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Network neighborhood for query Sequence : CPSF4_HUMAN

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CPSF4_HUMAN
SwissProt Accessions	O95639, Q86TF8, Q9BTW6	Gene names	CPSF4, CPSF30, NAR, NEB1
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CPSF4_HUMAN
θ value	1.51632e-156 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	68
SwissProt Accessions	O95639, Q86TF8, Q9BTW6	Gene names	CPSF4, CPSF30, NAR, NEB1
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog).

CPSF4_MOUSE
θ value	7.87842e-113 (rank : 2)	NC score	0.986402 (rank : 2)
Query Neighborhood Hits	68	Target Neighborhood Hits	58	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BQZ5, O54930	Gene names	Cpsf4, Cpsf30
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K).

ZC3H3_MOUSE
θ value	2.06002e-20 (rank : 3)	NC score	0.641687 (rank : 3)
Query Neighborhood Hits	68	Target Neighborhood Hits	188	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZC3H3_HUMAN
θ value	1.47631e-18 (rank : 4)	NC score	0.638360 (rank : 4)
Query Neighborhood Hits	68	Target Neighborhood Hits	159	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZC3H6_MOUSE
θ value	6.21693e-09 (rank : 5)	NC score	0.515968 (rank : 7)
Query Neighborhood Hits	68	Target Neighborhood Hits	239	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ZC3H6_HUMAN
θ value	5.26297e-08 (rank : 6)	NC score	0.509475 (rank : 8)
Query Neighborhood Hits	68	Target Neighborhood Hits	228	Shared Neighborhood Hits	39
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ZC3H8_MOUSE
θ value	6.87365e-08 (rank : 7)	NC score	0.569499 (rank : 6)
Query Neighborhood Hits	68	Target Neighborhood Hits	56	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JJ48, Q80X92	Gene names	Zc3h8, Fliz1, Zc3hdc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8 (Fetal liver zinc finger protein 1).

CS007_HUMAN
θ value	8.97725e-08 (rank : 8)	NC score	0.484192 (rank : 9)
Query Neighborhood Hits	68	Target Neighborhood Hits	401	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CS007_MOUSE
θ value	8.97725e-08 (rank : 9)	NC score	0.473821 (rank : 10)
Query Neighborhood Hits	68	Target Neighborhood Hits	464	Shared Neighborhood Hits	40
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

ZC3H8_HUMAN
θ value	1.17247e-07 (rank : 10)	NC score	0.572046 (rank : 5)
Query Neighborhood Hits	68	Target Neighborhood Hits	57	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N5P1, Q9BZ75	Gene names	ZC3H8, ZC3HDC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8.

ZC3H5_HUMAN
θ value	2.44474e-05 (rank : 11)	NC score	0.285139 (rank : 24)
Query Neighborhood Hits	68	Target Neighborhood Hits	134	Shared Neighborhood Hits	23
SwissProt Accessions	Q9C0B0	Gene names	ZC3H5, KIAA1753, ZC3HDC5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

ZC11A_HUMAN
θ value	5.44631e-05 (rank : 12)	NC score	0.304560 (rank : 16)
Query Neighborhood Hits	68	Target Neighborhood Hits	170	Shared Neighborhood Hits	20
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

MKRN2_MOUSE
θ value	9.29e-05 (rank : 13)	NC score	0.411502 (rank : 11)
Query Neighborhood Hits	68	Target Neighborhood Hits	130	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

ZC11A_MOUSE
θ value	9.29e-05 (rank : 14)	NC score	0.293851 (rank : 20)
Query Neighborhood Hits	68	Target Neighborhood Hits	216	Shared Neighborhood Hits	20
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

ZC3H5_MOUSE
θ value	9.29e-05 (rank : 15)	NC score	0.286738 (rank : 23)
Query Neighborhood Hits	68	Target Neighborhood Hits	136	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BL48, Q8BVI6, Q99JZ8, Q99LL9	Gene names	Zc3h5, Kiaa1753, Zc3hdc5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

MKRN2_HUMAN
θ value	0.000121331 (rank : 16)	NC score	0.407979 (rank : 12)
Query Neighborhood Hits	68	Target Neighborhood Hits	129	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN1_HUMAN
θ value	0.000270298 (rank : 17)	NC score	0.378982 (rank : 14)
Query Neighborhood Hits	68	Target Neighborhood Hits	141	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MKRN1_MOUSE
θ value	0.000461057 (rank : 18)	NC score	0.380564 (rank : 13)
Query Neighborhood Hits	68	Target Neighborhood Hits	141	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

