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Network neighborhood for query Sequence : KCNH5_MOUSE

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KCNH5_MOUSE
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KCNH1_HUMAN
θ value	0 (rank : 1)	NC score	0.996498 (rank : 4)
Query Neighborhood Hits	102	Target Neighborhood Hits	98	Shared Neighborhood Hits	71
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH1_MOUSE
θ value	0 (rank : 2)	NC score	0.996585 (rank : 3)
Query Neighborhood Hits	102	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH5_HUMAN
θ value	0 (rank : 3)	NC score	0.998931 (rank : 2)
Query Neighborhood Hits	102	Target Neighborhood Hits	99	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH5_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	102	Target Neighborhood Hits	102	Shared Neighborhood Hits	102
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH8_HUMAN
θ value	1.28961e-139 (rank : 5)	NC score	0.968588 (rank : 5)
Query Neighborhood Hits	102	Target Neighborhood Hits	104	Shared Neighborhood Hits	60
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH6_HUMAN
θ value	1.02182e-136 (rank : 6)	NC score	0.960894 (rank : 9)
Query Neighborhood Hits	102	Target Neighborhood Hits	222	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH3_HUMAN
θ value	2.35568e-133 (rank : 7)	NC score	0.961581 (rank : 7)
Query Neighborhood Hits	102	Target Neighborhood Hits	148	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
θ value	5.24793e-133 (rank : 8)	NC score	0.961543 (rank : 8)
Query Neighborhood Hits	102	Target Neighborhood Hits	133	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH4_HUMAN
θ value	4.15819e-130 (rank : 9)	NC score	0.964338 (rank : 6)
Query Neighborhood Hits	102	Target Neighborhood Hits	177	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH2_HUMAN
θ value	7.10925e-122 (rank : 10)	NC score	0.954225 (rank : 10)
Query Neighborhood Hits	102	Target Neighborhood Hits	158	Shared Neighborhood Hits	57
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
θ value	7.10925e-122 (rank : 11)	NC score	0.954017 (rank : 11)
Query Neighborhood Hits	102	Target Neighborhood Hits	165	Shared Neighborhood Hits	57
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_MOUSE
θ value	2.00348e-116 (rank : 12)	NC score	0.953140 (rank : 12)
Query Neighborhood Hits	102	Target Neighborhood Hits	98	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH7_HUMAN
θ value	2.70778e-113 (rank : 13)	NC score	0.951989 (rank : 13)
Query Neighborhood Hits	102	Target Neighborhood Hits	107	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

HCN1_MOUSE
θ value	2.19075e-38 (rank : 14)	NC score	0.795665 (rank : 19)
Query Neighborhood Hits	102	Target Neighborhood Hits	172	Shared Neighborhood Hits	35
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN1_HUMAN
θ value	4.88048e-38 (rank : 15)	NC score	0.799174 (rank : 16)
Query Neighborhood Hits	102	Target Neighborhood Hits	120	Shared Neighborhood Hits	34
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN2_MOUSE
θ value	2.05049e-36 (rank : 16)	NC score	0.780189 (rank : 23)
Query Neighborhood Hits	102	Target Neighborhood Hits	278	Shared Neighborhood Hits	34
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_HUMAN
θ value	5.96599e-36 (rank : 17)	NC score	0.777599 (rank : 24)
Query Neighborhood Hits	102	Target Neighborhood Hits	303	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
θ value	1.32909e-35 (rank : 18)	NC score	0.775823 (rank : 25)
Query Neighborhood Hits	102	Target Neighborhood Hits	284	Shared Neighborhood Hits	37
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_HUMAN
θ value	1.73584e-35 (rank : 19)	NC score	0.771681 (rank : 26)
Query Neighborhood Hits	102	Target Neighborhood Hits	369	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CNGA2_MOUSE
θ value	2.96089e-35 (rank : 20)	NC score	0.812876 (rank : 14)
Query Neighborhood Hits	102	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

HCN3_HUMAN
θ value	5.584e-34 (rank : 21)	NC score	0.793160 (rank : 20)
Query Neighborhood Hits	102	Target Neighborhood Hits	99	Shared Neighborhood Hits	35
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN3_MOUSE
θ value	1.6247e-33 (rank : 22)	NC score	0.793141 (rank : 22)
Query Neighborhood Hits	102	Target Neighborhood Hits	112	Shared Neighborhood Hits	34
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

