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Network neighborhood for query Sequence : PON2_HUMAN

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PON2_HUMAN
SwissProt Accessions	Q15165, O15114, O15115, O75856, Q86YL0	Gene names	PON2
Domain Architecture
Description	Serum paraoxonase/arylesterase 2 (EC 3.1.1.2) (EC 3.1.8.1) (PON 2) (Serum aryldialkylphosphatase 2) (A-esterase 2) (Aromatic esterase 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PON2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q15165, O15114, O15115, O75856, Q86YL0	Gene names	PON2
Domain Architecture
Description	Serum paraoxonase/arylesterase 2 (EC 3.1.1.2) (EC 3.1.8.1) (PON 2) (Serum aryldialkylphosphatase 2) (A-esterase 2) (Aromatic esterase 2).

PON2_MOUSE
θ value	1.66487e-179 (rank : 2)	NC score	0.999060 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	Q62086, Q8CFK3	Gene names	Pon2
Domain Architecture
Description	Serum paraoxonase/arylesterase 2 (EC 3.1.1.2) (EC 3.1.8.1) (PON 2) (Serum aryldialkylphosphatase 2) (A-esterase 2) (Aromatic esterase 2).

PON1_HUMAN
θ value	1.4755e-135 (rank : 3)	NC score	0.994083 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	P27169, Q16052	Gene names	PON1, PON
Domain Architecture
Description	Serum paraoxonase/arylesterase 1 (EC 3.1.1.2) (EC 3.1.8.1) (PON 1) (Serum aryldialkylphosphatase 1) (A-esterase 1) (Aromatic esterase 1) (K-45).

PON1_MOUSE
θ value	8.09639e-134 (rank : 4)	NC score	0.994214 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P52430	Gene names	Pon1, Pon
Domain Architecture
Description	Serum paraoxonase/arylesterase 1 (EC 3.1.1.2) (EC 3.1.8.1) (PON 1) (Serum aryldialkylphosphatase 1) (A-esterase 1) (Aromatic esterase 1).

PON3_HUMAN
θ value	8.9516e-133 (rank : 5)	NC score	0.994081 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q15166, O75855, O76060, Q6IRU9, Q8IX97, Q9BZH9	Gene names	PON3
Domain Architecture
Description	Serum paraoxonase/lactonase 3 (EC 3.1.1.-).

PON3_MOUSE
θ value	6.00439e-129 (rank : 6)	NC score	0.991103 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q62087, Q8C2I7	Gene names	Pon3
Domain Architecture
Description	Serum paraoxonase/lactonase 3 (EC 3.1.1.-).

CHGUT_HUMAN
θ value	0.813845 (rank : 7)	NC score	0.031747 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2E5, Q6P2I4, Q6UXD2	Gene names	CSGLCAT, KIAA1402
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate glucuronyltransferase (EC 2.4.1.226) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (Chondroitin glucuronyltransferase II) (CSGlcA-T).

AP2B1_HUMAN
θ value	1.06291 (rank : 8)	NC score	0.022793 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	P63010, P21851, Q96J19	Gene names	AP2B1, CLAPB1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

AP2B1_MOUSE
θ value	1.06291 (rank : 9)	NC score	0.022795 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBG3, Q80XJ4	Gene names	Ap2b1, Clapb1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

SNX19_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.016692 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	Q92543	Gene names	SNX19, KIAA0254
Domain Architecture
Description	Sorting nexin-19.

APMAP_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.024343 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D7N9, Q3U4F4	Gene names	Apmap
Domain Architecture
Description	Adipocyte plasma membrane-associated protein (Protein DD16).

CRNL1_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.008618 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZJ0, Q5JY64, Q8WYI5, Q9BZI9, Q9BZJ1, Q9BZJ2, Q9GZW7, Q9H8F8, Q9NQH5, Q9NYD8	Gene names	CRNKL1, CRN
Domain Architecture
Description	Crooked neck-like protein 1 (Crooked neck homolog) (hCrn).

Hits sorted by NC score

PON2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q15165, O15114, O15115, O75856, Q86YL0	Gene names	PON2
Domain Architecture
Description	Serum paraoxonase/arylesterase 2 (EC 3.1.1.2) (EC 3.1.8.1) (PON 2) (Serum aryldialkylphosphatase 2) (A-esterase 2) (Aromatic esterase 2).

PON2_MOUSE
NC score	0.999060 (rank : 2)	θ value	1.66487e-179 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	7	Shared Neighborhood Hits	7
SwissProt Accessions	Q62086, Q8CFK3	Gene names	Pon2
Domain Architecture
Description	Serum paraoxonase/arylesterase 2 (EC 3.1.1.2) (EC 3.1.8.1) (PON 2) (Serum aryldialkylphosphatase 2) (A-esterase 2) (Aromatic esterase 2).

PON1_MOUSE
NC score	0.994214 (rank : 3)	θ value	8.09639e-134 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	8	Shared Neighborhood Hits	6
SwissProt Accessions	P52430	Gene names	Pon1, Pon
Domain Architecture
Description	Serum paraoxonase/arylesterase 1 (EC 3.1.1.2) (EC 3.1.8.1) (PON 1) (Serum aryldialkylphosphatase 1) (A-esterase 1) (Aromatic esterase 1).

PON1_HUMAN
NC score	0.994083 (rank : 4)	θ value	1.4755e-135 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	P27169, Q16052	Gene names	PON1, PON
Domain Architecture
Description	Serum paraoxonase/arylesterase 1 (EC 3.1.1.2) (EC 3.1.8.1) (PON 1) (Serum aryldialkylphosphatase 1) (A-esterase 1) (Aromatic esterase 1) (K-45).

PON3_HUMAN
NC score	0.994081 (rank : 5)	θ value	8.9516e-133 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q15166, O75855, O76060, Q6IRU9, Q8IX97, Q9BZH9	Gene names	PON3
Domain Architecture
Description	Serum paraoxonase/lactonase 3 (EC 3.1.1.-).

PON3_MOUSE
NC score	0.991103 (rank : 6)	θ value	6.00439e-129 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q62087, Q8C2I7	Gene names	Pon3
Domain Architecture
Description	Serum paraoxonase/lactonase 3 (EC 3.1.1.-).

CHGUT_HUMAN
NC score	0.031747 (rank : 7)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2E5, Q6P2I4, Q6UXD2	Gene names	CSGLCAT, KIAA1402
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate glucuronyltransferase (EC 2.4.1.226) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (Chondroitin glucuronyltransferase II) (CSGlcA-T).

APMAP_MOUSE
NC score	0.024343 (rank : 8)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D7N9, Q3U4F4	Gene names	Apmap
Domain Architecture
Description	Adipocyte plasma membrane-associated protein (Protein DD16).

AP2B1_MOUSE
NC score	0.022795 (rank : 9)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBG3, Q80XJ4	Gene names	Ap2b1, Clapb1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

AP2B1_HUMAN
NC score	0.022793 (rank : 10)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	P63010, P21851, Q96J19	Gene names	AP2B1, CLAPB1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

SNX19_HUMAN
NC score	0.016692 (rank : 11)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	Q92543	Gene names	SNX19, KIAA0254
Domain Architecture
Description	Sorting nexin-19.

CRNL1_HUMAN
NC score	0.008618 (rank : 12)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZJ0, Q5JY64, Q8WYI5, Q9BZI9, Q9BZJ1, Q9BZJ2, Q9GZW7, Q9H8F8, Q9NQH5, Q9NYD8	Gene names	CRNKL1, CRN
Domain Architecture
Description	Crooked neck-like protein 1 (Crooked neck homolog) (hCrn).