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Network neighborhood for query Sequence : KCNH6_HUMAN

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KCNH6_HUMAN
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KCNH2_HUMAN
θ value	0 (rank : 1)	NC score	0.979253 (rank : 5)
Query Neighborhood Hits	222	Target Neighborhood Hits	158	Shared Neighborhood Hits	73
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
θ value	0 (rank : 2)	NC score	0.979441 (rank : 4)
Query Neighborhood Hits	222	Target Neighborhood Hits	165	Shared Neighborhood Hits	77
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH6_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	222	Target Neighborhood Hits	222	Shared Neighborhood Hits	222
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH7_HUMAN
θ value	0 (rank : 4)	NC score	0.979920 (rank : 3)
Query Neighborhood Hits	222	Target Neighborhood Hits	107	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH7_MOUSE
θ value	0 (rank : 5)	NC score	0.980909 (rank : 2)
Query Neighborhood Hits	222	Target Neighborhood Hits	98	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH8_HUMAN
θ value	2.95243e-160 (rank : 6)	NC score	0.968133 (rank : 6)
Query Neighborhood Hits	222	Target Neighborhood Hits	104	Shared Neighborhood Hits	57
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH4_HUMAN
θ value	2.85966e-155 (rank : 7)	NC score	0.965650 (rank : 7)
Query Neighborhood Hits	222	Target Neighborhood Hits	177	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH3_HUMAN
θ value	2.77624e-142 (rank : 8)	NC score	0.960920 (rank : 9)
Query Neighborhood Hits	222	Target Neighborhood Hits	148	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
θ value	5.23575e-141 (rank : 9)	NC score	0.961308 (rank : 8)
Query Neighborhood Hits	222	Target Neighborhood Hits	133	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH1_HUMAN
θ value	9.24197e-138 (rank : 10)	NC score	0.960695 (rank : 13)
Query Neighborhood Hits	222	Target Neighborhood Hits	98	Shared Neighborhood Hits	63
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH1_MOUSE
θ value	2.689e-137 (rank : 11)	NC score	0.960807 (rank : 12)
Query Neighborhood Hits	222	Target Neighborhood Hits	94	Shared Neighborhood Hits	63
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH5_MOUSE
θ value	1.02182e-136 (rank : 12)	NC score	0.960894 (rank : 10)
Query Neighborhood Hits	222	Target Neighborhood Hits	102	Shared Neighborhood Hits	62
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
θ value	1.74296e-136 (rank : 13)	NC score	0.960872 (rank : 11)
Query Neighborhood Hits	222	Target Neighborhood Hits	99	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

HCN4_HUMAN
θ value	5.57106e-42 (rank : 14)	NC score	0.794141 (rank : 24)
Query Neighborhood Hits	222	Target Neighborhood Hits	303	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN2_MOUSE
θ value	1.3722e-40 (rank : 15)	NC score	0.797091 (rank : 23)
Query Neighborhood Hits	222	Target Neighborhood Hits	278	Shared Neighborhood Hits	58
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN2_HUMAN
θ value	1.79215e-40 (rank : 16)	NC score	0.791044 (rank : 26)
Query Neighborhood Hits	222	Target Neighborhood Hits	369	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN1_HUMAN
θ value	1.98146e-39 (rank : 17)	NC score	0.812057 (rank : 16)
Query Neighborhood Hits	222	Target Neighborhood Hits	120	Shared Neighborhood Hits	44
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
θ value	1.98146e-39 (rank : 18)	NC score	0.808345 (rank : 21)
Query Neighborhood Hits	222	Target Neighborhood Hits	172	Shared Neighborhood Hits	43
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN3_MOUSE
θ value	1.98146e-39 (rank : 19)	NC score	0.809402 (rank : 18)
Query Neighborhood Hits	222	Target Neighborhood Hits	112	Shared Neighborhood Hits	47
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN4_MOUSE
θ value	1.98146e-39 (rank : 20)	NC score	0.793216 (rank : 25)
Query Neighborhood Hits	222	Target Neighborhood Hits	284	Shared Neighborhood Hits	61
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN3_HUMAN
θ value	4.41421e-39 (rank : 21)	NC score	0.808384 (rank : 20)
Query Neighborhood Hits	222	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

CNGA2_MOUSE
θ value	4.13158e-37 (rank : 22)	NC score	0.823297 (rank : 14)
Query Neighborhood Hits	222	Target Neighborhood Hits	86	Shared Neighborhood Hits	43
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA1_HUMAN
θ value	1.20211e-36 (rank : 23)	NC score	0.813156 (rank : 15)
Query Neighborhood Hits	222	Target Neighborhood Hits	149	Shared Neighborhood Hits	41
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
θ value	2.26708e-35 (rank : 24)	NC score	0.808139 (rank : 22)
Query Neighborhood Hits	222	Target Neighborhood Hits	198	Shared Neighborhood Hits	44
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
θ value	1.6247e-33 (rank : 25)	NC score	0.808593 (rank : 19)
Query Neighborhood Hits	222	Target Neighborhood Hits	125	Shared Neighborhood Hits	42
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
θ value	1.37539e-32 (rank : 26)	NC score	0.811845 (rank : 17)
Query Neighborhood Hits	222	Target Neighborhood Hits	84	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGB3_MOUSE
θ value	7.32683e-18 (rank : 27)	NC score	0.749129 (rank : 27)
Query Neighborhood Hits	222	Target Neighborhood Hits	74	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
θ value	2.7842e-17 (rank : 28)	NC score	0.736560 (rank : 28)
Query Neighborhood Hits	222	Target Neighborhood Hits	206	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB1_HUMAN
θ value	8.95645e-16 (rank : 29)	NC score	0.729391 (rank : 29)
Query Neighborhood Hits	222	Target Neighborhood Hits	222	Shared Neighborhood Hits	44
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNKH_HUMAN
θ value	0.00102713 (rank : 30)	NC score	0.255770 (rank : 30)
Query Neighborhood Hits	222	Target Neighborhood Hits	89	Shared Neighborhood Hits	50
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KGP1A_HUMAN
θ value	0.00509761 (rank : 31)	NC score	0.050740 (rank : 71)
Query Neighborhood Hits	222	Target Neighborhood Hits	901	Shared Neighborhood Hits	51
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	0.00509761 (rank : 32)	NC score	0.050905 (rank : 70)
Query Neighborhood Hits	222	Target Neighborhood Hits	921	Shared Neighborhood Hits	53
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KCNKF_HUMAN
θ value	0.00665767 (rank : 33)	NC score	0.196393 (rank : 31)
Query Neighborhood Hits	222	Target Neighborhood Hits	87	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

GSCR1_HUMAN
θ value	0.0113563 (rank : 34)	NC score	0.048729 (rank : 75)
Query Neighborhood Hits	222	Target Neighborhood Hits	674	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

KGP1B_MOUSE
θ value	0.0113563 (rank : 35)	NC score	0.050489 (rank : 72)
Query Neighborhood Hits	222	Target Neighborhood Hits	922	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

PCLO_HUMAN
θ value	0.0113563 (rank : 36)	NC score	0.028751 (rank : 100)
Query Neighborhood Hits	222	Target Neighborhood Hits	2046	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

KCNK2_HUMAN
θ value	0.0148317 (rank : 37)	NC score	0.190377 (rank : 32)
Query Neighborhood Hits	222	Target Neighborhood Hits	86	Shared Neighborhood Hits	50
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	0.0148317 (rank : 38)	NC score	0.189702 (rank : 33)
Query Neighborhood Hits	222	Target Neighborhood Hits	88	Shared Neighborhood Hits	50
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_HUMAN
θ value	0.0193708 (rank : 39)	NC score	0.185557 (rank : 34)
Query Neighborhood Hits	222	Target Neighborhood Hits	88	Shared Neighborhood Hits	47
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK6_HUMAN
θ value	0.0193708 (rank : 40)	NC score	0.182324 (rank : 35)
Query Neighborhood Hits	222	Target Neighborhood Hits	79	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

PHLB1_HUMAN
θ value	0.0193708 (rank : 41)	NC score	0.037302 (rank : 87)
Query Neighborhood Hits	222	Target Neighborhood Hits	1038	Shared Neighborhood Hits	48
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

KCNK3_MOUSE
θ value	0.0330416 (rank : 42)	NC score	0.182191 (rank : 36)
Query Neighborhood Hits	222	Target Neighborhood Hits	93	Shared Neighborhood Hits	50
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

MAST2_MOUSE
θ value	0.0330416 (rank : 43)	NC score	0.007613 (rank : 179)
Query Neighborhood Hits	222	Target Neighborhood Hits	1110	Shared Neighborhood Hits	34
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

PHLB1_MOUSE
θ value	0.0330416 (rank : 44)	NC score	0.039067 (rank : 85)
Query Neighborhood Hits	222	Target Neighborhood Hits	678	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

TENS1_HUMAN
θ value	0.0330416 (rank : 45)	NC score	0.026718 (rank : 104)
Query Neighborhood Hits	222	Target Neighborhood Hits	400	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TESK1_HUMAN
θ value	0.0330416 (rank : 46)	NC score	0.006977 (rank : 187)
Query Neighborhood Hits	222	Target Neighborhood Hits	864	Shared Neighborhood Hits	22
SwissProt Accessions	Q15569	Gene names	TESK1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

CABIN_HUMAN
θ value	0.0431538 (rank : 47)	NC score	0.048979 (rank : 74)
Query Neighborhood Hits	222	Target Neighborhood Hits	490	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

TTP_HUMAN
θ value	0.0431538 (rank : 48)	NC score	0.029578 (rank : 99)
Query Neighborhood Hits	222	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

KCNKA_HUMAN
θ value	0.0563607 (rank : 49)	NC score	0.180760 (rank : 37)
Query Neighborhood Hits	222	Target Neighborhood Hits	111	Shared Neighborhood Hits	51
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

SALL2_MOUSE
θ value	0.0563607 (rank : 50)	NC score	0.006058 (rank : 194)
Query Neighborhood Hits	222	Target Neighborhood Hits	836	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QX96	Gene names	Sall2, Sal2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Spalt-like protein 2) (MSal-2).

ASPP1_MOUSE
θ value	0.0961366 (rank : 51)	NC score	0.016349 (rank : 138)
Query Neighborhood Hits	222	Target Neighborhood Hits	1244	Shared Neighborhood Hits	62
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

BSN_HUMAN
θ value	0.0961366 (rank : 52)	NC score	0.036337 (rank : 89)
Query Neighborhood Hits	222	Target Neighborhood Hits	1537	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

FA5_HUMAN
θ value	0.0961366 (rank : 53)	NC score	0.016906 (rank : 134)
Query Neighborhood Hits	222	Target Neighborhood Hits	172	Shared Neighborhood Hits	13
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

GLI1_HUMAN
θ value	0.163984 (rank : 54)	NC score	0.000875 (rank : 222)
Query Neighborhood Hits	222	Target Neighborhood Hits	828	Shared Neighborhood Hits	22
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

KCNK9_HUMAN
θ value	0.163984 (rank : 55)	NC score	0.157213 (rank : 43)
Query Neighborhood Hits	222	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK9_MOUSE
θ value	0.163984 (rank : 56)	NC score	0.157421 (rank : 42)
Query Neighborhood Hits	222	Target Neighborhood Hits	86	Shared Neighborhood Hits	49
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

PRP2_MOUSE
θ value	0.163984 (rank : 57)	NC score	0.036932 (rank : 88)
Query Neighborhood Hits	222	Target Neighborhood Hits	347	Shared Neighborhood Hits	38
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SC24C_HUMAN
θ value	0.163984 (rank : 58)	NC score	0.046685 (rank : 78)
Query Neighborhood Hits	222	Target Neighborhood Hits	662	Shared Neighborhood Hits	74
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

BAT2_MOUSE
θ value	0.21417 (rank : 59)	NC score	0.039743 (rank : 84)
Query Neighborhood Hits	222	Target Neighborhood Hits	947	Shared Neighborhood Hits	64
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

GP178_HUMAN
θ value	0.21417 (rank : 60)	NC score	0.036090 (rank : 90)
Query Neighborhood Hits	222	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2C4, Q5VTU1	Gene names	GPR178, KIAA1423
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR178.

