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Network neighborhood for query Sequence : PAR12_HUMAN

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PAR12_HUMAN
SwissProt Accessions	Q9H0J9, Q9H610, Q9NP36, Q9NTI3	Gene names	PARP12, ZC3HDC1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PAR12_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H0J9, Q9H610, Q9NP36, Q9NTI3	Gene names	PARP12, ZC3HDC1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

PAR12_MOUSE
θ value	0 (rank : 2)	NC score	0.995962 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BZ20, Q80VL6, Q8K333, Q8R3U2	Gene names	Parp12, Zc3hdc1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

ZCC2_HUMAN
θ value	3.82246e-75 (rank : 3)	NC score	0.894487 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

PARPT_MOUSE
θ value	4.11246e-53 (rank : 4)	NC score	0.853098 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

PARPT_HUMAN
θ value	1.01294e-51 (rank : 5)	NC score	0.855252 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).

PAR15_HUMAN
θ value	4.72714e-33 (rank : 6)	NC score	0.774790 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q460N3, Q8N1K3	Gene names	PARP15, BAL3
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 15 (EC 2.4.2.30) (PARP-15) (B-aggressive lymphoma protein 3).

PAR14_MOUSE
θ value	1.98606e-31 (rank : 7)	NC score	0.685490 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

PAR14_HUMAN
θ value	1.4233e-29 (rank : 8)	NC score	0.689062 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	Q460N5, Q460N4, Q8J027, Q9H9X9, Q9NV60, Q9ULF2	Gene names	PARP14, BAL2, KIAA1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (B aggressive lymphoma protein 2).

PAR10_HUMAN
θ value	1.24977e-17 (rank : 9)	NC score	0.655881 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	142	Shared Neighborhood Hits	14
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

TNKS2_HUMAN
θ value	1.25267e-09 (rank : 10)	NC score	0.148322 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	361	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

PARP9_HUMAN
θ value	3.08544e-08 (rank : 11)	NC score	0.527826 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IXQ6, Q8TCP3, Q9BZL8, Q9BZL9	Gene names	PARP9, BAL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein).

PARP9_MOUSE
θ value	9.92553e-07 (rank : 12)	NC score	0.502515 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CAS9, Q99LF9	Gene names	Parp9, Bal
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein homolog).

TNKS1_HUMAN
θ value	2.44474e-05 (rank : 13)	NC score	0.124510 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	477	Shared Neighborhood Hits	12
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

DHX57_HUMAN
θ value	0.0330416 (rank : 14)	NC score	0.072112 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	109	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

MKRN1_HUMAN
θ value	0.0563607 (rank : 15)	NC score	0.130130 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	141	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MKRN1_MOUSE
θ value	0.0563607 (rank : 16)	NC score	0.131636 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	141	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

MKRN3_HUMAN
θ value	0.0961366 (rank : 17)	NC score	0.121577 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	165	Shared Neighborhood Hits	24
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

MKRN3_MOUSE
θ value	0.0961366 (rank : 18)	NC score	0.123029 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	137	Shared Neighborhood Hits	26
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

ZC3H3_HUMAN
θ value	0.0961366 (rank : 19)	NC score	0.138484 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	159	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZC3H3_MOUSE
θ value	0.0961366 (rank : 20)	NC score	0.132491 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	188	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZC3H6_HUMAN
θ value	0.0961366 (rank : 21)	NC score	0.125874 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	228	Shared Neighborhood Hits	30
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ZC3H6_MOUSE
θ value	0.163984 (rank : 22)	NC score	0.122850 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	239	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

CPSF4_HUMAN
θ value	0.21417 (rank : 23)	NC score	0.131724 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	O95639, Q86TF8, Q9BTW6	Gene names	CPSF4, CPSF30, NAR, NEB1
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog).

MKRN2_HUMAN
θ value	0.21417 (rank : 24)	NC score	0.130956 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	129	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

TTP_MOUSE
θ value	0.21417 (rank : 25)	NC score	0.104693 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	75	Shared Neighborhood Hits	22
SwissProt Accessions	P22893, P11520	Gene names	Zfp36, Tis11, Tis11a
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (TPA-induced sequence 11).

