Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : CAC1E_HUMAN

For an explanation of this page, click here

CAC1E_HUMAN
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAC1A_HUMAN
θ value	0 (rank : 1)	NC score	0.969165 (rank : 6)
Query Neighborhood Hits	148	Target Neighborhood Hits	387	Shared Neighborhood Hits	73
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_MOUSE
θ value	0 (rank : 2)	NC score	0.978462 (rank : 3)
Query Neighborhood Hits	148	Target Neighborhood Hits	267	Shared Neighborhood Hits	75
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_HUMAN
θ value	0 (rank : 3)	NC score	0.977070 (rank : 4)
Query Neighborhood Hits	148	Target Neighborhood Hits	257	Shared Neighborhood Hits	69
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1B_MOUSE
θ value	0 (rank : 4)	NC score	0.973819 (rank : 5)
Query Neighborhood Hits	148	Target Neighborhood Hits	351	Shared Neighborhood Hits	74
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1C_HUMAN
θ value	0 (rank : 5)	NC score	0.956906 (rank : 13)
Query Neighborhood Hits	148	Target Neighborhood Hits	158	Shared Neighborhood Hits	57
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1C_MOUSE
θ value	0 (rank : 6)	NC score	0.958446 (rank : 12)
Query Neighborhood Hits	148	Target Neighborhood Hits	130	Shared Neighborhood Hits	57
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1D_HUMAN
θ value	0 (rank : 7)	NC score	0.959340 (rank : 11)
Query Neighborhood Hits	148	Target Neighborhood Hits	118	Shared Neighborhood Hits	58
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1E_HUMAN
θ value	0 (rank : 8)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	148	Target Neighborhood Hits	148	Shared Neighborhood Hits	148
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	0 (rank : 9)	NC score	0.997796 (rank : 2)
Query Neighborhood Hits	148	Target Neighborhood Hits	167	Shared Neighborhood Hits	113
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1F_HUMAN
θ value	0 (rank : 10)	NC score	0.960135 (rank : 10)
Query Neighborhood Hits	148	Target Neighborhood Hits	141	Shared Neighborhood Hits	59
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_MOUSE
θ value	0 (rank : 11)	NC score	0.960357 (rank : 9)
Query Neighborhood Hits	148	Target Neighborhood Hits	142	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1S_HUMAN
θ value	0 (rank : 12)	NC score	0.961510 (rank : 8)
Query Neighborhood Hits	148	Target Neighborhood Hits	92	Shared Neighborhood Hits	53
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1S_MOUSE
θ value	0 (rank : 13)	NC score	0.961896 (rank : 7)
Query Neighborhood Hits	148	Target Neighborhood Hits	98	Shared Neighborhood Hits	56
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SCN9A_HUMAN
θ value	2.83479e-70 (rank : 14)	NC score	0.855635 (rank : 27)
Query Neighborhood Hits	148	Target Neighborhood Hits	157	Shared Neighborhood Hits	64
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN2A_HUMAN
θ value	3.70236e-70 (rank : 15)	NC score	0.855853 (rank : 25)
Query Neighborhood Hits	148	Target Neighborhood Hits	157	Shared Neighborhood Hits	61
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN4A_HUMAN
θ value	4.83544e-70 (rank : 16)	NC score	0.865237 (rank : 20)
Query Neighborhood Hits	148	Target Neighborhood Hits	133	Shared Neighborhood Hits	64
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN1A_HUMAN
θ value	3.13423e-69 (rank : 17)	NC score	0.855226 (rank : 28)
Query Neighborhood Hits	148	Target Neighborhood Hits	148	Shared Neighborhood Hits	64
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

CAC1G_HUMAN
θ value	6.98233e-69 (rank : 18)	NC score	0.863269 (rank : 21)
Query Neighborhood Hits	148	Target Neighborhood Hits	587	Shared Neighborhood Hits	66
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SC11A_HUMAN
θ value	6.98233e-69 (rank : 19)	NC score	0.869875 (rank : 18)
Query Neighborhood Hits	148	Target Neighborhood Hits	111	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SC10A_MOUSE
θ value	1.19101e-68 (rank : 20)	NC score	0.857307 (rank : 24)
Query Neighborhood Hits	148	Target Neighborhood Hits	107	Shared Neighborhood Hits	63
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN3A_HUMAN
θ value	1.19101e-68 (rank : 21)	NC score	0.857852 (rank : 23)
Query Neighborhood Hits	148	Target Neighborhood Hits	115	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

CAC1H_MOUSE
θ value	1.5555e-68 (rank : 22)	NC score	0.881609 (rank : 15)
Query Neighborhood Hits	148	Target Neighborhood Hits	230	Shared Neighborhood Hits	62
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1I_HUMAN
θ value	2.03155e-68 (rank : 23)	NC score	0.904259 (rank : 14)
Query Neighborhood Hits	148	Target Neighborhood Hits	138	Shared Neighborhood Hits	62
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1H_HUMAN
θ value	3.4653e-68 (rank : 24)	NC score	0.877341 (rank : 16)
Query Neighborhood Hits	148	Target Neighborhood Hits	307	Shared Neighborhood Hits	63
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

SCN8A_HUMAN
θ value	5.91091e-68 (rank : 25)	NC score	0.855689 (rank : 26)
Query Neighborhood Hits	148	Target Neighborhood Hits	135	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
θ value	5.91091e-68 (rank : 26)	NC score	0.853388 (rank : 29)
Query Neighborhood Hits	148	Target Neighborhood Hits	136	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SC11A_MOUSE
θ value	5.53243e-66 (rank : 27)	NC score	0.871562 (rank : 17)
Query Neighborhood Hits	148	Target Neighborhood Hits	116	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SC10A_HUMAN
θ value	7.2256e-66 (rank : 28)	NC score	0.852816 (rank : 30)
Query Neighborhood Hits	148	Target Neighborhood Hits	116	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SCN5A_HUMAN
θ value	7.2256e-66 (rank : 29)	NC score	0.866894 (rank : 19)
Query Neighborhood Hits	148	Target Neighborhood Hits	145	Shared Neighborhood Hits	62
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SCN7A_HUMAN
θ value	1.45929e-58 (rank : 30)	NC score	0.862604 (rank : 22)
Query Neighborhood Hits	148	Target Neighborhood Hits	135	Shared Neighborhood Hits	51
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

PKD2_MOUSE
θ value	1.17247e-07 (rank : 31)	NC score	0.345704 (rank : 34)
Query Neighborhood Hits	148	Target Neighborhood Hits	99	Shared Neighborhood Hits	41
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PK2L2_MOUSE
θ value	1.29631e-06 (rank : 32)	NC score	0.348640 (rank : 33)
Query Neighborhood Hits	148	Target Neighborhood Hits	84	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L2_HUMAN
θ value	2.88788e-06 (rank : 33)	NC score	0.381345 (rank : 31)
Query Neighborhood Hits	148	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L1_HUMAN
θ value	1.43324e-05 (rank : 34)	NC score	0.354260 (rank : 32)
Query Neighborhood Hits	148	Target Neighborhood Hits	132	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

KCND3_HUMAN
θ value	3.19293e-05 (rank : 35)	NC score	0.189098 (rank : 42)
Query Neighborhood Hits	148	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	3.19293e-05 (rank : 36)	NC score	0.189169 (rank : 41)
Query Neighborhood Hits	148	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