K0773_HUMAN
θ value	0.21417 (rank : 61)	NC score	0.024088 (rank : 116)
Query Neighborhood Hits	222	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q86XD5, Q7L0D6, Q86T97	Gene names	KIAA0773
Domain Architecture	No domain graphic available
Description	Uncharacterized protein KIAA0773.

MLL2_HUMAN
θ value	0.21417 (rank : 62)	NC score	0.024545 (rank : 113)
Query Neighborhood Hits	222	Target Neighborhood Hits	1788	Shared Neighborhood Hits	87
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

TNIK_HUMAN
θ value	0.21417 (rank : 63)	NC score	0.004525 (rank : 203)
Query Neighborhood Hits	222	Target Neighborhood Hits	1570	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

ACK1_MOUSE
θ value	0.279714 (rank : 64)	NC score	0.004505 (rank : 204)
Query Neighborhood Hits	222	Target Neighborhood Hits	1080	Shared Neighborhood Hits	41
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

KCNKG_HUMAN
θ value	0.279714 (rank : 65)	NC score	0.169971 (rank : 39)
Query Neighborhood Hits	222	Target Neighborhood Hits	90	Shared Neighborhood Hits	50
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

WNK4_MOUSE
θ value	0.279714 (rank : 66)	NC score	0.007062 (rank : 185)
Query Neighborhood Hits	222	Target Neighborhood Hits	961	Shared Neighborhood Hits	35
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

FOXN1_HUMAN
θ value	0.365318 (rank : 67)	NC score	0.022473 (rank : 121)
Query Neighborhood Hits	222	Target Neighborhood Hits	377	Shared Neighborhood Hits	34
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

KCNK4_HUMAN
θ value	0.365318 (rank : 68)	NC score	0.170444 (rank : 38)
Query Neighborhood Hits	222	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNQ3_HUMAN
θ value	0.365318 (rank : 69)	NC score	0.059922 (rank : 67)
Query Neighborhood Hits	222	Target Neighborhood Hits	114	Shared Neighborhood Hits	46
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	0.365318 (rank : 70)	NC score	0.061490 (rank : 62)
Query Neighborhood Hits	222	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

SFRS8_HUMAN
θ value	0.365318 (rank : 71)	NC score	0.025161 (rank : 109)
Query Neighborhood Hits	222	Target Neighborhood Hits	166	Shared Neighborhood Hits	7
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

HEMGN_HUMAN
θ value	0.47712 (rank : 72)	NC score	0.023421 (rank : 118)
Query Neighborhood Hits	222	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BXL5, Q6XAR3, Q86XY5, Q9NPC0	Gene names	HEMGN, EDAG, NDR
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (Erythroid differentiation-associated gene protein) (EDAG-1).

SHAN2_HUMAN
θ value	0.47712 (rank : 73)	NC score	0.021163 (rank : 124)
Query Neighborhood Hits	222	Target Neighborhood Hits	346	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

TESK1_MOUSE
θ value	0.47712 (rank : 74)	NC score	0.005568 (rank : 197)
Query Neighborhood Hits	222	Target Neighborhood Hits	862	Shared Neighborhood Hits	20
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

KCND1_MOUSE
θ value	0.62314 (rank : 75)	NC score	0.068376 (rank : 59)
Query Neighborhood Hits	222	Target Neighborhood Hits	165	Shared Neighborhood Hits	52
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNK4_MOUSE
θ value	0.62314 (rank : 76)	NC score	0.159051 (rank : 40)
Query Neighborhood Hits	222	Target Neighborhood Hits	118	Shared Neighborhood Hits	53
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

MAP1A_HUMAN
θ value	0.62314 (rank : 77)	NC score	0.025641 (rank : 107)
Query Neighborhood Hits	222	Target Neighborhood Hits	1626	Shared Neighborhood Hits	73
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

RERE_HUMAN
θ value	0.62314 (rank : 78)	NC score	0.020138 (rank : 127)
Query Neighborhood Hits	222	Target Neighborhood Hits	779	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

AMOL2_MOUSE
θ value	0.813845 (rank : 79)	NC score	0.007942 (rank : 176)
Query Neighborhood Hits	222	Target Neighborhood Hits	591	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

ARI1B_HUMAN
θ value	0.813845 (rank : 80)	NC score	0.021577 (rank : 123)
Query Neighborhood Hits	222	Target Neighborhood Hits	567	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

BAT2_HUMAN
θ value	0.813845 (rank : 81)	NC score	0.040380 (rank : 82)
Query Neighborhood Hits	222	Target Neighborhood Hits	931	Shared Neighborhood Hits	74
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CMTA2_HUMAN
θ value	0.813845 (rank : 82)	NC score	0.014790 (rank : 140)
Query Neighborhood Hits	222	Target Neighborhood Hits	199	Shared Neighborhood Hits	9
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

IF4G1_MOUSE
θ value	0.813845 (rank : 83)	NC score	0.025414 (rank : 108)
Query Neighborhood Hits	222	Target Neighborhood Hits	534	Shared Neighborhood Hits	46
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

KCNB2_HUMAN
θ value	0.813845 (rank : 84)	NC score	0.031826 (rank : 95)
Query Neighborhood Hits	222	Target Neighborhood Hits	212	Shared Neighborhood Hits	42
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

WHRN_MOUSE
θ value	0.813845 (rank : 85)	NC score	0.011783 (rank : 154)
Query Neighborhood Hits	222	Target Neighborhood Hits	412	Shared Neighborhood Hits	25
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

CG026_HUMAN
θ value	1.06291 (rank : 86)	NC score	0.024921 (rank : 110)
Query Neighborhood Hits	222	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q96N11, Q9BQ43	Gene names	C7orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C7orf26.

K1802_HUMAN
θ value	1.06291 (rank : 87)	NC score	0.016498 (rank : 137)
Query Neighborhood Hits	222	Target Neighborhood Hits	1378	Shared Neighborhood Hits	71
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LR37B_HUMAN
θ value	1.06291 (rank : 88)	NC score	0.009867 (rank : 165)
Query Neighborhood Hits	222	Target Neighborhood Hits	392	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

MYCD_MOUSE
θ value	1.06291 (rank : 89)	NC score	0.018864 (rank : 131)
Query Neighborhood Hits	222	Target Neighborhood Hits	144	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

PELP1_MOUSE
θ value	1.06291 (rank : 90)	NC score	0.024307 (rank : 115)
Query Neighborhood Hits	222	Target Neighborhood Hits	709	Shared Neighborhood Hits	59
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PI5PA_HUMAN
θ value	1.06291 (rank : 91)	NC score	0.032992 (rank : 94)
Query Neighborhood Hits	222	Target Neighborhood Hits	749	Shared Neighborhood Hits	66
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

S23IP_MOUSE
θ value	1.06291 (rank : 92)	NC score	0.026275 (rank : 105)
Query Neighborhood Hits	222	Target Neighborhood Hits	363	Shared Neighborhood Hits	31
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

XRCC1_HUMAN
θ value	1.06291 (rank : 93)	NC score	0.016615 (rank : 135)
Query Neighborhood Hits	222	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	P18887, Q9HCB1	Gene names	XRCC1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ZN687_MOUSE
θ value	1.06291 (rank : 94)	NC score	0.001758 (rank : 216)
Query Neighborhood Hits	222	Target Neighborhood Hits	913	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

COAA1_HUMAN
θ value	1.38821 (rank : 95)	NC score	0.009769 (rank : 166)
Query Neighborhood Hits	222	Target Neighborhood Hits	316	Shared Neighborhood Hits	27
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

COEA1_MOUSE
θ value	1.38821 (rank : 96)	NC score	0.005598 (rank : 196)
Query Neighborhood Hits	222	Target Neighborhood Hits	402	Shared Neighborhood Hits	20
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

DMD_HUMAN
θ value	1.38821 (rank : 97)	NC score	0.005131 (rank : 199)
Query Neighborhood Hits	222	Target Neighborhood Hits	1135	Shared Neighborhood Hits	19
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
θ value	1.38821 (rank : 98)	NC score	0.004688 (rank : 202)
Query Neighborhood Hits	222	Target Neighborhood Hits	1111	Shared Neighborhood Hits	17
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

EP400_MOUSE
θ value	1.38821 (rank : 99)	NC score	0.013888 (rank : 145)
Query Neighborhood Hits	222	Target Neighborhood Hits	592	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

KAP0_MOUSE
θ value	1.38821 (rank : 100)	NC score	0.146252 (rank : 44)
Query Neighborhood Hits	222	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KCNB1_HUMAN
θ value	1.38821 (rank : 101)	NC score	0.030353 (rank : 96)
Query Neighborhood Hits	222	Target Neighborhood Hits	169	Shared Neighborhood Hits	38
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	1.38821 (rank : 102)	NC score	0.030231 (rank : 97)
Query Neighborhood Hits	222	Target Neighborhood Hits	154	Shared Neighborhood Hits	37
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCND1_HUMAN
θ value	1.38821 (rank : 103)	NC score	0.062641 (rank : 60)
Query Neighborhood Hits	222	Target Neighborhood Hits	160	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNK1_HUMAN
θ value	1.38821 (rank : 104)	NC score	0.133324 (rank : 46)
Query Neighborhood Hits	222	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNKD_MOUSE
θ value	1.38821 (rank : 105)	NC score	0.104547 (rank : 50)
Query Neighborhood Hits	222	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

LBXCO_HUMAN
θ value	1.38821 (rank : 106)	NC score	0.020342 (rank : 126)
Query Neighborhood Hits	222	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

MUCDL_MOUSE
θ value	1.38821 (rank : 107)	NC score	0.012660 (rank : 151)
Query Neighborhood Hits	222	Target Neighborhood Hits	461	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PER1_HUMAN
θ value	1.38821 (rank : 108)	NC score	0.010340 (rank : 162)
Query Neighborhood Hits	222	Target Neighborhood Hits	215	Shared Neighborhood Hits	16
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PO2F2_HUMAN
θ value	1.38821 (rank : 109)	NC score	0.007704 (rank : 178)
Query Neighborhood Hits	222	Target Neighborhood Hits	379	Shared Neighborhood Hits	17
SwissProt Accessions	P09086, Q16648, Q9BRS4	Gene names	POU2F2, OCT2, OTF2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

SF3B4_HUMAN
θ value	1.38821 (rank : 110)	NC score	0.012419 (rank : 152)
Query Neighborhood Hits	222	Target Neighborhood Hits	445	Shared Neighborhood Hits	29
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

ZN295_HUMAN
θ value	1.38821 (rank : 111)	NC score	-0.000379 (rank : 227)
Query Neighborhood Hits	222	Target Neighborhood Hits	847	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULJ3, Q6P4R0	Gene names	ZNF295, KIAA1227, ZBTB21
Domain Architecture
Description	Zinc finger protein 295 (Zinc finger and BTB domain-containing protein 21).

BCL9_MOUSE
θ value	1.81305 (rank : 112)	NC score	0.040357 (rank : 83)
Query Neighborhood Hits	222	Target Neighborhood Hits	770	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CG026_MOUSE
θ value	1.81305 (rank : 113)	NC score	0.023444 (rank : 117)
Query Neighborhood Hits	222	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGA7, Q3T9D0, Q8BN55	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C7orf26 homolog.