MKRN4_HUMAN
θ value	0.00665767 (rank : 19)	NC score	0.326555 (rank : 15)
Query Neighborhood Hits	68	Target Neighborhood Hits	147	Shared Neighborhood Hits	32
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

RECQ4_MOUSE
θ value	0.0148317 (rank : 20)	NC score	0.072259 (rank : 45)
Query Neighborhood Hits	68	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

PAR12_MOUSE
θ value	0.0330416 (rank : 21)	NC score	0.128763 (rank : 35)
Query Neighborhood Hits	68	Target Neighborhood Hits	60	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BZ20, Q80VL6, Q8K333, Q8R3U2	Gene names	Parp12, Zc3hdc1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

TISB_HUMAN
θ value	0.0431538 (rank : 22)	NC score	0.297212 (rank : 17)
Query Neighborhood Hits	68	Target Neighborhood Hits	56	Shared Neighborhood Hits	32
SwissProt Accessions	Q07352, Q13851	Gene names	ZFP36L1, BERG36, BRF1, ERF1, TIS11B
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein) (EGF-response factor 1) (ERF-1).

TISB_MOUSE
θ value	0.0431538 (rank : 23)	NC score	0.296009 (rank : 18)
Query Neighborhood Hits	68	Target Neighborhood Hits	56	Shared Neighborhood Hits	33
SwissProt Accessions	P23950	Gene names	Zfp36l1, Brf1, Tis11b
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein).

MBN3_MOUSE
θ value	0.0563607 (rank : 24)	NC score	0.227484 (rank : 29)
Query Neighborhood Hits	68	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R003	Gene names	Mbnl3, Chcr, Mbxl
Domain Architecture	No domain graphic available
Description	Muscleblind-like X-linked protein (Muscleblind-like protein 3) (Cys3His CCG1-required protein) (Protein MCHCR).

TISD_HUMAN
θ value	0.0563607 (rank : 25)	NC score	0.284695 (rank : 25)
Query Neighborhood Hits	68	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	P47974, Q9BSJ3	Gene names	ZFP36L2, BRF2, ERF2, TIS11D
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein) (EGF-response factor 2) (ERF-2).

TISD_MOUSE
θ value	0.0563607 (rank : 26)	NC score	0.295592 (rank : 19)
Query Neighborhood Hits	68	Target Neighborhood Hits	62	Shared Neighborhood Hits	31
SwissProt Accessions	P23949	Gene names	Zfp36l2, Brf2, Tis11d
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein).

MBNL_HUMAN
θ value	0.0736092 (rank : 27)	NC score	0.204676 (rank : 31)
Query Neighborhood Hits	68	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NR56, O43311, O43797	Gene names	MBNL1, EXP, KIAA0428, MBNL
Domain Architecture
Description	Muscleblind-like protein (Triplet-expansion RNA-binding protein).

MBNL_MOUSE
θ value	0.0736092 (rank : 28)	NC score	0.205948 (rank : 30)
Query Neighborhood Hits	68	Target Neighborhood Hits	33	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JKP5	Gene names	Mbnl1, Exp, Mbnl
Domain Architecture	No domain graphic available
Description	Muscleblind-like protein (Triplet-expansion RNA-binding protein).

Z3H7A_HUMAN
θ value	0.125558 (rank : 29)	NC score	0.086236 (rank : 41)
Query Neighborhood Hits	68	Target Neighborhood Hits	105	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

MKRN3_MOUSE
θ value	0.163984 (rank : 30)	NC score	0.268602 (rank : 26)
Query Neighborhood Hits	68	Target Neighborhood Hits	137	Shared Neighborhood Hits	35
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

MKRN3_HUMAN
θ value	0.21417 (rank : 31)	NC score	0.262728 (rank : 27)
Query Neighborhood Hits	68	Target Neighborhood Hits	165	Shared Neighborhood Hits	30
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

PAR12_HUMAN
θ value	0.21417 (rank : 32)	NC score	0.131724 (rank : 32)
Query Neighborhood Hits	68	Target Neighborhood Hits	42	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H0J9, Q9H610, Q9NP36, Q9NTI3	Gene names	PARP12, ZC3HDC1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

MBN3_HUMAN
θ value	0.279714 (rank : 33)	NC score	0.230331 (rank : 28)
Query Neighborhood Hits	68	Target Neighborhood Hits	61	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NUK0, Q5JXN8, Q5JXN9, Q5JXP4, Q6UDQ1, Q8TAD9, Q8TAF4, Q9H0Z7, Q9UF37	Gene names	MBNL3, CHCR, MBLX39, MBXL
Domain Architecture
Description	Muscleblind-like X-linked protein (Muscleblind-like protein 3) (Cys3His CCG1-required protein) (Protein HCHCR).