PKD2_HUMAN
θ value	5.44631e-05 (rank : 37)	NC score	0.330846 (rank : 35)
Query Neighborhood Hits	148	Target Neighborhood Hits	105	Shared Neighborhood Hits	42
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCND2_HUMAN
θ value	9.29e-05 (rank : 38)	NC score	0.182792 (rank : 46)
Query Neighborhood Hits	148	Target Neighborhood Hits	154	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	9.29e-05 (rank : 39)	NC score	0.182970 (rank : 45)
Query Neighborhood Hits	148	Target Neighborhood Hits	156	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCNF1_HUMAN
θ value	0.000461057 (rank : 40)	NC score	0.235788 (rank : 36)
Query Neighborhood Hits	148	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNV2_HUMAN
θ value	0.000786445 (rank : 41)	NC score	0.226002 (rank : 37)
Query Neighborhood Hits	148	Target Neighborhood Hits	137	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCND1_MOUSE
θ value	0.00175202 (rank : 42)	NC score	0.170798 (rank : 47)
Query Neighborhood Hits	148	Target Neighborhood Hits	165	Shared Neighborhood Hits	52
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
θ value	0.00228821 (rank : 43)	NC score	0.166893 (rank : 48)
Query Neighborhood Hits	148	Target Neighborhood Hits	160	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNS2_MOUSE
θ value	0.00390308 (rank : 44)	NC score	0.201433 (rank : 39)
Query Neighborhood Hits	148	Target Neighborhood Hits	130	Shared Neighborhood Hits	53
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
θ value	0.00869519 (rank : 45)	NC score	0.196987 (rank : 40)
Query Neighborhood Hits	148	Target Neighborhood Hits	129	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

MCLN2_MOUSE
θ value	0.0148317 (rank : 46)	NC score	0.083502 (rank : 65)
Query Neighborhood Hits	148	Target Neighborhood Hits	31	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

TGON2_HUMAN
θ value	0.0148317 (rank : 47)	NC score	0.032790 (rank : 100)
Query Neighborhood Hits	148	Target Neighborhood Hits	1037	Shared Neighborhood Hits	41
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

NIPBL_HUMAN
θ value	0.0193708 (rank : 48)	NC score	0.049269 (rank : 92)
Query Neighborhood Hits	148	Target Neighborhood Hits	1311	Shared Neighborhood Hits	44
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

TRPM8_MOUSE
θ value	0.0330416 (rank : 49)	NC score	0.062467 (rank : 80)
Query Neighborhood Hits	148	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

KCNB2_HUMAN
θ value	0.0736092 (rank : 50)	NC score	0.203431 (rank : 38)
Query Neighborhood Hits	148	Target Neighborhood Hits	212	Shared Neighborhood Hits	58
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

RBBP6_HUMAN
θ value	0.0961366 (rank : 51)	NC score	0.034331 (rank : 98)
Query Neighborhood Hits	148	Target Neighborhood Hits	1135	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TRPM8_HUMAN
θ value	0.0961366 (rank : 52)	NC score	0.056794 (rank : 83)
Query Neighborhood Hits	148	Target Neighborhood Hits	65	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

CASC3_MOUSE
θ value	0.163984 (rank : 53)	NC score	0.024124 (rank : 106)
Query Neighborhood Hits	148	Target Neighborhood Hits	333	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

GPR63_MOUSE
θ value	0.163984 (rank : 54)	NC score	0.007639 (rank : 130)
Query Neighborhood Hits	148	Target Neighborhood Hits	774	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQQ3	Gene names	Gpr63
Domain Architecture
Description	Probable G-protein coupled receptor 63 (PSP24-beta) (PSP24-2).

TPTE2_HUMAN
θ value	0.163984 (rank : 55)	NC score	0.143716 (rank : 50)
Query Neighborhood Hits	148	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

FAT2_HUMAN
θ value	0.21417 (rank : 56)	NC score	0.005947 (rank : 140)
Query Neighborhood Hits	148	Target Neighborhood Hits	507	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

KCNC4_MOUSE
θ value	0.21417 (rank : 57)	NC score	0.121209 (rank : 56)
Query Neighborhood Hits	148	Target Neighborhood Hits	130	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNQ5_HUMAN
θ value	0.21417 (rank : 58)	NC score	0.062011 (rank : 81)
Query Neighborhood Hits	148	Target Neighborhood Hits	163	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

NPBL_MOUSE
θ value	0.21417 (rank : 59)	NC score	0.056572 (rank : 84)
Query Neighborhood Hits	148	Target Neighborhood Hits	1041	Shared Neighborhood Hits	41
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

RBBP6_MOUSE
θ value	0.21417 (rank : 60)	NC score	0.039715 (rank : 95)
Query Neighborhood Hits	148	Target Neighborhood Hits	1014	Shared Neighborhood Hits	35
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TXND2_MOUSE
θ value	0.21417 (rank : 61)	NC score	0.016951 (rank : 109)
Query Neighborhood Hits	148	Target Neighborhood Hits	828	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

NEST_HUMAN
θ value	0.279714 (rank : 62)	NC score	0.006614 (rank : 134)
Query Neighborhood Hits	148	Target Neighborhood Hits	1305	Shared Neighborhood Hits	26
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

CENPC_MOUSE
θ value	0.365318 (rank : 63)	NC score	0.034144 (rank : 99)
Query Neighborhood Hits	148	Target Neighborhood Hits	154	Shared Neighborhood Hits	13
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

KCNB1_HUMAN
θ value	0.365318 (rank : 64)	NC score	0.188591 (rank : 44)
Query Neighborhood Hits	148	Target Neighborhood Hits	169	Shared Neighborhood Hits	53
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	0.365318 (rank : 65)	NC score	0.188699 (rank : 43)
Query Neighborhood Hits	148	Target Neighborhood Hits	154	Shared Neighborhood Hits	54
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNG3_HUMAN
θ value	0.365318 (rank : 66)	NC score	0.107983 (rank : 59)
Query Neighborhood Hits	148	Target Neighborhood Hits	91	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

MCPH1_MOUSE
θ value	0.365318 (rank : 67)	NC score	0.037723 (rank : 97)
Query Neighborhood Hits	148	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

KCNC4_HUMAN
θ value	0.47712 (rank : 68)	NC score	0.128484 (rank : 54)
Query Neighborhood Hits	148	Target Neighborhood Hits	141	Shared Neighborhood Hits	50
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

ZN318_MOUSE
θ value	0.47712 (rank : 69)	NC score	0.023327 (rank : 107)
Query Neighborhood Hits	148	Target Neighborhood Hits	642	Shared Neighborhood Hits	23
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

GPR63_HUMAN
θ value	0.62314 (rank : 70)	NC score	0.005206 (rank : 147)
Query Neighborhood Hits	148	Target Neighborhood Hits	776	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZJ6, Q9UJH3	Gene names	GPR63, PSP24B
Domain Architecture
Description	Probable G-protein coupled receptor 63 (PSP24-beta) (PSP24-2).

