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Network neighborhood for query Sequence : ZCC2_HUMAN

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ZCC2_HUMAN
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ZCC2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

PAR12_HUMAN
θ value	3.82246e-75 (rank : 2)	NC score	0.894487 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	42	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H0J9, Q9H610, Q9NP36, Q9NTI3	Gene names	PARP12, ZC3HDC1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

PAR12_MOUSE
θ value	9.41505e-74 (rank : 3)	NC score	0.892689 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZ20, Q80VL6, Q8K333, Q8R3U2	Gene names	Parp12, Zc3hdc1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

PARPT_HUMAN
θ value	2.59387e-31 (rank : 4)	NC score	0.795209 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).

PARPT_MOUSE
θ value	2.86786e-30 (rank : 5)	NC score	0.794226 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

PAR15_HUMAN
θ value	5.42112e-21 (rank : 6)	NC score	0.729182 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q460N3, Q8N1K3	Gene names	PARP15, BAL3
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 15 (EC 2.4.2.30) (PARP-15) (B-aggressive lymphoma protein 3).

PAR14_MOUSE
θ value	6.62687e-19 (rank : 7)	NC score	0.641376 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	113	Shared Neighborhood Hits	14
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

PAR14_HUMAN
θ value	1.16975e-15 (rank : 8)	NC score	0.639880 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	Q460N5, Q460N4, Q8J027, Q9H9X9, Q9NV60, Q9ULF2	Gene names	PARP14, BAL2, KIAA1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (B aggressive lymphoma protein 2).

PARP9_HUMAN
θ value	3.29651e-10 (rank : 9)	NC score	0.539758 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IXQ6, Q8TCP3, Q9BZL8, Q9BZL9	Gene names	PARP9, BAL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein).

PARP9_MOUSE
θ value	9.59137e-10 (rank : 10)	NC score	0.520146 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CAS9, Q99LF9	Gene names	Parp9, Bal
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein homolog).

PAR10_HUMAN
θ value	2.13673e-09 (rank : 11)	NC score	0.595080 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	142	Shared Neighborhood Hits	14
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

TNKS2_HUMAN
θ value	8.40245e-06 (rank : 12)	NC score	0.137830 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	361	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

TNKS1_HUMAN
θ value	0.00134147 (rank : 13)	NC score	0.115295 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	477	Shared Neighborhood Hits	18
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

PARP3_HUMAN
θ value	0.00665767 (rank : 14)	NC score	0.137334 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

SRRM2_MOUSE
θ value	0.0330416 (rank : 15)	NC score	0.041721 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	1470	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

FILA_HUMAN
θ value	0.0563607 (rank : 16)	NC score	0.044826 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	685	Shared Neighborhood Hits	11
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

GIT2_MOUSE
θ value	0.279714 (rank : 17)	NC score	0.041457 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	323	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

HUWE1_HUMAN
θ value	0.279714 (rank : 18)	NC score	0.034142 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	443	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	0.279714 (rank : 19)	NC score	0.034096 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	406	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

PARP4_HUMAN
θ value	0.47712 (rank : 20)	NC score	0.062668 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

GIT2_HUMAN
θ value	0.62314 (rank : 21)	NC score	0.038585 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	381	Shared Neighborhood Hits	6
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

M4K4_HUMAN
θ value	0.62314 (rank : 22)	NC score	0.006305 (rank : 49)
Query Neighborhood Hits	47	Target Neighborhood Hits	1589	Shared Neighborhood Hits	5
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
θ value	0.62314 (rank : 23)	NC score	0.006962 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	1560	Shared Neighborhood Hits	10
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MAGD1_MOUSE
θ value	0.62314 (rank : 24)	NC score	0.019583 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYH6, Q543L6, Q99PB5, Q9CYX1	Gene names	Maged1, Nrage
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (Dlxin-1).

SON_MOUSE
θ value	1.06291 (rank : 25)	NC score	0.024006 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	957	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TMCC2_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.028869 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	227	Shared Neighborhood Hits	6
SwissProt Accessions	O75069, Q6ZN09	Gene names	TMCC2, KIAA0481
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 2 (Cerebral protein 11).

