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Network neighborhood for query Sequence : CAC1C_MOUSE

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CAC1C_MOUSE
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAC1A_HUMAN
θ value	0 (rank : 1)	NC score	0.944698 (rank : 13)
Query Neighborhood Hits	130	Target Neighborhood Hits	387	Shared Neighborhood Hits	62
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_MOUSE
θ value	0 (rank : 2)	NC score	0.953425 (rank : 11)
Query Neighborhood Hits	130	Target Neighborhood Hits	267	Shared Neighborhood Hits	63
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_HUMAN
θ value	0 (rank : 3)	NC score	0.954697 (rank : 10)
Query Neighborhood Hits	130	Target Neighborhood Hits	257	Shared Neighborhood Hits	58
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1B_MOUSE
θ value	0 (rank : 4)	NC score	0.949188 (rank : 12)
Query Neighborhood Hits	130	Target Neighborhood Hits	351	Shared Neighborhood Hits	57
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1C_HUMAN
θ value	0 (rank : 5)	NC score	0.997417 (rank : 2)
Query Neighborhood Hits	130	Target Neighborhood Hits	158	Shared Neighborhood Hits	97
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1C_MOUSE
θ value	0 (rank : 6)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	130	Target Neighborhood Hits	130	Shared Neighborhood Hits	130
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1D_HUMAN
θ value	0 (rank : 7)	NC score	0.994293 (rank : 4)
Query Neighborhood Hits	130	Target Neighborhood Hits	118	Shared Neighborhood Hits	60
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1E_HUMAN
θ value	0 (rank : 8)	NC score	0.958446 (rank : 9)
Query Neighborhood Hits	130	Target Neighborhood Hits	148	Shared Neighborhood Hits	57
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	0 (rank : 9)	NC score	0.958504 (rank : 8)
Query Neighborhood Hits	130	Target Neighborhood Hits	167	Shared Neighborhood Hits	59
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1F_HUMAN
θ value	0 (rank : 10)	NC score	0.991918 (rank : 7)
Query Neighborhood Hits	130	Target Neighborhood Hits	141	Shared Neighborhood Hits	61
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_MOUSE
θ value	0 (rank : 11)	NC score	0.992222 (rank : 6)
Query Neighborhood Hits	130	Target Neighborhood Hits	142	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1S_HUMAN
θ value	0 (rank : 12)	NC score	0.994515 (rank : 3)
Query Neighborhood Hits	130	Target Neighborhood Hits	92	Shared Neighborhood Hits	60
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1S_MOUSE
θ value	0 (rank : 13)	NC score	0.993423 (rank : 5)
Query Neighborhood Hits	130	Target Neighborhood Hits	98	Shared Neighborhood Hits	56
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SCN7A_HUMAN
θ value	5.67233e-95 (rank : 14)	NC score	0.851684 (rank : 19)
Query Neighborhood Hits	130	Target Neighborhood Hits	135	Shared Neighborhood Hits	50
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

CAC1I_HUMAN
θ value	7.20884e-74 (rank : 15)	NC score	0.894870 (rank : 14)
Query Neighborhood Hits	130	Target Neighborhood Hits	138	Shared Neighborhood Hits	56
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

SC11A_HUMAN
θ value	3.02872e-72 (rank : 16)	NC score	0.856068 (rank : 18)
Query Neighborhood Hits	130	Target Neighborhood Hits	111	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SCN3A_HUMAN
θ value	6.31527e-70 (rank : 17)	NC score	0.842073 (rank : 23)
Query Neighborhood Hits	130	Target Neighborhood Hits	115	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN2A_HUMAN
θ value	8.24801e-70 (rank : 18)	NC score	0.839339 (rank : 25)
Query Neighborhood Hits	130	Target Neighborhood Hits	157	Shared Neighborhood Hits	60
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN4A_HUMAN
θ value	1.83746e-69 (rank : 19)	NC score	0.848654 (rank : 22)
Query Neighborhood Hits	130	Target Neighborhood Hits	133	Shared Neighborhood Hits	60
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN9A_HUMAN
θ value	3.4653e-68 (rank : 20)	NC score	0.838679 (rank : 26)
Query Neighborhood Hits	130	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

CAC1H_HUMAN
θ value	1.6097e-65 (rank : 21)	NC score	0.865666 (rank : 16)
Query Neighborhood Hits	130	Target Neighborhood Hits	307	Shared Neighborhood Hits	60
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

SCN5A_HUMAN
θ value	2.74572e-65 (rank : 22)	NC score	0.850197 (rank : 21)
Query Neighborhood Hits	130	Target Neighborhood Hits	145	Shared Neighborhood Hits	58
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SCN1A_HUMAN
θ value	1.36269e-64 (rank : 23)	NC score	0.836675 (rank : 28)
Query Neighborhood Hits	130	Target Neighborhood Hits	148	Shared Neighborhood Hits	59
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

CAC1G_HUMAN
θ value	2.32439e-64 (rank : 24)	NC score	0.850315 (rank : 20)
Query Neighborhood Hits	130	Target Neighborhood Hits	587	Shared Neighborhood Hits	60
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SC10A_MOUSE
θ value	2.32439e-64 (rank : 25)	NC score	0.839518 (rank : 24)
Query Neighborhood Hits	130	Target Neighborhood Hits	107	Shared Neighborhood Hits	60
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

CAC1H_MOUSE
θ value	6.76295e-64 (rank : 26)	NC score	0.868803 (rank : 15)
Query Neighborhood Hits	130	Target Neighborhood Hits	230	Shared Neighborhood Hits	58
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

SC10A_HUMAN
θ value	1.50663e-63 (rank : 27)	NC score	0.835347 (rank : 29)
Query Neighborhood Hits	130	Target Neighborhood Hits	116	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SC11A_MOUSE
θ value	5.7252e-63 (rank : 28)	NC score	0.857583 (rank : 17)
Query Neighborhood Hits	130	Target Neighborhood Hits	116	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SCN8A_HUMAN
θ value	8.26713e-62 (rank : 29)	NC score	0.837505 (rank : 27)
Query Neighborhood Hits	130	Target Neighborhood Hits	135	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
θ value	1.84173e-61 (rank : 30)	NC score	0.834911 (rank : 30)
Query Neighborhood Hits	130	Target Neighborhood Hits	136	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

PK2L2_HUMAN
θ value	1.38499e-08 (rank : 31)	NC score	0.390830 (rank : 31)
Query Neighborhood Hits	130	Target Neighborhood Hits	90	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L2_MOUSE
θ value	1.99992e-07 (rank : 32)	NC score	0.354284 (rank : 33)
Query Neighborhood Hits	130	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

KCNB2_HUMAN
θ value	4.45536e-07 (rank : 33)	NC score	0.216935 (rank : 38)
Query Neighborhood Hits	130	Target Neighborhood Hits	212	Shared Neighborhood Hits	59
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

