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Network neighborhood for query Sequence : PARP3_HUMAN

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PARP3_HUMAN
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PARP3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

PARP2_MOUSE
θ value	1.60597e-73 (rank : 2)	NC score	0.923806 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

PARP2_HUMAN
θ value	3.70236e-70 (rank : 3)	NC score	0.926769 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	33	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

PARP1_HUMAN
θ value	6.32992e-62 (rank : 4)	NC score	0.887538 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

PARP1_MOUSE
θ value	4.53632e-60 (rank : 5)	NC score	0.876410 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

PARP4_HUMAN
θ value	1.09485e-13 (rank : 6)	NC score	0.538458 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	93	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

PAR15_HUMAN
θ value	0.00390308 (rank : 7)	NC score	0.146782 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q460N3, Q8N1K3	Gene names	PARP15, BAL3
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 15 (EC 2.4.2.30) (PARP-15) (B-aggressive lymphoma protein 3).

PAR14_HUMAN
θ value	0.00665767 (rank : 8)	NC score	0.133939 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q460N5, Q460N4, Q8J027, Q9H9X9, Q9NV60, Q9ULF2	Gene names	PARP14, BAL2, KIAA1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (B aggressive lymphoma protein 2).

TNKS1_HUMAN
θ value	0.00665767 (rank : 9)	NC score	0.081138 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	477	Shared Neighborhood Hits	13
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ZCC2_HUMAN
θ value	0.00665767 (rank : 10)	NC score	0.137334 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

PARPT_MOUSE
θ value	0.00869519 (rank : 11)	NC score	0.153664 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

PAR14_MOUSE
θ value	0.0113563 (rank : 12)	NC score	0.140620 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

TNKS2_HUMAN
θ value	0.0193708 (rank : 13)	NC score	0.078865 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	361	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

BPHL_HUMAN
θ value	0.163984 (rank : 14)	NC score	0.062228 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q86WA6, Q00306, Q13855	Gene names	BPHL
Domain Architecture
Description	Valacyclovir hydrolase precursor (EC 3.1.-.-) (VACVase) (Biphenyl hydrolase-like protein) (Biphenyl hydrolase-related protein) (Bph-rp) (Breast epithelial mucin-associated antigen) (MCNAA).

PARP6_HUMAN
θ value	0.21417 (rank : 15)	NC score	0.144574 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q2NL67, Q9H7C5, Q9H9X6, Q9HAF3, Q9NPS6, Q9UFG4	Gene names	PARP6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PARP6_MOUSE
θ value	0.21417 (rank : 16)	NC score	0.144517 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P6P7, Q8BVW1	Gene names	Parp6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

HDAC8_MOUSE
θ value	0.62314 (rank : 17)	NC score	0.023768 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VH37, Q3V270, Q9D0K6	Gene names	Hdac8
Domain Architecture
Description	Histone deacetylase 8 (HD8).

KERA_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.014515 (rank : 34)
Query Neighborhood Hits	30	Target Neighborhood Hits	275	Shared Neighborhood Hits	3
SwissProt Accessions	O60938	Gene names	KERA
Domain Architecture
Description	Keratocan precursor (KTN) (Keratan sulfate proteoglycan keratocan).

PARP8_HUMAN
θ value	1.38821 (rank : 19)	NC score	0.138226 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N3A8, Q3KRB7, Q6DHZ1, Q9H754	Gene names	PARP8
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).

PARP8_MOUSE
θ value	1.38821 (rank : 20)	NC score	0.137905 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UD82, Q3UDE4, Q3UDU5, Q8VCB5, Q9CYY3	Gene names	Parp8, D13Ertd275e
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).

KERA_MOUSE
θ value	3.0926 (rank : 21)	NC score	0.013020 (rank : 35)
Query Neighborhood Hits	30	Target Neighborhood Hits	264	Shared Neighborhood Hits	3
SwissProt Accessions	O35367	Gene names	Kera, Ktcn
Domain Architecture
Description	Keratocan precursor (KTN) (Keratan sulfate proteoglycan keratocan).

MACF1_MOUSE
θ value	3.0926 (rank : 22)	NC score	0.006323 (rank : 38)
Query Neighborhood Hits	30	Target Neighborhood Hits	1313	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

RASL1_MOUSE
θ value	3.0926 (rank : 23)	NC score	0.014855 (rank : 33)
Query Neighborhood Hits	30	Target Neighborhood Hits	148	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

XYLT2_HUMAN
θ value	5.27518 (rank : 24)	NC score	0.020580 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1B5, Q6UY41, Q86V00	Gene names	XYLT2, XT2
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 2 (EC 2.4.2.26) (Xylosyltransferase II) (xylT-II) (XT-II) (Peptide O-xylosyltransferase 1).

