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Network neighborhood for query Sequence : CHSS2_HUMAN

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CHSS2_HUMAN
SwissProt Accessions	Q8IZ52, Q6UXD6, Q7L4G1, Q9H0F8, Q9H618	Gene names	CSS2, CHPF
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl- proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase) (Chondroitin-polymerizing factor).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CHGUT_HUMAN
θ value	0 (rank : 1)	NC score	0.978275 (rank : 3)
Query Neighborhood Hits	29	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P2E5, Q6P2I4, Q6UXD2	Gene names	CSGLCAT, KIAA1402
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate glucuronyltransferase (EC 2.4.1.226) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (Chondroitin glucuronyltransferase II) (CSGlcA-T).

CHSS2_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	29	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IZ52, Q6UXD6, Q7L4G1, Q9H0F8, Q9H618	Gene names	CSS2, CHPF
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl- proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase) (Chondroitin-polymerizing factor).

CHSS2_MOUSE
θ value	0 (rank : 3)	NC score	0.998362 (rank : 2)
Query Neighborhood Hits	29	Target Neighborhood Hits	29	Shared Neighborhood Hits	18
SwissProt Accessions	Q6IQX7	Gene names	Css2, D1Bwg1363e
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl- proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase).

CHSS1_MOUSE
θ value	3.4976e-36 (rank : 4)	NC score	0.711708 (rank : 6)
Query Neighborhood Hits	29	Target Neighborhood Hits	56	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZQ11	Gene names	Chsy1, Kiaa0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase) (Chondroitin sulfate synthase 1) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

CHSS1_HUMAN
θ value	4.568e-36 (rank : 5)	NC score	0.713684 (rank : 5)
Query Neighborhood Hits	29	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q86X52, Q6UX38, Q7LFU5, Q9Y2J5	Gene names	CHSY1, CHSY, CSS1, KIAA0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase 1) (Chondroitin sulfate synthase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

CHSS3_HUMAN
θ value	3.27365e-34 (rank : 6)	NC score	0.719303 (rank : 4)
Query Neighborhood Hits	29	Target Neighborhood Hits	97	Shared Neighborhood Hits	12
SwissProt Accessions	Q70JA7, Q76L22, Q86Y52	Gene names	CSS3, CHSY2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 3 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (Chondroitin synthase 2) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II) (Carbohydrate synthase 2).

CGAT2_HUMAN
θ value	1.02475e-11 (rank : 7)	NC score	0.526527 (rank : 7)
Query Neighborhood Hits	29	Target Neighborhood Hits	59	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N6G5, Q6MZJ5, Q6MZP6, Q8TCH4, Q9P1I6	Gene names	GALNACT2, CHGN2
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (GalNAcT-2) (beta4GalNAcT-2).

CGAT2_MOUSE
θ value	2.98157e-11 (rank : 8)	NC score	0.525779 (rank : 8)
Query Neighborhood Hits	29	Target Neighborhood Hits	61	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C1F4, Q6PAP6, Q8R5A2, Q9D2M1	Gene names	Galnact2, Chgn2
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (GalNAcT-2) (beta4GalNAcT-2).

CGAT1_MOUSE
θ value	3.29651e-10 (rank : 9)	NC score	0.513060 (rank : 9)
Query Neighborhood Hits	29	Target Neighborhood Hits	61	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BJQ9, Q3UZX6, Q8BWV9, Q8BZU7, Q8C195, Q8R0M6	Gene names	Galnact1, Chgn
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.174) (beta4GalNAcT-1).

CGAT1_HUMAN
θ value	1.25267e-09 (rank : 10)	NC score	0.509589 (rank : 10)
Query Neighborhood Hits	29	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TDX6, Q6P9G6, Q8IUF9, Q9NSQ7, Q9NUM9	Gene names	GALNACT1, CHGN
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.174) (beta4GalNAcT-1).

B4GN4_HUMAN
θ value	0.0431538 (rank : 11)	NC score	0.230277 (rank : 11)
Query Neighborhood Hits	29	Target Neighborhood Hits	131	Shared Neighborhood Hits	18
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

B4GN4_MOUSE
θ value	0.0563607 (rank : 12)	NC score	0.229030 (rank : 12)
Query Neighborhood Hits	29	Target Neighborhood Hits	129	Shared Neighborhood Hits	12
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

ZFHX2_HUMAN
θ value	0.47712 (rank : 13)	NC score	0.024152 (rank : 23)
Query Neighborhood Hits	29	Target Neighborhood Hits	1178	Shared Neighborhood Hits	10
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

NKX22_HUMAN
θ value	2.36792 (rank : 14)	NC score	0.013558 (rank : 32)
Query Neighborhood Hits	29	Target Neighborhood Hits	342	Shared Neighborhood Hits	4
SwissProt Accessions	O95096	Gene names	NKX2-2, NKX2.2, NKX2B
Domain Architecture
Description	Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B).