PKD2_HUMAN
θ value	4.45536e-07 (rank : 34)	NC score	0.337490 (rank : 35)
Query Neighborhood Hits	130	Target Neighborhood Hits	105	Shared Neighborhood Hits	35
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCNB1_HUMAN
θ value	5.81887e-07 (rank : 35)	NC score	0.204607 (rank : 40)
Query Neighborhood Hits	130	Target Neighborhood Hits	169	Shared Neighborhood Hits	55
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	5.81887e-07 (rank : 36)	NC score	0.204507 (rank : 41)
Query Neighborhood Hits	130	Target Neighborhood Hits	154	Shared Neighborhood Hits	54
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

PK2L1_HUMAN
θ value	9.92553e-07 (rank : 37)	NC score	0.357536 (rank : 32)
Query Neighborhood Hits	130	Target Neighborhood Hits	132	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PKD2_MOUSE
θ value	6.43352e-06 (rank : 38)	NC score	0.342962 (rank : 34)
Query Neighborhood Hits	130	Target Neighborhood Hits	99	Shared Neighborhood Hits	37
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

KCNF1_HUMAN
θ value	2.44474e-05 (rank : 39)	NC score	0.244528 (rank : 36)
Query Neighborhood Hits	130	Target Neighborhood Hits	109	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNV2_HUMAN
θ value	9.29e-05 (rank : 40)	NC score	0.231777 (rank : 37)
Query Neighborhood Hits	130	Target Neighborhood Hits	137	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNS3_HUMAN
θ value	0.00175202 (rank : 41)	NC score	0.180676 (rank : 44)
Query Neighborhood Hits	130	Target Neighborhood Hits	125	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCNS1_MOUSE
θ value	0.00509761 (rank : 42)	NC score	0.143524 (rank : 51)
Query Neighborhood Hits	130	Target Neighborhood Hits	114	Shared Neighborhood Hits	46
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCND1_MOUSE
θ value	0.00665767 (rank : 43)	NC score	0.165070 (rank : 48)
Query Neighborhood Hits	130	Target Neighborhood Hits	165	Shared Neighborhood Hits	52
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNS2_HUMAN
θ value	0.0113563 (rank : 44)	NC score	0.202149 (rank : 42)
Query Neighborhood Hits	130	Target Neighborhood Hits	129	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNQ4_HUMAN
θ value	0.0252991 (rank : 45)	NC score	0.096891 (rank : 62)
Query Neighborhood Hits	130	Target Neighborhood Hits	136	Shared Neighborhood Hits	35
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCND3_HUMAN
θ value	0.0330416 (rank : 46)	NC score	0.180626 (rank : 45)
Query Neighborhood Hits	130	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	0.0330416 (rank : 47)	NC score	0.180783 (rank : 43)
Query Neighborhood Hits	130	Target Neighborhood Hits	162	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNS2_MOUSE
θ value	0.0330416 (rank : 48)	NC score	0.205577 (rank : 39)
Query Neighborhood Hits	130	Target Neighborhood Hits	130	Shared Neighborhood Hits	54
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

NIPBL_HUMAN
θ value	0.0330416 (rank : 49)	NC score	0.037924 (rank : 90)
Query Neighborhood Hits	130	Target Neighborhood Hits	1311	Shared Neighborhood Hits	36
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

KCNQ2_HUMAN
θ value	0.0431538 (rank : 50)	NC score	0.069392 (rank : 78)
Query Neighborhood Hits	130	Target Neighborhood Hits	114	Shared Neighborhood Hits	28
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
θ value	0.0431538 (rank : 51)	NC score	0.065404 (rank : 82)
Query Neighborhood Hits	130	Target Neighborhood Hits	163	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNS1_HUMAN
θ value	0.0431538 (rank : 52)	NC score	0.154080 (rank : 50)
Query Neighborhood Hits	130	Target Neighborhood Hits	116	Shared Neighborhood Hits	52
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCND1_HUMAN
θ value	0.0563607 (rank : 53)	NC score	0.160719 (rank : 49)
Query Neighborhood Hits	130	Target Neighborhood Hits	160	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND2_HUMAN
θ value	0.0563607 (rank : 54)	NC score	0.174288 (rank : 47)
Query Neighborhood Hits	130	Target Neighborhood Hits	154	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	0.0563607 (rank : 55)	NC score	0.174442 (rank : 46)
Query Neighborhood Hits	130	Target Neighborhood Hits	156	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

PKDRE_HUMAN
θ value	0.163984 (rank : 56)	NC score	0.107530 (rank : 59)
Query Neighborhood Hits	130	Target Neighborhood Hits	64	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

RILP_HUMAN
θ value	0.21417 (rank : 57)	NC score	0.033731 (rank : 92)
Query Neighborhood Hits	130	Target Neighborhood Hits	249	Shared Neighborhood Hits	10
SwissProt Accessions	Q96NA2, Q71RE6, Q9BSL3, Q9BYS3	Gene names	RILP
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

AFF4_HUMAN
θ value	0.365318 (rank : 58)	NC score	0.014751 (rank : 111)
Query Neighborhood Hits	130	Target Neighborhood Hits	611	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

UBP37_HUMAN
θ value	0.47712 (rank : 59)	NC score	0.009425 (rank : 123)
Query Neighborhood Hits	130	Target Neighborhood Hits	208	Shared Neighborhood Hits	10
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

BUB1B_MOUSE
θ value	0.62314 (rank : 60)	NC score	0.016853 (rank : 105)
Query Neighborhood Hits	130	Target Neighborhood Hits	202	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

IWS1_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.021349 (rank : 99)
Query Neighborhood Hits	130	Target Neighborhood Hits	1241	Shared Neighborhood Hits	31
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	0.813845 (rank : 62)	NC score	0.036915 (rank : 91)
Query Neighborhood Hits	130	Target Neighborhood Hits	1258	Shared Neighborhood Hits	40
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KCNG2_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.077872 (rank : 72)
Query Neighborhood Hits	130	Target Neighborhood Hits	83	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

DJBP_MOUSE
θ value	1.06291 (rank : 64)	NC score	0.057582 (rank : 88)
Query Neighborhood Hits	130	Target Neighborhood Hits	152	Shared Neighborhood Hits	14
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

GTSE1_HUMAN
θ value	1.06291 (rank : 65)	NC score	0.019320 (rank : 101)
Query Neighborhood Hits	130	Target Neighborhood Hits	193	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

TPTE2_HUMAN
θ value	1.06291 (rank : 66)	NC score	0.130424 (rank : 52)
Query Neighborhood Hits	130	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

NFM_HUMAN
θ value	1.38821 (rank : 67)	NC score	0.000968 (rank : 150)
Query Neighborhood Hits	130	Target Neighborhood Hits	1328	Shared Neighborhood Hits	34
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

SRRM2_MOUSE
θ value	1.38821 (rank : 68)	NC score	0.018857 (rank : 102)
Query Neighborhood Hits	130	Target Neighborhood Hits	1470	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

APLP2_HUMAN
θ value	1.81305 (rank : 69)	NC score	0.011936 (rank : 118)
Query Neighborhood Hits	130	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