CNGA1_HUMAN
θ value	1.16434e-31 (rank : 23)	NC score	0.800763 (rank : 15)
Query Neighborhood Hits	102	Target Neighborhood Hits	149	Shared Neighborhood Hits	36
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
θ value	7.54701e-31 (rank : 24)	NC score	0.796255 (rank : 18)
Query Neighborhood Hits	102	Target Neighborhood Hits	198	Shared Neighborhood Hits	37
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
θ value	2.42779e-29 (rank : 25)	NC score	0.798379 (rank : 17)
Query Neighborhood Hits	102	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
θ value	3.28125e-26 (rank : 26)	NC score	0.793150 (rank : 21)
Query Neighborhood Hits	102	Target Neighborhood Hits	125	Shared Neighborhood Hits	36
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGB3_HUMAN
θ value	2.87452e-22 (rank : 27)	NC score	0.735992 (rank : 28)
Query Neighborhood Hits	102	Target Neighborhood Hits	206	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_MOUSE
θ value	3.51386e-20 (rank : 28)	NC score	0.745779 (rank : 27)
Query Neighborhood Hits	102	Target Neighborhood Hits	74	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB1_HUMAN
θ value	1.33526e-19 (rank : 29)	NC score	0.725491 (rank : 29)
Query Neighborhood Hits	102	Target Neighborhood Hits	222	Shared Neighborhood Hits	35
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNKH_HUMAN
θ value	0.00020696 (rank : 30)	NC score	0.289026 (rank : 30)
Query Neighborhood Hits	102	Target Neighborhood Hits	89	Shared Neighborhood Hits	54
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNK2_HUMAN
θ value	0.00035302 (rank : 31)	NC score	0.225198 (rank : 31)
Query Neighborhood Hits	102	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	0.000602161 (rank : 32)	NC score	0.224215 (rank : 32)
Query Neighborhood Hits	102	Target Neighborhood Hits	88	Shared Neighborhood Hits	51
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_HUMAN
θ value	0.00175202 (rank : 33)	NC score	0.219741 (rank : 34)
Query Neighborhood Hits	102	Target Neighborhood Hits	88	Shared Neighborhood Hits	49
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
θ value	0.00298849 (rank : 34)	NC score	0.215210 (rank : 36)
Query Neighborhood Hits	102	Target Neighborhood Hits	93	Shared Neighborhood Hits	52
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK4_HUMAN
θ value	0.00298849 (rank : 35)	NC score	0.205968 (rank : 39)
Query Neighborhood Hits	102	Target Neighborhood Hits	109	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK6_HUMAN
θ value	0.00298849 (rank : 36)	NC score	0.214853 (rank : 37)
Query Neighborhood Hits	102	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNKA_HUMAN
θ value	0.00509761 (rank : 37)	NC score	0.217727 (rank : 35)
Query Neighborhood Hits	102	Target Neighborhood Hits	111	Shared Neighborhood Hits	54
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNKG_HUMAN
θ value	0.00509761 (rank : 38)	NC score	0.209922 (rank : 38)
Query Neighborhood Hits	102	Target Neighborhood Hits	90	Shared Neighborhood Hits	54
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNK9_HUMAN
θ value	0.0113563 (rank : 39)	NC score	0.191637 (rank : 42)
Query Neighborhood Hits	102	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK9_MOUSE
θ value	0.0113563 (rank : 40)	NC score	0.192051 (rank : 41)
Query Neighborhood Hits	102	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCND3_HUMAN
θ value	0.0193708 (rank : 41)	NC score	0.081011 (rank : 57)
Query Neighborhood Hits	102	Target Neighborhood Hits	162	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	0.0193708 (rank : 42)	NC score	0.081002 (rank : 58)
Query Neighborhood Hits	102	Target Neighborhood Hits	162	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNK4_MOUSE
θ value	0.0252991 (rank : 43)	NC score	0.193814 (rank : 40)
Query Neighborhood Hits	102	Target Neighborhood Hits	118	Shared Neighborhood Hits	49
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCNKF_HUMAN
θ value	0.0252991 (rank : 44)	NC score	0.224154 (rank : 33)
Query Neighborhood Hits	102	Target Neighborhood Hits	87	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCND1_MOUSE
θ value	0.0961366 (rank : 45)	NC score	0.087253 (rank : 54)
Query Neighborhood Hits	102	Target Neighborhood Hits	165	Shared Neighborhood Hits	53
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
θ value	0.125558 (rank : 46)	NC score	0.082408 (rank : 56)
Query Neighborhood Hits	102	Target Neighborhood Hits	160	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND2_HUMAN
θ value	0.125558 (rank : 47)	NC score	0.080929 (rank : 59)
Query Neighborhood Hits	102	Target Neighborhood Hits	154	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	0.125558 (rank : 48)	NC score	0.080928 (rank : 60)
Query Neighborhood Hits	102	Target Neighborhood Hits	156	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCNK1_HUMAN
θ value	0.279714 (rank : 49)	NC score	0.164815 (rank : 43)
Query Neighborhood Hits	102	Target Neighborhood Hits	68	Shared Neighborhood Hits	44
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNK5_HUMAN
θ value	0.279714 (rank : 50)	NC score	0.163699 (rank : 44)
Query Neighborhood Hits	102	Target Neighborhood Hits	102	Shared Neighborhood Hits	53
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KCNK1_MOUSE
θ value	0.365318 (rank : 51)	NC score	0.161173 (rank : 45)
Query Neighborhood Hits	102	Target Neighborhood Hits	70	Shared Neighborhood Hits	43
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KCNKD_MOUSE
θ value	0.47712 (rank : 52)	NC score	0.128288 (rank : 47)
Query Neighborhood Hits	102	Target Neighborhood Hits	51	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

