Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : PARP4_HUMAN

For an explanation of this page, click here

PARP4_HUMAN
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PARP4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	93	Target Neighborhood Hits	93	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

LHR2A_MOUSE
θ value	3.85808e-43 (rank : 2)	NC score	0.641603 (rank : 2)
Query Neighborhood Hits	93	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q99KC8, Q3TTU2, Q6UN22, Q8BHA8, Q9CTV9	Gene names	Loh11cr2a
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog.

LHR2A_HUMAN
θ value	5.76516e-39 (rank : 3)	NC score	0.630753 (rank : 3)
Query Neighborhood Hits	93	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	O00534, Q6UN19, Q6UN20, Q9BVF8	Gene names	LOH11CR2A, BCSC1
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein (Breast cancer suppressor candidate 1) (BCSC-1).

PARP1_HUMAN
θ value	3.07116e-24 (rank : 4)	NC score	0.557600 (rank : 5)
Query Neighborhood Hits	93	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

PARP1_MOUSE
θ value	4.43474e-23 (rank : 5)	NC score	0.548923 (rank : 7)
Query Neighborhood Hits	93	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

PARP2_HUMAN
θ value	3.75424e-22 (rank : 6)	NC score	0.566220 (rank : 4)
Query Neighborhood Hits	93	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

PARP2_MOUSE
θ value	5.07402e-19 (rank : 7)	NC score	0.551828 (rank : 6)
Query Neighborhood Hits	93	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

PARP3_HUMAN
θ value	1.09485e-13 (rank : 8)	NC score	0.538458 (rank : 8)
Query Neighborhood Hits	93	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

ITIH4_HUMAN
θ value	5.08577e-11 (rank : 9)	NC score	0.344964 (rank : 9)
Query Neighborhood Hits	93	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	Q14624, Q15135, Q9P190, Q9UQ54	Gene names	ITIH4, IHRP, ITIHL1, PK120
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H4 precursor (ITI heavy chain H4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (PK-120) (GP120) [Contains: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha- trypsin inhibitor heavy chain H4].

ITIH3_HUMAN
θ value	2.21117e-06 (rank : 10)	NC score	0.287804 (rank : 10)
Query Neighborhood Hits	93	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	Q06033, Q99085	Gene names	ITIH3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3) (Serum-derived hyaluronan-associated protein) (SHAP).

ITIH3_MOUSE
θ value	2.44474e-05 (rank : 11)	NC score	0.280170 (rank : 12)
Query Neighborhood Hits	93	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q61704	Gene names	Itih3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3).

TNKS2_HUMAN
θ value	3.19293e-05 (rank : 12)	NC score	0.076273 (rank : 21)
Query Neighborhood Hits	93	Target Neighborhood Hits	361	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

TNKS1_HUMAN
θ value	5.44631e-05 (rank : 13)	NC score	0.081017 (rank : 20)
Query Neighborhood Hits	93	Target Neighborhood Hits	477	Shared Neighborhood Hits	19
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ITIH1_MOUSE
θ value	0.000270298 (rank : 14)	NC score	0.275438 (rank : 13)
Query Neighborhood Hits	93	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	Q61702	Gene names	Itih1
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H1 precursor (ITI heavy chain H1) (Inter-alpha-inhibitor heavy chain 1).

ITIH1_HUMAN
θ value	0.000602161 (rank : 15)	NC score	0.286447 (rank : 11)
Query Neighborhood Hits	93	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P19827, P78455, Q01746	Gene names	ITIH1, IGHEP1
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H1 precursor (ITI heavy chain H1) (Inter-alpha-inhibitor heavy chain 1) (Inter-alpha-trypsin inhibitor complex component III) (Serum-derived hyaluronan-associated protein) (SHAP).

MUC1_HUMAN
θ value	0.00134147 (rank : 16)	NC score	0.059614 (rank : 26)
Query Neighborhood Hits	93	Target Neighborhood Hits	975	Shared Neighborhood Hits	34
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

RPB1_HUMAN
θ value	0.00134147 (rank : 17)	NC score	0.106440 (rank : 16)
Query Neighborhood Hits	93	Target Neighborhood Hits	362	Shared Neighborhood Hits	11
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	0.00134147 (rank : 18)	NC score	0.106422 (rank : 17)
Query Neighborhood Hits	93	Target Neighborhood Hits	363	Shared Neighborhood Hits	11
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

ITIH2_MOUSE
θ value	0.00175202 (rank : 19)	NC score	0.247242 (rank : 14)
Query Neighborhood Hits	93	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	Q61703	Gene names	Itih2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2).

TSH1_HUMAN
θ value	0.0330416 (rank : 20)	NC score	0.038140 (rank : 37)
Query Neighborhood Hits	93	Target Neighborhood Hits	558	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

CCDC4_HUMAN
θ value	0.0431538 (rank : 21)	NC score	0.102755 (rank : 18)
Query Neighborhood Hits	93	Target Neighborhood Hits	104	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZU67, Q58A26, Q58A27	Gene names	CCDC4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 4.