BSCL2_HUMAN
θ value	1.81305 (rank : 70)	NC score	0.024753 (rank : 97)
Query Neighborhood Hits	130	Target Neighborhood Hits	148	Shared Neighborhood Hits	11
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

GPTC8_HUMAN
θ value	1.81305 (rank : 71)	NC score	0.031627 (rank : 93)
Query Neighborhood Hits	130	Target Neighborhood Hits	366	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

PCX3_MOUSE
θ value	1.81305 (rank : 72)	NC score	0.014610 (rank : 112)
Query Neighborhood Hits	130	Target Neighborhood Hits	134	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

SRRM2_HUMAN
θ value	1.81305 (rank : 73)	NC score	0.025280 (rank : 95)
Query Neighborhood Hits	130	Target Neighborhood Hits	1296	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

LDOC1_MOUSE
θ value	2.36792 (rank : 74)	NC score	0.023590 (rank : 98)
Query Neighborhood Hits	130	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TPY9	Gene names	Ldoc1
Domain Architecture	No domain graphic available
Description	Protein LDOC1.

LEO1_MOUSE
θ value	2.36792 (rank : 75)	NC score	0.014129 (rank : 113)
Query Neighborhood Hits	130	Target Neighborhood Hits	946	Shared Neighborhood Hits	32
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MYST3_MOUSE
θ value	2.36792 (rank : 76)	NC score	0.010148 (rank : 121)
Query Neighborhood Hits	130	Target Neighborhood Hits	688	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

ZN318_MOUSE
θ value	2.36792 (rank : 77)	NC score	0.016219 (rank : 107)
Query Neighborhood Hits	130	Target Neighborhood Hits	642	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

AKA12_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.015728 (rank : 109)
Query Neighborhood Hits	130	Target Neighborhood Hits	825	Shared Neighborhood Hits	32
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

DEDD_MOUSE
θ value	3.0926 (rank : 79)	NC score	0.011826 (rank : 119)
Query Neighborhood Hits	130	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1L3, Q7TQH8, Q9R227	Gene names	Dedd
Domain Architecture
Description	Death effector domain-containing protein (DEDPro1).

KI21A_MOUSE
θ value	3.0926 (rank : 80)	NC score	0.001440 (rank : 147)
Query Neighborhood Hits	130	Target Neighborhood Hits	1317	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

TENA_MOUSE
θ value	3.0926 (rank : 81)	NC score	0.000165 (rank : 152)
Query Neighborhood Hits	130	Target Neighborhood Hits	596	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TF3B_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.009222 (rank : 124)
Query Neighborhood Hits	130	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFK2	Gene names	Brf1
Domain Architecture	No domain graphic available
Description	Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) (B- related factor 1) (BRF-1).

VEZA_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.012274 (rank : 117)
Query Neighborhood Hits	130	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HBM0, Q9H2F4, Q9H2U5, Q9NT70, Q9NVW0, Q9UF91	Gene names	VEZT
Domain Architecture	No domain graphic available
Description	Vezatin.

BPAEA_HUMAN
θ value	4.03905 (rank : 84)	NC score	-0.000550 (rank : 154)
Query Neighborhood Hits	130	Target Neighborhood Hits	1369	Shared Neighborhood Hits	19
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DGLA_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.012589 (rank : 115)
Query Neighborhood Hits	130	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4D2, Q6WQJ0	Gene names	NSDDR, C11orf11, KIAA0659
Domain Architecture	No domain graphic available
Description	Sn1-specific diacylglycerol lipase alpha (EC 3.1.1.-) (DGL-alpha) (Neural stem cell-derived dendrite regulator).

DGLA_MOUSE
θ value	4.03905 (rank : 86)	NC score	0.012538 (rank : 116)
Query Neighborhood Hits	130	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q6WQJ1, Q6ZQ76	Gene names	Nsddr, Kiaa0659
Domain Architecture	No domain graphic available
Description	Sn1-specific diacylglycerol lipase alpha (EC 3.1.1.-) (DGL-alpha) (Neural stem cell-derived dendrite regulator).

JIP2_HUMAN
θ value	4.03905 (rank : 87)	NC score	0.009811 (rank : 122)
Query Neighborhood Hits	130	Target Neighborhood Hits	288	Shared Neighborhood Hits	10
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

KCNA6_MOUSE
θ value	4.03905 (rank : 88)	NC score	0.081020 (rank : 68)
Query Neighborhood Hits	130	Target Neighborhood Hits	106	Shared Neighborhood Hits	36
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

SMC3_HUMAN
θ value	4.03905 (rank : 89)	NC score	0.004030 (rank : 134)
Query Neighborhood Hits	130	Target Neighborhood Hits	1186	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	4.03905 (rank : 90)	NC score	0.003903 (rank : 135)
Query Neighborhood Hits	130	Target Neighborhood Hits	1187	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

TP53B_MOUSE
θ value	4.03905 (rank : 91)	NC score	0.021341 (rank : 100)
Query Neighborhood Hits	130	Target Neighborhood Hits	644	Shared Neighborhood Hits	26
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TPR_HUMAN
θ value	4.03905 (rank : 92)	NC score	0.001276 (rank : 148)
Query Neighborhood Hits	130	Target Neighborhood Hits	1921	Shared Neighborhood Hits	33
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TPTE_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.091070 (rank : 63)
Query Neighborhood Hits	130	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

DEDD_HUMAN
θ value	5.27518 (rank : 94)	NC score	0.010210 (rank : 120)
Query Neighborhood Hits	130	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	O75618, O60737	Gene names	DEDD, DEDPRO1, DEFT
Domain Architecture
Description	Death effector domain-containing protein (Death effector domain- containing testicular molecule) (DEDPro1) (FLDED-1).

DHX8_HUMAN
θ value	5.27518 (rank : 95)	NC score	0.002654 (rank : 145)
Query Neighborhood Hits	130	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

DNL3_HUMAN
θ value	5.27518 (rank : 96)	NC score	0.028598 (rank : 94)
Query Neighborhood Hits	130	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

FYCO1_MOUSE
θ value	5.27518 (rank : 97)	NC score	-0.000987 (rank : 155)
Query Neighborhood Hits	130	Target Neighborhood Hits	1059	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

KI21A_HUMAN
θ value	5.27518 (rank : 98)	NC score	-0.001591 (rank : 156)
Query Neighborhood Hits	130	Target Neighborhood Hits	1543	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

MYPN_MOUSE
θ value	5.27518 (rank : 99)	NC score	0.003862 (rank : 136)
Query Neighborhood Hits	130	Target Neighborhood Hits	421	Shared Neighborhood Hits	9
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

TICN3_MOUSE
θ value	5.27518 (rank : 100)	NC score	0.003603 (rank : 141)
Query Neighborhood Hits	130	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

AN32B_MOUSE
θ value	6.88961 (rank : 101)	NC score	0.005410 (rank : 131)
Query Neighborhood Hits	130	Target Neighborhood Hits	236	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

