborhood Hits	704	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

BIN1_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.023220 (rank : 86)
Query Neighborhood Hits	148	Target Neighborhood Hits	335	Shared Neighborhood Hits	17
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

CHD3_HUMAN
θ value	2.36792 (rank : 78)	NC score	0.015473 (rank : 116)
Query Neighborhood Hits	148	Target Neighborhood Hits	397	Shared Neighborhood Hits	12
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CXXC6_HUMAN
θ value	2.36792 (rank : 79)	NC score	0.023436 (rank : 85)
Query Neighborhood Hits	148	Target Neighborhood Hits	180	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

FOXN1_MOUSE
θ value	2.36792 (rank : 80)	NC score	0.013680 (rank : 121)
Query Neighborhood Hits	148	Target Neighborhood Hits	300	Shared Neighborhood Hits	13
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

HAIR_HUMAN
θ value	2.36792 (rank : 81)	NC score	0.026850 (rank : 81)
Query Neighborhood Hits	148	Target Neighborhood Hits	172	Shared Neighborhood Hits	10
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

KCNN4_HUMAN
θ value	2.36792 (rank : 82)	NC score	0.036259 (rank : 68)
Query Neighborhood Hits	148	Target Neighborhood Hits	90	Shared Neighborhood Hits	27
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

PDZD6_HUMAN
θ value	2.36792 (rank : 83)	NC score	0.017252 (rank : 108)
Query Neighborhood Hits	148	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

ZN687_HUMAN
θ value	2.36792 (rank : 84)	NC score	0.007406 (rank : 137)
Query Neighborhood Hits	148	Target Neighborhood Hits	1244	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

EGR4_HUMAN
θ value	3.0926 (rank : 85)	NC score	-0.002502 (rank : 158)
Query Neighborhood Hits	148	Target Neighborhood Hits	939	Shared Neighborhood Hits	17
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

FOXN1_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.017278 (rank : 107)
Query Neighborhood Hits	148	Target Neighborhood Hits	377	Shared Neighborhood Hits	15
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

GA2L2_MOUSE
θ value	3.0926 (rank : 87)	NC score	0.012166 (rank : 124)
Query Neighborhood Hits	148	Target Neighborhood Hits	395	Shared Neighborhood Hits	17
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

INVS_MOUSE
θ value	3.0926 (rank : 88)	NC score	0.006408 (rank : 142)
Query Neighborhood Hits	148	Target Neighborhood Hits	609	Shared Neighborhood Hits	24
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

KCNK1_HUMAN
θ value	3.0926 (rank : 89)	NC score	0.126119 (rank : 43)
Query Neighborhood Hits	148	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNN4_MOUSE
θ value	3.0926 (rank : 90)	NC score	0.033355 (rank : 73)
Query Neighborhood Hits	148	Target Neighborhood Hits	85	Shared Neighborhood Hits	26
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

LCOR_HUMAN
θ value	3.0926 (rank : 91)	NC score	0.019948 (rank : 97)
Query Neighborhood Hits	148	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JN0, Q5VW16, Q7Z723, Q86T32, Q86T33, Q8N3L6	Gene names	LCOR, KIAA1795, MLR2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

MINP1_HUMAN
θ value	3.0926 (rank : 92)	NC score	0.032146 (rank : 76)
Query Neighborhood Hits	148	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNW1, O95172, O95286, Q59EJ2, Q9UGA3	Gene names	MINPP1, MIPP
Domain Architecture	No domain graphic available
Description	Multiple inositol polyphosphate phosphatase 1 precursor (EC 3.1.3.62) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase).

NFH_MOUSE
θ value	3.0926 (rank : 93)	NC score	0.018638 (rank : 100)
Query Neighborhood Hits	148	Target Neighborhood Hits	2247	Shared Neighborhood Hits	62
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PK2L1_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.010698 (rank : 128)
Query Neighborhood Hits	148	Target Neighborhood Hits	132	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PSL1_HUMAN
θ value	3.0926 (rank : 95)	NC score	0.043056 (rank : 61)
Query Neighborhood Hits	148	Target Neighborhood Hits	650	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

PSL1_MOUSE
θ value	3.0926 (rank : 96)	NC score	0.018282 (rank : 102)
Query Neighborhood Hits	148	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q3TD49, Q3TLQ8, Q3UG60, Q80VZ6	Gene names	Sppl2b
Domain Architecture	No domain graphic available
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b).

RGS3_MOUSE
θ value	3.0926 (rank : 97)	NC score	0.030584 (rank : 78)
Query Neighborhood Hits	148	Target Neighborhood Hits	1621	Shared Neighborhood Hits	55
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SC24C_HUMAN
θ value	3.0926 (rank : 98)	NC score	0.031556 (rank : 77)
Query Neighborhood Hits	148	Target Neighborhood Hits	662	Shared Neighborhood Hits	35
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

UBP42_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.006517 (rank : 141)
Query Neighborhood Hits	148	Target Neighborhood Hits	445	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

XKR7_MOUSE
θ value	3.0926 (rank : 100)	NC score	0.017194 (rank : 109)
Query Neighborhood Hits	148	Target Neighborhood Hits	146	Shared Neighborhood Hits	8
SwissProt Accessions	Q5GH64	Gene names	Xkr7, Xrg7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

CK056_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.011023 (rank : 126)
Query Neighborhood Hits	148	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N612, Q9C0A4, Q9H0N3, Q9H624	Gene names	C11orf56, KIAA1759
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf56.

