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Network neighborhood for query Sequence : PARPT_HUMAN

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PARPT_HUMAN
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PARPT_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).

PARPT_MOUSE
θ value	0 (rank : 2)	NC score	0.994878 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

PAR12_HUMAN
θ value	1.01294e-51 (rank : 3)	NC score	0.855252 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H0J9, Q9H610, Q9NP36, Q9NTI3	Gene names	PARP12, ZC3HDC1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

PAR12_MOUSE
θ value	5.55816e-50 (rank : 4)	NC score	0.851758 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	60	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BZ20, Q80VL6, Q8K333, Q8R3U2	Gene names	Parp12, Zc3hdc1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

PAR15_HUMAN
θ value	4.72714e-33 (rank : 5)	NC score	0.789227 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q460N3, Q8N1K3	Gene names	PARP15, BAL3
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 15 (EC 2.4.2.30) (PARP-15) (B-aggressive lymphoma protein 3).

ZCC2_HUMAN
θ value	2.59387e-31 (rank : 6)	NC score	0.795209 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

PAR14_HUMAN
θ value	2.19584e-30 (rank : 7)	NC score	0.707481 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	Q460N5, Q460N4, Q8J027, Q9H9X9, Q9NV60, Q9ULF2	Gene names	PARP14, BAL2, KIAA1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (B aggressive lymphoma protein 2).

PAR14_MOUSE
θ value	6.38894e-30 (rank : 8)	NC score	0.699559 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

PAR10_HUMAN
θ value	1.80048e-24 (rank : 9)	NC score	0.698763 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

PARP9_MOUSE
θ value	4.59992e-12 (rank : 10)	NC score	0.556105 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CAS9, Q99LF9	Gene names	Parp9, Bal
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein homolog).

PARP9_HUMAN
θ value	7.84624e-12 (rank : 11)	NC score	0.575375 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IXQ6, Q8TCP3, Q9BZL8, Q9BZL9	Gene names	PARP9, BAL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein).

TNKS2_HUMAN
θ value	6.87365e-08 (rank : 12)	NC score	0.146171 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	361	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

TNKS1_HUMAN
θ value	1.87187e-05 (rank : 13)	NC score	0.123208 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	477	Shared Neighborhood Hits	18
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

DHX57_HUMAN
θ value	0.163984 (rank : 14)	NC score	0.047256 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	109	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

ZC3H3_HUMAN
θ value	0.163984 (rank : 15)	NC score	0.106234 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	159	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZC3H3_MOUSE
θ value	0.163984 (rank : 16)	NC score	0.102876 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	188	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

PARP2_MOUSE
θ value	0.365318 (rank : 17)	NC score	0.073872 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	53	Shared Neighborhood Hits	8
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

ZC3H6_MOUSE
θ value	0.62314 (rank : 18)	NC score	0.072949 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	239	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ZC3H6_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.073975 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

PARP1_HUMAN
θ value	1.38821 (rank : 20)	NC score	0.067636 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

TAOK3_MOUSE
θ value	1.38821 (rank : 21)	NC score	0.000564 (rank : 44)
Query Neighborhood Hits	36	Target Neighborhood Hits	1458	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

CN155_HUMAN
θ value	1.81305 (rank : 22)	NC score	0.020228 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	385	Shared Neighborhood Hits	3
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

LARP1_HUMAN
θ value	1.81305 (rank : 23)	NC score	0.042436 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

PARP2_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.064402 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

ANR38_MOUSE
θ value	3.0926 (rank : 25)	NC score	0.022463 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	512	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CF061_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.040849 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXL9, Q9HCV5	Gene names	C6orf61
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf61.

PAR6B_HUMAN
θ value	3.0926 (rank : 27)	NC score	0.012605 (rank : 38)
Query Neighborhood Hits	36	Target Neighborhood Hits	126	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

HEMGN_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.020662 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXL5, Q6XAR3, Q86XY5, Q9NPC0	Gene names	HEMGN, EDAG, NDR
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (Erythroid differentiation-associated gene protein) (EDAG-1).

PARP1_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.056935 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

CCDC8_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.018840 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H0W5, Q8TB26	Gene names	CCDC8
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 8.