APBA1_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.006852 (rank : 128)
Query Neighborhood Hits	130	Target Neighborhood Hits	325	Shared Neighborhood Hits	12
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

DNL3_MOUSE
θ value	6.88961 (rank : 103)	NC score	0.025280 (rank : 96)
Query Neighborhood Hits	130	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

FOXC2_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.000786 (rank : 151)
Query Neighborhood Hits	130	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

JHD1B_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.002734 (rank : 144)
Query Neighborhood Hits	130	Target Neighborhood Hits	178	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

MLL3_HUMAN
θ value	6.88961 (rank : 106)	NC score	0.003127 (rank : 143)
Query Neighborhood Hits	130	Target Neighborhood Hits	1644	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

OXRP_HUMAN
θ value	6.88961 (rank : 107)	NC score	0.003820 (rank : 137)
Query Neighborhood Hits	130	Target Neighborhood Hits	544	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

RBBP6_HUMAN
θ value	6.88961 (rank : 108)	NC score	0.018316 (rank : 103)
Query Neighborhood Hits	130	Target Neighborhood Hits	1135	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RNF6_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.003675 (rank : 139)
Query Neighborhood Hits	130	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

SCG3_MOUSE
θ value	6.88961 (rank : 110)	NC score	0.005380 (rank : 132)
Query Neighborhood Hits	130	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	P47867	Gene names	Scg3
Domain Architecture	No domain graphic available
Description	Secretogranin-3 precursor (Secretogranin III) (SgIII).

SEN34_MOUSE
θ value	6.88961 (rank : 111)	NC score	0.016198 (rank : 108)
Query Neighborhood Hits	130	Target Neighborhood Hits	158	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

TRI26_MOUSE
θ value	6.88961 (rank : 112)	NC score	-0.000441 (rank : 153)
Query Neighborhood Hits	130	Target Neighborhood Hits	339	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

AP3B2_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.006445 (rank : 129)
Query Neighborhood Hits	130	Target Neighborhood Hits	246	Shared Neighborhood Hits	17
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

BTC_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.008403 (rank : 125)
Query Neighborhood Hits	130	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

CMTA1_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.007311 (rank : 127)
Query Neighborhood Hits	130	Target Neighborhood Hits	217	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

CRKL_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.001229 (rank : 149)
Query Neighborhood Hits	130	Target Neighborhood Hits	307	Shared Neighborhood Hits	3
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

CSTN1_MOUSE
θ value	8.99809 (rank : 117)	NC score	0.003777 (rank : 138)
Query Neighborhood Hits	130	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EPL2	Gene names	Clstn1, Cs1, Cstn1
Domain Architecture
Description	Calsyntenin-1 precursor.

DJBP_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.015191 (rank : 110)
Query Neighborhood Hits	130	Target Neighborhood Hits	156	Shared Neighborhood Hits	6
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

KCNC3_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.112015 (rank : 57)
Query Neighborhood Hits	130	Target Neighborhood Hits	256	Shared Neighborhood Hits	51
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
θ value	8.99809 (rank : 120)	NC score	0.110432 (rank : 58)
Query Neighborhood Hits	130	Target Neighborhood Hits	173	Shared Neighborhood Hits	47
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

MDN1_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.016479 (rank : 106)
Query Neighborhood Hits	130	Target Neighborhood Hits	662	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MYST4_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.005695 (rank : 130)
Query Neighborhood Hits	130	Target Neighborhood Hits	416	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

NASP_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.017760 (rank : 104)
Query Neighborhood Hits	130	Target Neighborhood Hits	709	Shared Neighborhood Hits	30
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NOP14_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.003148 (rank : 142)
Query Neighborhood Hits	130	Target Neighborhood Hits	573	Shared Neighborhood Hits	18
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

OR6Y1_HUMAN
θ value	8.99809 (rank : 125)	NC score	-0.004424 (rank : 157)
Query Neighborhood Hits	130	Target Neighborhood Hits	701	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NGX8, Q6IFS0	Gene names	OR6Y1, OR6Y2
Domain Architecture
Description	Olfactory receptor 6Y1 (Olfactory receptor OR1-11).

PKHG4_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.002333 (rank : 146)
Query Neighborhood Hits	130	Target Neighborhood Hits	200	Shared Neighborhood Hits	3
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

RGS3_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.012840 (rank : 114)
Query Neighborhood Hits	130	Target Neighborhood Hits	1621	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TMC2_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.005310 (rank : 133)
Query Neighborhood Hits	130	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

TXD13_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.007787 (rank : 126)
Query Neighborhood Hits	130	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C0L0, Q3UHC6, Q6ZPW7, Q80X49	Gene names	Txndc13, D2Bwg1356e, Kiaa1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

USP9X_MOUSE
θ value	8.99809 (rank : 130)	NC score	0.003632 (rank : 140)
Query Neighborhood Hits	130	Target Neighborhood Hits	171	Shared Neighborhood Hits	4
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

KCNA1_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.083140 (rank : 65)
Query Neighborhood Hits	130	Target Neighborhood Hits	104	Shared Neighborhood Hits	36
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA1_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.085199 (rank : 64)
Query Neighborhood Hits	130	Target Neighborhood Hits	103	Shared Neighborhood Hits	37
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA2_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.081111 (rank : 67)
Query Neighborhood Hits	130	Target Neighborhood Hits	101	Shared Neighborhood Hits	33
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.082136 (rank : 66)
Query Neighborhood Hits	130	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA3_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.070083 (rank : 76)
Query Neighborhood Hits	130	Target Neighborhood Hits	101	Shared Neighborhood Hits	32
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.069205 (rank : 79)
Query Neighborhood Hits	130	Target Neighborhood Hits	103	Shared Neighborhood Hits	30
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA4_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.060092 (rank : 86)
Query Neighborhood Hits	130	Target Neighborhood Hits	108	Shared Neighborhood Hits	26
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA4_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.060284 (rank : 85)
Query Neighborhood Hits	130	Target Neighborhood Hits	98	Shared Neighborhood Hits	25
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA5_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.067446 (rank : 81)
Query Neighborhood Hits	130	Target Neighborhood Hits	124	Shared Neighborhood Hits	32
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNA5_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.072054 (rank : 74)
Query Neighborhood Hits	130	Target Neighborhood Hits	119	Shared Neighborhood Hits	34
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNA6_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.074342 (rank : 73)
Query Neighborhood Hits	130	Target Neighborhood Hits	100	Shared Neighborhood Hits	33
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNC1_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.129852 (rank : 53)
Query Neighborhood Hits	130	Target Neighborhood Hits	133	Shared Neighborhood Hits	49
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.128118 (rank : 54)
Query Neighborhood Hits	130	Target Neighborhood Hits	133	Shared Neighborhood Hits	49
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC4_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.125048 (rank : 55)
Query Neighborhood Hits	130	Target Neighborhood Hits	141	Shared Neighborhood Hits	48
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC4_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.116626 (rank : 56)
Query Neighborhood Hits	130	Target Neighborhood Hits	130	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNG1_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.078176 (rank : 71)
Query Neighborhood Hits	130	Target Neighborhood Hits	103	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG3_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.107283 (rank : 60)
Query Neighborhood Hits	130	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.105944 (rank : 61)
Query Neighborhood Hits	130	Target Neighborhood Hits	91	Shared Neighborhood Hits	40
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG4_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.069904 (rank : 77)
Query Neighborhood Hits	130	Target Neighborhood Hits	99	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNQ1_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.068017 (rank : 80)
Query Neighborhood Hits	130	Target Neighborhood Hits	99	Shared Neighborhood Hits	30
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ1_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.080680 (rank : 69)
Query Neighborhood Hits	130	Target Neighborhood Hits	175	Shared Neighborhood Hits	34
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ3_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.061215 (rank : 83)
Query Neighborhood Hits	130	Target Neighborhood Hits	114	Shared Neighborhood Hits	32
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.060048 (rank : 87)
Query Neighborhood Hits	130	Target Neighborhood Hits	105	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ5_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.070283 (rank : 75)
Query Neighborhood Hits	130	Target Neighborhood Hits	163	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