CN032_MOUSE
θ value	0.0431538 (rank : 22)	NC score	0.098698 (rank : 19)
Query Neighborhood Hits	93	Target Neighborhood Hits	233	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

ITIH2_HUMAN
θ value	0.0431538 (rank : 23)	NC score	0.227211 (rank : 15)
Query Neighborhood Hits	93	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	P19823, Q14659, Q15484	Gene names	ITIH2, IGHEP2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2) (Inter-alpha-trypsin inhibitor complex component II) (Serum-derived hyaluronan-associated protein) (SHAP).

MYH8_MOUSE
θ value	0.279714 (rank : 24)	NC score	0.025725 (rank : 51)
Query Neighborhood Hits	93	Target Neighborhood Hits	1600	Shared Neighborhood Hits	20
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NACAM_MOUSE
θ value	0.47712 (rank : 25)	NC score	0.048274 (rank : 32)
Query Neighborhood Hits	93	Target Neighborhood Hits	1866	Shared Neighborhood Hits	41
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ZCC2_HUMAN
θ value	0.47712 (rank : 26)	NC score	0.062668 (rank : 25)
Query Neighborhood Hits	93	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

M3K6_HUMAN
θ value	0.813845 (rank : 27)	NC score	0.003583 (rank : 92)
Query Neighborhood Hits	93	Target Neighborhood Hits	889	Shared Neighborhood Hits	5
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

MLL4_HUMAN
θ value	0.813845 (rank : 28)	NC score	0.031686 (rank : 43)
Query Neighborhood Hits	93	Target Neighborhood Hits	722	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SP5_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.005921 (rank : 91)
Query Neighborhood Hits	93	Target Neighborhood Hits	832	Shared Neighborhood Hits	12
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

ASPP1_MOUSE
θ value	1.06291 (rank : 30)	NC score	0.033473 (rank : 40)
Query Neighborhood Hits	93	Target Neighborhood Hits	1244	Shared Neighborhood Hits	35
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

EGLX_MOUSE
θ value	1.06291 (rank : 31)	NC score	0.036814 (rank : 38)
Query Neighborhood Hits	93	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BG58, Q8CAF1, Q9D499	Gene names	Ph4
Domain Architecture
Description	Putative HIF-prolyl hydroxylase PH-4 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl 4-hydroxylase).

KTN1_HUMAN
θ value	1.06291 (rank : 32)	NC score	0.022006 (rank : 62)
Query Neighborhood Hits	93	Target Neighborhood Hits	1197	Shared Neighborhood Hits	22
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

CIC_MOUSE
θ value	1.38821 (rank : 33)	NC score	0.043955 (rank : 34)
Query Neighborhood Hits	93	Target Neighborhood Hits	742	Shared Neighborhood Hits	24
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CN032_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.067382 (rank : 24)
Query Neighborhood Hits	93	Target Neighborhood Hits	267	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

WBP11_MOUSE
θ value	1.38821 (rank : 35)	NC score	0.053838 (rank : 28)
Query Neighborhood Hits	93	Target Neighborhood Hits	362	Shared Neighborhood Hits	18
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

AMOT_HUMAN
θ value	1.81305 (rank : 36)	NC score	0.033182 (rank : 41)
Query Neighborhood Hits	93	Target Neighborhood Hits	712	Shared Neighborhood Hits	21
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

BSN_HUMAN
θ value	1.81305 (rank : 37)	NC score	0.038472 (rank : 36)
Query Neighborhood Hits	93	Target Neighborhood Hits	1537	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CIC_HUMAN
θ value	1.81305 (rank : 38)	NC score	0.041826 (rank : 35)
Query Neighborhood Hits	93	Target Neighborhood Hits	992	Shared Neighborhood Hits	28
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CSPG3_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.011741 (rank : 81)
Query Neighborhood Hits	93	Target Neighborhood Hits	676	Shared Neighborhood Hits	13
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

MYH1_MOUSE
θ value	1.81305 (rank : 40)	NC score	0.023957 (rank : 53)
Query Neighborhood Hits	93	Target Neighborhood Hits	1461	Shared Neighborhood Hits	20
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH4_MOUSE
θ value	1.81305 (rank : 41)	NC score	0.023706 (rank : 54)
Query Neighborhood Hits	93	Target Neighborhood Hits	1476	Shared Neighborhood Hits	19
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH8_HUMAN
θ value	1.81305 (rank : 42)	NC score	0.024525 (rank : 52)
Query Neighborhood Hits	93	Target Neighborhood Hits	1610	Shared Neighborhood Hits	24
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