KCNC1_HUMAN
θ value	0.62314 (rank : 71)	NC score	0.134879 (rank : 52)
Query Neighborhood Hits	148	Target Neighborhood Hits	133	Shared Neighborhood Hits	48
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

CDKL5_HUMAN
θ value	0.813845 (rank : 72)	NC score	-0.002029 (rank : 171)
Query Neighborhood Hits	148	Target Neighborhood Hits	967	Shared Neighborhood Hits	14
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

EVI1_HUMAN
θ value	0.813845 (rank : 73)	NC score	-0.003713 (rank : 174)
Query Neighborhood Hits	148	Target Neighborhood Hits	924	Shared Neighborhood Hits	7
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

KCNC1_MOUSE
θ value	0.813845 (rank : 74)	NC score	0.132893 (rank : 53)
Query Neighborhood Hits	148	Target Neighborhood Hits	133	Shared Neighborhood Hits	48
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

TCP10_HUMAN
θ value	0.813845 (rank : 75)	NC score	0.038979 (rank : 96)
Query Neighborhood Hits	148	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

IRAK1_HUMAN
θ value	1.06291 (rank : 76)	NC score	-0.000324 (rank : 167)
Query Neighborhood Hits	148	Target Neighborhood Hits	820	Shared Neighborhood Hits	6
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

WNK1_HUMAN
θ value	1.06291 (rank : 77)	NC score	-0.001340 (rank : 170)
Query Neighborhood Hits	148	Target Neighborhood Hits	1158	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

KCNG3_MOUSE
θ value	1.38821 (rank : 78)	NC score	0.104662 (rank : 61)
Query Neighborhood Hits	148	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

TTC16_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.027723 (rank : 102)
Query Neighborhood Hits	148	Target Neighborhood Hits	417	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

CD45_HUMAN
θ value	1.81305 (rank : 80)	NC score	0.002533 (rank : 159)
Query Neighborhood Hits	148	Target Neighborhood Hits	243	Shared Neighborhood Hits	9
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

FA47A_HUMAN
θ value	1.81305 (rank : 81)	NC score	0.015332 (rank : 113)
Query Neighborhood Hits	148	Target Neighborhood Hits	451	Shared Neighborhood Hits	14
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

MATR3_MOUSE
θ value	1.81305 (rank : 82)	NC score	0.015735 (rank : 112)
Query Neighborhood Hits	148	Target Neighborhood Hits	321	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

PDZD2_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.011958 (rank : 118)
Query Neighborhood Hits	148	Target Neighborhood Hits	772	Shared Neighborhood Hits	20
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

TCF20_MOUSE
θ value	1.81305 (rank : 84)	NC score	0.025021 (rank : 105)
Query Neighborhood Hits	148	Target Neighborhood Hits	396	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TPTE_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.100213 (rank : 62)
Query Neighborhood Hits	148	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

FOXJ2_MOUSE
θ value	2.36792 (rank : 86)	NC score	0.003103 (rank : 156)
Query Neighborhood Hits	148	Target Neighborhood Hits	151	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ES18	Gene names	Foxj2, Fhx
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

PININ_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.021385 (rank : 108)
Query Neighborhood Hits	148	Target Neighborhood Hits	753	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PKDRE_MOUSE
θ value	2.36792 (rank : 88)	NC score	0.083504 (rank : 64)
Query Neighborhood Hits	148	Target Neighborhood Hits	76	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

DIDO1_HUMAN
θ value	3.0926 (rank : 89)	NC score	0.027432 (rank : 103)
Query Neighborhood Hits	148	Target Neighborhood Hits	960	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

KI67_HUMAN
θ value	3.0926 (rank : 90)	NC score	0.013247 (rank : 116)
Query Neighborhood Hits	148	Target Neighborhood Hits	581	Shared Neighborhood Hits	21
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

TAIP2_HUMAN
θ value	3.0926 (rank : 91)	NC score	0.009586 (rank : 122)
Query Neighborhood Hits	148	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WYN3	Gene names	TAIP2
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 2 (TAIP-2).

TRPC4_MOUSE
θ value	3.0926 (rank : 92)	NC score	0.040476 (rank : 94)
Query Neighborhood Hits	148	Target Neighborhood Hits	141	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

CD2_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.013389 (rank : 114)
Query Neighborhood Hits	148	Target Neighborhood Hits	504	Shared Neighborhood Hits	16
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

DHX36_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.006374 (rank : 137)
Query Neighborhood Hits	148	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

IKKE_MOUSE
θ value	4.03905 (rank : 95)	NC score	-0.002541 (rank : 172)
Query Neighborhood Hits	148	Target Neighborhood Hits	848	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0T8	Gene names	Ikbke, Ikke, Ikki
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

ITSN1_MOUSE
θ value	4.03905 (rank : 96)	NC score	0.000716 (rank : 164)
Query Neighborhood Hits	148	Target Neighborhood Hits	1669	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

KCNS3_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.166713 (rank : 49)
Query Neighborhood Hits	148	Target Neighborhood Hits	125	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

LMO7_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.008124 (rank : 128)
Query Neighborhood Hits	148	Target Neighborhood Hits	507	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

RB15B_MOUSE
θ value	4.03905 (rank : 99)	NC score	0.016045 (rank : 111)
Query Neighborhood Hits	148	Target Neighborhood Hits	284	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PHZ5, Q8C6G2	Gene names	Rbm15b
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

TRI55_HUMAN
θ value	4.03905 (rank : 100)	NC score	0.005083 (rank : 148)
Query Neighborhood Hits	148	Target Neighborhood Hits	292	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRPC4_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.041955 (rank : 93)
Query Neighborhood Hits	148	Target Neighborhood Hits	140	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

VN1B8_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.005376 (rank : 144)
Query Neighborhood Hits	148	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQ45	Gene names	V1rb8, V1ra13
Domain Architecture	No domain graphic available
Description	Vomeronasal type-1 receptor B8 (Vomeronasal type-1 receptor A13).

AK1A1_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.006563 (rank : 135)
Query Neighborhood Hits	148	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	P14550	Gene names	AKR1A1, ALDR1, ALR
Domain Architecture
Description	Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde reductase) (Aldo- keto reductase family 1 member A1).

ARNT_MOUSE
θ value	5.27518 (rank : 104)	NC score	0.002932 (rank : 158)
Query Neighborhood Hits	148	Target Neighborhood Hits	213	Shared Neighborhood Hits	9
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

CT075_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.001335 (rank : 163)
Query Neighborhood Hits	148	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

CT128_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.009072 (rank : 125)
Query Neighborhood Hits	148	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQN1, Q5JWN6, Q8N276	Gene names	C20orf128
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf128.

EP300_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.008709 (rank : 127)
Query Neighborhood Hits	148	Target Neighborhood Hits	821	Shared Neighborhood Hits	25
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ITSN1_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.000032 (rank : 166)
Query Neighborhood Hits	148	Target Neighborhood Hits	1757	Shared Neighborhood Hits	27
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

LIMA1_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.005686 (rank : 142)
Query Neighborhood Hits	148	Target Neighborhood Hits	309	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

MATR3_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.013243 (rank : 117)
Query Neighborhood Hits	148	Target Neighborhood Hits	325	Shared Neighborhood Hits	10
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MLL2_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.016077 (rank : 110)
Query Neighborhood Hits	148	Target Neighborhood Hits	1788	Shared Neighborhood Hits	38
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

RB15B_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.009620 (rank : 121)
Query Neighborhood Hits	148	Target Neighborhood Hits	251	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NDT2, Q6QE19, Q9BV96	Gene names	RBM15B
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

SRRM2_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.031368 (rank : 101)
Query Neighborhood Hits	148	Target Neighborhood Hits	1296	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TSN17_HUMAN
θ value	5.27518 (rank : 114)	NC score	0.006299 (rank : 138)
Query Neighborhood Hits	148	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q96FV3, Q96S98, Q9UKB9	Gene names	TSPAN17, FBXO23, TM4SF17
Domain Architecture	No domain graphic available
Description	Tetraspanin-17 (Tspan-17) (Transmembrane 4 superfamily member 17) (Tetraspan protein SB134) (F-box only protein 23).

TSN17_MOUSE
θ value	5.27518 (rank : 115)	NC score	0.006489 (rank : 136)
Query Neighborhood Hits	148	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D7W4, Q91VI6	Gene names	Tspan17, Fbxo23, Tm4sf17
Domain Architecture	No domain graphic available
Description	Tetraspanin-17 (Tspan-17) (Transmembrane 4 superfamily member 17) (Tetraspan protein SB134) (F-box only protein 23).