NOLC1_HUMAN
θ value	0.47712 (rank : 53)	NC score	0.015211 (rank : 93)
Query Neighborhood Hits	102	Target Neighborhood Hits	452	Shared Neighborhood Hits	6
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

KGP1B_MOUSE
θ value	0.62314 (rank : 54)	NC score	0.040202 (rank : 79)
Query Neighborhood Hits	102	Target Neighborhood Hits	922	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

DEK_MOUSE
θ value	1.06291 (rank : 55)	NC score	0.020597 (rank : 91)
Query Neighborhood Hits	102	Target Neighborhood Hits	280	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

KCNG4_HUMAN
θ value	1.06291 (rank : 56)	NC score	0.044242 (rank : 73)
Query Neighborhood Hits	102	Target Neighborhood Hits	99	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

DTX3_MOUSE
θ value	1.38821 (rank : 57)	NC score	0.020657 (rank : 90)
Query Neighborhood Hits	102	Target Neighborhood Hits	202	Shared Neighborhood Hits	5
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

FMN1B_MOUSE
θ value	1.38821 (rank : 58)	NC score	0.011860 (rank : 97)
Query Neighborhood Hits	102	Target Neighborhood Hits	447	Shared Neighborhood Hits	8
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

KGP1A_HUMAN
θ value	1.38821 (rank : 59)	NC score	0.040017 (rank : 81)
Query Neighborhood Hits	102	Target Neighborhood Hits	901	Shared Neighborhood Hits	35
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.040055 (rank : 80)
Query Neighborhood Hits	102	Target Neighborhood Hits	921	Shared Neighborhood Hits	35
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

ARMX5_MOUSE
θ value	1.81305 (rank : 61)	NC score	0.014391 (rank : 94)
Query Neighborhood Hits	102	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UZB0	Gene names	Armcx5
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 5.

CLP46_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.013039 (rank : 95)
Query Neighborhood Hits	102	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYB9, Q8R0H7	Gene names	Clp46
Domain Architecture	No domain graphic available
Description	CAP10-like 46 kDa protein precursor.

CUTL1_MOUSE
θ value	1.81305 (rank : 63)	NC score	0.003710 (rank : 109)
Query Neighborhood Hits	102	Target Neighborhood Hits	1620	Shared Neighborhood Hits	16
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

DTX3_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.019588 (rank : 92)
Query Neighborhood Hits	102	Target Neighborhood Hits	198	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

KCNQ4_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.049988 (rank : 72)
Query Neighborhood Hits	102	Target Neighborhood Hits	136	Shared Neighborhood Hits	42
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNQ5_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.037240 (rank : 84)
Query Neighborhood Hits	102	Target Neighborhood Hits	163	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

TSH2_MOUSE
θ value	1.81305 (rank : 67)	NC score	0.009109 (rank : 99)
Query Neighborhood Hits	102	Target Neighborhood Hits	467	Shared Neighborhood Hits	5
SwissProt Accessions	Q68FE9, Q5DTF1, Q6AXH5, Q9JL71	Gene names	Tshz2, Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (SDCCAG33-like protein).

KCNK7_MOUSE
θ value	2.36792 (rank : 68)	NC score	0.109817 (rank : 49)
Query Neighborhood Hits	102	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNKD_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.109200 (rank : 50)
Query Neighborhood Hits	102	Target Neighborhood Hits	58	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNS1_HUMAN
θ value	2.36792 (rank : 70)	NC score	0.036480 (rank : 86)
Query Neighborhood Hits	102	Target Neighborhood Hits	116	Shared Neighborhood Hits	29
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

TRDN_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.010928 (rank : 98)
Query Neighborhood Hits	102	Target Neighborhood Hits	542	Shared Neighborhood Hits	10
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

BPTF_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.006084 (rank : 106)
Query Neighborhood Hits	102	Target Neighborhood Hits	786	Shared Neighborhood Hits	12
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRWD1_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.002423 (rank : 110)
Query Neighborhood Hits	102	Target Neighborhood Hits	448	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

MYH13_HUMAN
θ value	3.0926 (rank : 74)	NC score	-0.000811 (rank : 115)
Query Neighborhood Hits	102	Target Neighborhood Hits	1504	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

AIM1_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.007407 (rank : 105)
Query Neighborhood Hits	102	Target Neighborhood Hits	247	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

CORO6_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.003952 (rank : 108)
Query Neighborhood Hits	102	Target Neighborhood Hits	246	Shared Neighborhood Hits	5
SwissProt Accessions	Q920M5, Q920M3, Q920M4	Gene names	Coro6
Domain Architecture	No domain graphic available
Description	Coronin-6 (Clipin E).

