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Network neighborhood for query Sequence : CHGUT_HUMAN

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CHGUT_HUMAN
SwissProt Accessions	Q9P2E5, Q6P2I4, Q6UXD2	Gene names	CSGLCAT, KIAA1402
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate glucuronyltransferase (EC 2.4.1.226) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (Chondroitin glucuronyltransferase II) (CSGlcA-T).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CHGUT_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P2E5, Q6P2I4, Q6UXD2	Gene names	CSGLCAT, KIAA1402
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate glucuronyltransferase (EC 2.4.1.226) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (Chondroitin glucuronyltransferase II) (CSGlcA-T).

CHSS2_HUMAN
θ value	0 (rank : 2)	NC score	0.978275 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZ52, Q6UXD6, Q7L4G1, Q9H0F8, Q9H618	Gene names	CSS2, CHPF
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl- proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase) (Chondroitin-polymerizing factor).

CHSS2_MOUSE
θ value	0 (rank : 3)	NC score	0.979104 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q6IQX7	Gene names	Css2, D1Bwg1363e
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl- proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase).

CHSS3_HUMAN
θ value	1.28434e-38 (rank : 4)	NC score	0.718281 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	97	Shared Neighborhood Hits	20
SwissProt Accessions	Q70JA7, Q76L22, Q86Y52	Gene names	CSS3, CHSY2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 3 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (Chondroitin synthase 2) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II) (Carbohydrate synthase 2).

CHSS1_HUMAN
θ value	1.98606e-31 (rank : 5)	NC score	0.710660 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	51	Shared Neighborhood Hits	20
SwissProt Accessions	Q86X52, Q6UX38, Q7LFU5, Q9Y2J5	Gene names	CHSY1, CHSY, CSS1, KIAA0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase 1) (Chondroitin sulfate synthase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

CHSS1_MOUSE
θ value	1.98606e-31 (rank : 6)	NC score	0.710797 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZQ11	Gene names	Chsy1, Kiaa0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase) (Chondroitin sulfate synthase 1) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

CGAT2_HUMAN
θ value	7.59969e-07 (rank : 7)	NC score	0.476460 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	59	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N6G5, Q6MZJ5, Q6MZP6, Q8TCH4, Q9P1I6	Gene names	GALNACT2, CHGN2
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (GalNAcT-2) (beta4GalNAcT-2).

CGAT2_MOUSE
θ value	7.59969e-07 (rank : 8)	NC score	0.475924 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	61	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C1F4, Q6PAP6, Q8R5A2, Q9D2M1	Gene names	Galnact2, Chgn2
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (GalNAcT-2) (beta4GalNAcT-2).

CGAT1_HUMAN
θ value	3.77169e-06 (rank : 9)	NC score	0.460663 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TDX6, Q6P9G6, Q8IUF9, Q9NSQ7, Q9NUM9	Gene names	GALNACT1, CHGN
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.174) (beta4GalNAcT-1).

RFNG_MOUSE
θ value	3.77169e-06 (rank : 10)	NC score	0.213235 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	O09009	Gene names	Rfng
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase radical fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

CGAT1_MOUSE
θ value	1.87187e-05 (rank : 11)	NC score	0.462973 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	61	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BJQ9, Q3UZX6, Q8BWV9, Q8BZU7, Q8C195, Q8R0M6	Gene names	Galnact1, Chgn
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.174) (beta4GalNAcT-1).