CK036_HUMAN
θ value	1.81305 (rank : 114)	NC score	0.028649 (rank : 101)
Query Neighborhood Hits	222	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q2M3A8, Q6TF48, Q8N7R8, Q8N9X7	Gene names	C11orf36
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf36.

CS007_MOUSE
θ value	1.81305 (rank : 115)	NC score	0.024375 (rank : 114)
Query Neighborhood Hits	222	Target Neighborhood Hits	464	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CSTFT_MOUSE
θ value	1.81305 (rank : 116)	NC score	0.006320 (rank : 193)
Query Neighborhood Hits	222	Target Neighborhood Hits	356	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

FBSH_HUMAN
θ value	1.81305 (rank : 117)	NC score	0.019124 (rank : 130)
Query Neighborhood Hits	222	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HAH7, Q96CI9, Q9H9X4	Gene names	FBS1, FBS
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

HES6_HUMAN
θ value	1.81305 (rank : 118)	NC score	0.012947 (rank : 147)
Query Neighborhood Hits	222	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q96HZ4, Q8N2J2, Q96T93, Q9P2S3	Gene names	HES6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1).

KCND2_HUMAN
θ value	1.81305 (rank : 119)	NC score	0.060683 (rank : 65)
Query Neighborhood Hits	222	Target Neighborhood Hits	154	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	1.81305 (rank : 120)	NC score	0.060671 (rank : 66)
Query Neighborhood Hits	222	Target Neighborhood Hits	156	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

UBP10_HUMAN
θ value	1.81305 (rank : 121)	NC score	0.008753 (rank : 170)
Query Neighborhood Hits	222	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

ZN207_HUMAN
θ value	1.81305 (rank : 122)	NC score	0.024807 (rank : 112)
Query Neighborhood Hits	222	Target Neighborhood Hits	326	Shared Neighborhood Hits	23
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ATN1_HUMAN
θ value	2.36792 (rank : 123)	NC score	0.027328 (rank : 103)
Query Neighborhood Hits	222	Target Neighborhood Hits	676	Shared Neighborhood Hits	53
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CSKI1_MOUSE
θ value	2.36792 (rank : 124)	NC score	0.012796 (rank : 149)
Query Neighborhood Hits	222	Target Neighborhood Hits	1031	Shared Neighborhood Hits	76
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DRD4_HUMAN
θ value	2.36792 (rank : 125)	NC score	-0.002279 (rank : 228)
Query Neighborhood Hits	222	Target Neighborhood Hits	886	Shared Neighborhood Hits	8
SwissProt Accessions	P21917	Gene names	DRD4
Domain Architecture
Description	D(4) dopamine receptor (Dopamine D4 receptor) (D(2C) dopamine receptor).

GRIN2_HUMAN
θ value	2.36792 (rank : 126)	NC score	0.016566 (rank : 136)
Query Neighborhood Hits	222	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	O60269, Q5SVF0	Gene names	GPRIN2, KIAA0514
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 2 (GRIN2).

KAP0_HUMAN
θ value	2.36792 (rank : 127)	NC score	0.157999 (rank : 41)
Query Neighborhood Hits	222	Target Neighborhood Hits	52	Shared Neighborhood Hits	34
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KCNK1_MOUSE
θ value	2.36792 (rank : 128)	NC score	0.129378 (rank : 49)
Query Neighborhood Hits	222	Target Neighborhood Hits	70	Shared Neighborhood Hits	44
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

RPGF4_HUMAN
θ value	2.36792 (rank : 129)	NC score	0.042961 (rank : 81)
Query Neighborhood Hits	222	Target Neighborhood Hits	88	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

RPGF4_MOUSE
θ value	2.36792 (rank : 130)	NC score	0.046732 (rank : 77)
Query Neighborhood Hits	222	Target Neighborhood Hits	80	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

RXRB_HUMAN
θ value	2.36792 (rank : 131)	NC score	0.003523 (rank : 208)
Query Neighborhood Hits	222	Target Neighborhood Hits	280	Shared Neighborhood Hits	21
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

WNK2_HUMAN
θ value	2.36792 (rank : 132)	NC score	0.008556 (rank : 172)
Query Neighborhood Hits	222	Target Neighborhood Hits	1407	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

YLPM1_HUMAN
θ value	2.36792 (rank : 133)	NC score	0.023003 (rank : 120)
Query Neighborhood Hits	222	Target Neighborhood Hits	670	Shared Neighborhood Hits	42
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

CO2A1_HUMAN
θ value	3.0926 (rank : 134)	NC score	0.009276 (rank : 168)
Query Neighborhood Hits	222	Target Neighborhood Hits	486	Shared Neighborhood Hits	39
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO4A2_MOUSE
θ value	3.0926 (rank : 135)	NC score	0.008717 (rank : 171)
Query Neighborhood Hits	222	Target Neighborhood Hits	492	Shared Neighborhood Hits	40
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

EP400_HUMAN
θ value	3.0926 (rank : 136)	NC score	0.012676 (rank : 150)
Query Neighborhood Hits	222	Target Neighborhood Hits	556	Shared Neighborhood Hits	35
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

GLYG2_HUMAN
θ value	3.0926 (rank : 137)	NC score	0.011453 (rank : 156)
Query Neighborhood Hits	222	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	O15488, O15485, O15486, O15487, O15489, O15490	Gene names	GYG2
Domain Architecture
Description	Glycogenin-2 (EC 2.4.1.186) (GN-2) (GN2).

HUNK_HUMAN
θ value	3.0926 (rank : 138)	NC score	0.002291 (rank : 213)
Query Neighborhood Hits	222	Target Neighborhood Hits	884	Shared Neighborhood Hits	18
SwissProt Accessions	P57058	Gene names	HUNK, MAKV
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19).

HXC4_HUMAN
θ value	3.0926 (rank : 139)	NC score	0.001210 (rank : 219)
Query Neighborhood Hits	222	Target Neighborhood Hits	361	Shared Neighborhood Hits	8
SwissProt Accessions	P09017	Gene names	HOXC4, HOX3E
Domain Architecture
Description	Homeobox protein Hox-C4 (Hox-3E) (CP19).

KCNF1_HUMAN
θ value	3.0926 (rank : 140)	NC score	0.029639 (rank : 98)
Query Neighborhood Hits	222	Target Neighborhood Hits	109	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNK5_HUMAN
θ value	3.0926 (rank : 141)	NC score	0.130761 (rank : 48)
Query Neighborhood Hits	222	Target Neighborhood Hits	102	Shared Neighborhood Hits	53
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

MDC1_MOUSE
θ value	3.0926 (rank : 142)	NC score	0.035149 (rank : 91)
Query Neighborhood Hits	222	Target Neighborhood Hits	998	Shared Neighborhood Hits	75
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MRCKG_HUMAN
θ value	3.0926 (rank : 143)	NC score	0.003385 (rank : 209)
Query Neighborhood Hits	222	Target Neighborhood Hits	1519	Shared Neighborhood Hits	28
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

PI5PA_MOUSE
θ value	3.0926 (rank : 144)	NC score	0.021675 (rank : 122)
Query Neighborhood Hits	222	Target Neighborhood Hits	331	Shared Neighborhood Hits	26
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PO2F2_MOUSE
θ value	3.0926 (rank : 145)	NC score	0.006500 (rank : 191)
Query Neighborhood Hits	222	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	Q00196, Q00197, Q00198, Q00199, Q00200, Q00201, Q05882, Q61995, Q61996, Q64245	Gene names	Pou2f2, Oct2, Otf2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

SFR15_HUMAN
θ value	3.0926 (rank : 146)	NC score	0.015210 (rank : 139)
Query Neighborhood Hits	222	Target Neighborhood Hits	368	Shared Neighborhood Hits	27
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

WBP11_MOUSE
θ value	3.0926 (rank : 147)	NC score	0.027336 (rank : 102)
Query Neighborhood Hits	222	Target Neighborhood Hits	362	Shared Neighborhood Hits	42
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

ZEP2_HUMAN
θ value	3.0926 (rank : 148)	NC score	0.002316 (rank : 212)
Query Neighborhood Hits	222	Target Neighborhood Hits	937	Shared Neighborhood Hits	29
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

CO3A1_MOUSE
θ value	4.03905 (rank : 149)	NC score	0.011232 (rank : 158)
Query Neighborhood Hits	222	Target Neighborhood Hits	466	Shared Neighborhood Hits	33
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CONA1_HUMAN
θ value	4.03905 (rank : 150)	NC score	0.007296 (rank : 183)
Query Neighborhood Hits	222	Target Neighborhood Hits	281	Shared Neighborhood Hits	21
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

COT1_MOUSE
θ value	4.03905 (rank : 151)	NC score	0.001753 (rank : 217)
Query Neighborhood Hits	222	Target Neighborhood Hits	160	Shared Neighborhood Hits	8
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

CSKI1_HUMAN
θ value	4.03905 (rank : 152)	NC score	0.010133 (rank : 164)
Query Neighborhood Hits	222	Target Neighborhood Hits	997	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DYN3_HUMAN
θ value	4.03905 (rank : 153)	NC score	0.006760 (rank : 189)
Query Neighborhood Hits	222	Target Neighborhood Hits	158	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

DYNA_HUMAN
θ value	4.03905 (rank : 154)	NC score	0.001973 (rank : 215)
Query Neighborhood Hits	222	Target Neighborhood Hits	1194	Shared Neighborhood Hits	24
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

GNAS1_HUMAN
θ value	4.03905 (rank : 155)	NC score	0.010313 (rank : 163)
Query Neighborhood Hits	222	Target Neighborhood Hits	278	Shared Neighborhood Hits	26
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

HXC4_MOUSE
θ value	4.03905 (rank : 156)	NC score	0.001067 (rank : 221)
Query Neighborhood Hits	222	Target Neighborhood Hits	365	Shared Neighborhood Hits	9
SwissProt Accessions	Q08624	Gene names	Hoxc4, Hox-3.5, Hoxc-4
Domain Architecture
Description	Homeobox protein Hox-C4 (Hox-3.5).

KCND3_HUMAN
θ value	4.03905 (rank : 157)	NC score	0.057932 (rank : 69)
Query Neighborhood Hits	222	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	4.03905 (rank : 158)	NC score	0.057964 (rank : 68)
Query Neighborhood Hits	222	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNK7_MOUSE
θ value	4.03905 (rank : 159)	NC score	0.079936 (rank : 57)
Query Neighborhood Hits	222	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNQ2_HUMAN
θ value	4.03905 (rank : 160)	NC score	0.045700 (rank : 79)
Query Neighborhood Hits	222	Target Neighborhood Hits	114	Shared Neighborhood Hits	45
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
θ value	4.03905 (rank : 161)	NC score	0.045579 (rank : 80)
Query Neighborhood Hits	222	Target Neighborhood Hits	163	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KLF3_MOUSE
θ value	4.03905 (rank : 162)	NC score	-0.003086 (rank : 229)
Query Neighborhood Hits	222	Target Neighborhood Hits	715	Shared Neighborhood Hits	13
SwissProt Accessions	Q60980	Gene names	Klf3, Bklf
Domain Architecture
Description	Krueppel-like factor 3 (Basic krueppel-like factor) (CACCC-box-binding protein BKLF) (TEF-2).

LBXCO_MOUSE
θ value	4.03905 (rank : 163)	NC score	0.014437 (rank : 142)
Query Neighborhood Hits	222	Target Neighborhood Hits	140	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BX46, Q3UYA4, Q5W8I2, Q8C0T2	Gene names	Lbxcor1, Corl1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1 (Transcriptional corepressor Corl1).

LHX1_MOUSE
θ value	4.03905 (rank : 164)	NC score	0.000416 (rank : 225)
Query Neighborhood Hits	222	Target Neighborhood Hits	453	Shared Neighborhood Hits	7
SwissProt Accessions	P63006, P36199	Gene names	Lhx1, Lim-1, Lim1
Domain Architecture	No domain graphic available
Description	LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1).