EPAS1_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.004394 (rank : 147)
Query Neighborhood Hits	148	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

JPH1_MOUSE
θ value	4.03905 (rank : 103)	NC score	0.012519 (rank : 123)
Query Neighborhood Hits	148	Target Neighborhood Hits	120	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ET80, Q9EQZ3	Gene names	Jph1, Jp1
Domain Architecture
Description	Junctophilin-1 (Junctophilin type 1) (JP-1).

KCNK1_MOUSE
θ value	4.03905 (rank : 104)	NC score	0.122328 (rank : 46)
Query Neighborhood Hits	148	Target Neighborhood Hits	70	Shared Neighborhood Hits	37
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

MAST4_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.007916 (rank : 136)
Query Neighborhood Hits	148	Target Neighborhood Hits	1804	Shared Neighborhood Hits	55
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NBEA_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.008818 (rank : 134)
Query Neighborhood Hits	148	Target Neighborhood Hits	186	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

NBEA_MOUSE
θ value	4.03905 (rank : 107)	NC score	0.008931 (rank : 133)
Query Neighborhood Hits	148	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

OBSCN_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.001724 (rank : 151)
Query Neighborhood Hits	148	Target Neighborhood Hits	1931	Shared Neighborhood Hits	42
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

RP1L1_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.011729 (rank : 125)
Query Neighborhood Hits	148	Target Neighborhood Hits	1072	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SUSD4_MOUSE
θ value	4.03905 (rank : 110)	NC score	0.006143 (rank : 143)
Query Neighborhood Hits	148	Target Neighborhood Hits	122	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

APXL_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.010323 (rank : 129)
Query Neighborhood Hits	148	Target Neighborhood Hits	553	Shared Neighborhood Hits	21
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CAMKV_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.003255 (rank : 150)
Query Neighborhood Hits	148	Target Neighborhood Hits	1084	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CI079_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.020210 (rank : 96)
Query Neighborhood Hits	148	Target Neighborhood Hits	288	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CJ108_HUMAN
θ value	5.27518 (rank : 114)	NC score	0.016114 (rank : 112)
Query Neighborhood Hits	148	Target Neighborhood Hits	165	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

DUS2_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.005672 (rank : 144)
Query Neighborhood Hits	148	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

EPN2_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.014473 (rank : 119)
Query Neighborhood Hits	148	Target Neighborhood Hits	111	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CHU3, O70447, Q8BZ85	Gene names	Epn2
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2).

KCND1_MOUSE
θ value	5.27518 (rank : 117)	NC score	0.046992 (rank : 60)
Query Neighborhood Hits	148	Target Neighborhood Hits	165	Shared Neighborhood Hits	35
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KSR1_MOUSE
θ value	5.27518 (rank : 118)	NC score	-0.000022 (rank : 154)
Query Neighborhood Hits	148	Target Neighborhood Hits	870	Shared Neighborhood Hits	14
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

STK10_HUMAN
θ value	5.27518 (rank : 119)	NC score	-0.000650 (rank : 155)
Query Neighborhood Hits	148	Target Neighborhood Hits	1921	Shared Neighborhood Hits	26
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ZN703_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.014751 (rank : 117)
Query Neighborhood Hits	148	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H7S9, Q5XG76	Gene names	ZNF703
Domain Architecture	No domain graphic available
Description	Zinc finger protein 703.

CAC1B_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.007058 (rank : 139)
Query Neighborhood Hits	148	Target Neighborhood Hits	351	Shared Neighborhood Hits	21
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

KCNN2_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.021593 (rank : 90)
Query Neighborhood Hits	148	Target Neighborhood Hits	117	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
θ value	6.88961 (rank : 123)	NC score	0.021570 (rank : 91)
Query Neighborhood Hits	148	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

M3K10_HUMAN
θ value	6.88961 (rank : 124)	NC score	-0.000873 (rank : 156)
Query Neighborhood Hits	148	Target Neighborhood Hits	1071	Shared Neighborhood Hits	22
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

MAP1B_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.010160 (rank : 131)
Query Neighborhood Hits	148	Target Neighborhood Hits	977	Shared Neighborhood Hits	23
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MILK1_MOUSE
θ value	6.88961 (rank : 126)	NC score	0.015517 (rank : 115)
Query Neighborhood Hits	148	Target Neighborhood Hits	788	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NACAM_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.034308 (rank : 72)
Query Neighborhood Hits	148	Target Neighborhood Hits	1866	Shared Neighborhood Hits	69
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCOA6_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.028458 (rank : 79)
Query Neighborhood Hits	148	Target Neighborhood Hits	1202	Shared Neighborhood Hits	47
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	6.88961 (rank : 129)	NC score	0.018868 (rank : 99)
Query Neighborhood Hits	148	Target Neighborhood Hits	1076	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

ZN227_HUMAN
θ value	6.88961 (rank : 130)	NC score	-0.003956 (rank : 161)
Query Neighborhood Hits	148	Target Neighborhood Hits	781	Shared Neighborhood Hits	7
SwissProt Accessions	Q86WZ6	Gene names	ZNF227
Domain Architecture	No domain graphic available
Description	Zinc finger protein 227.