MCLN2_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.061098 (rank : 84)
Query Neighborhood Hits	130	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

PKDRE_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.078353 (rank : 70)
Query Neighborhood Hits	130	Target Neighborhood Hits	76	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

TRPV3_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.050902 (rank : 89)
Query Neighborhood Hits	130	Target Neighborhood Hits	198	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

Hits sorted by NC score

CAC1C_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 6)
Query Neighborhood Hits	130	Target Neighborhood Hits	130	Shared Neighborhood Hits	130
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1C_HUMAN
NC score	0.997417 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	130	Target Neighborhood Hits	158	Shared Neighborhood Hits	97
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1S_HUMAN
NC score	0.994515 (rank : 3)	θ value	0 (rank : 12)
Query Neighborhood Hits	130	Target Neighborhood Hits	92	Shared Neighborhood Hits	60
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1D_HUMAN
NC score	0.994293 (rank : 4)	θ value	0 (rank : 7)
Query Neighborhood Hits	130	Target Neighborhood Hits	118	Shared Neighborhood Hits	60
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1S_MOUSE
NC score	0.993423 (rank : 5)	θ value	0 (rank : 13)
Query Neighborhood Hits	130	Target Neighborhood Hits	98	Shared Neighborhood Hits	56
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1F_MOUSE
NC score	0.992222 (rank : 6)	θ value	0 (rank : 11)
Query Neighborhood Hits	130	Target Neighborhood Hits	142	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_HUMAN
NC score	0.991918 (rank : 7)	θ value	0 (rank : 10)
Query Neighborhood Hits	130	Target Neighborhood Hits	141	Shared Neighborhood Hits	61
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1E_MOUSE
NC score	0.958504 (rank : 8)	θ value	0 (rank : 9)
Query Neighborhood Hits	130	Target Neighborhood Hits	167	Shared Neighborhood Hits	59
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
NC score	0.958446 (rank : 9)	θ value	0 (rank : 8)
Query Neighborhood Hits	130	Target Neighborhood Hits	148	Shared Neighborhood Hits	57
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1B_HUMAN
NC score	0.954697 (rank : 10)	θ value	0 (rank : 3)
Query Neighborhood Hits	130	Target Neighborhood Hits	257	Shared Neighborhood Hits	58
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1A_MOUSE
NC score	0.953425 (rank : 11)	θ value	0 (rank : 2)
Query Neighborhood Hits	130	Target Neighborhood Hits	267	Shared Neighborhood Hits	63
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_MOUSE
NC score	0.949188 (rank : 12)	θ value	0 (rank : 4)
Query Neighborhood Hits	130	Target Neighborhood Hits	351	Shared Neighborhood Hits	57
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1A_HUMAN
NC score	0.944698 (rank : 13)	θ value	0 (rank : 1)
Query Neighborhood Hits	130	Target Neighborhood Hits	387	Shared Neighborhood Hits	62
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1I_HUMAN
NC score	0.894870 (rank : 14)	θ value	7.20884e-74 (rank : 15)
Query Neighborhood Hits	130	Target Neighborhood Hits	138	Shared Neighborhood Hits	56
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1H_MOUSE
NC score	0.868803 (rank : 15)	θ value	6.76295e-64 (rank : 26)
Query Neighborhood Hits	130	Target Neighborhood Hits	230	Shared Neighborhood Hits	58
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1H_HUMAN
NC score	0.865666 (rank : 16)	θ value	1.6097e-65 (rank : 21)
Query Neighborhood Hits	130	Target Neighborhood Hits	307	Shared Neighborhood Hits	60
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

SC11A_MOUSE
NC score	0.857583 (rank : 17)	θ value	5.7252e-63 (rank : 28)
Query Neighborhood Hits	130	Target Neighborhood Hits	116	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SC11A_HUMAN
NC score	0.856068 (rank : 18)	θ value	3.02872e-72 (rank : 16)
Query Neighborhood Hits	130	Target Neighborhood Hits	111	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SCN7A_HUMAN
NC score	0.851684 (rank : 19)	θ value	5.67233e-95 (rank : 14)
Query Neighborhood Hits	130	Target Neighborhood Hits	135	Shared Neighborhood Hits	50
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

CAC1G_HUMAN
NC score	0.850315 (rank : 20)	θ value	2.32439e-64 (rank : 24)
Query Neighborhood Hits	130	Target Neighborhood Hits	587	Shared Neighborhood Hits	60
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SCN5A_HUMAN
NC score	0.850197 (rank : 21)	θ value	2.74572e-65 (rank : 22)
Query Neighborhood Hits	130	Target Neighborhood Hits	145	Shared Neighborhood Hits	58
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SCN4A_HUMAN
NC score	0.848654 (rank : 22)	θ value	1.83746e-69 (rank : 19)
Query Neighborhood Hits	130	Target Neighborhood Hits	133	Shared Neighborhood Hits	60
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN3A_HUMAN
NC score	0.842073 (rank : 23)	θ value	6.31527e-70 (rank : 17)
Query Neighborhood Hits	130	Target Neighborhood Hits	115	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SC10A_MOUSE
NC score	0.839518 (rank : 24)	θ value	2.32439e-64 (rank : 25)
Query Neighborhood Hits	130	Target Neighborhood Hits	107	Shared Neighborhood Hits	60
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN2A_HUMAN
NC score	0.839339 (rank : 25)	θ value	8.24801e-70 (rank : 18)
Query Neighborhood Hits	130	Target Neighborhood Hits	157	Shared Neighborhood Hits	60
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN9A_HUMAN
NC score	0.838679 (rank : 26)	θ value	3.4653e-68 (rank : 20)
Query Neighborhood Hits	130	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN8A_HUMAN
NC score	0.837505 (rank : 27)	θ value	8.26713e-62 (rank : 29)
Query Neighborhood Hits	130	Target Neighborhood Hits	135	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN1A_HUMAN
NC score	0.836675 (rank : 28)	θ value	1.36269e-64 (rank : 23)
Query Neighborhood Hits	130	Target Neighborhood Hits	148	Shared Neighborhood Hits	59
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SC10A_HUMAN
NC score	0.835347 (rank : 29)	θ value	1.50663e-63 (rank : 27)
Query Neighborhood Hits	130	Target Neighborhood Hits	116	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SCN8A_MOUSE
NC score	0.834911 (rank : 30)	θ value	1.84173e-61 (rank : 30)
Query Neighborhood Hits	130	Target Neighborhood Hits	136	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