TTC28_HUMAN
θ value	5.27518 (rank : 116)	NC score	0.007638 (rank : 131)
Query Neighborhood Hits	148	Target Neighborhood Hits	271	Shared Neighborhood Hits	13
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

TUFT1_MOUSE
θ value	5.27518 (rank : 117)	NC score	0.001501 (rank : 162)
Query Neighborhood Hits	148	Target Neighborhood Hits	732	Shared Neighborhood Hits	9
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

CO4A2_HUMAN
θ value	6.88961 (rank : 118)	NC score	-0.000393 (rank : 168)
Query Neighborhood Hits	148	Target Neighborhood Hits	454	Shared Neighborhood Hits	9
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

DHX36_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.005912 (rank : 141)
Query Neighborhood Hits	148	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

PKDRE_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.107096 (rank : 60)
Query Neighborhood Hits	148	Target Neighborhood Hits	64	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

SPTB2_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.003556 (rank : 153)
Query Neighborhood Hits	148	Target Neighborhood Hits	748	Shared Neighborhood Hits	17
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
θ value	6.88961 (rank : 122)	NC score	0.003521 (rank : 154)
Query Neighborhood Hits	148	Target Neighborhood Hits	770	Shared Neighborhood Hits	18
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTN2_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.003979 (rank : 151)
Query Neighborhood Hits	148	Target Neighborhood Hits	535	Shared Neighborhood Hits	10
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

TAF3_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.009888 (rank : 120)
Query Neighborhood Hits	148	Target Neighborhood Hits	568	Shared Neighborhood Hits	24
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAIP2_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.007946 (rank : 129)
Query Neighborhood Hits	148	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	P59055	Gene names	Taip2
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 2 (TAIP-2).

TLR8_MOUSE
θ value	6.88961 (rank : 126)	NC score	0.000471 (rank : 165)
Query Neighborhood Hits	148	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	P58682, Q91XI7	Gene names	Tlr8
Domain Architecture
Description	Toll-like receptor 8 precursor.

TTF2_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.006198 (rank : 139)
Query Neighborhood Hits	148	Target Neighborhood Hits	364	Shared Neighborhood Hits	16
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

UBP6_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.001510 (rank : 161)
Query Neighborhood Hits	148	Target Neighborhood Hits	188	Shared Neighborhood Hits	7
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

ULK2_MOUSE
θ value	6.88961 (rank : 129)	NC score	-0.002824 (rank : 173)
Query Neighborhood Hits	148	Target Neighborhood Hits	943	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

UN45A_MOUSE
θ value	6.88961 (rank : 130)	NC score	0.004740 (rank : 150)
Query Neighborhood Hits	148	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q99KD5, Q3TKV6, Q8BFT3, Q8C157	Gene names	Unc45a, Smap1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Stromal membrane-associated protein 1) (Smap-1).

AK1A1_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.004947 (rank : 149)
Query Neighborhood Hits	148	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JII6, Q9CQI5, Q9CQT8, Q9CT53, Q9D012, Q9D016, Q9D0I7, Q9D0P3	Gene names	Akr1a1, Akr1a4
Domain Architecture
Description	Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde reductase) (Aldo- keto reductase family 1 member A1).

DC1L2_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.009283 (rank : 124)
Query Neighborhood Hits	148	Target Neighborhood Hits	173	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

GON4L_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.005277 (rank : 146)
Query Neighborhood Hits	148	Target Neighborhood Hits	455	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

IRF7_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.002979 (rank : 157)
Query Neighborhood Hits	148	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

JPH2_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.010912 (rank : 119)
Query Neighborhood Hits	148	Target Neighborhood Hits	639	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

KCNS1_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.141141 (rank : 51)
Query Neighborhood Hits	148	Target Neighborhood Hits	116	Shared Neighborhood Hits	51
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

LSM11_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.006684 (rank : 133)
Query Neighborhood Hits	148	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BUV6	Gene names	Lsm11
Domain Architecture	No domain graphic available
Description	U7 snRNA-associated Sm-like protein LSm11.

MBN3_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.008865 (rank : 126)
Query Neighborhood Hits	148	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R003	Gene names	Mbnl3, Chcr, Mbxl
Domain Architecture	No domain graphic available
Description	Muscleblind-like X-linked protein (Muscleblind-like protein 3) (Cys3His CCG1-required protein) (Protein MCHCR).

NCOR1_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.003478 (rank : 155)
Query Neighborhood Hits	148	Target Neighborhood Hits	577	Shared Neighborhood Hits	18
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NKTR_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.009330 (rank : 123)
Query Neighborhood Hits	148	Target Neighborhood Hits	658	Shared Neighborhood Hits	28
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PCDG5_HUMAN
θ value	8.99809 (rank : 141)	NC score	-0.000663 (rank : 169)
Query Neighborhood Hits	148	Target Neighborhood Hits	159	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5G8, Q9Y5D2	Gene names	PCDHGA5
Domain Architecture
Description	Protocadherin gamma A5 precursor (PCDH-gamma-A5).

PDE3A_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.001624 (rank : 160)
Query Neighborhood Hits	148	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PO6F2_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.013359 (rank : 115)
Query Neighborhood Hits	148	Target Neighborhood Hits	618	Shared Neighborhood Hits	17
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

SYTL2_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.003851 (rank : 152)
Query Neighborhood Hits	148	Target Neighborhood Hits	248	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

TARA_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.026907 (rank : 104)
Query Neighborhood Hits	148	Target Neighborhood Hits	1626	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TCRG1_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.006846 (rank : 132)
Query Neighborhood Hits	148	Target Neighborhood Hits	929	Shared Neighborhood Hits	28
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.005336 (rank : 145)
Query Neighborhood Hits	148	Target Neighborhood Hits	947	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

UBP28_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.005581 (rank : 143)
Query Neighborhood Hits	148	Target Neighborhood Hits	178	Shared Neighborhood Hits	10
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

KCNA1_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.081726 (rank : 66)
Query Neighborhood Hits	148	Target Neighborhood Hits	104	Shared Neighborhood Hits	35
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA1_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.083575 (rank : 63)
Query Neighborhood Hits	148	Target Neighborhood Hits	103	Shared Neighborhood Hits	36
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA2_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.075116 (rank : 70)
Query Neighborhood Hits	148	Target Neighborhood Hits	101	Shared Neighborhood Hits	32
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.075994 (rank : 69)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA3_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.066997 (rank : 76)
Query Neighborhood Hits	148	Target Neighborhood Hits	101	Shared Neighborhood Hits	31
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.066022 (rank : 77)
Query Neighborhood Hits	148	Target Neighborhood Hits	103	Shared Neighborhood Hits	29
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA4_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.056075 (rank : 86)
Query Neighborhood Hits	148	Target Neighborhood Hits	108	Shared Neighborhood Hits	24
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA4_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.056427 (rank : 85)
Query Neighborhood Hits	148	Target Neighborhood Hits	98	Shared Neighborhood Hits	24
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA5_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.063912 (rank : 78)
Query Neighborhood Hits	148	Target Neighborhood Hits	124	Shared Neighborhood Hits	28
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNA5_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.069565 (rank : 74)
Query Neighborhood Hits	148	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNA6_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.072451 (rank : 71)
Query Neighborhood Hits	148	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA6_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.077984 (rank : 68)
Query Neighborhood Hits	148	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNC3_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.110329 (rank : 57)
Query Neighborhood Hits	148	Target Neighborhood Hits	256	Shared Neighborhood Hits	53
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.108877 (rank : 58)
Query Neighborhood Hits	148	Target Neighborhood Hits	173	Shared Neighborhood Hits	49
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNG1_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.070017 (rank : 73)
Query Neighborhood Hits	148	Target Neighborhood Hits	103	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG2_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.067485 (rank : 75)
Query Neighborhood Hits	148	Target Neighborhood Hits	83	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNG4_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.062840 (rank : 79)
Query Neighborhood Hits	148	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNQ1_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.059175 (rank : 82)
Query Neighborhood Hits	148	Target Neighborhood Hits	99	Shared Neighborhood Hits	29
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ1_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.070952 (rank : 72)
Query Neighborhood Hits	148	Target Neighborhood Hits	175	Shared Neighborhood Hits	34
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ2_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.051930 (rank : 89)
Query Neighborhood Hits	148	Target Neighborhood Hits	114	Shared Neighborhood Hits	27
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ3_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.053167 (rank : 88)
Query Neighborhood Hits	148	Target Neighborhood Hits	114	Shared Neighborhood Hits	30
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.051915 (rank : 90)
Query Neighborhood Hits	148	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ4_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.078626 (rank : 67)
Query Neighborhood Hits	148	Target Neighborhood Hits	136	Shared Neighborhood Hits	34
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNS1_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.125199 (rank : 55)
Query Neighborhood Hits	148	Target Neighborhood Hits	114	Shared Neighborhood Hits	45
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