ANKZ1_MOUSE
θ value	2.36792 (rank : 43)	NC score	0.034562 (rank : 39)
Query Neighborhood Hits	93	Target Neighborhood Hits	208	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

CO039_MOUSE
θ value	2.36792 (rank : 44)	NC score	0.050974 (rank : 31)
Query Neighborhood Hits	93	Target Neighborhood Hits	445	Shared Neighborhood Hits	22
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

TARA_MOUSE
θ value	2.36792 (rank : 45)	NC score	0.032884 (rank : 42)
Query Neighborhood Hits	93	Target Neighborhood Hits	1133	Shared Neighborhood Hits	26
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

VWF_MOUSE
θ value	2.36792 (rank : 46)	NC score	0.012034 (rank : 79)
Query Neighborhood Hits	93	Target Neighborhood Hits	381	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ANR11_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.027027 (rank : 49)
Query Neighborhood Hits	93	Target Neighborhood Hits	1289	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ATX2_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.030072 (rank : 46)
Query Neighborhood Hits	93	Target Neighborhood Hits	375	Shared Neighborhood Hits	14
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

BACH_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.025951 (rank : 50)
Query Neighborhood Hits	93	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	O00154, O43703, Q5JYL4, Q9UJM9, Q9Y539, Q9Y540	Gene names	ACOT7, BACH
Domain Architecture
Description	Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Long chain acyl-CoA thioester hydrolase) (CTE-II) (CTE-IIa) (Brain acyl-CoA hydrolase) (Acyl-CoA thioesterase 7).

BT3A2_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.013672 (rank : 74)
Query Neighborhood Hits	93	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

CO039_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.052538 (rank : 30)
Query Neighborhood Hits	93	Target Neighborhood Hits	264	Shared Neighborhood Hits	17
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

DDX51_MOUSE
θ value	3.0926 (rank : 52)	NC score	0.009946 (rank : 84)
Query Neighborhood Hits	93	Target Neighborhood Hits	130	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

FA8_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.012746 (rank : 77)
Query Neighborhood Hits	93	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

GP176_MOUSE
θ value	3.0926 (rank : 54)	NC score	0.007444 (rank : 89)
Query Neighborhood Hits	93	Target Neighborhood Hits	539	Shared Neighborhood Hits	5
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

KTN1_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.019549 (rank : 66)
Query Neighborhood Hits	93	Target Neighborhood Hits	1324	Shared Neighborhood Hits	19
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MYH4_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.023599 (rank : 55)
Query Neighborhood Hits	93	Target Neighborhood Hits	1377	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

NELFA_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.031118 (rank : 45)
Query Neighborhood Hits	93	Target Neighborhood Hits	195	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

NRG3_MOUSE
θ value	3.0926 (rank : 58)	NC score	0.031274 (rank : 44)
Query Neighborhood Hits	93	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

SMRCD_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.009913 (rank : 85)
Query Neighborhood Hits	93	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

WNK2_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.008249 (rank : 87)
Query Neighborhood Hits	93	Target Neighborhood Hits	1407	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

K0773_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.023082 (rank : 56)
Query Neighborhood Hits	93	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q86XD5, Q7L0D6, Q86T97	Gene names	KIAA0773
Domain Architecture	No domain graphic available
Description	Uncharacterized protein KIAA0773.

MAGE1_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.028481 (rank : 48)
Query Neighborhood Hits	93	Target Neighborhood Hits	1389	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MYH2_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.023039 (rank : 57)
Query Neighborhood Hits	93	Target Neighborhood Hits	1491	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

STAR7_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.028686 (rank : 47)
Query Neighborhood Hits	93	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQZ5, Q6GU43, Q969M6	Gene names	STARD7
Domain Architecture
Description	StAR-related lipid transfer protein 7 (StARD7) (START domain- containing protein 7) (Protein GTT1).

WBP11_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.047266 (rank : 33)
Query Neighborhood Hits	93	Target Neighborhood Hits	354	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

HDAC7_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.011038 (rank : 82)
Query Neighborhood Hits	93	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C2B3, Q8C2C9, Q8C8X4, Q8CB80, Q8CDA3, Q9JL72	Gene names	Hdac7a, Hdac7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

HSF2_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.019695 (rank : 65)
Query Neighborhood Hits	93	Target Neighborhood Hits	149	Shared Neighborhood Hits	11
SwissProt Accessions	Q03933, Q9H445	Gene names	HSF2, HSTF2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

MISS_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.056935 (rank : 27)
Query Neighborhood Hits	93	Target Neighborhood Hits	444	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MYH1_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.022409 (rank : 61)
Query Neighborhood Hits	93	Target Neighborhood Hits	1478	Shared Neighborhood Hits	19
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

SL9A3_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.012349 (rank : 78)
Query Neighborhood Hits	93	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	P48764	Gene names	SLC9A3, NHE3
Domain Architecture
Description	Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3).