TRI66_MOUSE
θ value	2.36792 (rank : 15)	NC score	0.015340 (rank : 31)
Query Neighborhood Hits	29	Target Neighborhood Hits	491	Shared Neighborhood Hits	9
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

GAK12_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.023708 (rank : 24)
Query Neighborhood Hits	29	Target Neighborhood Hits	374	Shared Neighborhood Hits	12
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CV019_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.024913 (rank : 22)
Query Neighborhood Hits	29	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q13769, O60839, Q9UPZ5	Gene names	C22orf19, KIAA0983
Domain Architecture	No domain graphic available
Description	Protein C22orf19 (NF2/meningioma region protein pK1.3) (Placental protein 39.2).

KITM_MOUSE
θ value	4.03905 (rank : 18)	NC score	0.027515 (rank : 21)
Query Neighborhood Hits	29	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R088	Gene names	Tk2
Domain Architecture
Description	Thymidine kinase 2, mitochondrial precursor (EC 2.7.1.21) (Mt-TK).

G3ST3_MOUSE
θ value	5.27518 (rank : 19)	NC score	0.021262 (rank : 25)
Query Neighborhood Hits	29	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P61315	Gene names	Gal3st3
Domain Architecture	No domain graphic available
Description	Galactose-3-O-sulfotransferase 3 (EC 2.8.2.-) (Galbeta1-3GalNAc 3'- sulfotransferase) (Beta-galactose-3-O-sulfotransferase 3).

XKR7_HUMAN
θ value	5.27518 (rank : 20)	NC score	0.010337 (rank : 33)
Query Neighborhood Hits	29	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q5GH72, Q9NUG5	Gene names	XKR7, C20orf159, XRG7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

GAK11_HUMAN
θ value	6.88961 (rank : 21)	NC score	0.019587 (rank : 27)
Query Neighborhood Hits	29	Target Neighborhood Hits	409	Shared Neighborhood Hits	11
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	6.88961 (rank : 22)	NC score	0.019528 (rank : 28)
Query Neighborhood Hits	29	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	6.88961 (rank : 23)	NC score	0.019601 (rank : 26)
Query Neighborhood Hits	29	Target Neighborhood Hits	415	Shared Neighborhood Hits	11
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK5_HUMAN
θ value	6.88961 (rank : 24)	NC score	0.019438 (rank : 29)
Query Neighborhood Hits	29	Target Neighborhood Hits	429	Shared Neighborhood Hits	10
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
θ value	6.88961 (rank : 25)	NC score	0.019346 (rank : 30)
Query Neighborhood Hits	29	Target Neighborhood Hits	392	Shared Neighborhood Hits	10
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PRRT3_HUMAN
θ value	6.88961 (rank : 26)	NC score	0.005702 (rank : 37)
Query Neighborhood Hits	29	Target Neighborhood Hits	998	Shared Neighborhood Hits	7
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

TSH1_HUMAN
θ value	6.88961 (rank : 27)	NC score	0.009850 (rank : 34)
Query Neighborhood Hits	29	Target Neighborhood Hits	558	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

TSH1_MOUSE
θ value	6.88961 (rank : 28)	NC score	0.009535 (rank : 35)
Query Neighborhood Hits	29	Target Neighborhood Hits	675	Shared Neighborhood Hits	3
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

MCLN2_MOUSE
θ value	8.99809 (rank : 29)	NC score	0.006915 (rank : 36)
Query Neighborhood Hits	29	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

B3GLT_HUMAN
θ value	θ > 10 (rank : 30)	NC score	0.117870 (rank : 16)
Query Neighborhood Hits	29	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q6Y288, Q5W0H2, Q6NUI3	Gene names	B3GALTL, B3GTL
Domain Architecture	No domain graphic available
Description	Beta-1,3-glucosyltransferase (EC 2.4.1.-) (Beta3Glc-T) (Beta-3- glycosyltransferase-like).

B3GLT_MOUSE
θ value	θ > 10 (rank : 31)	NC score	0.125856 (rank : 15)
Query Neighborhood Hits	29	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHT6, Q0PCR7, Q149S5	Gene names	B3galtl, Gm1057
Domain Architecture	No domain graphic available
Description	Beta-1,3-glucosyltransferase (EC 2.4.1.-) (Beta3Glc-T) (Beta-3- glycosyltransferase-like).