R113B_HUMAN
θ value	0.47712 (rank : 34)	NC score	0.115485 (rank : 36)
Query Neighborhood Hits	68	Target Neighborhood Hits	165	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RBM22_HUMAN
θ value	0.47712 (rank : 35)	NC score	0.131095 (rank : 33)
Query Neighborhood Hits	68	Target Neighborhood Hits	189	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NW64, O95607	Gene names	RBM22
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22).

RBM22_MOUSE
θ value	0.47712 (rank : 36)	NC score	0.131095 (rank : 34)
Query Neighborhood Hits	68	Target Neighborhood Hits	189	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BHS3, Q3TJB0, Q9CXA0	Gene names	Rbm22
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22).

TTP_HUMAN
θ value	0.47712 (rank : 37)	NC score	0.289328 (rank : 21)
Query Neighborhood Hits	68	Target Neighborhood Hits	86	Shared Neighborhood Hits	35
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

CNBP_HUMAN
θ value	0.62314 (rank : 38)	NC score	0.101751 (rank : 38)
Query Neighborhood Hits	68	Target Neighborhood Hits	196	Shared Neighborhood Hits	16
SwissProt Accessions	P62633, P20694, Q5QJR0, Q6PJI7, Q96NV3	Gene names	CNBP, ZNF9
Domain Architecture	No domain graphic available
Description	Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9).

CNBP_MOUSE
θ value	0.62314 (rank : 39)	NC score	0.099704 (rank : 39)
Query Neighborhood Hits	68	Target Neighborhood Hits	215	Shared Neighborhood Hits	16
SwissProt Accessions	P53996, Q80Y06, Q8BP23	Gene names	Cnbp, Cnbp1, Znf9
Domain Architecture	No domain graphic available
Description	Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9).

MAVS_HUMAN
θ value	0.813845 (rank : 40)	NC score	0.052182 (rank : 51)
Query Neighborhood Hits	68	Target Neighborhood Hits	271	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

RBBP6_HUMAN
θ value	0.813845 (rank : 41)	NC score	0.045233 (rank : 57)
Query Neighborhood Hits	68	Target Neighborhood Hits	1135	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	0.813845 (rank : 42)	NC score	0.050151 (rank : 54)
Query Neighborhood Hits	68	Target Neighborhood Hits	1014	Shared Neighborhood Hits	13
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TTP_MOUSE
θ value	0.813845 (rank : 43)	NC score	0.288998 (rank : 22)
Query Neighborhood Hits	68	Target Neighborhood Hits	75	Shared Neighborhood Hits	35
SwissProt Accessions	P22893, P11520	Gene names	Zfp36, Tis11, Tis11a
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (TPA-induced sequence 11).

ZCH12_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.034670 (rank : 60)
Query Neighborhood Hits	68	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PEW1, Q6PID5, Q8N1C1	Gene names	ZCCHC12
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 12.

R113A_HUMAN
θ value	1.06291 (rank : 45)	NC score	0.106005 (rank : 37)
Query Neighborhood Hits	68	Target Neighborhood Hits	177	Shared Neighborhood Hits	22
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

DHX57_HUMAN
θ value	1.38821 (rank : 46)	NC score	0.066773 (rank : 46)
Query Neighborhood Hits	68	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DUS3L_MOUSE
θ value	1.38821 (rank : 47)	NC score	0.063947 (rank : 48)
Query Neighborhood Hits	68	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q91XI1, Q3TZQ1, Q7TT12	Gene names	Dus3l
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

SFRS7_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.049183 (rank : 55)
Query Neighborhood Hits	68	Target Neighborhood Hits	191	Shared Neighborhood Hits	14
SwissProt Accessions	Q16629	Gene names	SFRS7
Domain Architecture
Description	Splicing factor, arginine/serine-rich 7 (Splicing factor 9G8).