KCNA2_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.038589 (rank : 82)
Query Neighborhood Hits	102	Target Neighborhood Hits	102	Shared Neighborhood Hits	39
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNB1_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.042421 (rank : 76)
Query Neighborhood Hits	102	Target Neighborhood Hits	169	Shared Neighborhood Hits	39
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.042467 (rank : 75)
Query Neighborhood Hits	102	Target Neighborhood Hits	154	Shared Neighborhood Hits	40
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB2_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.043672 (rank : 74)
Query Neighborhood Hits	102	Target Neighborhood Hits	212	Shared Neighborhood Hits	39
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS2_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.051820 (rank : 70)
Query Neighborhood Hits	102	Target Neighborhood Hits	129	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

TFE3_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.008179 (rank : 103)
Query Neighborhood Hits	102	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

APC_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.005591 (rank : 107)
Query Neighborhood Hits	102	Target Neighborhood Hits	441	Shared Neighborhood Hits	7
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

KCNS2_MOUSE
θ value	5.27518 (rank : 84)	NC score	0.051215 (rank : 71)
Query Neighborhood Hits	102	Target Neighborhood Hits	130	Shared Neighborhood Hits	38
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNT1_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.040336 (rank : 78)
Query Neighborhood Hits	102	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	Q5JUK3, Q9P2C5	Gene names	KCNT1, KIAA1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1 (KCa4.1).

KCNG2_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.041704 (rank : 77)
Query Neighborhood Hits	102	Target Neighborhood Hits	83	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNKC_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.104048 (rank : 52)
Query Neighborhood Hits	102	Target Neighborhood Hits	51	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

KCNT1_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.035156 (rank : 87)
Query Neighborhood Hits	102	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZPR4, Q8C3E7	Gene names	Kcnt1, Kiaa1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1.

KGP2_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.029240 (rank : 88)
Query Neighborhood Hits	102	Target Neighborhood Hits	1023	Shared Neighborhood Hits	28
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

PEX14_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.008481 (rank : 102)
Query Neighborhood Hits	102	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R0A0	Gene names	Pex14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

PLCB2_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.002133 (rank : 111)
Query Neighborhood Hits	102	Target Neighborhood Hits	608	Shared Neighborhood Hits	10
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

RAI14_MOUSE
θ value	6.88961 (rank : 92)	NC score	-0.001645 (rank : 116)
Query Neighborhood Hits	102	Target Neighborhood Hits	1505	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

TPR_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.000234 (rank : 114)
Query Neighborhood Hits	102	Target Neighborhood Hits	1921	Shared Neighborhood Hits	24
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRAF6_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.008695 (rank : 101)
Query Neighborhood Hits	102	Target Neighborhood Hits	267	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

DMP1_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.009052 (rank : 100)
Query Neighborhood Hits	102	Target Neighborhood Hits	491	Shared Neighborhood Hits	9
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DSPP_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.001566 (rank : 112)
Query Neighborhood Hits	102	Target Neighborhood Hits	645	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

GCR_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.000286 (rank : 113)
Query Neighborhood Hits	102	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

GON4L_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.007960 (rank : 104)
Query Neighborhood Hits	102	Target Neighborhood Hits	555	Shared Neighborhood Hits	10
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

KCNA2_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.037066 (rank : 85)
Query Neighborhood Hits	102	Target Neighborhood Hits	101	Shared Neighborhood Hits	39
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA4_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.038289 (rank : 83)
Query Neighborhood Hits	102	Target Neighborhood Hits	108	Shared Neighborhood Hits	42
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KGP2_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.028518 (rank : 89)
Query Neighborhood Hits	102	Target Neighborhood Hits	1029	Shared Neighborhood Hits	27
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

SYV_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.012131 (rank : 96)
Query Neighborhood Hits	102	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P26640, Q5JQ90, Q96E77, Q9UQM2	Gene names	VARS, G7A, VARS2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

CT152_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.061683 (rank : 65)
Query Neighborhood Hits	102	Target Neighborhood Hits	38	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KAP0_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.131827 (rank : 46)
Query Neighborhood Hits	102	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP0_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.119747 (rank : 48)
Query Neighborhood Hits	102	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.106360 (rank : 51)
Query Neighborhood Hits	102	Target Neighborhood Hits	58	Shared Neighborhood Hits	26
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.104021 (rank : 53)
Query Neighborhood Hits	102	Target Neighborhood Hits	49	Shared Neighborhood Hits	26
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP2_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.077445 (rank : 63)
Query Neighborhood Hits	102	Target Neighborhood Hits	48	Shared Neighborhood Hits	18
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.079546 (rank : 61)
Query Neighborhood Hits	102	Target Neighborhood Hits	44	Shared Neighborhood Hits	18
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.076107 (rank : 64)
Query Neighborhood Hits	102	Target Neighborhood Hits	40	Shared Neighborhood Hits	21
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.079359 (rank : 62)
Query Neighborhood Hits	102	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KCMA1_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.058362 (rank : 67)
Query Neighborhood Hits	102	Target Neighborhood Hits	96	Shared Neighborhood Hits	43
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCMA1_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.058500 (rank : 66)
Query Neighborhood Hits	102	Target Neighborhood Hits	94	Shared Neighborhood Hits	43
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCNK7_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.086389 (rank : 55)
Query Neighborhood Hits	102	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCNQ3_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.053019 (rank : 69)
Query Neighborhood Hits	102	Target Neighborhood Hits	114	Shared Neighborhood Hits	47
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.054324 (rank : 68)
Query Neighborhood Hits	102	Target Neighborhood Hits	105	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