B4GN3_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.180529 (rank : 13)
Query Neighborhood Hits	29	Target Neighborhood Hits	128	Shared Neighborhood Hits	11
SwissProt Accessions	Q6L9W6, Q6ZNC1, Q8N7T6	Gene names	B4GALNT3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

B4GN3_MOUSE
θ value	θ > 10 (rank : 33)	NC score	0.177322 (rank : 14)
Query Neighborhood Hits	29	Target Neighborhood Hits	49	Shared Neighborhood Hits	9
SwissProt Accessions	Q6L8S8	Gene names	B4galnt3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

LFNG_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.059820 (rank : 20)
Query Neighborhood Hits	29	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NES3, O00589, Q96C39, Q9UJW5	Gene names	LFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

LFNG_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.069934 (rank : 18)
Query Neighborhood Hits	29	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	O09010, Q3U659, Q8K3F1, Q9DC10	Gene names	Lfng
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

RFNG_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.067528 (rank : 19)
Query Neighborhood Hits	29	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y644, O00588	Gene names	RFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase radical fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

RFNG_MOUSE
θ value	θ > 10 (rank : 37)	NC score	0.091069 (rank : 17)
Query Neighborhood Hits	29	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	O09009	Gene names	Rfng
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase radical fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

Hits sorted by NC score

CHSS2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	29	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IZ52, Q6UXD6, Q7L4G1, Q9H0F8, Q9H618	Gene names	CSS2, CHPF
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl- proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase) (Chondroitin-polymerizing factor).

CHSS2_MOUSE
NC score	0.998362 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	29	Target Neighborhood Hits	29	Shared Neighborhood Hits	18
SwissProt Accessions	Q6IQX7	Gene names	Css2, D1Bwg1363e
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl- proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase).

CHGUT_HUMAN
NC score	0.978275 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	29	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P2E5, Q6P2I4, Q6UXD2	Gene names	CSGLCAT, KIAA1402
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate glucuronyltransferase (EC 2.4.1.226) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (Chondroitin glucuronyltransferase II) (CSGlcA-T).

CHSS3_HUMAN
NC score	0.719303 (rank : 4)	θ value	3.27365e-34 (rank : 6)
Query Neighborhood Hits	29	Target Neighborhood Hits	97	Shared Neighborhood Hits	12
SwissProt Accessions	Q70JA7, Q76L22, Q86Y52	Gene names	CSS3, CHSY2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 3 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (Chondroitin synthase 2) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II) (Carbohydrate synthase 2).

CHSS1_HUMAN
NC score	0.713684 (rank : 5)	θ value	4.568e-36 (rank : 5)
Query Neighborhood Hits	29	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q86X52, Q6UX38, Q7LFU5, Q9Y2J5	Gene names	CHSY1, CHSY, CSS1, KIAA0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase 1) (Chondroitin sulfate synthase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

CHSS1_MOUSE
NC score	0.711708 (rank : 6)	θ value	3.4976e-36 (rank : 4)
Query Neighborhood Hits	29	Target Neighborhood Hits	56	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZQ11	Gene names	Chsy1, Kiaa0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase) (Chondroitin sulfate synthase 1) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

CGAT2_HUMAN
NC score	0.526527 (rank : 7)	θ value	1.02475e-11 (rank : 7)
Query Neighborhood Hits	29	Target Neighborhood Hits	59	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N6G5, Q6MZJ5, Q6MZP6, Q8TCH4, Q9P1I6	Gene names	GALNACT2, CHGN2
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (GalNAcT-2) (beta4GalNAcT-2).

CGAT2_MOUSE
NC score	0.525779 (rank : 8)	θ value	2.98157e-11 (rank : 8)
Query Neighborhood Hits	29	Target Neighborhood Hits	61	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C1F4, Q6PAP6, Q8R5A2, Q9D2M1	Gene names	Galnact2, Chgn2
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (GalNAcT-2) (beta4GalNAcT-2).

CGAT1_MOUSE
NC score	0.513060 (rank : 9)	θ value	3.29651e-10 (rank : 9)
Query Neighborhood Hits	29	Target Neighborhood Hits	61	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BJQ9, Q3UZX6, Q8BWV9, Q8BZU7, Q8C195, Q8R0M6	Gene names	Galnact1, Chgn
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.174) (beta4GalNAcT-1).

CGAT1_HUMAN
NC score	0.509589 (rank : 10)	θ value	1.25267e-09 (rank : 10)
Query Neighborhood Hits	29	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TDX6, Q6P9G6, Q8IUF9, Q9NSQ7, Q9NUM9	Gene names	GALNACT1, CHGN
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.174) (beta4GalNAcT-1).