SFRS7_MOUSE
θ value	1.38821 (rank : 49)	NC score	0.049136 (rank : 56)
Query Neighborhood Hits	68	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BL97, Q8BMC6, Q8BUR2, Q8R2N4, Q8R3E9, Q91YS1	Gene names	Sfrs7
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 7.

ZCH13_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.092974 (rank : 40)
Query Neighborhood Hits	68	Target Neighborhood Hits	151	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WW36	Gene names	ZCCHC13
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 13.

ZCHC3_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.081825 (rank : 42)
Query Neighborhood Hits	68	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NUD5, Q6NT79	Gene names	ZCCHC3, C20orf99
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 3.

DHX57_MOUSE
θ value	3.0926 (rank : 52)	NC score	0.057157 (rank : 49)
Query Neighborhood Hits	68	Target Neighborhood Hits	125	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

ECT2_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.013818 (rank : 67)
Query Neighborhood Hits	68	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

NCOA1_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.015207 (rank : 66)
Query Neighborhood Hits	68	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

TRM1_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.077025 (rank : 44)
Query Neighborhood Hits	68	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NXH9, O76103, Q548Y5, Q8WVA6	Gene names	TRMT1
Domain Architecture
Description	N(2),N(2)-dimethylguanosine tRNA methyltransferase (EC 2.1.1.32) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2- dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase).

ZCH14_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.034735 (rank : 59)
Query Neighborhood Hits	68	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

ZCHC7_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.064902 (rank : 47)
Query Neighborhood Hits	68	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N3Z6, Q5T0Q8, Q5T0Q9, Q5T0R0, Q8N2M1, Q8N4J2, Q8TBK8, Q9H648, Q9P0F0	Gene names	ZCCHC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 7.

DUS3L_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.081472 (rank : 43)
Query Neighborhood Hits	68	Target Neighborhood Hits	44	Shared Neighborhood Hits	20
SwissProt Accessions	Q96G46, Q96HM5, Q9BSU4, Q9H877, Q9NPR1	Gene names	DUS3L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

U2AFL_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.022200 (rank : 61)
Query Neighborhood Hits	68	Target Neighborhood Hits	389	Shared Neighborhood Hits	9
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

ERO1B_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.016484 (rank : 64)
Query Neighborhood Hits	68	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q86YB8, Q8IZ11, Q9NR62	Gene names	ERO1LB
Domain Architecture	No domain graphic available
Description	ERO1-like protein beta precursor (EC 1.8.4.-) (ERO1-Lbeta) (Oxidoreductin-1-Lbeta) (Endoplasmic oxidoreductin-1-like protein B).

ERO1B_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.016440 (rank : 65)
Query Neighborhood Hits	68	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R2E9	Gene names	Ero1lb
Domain Architecture	No domain graphic available
Description	ERO1-like protein beta precursor (EC 1.8.4.-) (ERO1-Lbeta) (Oxidoreductin-1-Lbeta) (Endoplasmic oxidoreductin-1-like protein B).

GRN_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.008156 (rank : 68)
Query Neighborhood Hits	68	Target Neighborhood Hits	268	Shared Neighborhood Hits	3
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

NELL1_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.001832 (rank : 69)
Query Neighborhood Hits	68	Target Neighborhood Hits	451	Shared Neighborhood Hits	3
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

RBM4_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.021737 (rank : 62)
Query Neighborhood Hits	68	Target Neighborhood Hits	219	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BWF3, O02916, Q6P1P2, Q8WU85	Gene names	RBM4, RBM4A
Domain Architecture	No domain graphic available
Description	RNA-binding protein 4 (RNA-binding motif protein 4) (RNA-binding motif protein 4a) (Lark homolog) (hLark).

RBM4_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.021299 (rank : 63)
Query Neighborhood Hits	68	Target Neighborhood Hits	223	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C7Q4, O08752, Q8BN66	Gene names	Rbm4, Rbm4a
Domain Architecture	No domain graphic available
Description	RNA-binding protein 4 (RNA-binding motif protein 4) (RNA-binding motif protein 4a) (Lark homolog) (mLark).

TRM1_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.052243 (rank : 50)
Query Neighborhood Hits	68	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	Q3TX08, Q3TBY4	Gene names	Trmt1, D8Ertd812e
Domain Architecture	No domain graphic available
Description	N(2),N(2)-dimethylguanosine tRNA methyltransferase (EC 2.1.1.32) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2- dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase).