PRP1_HUMAN
θ value	4.03905 (rank : 165)	NC score	0.020019 (rank : 129)
Query Neighborhood Hits	222	Target Neighborhood Hits	385	Shared Neighborhood Hits	37
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

RUSC2_MOUSE
θ value	4.03905 (rank : 166)	NC score	0.018001 (rank : 132)
Query Neighborhood Hits	222	Target Neighborhood Hits	305	Shared Neighborhood Hits	30
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SRRM2_MOUSE
θ value	4.03905 (rank : 167)	NC score	0.038596 (rank : 86)
Query Neighborhood Hits	222	Target Neighborhood Hits	1470	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

WASF2_MOUSE
θ value	4.03905 (rank : 168)	NC score	0.014134 (rank : 143)
Query Neighborhood Hits	222	Target Neighborhood Hits	315	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WBP11_HUMAN
θ value	4.03905 (rank : 169)	NC score	0.024896 (rank : 111)
Query Neighborhood Hits	222	Target Neighborhood Hits	354	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

3BHS7_MOUSE
θ value	5.27518 (rank : 170)	NC score	0.010340 (rank : 161)
Query Neighborhood Hits	222	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQC1	Gene names	Hsd3b7
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase type 7 (3 beta-hydroxysteroid dehydrogenase type VII) (3Beta-HSD VII) (3-beta-hydroxy-delta(5)-C27 steroid oxidoreductase) (EC 1.1.1.-) (C(27) 3beta-HSD).

B3A3_HUMAN
θ value	5.27518 (rank : 171)	NC score	0.007064 (rank : 184)
Query Neighborhood Hits	222	Target Neighborhood Hits	119	Shared Neighborhood Hits	15
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

BCL9_HUMAN
θ value	5.27518 (rank : 172)	NC score	0.047490 (rank : 76)
Query Neighborhood Hits	222	Target Neighborhood Hits	1008	Shared Neighborhood Hits	84
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CSPG3_HUMAN
θ value	5.27518 (rank : 173)	NC score	0.000647 (rank : 224)
Query Neighborhood Hits	222	Target Neighborhood Hits	676	Shared Neighborhood Hits	21
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

FOXN4_HUMAN
θ value	5.27518 (rank : 174)	NC score	0.007436 (rank : 180)
Query Neighborhood Hits	222	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

KAP1_HUMAN
θ value	5.27518 (rank : 175)	NC score	0.133607 (rank : 45)
Query Neighborhood Hits	222	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
θ value	5.27518 (rank : 176)	NC score	0.131276 (rank : 47)
Query Neighborhood Hits	222	Target Neighborhood Hits	49	Shared Neighborhood Hits	32
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KCMA1_HUMAN
θ value	5.27518 (rank : 177)	NC score	0.061294 (rank : 64)
Query Neighborhood Hits	222	Target Neighborhood Hits	96	Shared Neighborhood Hits	40
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCMA1_MOUSE
θ value	5.27518 (rank : 178)	NC score	0.061412 (rank : 63)
Query Neighborhood Hits	222	Target Neighborhood Hits	94	Shared Neighborhood Hits	40
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCNG3_MOUSE
θ value	5.27518 (rank : 179)	NC score	0.020136 (rank : 128)
Query Neighborhood Hits	222	Target Neighborhood Hits	91	Shared Neighborhood Hits	23
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNKC_HUMAN
θ value	5.27518 (rank : 180)	NC score	0.082058 (rank : 56)
Query Neighborhood Hits	222	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

MAGC1_HUMAN
θ value	5.27518 (rank : 181)	NC score	0.006043 (rank : 195)
Query Neighborhood Hits	222	Target Neighborhood Hits	431	Shared Neighborhood Hits	24
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MGR5_HUMAN
θ value	5.27518 (rank : 182)	NC score	0.002824 (rank : 211)
Query Neighborhood Hits	222	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

MISS_MOUSE
θ value	5.27518 (rank : 183)	NC score	0.033253 (rank : 93)
Query Neighborhood Hits	222	Target Neighborhood Hits	444	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MLL4_HUMAN
θ value	5.27518 (rank : 184)	NC score	0.013948 (rank : 144)
Query Neighborhood Hits	222	Target Neighborhood Hits	722	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PANK1_HUMAN
θ value	5.27518 (rank : 185)	NC score	0.007349 (rank : 182)
Query Neighborhood Hits	222	Target Neighborhood Hits	75	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TE04, Q7RTX6, Q7Z495, Q8TBQ8	Gene names	PANK1, PANK
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (hPanK1) (hPanK).

PRDM2_HUMAN
θ value	5.27518 (rank : 186)	NC score	0.001203 (rank : 220)
Query Neighborhood Hits	222	Target Neighborhood Hits	1135	Shared Neighborhood Hits	37
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

PTC1_HUMAN
θ value	5.27518 (rank : 187)	NC score	0.005373 (rank : 198)
Query Neighborhood Hits	222	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q13635, Q13463, Q5VZC0	Gene names	PTCH1, PTCH
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

RASF7_HUMAN
θ value	5.27518 (rank : 188)	NC score	0.009451 (rank : 167)
Query Neighborhood Hits	222	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q02833	Gene names	RASSF7, C11orf13, HRC1
Domain Architecture
Description	Ras association domain-containing protein 7 (HRAS1-related cluster protein 1).

SAM14_HUMAN
θ value	5.27518 (rank : 189)	NC score	0.011252 (rank : 157)
Query Neighborhood Hits	222	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SMCA4_HUMAN
θ value	5.27518 (rank : 190)	NC score	0.006762 (rank : 188)
Query Neighborhood Hits	222	Target Neighborhood Hits	597	Shared Neighborhood Hits	34
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

ST5_HUMAN
θ value	5.27518 (rank : 191)	NC score	0.004785 (rank : 201)
Query Neighborhood Hits	222	Target Neighborhood Hits	151	Shared Neighborhood Hits	9
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

SYN2_MOUSE
θ value	5.27518 (rank : 192)	NC score	0.007840 (rank : 177)
Query Neighborhood Hits	222	Target Neighborhood Hits	183	Shared Neighborhood Hits	20
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

TEX14_HUMAN
θ value	5.27518 (rank : 193)	NC score	0.008048 (rank : 175)
Query Neighborhood Hits	222	Target Neighborhood Hits	1103	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

VINC_HUMAN
θ value	5.27518 (rank : 194)	NC score	0.013494 (rank : 146)
Query Neighborhood Hits	222	Target Neighborhood Hits	145	Shared Neighborhood Hits	6
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

VINC_MOUSE
θ value	5.27518 (rank : 195)	NC score	0.011991 (rank : 153)
Query Neighborhood Hits	222	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	Q64727, Q8BP32, Q8BS46, Q922C5, Q922D9	Gene names	Vcl
Domain Architecture
Description	Vinculin (Metavinculin).

CNOT3_HUMAN
θ value	6.88961 (rank : 196)	NC score	0.008877 (rank : 169)
Query Neighborhood Hits	222	Target Neighborhood Hits	425	Shared Neighborhood Hits	22
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

K1802_MOUSE
θ value	6.88961 (rank : 197)	NC score	0.023318 (rank : 119)
Query Neighborhood Hits	222	Target Neighborhood Hits	1596	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KCNKD_HUMAN
θ value	6.88961 (rank : 198)	NC score	0.084490 (rank : 55)
Query Neighborhood Hits	222	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

PAK4_MOUSE
θ value	6.88961 (rank : 199)	NC score	0.004472 (rank : 205)
Query Neighborhood Hits	222	Target Neighborhood Hits	1098	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

TFE2_HUMAN
θ value	6.88961 (rank : 200)	NC score	0.007350 (rank : 181)
Query Neighborhood Hits	222	Target Neighborhood Hits	161	Shared Neighborhood Hits	14
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

ZC3H6_HUMAN
θ value	6.88961 (rank : 201)	NC score	0.010391 (rank : 160)
Query Neighborhood Hits	222	Target Neighborhood Hits	228	Shared Neighborhood Hits	20
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ZEP2_MOUSE
θ value	6.88961 (rank : 202)	NC score	0.001424 (rank : 218)
Query Neighborhood Hits	222	Target Neighborhood Hits	964	Shared Neighborhood Hits	31
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

ATS14_HUMAN
θ value	8.99809 (rank : 203)	NC score	0.002239 (rank : 214)
Query Neighborhood Hits	222	Target Neighborhood Hits	382	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

CBP_HUMAN
θ value	8.99809 (rank : 204)	NC score	0.017275 (rank : 133)
Query Neighborhood Hits	222	Target Neighborhood Hits	941	Shared Neighborhood Hits	63
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CJ012_HUMAN
θ value	8.99809 (rank : 205)	NC score	0.014671 (rank : 141)
Query Neighborhood Hits	222	Target Neighborhood Hits	467	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CLIC6_MOUSE
θ value	8.99809 (rank : 206)	NC score	0.003258 (rank : 210)
Query Neighborhood Hits	222	Target Neighborhood Hits	134	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BHB9	Gene names	Clic6
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CO4A1_MOUSE
θ value	8.99809 (rank : 207)	NC score	0.008269 (rank : 173)
Query Neighborhood Hits	222	Target Neighborhood Hits	450	Shared Neighborhood Hits	40
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

CRTC1_HUMAN
θ value	8.99809 (rank : 208)	NC score	0.021128 (rank : 125)
Query Neighborhood Hits	222	Target Neighborhood Hits	319	Shared Neighborhood Hits	43
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

FXL16_HUMAN
θ value	8.99809 (rank : 209)	NC score	0.003989 (rank : 206)
Query Neighborhood Hits	222	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

GON4L_HUMAN
θ value	8.99809 (rank : 210)	NC score	0.010527 (rank : 159)
Query Neighborhood Hits	222	Target Neighborhood Hits	555	Shared Neighborhood Hits	25
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

GP152_MOUSE
θ value	8.99809 (rank : 211)	NC score	0.007015 (rank : 186)
Query Neighborhood Hits	222	Target Neighborhood Hits	607	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

KCNN4_HUMAN
θ value	8.99809 (rank : 212)	NC score	0.034054 (rank : 92)
Query Neighborhood Hits	222	Target Neighborhood Hits	90	Shared Neighborhood Hits	41
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

LPIN3_MOUSE
θ value	8.99809 (rank : 213)	NC score	0.003600 (rank : 207)
Query Neighborhood Hits	222	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PI4, Q3TQ75, Q8C7R9	Gene names	Lpin3
Domain Architecture
Description	Lipin-3.

MBRL_MOUSE
θ value	8.99809 (rank : 214)	NC score	0.006397 (rank : 192)
Query Neighborhood Hits	222	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIV2, Q68EE1, Q6KAN7, Q7TS84, Q8CIV1, Q99K29	Gene names	ORF61
Domain Architecture	No domain graphic available
Description	Membralin.

RAVR1_MOUSE
θ value	8.99809 (rank : 215)	NC score	0.004920 (rank : 200)
Query Neighborhood Hits	222	Target Neighborhood Hits	179	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

RPGF3_HUMAN
θ value	8.99809 (rank : 216)	NC score	0.025947 (rank : 106)
Query Neighborhood Hits	222	Target Neighborhood Hits	56	Shared Neighborhood Hits	18
SwissProt Accessions	O95398, O95634, Q8WVN0	Gene names	RAPGEF3, CGEF1, EPAC, EPAC1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).

