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Network neighborhood for query Sequence : MCLN2_MOUSE

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MCLN2_MOUSE
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MCLN2_HUMAN
θ value	0 (rank : 1)	NC score	0.995978 (rank : 2)
Query Neighborhood Hits	31	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZK6, Q8N9R3	Gene names	MCOLN2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

MCLN2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

MCLN3_MOUSE
θ value	2.32313e-181 (rank : 3)	NC score	0.986200 (rank : 4)
Query Neighborhood Hits	31	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4F0, Q8BS73, Q8BSG1, Q8CDB2	Gene names	Mcoln3
Domain Architecture	No domain graphic available
Description	Mucolipin-3.

MCLN3_HUMAN
θ value	8.00302e-174 (rank : 4)	NC score	0.986926 (rank : 3)
Query Neighborhood Hits	31	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TDD5, Q5T4H5, Q5T4H6, Q9NV09	Gene names	MCOLN3
Domain Architecture	No domain graphic available
Description	Mucolipin-3.

MCLN1_MOUSE
θ value	5.59392e-143 (rank : 5)	NC score	0.976169 (rank : 6)
Query Neighborhood Hits	31	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	Q99J21	Gene names	Mcoln1
Domain Architecture	No domain graphic available
Description	Mucolipin-1 (Mucolipidin).

MCLN1_HUMAN
θ value	1.42583e-138 (rank : 6)	NC score	0.976452 (rank : 5)
Query Neighborhood Hits	31	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q9GZU1, Q7Z4F7, Q9H292, Q9H4B3, Q9H4B5	Gene names	MCOLN1, ML4
Domain Architecture	No domain graphic available
Description	Mucolipin-1 (Mucolipidin) (MG-2).

PK2L2_MOUSE
θ value	1.9326e-10 (rank : 7)	NC score	0.427578 (rank : 7)
Query Neighborhood Hits	31	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L2_HUMAN
θ value	1.25267e-09 (rank : 8)	NC score	0.408413 (rank : 8)
Query Neighborhood Hits	31	Target Neighborhood Hits	90	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_HUMAN
θ value	4.0297e-08 (rank : 9)	NC score	0.379497 (rank : 10)
Query Neighborhood Hits	31	Target Neighborhood Hits	105	Shared Neighborhood Hits	24
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

PKD2_MOUSE
θ value	5.26297e-08 (rank : 10)	NC score	0.394681 (rank : 9)
Query Neighborhood Hits	31	Target Neighborhood Hits	99	Shared Neighborhood Hits	25
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PK2L1_HUMAN
θ value	9.92553e-07 (rank : 11)	NC score	0.360002 (rank : 11)
Query Neighborhood Hits	31	Target Neighborhood Hits	132	Shared Neighborhood Hits	25
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PKDRE_HUMAN
θ value	0.000461057 (rank : 12)	NC score	0.309969 (rank : 12)
Query Neighborhood Hits	31	Target Neighborhood Hits	64	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

CAC1E_HUMAN
θ value	0.0148317 (rank : 13)	NC score	0.083502 (rank : 17)
Query Neighborhood Hits	31	Target Neighborhood Hits	148	Shared Neighborhood Hits	19
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	0.0193708 (rank : 14)	NC score	0.083221 (rank : 18)
Query Neighborhood Hits	31	Target Neighborhood Hits	167	Shared Neighborhood Hits	19
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

PKDRE_MOUSE
θ value	0.0252991 (rank : 15)	NC score	0.272470 (rank : 13)
Query Neighborhood Hits	31	Target Neighborhood Hits	76	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

CAC1B_HUMAN
θ value	0.0736092 (rank : 16)	NC score	0.097388 (rank : 14)
Query Neighborhood Hits	31	Target Neighborhood Hits	257	Shared Neighborhood Hits	22
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

TRPV5_MOUSE
θ value	0.0736092 (rank : 17)	NC score	0.064530 (rank : 21)
Query Neighborhood Hits	31	Target Neighborhood Hits	278	Shared Neighborhood Hits	10
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