MCLN2_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.051661 (rank : 91)
Query Neighborhood Hits	148	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IZK6, Q8N9R3	Gene names	MCOLN2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

TRPV3_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.054937 (rank : 87)
Query Neighborhood Hits	148	Target Neighborhood Hits	198	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

Hits sorted by NC score

CAC1E_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 8)
Query Neighborhood Hits	148	Target Neighborhood Hits	148	Shared Neighborhood Hits	148
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
NC score	0.997796 (rank : 2)	θ value	0 (rank : 9)
Query Neighborhood Hits	148	Target Neighborhood Hits	167	Shared Neighborhood Hits	113
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1A_MOUSE
NC score	0.978462 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	148	Target Neighborhood Hits	267	Shared Neighborhood Hits	75
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_HUMAN
NC score	0.977070 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	148	Target Neighborhood Hits	257	Shared Neighborhood Hits	69
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1B_MOUSE
NC score	0.973819 (rank : 5)	θ value	0 (rank : 4)
Query Neighborhood Hits	148	Target Neighborhood Hits	351	Shared Neighborhood Hits	74
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1A_HUMAN
NC score	0.969165 (rank : 6)	θ value	0 (rank : 1)
Query Neighborhood Hits	148	Target Neighborhood Hits	387	Shared Neighborhood Hits	73
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1S_MOUSE
NC score	0.961896 (rank : 7)	θ value	0 (rank : 13)
Query Neighborhood Hits	148	Target Neighborhood Hits	98	Shared Neighborhood Hits	56
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1S_HUMAN
NC score	0.961510 (rank : 8)	θ value	0 (rank : 12)
Query Neighborhood Hits	148	Target Neighborhood Hits	92	Shared Neighborhood Hits	53
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1F_MOUSE
NC score	0.960357 (rank : 9)	θ value	0 (rank : 11)
Query Neighborhood Hits	148	Target Neighborhood Hits	142	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_HUMAN
NC score	0.960135 (rank : 10)	θ value	0 (rank : 10)
Query Neighborhood Hits	148	Target Neighborhood Hits	141	Shared Neighborhood Hits	59
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1D_HUMAN
NC score	0.959340 (rank : 11)	θ value	0 (rank : 7)
Query Neighborhood Hits	148	Target Neighborhood Hits	118	Shared Neighborhood Hits	58
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1C_MOUSE
NC score	0.958446 (rank : 12)	θ value	0 (rank : 6)
Query Neighborhood Hits	148	Target Neighborhood Hits	130	Shared Neighborhood Hits	57
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1C_HUMAN
NC score	0.956906 (rank : 13)	θ value	0 (rank : 5)
Query Neighborhood Hits	148	Target Neighborhood Hits	158	Shared Neighborhood Hits	57
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1I_HUMAN
NC score	0.904259 (rank : 14)	θ value	2.03155e-68 (rank : 23)
Query Neighborhood Hits	148	Target Neighborhood Hits	138	Shared Neighborhood Hits	62
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1H_MOUSE
NC score	0.881609 (rank : 15)	θ value	1.5555e-68 (rank : 22)
Query Neighborhood Hits	148	Target Neighborhood Hits	230	Shared Neighborhood Hits	62
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1H_HUMAN
NC score	0.877341 (rank : 16)	θ value	3.4653e-68 (rank : 24)
Query Neighborhood Hits	148	Target Neighborhood Hits	307	Shared Neighborhood Hits	63
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

SC11A_MOUSE
NC score	0.871562 (rank : 17)	θ value	5.53243e-66 (rank : 27)
Query Neighborhood Hits	148	Target Neighborhood Hits	116	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SC11A_HUMAN
NC score	0.869875 (rank : 18)	θ value	6.98233e-69 (rank : 19)
Query Neighborhood Hits	148	Target Neighborhood Hits	111	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SCN5A_HUMAN
NC score	0.866894 (rank : 19)	θ value	7.2256e-66 (rank : 29)
Query Neighborhood Hits	148	Target Neighborhood Hits	145	Shared Neighborhood Hits	62
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SCN4A_HUMAN
NC score	0.865237 (rank : 20)	θ value	4.83544e-70 (rank : 16)
Query Neighborhood Hits	148	Target Neighborhood Hits	133	Shared Neighborhood Hits	64
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

CAC1G_HUMAN
NC score	0.863269 (rank : 21)	θ value	6.98233e-69 (rank : 18)
Query Neighborhood Hits	148	Target Neighborhood Hits	587	Shared Neighborhood Hits	66
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SCN7A_HUMAN
NC score	0.862604 (rank : 22)	θ value	1.45929e-58 (rank : 30)
Query Neighborhood Hits	148	Target Neighborhood Hits	135	Shared Neighborhood Hits	51
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SCN3A_HUMAN
NC score	0.857852 (rank : 23)	θ value	1.19101e-68 (rank : 21)
Query Neighborhood Hits	148	Target Neighborhood Hits	115	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SC10A_MOUSE
NC score	0.857307 (rank : 24)	θ value	1.19101e-68 (rank : 20)
Query Neighborhood Hits	148	Target Neighborhood Hits	107	Shared Neighborhood Hits	63
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN2A_HUMAN
NC score	0.855853 (rank : 25)	θ value	3.70236e-70 (rank : 15)
Query Neighborhood Hits	148	Target Neighborhood Hits	157	Shared Neighborhood Hits	61
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN8A_HUMAN
NC score	0.855689 (rank : 26)	θ value	5.91091e-68 (rank : 25)
Query Neighborhood Hits	148	Target Neighborhood Hits	135	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN9A_HUMAN
NC score	0.855635 (rank : 27)	θ value	2.83479e-70 (rank : 14)
Query Neighborhood Hits	148	Target Neighborhood Hits	157	Shared Neighborhood Hits	64
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN1A_HUMAN
NC score	0.855226 (rank : 28)	θ value	3.13423e-69 (rank : 17)
Query Neighborhood Hits	148	Target Neighborhood Hits	148	Shared Neighborhood Hits	64
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SCN8A_MOUSE
NC score	0.853388 (rank : 29)	θ value	5.91091e-68 (rank : 26)
Query Neighborhood Hits	148	Target Neighborhood Hits	136	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SC10A_HUMAN
NC score	0.852816 (rank : 30)	θ value	7.2256e-66 (rank : 28)
Query Neighborhood Hits	148	Target Neighborhood Hits	116	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