ZCH14_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.036209 (rank : 58)
Query Neighborhood Hits	68	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

ZN615_HUMAN
θ value	8.99809 (rank : 68)	NC score	-0.003211 (rank : 70)
Query Neighborhood Hits	68	Target Neighborhood Hits	775	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N8J6	Gene names	ZNF615
Domain Architecture	No domain graphic available
Description	Zinc finger protein 615.

PARPT_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.051947 (rank : 53)
Query Neighborhood Hits	68	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).

PARPT_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.052068 (rank : 52)
Query Neighborhood Hits	68	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

Hits sorted by NC score

CPSF4_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.51632e-156 (rank : 1)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	68
SwissProt Accessions	O95639, Q86TF8, Q9BTW6	Gene names	CPSF4, CPSF30, NAR, NEB1
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog).

CPSF4_MOUSE
NC score	0.986402 (rank : 2)	θ value	7.87842e-113 (rank : 2)
Query Neighborhood Hits	68	Target Neighborhood Hits	58	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BQZ5, O54930	Gene names	Cpsf4, Cpsf30
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K).

ZC3H3_MOUSE
NC score	0.641687 (rank : 3)	θ value	2.06002e-20 (rank : 3)
Query Neighborhood Hits	68	Target Neighborhood Hits	188	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZC3H3_HUMAN
NC score	0.638360 (rank : 4)	θ value	1.47631e-18 (rank : 4)
Query Neighborhood Hits	68	Target Neighborhood Hits	159	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZC3H8_HUMAN
NC score	0.572046 (rank : 5)	θ value	1.17247e-07 (rank : 10)
Query Neighborhood Hits	68	Target Neighborhood Hits	57	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N5P1, Q9BZ75	Gene names	ZC3H8, ZC3HDC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8.

ZC3H8_MOUSE
NC score	0.569499 (rank : 6)	θ value	6.87365e-08 (rank : 7)
Query Neighborhood Hits	68	Target Neighborhood Hits	56	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JJ48, Q80X92	Gene names	Zc3h8, Fliz1, Zc3hdc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8 (Fetal liver zinc finger protein 1).

ZC3H6_MOUSE
NC score	0.515968 (rank : 7)	θ value	6.21693e-09 (rank : 5)
Query Neighborhood Hits	68	Target Neighborhood Hits	239	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ZC3H6_HUMAN
NC score	0.509475 (rank : 8)	θ value	5.26297e-08 (rank : 6)
Query Neighborhood Hits	68	Target Neighborhood Hits	228	Shared Neighborhood Hits	39
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

CS007_HUMAN
NC score	0.484192 (rank : 9)	θ value	8.97725e-08 (rank : 8)
Query Neighborhood Hits	68	Target Neighborhood Hits	401	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CS007_MOUSE
NC score	0.473821 (rank : 10)	θ value	8.97725e-08 (rank : 9)
Query Neighborhood Hits	68	Target Neighborhood Hits	464	Shared Neighborhood Hits	40
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

MKRN2_MOUSE
NC score	0.411502 (rank : 11)	θ value	9.29e-05 (rank : 13)
Query Neighborhood Hits	68	Target Neighborhood Hits	130	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

MKRN2_HUMAN
NC score	0.407979 (rank : 12)	θ value	0.000121331 (rank : 16)
Query Neighborhood Hits	68	Target Neighborhood Hits	129	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN1_MOUSE
NC score	0.380564 (rank : 13)	θ value	0.000461057 (rank : 18)
Query Neighborhood Hits	68	Target Neighborhood Hits	141	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

MKRN1_HUMAN
NC score	0.378982 (rank : 14)	θ value	0.000270298 (rank : 17)
Query Neighborhood Hits	68	Target Neighborhood Hits	141	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MKRN4_HUMAN
NC score	0.326555 (rank : 15)	θ value	0.00665767 (rank : 19)
Query Neighborhood Hits	68	Target Neighborhood Hits	147	Shared Neighborhood Hits	32
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

ZC11A_HUMAN
NC score	0.304560 (rank : 16)	θ value	5.44631e-05 (rank : 12)
Query Neighborhood Hits	68	Target Neighborhood Hits	170	Shared Neighborhood Hits	20
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

TISB_HUMAN
NC score	0.297212 (rank : 17)	θ value	0.0431538 (rank : 22)
Query Neighborhood Hits	68	Target Neighborhood Hits	56	Shared Neighborhood Hits	32
SwissProt Accessions	Q07352, Q13851	Gene names	ZFP36L1, BERG36, BRF1, ERF1, TIS11B
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein) (EGF-response factor 1) (ERF-1).

