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Network neighborhood for query Sequence : AK1A1_MOUSE

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AK1A1_MOUSE
 
SwissProt Accessions Q9JII6, Q9CQI5, Q9CQT8, Q9CT53, Q9D012, Q9D016, Q9D0I7, Q9D0P3 Gene names Akr1a1, Akr1a4
Domain
Architecture
Description Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde reductase) (Aldo- keto reductase family 1 member A1).
Rank Plots


Hits sorted by θ


AK1A1_MOUSE
 
θ value 1.36195e-181 (rank : 1) NC score 0.999962 (rank : 1)
Query Neighborhood Hits 29 Target Neighborhood Hits 29 Shared Neighborhood Hits 29
SwissProt Accessions Q9JII6, Q9CQI5, Q9CQT8, Q9CT53, Q9D012, Q9D016, Q9D0I7, Q9D0P3 Gene names Akr1a1, Akr1a4
Domain
Architecture
Description Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde reductase) (Aldo- keto reductase family 1 member A1).
AK1A1_HUMAN
 
θ value 3.14709e-170 (rank : 2) NC score 0.999635 (rank : 2)
Query Neighborhood Hits 29 Target Neighborhood Hits 29 Shared Neighborhood Hits 29
SwissProt Accessions P14550 Gene names AKR1A1, ALDR1, ALR
Domain
Architecture
Description Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde reductase) (Aldo- keto reductase family 1 member A1).
AK1BA_HUMAN
 
θ value 2.5521e-87 (rank : 3) NC score 0.980459 (rank : 7)
Query Neighborhood Hits 29 Target Neighborhood Hits 20 Shared Neighborhood Hits 20
SwissProt Accessions O60218, O75890 Gene names AKR1B10
Domain
Architecture
Description Aldo-keto reductase family 1 member B10 (EC 1.1.1.-) (Aldose reductase-like) (ARL-1) (Small intestine reductase) (SI reductase) (Aldose reductase-related protein) (ARP) (hARP).
ALD2_MOUSE
 
θ value 2.91998e-83 (rank : 4) NC score 0.979729 (rank : 8)
Query Neighborhood Hits 29 Target Neighborhood Hits 21 Shared Neighborhood Hits 17
SwissProt Accessions P45377, Q99JN4 Gene names Akr1b8, Fgfrp
Domain
Architecture
Description Aldose reductase-related protein 2 (EC 1.1.1.21) (AR) (Aldehyde reductase) (Fibroblast growth factor-regulated protein) (FR-1 protein).
ALDR_MOUSE
 
θ value 2.47191e-82 (rank : 5) NC score 0.987046 (rank : 3)
Query Neighborhood Hits 29 Target Neighborhood Hits 25 Shared Neighborhood Hits 22
SwissProt Accessions P45376, O70130, Q99KC9 Gene names Akr1b1, Akr1b3, Aldor1, Aldr1
Domain
Architecture
Description Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase).
ALDR_HUMAN
 
θ value 7.19216e-82 (rank : 6) NC score 0.985915 (rank : 5)
Query Neighborhood Hits 29 Target Neighborhood Hits 26 Shared Neighborhood Hits 22
SwissProt Accessions P15121, Q9BS21, Q9UCI9 Gene names AKR1B1, ALDR1
Domain
Architecture
Description Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase).
ALD1_MOUSE
 
θ value 2.31364e-80 (rank : 7) NC score 0.984850 (rank : 6)
Query Neighborhood Hits 29 Target Neighborhood Hits 22 Shared Neighborhood Hits 21
SwissProt Accessions P21300 Gene names Akr1b7, Avdp
Domain
Architecture
Description Aldose reductase-related protein 1 (EC 1.1.1.21) (AR) (Aldehyde reductase) (VAS deferens androgen-dependent protein) (MVDP) (Aldo-keto reductase family 1 member B7).
AK1D1_MOUSE
 