XYLT2_MOUSE
θ value	5.27518 (rank : 25)	NC score	0.020423 (rank : 31)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPL0, Q5SUY1, Q8K060	Gene names	Xylt2
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 2 (EC 2.4.2.26) (Xylosyltransferase II) (Peptide O- xylosyltransferase 2).

CC023_MOUSE
θ value	6.88961 (rank : 26)	NC score	0.016912 (rank : 32)
Query Neighborhood Hits	30	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q66JZ4	Gene names	D9Ertd402e
Domain Architecture	No domain graphic available
Description	Protein C3orf23 homolog.

DMD_MOUSE
θ value	6.88961 (rank : 27)	NC score	0.004571 (rank : 39)
Query Neighborhood Hits	30	Target Neighborhood Hits	1111	Shared Neighborhood Hits	3
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

OSBL5_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.009369 (rank : 37)
Query Neighborhood Hits	30	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

PRD10_HUMAN
θ value	6.88961 (rank : 29)	NC score	-0.000127 (rank : 40)
Query Neighborhood Hits	30	Target Neighborhood Hits	769	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NQV6, Q9ULI9	Gene names	PRDM10, KIAA1231, PFM7
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 10 (PR domain-containing protein 10).

RASL1_HUMAN
θ value	8.99809 (rank : 30)	NC score	0.011845 (rank : 36)
Query Neighborhood Hits	30	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

DNL3_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.068705 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

DNL3_MOUSE
θ value	θ > 10 (rank : 32)	NC score	0.067042 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

LHR2A_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.050013 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	16	Shared Neighborhood Hits	1
SwissProt Accessions	O00534, Q6UN19, Q6UN20, Q9BVF8	Gene names	LOH11CR2A, BCSC1
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein (Breast cancer suppressor candidate 1) (BCSC-1).

LHR2A_MOUSE
θ value	θ > 10 (rank : 34)	NC score	0.053228 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	16	Shared Neighborhood Hits	1
SwissProt Accessions	Q99KC8, Q3TTU2, Q6UN22, Q8BHA8, Q9CTV9	Gene names	Loh11cr2a
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog.

PAR10_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.072747 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	142	Shared Neighborhood Hits	7
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

PAR12_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.085323 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0J9, Q9H610, Q9NP36, Q9NTI3	Gene names	PARP12, ZC3HDC1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

PAR12_MOUSE
θ value	θ > 10 (rank : 37)	NC score	0.086771 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	60	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BZ20, Q80VL6, Q8K333, Q8R3U2	Gene names	Parp12, Zc3hdc1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

PARP9_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.071430 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	60	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IXQ6, Q8TCP3, Q9BZL8, Q9BZL9	Gene names	PARP9, BAL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein).

PARP9_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.063486 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CAS9, Q99LF9	Gene names	Parp9, Bal
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein homolog).

PARPT_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.123813 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).

Hits sorted by NC score

PARP3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

PARP2_HUMAN
NC score	0.926769 (rank : 2)	θ value	3.70236e-70 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	33	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

PARP2_MOUSE
NC score	0.923806 (rank : 3)	θ value	1.60597e-73 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

PARP1_HUMAN
NC score	0.887538 (rank : 4)	θ value	6.32992e-62 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

PARP1_MOUSE
NC score	0.876410 (rank : 5)	θ value	4.53632e-60 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

PARP4_HUMAN
NC score	0.538458 (rank : 6)	θ value	1.09485e-13 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	93	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

PARPT_MOUSE
NC score	0.153664 (rank : 7)	θ value	0.00869519 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

PAR15_HUMAN
NC score	0.146782 (rank : 8)	θ value	0.00390308 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q460N3, Q8N1K3	Gene names	PARP15, BAL3
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 15 (EC 2.4.2.30) (PARP-15) (B-aggressive lymphoma protein 3).

PARP6_HUMAN
NC score	0.144574 (rank : 9)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q2NL67, Q9H7C5, Q9H9X6, Q9HAF3, Q9NPS6, Q9UFG4	Gene names	PARP6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PARP6_MOUSE
NC score	0.144517 (rank : 10)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P6P7, Q8BVW1	Gene names	Parp6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PAR14_MOUSE
NC score	0.140620 (rank : 11)	θ value	0.0113563 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

PARP8_HUMAN
NC score	0.138226 (rank : 12)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N3A8, Q3KRB7, Q6DHZ1, Q9H754	Gene names	PARP8
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).

PARP8_MOUSE
NC score	0.137905 (rank : 13)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UD82, Q3UDE4, Q3UDU5, Q8VCB5, Q9CYY3	Gene names	Parp8, D13Ertd275e
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).

ZCC2_HUMAN
NC score	0.137334 (rank : 14)	θ value	0.00665767 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

PAR14_HUMAN
NC score	0.133939 (rank : 15)	θ value	0.00665767 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q460N5, Q460N4, Q8J027, Q9H9X9, Q9NV60, Q9ULF2	Gene names	PARP14, BAL2, KIAA1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (B aggressive lymphoma protein 2).