CKLF_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.022903 (rank : 87)
Query Neighborhood Hits	148	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBR5, Q9UHM7, Q9UHN8, Q9UI41	Gene names	CKLF
Domain Architecture
Description	Chemokine-like factor (C32).

DGKG_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.001362 (rank : 152)
Query Neighborhood Hits	148	Target Neighborhood Hits	188	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

EMID1_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.005194 (rank : 145)
Query Neighborhood Hits	148	Target Neighborhood Hits	230	Shared Neighborhood Hits	17
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

EPN3_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.020754 (rank : 92)
Query Neighborhood Hits	148	Target Neighborhood Hits	312	Shared Neighborhood Hits	20
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

FA47B_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.024748 (rank : 83)
Query Neighborhood Hits	148	Target Neighborhood Hits	431	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

HD_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.009071 (rank : 132)
Query Neighborhood Hits	148	Target Neighborhood Hits	165	Shared Neighborhood Hits	10
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

IRS2_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.015859 (rank : 114)
Query Neighborhood Hits	148	Target Neighborhood Hits	248	Shared Neighborhood Hits	27
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

JPH2_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.013811 (rank : 120)
Query Neighborhood Hits	148	Target Neighborhood Hits	279	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

K0179_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.010943 (rank : 127)
Query Neighborhood Hits	148	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q14684, Q8TBZ4	Gene names	KIAA0179
Domain Architecture
Description	Protein KIAA0179.

MTR1L_HUMAN
θ value	8.99809 (rank : 140)	NC score	-0.002633 (rank : 159)
Query Neighborhood Hits	148	Target Neighborhood Hits	1180	Shared Neighborhood Hits	12
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

PANK1_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.003904 (rank : 148)
Query Neighborhood Hits	148	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4K6, Q9D3K1, Q9QXM8	Gene names	Pank1, Pank
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (mPank1) (mPank).

PLXB1_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.006715 (rank : 140)
Query Neighborhood Hits	148	Target Neighborhood Hits	259	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

PTC2_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.003762 (rank : 149)
Query Neighborhood Hits	148	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

TAU_MOUSE
θ value	8.99809 (rank : 144)	NC score	0.020381 (rank : 94)
Query Neighborhood Hits	148	Target Neighborhood Hits	502	Shared Neighborhood Hits	29
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

VASN_HUMAN
θ value	8.99809 (rank : 145)	NC score	-0.001514 (rank : 157)
Query Neighborhood Hits	148	Target Neighborhood Hits	449	Shared Neighborhood Hits	7
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

WD21C_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.007335 (rank : 138)
Query Neighborhood Hits	148	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NA75	Gene names	WDR21C
Domain Architecture	No domain graphic available
Description	WD repeat protein 21C.

ZF276_HUMAN
θ value	8.99809 (rank : 147)	NC score	-0.002805 (rank : 160)
Query Neighborhood Hits	148	Target Neighborhood Hits	768	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N554	Gene names	ZFP276
Domain Architecture	No domain graphic available
Description	Zinc finger protein 276 homolog (Zfp-276).

ZN169_HUMAN
θ value	8.99809 (rank : 148)	NC score	-0.004091 (rank : 162)
Query Neighborhood Hits	148	Target Neighborhood Hits	764	Shared Neighborhood Hits	7
SwissProt Accessions	Q14929, Q6PI28	Gene names	ZNF169
Domain Architecture	No domain graphic available
Description	Zinc finger protein 169.

CT152_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.059874 (rank : 58)
Query Neighborhood Hits	148	Target Neighborhood Hits	38	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KAP0_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.126066 (rank : 44)
Query Neighborhood Hits	148	Target Neighborhood Hits	52	Shared Neighborhood Hits	26
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP0_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.115004 (rank : 47)
Query Neighborhood Hits	148	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.104206 (rank : 48)
Query Neighborhood Hits	148	Target Neighborhood Hits	58	Shared Neighborhood Hits	24
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.101834 (rank : 49)
Query Neighborhood Hits	148	Target Neighborhood Hits	49	Shared Neighborhood Hits	24
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP2_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.073723 (rank : 54)
Query Neighborhood Hits	148	Target Neighborhood Hits	48	Shared Neighborhood Hits	16
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.075813 (rank : 52)
Query Neighborhood Hits	148	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.073902 (rank : 53)
Query Neighborhood Hits	148	Target Neighborhood Hits	40	Shared Neighborhood Hits	19
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.077118 (rank : 51)
Query Neighborhood Hits	148	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KCNK7_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.052615 (rank : 59)
Query Neighborhood Hits	148	Target Neighborhood Hits	42	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCNK7_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.069353 (rank : 56)
Query Neighborhood Hits	148	Target Neighborhood Hits	53	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNKC_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.066618 (rank : 57)
Query Neighborhood Hits	148	Target Neighborhood Hits	51	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

KCNKD_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.070904 (rank : 55)
Query Neighborhood Hits	148	Target Neighborhood Hits	58	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNKD_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.088200 (rank : 50)
Query Neighborhood Hits	148	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

