Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : DNL3_MOUSE

For an explanation of this page, click here

DNL3_MOUSE
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DNL3_HUMAN
θ value	0 (rank : 1)	NC score	0.994632 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	49	Shared Neighborhood Hits	22
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

DNL3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

DNL1_HUMAN
θ value	2.04573e-44 (rank : 3)	NC score	0.716456 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	216	Shared Neighborhood Hits	9
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

DNL1_MOUSE
θ value	2.50074e-42 (rank : 4)	NC score	0.739839 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	110	Shared Neighborhood Hits	10
SwissProt Accessions	P37913	Gene names	Lig1, Lig-1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

DNL4_HUMAN
θ value	6.59618e-35 (rank : 5)	NC score	0.715810 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P49917, Q8IY66, Q8TEU5	Gene names	LIG4
Domain Architecture
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

DNL4_MOUSE
θ value	1.52067e-31 (rank : 6)	NC score	0.707095 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BTF7, Q3UG76	Gene names	Lig4
Domain Architecture	No domain graphic available
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

PARP1_MOUSE
θ value	7.59969e-07 (rank : 7)	NC score	0.205467 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	102	Shared Neighborhood Hits	6
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

PARP1_HUMAN
θ value	1.29631e-06 (rank : 8)	NC score	0.201646 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

CAC1F_HUMAN
θ value	0.813845 (rank : 9)	NC score	0.033468 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	141	Shared Neighborhood Hits	9
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_MOUSE
θ value	0.813845 (rank : 10)	NC score	0.033594 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

KLH20_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.015379 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	192	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2M5, Q5TZF2, Q9H457	Gene names	KLHL20, KLEIP
Domain Architecture
Description	Kelch-like protein 20 (Kelch-like ECT2-interacting protein) (Kelch- like protein X).

KLH20_MOUSE
θ value	1.38821 (rank : 12)	NC score	0.015376 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	192	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VCK5, Q8BWA2	Gene names	Klhl20, Kleip
Domain Architecture	No domain graphic available
Description	Kelch-like protein 20 (Kelch-like ECT2-interacting protein).

PPRB_MOUSE
θ value	1.38821 (rank : 13)	NC score	0.036729 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	354	Shared Neighborhood Hits	5
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

GOGA3_MOUSE
θ value	1.81305 (rank : 14)	NC score	0.014133 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	1437	Shared Neighborhood Hits	13
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

INCE_HUMAN
θ value	1.81305 (rank : 15)	NC score	0.014841 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	978	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

ANK2_HUMAN
θ value	2.36792 (rank : 16)	NC score	0.012531 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	1615	Shared Neighborhood Hits	11
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

NOL8_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.021663 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

PPRB_HUMAN
θ value	2.36792 (rank : 18)	NC score	0.035835 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	311	Shared Neighborhood Hits	5
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

TMCC1_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.023011 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	337	Shared Neighborhood Hits	8
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

RBCC1_MOUSE
θ value	3.0926 (rank : 20)	NC score	0.012077 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	1048	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

TMCC1_MOUSE
θ value	3.0926 (rank : 21)	NC score	0.022433 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	315	Shared Neighborhood Hits	8
SwissProt Accessions	Q69ZZ6, Q8CEF4	Gene names	Tmcc1, Kiaa0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

XRCC1_MOUSE
θ value	3.0926 (rank : 22)	NC score	0.045884 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ZN638_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.018675 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	343	Shared Neighborhood Hits	4
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

BRCA1_MOUSE
θ value	4.03905 (rank : 24)	NC score	0.013205 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	436	Shared Neighborhood Hits	4
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

DMD_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.007736 (rank : 40)
Query Neighborhood Hits	37	Target Neighborhood Hits	1111	Shared Neighborhood Hits	9
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

TGON2_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.025729 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	1037	Shared Neighborhood Hits	10
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

DCX_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.010954 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	O43602, O43911	Gene names	DCX, DBCN, LISX
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

KLHL6_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.012694 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	192	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ60, Q8N5I1, Q8N892	Gene names	KLHL6
Domain Architecture
Description	Kelch-like protein 6.

CAC1C_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.025473 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1C_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.025280 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	130	Shared Neighborhood Hits	7
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1D_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.025251 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

PLEC1_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.008428 (rank : 39)
Query Neighborhood Hits	37	Target Neighborhood Hits	1326	Shared Neighborhood Hits	11
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

GOGA3_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.009955 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	1317	Shared Neighborhood Hits	11
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

KEAP1_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.011523 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	182	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z2X8	Gene names	Keap1
Domain Architecture
Description	Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2).