θ value 3.45727e-76 (rank : 8) NC score 0.976461 (rank : 13)
Query Neighborhood Hits 29 Target Neighborhood Hits 21 Shared Neighborhood Hits 19
SwissProt Accessions Q8VCX1 Gene names Akr1d1
Domain
Architecture

No domain graphic available

Description 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6) (Delta(4)-3- ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1).
AK1E1_MOUSE
 
θ value 4.51533e-76 (rank : 9) NC score 0.986095 (rank : 4)
Query Neighborhood Hits 29 Target Neighborhood Hits 26 Shared Neighborhood Hits 23
SwissProt Accessions Q9DCT1, O09125 Gene names Akr1e1
Domain
Architecture
Description Aldo-keto reductase family 1 member E1 (EC 1.1.1.-).
AK1C4_HUMAN
 
θ value 2.09745e-73 (rank : 10) NC score 0.975371 (rank : 16)
Query Neighborhood Hits 29 Target Neighborhood Hits 28 Shared Neighborhood Hits 24
SwissProt Accessions P17516, Q5T6A3, Q8WW84, Q9NS54 Gene names AKR1C4, CHDR
Domain
Architecture
Description Aldo-keto reductase family 1 member C4 (EC 1.1.1.-) (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (HAKRA).
AK1C1_HUMAN
 
θ value 3.57772e-73 (rank : 11) NC score 0.976558 (rank : 12)
Query Neighborhood Hits 29 Target Neighborhood Hits 29 Shared Neighborhood Hits 25
SwissProt Accessions Q04828, P52896, Q5SR15, Q9UCX2 Gene names AKR1C1, DDH, DDH1
Domain
Architecture
Description Aldo-keto reductase family 1 member C1 (EC 1.1.1.-) (20-alpha- hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Trans- 1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (High- affinity hepatic bile acid-binding protein) (HBAB) (Chlordecone reductase homolog HAKRC) (Dihydrodiol dehydrogenase 1/2) (DD1/DD2).
AK1C2_HUMAN
 
θ value 3.57772e-73 (rank : 12) NC score 0.977924 (rank : 10)
Query Neighborhood Hits 29 Target Neighborhood Hits 28 Shared Neighborhood Hits 25
SwissProt Accessions P52895, Q14133, Q96A71 Gene names AKR1C2, DDH2
Domain
Architecture
Description Aldo-keto reductase family 1 member C2 (EC 1.-.-.-) (Trans-1,2- dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (Type III 3- alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.213) (3-alpha-HSD3) (Chlordecone reductase homolog HAKRD) (Dihydrodiol dehydrogenase/bile acid-binding protein) (DD/BABP) (Dihydrodiol dehydrogenase 2) (DD2).
AK1D1_HUMAN
 
θ value 8.81223e-72 (rank : 13) NC score 0.977009 (rank : 11)
Query Neighborhood Hits 29 Target Neighborhood Hits 29 Shared Neighborhood Hits 22
SwissProt Accessions P51857 Gene names AKR1D1, SRD5B1
Domain
Architecture
Description 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1).
AK1C3_HUMAN
 
θ value 4.09345e-69 (rank : 14) NC score 0.975696 (rank : 14)
Query Neighborhood Hits 29 Target Neighborhood Hits 30 Shared Neighborhood Hits 25
SwissProt Accessions P42330, Q5T2L1, Q96DJ1, Q96KI8, Q99530, Q9UCX1, Q9UII3, Q9UKL9 Gene names AKR1C3, DDH1, KIAA0119, PGFS
Domain
Architecture
Description Aldo-keto reductase family 1 member C3 (EC 1.-.-.-) (Trans-1,2- dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (3-alpha- hydroxysteroid dehydrogenase type 2) (EC 1.1.1.213) (3-alpha-HSD type 2) (3-alpha-HSD type II, brain) (Prostaglandin F synthase) (EC 1.1.1.188) (PGFS) (Estradiol 17-beta-dehydrogenase) (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 5) (17-beta-HSD 5) (Chlordecone reductase homolog HAKRb) (HA1753) (Dihydrodiol dehydrogenase type I) (Dihydrodiol dehydrogenase 3) (DD3) (DD-3).
DHB5_MOUSE
 