RFNG_HUMAN
θ value	0.00869519 (rank : 12)	NC score	0.183669 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y644, O00588	Gene names	RFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase radical fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

MFNG_HUMAN
θ value	0.0736092 (rank : 13)	NC score	0.144751 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	O00587, O43730	Gene names	MFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase manic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

CNTRB_MOUSE
θ value	0.125558 (rank : 14)	NC score	0.019529 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	1029	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

LFNG_MOUSE
θ value	0.163984 (rank : 15)	NC score	0.179639 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	O09010, Q3U659, Q8K3F1, Q9DC10	Gene names	Lfng
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

B4GN4_MOUSE
θ value	0.365318 (rank : 16)	NC score	0.196042 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	129	Shared Neighborhood Hits	12
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

LFNG_HUMAN
θ value	0.47712 (rank : 17)	NC score	0.169449 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NES3, O00589, Q96C39, Q9UJW5	Gene names	LFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

B3GLT_HUMAN
θ value	0.62314 (rank : 18)	NC score	0.192484 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q6Y288, Q5W0H2, Q6NUI3	Gene names	B3GALTL, B3GTL
Domain Architecture	No domain graphic available
Description	Beta-1,3-glucosyltransferase (EC 2.4.1.-) (Beta3Glc-T) (Beta-3- glycosyltransferase-like).

B3GLT_MOUSE
θ value	0.62314 (rank : 19)	NC score	0.200168 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHT6, Q0PCR7, Q149S5	Gene names	B3galtl, Gm1057
Domain Architecture	No domain graphic available
Description	Beta-1,3-glucosyltransferase (EC 2.4.1.-) (Beta3Glc-T) (Beta-3- glycosyltransferase-like).

PON2_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.031747 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q15165, O15114, O15115, O75856, Q86YL0	Gene names	PON2
Domain Architecture
Description	Serum paraoxonase/arylesterase 2 (EC 3.1.1.2) (EC 3.1.8.1) (PON 2) (Serum aryldialkylphosphatase 2) (A-esterase 2) (Aromatic esterase 2).

SRCA_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.018570 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	380	Shared Neighborhood Hits	2
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

PON2_MOUSE
θ value	1.81305 (rank : 22)	NC score	0.028904 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q62086, Q8CFK3	Gene names	Pon2
Domain Architecture
Description	Serum paraoxonase/arylesterase 2 (EC 3.1.1.2) (EC 3.1.8.1) (PON 2) (Serum aryldialkylphosphatase 2) (A-esterase 2) (Aromatic esterase 2).

MFNG_MOUSE
θ value	3.0926 (rank : 23)	NC score	0.143954 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	13	Shared Neighborhood Hits	12
SwissProt Accessions	O09008	Gene names	Mfng
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase manic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

B4GN3_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.157892 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	128	Shared Neighborhood Hits	10
SwissProt Accessions	Q6L9W6, Q6ZNC1, Q8N7T6	Gene names	B4GALNT3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

BT1A1_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.006359 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	322	Shared Neighborhood Hits	3
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

KIF11_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.003591 (rank : 35)
Query Neighborhood Hits	34	Target Neighborhood Hits	583	Shared Neighborhood Hits	3
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

LYAG_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.010345 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P10253, Q14351, Q16302	Gene names	GAA
Domain Architecture
Description	Lysosomal alpha-glucosidase precursor (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Contains: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase].

BT1A1_MOUSE
θ value	6.88961 (rank : 28)	NC score	0.006082 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	252	Shared Neighborhood Hits	3
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

MLL3_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.003533 (rank : 36)
Query Neighborhood Hits	34	Target Neighborhood Hits	1644	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PSMF1_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.015443 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

SMBT2_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.008691 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q5DTW2, Q80VG7	Gene names	Sfmbt2, Kiaa1617
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 2.

ANGL7_MOUSE
θ value	8.99809 (rank : 32)	NC score	0.003863 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1Q3	Gene names	Angptl7
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7).

SAPS2_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.007231 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	O75170, Q9UGB9	Gene names	SAPS2, KIAA0685
Domain Architecture
Description	SAPS domain family member 2.

TNAP3_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.009125 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	P21580, Q5VXQ7, Q9NSR6	Gene names	TNFAIP3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

B4GN3_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.152577 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	49	Shared Neighborhood Hits	9
SwissProt Accessions	Q6L8S8	Gene names	B4galnt3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

B4GN4_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.190445 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	131	Shared Neighborhood Hits	12
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

Hits sorted by NC score

CHGUT_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P2E5, Q6P2I4, Q6UXD2	Gene names	CSGLCAT, KIAA1402
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate glucuronyltransferase (EC 2.4.1.226) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (Chondroitin glucuronyltransferase II) (CSGlcA-T).