Hits sorted by NC score

KCNH3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	148	Target Neighborhood Hits	148	Shared Neighborhood Hits	148
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
NC score	0.994671 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	148	Target Neighborhood Hits	133	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH8_HUMAN
NC score	0.984717 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	148	Target Neighborhood Hits	104	Shared Neighborhood Hits	54
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH4_HUMAN
NC score	0.980859 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	148	Target Neighborhood Hits	177	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH1_MOUSE
NC score	0.961927 (rank : 5)	θ value	2.35568e-133 (rank : 6)
Query Neighborhood Hits	148	Target Neighborhood Hits	94	Shared Neighborhood Hits	50
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.961732 (rank : 6)	θ value	5.24793e-133 (rank : 9)
Query Neighborhood Hits	148	Target Neighborhood Hits	98	Shared Neighborhood Hits	50
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH5_HUMAN
NC score	0.961603 (rank : 7)	θ value	4.01817e-133 (rank : 8)
Query Neighborhood Hits	148	Target Neighborhood Hits	99	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH5_MOUSE
NC score	0.961581 (rank : 8)	θ value	2.35568e-133 (rank : 7)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	49
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH6_HUMAN
NC score	0.960920 (rank : 9)	θ value	2.77624e-142 (rank : 5)
Query Neighborhood Hits	148	Target Neighborhood Hits	222	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_HUMAN
NC score	0.951879 (rank : 10)	θ value	2.9938e-112 (rank : 11)
Query Neighborhood Hits	148	Target Neighborhood Hits	158	Shared Neighborhood Hits	62
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
NC score	0.951699 (rank : 11)	θ value	1.02895e-112 (rank : 10)
Query Neighborhood Hits	148	Target Neighborhood Hits	165	Shared Neighborhood Hits	62
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_MOUSE
NC score	0.950001 (rank : 12)	θ value	2.89973e-107 (rank : 12)
Query Neighborhood Hits	148	Target Neighborhood Hits	98	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH7_HUMAN
NC score	0.948978 (rank : 13)	θ value	3.54468e-105 (rank : 13)
Query Neighborhood Hits	148	Target Neighborhood Hits	107	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

CNGA2_MOUSE
NC score	0.806607 (rank : 14)	θ value	1.28732e-30 (rank : 17)
Query Neighborhood Hits	148	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA1_HUMAN
NC score	0.797659 (rank : 15)	θ value	1.6813e-30 (rank : 18)
Query Neighborhood Hits	148	Target Neighborhood Hits	149	Shared Neighborhood Hits	32
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
NC score	0.797070 (rank : 16)	θ value	4.42448e-31 (rank : 16)
Query Neighborhood Hits	148	Target Neighborhood Hits	84	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
NC score	0.793801 (rank : 17)	θ value	1.52067e-31 (rank : 15)
Query Neighborhood Hits	148	Target Neighborhood Hits	198	Shared Neighborhood Hits	33
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
NC score	0.793382 (rank : 18)	θ value	8.91499e-32 (rank : 14)
Query Neighborhood Hits	148	Target Neighborhood Hits	125	Shared Neighborhood Hits	33
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