SVIL_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.022402 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	439	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

LPXN_MOUSE
θ value	3.0926 (rank : 28)	NC score	0.010212 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	227	Shared Neighborhood Hits	3
SwissProt Accessions	Q99N69	Gene names	Lpxn
Domain Architecture	No domain graphic available
Description	Leupaxin.

TMCC2_MOUSE
θ value	3.0926 (rank : 29)	NC score	0.025267 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	227	Shared Neighborhood Hits	4
SwissProt Accessions	Q80W04, Q6A061	Gene names	Tmcc2, Kiaa0481
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 2.

LDB2_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.017567 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	O55203, O55205, Q6AXE6	Gene names	Ldb2, Clim1
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 2 (Carboxyl-terminal LIM domain-binding protein 1) (CLIM-1) (LIM-domain-binding factor CLIM1).

MUC1_MOUSE
θ value	4.03905 (rank : 31)	NC score	0.025701 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	388	Shared Neighborhood Hits	8
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

SPEG_MOUSE
θ value	4.03905 (rank : 32)	NC score	0.003851 (rank : 52)
Query Neighborhood Hits	47	Target Neighborhood Hits	1959	Shared Neighborhood Hits	14
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TBC16_HUMAN
θ value	4.03905 (rank : 33)	NC score	0.017561 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TBP0	Gene names	TBC1D16
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 16.

CSF1R_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.002183 (rank : 53)
Query Neighborhood Hits	47	Target Neighborhood Hits	983	Shared Neighborhood Hits	5
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

NID1_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.004650 (rank : 51)
Query Neighborhood Hits	47	Target Neighborhood Hits	329	Shared Neighborhood Hits	2
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

SYN3_MOUSE
θ value	5.27518 (rank : 36)	NC score	0.014017 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

LMO6_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.007795 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	337	Shared Neighborhood Hits	3
SwissProt Accessions	O43900, O76007	Gene names	LMO6
Domain Architecture
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

SFRS2_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.013042 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	222	Shared Neighborhood Hits	7
SwissProt Accessions	Q01130	Gene names	SFRS2
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264).

SFRS2_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.013042 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	222	Shared Neighborhood Hits	7
SwissProt Accessions	Q62093, Q542L3, Q60701	Gene names	Sfrs2, Pr264, Sfrs10
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264) (Putative myelin regulatory factor 1) (MRF-1).

SFRS6_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.014671 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	247	Shared Neighborhood Hits	8
SwissProt Accessions	Q13247, Q13244, Q13245, Q96J06, Q9UJB8, Q9Y3N7	Gene names	SFRS6, SRP55
Domain Architecture
Description	Splicing factor, arginine/serine-rich 6 (Pre-mRNA-splicing factor SRP55).

ATX7_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.012924 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	351	Shared Neighborhood Hits	5
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

CROP_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.011363 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	402	Shared Neighborhood Hits	5
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

DTX2_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.009533 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

LZTS1_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.005057 (rank : 50)
Query Neighborhood Hits	47	Target Neighborhood Hits	540	Shared Neighborhood Hits	3
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

RPC8_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.015726 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D2C6, Q91XE5	Gene names	Polr3h
Domain Architecture
Description	DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide (EC 2.7.7.6) (RPC8).

SFRS4_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.014143 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TACC3_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.007244 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	779	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

H2AW_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.054960 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P0M6, Q5SQT2	Gene names	H2AFY2, MACROH2A2
Domain Architecture
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AW_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.053783 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CCK0, Q3TNT4, Q925I6	Gene names	H2afy2, H2afy3
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AY_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.069838 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	O75367, O75377, Q503A8, Q7Z5E3, Q96D41, Q9H8P3, Q9UP96	Gene names	H2AFY, MACROH2A1
Domain Architecture
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205).

H2AY_MOUSE
θ value	θ > 10 (rank : 51)	NC score	0.069455 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZQ8, Q91VZ2, Q9QZQ7	Gene names	H2afy
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y).

LRP16_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.157623 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BQ69, Q9UH96	Gene names	LRP16
Domain Architecture
Description	Protein LRP16.

LRP16_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.151114 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q922B1	Gene names	Lrp16
Domain Architecture
Description	Protein LRP16.