TISB_MOUSE
NC score	0.296009 (rank : 18)	θ value	0.0431538 (rank : 23)
Query Neighborhood Hits	68	Target Neighborhood Hits	56	Shared Neighborhood Hits	33
SwissProt Accessions	P23950	Gene names	Zfp36l1, Brf1, Tis11b
Domain Architecture
Description	Butyrate response factor 1 (TIS11B protein).

TISD_MOUSE
NC score	0.295592 (rank : 19)	θ value	0.0563607 (rank : 26)
Query Neighborhood Hits	68	Target Neighborhood Hits	62	Shared Neighborhood Hits	31
SwissProt Accessions	P23949	Gene names	Zfp36l2, Brf2, Tis11d
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein).

ZC11A_MOUSE
NC score	0.293851 (rank : 20)	θ value	9.29e-05 (rank : 14)
Query Neighborhood Hits	68	Target Neighborhood Hits	216	Shared Neighborhood Hits	20
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

TTP_HUMAN
NC score	0.289328 (rank : 21)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	68	Target Neighborhood Hits	86	Shared Neighborhood Hits	35
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

TTP_MOUSE
NC score	0.288998 (rank : 22)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	68	Target Neighborhood Hits	75	Shared Neighborhood Hits	35
SwissProt Accessions	P22893, P11520	Gene names	Zfp36, Tis11, Tis11a
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (TPA-induced sequence 11).

ZC3H5_MOUSE
NC score	0.286738 (rank : 23)	θ value	9.29e-05 (rank : 15)
Query Neighborhood Hits	68	Target Neighborhood Hits	136	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BL48, Q8BVI6, Q99JZ8, Q99LL9	Gene names	Zc3h5, Kiaa1753, Zc3hdc5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

ZC3H5_HUMAN
NC score	0.285139 (rank : 24)	θ value	2.44474e-05 (rank : 11)
Query Neighborhood Hits	68	Target Neighborhood Hits	134	Shared Neighborhood Hits	23
SwissProt Accessions	Q9C0B0	Gene names	ZC3H5, KIAA1753, ZC3HDC5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

TISD_HUMAN
NC score	0.284695 (rank : 25)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	68	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	P47974, Q9BSJ3	Gene names	ZFP36L2, BRF2, ERF2, TIS11D
Domain Architecture
Description	Butyrate response factor 2 (TIS11D protein) (EGF-response factor 2) (ERF-2).

MKRN3_MOUSE
NC score	0.268602 (rank : 26)	θ value	0.163984 (rank : 30)
Query Neighborhood Hits	68	Target Neighborhood Hits	137	Shared Neighborhood Hits	35
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

MKRN3_HUMAN
NC score	0.262728 (rank : 27)	θ value	0.21417 (rank : 31)
Query Neighborhood Hits	68	Target Neighborhood Hits	165	Shared Neighborhood Hits	30
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

MBN3_HUMAN
NC score	0.230331 (rank : 28)	θ value	0.279714 (rank : 33)
Query Neighborhood Hits	68	Target Neighborhood Hits	61	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NUK0, Q5JXN8, Q5JXN9, Q5JXP4, Q6UDQ1, Q8TAD9, Q8TAF4, Q9H0Z7, Q9UF37	Gene names	MBNL3, CHCR, MBLX39, MBXL
Domain Architecture
Description	Muscleblind-like X-linked protein (Muscleblind-like protein 3) (Cys3His CCG1-required protein) (Protein HCHCR).

MBN3_MOUSE
NC score	0.227484 (rank : 29)	θ value	0.0563607 (rank : 24)
Query Neighborhood Hits	68	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R003	Gene names	Mbnl3, Chcr, Mbxl
Domain Architecture	No domain graphic available
Description	Muscleblind-like X-linked protein (Muscleblind-like protein 3) (Cys3His CCG1-required protein) (Protein MCHCR).

MBNL_MOUSE
NC score	0.205948 (rank : 30)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	68	Target Neighborhood Hits	33	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JKP5	Gene names	Mbnl1, Exp, Mbnl
Domain Architecture	No domain graphic available
Description	Muscleblind-like protein (Triplet-expansion RNA-binding protein).