SYP2L_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.022948 (rank : 58)
Query Neighborhood Hits	93	Target Neighborhood Hits	400	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TULP4_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.017815 (rank : 67)
Query Neighborhood Hits	93	Target Neighborhood Hits	426	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

CBL_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.014220 (rank : 73)
Query Neighborhood Hits	93	Target Neighborhood Hits	353	Shared Neighborhood Hits	13
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CDYL2_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.010452 (rank : 83)
Query Neighborhood Hits	93	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N8U2	Gene names	CDYL2
Domain Architecture
Description	Chromodomain Y-like protein 2 (CDY-like 2).

FMNL_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.019899 (rank : 64)
Query Neighborhood Hits	93	Target Neighborhood Hits	428	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

FOXN1_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.009137 (rank : 86)
Query Neighborhood Hits	93	Target Neighborhood Hits	300	Shared Neighborhood Hits	12
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

GBP2_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.012019 (rank : 80)
Query Neighborhood Hits	93	Target Neighborhood Hits	349	Shared Neighborhood Hits	11
SwissProt Accessions	P32456, Q86TB0	Gene names	GBP2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (HuGBP-2).

GP152_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.007144 (rank : 90)
Query Neighborhood Hits	93	Target Neighborhood Hits	607	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

SP5_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.003540 (rank : 93)
Query Neighborhood Hits	93	Target Neighborhood Hits	821	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JHX2	Gene names	Sp5
Domain Architecture
Description	Transcription factor Sp5.

CAC2D_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.069817 (rank : 22)
Query Neighborhood Hits	93	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	P54289	Gene names	CACNA2D1, CACNL2A, CCHL2A
Domain Architecture
Description	Dihydropyridine-sensitive L-type calcium channel subunits alpha- 2/delta precursor [Contains: L-type calcium channel subunit alpha-2; L-type calcium channel subunit delta].

CAC2D_MOUSE
θ value	8.99809 (rank : 81)	NC score	0.069384 (rank : 23)
Query Neighborhood Hits	93	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	O08532, O08533, O08534, O08535, O08536	Gene names	Cacna2d1, Cacna2
Domain Architecture
Description	Dihydropyridine-sensitive L-type calcium channel subunits alpha- 2/delta precursor [Contains: L-type calcium channel subunit alpha-2; L-type calcium channel subunit delta].

FKSG2_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.014233 (rank : 72)
Query Neighborhood Hits	93	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAU6	Gene names	FKSG2
Domain Architecture
Description	Apoptosis inhibitor FKSG2.

IF35_MOUSE
θ value	8.99809 (rank : 83)	NC score	0.022681 (rank : 60)
Query Neighborhood Hits	93	Target Neighborhood Hits	210	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

IQEC2_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.014960 (rank : 70)
Query Neighborhood Hits	93	Target Neighborhood Hits	403	Shared Neighborhood Hits	13
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.014892 (rank : 71)
Query Neighborhood Hits	93	Target Neighborhood Hits	417	Shared Neighborhood Hits	13
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

K0100_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.017532 (rank : 69)
Query Neighborhood Hits	93	Target Neighborhood Hits	132	Shared Neighborhood Hits	5
SwissProt Accessions	Q14667, Q3SYN5, Q49A07, Q5H9T4, Q6WG74, Q6ZP51, Q96HH8	Gene names	KIAA0100, BCOX1
Domain Architecture	No domain graphic available
Description	UPF0378 family protein KIAA0100 precursor (Breast cancer overexpressed gene 1 protein) (Antigen MLAA-22).

K0100_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.017805 (rank : 68)
Query Neighborhood Hits	93	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SYL3, Q3UE65, Q66JY1, Q6DIC4, Q80U77, Q8C1W6, Q8CE06, Q8CGE3, Q9CSS8	Gene names	Kiaa0100
Domain Architecture	No domain graphic available
Description	UPF0378 family protein KIAA0100 precursor.

MYO9B_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.020000 (rank : 63)
Query Neighborhood Hits	93	Target Neighborhood Hits	641	Shared Neighborhood Hits	20
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RNPC1_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.007798 (rank : 88)
Query Neighborhood Hits	93	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	Q62176, Q922Z2	Gene names	Rnpc1, Seb4, Seb4l
Domain Architecture
Description	RNA-binding region-containing protein 1 (ssDNA-binding protein SEB4).

STAR7_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.022773 (rank : 59)
Query Neighborhood Hits	93	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1R3	Gene names	Stard7
Domain Architecture
Description	StAR-related lipid transfer protein 7 (StARD7) (START domain- containing protein 7).

SYCP1_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.013102 (rank : 75)
Query Neighborhood Hits	93	Target Neighborhood Hits	1313	Shared Neighborhood Hits	20
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TAF5L_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.001983 (rank : 94)
Query Neighborhood Hits	93	Target Neighborhood Hits	330	Shared Neighborhood Hits	3
SwissProt Accessions	O75529, Q8IW31	Gene names	TAF5L, PAF65B
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).