Hits sorted by NC score

ZCC2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

PAR12_HUMAN
NC score	0.894487 (rank : 2)	θ value	3.82246e-75 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	42	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H0J9, Q9H610, Q9NP36, Q9NTI3	Gene names	PARP12, ZC3HDC1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

PAR12_MOUSE
NC score	0.892689 (rank : 3)	θ value	9.41505e-74 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZ20, Q80VL6, Q8K333, Q8R3U2	Gene names	Parp12, Zc3hdc1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 12 (EC 2.4.2.30) (PARP-12) (Zinc finger CCCH domain-containing protein 1).

PARPT_HUMAN
NC score	0.795209 (rank : 4)	θ value	2.59387e-31 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).

PARPT_MOUSE
NC score	0.794226 (rank : 5)	θ value	2.86786e-30 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

PAR15_HUMAN
NC score	0.729182 (rank : 6)	θ value	5.42112e-21 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q460N3, Q8N1K3	Gene names	PARP15, BAL3
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 15 (EC 2.4.2.30) (PARP-15) (B-aggressive lymphoma protein 3).

PAR14_MOUSE
NC score	0.641376 (rank : 7)	θ value	6.62687e-19 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	113	Shared Neighborhood Hits	14
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

PAR14_HUMAN
NC score	0.639880 (rank : 8)	θ value	1.16975e-15 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	Q460N5, Q460N4, Q8J027, Q9H9X9, Q9NV60, Q9ULF2	Gene names	PARP14, BAL2, KIAA1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (B aggressive lymphoma protein 2).

PAR10_HUMAN
NC score	0.595080 (rank : 9)	θ value	2.13673e-09 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	142	Shared Neighborhood Hits	14
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

PARP9_HUMAN
NC score	0.539758 (rank : 10)	θ value	3.29651e-10 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IXQ6, Q8TCP3, Q9BZL8, Q9BZL9	Gene names	PARP9, BAL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein).

PARP9_MOUSE
NC score	0.520146 (rank : 11)	θ value	9.59137e-10 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CAS9, Q99LF9	Gene names	Parp9, Bal
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein homolog).

LRP16_HUMAN
NC score	0.157623 (rank : 12)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	47	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BQ69, Q9UH96	Gene names	LRP16
Domain Architecture
Description	Protein LRP16.

LRP16_MOUSE
NC score	0.151114 (rank : 13)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	47	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q922B1	Gene names	Lrp16
Domain Architecture
Description	Protein LRP16.

TNKS2_HUMAN
NC score	0.137830 (rank : 14)	θ value	8.40245e-06 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	361	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

PARP3_HUMAN
NC score	0.137334 (rank : 15)	θ value	0.00665767 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

TNKS1_HUMAN
NC score	0.115295 (rank : 16)	θ value	0.00134147 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	477	Shared Neighborhood Hits	18
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

H2AY_HUMAN
NC score	0.069838 (rank : 17)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	47	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	O75367, O75377, Q503A8, Q7Z5E3, Q96D41, Q9H8P3, Q9UP96	Gene names	H2AFY, MACROH2A1
Domain Architecture
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205).

H2AY_MOUSE
NC score	0.069455 (rank : 18)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	47	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZQ8, Q91VZ2, Q9QZQ7	Gene names	H2afy
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y).

PARP4_HUMAN
NC score	0.062668 (rank : 19)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

H2AW_HUMAN
NC score	0.054960 (rank : 20)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P0M6, Q5SQT2	Gene names	H2AFY2, MACROH2A2
Domain Architecture
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AW_MOUSE
NC score	0.053783 (rank : 21)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	47	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CCK0, Q3TNT4, Q925I6	Gene names	H2afy2, H2afy3
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

FILA_HUMAN
NC score	0.044826 (rank : 22)	θ value	0.0563607 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	685	Shared Neighborhood Hits	11
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

SRRM2_MOUSE
NC score	0.041721 (rank : 23)	θ value	0.0330416 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	1470	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

GIT2_MOUSE
NC score	0.041457 (rank : 24)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	323	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

GIT2_HUMAN
NC score	0.038585 (rank : 25)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	381	Shared Neighborhood Hits	6
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

HUWE1_HUMAN
NC score	0.034142 (rank : 26)	θ value	0.279714 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	443	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
NC score	0.034096 (rank : 27)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	406	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

TMCC2_HUMAN
NC score	0.028869 (rank : 28)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	227	Shared Neighborhood Hits	6
SwissProt Accessions	O75069, Q6ZN09	Gene names	TMCC2, KIAA0481
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 2 (Cerebral protein 11).