MBNL_HUMAN
NC score	0.204676 (rank : 31)	θ value	0.0736092 (rank : 27)
Query Neighborhood Hits	68	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NR56, O43311, O43797	Gene names	MBNL1, EXP, KIAA0428, MBNL
Domain Architecture
Description	Muscleblind-like protein (Triplet-expansion RNA-binding protein).

PAR12_HUMAN
NC score	0.131724 (rank : 32)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	68	Target Neighborhood Hits	42	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H0J9, Q9H610, Q9NP36, Q9NTI3	Gene names	PARP12, ZC3HDC1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

RBM22_HUMAN
NC score	0.131095 (rank : 33)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	68	Target Neighborhood Hits	189	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NW64, O95607	Gene names	RBM22
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22).

RBM22_MOUSE
NC score	0.131095 (rank : 34)	θ value	0.47712 (rank : 36)
Query Neighborhood Hits	68	Target Neighborhood Hits	189	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BHS3, Q3TJB0, Q9CXA0	Gene names	Rbm22
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22).

PAR12_MOUSE
NC score	0.128763 (rank : 35)	θ value	0.0330416 (rank : 21)
Query Neighborhood Hits	68	Target Neighborhood Hits	60	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BZ20, Q80VL6, Q8K333, Q8R3U2	Gene names	Parp12, Zc3hdc1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

R113B_HUMAN
NC score	0.115485 (rank : 36)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	68	Target Neighborhood Hits	165	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

R113A_HUMAN
NC score	0.106005 (rank : 37)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	68	Target Neighborhood Hits	177	Shared Neighborhood Hits	22
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

CNBP_HUMAN
NC score	0.101751 (rank : 38)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	68	Target Neighborhood Hits	196	Shared Neighborhood Hits	16
SwissProt Accessions	P62633, P20694, Q5QJR0, Q6PJI7, Q96NV3	Gene names	CNBP, ZNF9
Domain Architecture	No domain graphic available
Description	Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9).

CNBP_MOUSE
NC score	0.099704 (rank : 39)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	68	Target Neighborhood Hits	215	Shared Neighborhood Hits	16
SwissProt Accessions	P53996, Q80Y06, Q8BP23	Gene names	Cnbp, Cnbp1, Znf9
Domain Architecture	No domain graphic available
Description	Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9).

ZCH13_HUMAN
NC score	0.092974 (rank : 40)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	68	Target Neighborhood Hits	151	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WW36	Gene names	ZCCHC13
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 13.

Z3H7A_HUMAN
NC score	0.086236 (rank : 41)	θ value	0.125558 (rank : 29)
Query Neighborhood Hits	68	Target Neighborhood Hits	105	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

ZCHC3_HUMAN
NC score	0.081825 (rank : 42)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	68	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NUD5, Q6NT79	Gene names	ZCCHC3, C20orf99
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 3.

DUS3L_HUMAN
NC score	0.081472 (rank : 43)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	68	Target Neighborhood Hits	44	Shared Neighborhood Hits	20
SwissProt Accessions	Q96G46, Q96HM5, Q9BSU4, Q9H877, Q9NPR1	Gene names	DUS3L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

TRM1_HUMAN
NC score	0.077025 (rank : 44)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	68	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NXH9, O76103, Q548Y5, Q8WVA6	Gene names	TRMT1
Domain Architecture
Description	N(2),N(2)-dimethylguanosine tRNA methyltransferase (EC 2.1.1.32) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2- dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase).

RECQ4_MOUSE
NC score	0.072259 (rank : 45)	θ value	0.0148317 (rank : 20)
Query Neighborhood Hits	68	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

DHX57_HUMAN
NC score	0.066773 (rank : 46)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	68	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

ZCHC7_HUMAN
NC score	0.064902 (rank : 47)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	68	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N3Z6, Q5T0Q8, Q5T0Q9, Q5T0R0, Q8N2M1, Q8N4J2, Q8TBK8, Q9H648, Q9P0F0	Gene names	ZCCHC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 7.