RPGF6_HUMAN
θ value	8.99809 (rank : 217)	NC score	0.008082 (rank : 174)
Query Neighborhood Hits	222	Target Neighborhood Hits	266	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

SHAN2_MOUSE
θ value	8.99809 (rank : 218)	NC score	0.011732 (rank : 155)
Query Neighborhood Hits	222	Target Neighborhood Hits	446	Shared Neighborhood Hits	17
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SRBP1_HUMAN
θ value	8.99809 (rank : 219)	NC score	0.006511 (rank : 190)
Query Neighborhood Hits	222	Target Neighborhood Hits	225	Shared Neighborhood Hits	19
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TRIO_HUMAN
θ value	8.99809 (rank : 220)	NC score	0.000770 (rank : 223)
Query Neighborhood Hits	222	Target Neighborhood Hits	1580	Shared Neighborhood Hits	32
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

WASF4_HUMAN
θ value	8.99809 (rank : 221)	NC score	0.012934 (rank : 148)
Query Neighborhood Hits	222	Target Neighborhood Hits	282	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

ZN438_HUMAN
θ value	8.99809 (rank : 222)	NC score	0.000162 (rank : 226)
Query Neighborhood Hits	222	Target Neighborhood Hits	906	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

CT152_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.072768 (rank : 58)
Query Neighborhood Hits	222	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KAP2_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.094826 (rank : 53)
Query Neighborhood Hits	222	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.097164 (rank : 52)
Query Neighborhood Hits	222	Target Neighborhood Hits	44	Shared Neighborhood Hits	24
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.093965 (rank : 54)
Query Neighborhood Hits	222	Target Neighborhood Hits	40	Shared Neighborhood Hits	27
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.097377 (rank : 51)
Query Neighborhood Hits	222	Target Neighborhood Hits	43	Shared Neighborhood Hits	27
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KCNK7_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.061614 (rank : 61)
Query Neighborhood Hits	222	Target Neighborhood Hits	42	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

OGFR_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.050317 (rank : 73)
Query Neighborhood Hits	222	Target Neighborhood Hits	1582	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

Hits sorted by NC score

KCNH6_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	222	Target Neighborhood Hits	222	Shared Neighborhood Hits	222
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH7_MOUSE
NC score	0.980909 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	222	Target Neighborhood Hits	98	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH7_HUMAN
NC score	0.979920 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	222	Target Neighborhood Hits	107	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH2_MOUSE
NC score	0.979441 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	222	Target Neighborhood Hits	165	Shared Neighborhood Hits	77
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH2_HUMAN
NC score	0.979253 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	222	Target Neighborhood Hits	158	Shared Neighborhood Hits	73
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH8_HUMAN
NC score	0.968133 (rank : 6)	θ value	2.95243e-160 (rank : 6)
Query Neighborhood Hits	222	Target Neighborhood Hits	104	Shared Neighborhood Hits	57
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH4_HUMAN
NC score	0.965650 (rank : 7)	θ value	2.85966e-155 (rank : 7)
Query Neighborhood Hits	222	Target Neighborhood Hits	177	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH3_MOUSE
NC score	0.961308 (rank : 8)	θ value	5.23575e-141 (rank : 9)
Query Neighborhood Hits	222	Target Neighborhood Hits	133	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH3_HUMAN
NC score	0.960920 (rank : 9)	θ value	2.77624e-142 (rank : 8)
Query Neighborhood Hits	222	Target Neighborhood Hits	148	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH5_MOUSE
NC score	0.960894 (rank : 10)	θ value	1.02182e-136 (rank : 12)
Query Neighborhood Hits	222	Target Neighborhood Hits	102	Shared Neighborhood Hits	62
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
NC score	0.960872 (rank : 11)	θ value	1.74296e-136 (rank : 13)
Query Neighborhood Hits	222	Target Neighborhood Hits	99	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH1_MOUSE
NC score	0.960807 (rank : 12)	θ value	2.689e-137 (rank : 11)
Query Neighborhood Hits	222	Target Neighborhood Hits	94	Shared Neighborhood Hits	63
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.960695 (rank : 13)	θ value	9.24197e-138 (rank : 10)
Query Neighborhood Hits	222	Target Neighborhood Hits	98	Shared Neighborhood Hits	63
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

CNGA2_MOUSE
NC score	0.823297 (rank : 14)	θ value	4.13158e-37 (rank : 22)
Query Neighborhood Hits	222	Target Neighborhood Hits	86	Shared Neighborhood Hits	43
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA1_HUMAN
NC score	0.813156 (rank : 15)	θ value	1.20211e-36 (rank : 23)
Query Neighborhood Hits	222	Target Neighborhood Hits	149	Shared Neighborhood Hits	41
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

HCN1_HUMAN
NC score	0.812057 (rank : 16)	θ value	1.98146e-39 (rank : 17)
Query Neighborhood Hits	222	Target Neighborhood Hits	120	Shared Neighborhood Hits	44
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

CNGA3_MOUSE
NC score	0.811845 (rank : 17)	θ value	1.37539e-32 (rank : 26)
Query Neighborhood Hits	222	Target Neighborhood Hits	84	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

HCN3_MOUSE
NC score	0.809402 (rank : 18)	θ value	1.98146e-39 (rank : 19)
Query Neighborhood Hits	222	Target Neighborhood Hits	112	Shared Neighborhood Hits	47
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

CNGA3_HUMAN
NC score	0.808593 (rank : 19)	θ value	1.6247e-33 (rank : 25)
Query Neighborhood Hits	222	Target Neighborhood Hits	125	Shared Neighborhood Hits	42
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

HCN3_HUMAN
NC score	0.808384 (rank : 20)	θ value	4.41421e-39 (rank : 21)
Query Neighborhood Hits	222	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN1_MOUSE
NC score	0.808345 (rank : 21)	θ value	1.98146e-39 (rank : 18)
Query Neighborhood Hits	222	Target Neighborhood Hits	172	Shared Neighborhood Hits	43
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

CNGA1_MOUSE
NC score	0.808139 (rank : 22)	θ value	2.26708e-35 (rank : 24)
Query Neighborhood Hits	222	Target Neighborhood Hits	198	Shared Neighborhood Hits	44
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

HCN2_MOUSE
NC score	0.797091 (rank : 23)	θ value	1.3722e-40 (rank : 15)
Query Neighborhood Hits	222	Target Neighborhood Hits	278	Shared Neighborhood Hits	58
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_HUMAN
NC score	0.794141 (rank : 24)	θ value	5.57106e-42 (rank : 14)
Query Neighborhood Hits	222	Target Neighborhood Hits	303	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
NC score	0.793216 (rank : 25)	θ value	1.98146e-39 (rank : 20)
Query Neighborhood Hits	222	Target Neighborhood Hits	284	Shared Neighborhood Hits	61
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_HUMAN
NC score	0.791044 (rank : 26)	θ value	1.79215e-40 (rank : 16)
Query Neighborhood Hits	222	Target Neighborhood Hits	369	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CNGB3_MOUSE
NC score	0.749129 (rank : 27)	θ value	7.32683e-18 (rank : 27)
Query Neighborhood Hits	222	Target Neighborhood Hits	74	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
NC score	0.736560 (rank : 28)	θ value	2.7842e-17 (rank : 28)
Query Neighborhood Hits	222	Target Neighborhood Hits	206	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB1_HUMAN
NC score	0.729391 (rank : 29)	θ value	8.95645e-16 (rank : 29)
Query Neighborhood Hits	222	Target Neighborhood Hits	222	Shared Neighborhood Hits	44
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNKH_HUMAN
NC score	0.255770 (rank : 30)	θ value	0.00102713 (rank : 30)
Query Neighborhood Hits	222	Target Neighborhood Hits	89	Shared Neighborhood Hits	50
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNKF_HUMAN
NC score	0.196393 (rank : 31)	θ value	0.00665767 (rank : 33)
Query Neighborhood Hits	222	Target Neighborhood Hits	87	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNK2_HUMAN
NC score	0.190377 (rank : 32)	θ value	0.0148317 (rank : 37)
Query Neighborhood Hits	222	Target Neighborhood Hits	86	Shared Neighborhood Hits	50
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
NC score	0.189702 (rank : 33)	θ value	0.0148317 (rank : 38)
Query Neighborhood Hits	222	Target Neighborhood Hits	88	Shared Neighborhood Hits	50
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_HUMAN
NC score	0.185557 (rank : 34)	θ value	0.0193708 (rank : 39)
Query Neighborhood Hits	222	Target Neighborhood Hits	88	Shared Neighborhood Hits	47
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK6_HUMAN
NC score	0.182324 (rank : 35)	θ value	0.0193708 (rank : 40)
Query Neighborhood Hits	222	Target Neighborhood Hits	79	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNK3_MOUSE
NC score	0.182191 (rank : 36)	θ value	0.0330416 (rank : 42)
Query Neighborhood Hits	222	Target Neighborhood Hits	93	Shared Neighborhood Hits	50
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNKA_HUMAN
NC score	0.180760 (rank : 37)	θ value	0.0563607 (rank : 49)
Query Neighborhood Hits	222	Target Neighborhood Hits	111	Shared Neighborhood Hits	51
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNK4_HUMAN
NC score	0.170444 (rank : 38)	θ value	0.365318 (rank : 68)
Query Neighborhood Hits	222	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNKG_HUMAN
NC score	0.169971 (rank : 39)	θ value	0.279714 (rank : 65)
Query Neighborhood Hits	222	Target Neighborhood Hits	90	Shared Neighborhood Hits	50
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNK4_MOUSE
NC score	0.159051 (rank : 40)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	222	Target Neighborhood Hits	118	Shared Neighborhood Hits	53
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KAP0_HUMAN
NC score	0.157999 (rank : 41)	θ value	2.36792 (rank : 127)
Query Neighborhood Hits	222	Target Neighborhood Hits	52	Shared Neighborhood Hits	34
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KCNK9_MOUSE
NC score	0.157421 (rank : 42)	θ value	0.163984 (rank : 56)
Query Neighborhood Hits	222	Target Neighborhood Hits	86	Shared Neighborhood Hits	49
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCNK9_HUMAN
NC score	0.157213 (rank : 43)	θ value	0.163984 (rank : 55)
Query Neighborhood Hits	222	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KAP0_MOUSE
NC score	0.146252 (rank : 44)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	222	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
NC score	0.133607 (rank : 45)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	222	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KCNK1_HUMAN
NC score	0.133324 (rank : 46)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	222	Target Neighborhood Hits	68	Shared Neighborhood Hits	45
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KAP1_MOUSE
NC score	0.131276 (rank : 47)	θ value	5.27518 (rank : 176)
Query Neighborhood Hits	222	Target Neighborhood Hits	49	Shared Neighborhood Hits	32
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KCNK5_HUMAN
NC score	0.130761 (rank : 48)	θ value	3.0926 (rank : 141)
Query Neighborhood Hits	222	Target Neighborhood Hits	102	Shared Neighborhood Hits	53
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KCNK1_MOUSE
NC score	0.129378 (rank : 49)	θ value	2.36792 (rank : 128)
Query Neighborhood Hits	222	Target Neighborhood Hits	70	Shared Neighborhood Hits	44
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KCNKD_MOUSE
NC score	0.104547 (rank : 50)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	222	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KAP3_MOUSE
NC score	0.097377 (rank : 51)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	222	Target Neighborhood Hits	43	Shared Neighborhood Hits	27
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP2_MOUSE
NC score	0.097164 (rank : 52)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	222	Target Neighborhood Hits	44	Shared Neighborhood Hits	24
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_HUMAN
NC score	0.094826 (rank : 53)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	222	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_HUMAN
NC score	0.093965 (rank : 54)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	222	Target Neighborhood Hits	40	Shared Neighborhood Hits	27
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KCNKD_HUMAN
NC score	0.084490 (rank : 55)	θ value	6.88961 (rank : 198)
Query Neighborhood Hits	222	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNKC_HUMAN
NC score	0.082058 (rank : 56)	θ value	5.27518 (rank : 180)
Query Neighborhood Hits	222	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