Hits sorted by NC score

KCNH5_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	102	Target Neighborhood Hits	102	Shared Neighborhood Hits	102
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
NC score	0.998931 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	102	Target Neighborhood Hits	99	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH1_MOUSE
NC score	0.996585 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	102	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.996498 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	102	Target Neighborhood Hits	98	Shared Neighborhood Hits	71
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH8_HUMAN
NC score	0.968588 (rank : 5)	θ value	1.28961e-139 (rank : 5)
Query Neighborhood Hits	102	Target Neighborhood Hits	104	Shared Neighborhood Hits	60
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH4_HUMAN
NC score	0.964338 (rank : 6)	θ value	4.15819e-130 (rank : 9)
Query Neighborhood Hits	102	Target Neighborhood Hits	177	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH3_HUMAN
NC score	0.961581 (rank : 7)	θ value	2.35568e-133 (rank : 7)
Query Neighborhood Hits	102	Target Neighborhood Hits	148	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
NC score	0.961543 (rank : 8)	θ value	5.24793e-133 (rank : 8)
Query Neighborhood Hits	102	Target Neighborhood Hits	133	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH6_HUMAN
NC score	0.960894 (rank : 9)	θ value	1.02182e-136 (rank : 6)
Query Neighborhood Hits	102	Target Neighborhood Hits	222	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_HUMAN
NC score	0.954225 (rank : 10)	θ value	7.10925e-122 (rank : 10)
Query Neighborhood Hits	102	Target Neighborhood Hits	158	Shared Neighborhood Hits	57
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
NC score	0.954017 (rank : 11)	θ value	7.10925e-122 (rank : 11)
Query Neighborhood Hits	102	Target Neighborhood Hits	165	Shared Neighborhood Hits	57
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_MOUSE
NC score	0.953140 (rank : 12)	θ value	2.00348e-116 (rank : 12)
Query Neighborhood Hits	102	Target Neighborhood Hits	98	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH7_HUMAN
NC score	0.951989 (rank : 13)	θ value	2.70778e-113 (rank : 13)
Query Neighborhood Hits	102	Target Neighborhood Hits	107	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

CNGA2_MOUSE
NC score	0.812876 (rank : 14)	θ value	2.96089e-35 (rank : 20)
Query Neighborhood Hits	102	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA1_HUMAN
NC score	0.800763 (rank : 15)	θ value	1.16434e-31 (rank : 23)
Query Neighborhood Hits	102	Target Neighborhood Hits	149	Shared Neighborhood Hits	36
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

HCN1_HUMAN
NC score	0.799174 (rank : 16)	θ value	4.88048e-38 (rank : 15)
Query Neighborhood Hits	102	Target Neighborhood Hits	120	Shared Neighborhood Hits	34
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

CNGA3_MOUSE
NC score	0.798379 (rank : 17)	θ value	2.42779e-29 (rank : 25)
Query Neighborhood Hits	102	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
NC score	0.796255 (rank : 18)	θ value	7.54701e-31 (rank : 24)
Query Neighborhood Hits	102	Target Neighborhood Hits	198	Shared Neighborhood Hits	37
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

HCN1_MOUSE
NC score	0.795665 (rank : 19)	θ value	2.19075e-38 (rank : 14)
Query Neighborhood Hits	102	Target Neighborhood Hits	172	Shared Neighborhood Hits	35
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN3_HUMAN
NC score	0.793160 (rank : 20)	θ value	5.584e-34 (rank : 21)
Query Neighborhood Hits	102	Target Neighborhood Hits	99	Shared Neighborhood Hits	35
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

CNGA3_HUMAN
NC score	0.793150 (rank : 21)	θ value	3.28125e-26 (rank : 26)
Query Neighborhood Hits	102	Target Neighborhood Hits	125	Shared Neighborhood Hits	36
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