PK2L2_HUMAN
NC score	0.381345 (rank : 31)	θ value	2.88788e-06 (rank : 33)
Query Neighborhood Hits	148	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L1_HUMAN
NC score	0.354260 (rank : 32)	θ value	1.43324e-05 (rank : 34)
Query Neighborhood Hits	148	Target Neighborhood Hits	132	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_MOUSE
NC score	0.348640 (rank : 33)	θ value	1.29631e-06 (rank : 32)
Query Neighborhood Hits	148	Target Neighborhood Hits	84	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_MOUSE
NC score	0.345704 (rank : 34)	θ value	1.17247e-07 (rank : 31)
Query Neighborhood Hits	148	Target Neighborhood Hits	99	Shared Neighborhood Hits	41
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PKD2_HUMAN
NC score	0.330846 (rank : 35)	θ value	5.44631e-05 (rank : 37)
Query Neighborhood Hits	148	Target Neighborhood Hits	105	Shared Neighborhood Hits	42
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCNF1_HUMAN
NC score	0.235788 (rank : 36)	θ value	0.000461057 (rank : 40)
Query Neighborhood Hits	148	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNV2_HUMAN
NC score	0.226002 (rank : 37)	θ value	0.000786445 (rank : 41)
Query Neighborhood Hits	148	Target Neighborhood Hits	137	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNB2_HUMAN
NC score	0.203431 (rank : 38)	θ value	0.0736092 (rank : 50)
Query Neighborhood Hits	148	Target Neighborhood Hits	212	Shared Neighborhood Hits	58
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS2_MOUSE
NC score	0.201433 (rank : 39)	θ value	0.00390308 (rank : 44)
Query Neighborhood Hits	148	Target Neighborhood Hits	130	Shared Neighborhood Hits	53
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
NC score	0.196987 (rank : 40)	θ value	0.00869519 (rank : 45)
Query Neighborhood Hits	148	Target Neighborhood Hits	129	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCND3_MOUSE
NC score	0.189169 (rank : 41)	θ value	3.19293e-05 (rank : 36)
Query Neighborhood Hits	148	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.189098 (rank : 42)	θ value	3.19293e-05 (rank : 35)
Query Neighborhood Hits	148	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNB1_MOUSE
NC score	0.188699 (rank : 43)	θ value	0.365318 (rank : 65)
Query Neighborhood Hits	148	Target Neighborhood Hits	154	Shared Neighborhood Hits	54
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB1_HUMAN
NC score	0.188591 (rank : 44)	θ value	0.365318 (rank : 64)
Query Neighborhood Hits	148	Target Neighborhood Hits	169	Shared Neighborhood Hits	53
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCND2_MOUSE
NC score	0.182970 (rank : 45)	θ value	9.29e-05 (rank : 39)
Query Neighborhood Hits	148	Target Neighborhood Hits	156	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.182792 (rank : 46)	θ value	9.29e-05 (rank : 38)
Query Neighborhood Hits	148	Target Neighborhood Hits	154	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND1_MOUSE
NC score	0.170798 (rank : 47)	θ value	0.00175202 (rank : 42)
Query Neighborhood Hits	148	Target Neighborhood Hits	165	Shared Neighborhood Hits	52
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
NC score	0.166893 (rank : 48)	θ value	0.00228821 (rank : 43)
Query Neighborhood Hits	148	Target Neighborhood Hits	160	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNS3_HUMAN
NC score	0.166713 (rank : 49)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	148	Target Neighborhood Hits	125	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

TPTE2_HUMAN
NC score	0.143716 (rank : 50)	θ value	0.163984 (rank : 55)
Query Neighborhood Hits	148	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNS1_HUMAN
NC score	0.141141 (rank : 51)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	148	Target Neighborhood Hits	116	Shared Neighborhood Hits	51
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC1_HUMAN
NC score	0.134879 (rank : 52)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	148	Target Neighborhood Hits	133	Shared Neighborhood Hits	48
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
NC score	0.132893 (rank : 53)	θ value	0.813845 (rank : 74)
Query Neighborhood Hits	148	Target Neighborhood Hits	133	Shared Neighborhood Hits	48
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC4_HUMAN
NC score	0.128484 (rank : 54)	θ value	0.47712 (rank : 68)
Query Neighborhood Hits	148	Target Neighborhood Hits	141	Shared Neighborhood Hits	50
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNS1_MOUSE
NC score	0.125199 (rank : 55)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	148	Target Neighborhood Hits	114	Shared Neighborhood Hits	45
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC4_MOUSE
NC score	0.121209 (rank : 56)	θ value	0.21417 (rank : 57)
Query Neighborhood Hits	148	Target Neighborhood Hits	130	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNC3_HUMAN
NC score	0.110329 (rank : 57)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	148	Target Neighborhood Hits	256	Shared Neighborhood Hits	53
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
NC score	0.108877 (rank : 58)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	148	Target Neighborhood Hits	173	Shared Neighborhood Hits	49
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNG3_HUMAN
NC score	0.107983 (rank : 59)	θ value	0.365318 (rank : 66)
Query Neighborhood Hits	148	Target Neighborhood Hits	91	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

PKDRE_HUMAN
NC score	0.107096 (rank : 60)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	148	Target Neighborhood Hits	64	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNG3_MOUSE
NC score	0.104662 (rank : 61)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	148	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

TPTE_HUMAN
NC score	0.100213 (rank : 62)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	148	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

KCNA1_MOUSE
NC score	0.083575 (rank : 63)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	148	Target Neighborhood Hits	103	Shared Neighborhood Hits	36
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

PKDRE_MOUSE
NC score	0.083504 (rank : 64)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	148	Target Neighborhood Hits	76	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

MCLN2_MOUSE
NC score	0.083502 (rank : 65)	θ value	0.0148317 (rank : 46)
Query Neighborhood Hits	148	Target Neighborhood Hits	31	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

KCNA1_HUMAN
NC score	0.081726 (rank : 66)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	148	Target Neighborhood Hits	104	Shared Neighborhood Hits	35
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNQ4_HUMAN
NC score	0.078626 (rank : 67)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	148	Target Neighborhood Hits	136	Shared Neighborhood Hits	34
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNA6_MOUSE
NC score	0.077984 (rank : 68)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	148	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNA2_MOUSE
NC score	0.075994 (rank : 69)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA2_HUMAN
NC score	0.075116 (rank : 70)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	148	Target Neighborhood Hits	101	Shared Neighborhood Hits	32
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA6_HUMAN
NC score	0.072451 (rank : 71)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	148	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNQ1_MOUSE
NC score	0.070952 (rank : 72)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	148	Target Neighborhood Hits	175	Shared Neighborhood Hits	34
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNG1_HUMAN
NC score	0.070017 (rank : 73)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	148	Target Neighborhood Hits	103	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNA5_MOUSE
NC score	0.069565 (rank : 74)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	148	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNG2_HUMAN
NC score	0.067485 (rank : 75)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	148	Target Neighborhood Hits	83	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNA3_HUMAN
NC score	0.066997 (rank : 76)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	148	Target Neighborhood Hits	101	Shared Neighborhood Hits	31
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
NC score	0.066022 (rank : 77)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	148	Target Neighborhood Hits	103	Shared Neighborhood Hits	29
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA5_HUMAN
NC score	0.063912 (rank : 78)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	148	Target Neighborhood Hits	124	Shared Neighborhood Hits	28
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNG4_HUMAN
NC score	0.062840 (rank : 79)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	148	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

TRPM8_MOUSE
NC score	0.062467 (rank : 80)	θ value	0.0330416 (rank : 49)
Query Neighborhood Hits	148	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

KCNQ5_HUMAN
NC score	0.062011 (rank : 81)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	148	Target Neighborhood Hits	163	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNQ1_HUMAN
NC score	0.059175 (rank : 82)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	148	Target Neighborhood Hits	99	Shared Neighborhood Hits	29
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