PK2L2_HUMAN
NC score	0.390830 (rank : 31)	θ value	1.38499e-08 (rank : 31)
Query Neighborhood Hits	130	Target Neighborhood Hits	90	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L1_HUMAN
NC score	0.357536 (rank : 32)	θ value	9.92553e-07 (rank : 37)
Query Neighborhood Hits	130	Target Neighborhood Hits	132	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_MOUSE
NC score	0.354284 (rank : 33)	θ value	1.99992e-07 (rank : 32)
Query Neighborhood Hits	130	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_MOUSE
NC score	0.342962 (rank : 34)	θ value	6.43352e-06 (rank : 38)
Query Neighborhood Hits	130	Target Neighborhood Hits	99	Shared Neighborhood Hits	37
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PKD2_HUMAN
NC score	0.337490 (rank : 35)	θ value	4.45536e-07 (rank : 34)
Query Neighborhood Hits	130	Target Neighborhood Hits	105	Shared Neighborhood Hits	35
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCNF1_HUMAN
NC score	0.244528 (rank : 36)	θ value	2.44474e-05 (rank : 39)
Query Neighborhood Hits	130	Target Neighborhood Hits	109	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNV2_HUMAN
NC score	0.231777 (rank : 37)	θ value	9.29e-05 (rank : 40)
Query Neighborhood Hits	130	Target Neighborhood Hits	137	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNB2_HUMAN
NC score	0.216935 (rank : 38)	θ value	4.45536e-07 (rank : 33)
Query Neighborhood Hits	130	Target Neighborhood Hits	212	Shared Neighborhood Hits	59
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS2_MOUSE
NC score	0.205577 (rank : 39)	θ value	0.0330416 (rank : 48)
Query Neighborhood Hits	130	Target Neighborhood Hits	130	Shared Neighborhood Hits	54
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNB1_HUMAN
NC score	0.204607 (rank : 40)	θ value	5.81887e-07 (rank : 35)
Query Neighborhood Hits	130	Target Neighborhood Hits	169	Shared Neighborhood Hits	55
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
NC score	0.204507 (rank : 41)	θ value	5.81887e-07 (rank : 36)
Query Neighborhood Hits	130	Target Neighborhood Hits	154	Shared Neighborhood Hits	54
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNS2_HUMAN
NC score	0.202149 (rank : 42)	θ value	0.0113563 (rank : 44)
Query Neighborhood Hits	130	Target Neighborhood Hits	129	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCND3_MOUSE
NC score	0.180783 (rank : 43)	θ value	0.0330416 (rank : 47)
Query Neighborhood Hits	130	Target Neighborhood Hits	162	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNS3_HUMAN
NC score	0.180676 (rank : 44)	θ value	0.00175202 (rank : 41)
Query Neighborhood Hits	130	Target Neighborhood Hits	125	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCND3_HUMAN
NC score	0.180626 (rank : 45)	θ value	0.0330416 (rank : 46)
Query Neighborhood Hits	130	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND2_MOUSE
NC score	0.174442 (rank : 46)	θ value	0.0563607 (rank : 55)
Query Neighborhood Hits	130	Target Neighborhood Hits	156	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.174288 (rank : 47)	θ value	0.0563607 (rank : 54)
Query Neighborhood Hits	130	Target Neighborhood Hits	154	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND1_MOUSE
NC score	0.165070 (rank : 48)	θ value	0.00665767 (rank : 43)
Query Neighborhood Hits	130	Target Neighborhood Hits	165	Shared Neighborhood Hits	52
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
NC score	0.160719 (rank : 49)	θ value	0.0563607 (rank : 53)
Query Neighborhood Hits	130	Target Neighborhood Hits	160	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNS1_HUMAN
NC score	0.154080 (rank : 50)	θ value	0.0431538 (rank : 52)
Query Neighborhood Hits	130	Target Neighborhood Hits	116	Shared Neighborhood Hits	52
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNS1_MOUSE
NC score	0.143524 (rank : 51)	θ value	0.00509761 (rank : 42)
Query Neighborhood Hits	130	Target Neighborhood Hits	114	Shared Neighborhood Hits	46
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

TPTE2_HUMAN
NC score	0.130424 (rank : 52)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	130	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNC1_HUMAN
NC score	0.129852 (rank : 53)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	130	Target Neighborhood Hits	133	Shared Neighborhood Hits	49
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
NC score	0.128118 (rank : 54)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	130	Target Neighborhood Hits	133	Shared Neighborhood Hits	49
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC4_HUMAN
NC score	0.125048 (rank : 55)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	130	Target Neighborhood Hits	141	Shared Neighborhood Hits	48
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC4_MOUSE
NC score	0.116626 (rank : 56)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	130	Target Neighborhood Hits	130	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNC3_HUMAN
NC score	0.112015 (rank : 57)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	130	Target Neighborhood Hits	256	Shared Neighborhood Hits	51
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
NC score	0.110432 (rank : 58)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	130	Target Neighborhood Hits	173	Shared Neighborhood Hits	47
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

PKDRE_HUMAN
NC score	0.107530 (rank : 59)	θ value	0.163984 (rank : 56)
Query Neighborhood Hits	130	Target Neighborhood Hits	64	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNG3_HUMAN
NC score	0.107283 (rank : 60)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	130	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_MOUSE
NC score	0.105944 (rank : 61)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	130	Target Neighborhood Hits	91	Shared Neighborhood Hits	40
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNQ4_HUMAN
NC score	0.096891 (rank : 62)	θ value	0.0252991 (rank : 45)
Query Neighborhood Hits	130	Target Neighborhood Hits	136	Shared Neighborhood Hits	35
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

TPTE_HUMAN
NC score	0.091070 (rank : 63)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	130	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

KCNA1_MOUSE
NC score	0.085199 (rank : 64)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	130	Target Neighborhood Hits	103	Shared Neighborhood Hits	37
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA1_HUMAN
NC score	0.083140 (rank : 65)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	130	Target Neighborhood Hits	104	Shared Neighborhood Hits	36
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA2_MOUSE
NC score	0.082136 (rank : 66)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	130	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA2_HUMAN
NC score	0.081111 (rank : 67)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	130	Target Neighborhood Hits	101	Shared Neighborhood Hits	33
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA6_MOUSE
NC score	0.081020 (rank : 68)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	130	Target Neighborhood Hits	106	Shared Neighborhood Hits	36
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNQ1_MOUSE
NC score	0.080680 (rank : 69)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	130	Target Neighborhood Hits	175	Shared Neighborhood Hits	34
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

