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Network neighborhood for query Sequence : ITIH3_HUMAN

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ITIH3_HUMAN
SwissProt Accessions	Q06033, Q99085	Gene names	ITIH3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3) (Serum-derived hyaluronan-associated protein) (SHAP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ITIH1_HUMAN
θ value	0 (rank : 1)	NC score	0.986979 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P19827, P78455, Q01746	Gene names	ITIH1, IGHEP1
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H1 precursor (ITI heavy chain H1) (Inter-alpha-inhibitor heavy chain 1) (Inter-alpha-trypsin inhibitor complex component III) (Serum-derived hyaluronan-associated protein) (SHAP).

ITIH1_MOUSE
θ value	0 (rank : 2)	NC score	0.987534 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q61702	Gene names	Itih1
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H1 precursor (ITI heavy chain H1) (Inter-alpha-inhibitor heavy chain 1).

ITIH2_HUMAN
θ value	0 (rank : 3)	NC score	0.971754 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	P19823, Q14659, Q15484	Gene names	ITIH2, IGHEP2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2) (Inter-alpha-trypsin inhibitor complex component II) (Serum-derived hyaluronan-associated protein) (SHAP).

ITIH2_MOUSE
θ value	0 (rank : 4)	NC score	0.970738 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	Q61703	Gene names	Itih2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2).

ITIH3_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q06033, Q99085	Gene names	ITIH3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3) (Serum-derived hyaluronan-associated protein) (SHAP).

ITIH3_MOUSE
θ value	0 (rank : 6)	NC score	0.996901 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q61704	Gene names	Itih3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3).

ITIH4_HUMAN
θ value	1.36511e-173 (rank : 7)	NC score	0.971576 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	Q14624, Q15135, Q9P190, Q9UQ54	Gene names	ITIH4, IHRP, ITIHL1, PK120
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H4 precursor (ITI heavy chain H4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (PK-120) (GP120) [Contains: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha- trypsin inhibitor heavy chain H4].

CAC2D_HUMAN
θ value	4.76016e-09 (rank : 8)	NC score	0.349666 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	P54289	Gene names	CACNA2D1, CACNL2A, CCHL2A
Domain Architecture
Description	Dihydropyridine-sensitive L-type calcium channel subunits alpha- 2/delta precursor [Contains: L-type calcium channel subunit alpha-2; L-type calcium channel subunit delta].

CAC2D_MOUSE
θ value	4.76016e-09 (rank : 9)	NC score	0.350310 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	O08532, O08533, O08534, O08535, O08536	Gene names	Cacna2d1, Cacna2
Domain Architecture
Description	Dihydropyridine-sensitive L-type calcium channel subunits alpha- 2/delta precursor [Contains: L-type calcium channel subunit alpha-2; L-type calcium channel subunit delta].

PARP4_HUMAN
θ value	2.21117e-06 (rank : 10)	NC score	0.287804 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	93	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

LHR2A_HUMAN
θ value	1.87187e-05 (rank : 11)	NC score	0.306928 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	O00534, Q6UN19, Q6UN20, Q9BVF8	Gene names	LOH11CR2A, BCSC1
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein (Breast cancer suppressor candidate 1) (BCSC-1).

LHR2A_MOUSE
θ value	0.000602161 (rank : 12)	NC score	0.279594 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	Q99KC8, Q3TTU2, Q6UN22, Q8BHA8, Q9CTV9	Gene names	Loh11cr2a
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog.

ITAM_HUMAN
θ value	0.21417 (rank : 13)	NC score	0.020161 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	P11215	Gene names	ITGAM, CD11B, CR3A
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD11b antigen).

TENX_HUMAN
θ value	0.813845 (rank : 14)	NC score	0.005278 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	789	Shared Neighborhood Hits	3
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

ZN746_MOUSE
θ value	1.06291 (rank : 15)	NC score	0.002946 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	748	Shared Neighborhood Hits	5
SwissProt Accessions	Q3U133	Gene names	Znf746, Zfp746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

INP4B_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.016673 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P1Y8	Gene names	Inpp4b
Domain Architecture	No domain graphic available
Description	Type II inositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type II).

GALA_MOUSE
θ value	2.36792 (rank : 17)	NC score	0.028839 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P47212	Gene names	Gal, Galn
Domain Architecture
Description	Galanin precursor [Contains: Galanin; Galanin message-associated peptide (GMAP)].

KPCD_HUMAN
θ value	2.36792 (rank : 18)	NC score	0.000559 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	900	Shared Neighborhood Hits	4
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

BPA1_MOUSE
θ value	3.0926 (rank : 19)	NC score	0.002791 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	1477	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CO6A2_MOUSE
θ value	3.0926 (rank : 20)	NC score	0.007037 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	260	Shared Neighborhood Hits	4
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

DIAP1_MOUSE
θ value	3.0926 (rank : 21)	NC score	0.005970 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	839	Shared Neighborhood Hits	5
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

ITAM_MOUSE
θ value	4.03905 (rank : 22)	NC score	0.020996 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	77	Shared Neighborhood Hits	9
SwissProt Accessions	P05555, Q8CA73	Gene names	Itgam
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (CD11b antigen).