θ value 9.11921e-69 (rank : 15) NC score 0.975672 (rank : 15)
Query Neighborhood Hits 29 Target Neighborhood Hits 26 Shared Neighborhood Hits 24
SwissProt Accessions P70694 Gene names Akr1c6, Hsd17b5
Domain
Architecture
Description Estradiol 17 beta-dehydrogenase 5 (EC 1.1.1.-) (17-beta-HSD 5).
AK1CD_MOUSE
 
θ value 1.71981e-67 (rank : 16) NC score 0.978549 (rank : 9)
Query Neighborhood Hits 29 Target Neighborhood Hits 33 Shared Neighborhood Hits 25
SwissProt Accessions Q8VC28, Q9D7R9, Q9R0M9 Gene names Akr1c13
Domain
Architecture
Description Aldo-keto reductase family 1 member C13 (EC 1.1.1.-).
AKC1H_MOUSE
 
θ value 2.74572e-65 (rank : 17) NC score 0.973619 (rank : 17)
Query Neighborhood Hits 29 Target Neighborhood Hits 22 Shared Neighborhood Hits 22
SwissProt Accessions Q8K023, Q99N44 Gene names Akr1c18
Domain
Architecture

No domain graphic available

Description Aldo-keto reductase family 1 member C18 (EC 1.1.-.-) (20-alpha- hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD).
KCAB2_MOUSE
 
θ value 2.21117e-06 (rank : 18) NC score 0.253417 (rank : 23)
Query Neighborhood Hits 29 Target Neighborhood Hits 22 Shared Neighborhood Hits 20
SwissProt Accessions P62482, P97381, Q60942, Q64284 Gene names Kcnab2, Ckbeta2, I2rf5, Kcnb3
Domain
Architecture
Description Voltage-gated potassium channel subunit beta-2 (K(+) channel subunit beta-2) (Kv-beta-2) (Neuroimmune protein F5).
KCAB1_HUMAN
 
θ value 8.40245e-06 (rank : 19) NC score 0.271226 (rank : 19)
Query Neighborhood Hits 29 Target Neighborhood Hits 29 Shared Neighborhood Hits 21
SwissProt Accessions Q14722, Q13031, Q13302, Q16547, Q99869 Gene names KCNAB1, KCNA1B
Domain
Architecture
Description Voltage-gated potassium channel subunit beta-1 (K(+) channel subunit beta-1) (Kv-beta-1).
KCAB1_MOUSE
 
θ value 8.40245e-06 (rank : 20) NC score 0.270848 (rank : 20)
Query Neighborhood Hits 29 Target Neighborhood Hits 27 Shared Neighborhood Hits 21
SwissProt Accessions P63143, P97380, Q61763, Q63277 Gene names Kcnab1, Kvb1
Domain
Architecture

No domain graphic available

Description Voltage-gated potassium channel subunit beta-1 (K(+) channel subunit beta-1) (Kv-beta-1).
KCAB2_HUMAN
 
θ value 8.40245e-06 (rank : 21) NC score 0.257686 (rank : 22)
Query Neighborhood Hits 29 Target Neighborhood Hits 24 Shared Neighborhood Hits 21
SwissProt Accessions Q13303, O43659, Q5TG82, Q5TG83, Q99411 Gene names KCNAB2, KCNA2B, KCNK2
Domain
Architecture
Description Voltage-gated potassium channel subunit beta-2 (K(+) channel subunit beta-2) (Kv-beta-2) (HKvbeta2).
ARK72_HUMAN
 
θ value 0.000602161 (rank : 22) NC score 0.266288 (rank : 21)
Query Neighborhood Hits 29 Target Neighborhood Hits 24 Shared Neighborhood Hits 19
SwissProt Accessions O43488, O75749, Q5TG63 Gene names AKR7A2, AFAR, AFAR1, AKR7
Domain
Architecture
Description Aflatoxin B1 aldehyde reductase member 2 (EC 1.-.-.-) (AFB1-AR 1) (Aldoketoreductase 7).
ARK72_MOUSE
 