THAP4_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.012802 (rank : 76)
Query Neighborhood Hits	93	Target Neighborhood Hits	130	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

RPC1_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.052941 (rank : 29)
Query Neighborhood Hits	93	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O14802, Q8TCW5	Gene names	POLR3A
Domain Architecture
Description	DNA-directed RNA polymerase III largest subunit (EC 2.7.7.6) (RPC155) (RPC1).

Hits sorted by NC score

PARP4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	93	Target Neighborhood Hits	93	Shared Neighborhood Hits	93
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

LHR2A_MOUSE
NC score	0.641603 (rank : 2)	θ value	3.85808e-43 (rank : 2)
Query Neighborhood Hits	93	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q99KC8, Q3TTU2, Q6UN22, Q8BHA8, Q9CTV9	Gene names	Loh11cr2a
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog.

LHR2A_HUMAN
NC score	0.630753 (rank : 3)	θ value	5.76516e-39 (rank : 3)
Query Neighborhood Hits	93	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	O00534, Q6UN19, Q6UN20, Q9BVF8	Gene names	LOH11CR2A, BCSC1
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein (Breast cancer suppressor candidate 1) (BCSC-1).

PARP2_HUMAN
NC score	0.566220 (rank : 4)	θ value	3.75424e-22 (rank : 6)
Query Neighborhood Hits	93	Target Neighborhood Hits	33	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

PARP1_HUMAN
NC score	0.557600 (rank : 5)	θ value	3.07116e-24 (rank : 4)
Query Neighborhood Hits	93	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

PARP2_MOUSE
NC score	0.551828 (rank : 6)	θ value	5.07402e-19 (rank : 7)
Query Neighborhood Hits	93	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

PARP1_MOUSE
NC score	0.548923 (rank : 7)	θ value	4.43474e-23 (rank : 5)
Query Neighborhood Hits	93	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

PARP3_HUMAN
NC score	0.538458 (rank : 8)	θ value	1.09485e-13 (rank : 8)
Query Neighborhood Hits	93	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

ITIH4_HUMAN
NC score	0.344964 (rank : 9)	θ value	5.08577e-11 (rank : 9)
Query Neighborhood Hits	93	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	Q14624, Q15135, Q9P190, Q9UQ54	Gene names	ITIH4, IHRP, ITIHL1, PK120
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H4 precursor (ITI heavy chain H4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (PK-120) (GP120) [Contains: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha- trypsin inhibitor heavy chain H4].

ITIH3_HUMAN
NC score	0.287804 (rank : 10)	θ value	2.21117e-06 (rank : 10)
Query Neighborhood Hits	93	Target Neighborhood Hits	38	Shared Neighborhood Hits	12
SwissProt Accessions	Q06033, Q99085	Gene names	ITIH3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3) (Serum-derived hyaluronan-associated protein) (SHAP).

ITIH1_HUMAN
NC score	0.286447 (rank : 11)	θ value	0.000602161 (rank : 15)
Query Neighborhood Hits	93	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P19827, P78455, Q01746	Gene names	ITIH1, IGHEP1
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H1 precursor (ITI heavy chain H1) (Inter-alpha-inhibitor heavy chain 1) (Inter-alpha-trypsin inhibitor complex component III) (Serum-derived hyaluronan-associated protein) (SHAP).

ITIH3_MOUSE
NC score	0.280170 (rank : 12)	θ value	2.44474e-05 (rank : 11)
Query Neighborhood Hits	93	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q61704	Gene names	Itih3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3).

ITIH1_MOUSE
NC score	0.275438 (rank : 13)	θ value	0.000270298 (rank : 14)
Query Neighborhood Hits	93	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	Q61702	Gene names	Itih1
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H1 precursor (ITI heavy chain H1) (Inter-alpha-inhibitor heavy chain 1).

ITIH2_MOUSE
NC score	0.247242 (rank : 14)	θ value	0.00175202 (rank : 19)
Query Neighborhood Hits	93	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	Q61703	Gene names	Itih2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2).

ITIH2_HUMAN
NC score	0.227211 (rank : 15)	θ value	0.0431538 (rank : 23)
Query Neighborhood Hits	93	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	P19823, Q14659, Q15484	Gene names	ITIH2, IGHEP2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2) (Inter-alpha-trypsin inhibitor complex component II) (Serum-derived hyaluronan-associated protein) (SHAP).