KCNK7_MOUSE
NC score	0.079936 (rank : 57)	θ value	4.03905 (rank : 159)
Query Neighborhood Hits	222	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

CT152_MOUSE
NC score	0.072768 (rank : 58)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	222	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KCND1_MOUSE
NC score	0.068376 (rank : 59)	θ value	0.62314 (rank : 75)
Query Neighborhood Hits	222	Target Neighborhood Hits	165	Shared Neighborhood Hits	52
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
NC score	0.062641 (rank : 60)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	222	Target Neighborhood Hits	160	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNK7_HUMAN
NC score	0.061614 (rank : 61)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	222	Target Neighborhood Hits	42	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCNQ3_MOUSE
NC score	0.061490 (rank : 62)	θ value	0.365318 (rank : 70)
Query Neighborhood Hits	222	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCMA1_MOUSE
NC score	0.061412 (rank : 63)	θ value	5.27518 (rank : 178)
Query Neighborhood Hits	222	Target Neighborhood Hits	94	Shared Neighborhood Hits	40
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCMA1_HUMAN
NC score	0.061294 (rank : 64)	θ value	5.27518 (rank : 177)
Query Neighborhood Hits	222	Target Neighborhood Hits	96	Shared Neighborhood Hits	40
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCND2_HUMAN
NC score	0.060683 (rank : 65)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	222	Target Neighborhood Hits	154	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
NC score	0.060671 (rank : 66)	θ value	1.81305 (rank : 120)
Query Neighborhood Hits	222	Target Neighborhood Hits	156	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCNQ3_HUMAN
NC score	0.059922 (rank : 67)	θ value	0.365318 (rank : 69)
Query Neighborhood Hits	222	Target Neighborhood Hits	114	Shared Neighborhood Hits	46
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCND3_MOUSE
NC score	0.057964 (rank : 68)	θ value	4.03905 (rank : 158)
Query Neighborhood Hits	222	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.057932 (rank : 69)	θ value	4.03905 (rank : 157)
Query Neighborhood Hits	222	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KGP1B_HUMAN
NC score	0.050905 (rank : 70)	θ value	0.00509761 (rank : 32)
Query Neighborhood Hits	222	Target Neighborhood Hits	921	Shared Neighborhood Hits	53
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
NC score	0.050740 (rank : 71)	θ value	0.00509761 (rank : 31)
Query Neighborhood Hits	222	Target Neighborhood Hits	901	Shared Neighborhood Hits	51
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_MOUSE
NC score	0.050489 (rank : 72)	θ value	0.0113563 (rank : 35)
Query Neighborhood Hits	222	Target Neighborhood Hits	922	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

OGFR_HUMAN
NC score	0.050317 (rank : 73)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	222	Target Neighborhood Hits	1582	Shared Neighborhood Hits	109
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CABIN_HUMAN
NC score	0.048979 (rank : 74)	θ value	0.0431538 (rank : 47)
Query Neighborhood Hits	222	Target Neighborhood Hits	490	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

GSCR1_HUMAN
NC score	0.048729 (rank : 75)	θ value	0.0113563 (rank : 34)
Query Neighborhood Hits	222	Target Neighborhood Hits	674	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

BCL9_HUMAN
NC score	0.047490 (rank : 76)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	222	Target Neighborhood Hits	1008	Shared Neighborhood Hits	84
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

RPGF4_MOUSE
NC score	0.046732 (rank : 77)	θ value	2.36792 (rank : 130)
Query Neighborhood Hits	222	Target Neighborhood Hits	80	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

SC24C_HUMAN
NC score	0.046685 (rank : 78)	θ value	0.163984 (rank : 58)
Query Neighborhood Hits	222	Target Neighborhood Hits	662	Shared Neighborhood Hits	74
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

KCNQ2_HUMAN
NC score	0.045700 (rank : 79)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	222	Target Neighborhood Hits	114	Shared Neighborhood Hits	45
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
NC score	0.045579 (rank : 80)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	222	Target Neighborhood Hits	163	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

RPGF4_HUMAN
NC score	0.042961 (rank : 81)	θ value	2.36792 (rank : 129)
Query Neighborhood Hits	222	Target Neighborhood Hits	88	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

BAT2_HUMAN
NC score	0.040380 (rank : 82)	θ value	0.813845 (rank : 81)
Query Neighborhood Hits	222	Target Neighborhood Hits	931	Shared Neighborhood Hits	74
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCL9_MOUSE
NC score	0.040357 (rank : 83)	θ value	1.81305 (rank : 112)
Query Neighborhood Hits	222	Target Neighborhood Hits	770	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BAT2_MOUSE
NC score	0.039743 (rank : 84)	θ value	0.21417 (rank : 59)
Query Neighborhood Hits	222	Target Neighborhood Hits	947	Shared Neighborhood Hits	64
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PHLB1_MOUSE
NC score	0.039067 (rank : 85)	θ value	0.0330416 (rank : 44)
Query Neighborhood Hits	222	Target Neighborhood Hits	678	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SRRM2_MOUSE
NC score	0.038596 (rank : 86)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	222	Target Neighborhood Hits	1470	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PHLB1_HUMAN
NC score	0.037302 (rank : 87)	θ value	0.0193708 (rank : 41)
Query Neighborhood Hits	222	Target Neighborhood Hits	1038	Shared Neighborhood Hits	48
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PRP2_MOUSE
NC score	0.036932 (rank : 88)	θ value	0.163984 (rank : 57)
Query Neighborhood Hits	222	Target Neighborhood Hits	347	Shared Neighborhood Hits	38
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

BSN_HUMAN
NC score	0.036337 (rank : 89)	θ value	0.0961366 (rank : 52)
Query Neighborhood Hits	222	Target Neighborhood Hits	1537	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

GP178_HUMAN
NC score	0.036090 (rank : 90)	θ value	0.21417 (rank : 60)
Query Neighborhood Hits	222	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2C4, Q5VTU1	Gene names	GPR178, KIAA1423
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR178.

MDC1_MOUSE
NC score	0.035149 (rank : 91)	θ value	3.0926 (rank : 142)
Query Neighborhood Hits	222	Target Neighborhood Hits	998	Shared Neighborhood Hits	75
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

KCNN4_HUMAN
NC score	0.034054 (rank : 92)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	222	Target Neighborhood Hits	90	Shared Neighborhood Hits	41
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

MISS_MOUSE
NC score	0.033253 (rank : 93)	θ value	5.27518 (rank : 183)
Query Neighborhood Hits	222	Target Neighborhood Hits	444	Shared Neighborhood Hits	51
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

PI5PA_HUMAN
NC score	0.032992 (rank : 94)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	222	Target Neighborhood Hits	749	Shared Neighborhood Hits	66
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

KCNB2_HUMAN
NC score	0.031826 (rank : 95)	θ value	0.813845 (rank : 84)
Query Neighborhood Hits	222	Target Neighborhood Hits	212	Shared Neighborhood Hits	42
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNB1_HUMAN
NC score	0.030353 (rank : 96)	θ value	1.38821 (rank : 101)
Query Neighborhood Hits	222	Target Neighborhood Hits	169	Shared Neighborhood Hits	38
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
NC score	0.030231 (rank : 97)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	222	Target Neighborhood Hits	154	Shared Neighborhood Hits	37
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNF1_HUMAN
NC score	0.029639 (rank : 98)	θ value	3.0926 (rank : 140)
Query Neighborhood Hits	222	Target Neighborhood Hits	109	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

TTP_HUMAN
NC score	0.029578 (rank : 99)	θ value	0.0431538 (rank : 48)
Query Neighborhood Hits	222	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

PCLO_HUMAN
NC score	0.028751 (rank : 100)	θ value	0.0113563 (rank : 36)
Query Neighborhood Hits	222	Target Neighborhood Hits	2046	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CK036_HUMAN
NC score	0.028649 (rank : 101)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	222	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q2M3A8, Q6TF48, Q8N7R8, Q8N9X7	Gene names	C11orf36
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf36.

WBP11_MOUSE
NC score	0.027336 (rank : 102)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	222	Target Neighborhood Hits	362	Shared Neighborhood Hits	42
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

ATN1_HUMAN
NC score	0.027328 (rank : 103)	θ value	2.36792 (rank : 123)
Query Neighborhood Hits	222	Target Neighborhood Hits	676	Shared Neighborhood Hits	53
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

TENS1_HUMAN
NC score	0.026718 (rank : 104)	θ value	0.0330416 (rank : 45)
Query Neighborhood Hits	222	Target Neighborhood Hits	400	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

S23IP_MOUSE
NC score	0.026275 (rank : 105)	θ value	1.06291 (rank : 92)
Query Neighborhood Hits	222	Target Neighborhood Hits	363	Shared Neighborhood Hits	31
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

RPGF3_HUMAN
NC score	0.025947 (rank : 106)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	222	Target Neighborhood Hits	56	Shared Neighborhood Hits	18
SwissProt Accessions	O95398, O95634, Q8WVN0	Gene names	RAPGEF3, CGEF1, EPAC, EPAC1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).

MAP1A_HUMAN
NC score	0.025641 (rank : 107)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	222	Target Neighborhood Hits	1626	Shared Neighborhood Hits	73
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

IF4G1_MOUSE
NC score	0.025414 (rank : 108)	θ value	0.813845 (rank : 83)
Query Neighborhood Hits	222	Target Neighborhood Hits	534	Shared Neighborhood Hits	46
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

SFRS8_HUMAN
NC score	0.025161 (rank : 109)	θ value	0.365318 (rank : 71)
Query Neighborhood Hits	222	Target Neighborhood Hits	166	Shared Neighborhood Hits	7
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

CG026_HUMAN
NC score	0.024921 (rank : 110)	θ value	1.06291 (rank : 86)
Query Neighborhood Hits	222	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q96N11, Q9BQ43	Gene names	C7orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C7orf26.

WBP11_HUMAN
NC score	0.024896 (rank : 111)	θ value	4.03905 (rank : 169)
Query Neighborhood Hits	222	Target Neighborhood Hits	354	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

ZN207_HUMAN
NC score	0.024807 (rank : 112)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	222	Target Neighborhood Hits	326	Shared Neighborhood Hits	23
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

MLL2_HUMAN
NC score	0.024545 (rank : 113)	θ value	0.21417 (rank : 62)
Query Neighborhood Hits	222	Target Neighborhood Hits	1788	Shared Neighborhood Hits	87
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CS007_MOUSE
NC score	0.024375 (rank : 114)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	222	Target Neighborhood Hits	464	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

PELP1_MOUSE
NC score	0.024307 (rank : 115)	θ value	1.06291 (rank : 90)
Query Neighborhood Hits	222	Target Neighborhood Hits	709	Shared Neighborhood Hits	59
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

K0773_HUMAN
NC score	0.024088 (rank : 116)	θ value	0.21417 (rank : 61)
Query Neighborhood Hits	222	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q86XD5, Q7L0D6, Q86T97	Gene names	KIAA0773
Domain Architecture	No domain graphic available
Description	Uncharacterized protein KIAA0773.

CG026_MOUSE
NC score	0.023444 (rank : 117)	θ value	1.81305 (rank : 113)
Query Neighborhood Hits	222	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGA7, Q3T9D0, Q8BN55	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C7orf26 homolog.

HEMGN_HUMAN
NC score	0.023421 (rank : 118)	θ value	0.47712 (rank : 72)
Query Neighborhood Hits	222	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BXL5, Q6XAR3, Q86XY5, Q9NPC0	Gene names	HEMGN, EDAG, NDR
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (Erythroid differentiation-associated gene protein) (EDAG-1).