HCN1_HUMAN
NC score	0.781330 (rank : 19)	θ value	2.42779e-29 (rank : 20)
Query Neighborhood Hits	148	Target Neighborhood Hits	120	Shared Neighborhood Hits	37
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
NC score	0.777668 (rank : 20)	θ value	2.42779e-29 (rank : 21)
Query Neighborhood Hits	148	Target Neighborhood Hits	172	Shared Neighborhood Hits	37
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN3_HUMAN
NC score	0.776507 (rank : 21)	θ value	1.12775e-26 (rank : 26)
Query Neighborhood Hits	148	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN3_MOUSE
NC score	0.775874 (rank : 22)	θ value	6.61148e-27 (rank : 25)
Query Neighborhood Hits	148	Target Neighborhood Hits	112	Shared Neighborhood Hits	37
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN2_MOUSE
NC score	0.767830 (rank : 23)	θ value	5.40856e-29 (rank : 22)
Query Neighborhood Hits	148	Target Neighborhood Hits	278	Shared Neighborhood Hits	58
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_HUMAN
NC score	0.765714 (rank : 24)	θ value	1.4233e-29 (rank : 19)
Query Neighborhood Hits	148	Target Neighborhood Hits	303	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
NC score	0.764949 (rank : 25)	θ value	5.40856e-29 (rank : 23)
Query Neighborhood Hits	148	Target Neighborhood Hits	284	Shared Neighborhood Hits	64
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_HUMAN
NC score	0.761466 (rank : 26)	θ value	7.06379e-29 (rank : 24)
Query Neighborhood Hits	148	Target Neighborhood Hits	369	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CNGB3_MOUSE
NC score	0.727910 (rank : 27)	θ value	4.91457e-14 (rank : 29)
Query Neighborhood Hits	148	Target Neighborhood Hits	74	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
NC score	0.717019 (rank : 28)	θ value	9.90251e-15 (rank : 28)
Query Neighborhood Hits	148	Target Neighborhood Hits	206	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB1_HUMAN
NC score	0.715553 (rank : 29)	θ value	3.63628e-17 (rank : 27)
Query Neighborhood Hits	148	Target Neighborhood Hits	222	Shared Neighborhood Hits	44
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNKH_HUMAN
NC score	0.249220 (rank : 30)	θ value	0.00175202 (rank : 30)
Query Neighborhood Hits	148	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNKF_HUMAN
NC score	0.189068 (rank : 31)	θ value	0.0193708 (rank : 33)
Query Neighborhood Hits	148	Target Neighborhood Hits	87	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNK3_HUMAN
NC score	0.182208 (rank : 32)	θ value	0.0113563 (rank : 32)
Query Neighborhood Hits	148	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK2_HUMAN
NC score	0.182061 (rank : 33)	θ value	0.0563607 (rank : 36)
Query Neighborhood Hits	148	Target Neighborhood Hits	86	Shared Neighborhood Hits	32
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
NC score	0.181386 (rank : 34)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	148	Target Neighborhood Hits	88	Shared Neighborhood Hits	32
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_MOUSE
NC score	0.178806 (rank : 35)	θ value	0.00869519 (rank : 31)
Query Neighborhood Hits	148	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNKA_HUMAN
NC score	0.174029 (rank : 36)	θ value	0.0431538 (rank : 34)
Query Neighborhood Hits	148	Target Neighborhood Hits	111	Shared Neighborhood Hits	34
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNK6_HUMAN
NC score	0.171806 (rank : 37)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	148	Target Neighborhood Hits	79	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNK4_HUMAN
NC score	0.166641 (rank : 38)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	148	Target Neighborhood Hits	109	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNKG_HUMAN
NC score	0.158686 (rank : 39)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	148	Target Neighborhood Hits	90	Shared Neighborhood Hits	30
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNK9_MOUSE
NC score	0.153184 (rank : 40)	θ value	0.279714 (rank : 47)
Query Neighborhood Hits	148	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCNK9_HUMAN
NC score	0.153035 (rank : 41)	θ value	0.279714 (rank : 46)
Query Neighborhood Hits	148	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK4_MOUSE
NC score	0.152361 (rank : 42)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	148	Target Neighborhood Hits	118	Shared Neighborhood Hits	35
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCNK1_HUMAN
NC score	0.126119 (rank : 43)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	148	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KAP0_HUMAN
NC score	0.126066 (rank : 44)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	148	Target Neighborhood Hits	52	Shared Neighborhood Hits	26
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KCNK5_HUMAN
NC score	0.125483 (rank : 45)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KCNK1_MOUSE
NC score	0.122328 (rank : 46)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	148	Target Neighborhood Hits	70	Shared Neighborhood Hits	37
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KAP0_MOUSE
NC score	0.115004 (rank : 47)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	148	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
NC score	0.104206 (rank : 48)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	148	Target Neighborhood Hits	58	Shared Neighborhood Hits	24
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
NC score	0.101834 (rank : 49)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	148	Target Neighborhood Hits	49	Shared Neighborhood Hits	24
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KCNKD_MOUSE
NC score	0.088200 (rank : 50)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	148	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KAP3_MOUSE
NC score	0.077118 (rank : 51)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	148	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP2_MOUSE
NC score	0.075813 (rank : 52)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	148	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_HUMAN
NC score	0.073902 (rank : 53)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	148	Target Neighborhood Hits	40	Shared Neighborhood Hits	19
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP2_HUMAN
NC score	0.073723 (rank : 54)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	148	Target Neighborhood Hits	48	Shared Neighborhood Hits	16
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KCNKD_HUMAN
NC score	0.070904 (rank : 55)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	148	Target Neighborhood Hits	58	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNK7_MOUSE
NC score	0.069353 (rank : 56)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	148	Target Neighborhood Hits	53	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNKC_HUMAN
NC score	0.066618 (rank : 57)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	148	Target Neighborhood Hits	51	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

CT152_MOUSE
NC score	0.059874 (rank : 58)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	148	Target Neighborhood Hits	38	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KCNK7_HUMAN
NC score	0.052615 (rank : 59)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	148	Target Neighborhood Hits	42	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCND1_MOUSE
NC score	0.046992 (rank : 60)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	148	Target Neighborhood Hits	165	Shared Neighborhood Hits	35
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

PSL1_HUMAN
NC score	0.043056 (rank : 61)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	148	Target Neighborhood Hits	650	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

KGP1B_HUMAN
NC score	0.042853 (rank : 62)	θ value	0.21417 (rank : 44)
Query Neighborhood Hits	148	Target Neighborhood Hits	921	Shared Neighborhood Hits	40
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
NC score	0.042800 (rank : 63)	θ value	0.21417 (rank : 43)
Query Neighborhood Hits	148	Target Neighborhood Hits	901	Shared Neighborhood Hits	40
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_MOUSE
NC score	0.042375 (rank : 64)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	148	Target Neighborhood Hits	922	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

NRX2B_HUMAN
NC score	0.040390 (rank : 65)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	148	Target Neighborhood Hits	481	Shared Neighborhood Hits	19
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

PRRT3_HUMAN
NC score	0.036709 (rank : 66)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	148	Target Neighborhood Hits	998	Shared Neighborhood Hits	46
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SAPS1_HUMAN
NC score	0.036260 (rank : 67)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	148	Target Neighborhood Hits	704	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