DHX57_MOUSE
θ value	0.279714 (rank : 26)	NC score	0.053036 (rank : 45)
Query Neighborhood Hits	42	Target Neighborhood Hits	125	Shared Neighborhood Hits	29
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

MKRN2_MOUSE
θ value	0.279714 (rank : 27)	NC score	0.129799 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	130	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

NUPL2_HUMAN
θ value	0.365318 (rank : 28)	NC score	0.100505 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	37	Shared Neighborhood Hits	17
SwissProt Accessions	O15504, Q49AE7, Q9BS49	Gene names	NUPL2, CG1
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1) (hCG1) (NUP42 homolog).

NUPL2_MOUSE
θ value	0.365318 (rank : 29)	NC score	0.093345 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	54	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CIC2, Q8BJX3, Q8BVP7, Q924S0	Gene names	Nupl2
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1).

CS007_HUMAN
θ value	1.06291 (rank : 30)	NC score	0.094154 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	401	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CS007_MOUSE
θ value	1.06291 (rank : 31)	NC score	0.086739 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	464	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

MKRN4_HUMAN
θ value	1.06291 (rank : 32)	NC score	0.118127 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	147	Shared Neighborhood Hits	26
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

UBP48_MOUSE
θ value	1.38821 (rank : 33)	NC score	0.013428 (rank : 48)
Query Neighborhood Hits	42	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

TTP_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.070976 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	86	Shared Neighborhood Hits	23
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

RBM22_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.054247 (rank : 43)
Query Neighborhood Hits	42	Target Neighborhood Hits	189	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NW64, O95607	Gene names	RBM22
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22).

RBM22_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.054247 (rank : 44)
Query Neighborhood Hits	42	Target Neighborhood Hits	189	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BHS3, Q3TJB0, Q9CXA0	Gene names	Rbm22
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22).

CP3AG_MOUSE
θ value	5.27518 (rank : 37)	NC score	0.003405 (rank : 50)
Query Neighborhood Hits	42	Target Neighborhood Hits	119	Shared Neighborhood Hits	2
SwissProt Accessions	Q64481	Gene names	Cyp3a16, Cyp3a-16
Domain Architecture
Description	Cytochrome P450 3A16 (EC 1.14.14.1) (CYPIIIA16).

CPSF4_MOUSE
θ value	5.27518 (rank : 38)	NC score	0.091128 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	58	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BQZ5, O54930	Gene names	Cpsf4, Cpsf30
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K).

U2AFL_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.008184 (rank : 49)
Query Neighborhood Hits	42	Target Neighborhood Hits	389	Shared Neighborhood Hits	7
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

ZC3H8_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.085635 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	57	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N5P1, Q9BZ75	Gene names	ZC3H8, ZC3HDC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8.

ZGPAT_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.034617 (rank : 46)
Query Neighborhood Hits	42	Target Neighborhood Hits	97	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N5A5, Q5JWI9, Q8NC55, Q96JI0, Q96JU4, Q9H401	Gene names	ZGPAT, KIAA1847, ZC3H9, ZC3HDC9
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein (Zinc finger CCCH domain-containing protein 9).

ZGPAT_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.031754 (rank : 47)
Query Neighborhood Hits	42	Target Neighborhood Hits	107	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VDM1, Q8BWW2	Gene names	Zgpat
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein.

H2AW_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.056259 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P0M6, Q5SQT2	Gene names	H2AFY2, MACROH2A2
Domain Architecture
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AW_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.055440 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CCK0, Q3TNT4, Q925I6	Gene names	H2afy2, H2afy3
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AY_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.071810 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	O75367, O75377, Q503A8, Q7Z5E3, Q96D41, Q9H8P3, Q9UP96	Gene names	H2AFY, MACROH2A1
Domain Architecture
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205).

H2AY_MOUSE
θ value	θ > 10 (rank : 46)	NC score	0.071537 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZQ8, Q91VZ2, Q9QZQ7	Gene names	H2afy
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y).

LRP16_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.159439 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BQ69, Q9UH96	Gene names	LRP16
Domain Architecture
Description	Protein LRP16.

LRP16_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.153410 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q922B1	Gene names	Lrp16
Domain Architecture
Description	Protein LRP16.

PARP3_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.085323 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	30	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

ZC3H8_MOUSE
θ value	θ > 10 (rank : 50)	NC score	0.075273 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JJ48, Q80X92	Gene names	Zc3h8, Fliz1, Zc3hdc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8 (Fetal liver zinc finger protein 1).