K1802_MOUSE
NC score	0.023318 (rank : 119)	θ value	6.88961 (rank : 197)
Query Neighborhood Hits	222	Target Neighborhood Hits	1596	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

YLPM1_HUMAN
NC score	0.023003 (rank : 120)	θ value	2.36792 (rank : 133)
Query Neighborhood Hits	222	Target Neighborhood Hits	670	Shared Neighborhood Hits	42
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

FOXN1_HUMAN
NC score	0.022473 (rank : 121)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	222	Target Neighborhood Hits	377	Shared Neighborhood Hits	34
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

PI5PA_MOUSE
NC score	0.021675 (rank : 122)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	222	Target Neighborhood Hits	331	Shared Neighborhood Hits	26
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

ARI1B_HUMAN
NC score	0.021577 (rank : 123)	θ value	0.813845 (rank : 80)
Query Neighborhood Hits	222	Target Neighborhood Hits	567	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

SHAN2_HUMAN
NC score	0.021163 (rank : 124)	θ value	0.47712 (rank : 73)
Query Neighborhood Hits	222	Target Neighborhood Hits	346	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

CRTC1_HUMAN
NC score	0.021128 (rank : 125)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	222	Target Neighborhood Hits	319	Shared Neighborhood Hits	43
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

LBXCO_HUMAN
NC score	0.020342 (rank : 126)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	222	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

RERE_HUMAN
NC score	0.020138 (rank : 127)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	222	Target Neighborhood Hits	779	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

KCNG3_MOUSE
NC score	0.020136 (rank : 128)	θ value	5.27518 (rank : 179)
Query Neighborhood Hits	222	Target Neighborhood Hits	91	Shared Neighborhood Hits	23
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

PRP1_HUMAN
NC score	0.020019 (rank : 129)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	222	Target Neighborhood Hits	385	Shared Neighborhood Hits	37
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

FBSH_HUMAN
NC score	0.019124 (rank : 130)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	222	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HAH7, Q96CI9, Q9H9X4	Gene names	FBS1, FBS
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

MYCD_MOUSE
NC score	0.018864 (rank : 131)	θ value	1.06291 (rank : 89)
Query Neighborhood Hits	222	Target Neighborhood Hits	144	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

RUSC2_MOUSE
NC score	0.018001 (rank : 132)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	222	Target Neighborhood Hits	305	Shared Neighborhood Hits	30
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

CBP_HUMAN
NC score	0.017275 (rank : 133)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	222	Target Neighborhood Hits	941	Shared Neighborhood Hits	63
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

FA5_HUMAN
NC score	0.016906 (rank : 134)	θ value	0.0961366 (rank : 53)
Query Neighborhood Hits	222	Target Neighborhood Hits	172	Shared Neighborhood Hits	13
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

XRCC1_HUMAN
NC score	0.016615 (rank : 135)	θ value	1.06291 (rank : 93)
Query Neighborhood Hits	222	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	P18887, Q9HCB1	Gene names	XRCC1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

GRIN2_HUMAN
NC score	0.016566 (rank : 136)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	222	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	O60269, Q5SVF0	Gene names	GPRIN2, KIAA0514
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 2 (GRIN2).

K1802_HUMAN
NC score	0.016498 (rank : 137)	θ value	1.06291 (rank : 87)
Query Neighborhood Hits	222	Target Neighborhood Hits	1378	Shared Neighborhood Hits	71
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ASPP1_MOUSE
NC score	0.016349 (rank : 138)	θ value	0.0961366 (rank : 51)
Query Neighborhood Hits	222	Target Neighborhood Hits	1244	Shared Neighborhood Hits	62
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

SFR15_HUMAN
NC score	0.015210 (rank : 139)	θ value	3.0926 (rank : 146)
Query Neighborhood Hits	222	Target Neighborhood Hits	368	Shared Neighborhood Hits	27
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

CMTA2_HUMAN
NC score	0.014790 (rank : 140)	θ value	0.813845 (rank : 82)
Query Neighborhood Hits	222	Target Neighborhood Hits	199	Shared Neighborhood Hits	9
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CJ012_HUMAN
NC score	0.014671 (rank : 141)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	222	Target Neighborhood Hits	467	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

LBXCO_MOUSE
NC score	0.014437 (rank : 142)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	222	Target Neighborhood Hits	140	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BX46, Q3UYA4, Q5W8I2, Q8C0T2	Gene names	Lbxcor1, Corl1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1 (Transcriptional corepressor Corl1).

WASF2_MOUSE
NC score	0.014134 (rank : 143)	θ value	4.03905 (rank : 168)
Query Neighborhood Hits	222	Target Neighborhood Hits	315	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

MLL4_HUMAN
NC score	0.013948 (rank : 144)	θ value	5.27518 (rank : 184)
Query Neighborhood Hits	222	Target Neighborhood Hits	722	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

EP400_MOUSE
NC score	0.013888 (rank : 145)	θ value	1.38821 (rank : 99)
Query Neighborhood Hits	222	Target Neighborhood Hits	592	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

VINC_HUMAN
NC score	0.013494 (rank : 146)	θ value	5.27518 (rank : 194)
Query Neighborhood Hits	222	Target Neighborhood Hits	145	Shared Neighborhood Hits	6
SwissProt Accessions	P18206, Q16450, Q5SWX2, Q7Z3B8, Q8IXU7	Gene names	VCL
Domain Architecture
Description	Vinculin (Metavinculin).

HES6_HUMAN
NC score	0.012947 (rank : 147)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	222	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q96HZ4, Q8N2J2, Q96T93, Q9P2S3	Gene names	HES6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1).

WASF4_HUMAN
NC score	0.012934 (rank : 148)	θ value	8.99809 (rank : 221)
Query Neighborhood Hits	222	Target Neighborhood Hits	282	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

CSKI1_MOUSE
NC score	0.012796 (rank : 149)	θ value	2.36792 (rank : 124)
Query Neighborhood Hits	222	Target Neighborhood Hits	1031	Shared Neighborhood Hits	76
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

EP400_HUMAN
NC score	0.012676 (rank : 150)	θ value	3.0926 (rank : 136)
Query Neighborhood Hits	222	Target Neighborhood Hits	556	Shared Neighborhood Hits	35
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

MUCDL_MOUSE
NC score	0.012660 (rank : 151)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	222	Target Neighborhood Hits	461	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

SF3B4_HUMAN
NC score	0.012419 (rank : 152)	θ value	1.38821 (rank : 110)
Query Neighborhood Hits	222	Target Neighborhood Hits	445	Shared Neighborhood Hits	29
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

VINC_MOUSE
NC score	0.011991 (rank : 153)	θ value	5.27518 (rank : 195)
Query Neighborhood Hits	222	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	Q64727, Q8BP32, Q8BS46, Q922C5, Q922D9	Gene names	Vcl
Domain Architecture
Description	Vinculin (Metavinculin).

WHRN_MOUSE
NC score	0.011783 (rank : 154)	θ value	0.813845 (rank : 85)
Query Neighborhood Hits	222	Target Neighborhood Hits	412	Shared Neighborhood Hits	25
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

SHAN2_MOUSE
NC score	0.011732 (rank : 155)	θ value	8.99809 (rank : 218)
Query Neighborhood Hits	222	Target Neighborhood Hits	446	Shared Neighborhood Hits	17
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

GLYG2_HUMAN
NC score	0.011453 (rank : 156)	θ value	3.0926 (rank : 137)
Query Neighborhood Hits	222	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	O15488, O15485, O15486, O15487, O15489, O15490	Gene names	GYG2
Domain Architecture
Description	Glycogenin-2 (EC 2.4.1.186) (GN-2) (GN2).

SAM14_HUMAN
NC score	0.011252 (rank : 157)	θ value	5.27518 (rank : 189)
Query Neighborhood Hits	222	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

CO3A1_MOUSE
NC score	0.011232 (rank : 158)	θ value	4.03905 (rank : 149)
Query Neighborhood Hits	222	Target Neighborhood Hits	466	Shared Neighborhood Hits	33
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

GON4L_HUMAN
NC score	0.010527 (rank : 159)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	222	Target Neighborhood Hits	555	Shared Neighborhood Hits	25
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

ZC3H6_HUMAN
NC score	0.010391 (rank : 160)	θ value	6.88961 (rank : 201)
Query Neighborhood Hits	222	Target Neighborhood Hits	228	Shared Neighborhood Hits	20
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

3BHS7_MOUSE
NC score	0.010340 (rank : 161)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	222	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQC1	Gene names	Hsd3b7
Domain Architecture
Description	3 beta-hydroxysteroid dehydrogenase type 7 (3 beta-hydroxysteroid dehydrogenase type VII) (3Beta-HSD VII) (3-beta-hydroxy-delta(5)-C27 steroid oxidoreductase) (EC 1.1.1.-) (C(27) 3beta-HSD).

PER1_HUMAN
NC score	0.010340 (rank : 162)	θ value	1.38821 (rank : 108)
Query Neighborhood Hits	222	Target Neighborhood Hits	215	Shared Neighborhood Hits	16
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

GNAS1_HUMAN
NC score	0.010313 (rank : 163)	θ value	4.03905 (rank : 155)
Query Neighborhood Hits	222	Target Neighborhood Hits	278	Shared Neighborhood Hits	26
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

CSKI1_HUMAN
NC score	0.010133 (rank : 164)	θ value	4.03905 (rank : 152)
Query Neighborhood Hits	222	Target Neighborhood Hits	997	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

LR37B_HUMAN
NC score	0.009867 (rank : 165)	θ value	1.06291 (rank : 88)
Query Neighborhood Hits	222	Target Neighborhood Hits	392	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

COAA1_HUMAN
NC score	0.009769 (rank : 166)	θ value	1.38821 (rank : 95)
Query Neighborhood Hits	222	Target Neighborhood Hits	316	Shared Neighborhood Hits	27
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

RASF7_HUMAN
NC score	0.009451 (rank : 167)	θ value	5.27518 (rank : 188)
Query Neighborhood Hits	222	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q02833	Gene names	RASSF7, C11orf13, HRC1
Domain Architecture
Description	Ras association domain-containing protein 7 (HRAS1-related cluster protein 1).

CO2A1_HUMAN
NC score	0.009276 (rank : 168)	θ value	3.0926 (rank : 134)
Query Neighborhood Hits	222	Target Neighborhood Hits	486	Shared Neighborhood Hits	39
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CNOT3_HUMAN
NC score	0.008877 (rank : 169)	θ value	6.88961 (rank : 196)
Query Neighborhood Hits	222	Target Neighborhood Hits	425	Shared Neighborhood Hits	22
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

UBP10_HUMAN
NC score	0.008753 (rank : 170)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	222	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

CO4A2_MOUSE
NC score	0.008717 (rank : 171)	θ value	3.0926 (rank : 135)
Query Neighborhood Hits	222	Target Neighborhood Hits	492	Shared Neighborhood Hits	40
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

WNK2_HUMAN
NC score	0.008556 (rank : 172)	θ value	2.36792 (rank : 132)
Query Neighborhood Hits	222	Target Neighborhood Hits	1407	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

CO4A1_MOUSE
NC score	0.008269 (rank : 173)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	222	Target Neighborhood Hits	450	Shared Neighborhood Hits	40
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

RPGF6_HUMAN
NC score	0.008082 (rank : 174)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	222	Target Neighborhood Hits	266	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

TEX14_HUMAN
NC score	0.008048 (rank : 175)	θ value	5.27518 (rank : 193)
Query Neighborhood Hits	222	Target Neighborhood Hits	1103	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

AMOL2_MOUSE
NC score	0.007942 (rank : 176)	θ value	0.813845 (rank : 79)
Query Neighborhood Hits	222	Target Neighborhood Hits	591	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

SYN2_MOUSE
NC score	0.007840 (rank : 177)	θ value	5.27518 (rank : 192)
Query Neighborhood Hits	222	Target Neighborhood Hits	183	Shared Neighborhood Hits	20
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

PO2F2_HUMAN
NC score	0.007704 (rank : 178)	θ value	1.38821 (rank : 109)
Query Neighborhood Hits	222	Target Neighborhood Hits	379	Shared Neighborhood Hits	17
SwissProt Accessions	P09086, Q16648, Q9BRS4	Gene names	POU2F2, OCT2, OTF2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

MAST2_MOUSE
NC score	0.007613 (rank : 179)	θ value	0.0330416 (rank : 43)
Query Neighborhood Hits	222	Target Neighborhood Hits	1110	Shared Neighborhood Hits	34
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

FOXN4_HUMAN
NC score	0.007436 (rank : 180)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	222	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

TFE2_HUMAN
NC score	0.007350 (rank : 181)	θ value	6.88961 (rank : 200)
Query Neighborhood Hits	222	Target Neighborhood Hits	161	Shared Neighborhood Hits	14
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

PANK1_HUMAN
NC score	0.007349 (rank : 182)	θ value	5.27518 (rank : 185)
Query Neighborhood Hits	222	Target Neighborhood Hits	75	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TE04, Q7RTX6, Q7Z495, Q8TBQ8	Gene names	PANK1, PANK
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (hPanK1) (hPanK).