TRPM8_HUMAN
NC score	0.056794 (rank : 83)	θ value	0.0961366 (rank : 52)
Query Neighborhood Hits	148	Target Neighborhood Hits	65	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

NPBL_MOUSE
NC score	0.056572 (rank : 84)	θ value	0.21417 (rank : 59)
Query Neighborhood Hits	148	Target Neighborhood Hits	1041	Shared Neighborhood Hits	41
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

KCNA4_MOUSE
NC score	0.056427 (rank : 85)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	148	Target Neighborhood Hits	98	Shared Neighborhood Hits	24
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA4_HUMAN
NC score	0.056075 (rank : 86)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	148	Target Neighborhood Hits	108	Shared Neighborhood Hits	24
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

TRPV3_HUMAN
NC score	0.054937 (rank : 87)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	148	Target Neighborhood Hits	198	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

KCNQ3_HUMAN
NC score	0.053167 (rank : 88)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	148	Target Neighborhood Hits	114	Shared Neighborhood Hits	30
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ2_HUMAN
NC score	0.051930 (rank : 89)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	148	Target Neighborhood Hits	114	Shared Neighborhood Hits	27
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ3_MOUSE
NC score	0.051915 (rank : 90)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	148	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

MCLN2_HUMAN
NC score	0.051661 (rank : 91)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	148	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IZK6, Q8N9R3	Gene names	MCOLN2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

NIPBL_HUMAN
NC score	0.049269 (rank : 92)	θ value	0.0193708 (rank : 48)
Query Neighborhood Hits	148	Target Neighborhood Hits	1311	Shared Neighborhood Hits	44
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

TRPC4_HUMAN
NC score	0.041955 (rank : 93)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	148	Target Neighborhood Hits	140	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
NC score	0.040476 (rank : 94)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	148	Target Neighborhood Hits	141	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

RBBP6_MOUSE
NC score	0.039715 (rank : 95)	θ value	0.21417 (rank : 60)
Query Neighborhood Hits	148	Target Neighborhood Hits	1014	Shared Neighborhood Hits	35
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TCP10_HUMAN
NC score	0.038979 (rank : 96)	θ value	0.813845 (rank : 75)
Query Neighborhood Hits	148	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

MCPH1_MOUSE
NC score	0.037723 (rank : 97)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	148	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

RBBP6_HUMAN
NC score	0.034331 (rank : 98)	θ value	0.0961366 (rank : 51)
Query Neighborhood Hits	148	Target Neighborhood Hits	1135	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

CENPC_MOUSE
NC score	0.034144 (rank : 99)	θ value	0.365318 (rank : 63)
Query Neighborhood Hits	148	Target Neighborhood Hits	154	Shared Neighborhood Hits	13
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

TGON2_HUMAN
NC score	0.032790 (rank : 100)	θ value	0.0148317 (rank : 47)
Query Neighborhood Hits	148	Target Neighborhood Hits	1037	Shared Neighborhood Hits	41
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

SRRM2_HUMAN
NC score	0.031368 (rank : 101)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	148	Target Neighborhood Hits	1296	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TTC16_HUMAN
NC score	0.027723 (rank : 102)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	148	Target Neighborhood Hits	417	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

DIDO1_HUMAN
NC score	0.027432 (rank : 103)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	148	Target Neighborhood Hits	960	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

TARA_HUMAN
NC score	0.026907 (rank : 104)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	148	Target Neighborhood Hits	1626	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TCF20_MOUSE
NC score	0.025021 (rank : 105)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	148	Target Neighborhood Hits	396	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

CASC3_MOUSE
NC score	0.024124 (rank : 106)	θ value	0.163984 (rank : 53)
Query Neighborhood Hits	148	Target Neighborhood Hits	333	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

ZN318_MOUSE
NC score	0.023327 (rank : 107)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	148	Target Neighborhood Hits	642	Shared Neighborhood Hits	23
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

PININ_HUMAN
NC score	0.021385 (rank : 108)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	148	Target Neighborhood Hits	753	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

TXND2_MOUSE
NC score	0.016951 (rank : 109)	θ value	0.21417 (rank : 61)
Query Neighborhood Hits	148	Target Neighborhood Hits	828	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

MLL2_HUMAN
NC score	0.016077 (rank : 110)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	148	Target Neighborhood Hits	1788	Shared Neighborhood Hits	38
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

RB15B_MOUSE
NC score	0.016045 (rank : 111)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	148	Target Neighborhood Hits	284	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PHZ5, Q8C6G2	Gene names	Rbm15b
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

MATR3_MOUSE
NC score	0.015735 (rank : 112)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	148	Target Neighborhood Hits	321	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

FA47A_HUMAN
NC score	0.015332 (rank : 113)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	148	Target Neighborhood Hits	451	Shared Neighborhood Hits	14
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

CD2_HUMAN
NC score	0.013389 (rank : 114)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	148	Target Neighborhood Hits	504	Shared Neighborhood Hits	16
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

PO6F2_HUMAN
NC score	0.013359 (rank : 115)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	148	Target Neighborhood Hits	618	Shared Neighborhood Hits	17
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

KI67_HUMAN
NC score	0.013247 (rank : 116)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	148	Target Neighborhood Hits	581	Shared Neighborhood Hits	21
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

MATR3_HUMAN
NC score	0.013243 (rank : 117)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	148	Target Neighborhood Hits	325	Shared Neighborhood Hits	10
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

PDZD2_HUMAN
NC score	0.011958 (rank : 118)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	148	Target Neighborhood Hits	772	Shared Neighborhood Hits	20
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

JPH2_HUMAN
NC score	0.010912 (rank : 119)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	148	Target Neighborhood Hits	639	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

TAF3_HUMAN
NC score	0.009888 (rank : 120)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	148	Target Neighborhood Hits	568	Shared Neighborhood Hits	24
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

RB15B_HUMAN
NC score	0.009620 (rank : 121)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	148	Target Neighborhood Hits	251	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NDT2, Q6QE19, Q9BV96	Gene names	RBM15B
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

TAIP2_HUMAN
NC score	0.009586 (rank : 122)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	148	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WYN3	Gene names	TAIP2
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 2 (TAIP-2).

NKTR_HUMAN
NC score	0.009330 (rank : 123)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	148	Target Neighborhood Hits	658	Shared Neighborhood Hits	28
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

DC1L2_MOUSE
NC score	0.009283 (rank : 124)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	148	Target Neighborhood Hits	173	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

CT128_HUMAN
NC score	0.009072 (rank : 125)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	148	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQN1, Q5JWN6, Q8N276	Gene names	C20orf128
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf128.

MBN3_MOUSE
NC score	0.008865 (rank : 126)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	148	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R003	Gene names	Mbnl3, Chcr, Mbxl
Domain Architecture	No domain graphic available
Description	Muscleblind-like X-linked protein (Muscleblind-like protein 3) (Cys3His CCG1-required protein) (Protein MCHCR).

EP300_HUMAN
NC score	0.008709 (rank : 127)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	148	Target Neighborhood Hits	821	Shared Neighborhood Hits	25
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

LMO7_HUMAN
NC score	0.008124 (rank : 128)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	148	Target Neighborhood Hits	507	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

TAIP2_MOUSE
NC score	0.007946 (rank : 129)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	148	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	P59055	Gene names	Taip2
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 2 (TAIP-2).

GPR63_MOUSE
NC score	0.007639 (rank : 130)	θ value	0.163984 (rank : 54)
Query Neighborhood Hits	148	Target Neighborhood Hits	774	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQQ3	Gene names	Gpr63
Domain Architecture
Description	Probable G-protein coupled receptor 63 (PSP24-beta) (PSP24-2).