CAC1B_MOUSE
θ value	0.163984 (rank : 18)	NC score	0.094414 (rank : 15)
Query Neighborhood Hits	31	Target Neighborhood Hits	351	Shared Neighborhood Hits	22
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

RN123_HUMAN
θ value	0.62314 (rank : 19)	NC score	0.033125 (rank : 36)
Query Neighborhood Hits	31	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

CAC1A_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.077166 (rank : 20)
Query Neighborhood Hits	31	Target Neighborhood Hits	387	Shared Neighborhood Hits	20
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.078046 (rank : 19)
Query Neighborhood Hits	31	Target Neighborhood Hits	267	Shared Neighborhood Hits	20
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1G_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.060051 (rank : 28)
Query Neighborhood Hits	31	Target Neighborhood Hits	587	Shared Neighborhood Hits	20
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

OR1D4_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.000520 (rank : 40)
Query Neighborhood Hits	31	Target Neighborhood Hits	781	Shared Neighborhood Hits	3
SwissProt Accessions	P47884, Q96RA5, Q9UM75	Gene names	OR1D4
Domain Architecture
Description	Olfactory receptor 1D4 (Olfactory receptor 17-30) (OR17-30).

CAC1H_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.055333 (rank : 33)
Query Neighborhood Hits	31	Target Neighborhood Hits	307	Shared Neighborhood Hits	17
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CAC1H_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.054612 (rank : 34)
Query Neighborhood Hits	31	Target Neighborhood Hits	230	Shared Neighborhood Hits	17
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1I_HUMAN
θ value	2.36792 (rank : 26)	NC score	0.062362 (rank : 23)
Query Neighborhood Hits	31	Target Neighborhood Hits	138	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

RN123_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.029446 (rank : 37)
Query Neighborhood Hits	31	Target Neighborhood Hits	174	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

OR1D5_HUMAN
θ value	5.27518 (rank : 28)	NC score	-0.000082 (rank : 41)
Query Neighborhood Hits	31	Target Neighborhood Hits	758	Shared Neighborhood Hits	3
SwissProt Accessions	P58170, Q96RA6	Gene names	OR1D5
Domain Architecture
Description	Olfactory receptor 1D5 (Olfactory receptor 17-31) (OR17-31).

CNGB3_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.020543 (rank : 38)
Query Neighborhood Hits	31	Target Neighborhood Hits	206	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CHSS2_HUMAN
θ value	8.99809 (rank : 30)	NC score	0.006915 (rank : 39)
Query Neighborhood Hits	31	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZ52, Q6UXD6, Q7L4G1, Q9H0F8, Q9H618	Gene names	CSS2, CHPF
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl- proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase) (Chondroitin-polymerizing factor).

SC11A_MOUSE
θ value	8.99809 (rank : 31)	NC score	0.051605 (rank : 35)
Query Neighborhood Hits	31	Target Neighborhood Hits	116	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

CAC1C_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.060453 (rank : 27)
Query Neighborhood Hits	31	Target Neighborhood Hits	158	Shared Neighborhood Hits	17
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1C_MOUSE
θ value	θ > 10 (rank : 33)	NC score	0.061098 (rank : 25)
Query Neighborhood Hits	31	Target Neighborhood Hits	130	Shared Neighborhood Hits	17
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1D_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.060758 (rank : 26)
Query Neighborhood Hits	31	Target Neighborhood Hits	118	Shared Neighborhood Hits	17
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1F_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.061309 (rank : 24)
Query Neighborhood Hits	31	Target Neighborhood Hits	141	Shared Neighborhood Hits	16
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.064396 (rank : 22)
Query Neighborhood Hits	31	Target Neighborhood Hits	142	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1S_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.056948 (rank : 29)
Query Neighborhood Hits	31	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1S_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.056680 (rank : 30)
Query Neighborhood Hits	31	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