DUS3L_MOUSE
NC score	0.063947 (rank : 48)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	68	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q91XI1, Q3TZQ1, Q7TT12	Gene names	Dus3l
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

DHX57_MOUSE
NC score	0.057157 (rank : 49)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	68	Target Neighborhood Hits	125	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

TRM1_MOUSE
NC score	0.052243 (rank : 50)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	68	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	Q3TX08, Q3TBY4	Gene names	Trmt1, D8Ertd812e
Domain Architecture	No domain graphic available
Description	N(2),N(2)-dimethylguanosine tRNA methyltransferase (EC 2.1.1.32) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2- dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase).

MAVS_HUMAN
NC score	0.052182 (rank : 51)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	68	Target Neighborhood Hits	271	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

PARPT_MOUSE
NC score	0.052068 (rank : 52)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	68	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

PARPT_HUMAN
NC score	0.051947 (rank : 53)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	68	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).

RBBP6_MOUSE
NC score	0.050151 (rank : 54)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	68	Target Neighborhood Hits	1014	Shared Neighborhood Hits	13
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SFRS7_HUMAN
NC score	0.049183 (rank : 55)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	68	Target Neighborhood Hits	191	Shared Neighborhood Hits	14
SwissProt Accessions	Q16629	Gene names	SFRS7
Domain Architecture
Description	Splicing factor, arginine/serine-rich 7 (Splicing factor 9G8).

SFRS7_MOUSE
NC score	0.049136 (rank : 56)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	68	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BL97, Q8BMC6, Q8BUR2, Q8R2N4, Q8R3E9, Q91YS1	Gene names	Sfrs7
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 7.

RBBP6_HUMAN
NC score	0.045233 (rank : 57)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	68	Target Neighborhood Hits	1135	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

ZCH14_MOUSE
NC score	0.036209 (rank : 58)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	68	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

ZCH14_HUMAN
NC score	0.034735 (rank : 59)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	68	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

ZCH12_HUMAN
NC score	0.034670 (rank : 60)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	68	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PEW1, Q6PID5, Q8N1C1	Gene names	ZCCHC12
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 12.

U2AFL_MOUSE
NC score	0.022200 (rank : 61)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	68	Target Neighborhood Hits	389	Shared Neighborhood Hits	9
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

RBM4_HUMAN
NC score	0.021737 (rank : 62)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	68	Target Neighborhood Hits	219	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BWF3, O02916, Q6P1P2, Q8WU85	Gene names	RBM4, RBM4A
Domain Architecture	No domain graphic available
Description	RNA-binding protein 4 (RNA-binding motif protein 4) (RNA-binding motif protein 4a) (Lark homolog) (hLark).

RBM4_MOUSE
NC score	0.021299 (rank : 63)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	68	Target Neighborhood Hits	223	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C7Q4, O08752, Q8BN66	Gene names	Rbm4, Rbm4a
Domain Architecture	No domain graphic available
Description	RNA-binding protein 4 (RNA-binding motif protein 4) (RNA-binding motif protein 4a) (Lark homolog) (mLark).

ERO1B_HUMAN
NC score	0.016484 (rank : 64)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	68	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q86YB8, Q8IZ11, Q9NR62	Gene names	ERO1LB
Domain Architecture	No domain graphic available
Description	ERO1-like protein beta precursor (EC 1.8.4.-) (ERO1-Lbeta) (Oxidoreductin-1-Lbeta) (Endoplasmic oxidoreductin-1-like protein B).

ERO1B_MOUSE
NC score	0.016440 (rank : 65)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	68	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R2E9	Gene names	Ero1lb
Domain Architecture	No domain graphic available
Description	ERO1-like protein beta precursor (EC 1.8.4.-) (ERO1-Lbeta) (Oxidoreductin-1-Lbeta) (Endoplasmic oxidoreductin-1-like protein B).

NCOA1_HUMAN
NC score	0.015207 (rank : 66)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	68	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

ECT2_HUMAN
NC score	0.013818 (rank : 67)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	68	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8V3, Q9NSV8, Q9NVW9	Gene names	ECT2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

GRN_HUMAN
NC score	0.008156 (rank : 68)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	68	Target Neighborhood Hits	268	Shared Neighborhood Hits	3
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

NELL1_HUMAN
NC score	0.001832 (rank : 69)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	68	Target Neighborhood Hits	451	Shared Neighborhood Hits	3
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

ZN615_HUMAN
NC score	-0.003211 (rank : 70)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	68	Target Neighborhood Hits	775	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N8J6	Gene names	ZNF615
Domain Architecture	No domain graphic available
Description	Zinc finger protein 615.