θ value 0.000602161 (rank : 23) NC score 0.273520 (rank : 18)
Query Neighborhood Hits 29 Target Neighborhood Hits 24 Shared Neighborhood Hits 18
SwissProt Accessions Q8CG76, Q3UPU2, Q8CG77, Q8JZQ8, Q9D157 Gene names Akr7a2, Afar, Akr7a5
Domain
Architecture
Description Aflatoxin B1 aldehyde reductase member 2 (EC 1.-.-.-).
KCAB3_HUMAN
 
θ value 0.0431538 (rank : 24) NC score 0.162830 (rank : 25)
Query Neighborhood Hits 29 Target Neighborhood Hits 28 Shared Neighborhood Hits 15
SwissProt Accessions O43448 Gene names KCNAB3, KCNA3B
Domain
Architecture
Description Voltage-gated potassium channel subunit beta-3 (K(+) channel subunit beta-3) (Kv-beta-3).
ARK73_HUMAN
 
θ value 0.0736092 (rank : 25) NC score 0.249053 (rank : 24)
Query Neighborhood Hits 29 Target Neighborhood Hits 19 Shared Neighborhood Hits 17
SwissProt Accessions O95154, Q86SR4, Q8IVN6, Q8N5V6, Q8TAX1, Q9NUC3 Gene names AKR7A3, AFAR2
Domain
Architecture
Description Aflatoxin B1 aldehyde reductase member 3 (EC 1.-.-.-) (AFB1-AR 2).
GSH0_MOUSE
 
θ value 1.81305 (rank : 26) NC score 0.052927 (rank : 28)
Query Neighborhood Hits 29 Target Neighborhood Hits 16 Shared Neighborhood Hits 8
SwissProt Accessions O09172 Gene names Gclm, Glclr
Domain
Architecture
Description Glutamate--cysteine ligase regulatory subunit (EC 6.3.2.2) (Gamma- glutamylcysteine synthetase) (Gamma-ECS) (GCS light chain) (Glutamate--cysteine ligase modifier subunit).
GSH0_HUMAN
 
θ value 3.0926 (rank : 27) NC score 0.054947 (rank : 27)
Query Neighborhood Hits 29 Target Neighborhood Hits 14 Shared Neighborhood Hits 9
SwissProt Accessions P48507, Q6FHC1, Q9NPX9, Q9NU74 Gene names GCLM, GLCLR
Domain
Architecture
Description Glutamate--cysteine ligase regulatory subunit (EC 6.3.2.2) (Gamma- glutamylcysteine synthetase) (Gamma-ECS) (GCS light chain) (Glutamate--cysteine ligase modifier subunit).
CAC1E_HUMAN
 
θ value 8.99809 (rank : 28) NC score 0.004947 (rank : 29)
Query Neighborhood Hits 29 Target Neighborhood Hits 148 Shared Neighborhood Hits 4
SwissProt Accessions Q15878, Q14580, Q14581 Gene names CACNA1E, CACH6, CACNL1A6
Domain
Architecture
Description Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).
CAC1E_MOUSE
 
θ value 8.99809 (rank : 29) NC score 0.004927 (rank : 30)
Query Neighborhood Hits 29 Target Neighborhood Hits 167 Shared Neighborhood Hits 4
SwissProt Accessions Q61290 Gene names Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain
Architecture
Description Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).
KCAB3_MOUSE
 
θ value θ > 10 (rank : 30) NC score 0.116640 (rank : 26)
Query Neighborhood Hits 29 Target Neighborhood Hits 16 Shared Neighborhood Hits 9
SwissProt Accessions P97382 Gene names Kcnab3
Domain
Architecture
Description Voltage-gated potassium channel subunit beta-3 (K(+) channel subunit beta-3) (Kv-beta-3).