MUC1_MOUSE
NC score	0.025701 (rank : 29)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	388	Shared Neighborhood Hits	8
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

TMCC2_MOUSE
NC score	0.025267 (rank : 30)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	227	Shared Neighborhood Hits	4
SwissProt Accessions	Q80W04, Q6A061	Gene names	Tmcc2, Kiaa0481
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 2.

SON_MOUSE
NC score	0.024006 (rank : 31)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	957	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SVIL_MOUSE
NC score	0.022402 (rank : 32)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	439	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

MAGD1_MOUSE
NC score	0.019583 (rank : 33)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYH6, Q543L6, Q99PB5, Q9CYX1	Gene names	Maged1, Nrage
Domain Architecture
Description	Melanoma-associated antigen D1 (MAGE-D1 antigen) (Neurotrophin receptor-interacting MAGE homolog) (Dlxin-1).

LDB2_MOUSE
NC score	0.017567 (rank : 34)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	O55203, O55205, Q6AXE6	Gene names	Ldb2, Clim1
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 2 (Carboxyl-terminal LIM domain-binding protein 1) (CLIM-1) (LIM-domain-binding factor CLIM1).

TBC16_HUMAN
NC score	0.017561 (rank : 35)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TBP0	Gene names	TBC1D16
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 16.

RPC8_MOUSE
NC score	0.015726 (rank : 36)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D2C6, Q91XE5	Gene names	Polr3h
Domain Architecture
Description	DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide (EC 2.7.7.6) (RPC8).

SFRS6_HUMAN
NC score	0.014671 (rank : 37)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	247	Shared Neighborhood Hits	8
SwissProt Accessions	Q13247, Q13244, Q13245, Q96J06, Q9UJB8, Q9Y3N7	Gene names	SFRS6, SRP55
Domain Architecture
Description	Splicing factor, arginine/serine-rich 6 (Pre-mRNA-splicing factor SRP55).

SFRS4_MOUSE
NC score	0.014143 (rank : 38)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

SYN3_MOUSE
NC score	0.014017 (rank : 39)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

SFRS2_HUMAN
NC score	0.013042 (rank : 40)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	222	Shared Neighborhood Hits	7
SwissProt Accessions	Q01130	Gene names	SFRS2
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264).

SFRS2_MOUSE
NC score	0.013042 (rank : 41)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	222	Shared Neighborhood Hits	7
SwissProt Accessions	Q62093, Q542L3, Q60701	Gene names	Sfrs2, Pr264, Sfrs10
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264) (Putative myelin regulatory factor 1) (MRF-1).

ATX7_HUMAN
NC score	0.012924 (rank : 42)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	351	Shared Neighborhood Hits	5
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

CROP_HUMAN
NC score	0.011363 (rank : 43)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	402	Shared Neighborhood Hits	5
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

LPXN_MOUSE
NC score	0.010212 (rank : 44)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	227	Shared Neighborhood Hits	3
SwissProt Accessions	Q99N69	Gene names	Lpxn
Domain Architecture	No domain graphic available
Description	Leupaxin.

DTX2_MOUSE
NC score	0.009533 (rank : 45)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

LMO6_HUMAN
NC score	0.007795 (rank : 46)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	337	Shared Neighborhood Hits	3
SwissProt Accessions	O43900, O76007	Gene names	LMO6
Domain Architecture
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

TACC3_HUMAN
NC score	0.007244 (rank : 47)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	779	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

M4K4_MOUSE
NC score	0.006962 (rank : 48)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	1560	Shared Neighborhood Hits	10
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_HUMAN
NC score	0.006305 (rank : 49)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	1589	Shared Neighborhood Hits	5
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

LZTS1_MOUSE
NC score	0.005057 (rank : 50)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	540	Shared Neighborhood Hits	3
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

NID1_HUMAN
NC score	0.004650 (rank : 51)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	329	Shared Neighborhood Hits	2
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

SPEG_MOUSE
NC score	0.003851 (rank : 52)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	1959	Shared Neighborhood Hits	14
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CSF1R_MOUSE
NC score	0.002183 (rank : 53)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	983	Shared Neighborhood Hits	5
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).