Hits sorted by NC score

PAR12_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H0J9, Q9H610, Q9NP36, Q9NTI3	Gene names	PARP12, ZC3HDC1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

PAR12_MOUSE
NC score	0.995962 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BZ20, Q80VL6, Q8K333, Q8R3U2	Gene names	Parp12, Zc3hdc1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

ZCC2_HUMAN
NC score	0.894487 (rank : 3)	θ value	3.82246e-75 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

PARPT_HUMAN
NC score	0.855252 (rank : 4)	θ value	1.01294e-51 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).

PARPT_MOUSE
NC score	0.853098 (rank : 5)	θ value	4.11246e-53 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

PAR15_HUMAN
NC score	0.774790 (rank : 6)	θ value	4.72714e-33 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q460N3, Q8N1K3	Gene names	PARP15, BAL3
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 15 (EC 2.4.2.30) (PARP-15) (B-aggressive lymphoma protein 3).

PAR14_HUMAN
NC score	0.689062 (rank : 7)	θ value	1.4233e-29 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	Q460N5, Q460N4, Q8J027, Q9H9X9, Q9NV60, Q9ULF2	Gene names	PARP14, BAL2, KIAA1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (B aggressive lymphoma protein 2).

PAR14_MOUSE
NC score	0.685490 (rank : 8)	θ value	1.98606e-31 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

PAR10_HUMAN
NC score	0.655881 (rank : 9)	θ value	1.24977e-17 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	142	Shared Neighborhood Hits	14
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

PARP9_HUMAN
NC score	0.527826 (rank : 10)	θ value	3.08544e-08 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IXQ6, Q8TCP3, Q9BZL8, Q9BZL9	Gene names	PARP9, BAL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein).

PARP9_MOUSE
NC score	0.502515 (rank : 11)	θ value	9.92553e-07 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CAS9, Q99LF9	Gene names	Parp9, Bal
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein homolog).

LRP16_HUMAN
NC score	0.159439 (rank : 12)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	42	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BQ69, Q9UH96	Gene names	LRP16
Domain Architecture
Description	Protein LRP16.

LRP16_MOUSE
NC score	0.153410 (rank : 13)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	42	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q922B1	Gene names	Lrp16
Domain Architecture
Description	Protein LRP16.

TNKS2_HUMAN
NC score	0.148322 (rank : 14)	θ value	1.25267e-09 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	361	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ZC3H3_HUMAN
NC score	0.138484 (rank : 15)	θ value	0.0961366 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	159	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZC3H3_MOUSE
NC score	0.132491 (rank : 16)	θ value	0.0961366 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	188	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

CPSF4_HUMAN
NC score	0.131724 (rank : 17)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	O95639, Q86TF8, Q9BTW6	Gene names	CPSF4, CPSF30, NAR, NEB1
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog).

MKRN1_MOUSE
NC score	0.131636 (rank : 18)	θ value	0.0563607 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	141	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

MKRN2_HUMAN
NC score	0.130956 (rank : 19)	θ value	0.21417 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	129	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN1_HUMAN
NC score	0.130130 (rank : 20)	θ value	0.0563607 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	141	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MKRN2_MOUSE
NC score	0.129799 (rank : 21)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	130	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

ZC3H6_HUMAN
NC score	0.125874 (rank : 22)	θ value	0.0961366 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	228	Shared Neighborhood Hits	30
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

TNKS1_HUMAN
NC score	0.124510 (rank : 23)	θ value	2.44474e-05 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	477	Shared Neighborhood Hits	12
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

MKRN3_MOUSE
NC score	0.123029 (rank : 24)	θ value	0.0961366 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	137	Shared Neighborhood Hits	26
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

ZC3H6_MOUSE
NC score	0.122850 (rank : 25)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	239	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

MKRN3_HUMAN
NC score	0.121577 (rank : 26)	θ value	0.0961366 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	165	Shared Neighborhood Hits	24
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

MKRN4_HUMAN
NC score	0.118127 (rank : 27)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	147	Shared Neighborhood Hits	26
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

TTP_MOUSE
NC score	0.104693 (rank : 28)	θ value	0.21417 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	75	Shared Neighborhood Hits	22
SwissProt Accessions	P22893, P11520	Gene names	Zfp36, Tis11, Tis11a
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (TPA-induced sequence 11).