Hits sorted by NC score


AK1A1_MOUSE
 
NC score 0.999962 (rank : 1) θ value 1.36195e-181 (rank : 1)
Query Neighborhood Hits 29 Target Neighborhood Hits 29 Shared Neighborhood Hits 29
SwissProt Accessions Q9JII6, Q9CQI5, Q9CQT8, Q9CT53, Q9D012, Q9D016, Q9D0I7, Q9D0P3 Gene names Akr1a1, Akr1a4
Domain
Architecture
Description Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde reductase) (Aldo- keto reductase family 1 member A1).
AK1A1_HUMAN
 
NC score 0.999635 (rank : 2) θ value 3.14709e-170 (rank : 2)
Query Neighborhood Hits 29 Target Neighborhood Hits 29 Shared Neighborhood Hits 29
SwissProt Accessions P14550 Gene names AKR1A1, ALDR1, ALR
Domain
Architecture
Description Alcohol dehydrogenase [NADP+] (EC 1.1.1.2) (Aldehyde reductase) (Aldo- keto reductase family 1 member A1).
ALDR_MOUSE
 
NC score 0.987046 (rank : 3) θ value 2.47191e-82 (rank : 5)
Query Neighborhood Hits 29 Target Neighborhood Hits 25 Shared Neighborhood Hits 22
SwissProt Accessions P45376, O70130, Q99KC9 Gene names Akr1b1, Akr1b3, Aldor1, Aldr1
Domain
Architecture
Description Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase).
AK1E1_MOUSE
 
NC score 0.986095 (rank : 4) θ value 4.51533e-76 (rank : 9)
Query Neighborhood Hits 29 Target Neighborhood Hits 26 Shared Neighborhood Hits 23
SwissProt Accessions Q9DCT1, O09125 Gene names Akr1e1
Domain
Architecture
Description Aldo-keto reductase family 1 member E1 (EC 1.1.1.-).
ALDR_HUMAN
 
NC score 0.985915 (rank : 5) θ value 7.19216e-82 (rank : 6)
Query Neighborhood Hits 29 Target Neighborhood Hits 26 Shared Neighborhood Hits 22
SwissProt Accessions P15121, Q9BS21, Q9UCI9 Gene names AKR1B1, ALDR1
Domain
Architecture
Description Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase).
ALD1_MOUSE
 
NC score 0.984850 (rank : 6) θ value 2.31364e-80 (rank : 7)
Query Neighborhood Hits 29 Target Neighborhood Hits 22 Shared Neighborhood Hits 21
SwissProt Accessions P21300 Gene names Akr1b7, Avdp
Domain
Architecture
Description Aldose reductase-related protein 1 (EC 1.1.1.21) (AR) (Aldehyde reductase) (VAS deferens androgen-dependent protein) (MVDP) (Aldo-keto reductase family 1 member B7).
AK1BA_HUMAN
 
NC score 0.980459 (rank : 7) θ value 2.5521e-87 (rank : 3)
Query Neighborhood Hits 29 Target Neighborhood Hits 20 Shared Neighborhood Hits 20
SwissProt Accessions O60218, O75890 Gene names AKR1B10
Domain
Architecture
Description Aldo-keto reductase family 1 member B10 (EC 1.1.1.-) (Aldose reductase-like) (ARL-1) (Small intestine reductase) (SI reductase) (Aldose reductase-related protein) (ARP) (hARP).
ALD2_MOUSE
 
NC score 0.979729 (rank : 8) θ value 2.91998e-83 (rank : 4)
Query Neighborhood Hits 29 Target Neighborhood Hits 21 Shared Neighborhood Hits 17
SwissProt Accessions P45377, Q99JN4 Gene names Akr1b8, Fgfrp
Domain
Architecture
Description Aldose reductase-related protein 2 (EC 1.1.1.21) (AR) (Aldehyde reductase) (Fibroblast growth factor-regulated protein) (FR-1 protein).
AK1CD_MOUSE
 