PKDRE_MOUSE
NC score	0.078353 (rank : 70)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	130	Target Neighborhood Hits	76	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNG1_HUMAN
NC score	0.078176 (rank : 71)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	130	Target Neighborhood Hits	103	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG2_HUMAN
NC score	0.077872 (rank : 72)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	130	Target Neighborhood Hits	83	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNA6_HUMAN
NC score	0.074342 (rank : 73)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	130	Target Neighborhood Hits	100	Shared Neighborhood Hits	33
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA5_MOUSE
NC score	0.072054 (rank : 74)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	130	Target Neighborhood Hits	119	Shared Neighborhood Hits	34
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNQ5_HUMAN
NC score	0.070283 (rank : 75)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	130	Target Neighborhood Hits	163	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNA3_HUMAN
NC score	0.070083 (rank : 76)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	130	Target Neighborhood Hits	101	Shared Neighborhood Hits	32
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNG4_HUMAN
NC score	0.069904 (rank : 77)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	130	Target Neighborhood Hits	99	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNQ2_HUMAN
NC score	0.069392 (rank : 78)	θ value	0.0431538 (rank : 50)
Query Neighborhood Hits	130	Target Neighborhood Hits	114	Shared Neighborhood Hits	28
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNA3_MOUSE
NC score	0.069205 (rank : 79)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	130	Target Neighborhood Hits	103	Shared Neighborhood Hits	30
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNQ1_HUMAN
NC score	0.068017 (rank : 80)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	130	Target Neighborhood Hits	99	Shared Neighborhood Hits	30
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNA5_HUMAN
NC score	0.067446 (rank : 81)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	130	Target Neighborhood Hits	124	Shared Neighborhood Hits	32
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNQ2_MOUSE
NC score	0.065404 (rank : 82)	θ value	0.0431538 (rank : 51)
Query Neighborhood Hits	130	Target Neighborhood Hits	163	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ3_HUMAN
NC score	0.061215 (rank : 83)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	130	Target Neighborhood Hits	114	Shared Neighborhood Hits	32
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

MCLN2_MOUSE
NC score	0.061098 (rank : 84)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	130	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

KCNA4_MOUSE
NC score	0.060284 (rank : 85)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	130	Target Neighborhood Hits	98	Shared Neighborhood Hits	25
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA4_HUMAN
NC score	0.060092 (rank : 86)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	130	Target Neighborhood Hits	108	Shared Neighborhood Hits	26
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNQ3_MOUSE
NC score	0.060048 (rank : 87)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	130	Target Neighborhood Hits	105	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

DJBP_MOUSE
NC score	0.057582 (rank : 88)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	130	Target Neighborhood Hits	152	Shared Neighborhood Hits	14
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

TRPV3_HUMAN
NC score	0.050902 (rank : 89)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	130	Target Neighborhood Hits	198	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

NIPBL_HUMAN
NC score	0.037924 (rank : 90)	θ value	0.0330416 (rank : 49)
Query Neighborhood Hits	130	Target Neighborhood Hits	1311	Shared Neighborhood Hits	36
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

IWS1_MOUSE
NC score	0.036915 (rank : 91)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	130	Target Neighborhood Hits	1258	Shared Neighborhood Hits	40
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RILP_HUMAN
NC score	0.033731 (rank : 92)	θ value	0.21417 (rank : 57)
Query Neighborhood Hits	130	Target Neighborhood Hits	249	Shared Neighborhood Hits	10
SwissProt Accessions	Q96NA2, Q71RE6, Q9BSL3, Q9BYS3	Gene names	RILP
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

GPTC8_HUMAN
NC score	0.031627 (rank : 93)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	130	Target Neighborhood Hits	366	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

DNL3_HUMAN
NC score	0.028598 (rank : 94)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	130	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

SRRM2_HUMAN
NC score	0.025280 (rank : 95)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	130	Target Neighborhood Hits	1296	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

DNL3_MOUSE
NC score	0.025280 (rank : 96)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	130	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

BSCL2_HUMAN
NC score	0.024753 (rank : 97)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	130	Target Neighborhood Hits	148	Shared Neighborhood Hits	11
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

LDOC1_MOUSE
NC score	0.023590 (rank : 98)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	130	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TPY9	Gene names	Ldoc1
Domain Architecture	No domain graphic available
Description	Protein LDOC1.

IWS1_HUMAN
NC score	0.021349 (rank : 99)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	130	Target Neighborhood Hits	1241	Shared Neighborhood Hits	31
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TP53B_MOUSE
NC score	0.021341 (rank : 100)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	130	Target Neighborhood Hits	644	Shared Neighborhood Hits	26
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

GTSE1_HUMAN
NC score	0.019320 (rank : 101)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	130	Target Neighborhood Hits	193	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

SRRM2_MOUSE
NC score	0.018857 (rank : 102)	θ value	1.38821 (rank : 68)
Query Neighborhood Hits	130	Target Neighborhood Hits	1470	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

RBBP6_HUMAN
NC score	0.018316 (rank : 103)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	130	Target Neighborhood Hits	1135	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

NASP_HUMAN
NC score	0.017760 (rank : 104)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	130	Target Neighborhood Hits	709	Shared Neighborhood Hits	30
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

BUB1B_MOUSE
NC score	0.016853 (rank : 105)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	130	Target Neighborhood Hits	202	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

MDN1_HUMAN
NC score	0.016479 (rank : 106)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	130	Target Neighborhood Hits	662	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

ZN318_MOUSE
NC score	0.016219 (rank : 107)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	130	Target Neighborhood Hits	642	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

SEN34_MOUSE
NC score	0.016198 (rank : 108)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	130	Target Neighborhood Hits	158	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

AKA12_HUMAN
NC score	0.015728 (rank : 109)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	130	Target Neighborhood Hits	825	Shared Neighborhood Hits	32
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

DJBP_HUMAN
NC score	0.015191 (rank : 110)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	130	Target Neighborhood Hits	156	Shared Neighborhood Hits	6
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

AFF4_HUMAN
NC score	0.014751 (rank : 111)	θ value	0.365318 (rank : 58)
Query Neighborhood Hits	130	Target Neighborhood Hits	611	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

PCX3_MOUSE
NC score	0.014610 (rank : 112)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	130	Target Neighborhood Hits	134	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

LEO1_MOUSE
NC score	0.014129 (rank : 113)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	130	Target Neighborhood Hits	946	Shared Neighborhood Hits	32
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

RGS3_MOUSE
NC score	0.012840 (rank : 114)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	130	Target Neighborhood Hits	1621	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

DGLA_HUMAN
NC score	0.012589 (rank : 115)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	130	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4D2, Q6WQJ0	Gene names	NSDDR, C11orf11, KIAA0659
Domain Architecture	No domain graphic available
Description	Sn1-specific diacylglycerol lipase alpha (EC 3.1.1.-) (DGL-alpha) (Neural stem cell-derived dendrite regulator).