PK1L1_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.092766 (rank : 16)
Query Neighborhood Hits	31	Target Neighborhood Hits	140	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

PKD1_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.055414 (rank : 32)
Query Neighborhood Hits	31	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

SC11A_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.055727 (rank : 31)
Query Neighborhood Hits	31	Target Neighborhood Hits	111	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

Hits sorted by NC score

MCLN2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	31	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

MCLN2_HUMAN
NC score	0.995978 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	31	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZK6, Q8N9R3	Gene names	MCOLN2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

MCLN3_HUMAN
NC score	0.986926 (rank : 3)	θ value	8.00302e-174 (rank : 4)
Query Neighborhood Hits	31	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TDD5, Q5T4H5, Q5T4H6, Q9NV09	Gene names	MCOLN3
Domain Architecture	No domain graphic available
Description	Mucolipin-3.

MCLN3_MOUSE
NC score	0.986200 (rank : 4)	θ value	2.32313e-181 (rank : 3)
Query Neighborhood Hits	31	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4F0, Q8BS73, Q8BSG1, Q8CDB2	Gene names	Mcoln3
Domain Architecture	No domain graphic available
Description	Mucolipin-3.

MCLN1_HUMAN
NC score	0.976452 (rank : 5)	θ value	1.42583e-138 (rank : 6)
Query Neighborhood Hits	31	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	Q9GZU1, Q7Z4F7, Q9H292, Q9H4B3, Q9H4B5	Gene names	MCOLN1, ML4
Domain Architecture	No domain graphic available
Description	Mucolipin-1 (Mucolipidin) (MG-2).

MCLN1_MOUSE
NC score	0.976169 (rank : 6)	θ value	5.59392e-143 (rank : 5)
Query Neighborhood Hits	31	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	Q99J21	Gene names	Mcoln1
Domain Architecture	No domain graphic available
Description	Mucolipin-1 (Mucolipidin).

PK2L2_MOUSE
NC score	0.427578 (rank : 7)	θ value	1.9326e-10 (rank : 7)
Query Neighborhood Hits	31	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L2_HUMAN
NC score	0.408413 (rank : 8)	θ value	1.25267e-09 (rank : 8)
Query Neighborhood Hits	31	Target Neighborhood Hits	90	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_MOUSE
NC score	0.394681 (rank : 9)	θ value	5.26297e-08 (rank : 10)
Query Neighborhood Hits	31	Target Neighborhood Hits	99	Shared Neighborhood Hits	25
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PKD2_HUMAN
NC score	0.379497 (rank : 10)	θ value	4.0297e-08 (rank : 9)
Query Neighborhood Hits	31	Target Neighborhood Hits	105	Shared Neighborhood Hits	24
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

PK2L1_HUMAN
NC score	0.360002 (rank : 11)	θ value	9.92553e-07 (rank : 11)
Query Neighborhood Hits	31	Target Neighborhood Hits	132	Shared Neighborhood Hits	25
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PKDRE_HUMAN
NC score	0.309969 (rank : 12)	θ value	0.000461057 (rank : 12)
Query Neighborhood Hits	31	Target Neighborhood Hits	64	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PKDRE_MOUSE
NC score	0.272470 (rank : 13)	θ value	0.0252991 (rank : 15)
Query Neighborhood Hits	31	Target Neighborhood Hits	76	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

CAC1B_HUMAN
NC score	0.097388 (rank : 14)	θ value	0.0736092 (rank : 16)
Query Neighborhood Hits	31	Target Neighborhood Hits	257	Shared Neighborhood Hits	22
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1B_MOUSE
NC score	0.094414 (rank : 15)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	31	Target Neighborhood Hits	351	Shared Neighborhood Hits	22
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

PK1L1_HUMAN
NC score	0.092766 (rank : 16)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	31	Target Neighborhood Hits	140	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