NC score 0.978549 (rank : 9) θ value 1.71981e-67 (rank : 16)
Query Neighborhood Hits 29 Target Neighborhood Hits 33 Shared Neighborhood Hits 25
SwissProt Accessions Q8VC28, Q9D7R9, Q9R0M9 Gene names Akr1c13
Domain
Architecture
Description Aldo-keto reductase family 1 member C13 (EC 1.1.1.-).
AK1C2_HUMAN
 
NC score 0.977924 (rank : 10) θ value 3.57772e-73 (rank : 12)
Query Neighborhood Hits 29 Target Neighborhood Hits 28 Shared Neighborhood Hits 25
SwissProt Accessions P52895, Q14133, Q96A71 Gene names AKR1C2, DDH2
Domain
Architecture
Description Aldo-keto reductase family 1 member C2 (EC 1.-.-.-) (Trans-1,2- dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (Type III 3- alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.213) (3-alpha-HSD3) (Chlordecone reductase homolog HAKRD) (Dihydrodiol dehydrogenase/bile acid-binding protein) (DD/BABP) (Dihydrodiol dehydrogenase 2) (DD2).
AK1D1_HUMAN
 
NC score 0.977009 (rank : 11) θ value 8.81223e-72 (rank : 13)
Query Neighborhood Hits 29 Target Neighborhood Hits 29 Shared Neighborhood Hits 22
SwissProt Accessions P51857 Gene names AKR1D1, SRD5B1
Domain
Architecture
Description 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1).
AK1C1_HUMAN
 
NC score 0.976558 (rank : 12) θ value 3.57772e-73 (rank : 11)
Query Neighborhood Hits 29 Target Neighborhood Hits 29 Shared Neighborhood Hits 25
SwissProt Accessions Q04828, P52896, Q5SR15, Q9UCX2 Gene names AKR1C1, DDH, DDH1
Domain
Architecture
Description Aldo-keto reductase family 1 member C1 (EC 1.1.1.-) (20-alpha- hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD) (Trans- 1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (High- affinity hepatic bile acid-binding protein) (HBAB) (Chlordecone reductase homolog HAKRC) (Dihydrodiol dehydrogenase 1/2) (DD1/DD2).
AK1D1_MOUSE
 
NC score 0.976461 (rank : 13) θ value 3.45727e-76 (rank : 8)
Query Neighborhood Hits 29 Target Neighborhood Hits 21 Shared Neighborhood Hits 19
SwissProt Accessions Q8VCX1 Gene names Akr1d1
Domain
Architecture

No domain graphic available

Description 3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.99.6) (Delta(4)-3- ketosteroid 5-beta-reductase) (Aldo-keto reductase family 1 member D1).
AK1C3_HUMAN
 
NC score 0.975696 (rank : 14) θ value 4.09345e-69 (rank : 14)
Query Neighborhood Hits 29 Target Neighborhood Hits 30 Shared Neighborhood Hits 25
SwissProt Accessions P42330, Q5T2L1, Q96DJ1, Q96KI8, Q99530, Q9UCX1, Q9UII3, Q9UKL9 Gene names AKR1C3, DDH1, KIAA0119, PGFS
Domain
Architecture
Description Aldo-keto reductase family 1 member C3 (EC 1.-.-.-) (Trans-1,2- dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20) (3-alpha- hydroxysteroid dehydrogenase type 2) (EC 1.1.1.213) (3-alpha-HSD type 2) (3-alpha-HSD type II, brain) (Prostaglandin F synthase) (EC 1.1.1.188) (PGFS) (Estradiol 17-beta-dehydrogenase) (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 5) (17-beta-HSD 5) (Chlordecone reductase homolog HAKRb) (HA1753) (Dihydrodiol dehydrogenase type I) (Dihydrodiol dehydrogenase 3) (DD3) (DD-3).
DHB5_MOUSE
 