KCNN4_HUMAN
NC score	0.036259 (rank : 68)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	148	Target Neighborhood Hits	90	Shared Neighborhood Hits	27
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

EPN3_HUMAN
NC score	0.035038 (rank : 69)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	148	Target Neighborhood Hits	197	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

BSN_MOUSE
NC score	0.034905 (rank : 70)	θ value	0.279714 (rank : 45)
Query Neighborhood Hits	148	Target Neighborhood Hits	2057	Shared Neighborhood Hits	65
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MAGE1_HUMAN
NC score	0.034663 (rank : 71)	θ value	0.0961366 (rank : 39)
Query Neighborhood Hits	148	Target Neighborhood Hits	1389	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NACAM_MOUSE
NC score	0.034308 (rank : 72)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	148	Target Neighborhood Hits	1866	Shared Neighborhood Hits	69
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

KCNN4_MOUSE
NC score	0.033355 (rank : 73)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	148	Target Neighborhood Hits	85	Shared Neighborhood Hits	26
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

TS13_MOUSE
NC score	0.032954 (rank : 74)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	148	Target Neighborhood Hits	191	Shared Neighborhood Hits	6
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

JPH2_HUMAN
NC score	0.032166 (rank : 75)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	148	Target Neighborhood Hits	639	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MINP1_HUMAN
NC score	0.032146 (rank : 76)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	148	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNW1, O95172, O95286, Q59EJ2, Q9UGA3	Gene names	MINPP1, MIPP
Domain Architecture	No domain graphic available
Description	Multiple inositol polyphosphate phosphatase 1 precursor (EC 3.1.3.62) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase).

SC24C_HUMAN
NC score	0.031556 (rank : 77)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	148	Target Neighborhood Hits	662	Shared Neighborhood Hits	35
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

RGS3_MOUSE
NC score	0.030584 (rank : 78)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	148	Target Neighborhood Hits	1621	Shared Neighborhood Hits	55
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

NCOA6_HUMAN
NC score	0.028458 (rank : 79)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	148	Target Neighborhood Hits	1202	Shared Neighborhood Hits	47
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NRX2A_HUMAN
NC score	0.027013 (rank : 80)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	148	Target Neighborhood Hits	614	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

HAIR_HUMAN
NC score	0.026850 (rank : 81)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	148	Target Neighborhood Hits	172	Shared Neighborhood Hits	10
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

CEP68_HUMAN
NC score	0.025124 (rank : 82)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	148	Target Neighborhood Hits	128	Shared Neighborhood Hits	9
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

FA47B_HUMAN
NC score	0.024748 (rank : 83)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	148	Target Neighborhood Hits	431	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

PHLB1_MOUSE
NC score	0.023954 (rank : 84)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	148	Target Neighborhood Hits	678	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CXXC6_HUMAN
NC score	0.023436 (rank : 85)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	148	Target Neighborhood Hits	180	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

BIN1_HUMAN
NC score	0.023220 (rank : 86)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	148	Target Neighborhood Hits	335	Shared Neighborhood Hits	17
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

CKLF_HUMAN
NC score	0.022903 (rank : 87)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	148	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBR5, Q9UHM7, Q9UHN8, Q9UI41	Gene names	CKLF
Domain Architecture
Description	Chemokine-like factor (C32).

RTP3_MOUSE
NC score	0.021772 (rank : 88)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	148	Target Neighborhood Hits	374	Shared Neighborhood Hits	20
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

LCOR_MOUSE
NC score	0.021764 (rank : 89)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	148	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZPI3, Q3U302, Q5CZW7, Q80VA8, Q8BGT2, Q8C9Q0	Gene names	Lcor, Kiaa1795, Mlr2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

KCNN2_HUMAN
NC score	0.021593 (rank : 90)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	148	Target Neighborhood Hits	117	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
NC score	0.021570 (rank : 91)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	148	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

EPN3_MOUSE
NC score	0.020754 (rank : 92)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	148	Target Neighborhood Hits	312	Shared Neighborhood Hits	20
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

MUC1_HUMAN
NC score	0.020424 (rank : 93)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	148	Target Neighborhood Hits	975	Shared Neighborhood Hits	37
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

TAU_MOUSE
NC score	0.020381 (rank : 94)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	148	Target Neighborhood Hits	502	Shared Neighborhood Hits	29
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

BIN1_MOUSE
NC score	0.020321 (rank : 95)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	148	Target Neighborhood Hits	283	Shared Neighborhood Hits	19
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

CI079_HUMAN
NC score	0.020210 (rank : 96)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	148	Target Neighborhood Hits	288	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

LCOR_HUMAN
NC score	0.019948 (rank : 97)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	148	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JN0, Q5VW16, Q7Z723, Q86T32, Q86T33, Q8N3L6	Gene names	LCOR, KIAA1795, MLR2
Domain Architecture	No domain graphic available
Description	Ligand-dependent corepressor (LCoR) (Mblk1-related protein 2).

CCG8_MOUSE
NC score	0.019364 (rank : 98)	θ value	0.0563607 (rank : 35)
Query Neighborhood Hits	148	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHW2	Gene names	Cacng8
Domain Architecture
Description	Voltage-dependent calcium channel gamma-8 subunit (Neuronal voltage- gated calcium channel gamma-8 subunit).