TTC28_HUMAN
NC score	0.007638 (rank : 131)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	148	Target Neighborhood Hits	271	Shared Neighborhood Hits	13
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

TCRG1_HUMAN
NC score	0.006846 (rank : 132)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	148	Target Neighborhood Hits	929	Shared Neighborhood Hits	28
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

LSM11_MOUSE
NC score	0.006684 (rank : 133)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	148	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BUV6	Gene names	Lsm11
Domain Architecture	No domain graphic available
Description	U7 snRNA-associated Sm-like protein LSm11.

NEST_HUMAN
NC score	0.006614 (rank : 134)	θ value	0.279714 (rank : 62)
Query Neighborhood Hits	148	Target Neighborhood Hits	1305	Shared Neighborhood Hits	26
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

AK1A1_HUMAN
NC score	0.006563 (rank : 135)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	148	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	P14550	Gene names	AKR1A1, ALDR1, ALR
Domain Architecture
Description	Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde reductase) (Aldo- keto reductase family 1 member A1).

TSN17_MOUSE
NC score	0.006489 (rank : 136)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	148	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D7W4, Q91VI6	Gene names	Tspan17, Fbxo23, Tm4sf17
Domain Architecture	No domain graphic available
Description	Tetraspanin-17 (Tspan-17) (Transmembrane 4 superfamily member 17) (Tetraspan protein SB134) (F-box only protein 23).

DHX36_HUMAN
NC score	0.006374 (rank : 137)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	148	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

TSN17_HUMAN
NC score	0.006299 (rank : 138)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	148	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q96FV3, Q96S98, Q9UKB9	Gene names	TSPAN17, FBXO23, TM4SF17
Domain Architecture	No domain graphic available
Description	Tetraspanin-17 (Tspan-17) (Transmembrane 4 superfamily member 17) (Tetraspan protein SB134) (F-box only protein 23).

TTF2_MOUSE
NC score	0.006198 (rank : 139)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	148	Target Neighborhood Hits	364	Shared Neighborhood Hits	16
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

FAT2_HUMAN
NC score	0.005947 (rank : 140)	θ value	0.21417 (rank : 56)
Query Neighborhood Hits	148	Target Neighborhood Hits	507	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

DHX36_MOUSE
NC score	0.005912 (rank : 141)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	148	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

LIMA1_HUMAN
NC score	0.005686 (rank : 142)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	148	Target Neighborhood Hits	309	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

UBP28_MOUSE
NC score	0.005581 (rank : 143)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	148	Target Neighborhood Hits	178	Shared Neighborhood Hits	10
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

VN1B8_MOUSE
NC score	0.005376 (rank : 144)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	148	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQ45	Gene names	V1rb8, V1ra13
Domain Architecture	No domain graphic available
Description	Vomeronasal type-1 receptor B8 (Vomeronasal type-1 receptor A13).

TCRG1_MOUSE
NC score	0.005336 (rank : 145)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	148	Target Neighborhood Hits	947	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

GON4L_MOUSE
NC score	0.005277 (rank : 146)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	148	Target Neighborhood Hits	455	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

GPR63_HUMAN
NC score	0.005206 (rank : 147)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	148	Target Neighborhood Hits	776	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BZJ6, Q9UJH3	Gene names	GPR63, PSP24B
Domain Architecture
Description	Probable G-protein coupled receptor 63 (PSP24-beta) (PSP24-2).

TRI55_HUMAN
NC score	0.005083 (rank : 148)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	148	Target Neighborhood Hits	292	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

AK1A1_MOUSE
NC score	0.004947 (rank : 149)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	148	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JII6, Q9CQI5, Q9CQT8, Q9CT53, Q9D012, Q9D016, Q9D0I7, Q9D0P3	Gene names	Akr1a1, Akr1a4
Domain Architecture
Description	Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde reductase) (Aldo- keto reductase family 1 member A1).

UN45A_MOUSE
NC score	0.004740 (rank : 150)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	148	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q99KD5, Q3TKV6, Q8BFT3, Q8C157	Gene names	Unc45a, Smap1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Stromal membrane-associated protein 1) (Smap-1).

SPTN2_HUMAN
NC score	0.003979 (rank : 151)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	148	Target Neighborhood Hits	535	Shared Neighborhood Hits	10
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

SYTL2_HUMAN
NC score	0.003851 (rank : 152)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	148	Target Neighborhood Hits	248	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SPTB2_HUMAN
NC score	0.003556 (rank : 153)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	148	Target Neighborhood Hits	748	Shared Neighborhood Hits	17
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
NC score	0.003521 (rank : 154)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	148	Target Neighborhood Hits	770	Shared Neighborhood Hits	18
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

NCOR1_HUMAN
NC score	0.003478 (rank : 155)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	148	Target Neighborhood Hits	577	Shared Neighborhood Hits	18
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

FOXJ2_MOUSE
NC score	0.003103 (rank : 156)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	148	Target Neighborhood Hits	151	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ES18	Gene names	Foxj2, Fhx
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

IRF7_MOUSE
NC score	0.002979 (rank : 157)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	148	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

ARNT_MOUSE
NC score	0.002932 (rank : 158)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	148	Target Neighborhood Hits	213	Shared Neighborhood Hits	9
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

CD45_HUMAN
NC score	0.002533 (rank : 159)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	148	Target Neighborhood Hits	243	Shared Neighborhood Hits	9
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PDE3A_MOUSE
NC score	0.001624 (rank : 160)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	148	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

UBP6_HUMAN
NC score	0.001510 (rank : 161)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	148	Target Neighborhood Hits	188	Shared Neighborhood Hits	7
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

TUFT1_MOUSE
NC score	0.001501 (rank : 162)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	148	Target Neighborhood Hits	732	Shared Neighborhood Hits	9
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

CT075_HUMAN
NC score	0.001335 (rank : 163)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	148	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

ITSN1_MOUSE
NC score	0.000716 (rank : 164)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	148	Target Neighborhood Hits	1669	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

TLR8_MOUSE
NC score	0.000471 (rank : 165)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	148	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	P58682, Q91XI7	Gene names	Tlr8
Domain Architecture
Description	Toll-like receptor 8 precursor.

ITSN1_HUMAN
NC score	0.000032 (rank : 166)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	148	Target Neighborhood Hits	1757	Shared Neighborhood Hits	27
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

IRAK1_HUMAN
NC score	-0.000324 (rank : 167)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	148	Target Neighborhood Hits	820	Shared Neighborhood Hits	6
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

CO4A2_HUMAN
NC score	-0.000393 (rank : 168)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	148	Target Neighborhood Hits	454	Shared Neighborhood Hits	9
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

PCDG5_HUMAN
NC score	-0.000663 (rank : 169)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	148	Target Neighborhood Hits	159	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5G8, Q9Y5D2	Gene names	PCDHGA5
Domain Architecture
Description	Protocadherin gamma A5 precursor (PCDH-gamma-A5).

WNK1_HUMAN
NC score	-0.001340 (rank : 170)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	148	Target Neighborhood Hits	1158	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

CDKL5_HUMAN
NC score	-0.002029 (rank : 171)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	148	Target Neighborhood Hits	967	Shared Neighborhood Hits	14
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

IKKE_MOUSE
NC score	-0.002541 (rank : 172)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	148	Target Neighborhood Hits	848	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0T8	Gene names	Ikbke, Ikke, Ikki
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

ULK2_MOUSE
NC score	-0.002824 (rank : 173)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	148	Target Neighborhood Hits	943	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

EVI1_HUMAN
NC score	-0.003713 (rank : 174)	θ value	0.813845 (rank : 73)
Query Neighborhood Hits	148	Target Neighborhood Hits	924	Shared Neighborhood Hits	7
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.