NC score 0.975672 (rank : 15) θ value 9.11921e-69 (rank : 15)
Query Neighborhood Hits 29 Target Neighborhood Hits 26 Shared Neighborhood Hits 24
SwissProt Accessions P70694 Gene names Akr1c6, Hsd17b5
Domain
Architecture
Description Estradiol 17 beta-dehydrogenase 5 (EC 1.1.1.-) (17-beta-HSD 5).
AK1C4_HUMAN
 
NC score 0.975371 (rank : 16) θ value 2.09745e-73 (rank : 10)
Query Neighborhood Hits 29 Target Neighborhood Hits 28 Shared Neighborhood Hits 24
SwissProt Accessions P17516, Q5T6A3, Q8WW84, Q9NS54 Gene names AKR1C4, CHDR
Domain
Architecture
Description Aldo-keto reductase family 1 member C4 (EC 1.1.1.-) (Chlordecone reductase) (EC 1.1.1.225) (CDR) (3-alpha-hydroxysteroid dehydrogenase type I) (EC 1.1.1.50) (3-alpha-HSD1) (Dihydrodiol dehydrogenase 4) (DD4) (HAKRA).
AKC1H_MOUSE
 
NC score 0.973619 (rank : 17) θ value 2.74572e-65 (rank : 17)
Query Neighborhood Hits 29 Target Neighborhood Hits 22 Shared Neighborhood Hits 22
SwissProt Accessions Q8K023, Q99N44 Gene names Akr1c18
Domain
Architecture

No domain graphic available

Description Aldo-keto reductase family 1 member C18 (EC 1.1.-.-) (20-alpha- hydroxysteroid dehydrogenase) (EC 1.1.1.149) (20-alpha-HSD).
ARK72_MOUSE
 
NC score 0.273520 (rank : 18) θ value 0.000602161 (rank : 23)
Query Neighborhood Hits 29 Target Neighborhood Hits 24 Shared Neighborhood Hits 18
SwissProt Accessions Q8CG76, Q3UPU2, Q8CG77, Q8JZQ8, Q9D157 Gene names Akr7a2, Afar, Akr7a5
Domain
Architecture
Description Aflatoxin B1 aldehyde reductase member 2 (EC 1.-.-.-).
KCAB1_HUMAN
 
NC score 0.271226 (rank : 19) θ value 8.40245e-06 (rank : 19)
Query Neighborhood Hits 29 Target Neighborhood Hits 29 Shared Neighborhood Hits 21
SwissProt Accessions Q14722, Q13031, Q13302, Q16547, Q99869 Gene names KCNAB1, KCNA1B
Domain
Architecture
Description Voltage-gated potassium channel subunit beta-1 (K(+) channel subunit beta-1) (Kv-beta-1).
KCAB1_MOUSE
 
NC score 0.270848 (rank : 20) θ value 8.40245e-06 (rank : 20)
Query Neighborhood Hits 29 Target Neighborhood Hits 27 Shared Neighborhood Hits 21
SwissProt Accessions P63143, P97380, Q61763, Q63277 Gene names Kcnab1, Kvb1
Domain
Architecture

No domain graphic available

Description Voltage-gated potassium channel subunit beta-1 (K(+) channel subunit beta-1) (Kv-beta-1).
ARK72_HUMAN
 
NC score 0.266288 (rank : 21) θ value 0.000602161 (rank : 22)
Query Neighborhood Hits 29 Target Neighborhood Hits 24 Shared Neighborhood Hits 19
SwissProt Accessions O43488, O75749, Q5TG63 Gene names AKR7A2, AFAR, AFAR1, AKR7
Domain
Architecture
Description Aflatoxin B1 aldehyde reductase member 2 (EC 1.-.-.-) (AFB1-AR 1) (Aldoketoreductase 7).
KCAB2_HUMAN
 
NC score 0.257686 (rank : 22) θ value 8.40245e-06 (rank : 21)
Query Neighborhood Hits 29 Target Neighborhood Hits 24 Shared Neighborhood Hits 21
SwissProt Accessions Q13303, O43659, Q5TG82, Q5TG83, Q99411 Gene names KCNAB2, KCNA2B, KCNK2
Domain
Architecture
Description Voltage-gated potassium channel subunit beta-2 (K(+) channel subunit beta-2) (Kv-beta-2) (HKvbeta2).
KCAB2_MOUSE
 