CONA1_HUMAN
NC score	0.007296 (rank : 183)	θ value	4.03905 (rank : 150)
Query Neighborhood Hits	222	Target Neighborhood Hits	281	Shared Neighborhood Hits	21
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

B3A3_HUMAN
NC score	0.007064 (rank : 184)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	222	Target Neighborhood Hits	119	Shared Neighborhood Hits	15
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

WNK4_MOUSE
NC score	0.007062 (rank : 185)	θ value	0.279714 (rank : 66)
Query Neighborhood Hits	222	Target Neighborhood Hits	961	Shared Neighborhood Hits	35
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

GP152_MOUSE
NC score	0.007015 (rank : 186)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	222	Target Neighborhood Hits	607	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

TESK1_HUMAN
NC score	0.006977 (rank : 187)	θ value	0.0330416 (rank : 46)
Query Neighborhood Hits	222	Target Neighborhood Hits	864	Shared Neighborhood Hits	22
SwissProt Accessions	Q15569	Gene names	TESK1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

SMCA4_HUMAN
NC score	0.006762 (rank : 188)	θ value	5.27518 (rank : 190)
Query Neighborhood Hits	222	Target Neighborhood Hits	597	Shared Neighborhood Hits	34
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

DYN3_HUMAN
NC score	0.006760 (rank : 189)	θ value	4.03905 (rank : 153)
Query Neighborhood Hits	222	Target Neighborhood Hits	158	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

SRBP1_HUMAN
NC score	0.006511 (rank : 190)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	222	Target Neighborhood Hits	225	Shared Neighborhood Hits	19
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

PO2F2_MOUSE
NC score	0.006500 (rank : 191)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	222	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	Q00196, Q00197, Q00198, Q00199, Q00200, Q00201, Q05882, Q61995, Q61996, Q64245	Gene names	Pou2f2, Oct2, Otf2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

MBRL_MOUSE
NC score	0.006397 (rank : 192)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	222	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIV2, Q68EE1, Q6KAN7, Q7TS84, Q8CIV1, Q99K29	Gene names	ORF61
Domain Architecture	No domain graphic available
Description	Membralin.

CSTFT_MOUSE
NC score	0.006320 (rank : 193)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	222	Target Neighborhood Hits	356	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C7E9, Q6A016, Q8BHH7, Q8C3W7, Q8R2Y1, Q9EPU3	Gene names	Cstf2t, Kiaa0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

SALL2_MOUSE
NC score	0.006058 (rank : 194)	θ value	0.0563607 (rank : 50)
Query Neighborhood Hits	222	Target Neighborhood Hits	836	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QX96	Gene names	Sall2, Sal2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Spalt-like protein 2) (MSal-2).

MAGC1_HUMAN
NC score	0.006043 (rank : 195)	θ value	5.27518 (rank : 181)
Query Neighborhood Hits	222	Target Neighborhood Hits	431	Shared Neighborhood Hits	24
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

COEA1_MOUSE
NC score	0.005598 (rank : 196)	θ value	1.38821 (rank : 96)
Query Neighborhood Hits	222	Target Neighborhood Hits	402	Shared Neighborhood Hits	20
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

TESK1_MOUSE
NC score	0.005568 (rank : 197)	θ value	0.47712 (rank : 74)
Query Neighborhood Hits	222	Target Neighborhood Hits	862	Shared Neighborhood Hits	20
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

PTC1_HUMAN
NC score	0.005373 (rank : 198)	θ value	5.27518 (rank : 187)
Query Neighborhood Hits	222	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q13635, Q13463, Q5VZC0	Gene names	PTCH1, PTCH
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

DMD_HUMAN
NC score	0.005131 (rank : 199)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	222	Target Neighborhood Hits	1135	Shared Neighborhood Hits	19
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

RAVR1_MOUSE
NC score	0.004920 (rank : 200)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	222	Target Neighborhood Hits	179	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CW46, Q5DTT6, Q811K0, Q8C3Z1, Q8CA14	Gene names	Raver1, Kiaa1978
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 1 (Protein raver-1).

ST5_HUMAN
NC score	0.004785 (rank : 201)	θ value	5.27518 (rank : 191)
Query Neighborhood Hits	222	Target Neighborhood Hits	151	Shared Neighborhood Hits	9
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

DMD_MOUSE
NC score	0.004688 (rank : 202)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	222	Target Neighborhood Hits	1111	Shared Neighborhood Hits	17
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

TNIK_HUMAN
NC score	0.004525 (rank : 203)	θ value	0.21417 (rank : 63)
Query Neighborhood Hits	222	Target Neighborhood Hits	1570	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

ACK1_MOUSE
NC score	0.004505 (rank : 204)	θ value	0.279714 (rank : 64)
Query Neighborhood Hits	222	Target Neighborhood Hits	1080	Shared Neighborhood Hits	41
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

PAK4_MOUSE
NC score	0.004472 (rank : 205)	θ value	6.88961 (rank : 199)
Query Neighborhood Hits	222	Target Neighborhood Hits	1098	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

FXL16_HUMAN
NC score	0.003989 (rank : 206)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	222	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

LPIN3_MOUSE
NC score	0.003600 (rank : 207)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	222	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PI4, Q3TQ75, Q8C7R9	Gene names	Lpin3
Domain Architecture
Description	Lipin-3.

RXRB_HUMAN
NC score	0.003523 (rank : 208)	θ value	2.36792 (rank : 131)
Query Neighborhood Hits	222	Target Neighborhood Hits	280	Shared Neighborhood Hits	21
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

MRCKG_HUMAN
NC score	0.003385 (rank : 209)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	222	Target Neighborhood Hits	1519	Shared Neighborhood Hits	28
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

CLIC6_MOUSE
NC score	0.003258 (rank : 210)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	222	Target Neighborhood Hits	134	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BHB9	Gene names	Clic6
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

MGR5_HUMAN
NC score	0.002824 (rank : 211)	θ value	5.27518 (rank : 182)
Query Neighborhood Hits	222	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

ZEP2_HUMAN
NC score	0.002316 (rank : 212)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	222	Target Neighborhood Hits	937	Shared Neighborhood Hits	29
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

HUNK_HUMAN
NC score	0.002291 (rank : 213)	θ value	3.0926 (rank : 138)
Query Neighborhood Hits	222	Target Neighborhood Hits	884	Shared Neighborhood Hits	18
SwissProt Accessions	P57058	Gene names	HUNK, MAKV
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V) (B19).

ATS14_HUMAN
NC score	0.002239 (rank : 214)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	222	Target Neighborhood Hits	382	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

DYNA_HUMAN
NC score	0.001973 (rank : 215)	θ value	4.03905 (rank : 154)
Query Neighborhood Hits	222	Target Neighborhood Hits	1194	Shared Neighborhood Hits	24
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

ZN687_MOUSE
NC score	0.001758 (rank : 216)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	222	Target Neighborhood Hits	913	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

COT1_MOUSE
NC score	0.001753 (rank : 217)	θ value	4.03905 (rank : 151)
Query Neighborhood Hits	222	Target Neighborhood Hits	160	Shared Neighborhood Hits	8
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

ZEP2_MOUSE
NC score	0.001424 (rank : 218)	θ value	6.88961 (rank : 202)
Query Neighborhood Hits	222	Target Neighborhood Hits	964	Shared Neighborhood Hits	31
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

HXC4_HUMAN
NC score	0.001210 (rank : 219)	θ value	3.0926 (rank : 139)
Query Neighborhood Hits	222	Target Neighborhood Hits	361	Shared Neighborhood Hits	8
SwissProt Accessions	P09017	Gene names	HOXC4, HOX3E
Domain Architecture
Description	Homeobox protein Hox-C4 (Hox-3E) (CP19).

PRDM2_HUMAN
NC score	0.001203 (rank : 220)	θ value	5.27518 (rank : 186)
Query Neighborhood Hits	222	Target Neighborhood Hits	1135	Shared Neighborhood Hits	37
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

HXC4_MOUSE
NC score	0.001067 (rank : 221)	θ value	4.03905 (rank : 156)
Query Neighborhood Hits	222	Target Neighborhood Hits	365	Shared Neighborhood Hits	9
SwissProt Accessions	Q08624	Gene names	Hoxc4, Hox-3.5, Hoxc-4
Domain Architecture
Description	Homeobox protein Hox-C4 (Hox-3.5).

GLI1_HUMAN
NC score	0.000875 (rank : 222)	θ value	0.163984 (rank : 54)
Query Neighborhood Hits	222	Target Neighborhood Hits	828	Shared Neighborhood Hits	22
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

TRIO_HUMAN
NC score	0.000770 (rank : 223)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	222	Target Neighborhood Hits	1580	Shared Neighborhood Hits	32
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

CSPG3_HUMAN
NC score	0.000647 (rank : 224)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	222	Target Neighborhood Hits	676	Shared Neighborhood Hits	21
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LHX1_MOUSE
NC score	0.000416 (rank : 225)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	222	Target Neighborhood Hits	453	Shared Neighborhood Hits	7
SwissProt Accessions	P63006, P36199	Gene names	Lhx1, Lim-1, Lim1
Domain Architecture	No domain graphic available
Description	LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1).

ZN438_HUMAN
NC score	0.000162 (rank : 226)	θ value	8.99809 (rank : 222)
Query Neighborhood Hits	222	Target Neighborhood Hits	906	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

ZN295_HUMAN
NC score	-0.000379 (rank : 227)	θ value	1.38821 (rank : 111)
Query Neighborhood Hits	222	Target Neighborhood Hits	847	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULJ3, Q6P4R0	Gene names	ZNF295, KIAA1227, ZBTB21
Domain Architecture
Description	Zinc finger protein 295 (Zinc finger and BTB domain-containing protein 21).

DRD4_HUMAN
NC score	-0.002279 (rank : 228)	θ value	2.36792 (rank : 125)
Query Neighborhood Hits	222	Target Neighborhood Hits	886	Shared Neighborhood Hits	8
SwissProt Accessions	P21917	Gene names	DRD4
Domain Architecture
Description	D(4) dopamine receptor (Dopamine D4 receptor) (D(2C) dopamine receptor).

KLF3_MOUSE
NC score	-0.003086 (rank : 229)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	222	Target Neighborhood Hits	715	Shared Neighborhood Hits	13
SwissProt Accessions	Q60980	Gene names	Klf3, Bklf
Domain Architecture
Description	Krueppel-like factor 3 (Basic krueppel-like factor) (CACCC-box-binding protein BKLF) (TEF-2).