RPB1_HUMAN
NC score	0.106440 (rank : 16)	θ value	0.00134147 (rank : 17)
Query Neighborhood Hits	93	Target Neighborhood Hits	362	Shared Neighborhood Hits	11
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
NC score	0.106422 (rank : 17)	θ value	0.00134147 (rank : 18)
Query Neighborhood Hits	93	Target Neighborhood Hits	363	Shared Neighborhood Hits	11
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

CCDC4_HUMAN
NC score	0.102755 (rank : 18)	θ value	0.0431538 (rank : 21)
Query Neighborhood Hits	93	Target Neighborhood Hits	104	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZU67, Q58A26, Q58A27	Gene names	CCDC4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 4.

CN032_MOUSE
NC score	0.098698 (rank : 19)	θ value	0.0431538 (rank : 22)
Query Neighborhood Hits	93	Target Neighborhood Hits	233	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

TNKS1_HUMAN
NC score	0.081017 (rank : 20)	θ value	5.44631e-05 (rank : 13)
Query Neighborhood Hits	93	Target Neighborhood Hits	477	Shared Neighborhood Hits	19
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

TNKS2_HUMAN
NC score	0.076273 (rank : 21)	θ value	3.19293e-05 (rank : 12)
Query Neighborhood Hits	93	Target Neighborhood Hits	361	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

CAC2D_HUMAN
NC score	0.069817 (rank : 22)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	93	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	P54289	Gene names	CACNA2D1, CACNL2A, CCHL2A
Domain Architecture
Description	Dihydropyridine-sensitive L-type calcium channel subunits alpha- 2/delta precursor [Contains: L-type calcium channel subunit alpha-2; L-type calcium channel subunit delta].

CAC2D_MOUSE
NC score	0.069384 (rank : 23)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	93	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	O08532, O08533, O08534, O08535, O08536	Gene names	Cacna2d1, Cacna2
Domain Architecture
Description	Dihydropyridine-sensitive L-type calcium channel subunits alpha- 2/delta precursor [Contains: L-type calcium channel subunit alpha-2; L-type calcium channel subunit delta].

CN032_HUMAN
NC score	0.067382 (rank : 24)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	93	Target Neighborhood Hits	267	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

ZCC2_HUMAN
NC score	0.062668 (rank : 25)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	93	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z2W4, Q8IW57, Q8TAJ3, Q96N79, Q9H8R9, Q9P0Y7	Gene names	ZC3HAV1, ZC3HDC2
Domain Architecture
Description	Zinc finger CCCH type antiviral protein 1 (Zinc finger CCCH domain- containing protein 2).

MUC1_HUMAN
NC score	0.059614 (rank : 26)	θ value	0.00134147 (rank : 16)
Query Neighborhood Hits	93	Target Neighborhood Hits	975	Shared Neighborhood Hits	34
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MISS_MOUSE
NC score	0.056935 (rank : 27)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	93	Target Neighborhood Hits	444	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

WBP11_MOUSE
NC score	0.053838 (rank : 28)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	93	Target Neighborhood Hits	362	Shared Neighborhood Hits	18
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

RPC1_HUMAN
NC score	0.052941 (rank : 29)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	93	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O14802, Q8TCW5	Gene names	POLR3A
Domain Architecture
Description	DNA-directed RNA polymerase III largest subunit (EC 2.7.7.6) (RPC155) (RPC1).

CO039_HUMAN
NC score	0.052538 (rank : 30)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	93	Target Neighborhood Hits	264	Shared Neighborhood Hits	17
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CO039_MOUSE
NC score	0.050974 (rank : 31)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	93	Target Neighborhood Hits	445	Shared Neighborhood Hits	22
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

NACAM_MOUSE
NC score	0.048274 (rank : 32)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	93	Target Neighborhood Hits	1866	Shared Neighborhood Hits	41
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

WBP11_HUMAN
NC score	0.047266 (rank : 33)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	93	Target Neighborhood Hits	354	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

CIC_MOUSE
NC score	0.043955 (rank : 34)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	93	Target Neighborhood Hits	742	Shared Neighborhood Hits	24
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_HUMAN
NC score	0.041826 (rank : 35)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	93	Target Neighborhood Hits	992	Shared Neighborhood Hits	28
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

BSN_HUMAN
NC score	0.038472 (rank : 36)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	93	Target Neighborhood Hits	1537	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

TSH1_HUMAN
NC score	0.038140 (rank : 37)	θ value	0.0330416 (rank : 20)
Query Neighborhood Hits	93	Target Neighborhood Hits	558	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

EGLX_MOUSE
NC score	0.036814 (rank : 38)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	93	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BG58, Q8CAF1, Q9D499	Gene names	Ph4
Domain Architecture
Description	Putative HIF-prolyl hydroxylase PH-4 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl 4-hydroxylase).