HCN3_MOUSE
NC score	0.793141 (rank : 22)	θ value	1.6247e-33 (rank : 22)
Query Neighborhood Hits	102	Target Neighborhood Hits	112	Shared Neighborhood Hits	34
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN2_MOUSE
NC score	0.780189 (rank : 23)	θ value	2.05049e-36 (rank : 16)
Query Neighborhood Hits	102	Target Neighborhood Hits	278	Shared Neighborhood Hits	34
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_HUMAN
NC score	0.777599 (rank : 24)	θ value	5.96599e-36 (rank : 17)
Query Neighborhood Hits	102	Target Neighborhood Hits	303	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
NC score	0.775823 (rank : 25)	θ value	1.32909e-35 (rank : 18)
Query Neighborhood Hits	102	Target Neighborhood Hits	284	Shared Neighborhood Hits	37
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_HUMAN
NC score	0.771681 (rank : 26)	θ value	1.73584e-35 (rank : 19)
Query Neighborhood Hits	102	Target Neighborhood Hits	369	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CNGB3_MOUSE
NC score	0.745779 (rank : 27)	θ value	3.51386e-20 (rank : 28)
Query Neighborhood Hits	102	Target Neighborhood Hits	74	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
NC score	0.735992 (rank : 28)	θ value	2.87452e-22 (rank : 27)
Query Neighborhood Hits	102	Target Neighborhood Hits	206	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB1_HUMAN
NC score	0.725491 (rank : 29)	θ value	1.33526e-19 (rank : 29)
Query Neighborhood Hits	102	Target Neighborhood Hits	222	Shared Neighborhood Hits	35
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNKH_HUMAN
NC score	0.289026 (rank : 30)	θ value	0.00020696 (rank : 30)
Query Neighborhood Hits	102	Target Neighborhood Hits	89	Shared Neighborhood Hits	54
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNK2_HUMAN
NC score	0.225198 (rank : 31)	θ value	0.00035302 (rank : 31)
Query Neighborhood Hits	102	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
NC score	0.224215 (rank : 32)	θ value	0.000602161 (rank : 32)
Query Neighborhood Hits	102	Target Neighborhood Hits	88	Shared Neighborhood Hits	51
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNKF_HUMAN
NC score	0.224154 (rank : 33)	θ value	0.0252991 (rank : 44)
Query Neighborhood Hits	102	Target Neighborhood Hits	87	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNK3_HUMAN
NC score	0.219741 (rank : 34)	θ value	0.00175202 (rank : 33)
Query Neighborhood Hits	102	Target Neighborhood Hits	88	Shared Neighborhood Hits	49
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNKA_HUMAN
NC score	0.217727 (rank : 35)	θ value	0.00509761 (rank : 37)
Query Neighborhood Hits	102	Target Neighborhood Hits	111	Shared Neighborhood Hits	54
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNK3_MOUSE
NC score	0.215210 (rank : 36)	θ value	0.00298849 (rank : 34)
Query Neighborhood Hits	102	Target Neighborhood Hits	93	Shared Neighborhood Hits	52
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK6_HUMAN
NC score	0.214853 (rank : 37)	θ value	0.00298849 (rank : 36)
Query Neighborhood Hits	102	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNKG_HUMAN
NC score	0.209922 (rank : 38)	θ value	0.00509761 (rank : 38)
Query Neighborhood Hits	102	Target Neighborhood Hits	90	Shared Neighborhood Hits	54
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNK4_HUMAN
NC score	0.205968 (rank : 39)	θ value	0.00298849 (rank : 35)
Query Neighborhood Hits	102	Target Neighborhood Hits	109	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK4_MOUSE
NC score	0.193814 (rank : 40)	θ value	0.0252991 (rank : 43)
Query Neighborhood Hits	102	Target Neighborhood Hits	118	Shared Neighborhood Hits	49
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCNK9_MOUSE
NC score	0.192051 (rank : 41)	θ value	0.0113563 (rank : 40)
Query Neighborhood Hits	102	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCNK9_HUMAN
NC score	0.191637 (rank : 42)	θ value	0.0113563 (rank : 39)
Query Neighborhood Hits	102	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK1_HUMAN
NC score	0.164815 (rank : 43)	θ value	0.279714 (rank : 49)
Query Neighborhood Hits	102	Target Neighborhood Hits	68	Shared Neighborhood Hits	44
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNK5_HUMAN
NC score	0.163699 (rank : 44)	θ value	0.279714 (rank : 50)
Query Neighborhood Hits	102	Target Neighborhood Hits	102	Shared Neighborhood Hits	53
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KCNK1_MOUSE
NC score	0.161173 (rank : 45)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	102	Target Neighborhood Hits	70	Shared Neighborhood Hits	43
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KAP0_HUMAN
NC score	0.131827 (rank : 46)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	102	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KCNKD_MOUSE
NC score	0.128288 (rank : 47)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	102	Target Neighborhood Hits	51	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KAP0_MOUSE
NC score	0.119747 (rank : 48)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	102	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KCNK7_MOUSE
NC score	0.109817 (rank : 49)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	102	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNKD_HUMAN
NC score	0.109200 (rank : 50)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	102	Target Neighborhood Hits	58	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KAP1_HUMAN
NC score	0.106360 (rank : 51)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	102	Target Neighborhood Hits	58	Shared Neighborhood Hits	26
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KCNKC_HUMAN
NC score	0.104048 (rank : 52)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	102	Target Neighborhood Hits	51	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