GSCR1_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.010445 (rank : 39)
Query Neighborhood Hits	36	Target Neighborhood Hits	674	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

NOTC1_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.006707 (rank : 41)
Query Neighborhood Hits	36	Target Neighborhood Hits	906	Shared Neighborhood Hits	5
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CLMN_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.004512 (rank : 42)
Query Neighborhood Hits	36	Target Neighborhood Hits	180	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

SRGP1_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.003604 (rank : 43)
Query Neighborhood Hits	36	Target Neighborhood Hits	390	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

SRRM2_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.006948 (rank : 40)
Query Neighborhood Hits	36	Target Neighborhood Hits	1296	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ZC3H8_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.041033 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N5P1, Q9BZ75	Gene names	ZC3H8, ZC3HDC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8.

CPSF4_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.051947 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	O95639, Q86TF8, Q9BTW6	Gene names	CPSF4, CPSF30, NAR, NEB1
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog).

H2AW_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.061025 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P0M6, Q5SQT2	Gene names	H2AFY2, MACROH2A2
Domain Architecture
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AW_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.059865 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CCK0, Q3TNT4, Q925I6	Gene names	H2afy2, H2afy3
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AY_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.077598 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	O75367, O75377, Q503A8, Q7Z5E3, Q96D41, Q9H8P3, Q9UP96	Gene names	H2AFY, MACROH2A1
Domain Architecture
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205).

H2AY_MOUSE
θ value	θ > 10 (rank : 41)	NC score	0.077232 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZQ8, Q91VZ2, Q9QZQ7	Gene names	H2afy
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y).

LRP16_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.173586 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BQ69, Q9UH96	Gene names	LRP16
Domain Architecture
Description	Protein LRP16.

LRP16_MOUSE
θ value	θ > 10 (rank : 43)	NC score	0.166872 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q922B1	Gene names	Lrp16
Domain Architecture
Description	Protein LRP16.

PARP3_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.123813 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

Hits sorted by NC score

PARPT_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).

PARPT_MOUSE
NC score	0.994878 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

PAR12_HUMAN
NC score	0.855252 (rank : 3)	θ value	1.01294e-51 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H0J9, Q9H610, Q9NP36, Q9NTI3	Gene names	PARP12, ZC3HDC1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

PAR12_MOUSE
NC score	0.851758 (rank : 4)	θ value	5.55816e-50 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	60	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BZ20, Q80VL6, Q8K333, Q8R3U2	Gene names	Parp12, Zc3hdc1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

ZCC2_HUMAN
NC score	0.795209 (rank : 5)	θ value	2.59387e-31 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

PAR15_HUMAN
NC score	0.789227 (rank : 6)	θ value	4.72714e-33 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q460N3, Q8N1K3	Gene names	PARP15, BAL3
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 15 (EC 2.4.2.30) (PARP-15) (B-aggressive lymphoma protein 3).

PAR14_HUMAN
NC score	0.707481 (rank : 7)	θ value	2.19584e-30 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	Q460N5, Q460N4, Q8J027, Q9H9X9, Q9NV60, Q9ULF2	Gene names	PARP14, BAL2, KIAA1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (B aggressive lymphoma protein 2).

PAR14_MOUSE
NC score	0.699559 (rank : 8)	θ value	6.38894e-30 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

PAR10_HUMAN
NC score	0.698763 (rank : 9)	θ value	1.80048e-24 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

PARP9_HUMAN
NC score	0.575375 (rank : 10)	θ value	7.84624e-12 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IXQ6, Q8TCP3, Q9BZL8, Q9BZL9	Gene names	PARP9, BAL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein).

PARP9_MOUSE
NC score	0.556105 (rank : 11)	θ value	4.59992e-12 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CAS9, Q99LF9	Gene names	Parp9, Bal
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein homolog).

LRP16_HUMAN
NC score	0.173586 (rank : 12)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	36	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BQ69, Q9UH96	Gene names	LRP16
Domain Architecture
Description	Protein LRP16.

LRP16_MOUSE
NC score	0.166872 (rank : 13)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	36	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q922B1	Gene names	Lrp16
Domain Architecture
Description	Protein LRP16.