B4GN4_HUMAN
NC score	0.230277 (rank : 11)	θ value	0.0431538 (rank : 11)
Query Neighborhood Hits	29	Target Neighborhood Hits	131	Shared Neighborhood Hits	18
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

B4GN4_MOUSE
NC score	0.229030 (rank : 12)	θ value	0.0563607 (rank : 12)
Query Neighborhood Hits	29	Target Neighborhood Hits	129	Shared Neighborhood Hits	12
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

B4GN3_HUMAN
NC score	0.180529 (rank : 13)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	29	Target Neighborhood Hits	128	Shared Neighborhood Hits	11
SwissProt Accessions	Q6L9W6, Q6ZNC1, Q8N7T6	Gene names	B4GALNT3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

B4GN3_MOUSE
NC score	0.177322 (rank : 14)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	29	Target Neighborhood Hits	49	Shared Neighborhood Hits	9
SwissProt Accessions	Q6L8S8	Gene names	B4galnt3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

B3GLT_MOUSE
NC score	0.125856 (rank : 15)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	29	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHT6, Q0PCR7, Q149S5	Gene names	B3galtl, Gm1057
Domain Architecture	No domain graphic available
Description	Beta-1,3-glucosyltransferase (EC 2.4.1.-) (Beta3Glc-T) (Beta-3- glycosyltransferase-like).

B3GLT_HUMAN
NC score	0.117870 (rank : 16)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	29	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q6Y288, Q5W0H2, Q6NUI3	Gene names	B3GALTL, B3GTL
Domain Architecture	No domain graphic available
Description	Beta-1,3-glucosyltransferase (EC 2.4.1.-) (Beta3Glc-T) (Beta-3- glycosyltransferase-like).

RFNG_MOUSE
NC score	0.091069 (rank : 17)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	29	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	O09009	Gene names	Rfng
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase radical fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

LFNG_MOUSE
NC score	0.069934 (rank : 18)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	29	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	O09010, Q3U659, Q8K3F1, Q9DC10	Gene names	Lfng
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

RFNG_HUMAN
NC score	0.067528 (rank : 19)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	29	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y644, O00588	Gene names	RFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase radical fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

LFNG_HUMAN
NC score	0.059820 (rank : 20)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	29	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NES3, O00589, Q96C39, Q9UJW5	Gene names	LFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

KITM_MOUSE
NC score	0.027515 (rank : 21)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	29	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R088	Gene names	Tk2
Domain Architecture
Description	Thymidine kinase 2, mitochondrial precursor (EC 2.7.1.21) (Mt-TK).

CV019_HUMAN
NC score	0.024913 (rank : 22)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	29	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q13769, O60839, Q9UPZ5	Gene names	C22orf19, KIAA0983
Domain Architecture	No domain graphic available
Description	Protein C22orf19 (NF2/meningioma region protein pK1.3) (Placental protein 39.2).

ZFHX2_HUMAN
NC score	0.024152 (rank : 23)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	29	Target Neighborhood Hits	1178	Shared Neighborhood Hits	10
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

GAK12_HUMAN
NC score	0.023708 (rank : 24)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	29	Target Neighborhood Hits	374	Shared Neighborhood Hits	12
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

G3ST3_MOUSE
NC score	0.021262 (rank : 25)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	29	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P61315	Gene names	Gal3st3
Domain Architecture	No domain graphic available
Description	Galactose-3-O-sulfotransferase 3 (EC 2.8.2.-) (Galbeta1-3GalNAc 3'- sulfotransferase) (Beta-galactose-3-O-sulfotransferase 3).

GAK4_HUMAN
NC score	0.019601 (rank : 26)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	29	Target Neighborhood Hits	415	Shared Neighborhood Hits	11
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
NC score	0.019587 (rank : 27)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	29	Target Neighborhood Hits	409	Shared Neighborhood Hits	11
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
NC score	0.019528 (rank : 28)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	29	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK5_HUMAN
NC score	0.019438 (rank : 29)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	29	Target Neighborhood Hits	429	Shared Neighborhood Hits	10
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
NC score	0.019346 (rank : 30)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	29	Target Neighborhood Hits	392	Shared Neighborhood Hits	10
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

TRI66_MOUSE
NC score	0.015340 (rank : 31)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	29	Target Neighborhood Hits	491	Shared Neighborhood Hits	9
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

NKX22_HUMAN
NC score	0.013558 (rank : 32)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	29	Target Neighborhood Hits	342	Shared Neighborhood Hits	4
SwissProt Accessions	O95096	Gene names	NKX2-2, NKX2.2, NKX2B
Domain Architecture
Description	Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B).

XKR7_HUMAN
NC score	0.010337 (rank : 33)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	29	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q5GH72, Q9NUG5	Gene names	XKR7, C20orf159, XRG7
Domain Architecture	No domain graphic available
Description	XK-related protein 7.

TSH1_HUMAN
NC score	0.009850 (rank : 34)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	29	Target Neighborhood Hits	558	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

TSH1_MOUSE
NC score	0.009535 (rank : 35)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	29	Target Neighborhood Hits	675	Shared Neighborhood Hits	3
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

MCLN2_MOUSE
NC score	0.006915 (rank : 36)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	29	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

PRRT3_HUMAN
NC score	0.005702 (rank : 37)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	29	Target Neighborhood Hits	998	Shared Neighborhood Hits	7
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.