KAP1_MOUSE
NC score	0.104021 (rank : 53)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	102	Target Neighborhood Hits	49	Shared Neighborhood Hits	26
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KCND1_MOUSE
NC score	0.087253 (rank : 54)	θ value	0.0961366 (rank : 45)
Query Neighborhood Hits	102	Target Neighborhood Hits	165	Shared Neighborhood Hits	53
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNK7_HUMAN
NC score	0.086389 (rank : 55)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	102	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCND1_HUMAN
NC score	0.082408 (rank : 56)	θ value	0.125558 (rank : 46)
Query Neighborhood Hits	102	Target Neighborhood Hits	160	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND3_HUMAN
NC score	0.081011 (rank : 57)	θ value	0.0193708 (rank : 41)
Query Neighborhood Hits	102	Target Neighborhood Hits	162	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
NC score	0.081002 (rank : 58)	θ value	0.0193708 (rank : 42)
Query Neighborhood Hits	102	Target Neighborhood Hits	162	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND2_HUMAN
NC score	0.080929 (rank : 59)	θ value	0.125558 (rank : 47)
Query Neighborhood Hits	102	Target Neighborhood Hits	154	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
NC score	0.080928 (rank : 60)	θ value	0.125558 (rank : 48)
Query Neighborhood Hits	102	Target Neighborhood Hits	156	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KAP2_MOUSE
NC score	0.079546 (rank : 61)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	102	Target Neighborhood Hits	44	Shared Neighborhood Hits	18
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_MOUSE
NC score	0.079359 (rank : 62)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	102	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP2_HUMAN
NC score	0.077445 (rank : 63)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	102	Target Neighborhood Hits	48	Shared Neighborhood Hits	18
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_HUMAN
NC score	0.076107 (rank : 64)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	102	Target Neighborhood Hits	40	Shared Neighborhood Hits	21
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

CT152_MOUSE
NC score	0.061683 (rank : 65)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	102	Target Neighborhood Hits	38	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KCMA1_MOUSE
NC score	0.058500 (rank : 66)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	102	Target Neighborhood Hits	94	Shared Neighborhood Hits	43
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCMA1_HUMAN
NC score	0.058362 (rank : 67)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	102	Target Neighborhood Hits	96	Shared Neighborhood Hits	43
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCNQ3_MOUSE
NC score	0.054324 (rank : 68)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	102	Target Neighborhood Hits	105	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_HUMAN
NC score	0.053019 (rank : 69)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	102	Target Neighborhood Hits	114	Shared Neighborhood Hits	47
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNS2_HUMAN
NC score	0.051820 (rank : 70)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	102	Target Neighborhood Hits	129	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_MOUSE
NC score	0.051215 (rank : 71)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	102	Target Neighborhood Hits	130	Shared Neighborhood Hits	38
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNQ4_HUMAN
NC score	0.049988 (rank : 72)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	102	Target Neighborhood Hits	136	Shared Neighborhood Hits	42
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNG4_HUMAN
NC score	0.044242 (rank : 73)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	102	Target Neighborhood Hits	99	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNB2_HUMAN
NC score	0.043672 (rank : 74)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	102	Target Neighborhood Hits	212	Shared Neighborhood Hits	39
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNB1_MOUSE
NC score	0.042467 (rank : 75)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	102	Target Neighborhood Hits	154	Shared Neighborhood Hits	40
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB1_HUMAN
NC score	0.042421 (rank : 76)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	102	Target Neighborhood Hits	169	Shared Neighborhood Hits	39
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNG2_HUMAN
NC score	0.041704 (rank : 77)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	102	Target Neighborhood Hits	83	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNT1_HUMAN
NC score	0.040336 (rank : 78)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	102	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	Q5JUK3, Q9P2C5	Gene names	KCNT1, KIAA1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1 (KCa4.1).

KGP1B_MOUSE
NC score	0.040202 (rank : 79)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	102	Target Neighborhood Hits	922	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_HUMAN
NC score	0.040055 (rank : 80)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	102	Target Neighborhood Hits	921	Shared Neighborhood Hits	35
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
NC score	0.040017 (rank : 81)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	102	Target Neighborhood Hits	901	Shared Neighborhood Hits	35
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KCNA2_MOUSE
NC score	0.038589 (rank : 82)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	102	Target Neighborhood Hits	102	Shared Neighborhood Hits	39
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA4_HUMAN
NC score	0.038289 (rank : 83)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	102	Target Neighborhood Hits	108	Shared Neighborhood Hits	42
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNQ5_HUMAN
NC score	0.037240 (rank : 84)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	102	Target Neighborhood Hits	163	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNA2_HUMAN
NC score	0.037066 (rank : 85)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	102	Target Neighborhood Hits	101	Shared Neighborhood Hits	39
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNS1_HUMAN
NC score	0.036480 (rank : 86)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	102	Target Neighborhood Hits	116	Shared Neighborhood Hits	29
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNT1_MOUSE
NC score	0.035156 (rank : 87)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	102	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZPR4, Q8C3E7	Gene names	Kcnt1, Kiaa1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1.