KI67_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.021140 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	581	Shared Neighborhood Hits	10
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

MELPH_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.010837 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

NTBP1_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.013452 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	171	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T7V8, Q49A22, Q6P1P9, Q9HAE6, Q9Y350	Gene names	SCYL1BP1, NTKLBP1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (hNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

PARP2_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.069124 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

PARP2_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.069153 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

PARP3_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.067042 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

Hits sorted by NC score

DNL3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

DNL3_HUMAN
NC score	0.994632 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	49	Shared Neighborhood Hits	22
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

DNL1_MOUSE
NC score	0.739839 (rank : 3)	θ value	2.50074e-42 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	110	Shared Neighborhood Hits	10
SwissProt Accessions	P37913	Gene names	Lig1, Lig-1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

DNL1_HUMAN
NC score	0.716456 (rank : 4)	θ value	2.04573e-44 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	216	Shared Neighborhood Hits	9
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

DNL4_HUMAN
NC score	0.715810 (rank : 5)	θ value	6.59618e-35 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P49917, Q8IY66, Q8TEU5	Gene names	LIG4
Domain Architecture
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

DNL4_MOUSE
NC score	0.707095 (rank : 6)	θ value	1.52067e-31 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BTF7, Q3UG76	Gene names	Lig4
Domain Architecture	No domain graphic available
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

PARP1_MOUSE
NC score	0.205467 (rank : 7)	θ value	7.59969e-07 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	102	Shared Neighborhood Hits	6
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

PARP1_HUMAN
NC score	0.201646 (rank : 8)	θ value	1.29631e-06 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

PARP2_MOUSE
NC score	0.069153 (rank : 9)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	37	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

PARP2_HUMAN
NC score	0.069124 (rank : 10)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

PARP3_HUMAN
NC score	0.067042 (rank : 11)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	37	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

XRCC1_MOUSE
NC score	0.045884 (rank : 12)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

PPRB_MOUSE
NC score	0.036729 (rank : 13)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	354	Shared Neighborhood Hits	5
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

PPRB_HUMAN
NC score	0.035835 (rank : 14)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	311	Shared Neighborhood Hits	5
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

CAC1F_MOUSE
NC score	0.033594 (rank : 15)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_HUMAN
NC score	0.033468 (rank : 16)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	141	Shared Neighborhood Hits	9
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

TGON2_HUMAN
NC score	0.025729 (rank : 17)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	1037	Shared Neighborhood Hits	10
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CAC1C_HUMAN
NC score	0.025473 (rank : 18)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1C_MOUSE
NC score	0.025280 (rank : 19)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	130	Shared Neighborhood Hits	7
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1D_HUMAN
NC score	0.025251 (rank : 20)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

TMCC1_HUMAN
NC score	0.023011 (rank : 21)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	337	Shared Neighborhood Hits	8
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

TMCC1_MOUSE
NC score	0.022433 (rank : 22)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	315	Shared Neighborhood Hits	8
SwissProt Accessions	Q69ZZ6, Q8CEF4	Gene names	Tmcc1, Kiaa0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

NOL8_HUMAN
NC score	0.021663 (rank : 23)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

KI67_HUMAN
NC score	0.021140 (rank : 24)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	581	Shared Neighborhood Hits	10
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

ZN638_HUMAN
NC score	0.018675 (rank : 25)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	343	Shared Neighborhood Hits	4
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

KLH20_HUMAN
NC score	0.015379 (rank : 26)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	192	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2M5, Q5TZF2, Q9H457	Gene names	KLHL20, KLEIP
Domain Architecture
Description	Kelch-like protein 20 (Kelch-like ECT2-interacting protein) (Kelch- like protein X).

KLH20_MOUSE
NC score	0.015376 (rank : 27)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	192	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VCK5, Q8BWA2	Gene names	Klhl20, Kleip
Domain Architecture	No domain graphic available
Description	Kelch-like protein 20 (Kelch-like ECT2-interacting protein).

INCE_HUMAN
NC score	0.014841 (rank : 28)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	978	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

GOGA3_MOUSE
NC score	0.014133 (rank : 29)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	1437	Shared Neighborhood Hits	13
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

NTBP1_HUMAN
NC score	0.013452 (rank : 30)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	171	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T7V8, Q49A22, Q6P1P9, Q9HAE6, Q9Y350	Gene names	SCYL1BP1, NTKLBP1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (hNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

BRCA1_MOUSE
NC score	0.013205 (rank : 31)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	436	Shared Neighborhood Hits	4
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

KLHL6_HUMAN
NC score	0.012694 (rank : 32)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	192	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ60, Q8N5I1, Q8N892	Gene names	KLHL6
Domain Architecture
Description	Kelch-like protein 6.

ANK2_HUMAN
NC score	0.012531 (rank : 33)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	1615	Shared Neighborhood Hits	11
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

RBCC1_MOUSE
NC score	0.012077 (rank : 34)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	1048	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

KEAP1_MOUSE
NC score	0.011523 (rank : 35)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	182	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z2X8	Gene names	Keap1
Domain Architecture
Description	Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2).

DCX_HUMAN
NC score	0.010954 (rank : 36)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	O43602, O43911	Gene names	DCX, DBCN, LISX
Domain Architecture
Description	Neuronal migration protein doublecortin (Lissencephalin-X) (Lis-X) (Doublin).

MELPH_MOUSE
NC score	0.010837 (rank : 37)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

GOGA3_HUMAN
NC score	0.009955 (rank : 38)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	1317	Shared Neighborhood Hits	11
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

PLEC1_HUMAN
NC score	0.008428 (rank : 39)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	1326	Shared Neighborhood Hits	11
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

DMD_MOUSE
NC score	0.007736 (rank : 40)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	1111	Shared Neighborhood Hits	9
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.