DGLA_MOUSE
NC score	0.012538 (rank : 116)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	130	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q6WQJ1, Q6ZQ76	Gene names	Nsddr, Kiaa0659
Domain Architecture	No domain graphic available
Description	Sn1-specific diacylglycerol lipase alpha (EC 3.1.1.-) (DGL-alpha) (Neural stem cell-derived dendrite regulator).

VEZA_HUMAN
NC score	0.012274 (rank : 117)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	130	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HBM0, Q9H2F4, Q9H2U5, Q9NT70, Q9NVW0, Q9UF91	Gene names	VEZT
Domain Architecture	No domain graphic available
Description	Vezatin.

APLP2_HUMAN
NC score	0.011936 (rank : 118)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	130	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

DEDD_MOUSE
NC score	0.011826 (rank : 119)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	130	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1L3, Q7TQH8, Q9R227	Gene names	Dedd
Domain Architecture
Description	Death effector domain-containing protein (DEDPro1).

DEDD_HUMAN
NC score	0.010210 (rank : 120)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	130	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	O75618, O60737	Gene names	DEDD, DEDPRO1, DEFT
Domain Architecture
Description	Death effector domain-containing protein (Death effector domain- containing testicular molecule) (DEDPro1) (FLDED-1).

MYST3_MOUSE
NC score	0.010148 (rank : 121)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	130	Target Neighborhood Hits	688	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

JIP2_HUMAN
NC score	0.009811 (rank : 122)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	130	Target Neighborhood Hits	288	Shared Neighborhood Hits	10
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

UBP37_HUMAN
NC score	0.009425 (rank : 123)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	130	Target Neighborhood Hits	208	Shared Neighborhood Hits	10
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

TF3B_MOUSE
NC score	0.009222 (rank : 124)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	130	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFK2	Gene names	Brf1
Domain Architecture	No domain graphic available
Description	Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) (B- related factor 1) (BRF-1).

BTC_HUMAN
NC score	0.008403 (rank : 125)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	130	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

TXD13_MOUSE
NC score	0.007787 (rank : 126)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	130	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C0L0, Q3UHC6, Q6ZPW7, Q80X49	Gene names	Txndc13, D2Bwg1356e, Kiaa1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

CMTA1_HUMAN
NC score	0.007311 (rank : 127)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	130	Target Neighborhood Hits	217	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

APBA1_HUMAN
NC score	0.006852 (rank : 128)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	130	Target Neighborhood Hits	325	Shared Neighborhood Hits	12
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

AP3B2_HUMAN
NC score	0.006445 (rank : 129)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	130	Target Neighborhood Hits	246	Shared Neighborhood Hits	17
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

MYST4_MOUSE
NC score	0.005695 (rank : 130)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	130	Target Neighborhood Hits	416	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

AN32B_MOUSE
NC score	0.005410 (rank : 131)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	130	Target Neighborhood Hits	236	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

SCG3_MOUSE
NC score	0.005380 (rank : 132)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	130	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	P47867	Gene names	Scg3
Domain Architecture	No domain graphic available
Description	Secretogranin-3 precursor (Secretogranin III) (SgIII).

TMC2_HUMAN
NC score	0.005310 (rank : 133)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	130	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

SMC3_HUMAN
NC score	0.004030 (rank : 134)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	130	Target Neighborhood Hits	1186	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
NC score	0.003903 (rank : 135)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	130	Target Neighborhood Hits	1187	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

MYPN_MOUSE
NC score	0.003862 (rank : 136)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	130	Target Neighborhood Hits	421	Shared Neighborhood Hits	9
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

OXRP_HUMAN
NC score	0.003820 (rank : 137)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	130	Target Neighborhood Hits	544	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

CSTN1_MOUSE
NC score	0.003777 (rank : 138)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	130	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EPL2	Gene names	Clstn1, Cs1, Cstn1
Domain Architecture
Description	Calsyntenin-1 precursor.

RNF6_HUMAN
NC score	0.003675 (rank : 139)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	130	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

USP9X_MOUSE
NC score	0.003632 (rank : 140)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	130	Target Neighborhood Hits	171	Shared Neighborhood Hits	4
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

TICN3_MOUSE
NC score	0.003603 (rank : 141)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	130	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

NOP14_HUMAN
NC score	0.003148 (rank : 142)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	130	Target Neighborhood Hits	573	Shared Neighborhood Hits	18
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

MLL3_HUMAN
NC score	0.003127 (rank : 143)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	130	Target Neighborhood Hits	1644	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

JHD1B_HUMAN
NC score	0.002734 (rank : 144)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	130	Target Neighborhood Hits	178	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

DHX8_HUMAN
NC score	0.002654 (rank : 145)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	130	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

PKHG4_HUMAN
NC score	0.002333 (rank : 146)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	130	Target Neighborhood Hits	200	Shared Neighborhood Hits	3
SwissProt Accessions	Q58EX7, Q4G0J8, Q4H485, Q56A69, Q9H7K4, Q9UFW0	Gene names	PLEKHG4, PRTPHN1
Domain Architecture	No domain graphic available
Description	Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1).

KI21A_MOUSE
NC score	0.001440 (rank : 147)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	130	Target Neighborhood Hits	1317	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

TPR_HUMAN
NC score	0.001276 (rank : 148)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	130	Target Neighborhood Hits	1921	Shared Neighborhood Hits	33
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CRKL_MOUSE
NC score	0.001229 (rank : 149)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	130	Target Neighborhood Hits	307	Shared Neighborhood Hits	3
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

NFM_HUMAN
NC score	0.000968 (rank : 150)	θ value	1.38821 (rank : 67)
Query Neighborhood Hits	130	Target Neighborhood Hits	1328	Shared Neighborhood Hits	34
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

FOXC2_HUMAN
NC score	0.000786 (rank : 151)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	130	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

TENA_MOUSE
NC score	0.000165 (rank : 152)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	130	Target Neighborhood Hits	596	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TRI26_MOUSE
NC score	-0.000441 (rank : 153)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	130	Target Neighborhood Hits	339	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

BPAEA_HUMAN
NC score	-0.000550 (rank : 154)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	130	Target Neighborhood Hits	1369	Shared Neighborhood Hits	19
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

FYCO1_MOUSE
NC score	-0.000987 (rank : 155)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	130	Target Neighborhood Hits	1059	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

KI21A_HUMAN
NC score	-0.001591 (rank : 156)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	130	Target Neighborhood Hits	1543	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

OR6Y1_HUMAN
NC score	-0.004424 (rank : 157)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	130	Target Neighborhood Hits	701	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NGX8, Q6IFS0	Gene names	OR6Y1, OR6Y2
Domain Architecture
Description	Olfactory receptor 6Y1 (Olfactory receptor OR1-11).