CAC1E_HUMAN
NC score	0.083502 (rank : 17)	θ value	0.0148317 (rank : 13)
Query Neighborhood Hits	31	Target Neighborhood Hits	148	Shared Neighborhood Hits	19
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
NC score	0.083221 (rank : 18)	θ value	0.0193708 (rank : 14)
Query Neighborhood Hits	31	Target Neighborhood Hits	167	Shared Neighborhood Hits	19
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1A_MOUSE
NC score	0.078046 (rank : 19)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	31	Target Neighborhood Hits	267	Shared Neighborhood Hits	20
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_HUMAN
NC score	0.077166 (rank : 20)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	31	Target Neighborhood Hits	387	Shared Neighborhood Hits	20
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

TRPV5_MOUSE
NC score	0.064530 (rank : 21)	θ value	0.0736092 (rank : 17)
Query Neighborhood Hits	31	Target Neighborhood Hits	278	Shared Neighborhood Hits	10
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

CAC1F_MOUSE
NC score	0.064396 (rank : 22)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	31	Target Neighborhood Hits	142	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1I_HUMAN
NC score	0.062362 (rank : 23)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	31	Target Neighborhood Hits	138	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1F_HUMAN
NC score	0.061309 (rank : 24)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	31	Target Neighborhood Hits	141	Shared Neighborhood Hits	16
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1C_MOUSE
NC score	0.061098 (rank : 25)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	31	Target Neighborhood Hits	130	Shared Neighborhood Hits	17
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1D_HUMAN
NC score	0.060758 (rank : 26)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	31	Target Neighborhood Hits	118	Shared Neighborhood Hits	17
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1C_HUMAN
NC score	0.060453 (rank : 27)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	31	Target Neighborhood Hits	158	Shared Neighborhood Hits	17
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1G_HUMAN
NC score	0.060051 (rank : 28)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	31	Target Neighborhood Hits	587	Shared Neighborhood Hits	20
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1S_HUMAN
NC score	0.056948 (rank : 29)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	31	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1S_MOUSE
NC score	0.056680 (rank : 30)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	31	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SC11A_HUMAN
NC score	0.055727 (rank : 31)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	31	Target Neighborhood Hits	111	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

PKD1_HUMAN
NC score	0.055414 (rank : 32)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	31	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

CAC1H_HUMAN
NC score	0.055333 (rank : 33)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	31	Target Neighborhood Hits	307	Shared Neighborhood Hits	17
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CAC1H_MOUSE
NC score	0.054612 (rank : 34)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	31	Target Neighborhood Hits	230	Shared Neighborhood Hits	17
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

SC11A_MOUSE
NC score	0.051605 (rank : 35)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	31	Target Neighborhood Hits	116	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

RN123_HUMAN
NC score	0.033125 (rank : 36)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	31	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
NC score	0.029446 (rank : 37)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	31	Target Neighborhood Hits	174	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

CNGB3_HUMAN
NC score	0.020543 (rank : 38)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	31	Target Neighborhood Hits	206	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CHSS2_HUMAN
NC score	0.006915 (rank : 39)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	31	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZ52, Q6UXD6, Q7L4G1, Q9H0F8, Q9H618	Gene names	CSS2, CHPF
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl- proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase) (Chondroitin-polymerizing factor).

OR1D4_HUMAN
NC score	0.000520 (rank : 40)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	31	Target Neighborhood Hits	781	Shared Neighborhood Hits	3
SwissProt Accessions	P47884, Q96RA5, Q9UM75	Gene names	OR1D4
Domain Architecture
Description	Olfactory receptor 1D4 (Olfactory receptor 17-30) (OR17-30).

OR1D5_HUMAN
NC score	-0.000082 (rank : 41)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	31	Target Neighborhood Hits	758	Shared Neighborhood Hits	3
SwissProt Accessions	P58170, Q96RA6	Gene names	OR1D5
Domain Architecture
Description	Olfactory receptor 1D5 (Olfactory receptor 17-31) (OR17-31).