KGP2_HUMAN
NC score	0.029240 (rank : 88)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	102	Target Neighborhood Hits	1023	Shared Neighborhood Hits	28
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_MOUSE
NC score	0.028518 (rank : 89)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	102	Target Neighborhood Hits	1029	Shared Neighborhood Hits	27
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

DTX3_MOUSE
NC score	0.020657 (rank : 90)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	102	Target Neighborhood Hits	202	Shared Neighborhood Hits	5
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

DEK_MOUSE
NC score	0.020597 (rank : 91)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	102	Target Neighborhood Hits	280	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

DTX3_HUMAN
NC score	0.019588 (rank : 92)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	102	Target Neighborhood Hits	198	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

NOLC1_HUMAN
NC score	0.015211 (rank : 93)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	102	Target Neighborhood Hits	452	Shared Neighborhood Hits	6
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

ARMX5_MOUSE
NC score	0.014391 (rank : 94)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	102	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UZB0	Gene names	Armcx5
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 5.

CLP46_MOUSE
NC score	0.013039 (rank : 95)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	102	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYB9, Q8R0H7	Gene names	Clp46
Domain Architecture	No domain graphic available
Description	CAP10-like 46 kDa protein precursor.

SYV_HUMAN
NC score	0.012131 (rank : 96)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	102	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P26640, Q5JQ90, Q96E77, Q9UQM2	Gene names	VARS, G7A, VARS2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

FMN1B_MOUSE
NC score	0.011860 (rank : 97)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	102	Target Neighborhood Hits	447	Shared Neighborhood Hits	8
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

TRDN_HUMAN
NC score	0.010928 (rank : 98)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	102	Target Neighborhood Hits	542	Shared Neighborhood Hits	10
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TSH2_MOUSE
NC score	0.009109 (rank : 99)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	102	Target Neighborhood Hits	467	Shared Neighborhood Hits	5
SwissProt Accessions	Q68FE9, Q5DTF1, Q6AXH5, Q9JL71	Gene names	Tshz2, Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (SDCCAG33-like protein).

DMP1_HUMAN
NC score	0.009052 (rank : 100)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	102	Target Neighborhood Hits	491	Shared Neighborhood Hits	9
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

TRAF6_HUMAN
NC score	0.008695 (rank : 101)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	102	Target Neighborhood Hits	267	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

PEX14_MOUSE
NC score	0.008481 (rank : 102)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	102	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R0A0	Gene names	Pex14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

TFE3_HUMAN
NC score	0.008179 (rank : 103)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	102	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

GON4L_HUMAN
NC score	0.007960 (rank : 104)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	102	Target Neighborhood Hits	555	Shared Neighborhood Hits	10
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

AIM1_HUMAN
NC score	0.007407 (rank : 105)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	102	Target Neighborhood Hits	247	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

BPTF_HUMAN
NC score	0.006084 (rank : 106)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	102	Target Neighborhood Hits	786	Shared Neighborhood Hits	12
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

APC_MOUSE
NC score	0.005591 (rank : 107)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	102	Target Neighborhood Hits	441	Shared Neighborhood Hits	7
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

CORO6_MOUSE
NC score	0.003952 (rank : 108)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	102	Target Neighborhood Hits	246	Shared Neighborhood Hits	5
SwissProt Accessions	Q920M5, Q920M3, Q920M4	Gene names	Coro6
Domain Architecture	No domain graphic available
Description	Coronin-6 (Clipin E).

CUTL1_MOUSE
NC score	0.003710 (rank : 109)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	102	Target Neighborhood Hits	1620	Shared Neighborhood Hits	16
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

BRWD1_HUMAN
NC score	0.002423 (rank : 110)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	102	Target Neighborhood Hits	448	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

PLCB2_HUMAN
NC score	0.002133 (rank : 111)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	102	Target Neighborhood Hits	608	Shared Neighborhood Hits	10
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

DSPP_HUMAN
NC score	0.001566 (rank : 112)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	102	Target Neighborhood Hits	645	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

GCR_HUMAN
NC score	0.000286 (rank : 113)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	102	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

TPR_HUMAN
NC score	0.000234 (rank : 114)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	102	Target Neighborhood Hits	1921	Shared Neighborhood Hits	24
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

MYH13_HUMAN
NC score	-0.000811 (rank : 115)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	102	Target Neighborhood Hits	1504	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

RAI14_MOUSE
NC score	-0.001645 (rank : 116)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	102	Target Neighborhood Hits	1505	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).