CHSS2_MOUSE
NC score	0.979104 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q6IQX7	Gene names	Css2, D1Bwg1363e
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl- proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase).

CHSS2_HUMAN
NC score	0.978275 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZ52, Q6UXD6, Q7L4G1, Q9H0F8, Q9H618	Gene names	CSS2, CHPF
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl- proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase) (Chondroitin-polymerizing factor).

CHSS3_HUMAN
NC score	0.718281 (rank : 4)	θ value	1.28434e-38 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	97	Shared Neighborhood Hits	20
SwissProt Accessions	Q70JA7, Q76L22, Q86Y52	Gene names	CSS3, CHSY2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 3 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (Chondroitin synthase 2) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II) (Carbohydrate synthase 2).

CHSS1_MOUSE
NC score	0.710797 (rank : 5)	θ value	1.98606e-31 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZQ11	Gene names	Chsy1, Kiaa0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase) (Chondroitin sulfate synthase 1) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

CHSS1_HUMAN
NC score	0.710660 (rank : 6)	θ value	1.98606e-31 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	51	Shared Neighborhood Hits	20
SwissProt Accessions	Q86X52, Q6UX38, Q7LFU5, Q9Y2J5	Gene names	CHSY1, CHSY, CSS1, KIAA0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase 1) (Chondroitin sulfate synthase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

CGAT2_HUMAN
NC score	0.476460 (rank : 7)	θ value	7.59969e-07 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	59	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N6G5, Q6MZJ5, Q6MZP6, Q8TCH4, Q9P1I6	Gene names	GALNACT2, CHGN2
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (GalNAcT-2) (beta4GalNAcT-2).

CGAT2_MOUSE
NC score	0.475924 (rank : 8)	θ value	7.59969e-07 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	61	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C1F4, Q6PAP6, Q8R5A2, Q9D2M1	Gene names	Galnact2, Chgn2
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (GalNAcT-2) (beta4GalNAcT-2).

CGAT1_MOUSE
NC score	0.462973 (rank : 9)	θ value	1.87187e-05 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	61	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BJQ9, Q3UZX6, Q8BWV9, Q8BZU7, Q8C195, Q8R0M6	Gene names	Galnact1, Chgn
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.174) (beta4GalNAcT-1).

CGAT1_HUMAN
NC score	0.460663 (rank : 10)	θ value	3.77169e-06 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	69	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TDX6, Q6P9G6, Q8IUF9, Q9NSQ7, Q9NUM9	Gene names	GALNACT1, CHGN
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.174) (beta4GalNAcT-1).

RFNG_MOUSE
NC score	0.213235 (rank : 11)	θ value	3.77169e-06 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	O09009	Gene names	Rfng
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase radical fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

B3GLT_MOUSE
NC score	0.200168 (rank : 12)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHT6, Q0PCR7, Q149S5	Gene names	B3galtl, Gm1057
Domain Architecture	No domain graphic available
Description	Beta-1,3-glucosyltransferase (EC 2.4.1.-) (Beta3Glc-T) (Beta-3- glycosyltransferase-like).

B4GN4_MOUSE
NC score	0.196042 (rank : 13)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	129	Shared Neighborhood Hits	12
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

B3GLT_HUMAN
NC score	0.192484 (rank : 14)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q6Y288, Q5W0H2, Q6NUI3	Gene names	B3GALTL, B3GTL
Domain Architecture	No domain graphic available
Description	Beta-1,3-glucosyltransferase (EC 2.4.1.-) (Beta3Glc-T) (Beta-3- glycosyltransferase-like).