ANKZ1_MOUSE
NC score	0.034562 (rank : 39)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	93	Target Neighborhood Hits	208	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

ASPP1_MOUSE
NC score	0.033473 (rank : 40)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	93	Target Neighborhood Hits	1244	Shared Neighborhood Hits	35
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

AMOT_HUMAN
NC score	0.033182 (rank : 41)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	93	Target Neighborhood Hits	712	Shared Neighborhood Hits	21
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

TARA_MOUSE
NC score	0.032884 (rank : 42)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	93	Target Neighborhood Hits	1133	Shared Neighborhood Hits	26
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MLL4_HUMAN
NC score	0.031686 (rank : 43)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	93	Target Neighborhood Hits	722	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

NRG3_MOUSE
NC score	0.031274 (rank : 44)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	93	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NELFA_MOUSE
NC score	0.031118 (rank : 45)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	93	Target Neighborhood Hits	195	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

ATX2_HUMAN
NC score	0.030072 (rank : 46)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	93	Target Neighborhood Hits	375	Shared Neighborhood Hits	14
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

STAR7_HUMAN
NC score	0.028686 (rank : 47)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	93	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQZ5, Q6GU43, Q969M6	Gene names	STARD7
Domain Architecture
Description	StAR-related lipid transfer protein 7 (StARD7) (START domain- containing protein 7) (Protein GTT1).

MAGE1_HUMAN
NC score	0.028481 (rank : 48)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	93	Target Neighborhood Hits	1389	Shared Neighborhood Hits	40
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ANR11_HUMAN
NC score	0.027027 (rank : 49)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	93	Target Neighborhood Hits	1289	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

BACH_HUMAN
NC score	0.025951 (rank : 50)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	93	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	O00154, O43703, Q5JYL4, Q9UJM9, Q9Y539, Q9Y540	Gene names	ACOT7, BACH
Domain Architecture
Description	Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Long chain acyl-CoA thioester hydrolase) (CTE-II) (CTE-IIa) (Brain acyl-CoA hydrolase) (Acyl-CoA thioesterase 7).

MYH8_MOUSE
NC score	0.025725 (rank : 51)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	93	Target Neighborhood Hits	1600	Shared Neighborhood Hits	20
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH8_HUMAN
NC score	0.024525 (rank : 52)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	93	Target Neighborhood Hits	1610	Shared Neighborhood Hits	24
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH1_MOUSE
NC score	0.023957 (rank : 53)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	93	Target Neighborhood Hits	1461	Shared Neighborhood Hits	20
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH4_MOUSE
NC score	0.023706 (rank : 54)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	93	Target Neighborhood Hits	1476	Shared Neighborhood Hits	19
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH4_HUMAN
NC score	0.023599 (rank : 55)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	93	Target Neighborhood Hits	1377	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

K0773_HUMAN
NC score	0.023082 (rank : 56)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	93	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q86XD5, Q7L0D6, Q86T97	Gene names	KIAA0773
Domain Architecture	No domain graphic available
Description	Uncharacterized protein KIAA0773.

MYH2_HUMAN
NC score	0.023039 (rank : 57)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	93	Target Neighborhood Hits	1491	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

SYP2L_HUMAN
NC score	0.022948 (rank : 58)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	93	Target Neighborhood Hits	400	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

STAR7_MOUSE
NC score	0.022773 (rank : 59)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	93	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1R3	Gene names	Stard7
Domain Architecture
Description	StAR-related lipid transfer protein 7 (StARD7) (START domain- containing protein 7).

IF35_MOUSE
NC score	0.022681 (rank : 60)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	93	Target Neighborhood Hits	210	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DCH4	Gene names	Eif3s5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

MYH1_HUMAN
NC score	0.022409 (rank : 61)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	93	Target Neighborhood Hits	1478	Shared Neighborhood Hits	19
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

KTN1_HUMAN
NC score	0.022006 (rank : 62)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	93	Target Neighborhood Hits	1197	Shared Neighborhood Hits	22
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

MYO9B_HUMAN
NC score	0.020000 (rank : 63)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	93	Target Neighborhood Hits	641	Shared Neighborhood Hits	20
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

FMNL_MOUSE
NC score	0.019899 (rank : 64)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	93	Target Neighborhood Hits	428	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

HSF2_HUMAN
NC score	0.019695 (rank : 65)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	93	Target Neighborhood Hits	149	Shared Neighborhood Hits	11
SwissProt Accessions	Q03933, Q9H445	Gene names	HSF2, HSTF2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

KTN1_MOUSE
NC score	0.019549 (rank : 66)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	93	Target Neighborhood Hits	1324	Shared Neighborhood Hits	19
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

TULP4_HUMAN
NC score	0.017815 (rank : 67)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	93	Target Neighborhood Hits	426	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

K0100_MOUSE
NC score	0.017805 (rank : 68)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	93	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SYL3, Q3UE65, Q66JY1, Q6DIC4, Q80U77, Q8C1W6, Q8CE06, Q8CGE3, Q9CSS8	Gene names	Kiaa0100
Domain Architecture	No domain graphic available
Description	UPF0378 family protein KIAA0100 precursor.