PARPT_HUMAN
NC score	0.123813 (rank : 16)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	30	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).

PAR12_MOUSE
NC score	0.086771 (rank : 17)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	30	Target Neighborhood Hits	60	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BZ20, Q80VL6, Q8K333, Q8R3U2	Gene names	Parp12, Zc3hdc1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

PAR12_HUMAN
NC score	0.085323 (rank : 18)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	30	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0J9, Q9H610, Q9NP36, Q9NTI3	Gene names	PARP12, ZC3HDC1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

TNKS1_HUMAN
NC score	0.081138 (rank : 19)	θ value	0.00665767 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	477	Shared Neighborhood Hits	13
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

TNKS2_HUMAN
NC score	0.078865 (rank : 20)	θ value	0.0193708 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	361	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

PAR10_HUMAN
NC score	0.072747 (rank : 21)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	30	Target Neighborhood Hits	142	Shared Neighborhood Hits	7
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

PARP9_HUMAN
NC score	0.071430 (rank : 22)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	30	Target Neighborhood Hits	60	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IXQ6, Q8TCP3, Q9BZL8, Q9BZL9	Gene names	PARP9, BAL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein).

DNL3_HUMAN
NC score	0.068705 (rank : 23)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	30	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

DNL3_MOUSE
NC score	0.067042 (rank : 24)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	30	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

PARP9_MOUSE
NC score	0.063486 (rank : 25)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	30	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CAS9, Q99LF9	Gene names	Parp9, Bal
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein homolog).

BPHL_HUMAN
NC score	0.062228 (rank : 26)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q86WA6, Q00306, Q13855	Gene names	BPHL
Domain Architecture
Description	Valacyclovir hydrolase precursor (EC 3.1.-.-) (VACVase) (Biphenyl hydrolase-like protein) (Biphenyl hydrolase-related protein) (Bph-rp) (Breast epithelial mucin-associated antigen) (MCNAA).

LHR2A_MOUSE
NC score	0.053228 (rank : 27)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	30	Target Neighborhood Hits	16	Shared Neighborhood Hits	1
SwissProt Accessions	Q99KC8, Q3TTU2, Q6UN22, Q8BHA8, Q9CTV9	Gene names	Loh11cr2a
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog.

LHR2A_HUMAN
NC score	0.050013 (rank : 28)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	30	Target Neighborhood Hits	16	Shared Neighborhood Hits	1
SwissProt Accessions	O00534, Q6UN19, Q6UN20, Q9BVF8	Gene names	LOH11CR2A, BCSC1
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein (Breast cancer suppressor candidate 1) (BCSC-1).

HDAC8_MOUSE
NC score	0.023768 (rank : 29)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VH37, Q3V270, Q9D0K6	Gene names	Hdac8
Domain Architecture
Description	Histone deacetylase 8 (HD8).

XYLT2_HUMAN
NC score	0.020580 (rank : 30)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1B5, Q6UY41, Q86V00	Gene names	XYLT2, XT2
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 2 (EC 2.4.2.26) (Xylosyltransferase II) (xylT-II) (XT-II) (Peptide O-xylosyltransferase 1).

XYLT2_MOUSE
NC score	0.020423 (rank : 31)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPL0, Q5SUY1, Q8K060	Gene names	Xylt2
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 2 (EC 2.4.2.26) (Xylosyltransferase II) (Peptide O- xylosyltransferase 2).

CC023_MOUSE
NC score	0.016912 (rank : 32)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q66JZ4	Gene names	D9Ertd402e
Domain Architecture	No domain graphic available
Description	Protein C3orf23 homolog.

RASL1_MOUSE
NC score	0.014855 (rank : 33)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	148	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

KERA_HUMAN
NC score	0.014515 (rank : 34)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	275	Shared Neighborhood Hits	3
SwissProt Accessions	O60938	Gene names	KERA
Domain Architecture
Description	Keratocan precursor (KTN) (Keratan sulfate proteoglycan keratocan).

KERA_MOUSE
NC score	0.013020 (rank : 35)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	264	Shared Neighborhood Hits	3
SwissProt Accessions	O35367	Gene names	Kera, Ktcn
Domain Architecture
Description	Keratocan precursor (KTN) (Keratan sulfate proteoglycan keratocan).

RASL1_HUMAN
NC score	0.011845 (rank : 36)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

OSBL5_HUMAN
NC score	0.009369 (rank : 37)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

MACF1_MOUSE
NC score	0.006323 (rank : 38)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	1313	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

DMD_MOUSE
NC score	0.004571 (rank : 39)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	1111	Shared Neighborhood Hits	3
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

PRD10_HUMAN
NC score	-0.000127 (rank : 40)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	769	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NQV6, Q9ULI9	Gene names	PRDM10, KIAA1231, PFM7
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 10 (PR domain-containing protein 10).