B4GN4_HUMAN
NC score	0.190445 (rank : 15)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	34	Target Neighborhood Hits	131	Shared Neighborhood Hits	12
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

RFNG_HUMAN
NC score	0.183669 (rank : 16)	θ value	0.00869519 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y644, O00588	Gene names	RFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase radical fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

LFNG_MOUSE
NC score	0.179639 (rank : 17)	θ value	0.163984 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	O09010, Q3U659, Q8K3F1, Q9DC10	Gene names	Lfng
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

LFNG_HUMAN
NC score	0.169449 (rank : 18)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NES3, O00589, Q96C39, Q9UJW5	Gene names	LFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

B4GN3_HUMAN
NC score	0.157892 (rank : 19)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	128	Shared Neighborhood Hits	10
SwissProt Accessions	Q6L9W6, Q6ZNC1, Q8N7T6	Gene names	B4GALNT3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

B4GN3_MOUSE
NC score	0.152577 (rank : 20)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	34	Target Neighborhood Hits	49	Shared Neighborhood Hits	9
SwissProt Accessions	Q6L8S8	Gene names	B4galnt3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

MFNG_HUMAN
NC score	0.144751 (rank : 21)	θ value	0.0736092 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	O00587, O43730	Gene names	MFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase manic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

MFNG_MOUSE
NC score	0.143954 (rank : 22)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	13	Shared Neighborhood Hits	12
SwissProt Accessions	O09008	Gene names	Mfng
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase manic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

PON2_HUMAN
NC score	0.031747 (rank : 23)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q15165, O15114, O15115, O75856, Q86YL0	Gene names	PON2
Domain Architecture
Description	Serum paraoxonase/arylesterase 2 (EC 3.1.1.2) (EC 3.1.8.1) (PON 2) (Serum aryldialkylphosphatase 2) (A-esterase 2) (Aromatic esterase 2).

PON2_MOUSE
NC score	0.028904 (rank : 24)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q62086, Q8CFK3	Gene names	Pon2
Domain Architecture
Description	Serum paraoxonase/arylesterase 2 (EC 3.1.1.2) (EC 3.1.8.1) (PON 2) (Serum aryldialkylphosphatase 2) (A-esterase 2) (Aromatic esterase 2).

CNTRB_MOUSE
NC score	0.019529 (rank : 25)	θ value	0.125558 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	1029	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

SRCA_HUMAN
NC score	0.018570 (rank : 26)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	380	Shared Neighborhood Hits	2
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

PSMF1_MOUSE
NC score	0.015443 (rank : 27)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BHL8, Q8C0G9	Gene names	Psmf1
Domain Architecture	No domain graphic available
Description	Proteasome inhibitor PI31 subunit.

LYAG_HUMAN
NC score	0.010345 (rank : 28)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P10253, Q14351, Q16302	Gene names	GAA
Domain Architecture
Description	Lysosomal alpha-glucosidase precursor (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Contains: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase].

TNAP3_HUMAN
NC score	0.009125 (rank : 29)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	P21580, Q5VXQ7, Q9NSR6	Gene names	TNFAIP3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

SMBT2_MOUSE
NC score	0.008691 (rank : 30)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q5DTW2, Q80VG7	Gene names	Sfmbt2, Kiaa1617
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 2.

SAPS2_HUMAN
NC score	0.007231 (rank : 31)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	O75170, Q9UGB9	Gene names	SAPS2, KIAA0685
Domain Architecture
Description	SAPS domain family member 2.

BT1A1_HUMAN
NC score	0.006359 (rank : 32)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	322	Shared Neighborhood Hits	3
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_MOUSE
NC score	0.006082 (rank : 33)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	252	Shared Neighborhood Hits	3
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

ANGL7_MOUSE
NC score	0.003863 (rank : 34)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1Q3	Gene names	Angptl7
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7).

KIF11_HUMAN
NC score	0.003591 (rank : 35)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	583	Shared Neighborhood Hits	3
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

MLL3_HUMAN
NC score	0.003533 (rank : 36)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	1644	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).