NC score 0.253417 (rank : 23) θ value 2.21117e-06 (rank : 18)
Query Neighborhood Hits 29 Target Neighborhood Hits 22 Shared Neighborhood Hits 20
SwissProt Accessions P62482, P97381, Q60942, Q64284 Gene names Kcnab2, Ckbeta2, I2rf5, Kcnb3
Domain
Architecture
Description Voltage-gated potassium channel subunit beta-2 (K(+) channel subunit beta-2) (Kv-beta-2) (Neuroimmune protein F5).
ARK73_HUMAN
 
NC score 0.249053 (rank : 24) θ value 0.0736092 (rank : 25)
Query Neighborhood Hits 29 Target Neighborhood Hits 19 Shared Neighborhood Hits 17
SwissProt Accessions O95154, Q86SR4, Q8IVN6, Q8N5V6, Q8TAX1, Q9NUC3 Gene names AKR7A3, AFAR2
Domain
Architecture
Description Aflatoxin B1 aldehyde reductase member 3 (EC 1.-.-.-) (AFB1-AR 2).
KCAB3_HUMAN
 
NC score 0.162830 (rank : 25) θ value 0.0431538 (rank : 24)
Query Neighborhood Hits 29 Target Neighborhood Hits 28 Shared Neighborhood Hits 15
SwissProt Accessions O43448 Gene names KCNAB3, KCNA3B
Domain
Architecture
Description Voltage-gated potassium channel subunit beta-3 (K(+) channel subunit beta-3) (Kv-beta-3).
KCAB3_MOUSE
 
NC score 0.116640 (rank : 26) θ value θ > 10 (rank : 30)
Query Neighborhood Hits 29 Target Neighborhood Hits 16 Shared Neighborhood Hits 9
SwissProt Accessions P97382 Gene names Kcnab3
Domain
Architecture
Description Voltage-gated potassium channel subunit beta-3 (K(+) channel subunit beta-3) (Kv-beta-3).
GSH0_HUMAN
 
NC score 0.054947 (rank : 27) θ value 3.0926 (rank : 27)
Query Neighborhood Hits 29 Target Neighborhood Hits 14 Shared Neighborhood Hits 9
SwissProt Accessions P48507, Q6FHC1, Q9NPX9, Q9NU74 Gene names GCLM, GLCLR
Domain
Architecture
Description Glutamate--cysteine ligase regulatory subunit (EC 6.3.2.2) (Gamma- glutamylcysteine synthetase) (Gamma-ECS) (GCS light chain) (Glutamate--cysteine ligase modifier subunit).
GSH0_MOUSE
 
NC score 0.052927 (rank : 28) θ value 1.81305 (rank : 26)
Query Neighborhood Hits 29 Target Neighborhood Hits 16 Shared Neighborhood Hits 8
SwissProt Accessions O09172 Gene names Gclm, Glclr
Domain
Architecture
Description Glutamate--cysteine ligase regulatory subunit (EC 6.3.2.2) (Gamma- glutamylcysteine synthetase) (Gamma-ECS) (GCS light chain) (Glutamate--cysteine ligase modifier subunit).
CAC1E_HUMAN
 
NC score 0.004947 (rank : 29) θ value 8.99809 (rank : 28)
Query Neighborhood Hits 29 Target Neighborhood Hits 148 Shared Neighborhood Hits 4
SwissProt Accessions Q15878, Q14580, Q14581 Gene names CACNA1E, CACH6, CACNL1A6
Domain
Architecture
Description Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).
CAC1E_MOUSE
 
NC score 0.004927 (rank : 30) θ value 8.99809 (rank : 29)
Query Neighborhood Hits 29 Target Neighborhood Hits 167 Shared Neighborhood Hits 4
SwissProt Accessions Q61290 Gene names Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain
Architecture
Description Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).