NCOA6_MOUSE
NC score	0.018868 (rank : 99)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	148	Target Neighborhood Hits	1076	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NFH_MOUSE
NC score	0.018638 (rank : 100)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	148	Target Neighborhood Hits	2247	Shared Neighborhood Hits	62
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

DAB2_HUMAN
NC score	0.018446 (rank : 101)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	148	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

PSL1_MOUSE
NC score	0.018282 (rank : 102)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	148	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q3TD49, Q3TLQ8, Q3UG60, Q80VZ6	Gene names	Sppl2b
Domain Architecture	No domain graphic available
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b).

CHD5_HUMAN
NC score	0.018233 (rank : 103)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	148	Target Neighborhood Hits	349	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD4_MOUSE
NC score	0.017805 (rank : 104)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	148	Target Neighborhood Hits	408	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

TARA_MOUSE
NC score	0.017361 (rank : 105)	θ value	0.163984 (rank : 41)
Query Neighborhood Hits	148	Target Neighborhood Hits	1133	Shared Neighborhood Hits	29
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SON_HUMAN
NC score	0.017306 (rank : 106)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	148	Target Neighborhood Hits	1568	Shared Neighborhood Hits	41
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

FOXN1_HUMAN
NC score	0.017278 (rank : 107)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	148	Target Neighborhood Hits	377	Shared Neighborhood Hits	15
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

PDZD6_HUMAN
NC score	0.017252 (rank : 108)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	148	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

XKR7_MOUSE
NC score	0.017194 (rank : 109)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	148	Target Neighborhood Hits	146	Shared Neighborhood Hits	8
SwissProt Accessions	Q5GH64	Gene names	Xkr7, Xrg7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

CHD4_HUMAN
NC score	0.016928 (rank : 110)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	148	Target Neighborhood Hits	365	Shared Neighborhood Hits	8
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CMTA2_MOUSE
NC score	0.016866 (rank : 111)	θ value	1.38821 (rank : 68)
Query Neighborhood Hits	148	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CJ108_HUMAN
NC score	0.016114 (rank : 112)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	148	Target Neighborhood Hits	165	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

BICD1_HUMAN
NC score	0.015975 (rank : 113)	θ value	0.125558 (rank : 40)
Query Neighborhood Hits	148	Target Neighborhood Hits	844	Shared Neighborhood Hits	10
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

IRS2_MOUSE
NC score	0.015859 (rank : 114)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	148	Target Neighborhood Hits	248	Shared Neighborhood Hits	27
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

MILK1_MOUSE
NC score	0.015517 (rank : 115)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	148	Target Neighborhood Hits	788	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CHD3_HUMAN
NC score	0.015473 (rank : 116)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	148	Target Neighborhood Hits	397	Shared Neighborhood Hits	12
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

ZN703_HUMAN
NC score	0.014751 (rank : 117)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	148	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H7S9, Q5XG76	Gene names	ZNF703
Domain Architecture	No domain graphic available
Description	Zinc finger protein 703.

SENP3_MOUSE
NC score	0.014601 (rank : 118)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	148	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EP97	Gene names	Senp3, Smt3ip, Smt3ip1
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3) (Smt3-specific isopeptidase 1) (Smt3ip1).

EPN2_MOUSE
NC score	0.014473 (rank : 119)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	148	Target Neighborhood Hits	111	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CHU3, O70447, Q8BZ85	Gene names	Epn2
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2).

JPH2_MOUSE
NC score	0.013811 (rank : 120)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	148	Target Neighborhood Hits	279	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

FOXN1_MOUSE
NC score	0.013680 (rank : 121)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	148	Target Neighborhood Hits	300	Shared Neighborhood Hits	13
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

BICD1_MOUSE
NC score	0.012589 (rank : 122)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	148	Target Neighborhood Hits	837	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

JPH1_MOUSE
NC score	0.012519 (rank : 123)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	148	Target Neighborhood Hits	120	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ET80, Q9EQZ3	Gene names	Jph1, Jp1
Domain Architecture
Description	Junctophilin-1 (Junctophilin type 1) (JP-1).

GA2L2_MOUSE
NC score	0.012166 (rank : 124)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	148	Target Neighborhood Hits	395	Shared Neighborhood Hits	17
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

RP1L1_HUMAN
NC score	0.011729 (rank : 125)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	148	Target Neighborhood Hits	1072	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

CK056_HUMAN
NC score	0.011023 (rank : 126)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	148	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N612, Q9C0A4, Q9H0N3, Q9H624	Gene names	C11orf56, KIAA1759
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf56.

K0179_HUMAN
NC score	0.010943 (rank : 127)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	148	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q14684, Q8TBZ4	Gene names	KIAA0179
Domain Architecture
Description	Protein KIAA0179.