TNKS2_HUMAN
NC score	0.146171 (rank : 14)	θ value	6.87365e-08 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	361	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

PARP3_HUMAN
NC score	0.123813 (rank : 15)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	36	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

TNKS1_HUMAN
NC score	0.123208 (rank : 16)	θ value	1.87187e-05 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	477	Shared Neighborhood Hits	18
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ZC3H3_HUMAN
NC score	0.106234 (rank : 17)	θ value	0.163984 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	159	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZC3H3_MOUSE
NC score	0.102876 (rank : 18)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	188	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

H2AY_HUMAN
NC score	0.077598 (rank : 19)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	36	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	O75367, O75377, Q503A8, Q7Z5E3, Q96D41, Q9H8P3, Q9UP96	Gene names	H2AFY, MACROH2A1
Domain Architecture
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205).

H2AY_MOUSE
NC score	0.077232 (rank : 20)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	36	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZQ8, Q91VZ2, Q9QZQ7	Gene names	H2afy
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y).

ZC3H6_HUMAN
NC score	0.073975 (rank : 21)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

PARP2_MOUSE
NC score	0.073872 (rank : 22)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	53	Shared Neighborhood Hits	8
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

ZC3H6_MOUSE
NC score	0.072949 (rank : 23)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	239	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

PARP1_HUMAN
NC score	0.067636 (rank : 24)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

PARP2_HUMAN
NC score	0.064402 (rank : 25)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

H2AW_HUMAN
NC score	0.061025 (rank : 26)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	36	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P0M6, Q5SQT2	Gene names	H2AFY2, MACROH2A2
Domain Architecture
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AW_MOUSE
NC score	0.059865 (rank : 27)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	36	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CCK0, Q3TNT4, Q925I6	Gene names	H2afy2, H2afy3
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

PARP1_MOUSE
NC score	0.056935 (rank : 28)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

CPSF4_HUMAN
NC score	0.051947 (rank : 29)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	O95639, Q86TF8, Q9BTW6	Gene names	CPSF4, CPSF30, NAR, NEB1
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog).

DHX57_HUMAN
NC score	0.047256 (rank : 30)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	109	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

LARP1_HUMAN
NC score	0.042436 (rank : 31)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

ZC3H8_HUMAN
NC score	0.041033 (rank : 32)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N5P1, Q9BZ75	Gene names	ZC3H8, ZC3HDC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8.

CF061_HUMAN
NC score	0.040849 (rank : 33)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXL9, Q9HCV5	Gene names	C6orf61
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf61.

ANR38_MOUSE
NC score	0.022463 (rank : 34)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	512	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

HEMGN_HUMAN
NC score	0.020662 (rank : 35)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXL5, Q6XAR3, Q86XY5, Q9NPC0	Gene names	HEMGN, EDAG, NDR
Domain Architecture	No domain graphic available
Description	Hemogen (Hemopoietic gene protein) (Negative differentiation regulator protein) (Erythroid differentiation-associated gene protein) (EDAG-1).

CN155_HUMAN
NC score	0.020228 (rank : 36)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	385	Shared Neighborhood Hits	3
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CCDC8_HUMAN
NC score	0.018840 (rank : 37)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H0W5, Q8TB26	Gene names	CCDC8
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 8.

PAR6B_HUMAN
NC score	0.012605 (rank : 38)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	126	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYG5, Q9Y510	Gene names	PARD6B, PAR6B
Domain Architecture
Description	Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B).

GSCR1_HUMAN
NC score	0.010445 (rank : 39)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	674	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SRRM2_HUMAN
NC score	0.006948 (rank : 40)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	1296	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

NOTC1_HUMAN
NC score	0.006707 (rank : 41)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	906	Shared Neighborhood Hits	5
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CLMN_MOUSE
NC score	0.004512 (rank : 42)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	180	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C5W0, Q91V71, Q91XT7, Q91XT8, Q91XU9	Gene names	Clmn
Domain Architecture
Description	Calmin.

SRGP1_HUMAN
NC score	0.003604 (rank : 43)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	390	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

TAOK3_MOUSE
NC score	0.000564 (rank : 44)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	1458	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).