NUPL2_HUMAN
NC score	0.100505 (rank : 29)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	37	Shared Neighborhood Hits	17
SwissProt Accessions	O15504, Q49AE7, Q9BS49	Gene names	NUPL2, CG1
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1) (hCG1) (NUP42 homolog).

CS007_HUMAN
NC score	0.094154 (rank : 30)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	401	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

NUPL2_MOUSE
NC score	0.093345 (rank : 31)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	54	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CIC2, Q8BJX3, Q8BVP7, Q924S0	Gene names	Nupl2
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1).

CPSF4_MOUSE
NC score	0.091128 (rank : 32)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	58	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BQZ5, O54930	Gene names	Cpsf4, Cpsf30
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 30 kDa subunit (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K).

CS007_MOUSE
NC score	0.086739 (rank : 33)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	464	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

ZC3H8_HUMAN
NC score	0.085635 (rank : 34)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	57	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N5P1, Q9BZ75	Gene names	ZC3H8, ZC3HDC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8.

PARP3_HUMAN
NC score	0.085323 (rank : 35)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	42	Target Neighborhood Hits	30	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

ZC3H8_MOUSE
NC score	0.075273 (rank : 36)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	42	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JJ48, Q80X92	Gene names	Zc3h8, Fliz1, Zc3hdc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8 (Fetal liver zinc finger protein 1).

DHX57_HUMAN
NC score	0.072112 (rank : 37)	θ value	0.0330416 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	109	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

H2AY_HUMAN
NC score	0.071810 (rank : 38)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	42	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	O75367, O75377, Q503A8, Q7Z5E3, Q96D41, Q9H8P3, Q9UP96	Gene names	H2AFY, MACROH2A1
Domain Architecture
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205).

H2AY_MOUSE
NC score	0.071537 (rank : 39)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	42	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZQ8, Q91VZ2, Q9QZQ7	Gene names	H2afy
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y).

TTP_HUMAN
NC score	0.070976 (rank : 40)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	86	Shared Neighborhood Hits	23
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

H2AW_HUMAN
NC score	0.056259 (rank : 41)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	42	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P0M6, Q5SQT2	Gene names	H2AFY2, MACROH2A2
Domain Architecture
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AW_MOUSE
NC score	0.055440 (rank : 42)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	42	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CCK0, Q3TNT4, Q925I6	Gene names	H2afy2, H2afy3
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

RBM22_HUMAN
NC score	0.054247 (rank : 43)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	189	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NW64, O95607	Gene names	RBM22
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22).

RBM22_MOUSE
NC score	0.054247 (rank : 44)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	189	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BHS3, Q3TJB0, Q9CXA0	Gene names	Rbm22
Domain Architecture	No domain graphic available
Description	Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22).

DHX57_MOUSE
NC score	0.053036 (rank : 45)	θ value	0.279714 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	125	Shared Neighborhood Hits	29
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

ZGPAT_HUMAN
NC score	0.034617 (rank : 46)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	97	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N5A5, Q5JWI9, Q8NC55, Q96JI0, Q96JU4, Q9H401	Gene names	ZGPAT, KIAA1847, ZC3H9, ZC3HDC9
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein (Zinc finger CCCH domain-containing protein 9).

ZGPAT_MOUSE
NC score	0.031754 (rank : 47)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	107	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VDM1, Q8BWW2	Gene names	Zgpat
Domain Architecture
Description	Zinc finger CCCH-type with G patch domain protein.

UBP48_MOUSE
NC score	0.013428 (rank : 48)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

U2AFL_MOUSE
NC score	0.008184 (rank : 49)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	389	Shared Neighborhood Hits	7
SwissProt Accessions	Q64707	Gene names	Zrsr1, Sp2, Sp2-7, U2af1-rs1, U2af1l1
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1) (SP2).

CP3AG_MOUSE
NC score	0.003405 (rank : 50)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	119	Shared Neighborhood Hits	2
SwissProt Accessions	Q64481	Gene names	Cyp3a16, Cyp3a-16
Domain Architecture
Description	Cytochrome P450 3A16 (EC 1.14.14.1) (CYPIIIA16).