PK2L1_HUMAN
NC score	0.010698 (rank : 128)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	148	Target Neighborhood Hits	132	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

APXL_HUMAN
NC score	0.010323 (rank : 129)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	148	Target Neighborhood Hits	553	Shared Neighborhood Hits	21
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

LIMD1_MOUSE
NC score	0.010196 (rank : 130)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	148	Target Neighborhood Hits	291	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

MAP1B_MOUSE
NC score	0.010160 (rank : 131)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	148	Target Neighborhood Hits	977	Shared Neighborhood Hits	23
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

HD_HUMAN
NC score	0.009071 (rank : 132)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	148	Target Neighborhood Hits	165	Shared Neighborhood Hits	10
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

NBEA_MOUSE
NC score	0.008931 (rank : 133)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	148	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

NBEA_HUMAN
NC score	0.008818 (rank : 134)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	148	Target Neighborhood Hits	186	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

SEM6B_HUMAN
NC score	0.008367 (rank : 135)	θ value	0.62314 (rank : 62)
Query Neighborhood Hits	148	Target Neighborhood Hits	187	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

MAST4_HUMAN
NC score	0.007916 (rank : 136)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	148	Target Neighborhood Hits	1804	Shared Neighborhood Hits	55
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

ZN687_HUMAN
NC score	0.007406 (rank : 137)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	148	Target Neighborhood Hits	1244	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

WD21C_HUMAN
NC score	0.007335 (rank : 138)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	148	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NA75	Gene names	WDR21C
Domain Architecture	No domain graphic available
Description	WD repeat protein 21C.

CAC1B_MOUSE
NC score	0.007058 (rank : 139)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	148	Target Neighborhood Hits	351	Shared Neighborhood Hits	21
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

PLXB1_MOUSE
NC score	0.006715 (rank : 140)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	148	Target Neighborhood Hits	259	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

UBP42_HUMAN
NC score	0.006517 (rank : 141)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	148	Target Neighborhood Hits	445	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

INVS_MOUSE
NC score	0.006408 (rank : 142)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	148	Target Neighborhood Hits	609	Shared Neighborhood Hits	24
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

SUSD4_MOUSE
NC score	0.006143 (rank : 143)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	148	Target Neighborhood Hits	122	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

DUS2_HUMAN
NC score	0.005672 (rank : 144)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	148	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

EMID1_MOUSE
NC score	0.005194 (rank : 145)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	148	Target Neighborhood Hits	230	Shared Neighborhood Hits	17
SwissProt Accessions	Q91VF5	Gene names	Emid1, Emu1
Domain Architecture	No domain graphic available
Description	EMI domain-containing protein 1 precursor (Protein Emu1) (Emilin and multimerin domain-containing protein 1).

MAST2_HUMAN
NC score	0.004396 (rank : 146)	θ value	0.0736092 (rank : 38)
Query Neighborhood Hits	148	Target Neighborhood Hits	1189	Shared Neighborhood Hits	26
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

EPAS1_MOUSE
NC score	0.004394 (rank : 147)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	148	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

PANK1_MOUSE
NC score	0.003904 (rank : 148)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	148	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4K6, Q9D3K1, Q9QXM8	Gene names	Pank1, Pank
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (mPank1) (mPank).

PTC2_HUMAN
NC score	0.003762 (rank : 149)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	148	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

CAMKV_HUMAN
NC score	0.003255 (rank : 150)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	148	Target Neighborhood Hits	1084	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

OBSCN_HUMAN
NC score	0.001724 (rank : 151)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	148	Target Neighborhood Hits	1931	Shared Neighborhood Hits	42
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

DGKG_MOUSE
NC score	0.001362 (rank : 152)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	148	Target Neighborhood Hits	188	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

KKCC1_HUMAN
NC score	0.000567 (rank : 153)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	148	Target Neighborhood Hits	858	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N5S9, Q9BQH3	Gene names	CAMKK1, CAMKKA
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

KSR1_MOUSE
NC score	-0.000022 (rank : 154)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	148	Target Neighborhood Hits	870	Shared Neighborhood Hits	14
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

STK10_HUMAN
NC score	-0.000650 (rank : 155)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	148	Target Neighborhood Hits	1921	Shared Neighborhood Hits	26
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

M3K10_HUMAN
NC score	-0.000873 (rank : 156)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	148	Target Neighborhood Hits	1071	Shared Neighborhood Hits	22
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

VASN_HUMAN
NC score	-0.001514 (rank : 157)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	148	Target Neighborhood Hits	449	Shared Neighborhood Hits	7
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

EGR4_HUMAN
NC score	-0.002502 (rank : 158)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	148	Target Neighborhood Hits	939	Shared Neighborhood Hits	17
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

MTR1L_HUMAN
NC score	-0.002633 (rank : 159)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	148	Target Neighborhood Hits	1180	Shared Neighborhood Hits	12
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

ZF276_HUMAN
NC score	-0.002805 (rank : 160)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	148	Target Neighborhood Hits	768	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N554	Gene names	ZFP276
Domain Architecture	No domain graphic available
Description	Zinc finger protein 276 homolog (Zfp-276).

ZN227_HUMAN
NC score	-0.003956 (rank : 161)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	148	Target Neighborhood Hits	781	Shared Neighborhood Hits	7
SwissProt Accessions	Q86WZ6	Gene names	ZNF227
Domain Architecture	No domain graphic available
Description	Zinc finger protein 227.

ZN169_HUMAN
NC score	-0.004091 (rank : 162)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	148	Target Neighborhood Hits	764	Shared Neighborhood Hits	7
SwissProt Accessions	Q14929, Q6PI28	Gene names	ZNF169
Domain Architecture	No domain graphic available
Description	Zinc finger protein 169.