K0100_HUMAN
NC score	0.017532 (rank : 69)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	93	Target Neighborhood Hits	132	Shared Neighborhood Hits	5
SwissProt Accessions	Q14667, Q3SYN5, Q49A07, Q5H9T4, Q6WG74, Q6ZP51, Q96HH8	Gene names	KIAA0100, BCOX1
Domain Architecture	No domain graphic available
Description	UPF0378 family protein KIAA0100 precursor (Breast cancer overexpressed gene 1 protein) (Antigen MLAA-22).

IQEC2_HUMAN
NC score	0.014960 (rank : 70)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	93	Target Neighborhood Hits	403	Shared Neighborhood Hits	13
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
NC score	0.014892 (rank : 71)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	93	Target Neighborhood Hits	417	Shared Neighborhood Hits	13
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

FKSG2_HUMAN
NC score	0.014233 (rank : 72)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	93	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAU6	Gene names	FKSG2
Domain Architecture
Description	Apoptosis inhibitor FKSG2.

CBL_HUMAN
NC score	0.014220 (rank : 73)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	93	Target Neighborhood Hits	353	Shared Neighborhood Hits	13
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

BT3A2_HUMAN
NC score	0.013672 (rank : 74)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	93	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

SYCP1_HUMAN
NC score	0.013102 (rank : 75)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	93	Target Neighborhood Hits	1313	Shared Neighborhood Hits	20
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

THAP4_MOUSE
NC score	0.012802 (rank : 76)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	93	Target Neighborhood Hits	130	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

FA8_HUMAN
NC score	0.012746 (rank : 77)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	93	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

SL9A3_HUMAN
NC score	0.012349 (rank : 78)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	93	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	P48764	Gene names	SLC9A3, NHE3
Domain Architecture
Description	Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3).

VWF_MOUSE
NC score	0.012034 (rank : 79)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	93	Target Neighborhood Hits	381	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

GBP2_HUMAN
NC score	0.012019 (rank : 80)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	93	Target Neighborhood Hits	349	Shared Neighborhood Hits	11
SwissProt Accessions	P32456, Q86TB0	Gene names	GBP2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (HuGBP-2).

CSPG3_HUMAN
NC score	0.011741 (rank : 81)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	93	Target Neighborhood Hits	676	Shared Neighborhood Hits	13
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

HDAC7_MOUSE
NC score	0.011038 (rank : 82)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	93	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C2B3, Q8C2C9, Q8C8X4, Q8CB80, Q8CDA3, Q9JL72	Gene names	Hdac7a, Hdac7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

CDYL2_HUMAN
NC score	0.010452 (rank : 83)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	93	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N8U2	Gene names	CDYL2
Domain Architecture
Description	Chromodomain Y-like protein 2 (CDY-like 2).

DDX51_MOUSE
NC score	0.009946 (rank : 84)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	93	Target Neighborhood Hits	130	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

SMRCD_HUMAN
NC score	0.009913 (rank : 85)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	93	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

FOXN1_MOUSE
NC score	0.009137 (rank : 86)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	93	Target Neighborhood Hits	300	Shared Neighborhood Hits	12
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

WNK2_HUMAN
NC score	0.008249 (rank : 87)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	93	Target Neighborhood Hits	1407	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

RNPC1_MOUSE
NC score	0.007798 (rank : 88)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	93	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	Q62176, Q922Z2	Gene names	Rnpc1, Seb4, Seb4l
Domain Architecture
Description	RNA-binding region-containing protein 1 (ssDNA-binding protein SEB4).

GP176_MOUSE
NC score	0.007444 (rank : 89)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	93	Target Neighborhood Hits	539	Shared Neighborhood Hits	5
SwissProt Accessions	Q80WT4, Q80UC4	Gene names	Gpr176, Agr9, Gm1012
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 176 (G-protein coupled receptor AGR9).

GP152_MOUSE
NC score	0.007144 (rank : 90)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	93	Target Neighborhood Hits	607	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

SP5_HUMAN
NC score	0.005921 (rank : 91)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	93	Target Neighborhood Hits	832	Shared Neighborhood Hits	12
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

M3K6_HUMAN
NC score	0.003583 (rank : 92)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	93	Target Neighborhood Hits	889	Shared Neighborhood Hits	5
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

SP5_MOUSE
NC score	0.003540 (rank : 93)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	93	Target Neighborhood Hits	821	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JHX2	Gene names	Sp5
Domain Architecture
Description	Transcription factor Sp5.

TAF5L_HUMAN
NC score	0.001983 (rank : 94)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	93	Target Neighborhood Hits	330	Shared Neighborhood Hits	3
SwissProt Accessions	O75529, Q8IW31	Gene names	TAF5L, PAF65B
Domain Architecture
Description	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65- beta).