NSD1_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.014268 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	472	Shared Neighborhood Hits	5
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

VIGLN_MOUSE
θ value	4.03905 (rank : 24)	NC score	0.012133 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

ANKS6_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.008708 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	411	Shared Neighborhood Hits	4
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

CCD41_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.001741 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	1139	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

NSF1C_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.017468 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNZ2, Q7Z533, Q9H102, Q9NVL9, Q9UI06	Gene names	NSFL1C
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

NSF1C_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.017514 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZ44, Q80Y15, Q8BYL3	Gene names	Nsfl1c
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

PGFRA_HUMAN
θ value	5.27518 (rank : 29)	NC score	-0.000052 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	980	Shared Neighborhood Hits	3
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

I2C1_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.007040 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UL18, Q5TA57, Q6P4S0	Gene names	EIF2C1, AGO1
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 1 (eIF2C 1) (eIF-2C 1) (Argonaute-1) (Putative RNA-binding protein Q99).

I2C1_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.007059 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CJG1	Gene names	Eif2c1, Ago1
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 1 (eIF2C 1) (eIF-2C 1) (Argonaute-1) (Piwi/argonaute family protein meIF2C1).

KIF14_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.002111 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	732	Shared Neighborhood Hits	5
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

UBE3A_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.004421 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

ZN746_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.000860 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	745	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NUN9	Gene names	ZNF746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

ABCF1_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.004152 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	321	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

ANKS6_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.007097 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	435	Shared Neighborhood Hits	5
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

CCD38_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.005580 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	287	Shared Neighborhood Hits	2
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

CO2_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.007705 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	250	Shared Neighborhood Hits	3
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

Hits sorted by NC score

ITIH3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	38	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q06033, Q99085	Gene names	ITIH3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3) (Serum-derived hyaluronan-associated protein) (SHAP).

ITIH3_MOUSE
NC score	0.996901 (rank : 2)	θ value	0 (rank : 6)
Query Neighborhood Hits	38	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q61704	Gene names	Itih3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3).

ITIH1_MOUSE
NC score	0.987534 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	38	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q61702	Gene names	Itih1
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H1 precursor (ITI heavy chain H1) (Inter-alpha-inhibitor heavy chain 1).

ITIH1_HUMAN
NC score	0.986979 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	38	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P19827, P78455, Q01746	Gene names	ITIH1, IGHEP1
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H1 precursor (ITI heavy chain H1) (Inter-alpha-inhibitor heavy chain 1) (Inter-alpha-trypsin inhibitor complex component III) (Serum-derived hyaluronan-associated protein) (SHAP).

ITIH2_HUMAN
NC score	0.971754 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	38	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	P19823, Q14659, Q15484	Gene names	ITIH2, IGHEP2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2) (Inter-alpha-trypsin inhibitor complex component II) (Serum-derived hyaluronan-associated protein) (SHAP).

ITIH4_HUMAN
NC score	0.971576 (rank : 6)	θ value	1.36511e-173 (rank : 7)
Query Neighborhood Hits	38	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	Q14624, Q15135, Q9P190, Q9UQ54	Gene names	ITIH4, IHRP, ITIHL1, PK120
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H4 precursor (ITI heavy chain H4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (PK-120) (GP120) [Contains: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha- trypsin inhibitor heavy chain H4].

ITIH2_MOUSE
NC score	0.970738 (rank : 7)	θ value	0 (rank : 4)
Query Neighborhood Hits	38	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	Q61703	Gene names	Itih2
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2).

CAC2D_MOUSE
NC score	0.350310 (rank : 8)	θ value	4.76016e-09 (rank : 9)
Query Neighborhood Hits	38	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	O08532, O08533, O08534, O08535, O08536	Gene names	Cacna2d1, Cacna2
Domain Architecture
Description	Dihydropyridine-sensitive L-type calcium channel subunits alpha- 2/delta precursor [Contains: L-type calcium channel subunit alpha-2; L-type calcium channel subunit delta].

CAC2D_HUMAN
NC score	0.349666 (rank : 9)	θ value	4.76016e-09 (rank : 8)
Query Neighborhood Hits	38	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	P54289	Gene names	CACNA2D1, CACNL2A, CCHL2A
Domain Architecture
Description	Dihydropyridine-sensitive L-type calcium channel subunits alpha- 2/delta precursor [Contains: L-type calcium channel subunit alpha-2; L-type calcium channel subunit delta].

LHR2A_HUMAN
NC score	0.306928 (rank : 10)	θ value	1.87187e-05 (rank : 11)
Query Neighborhood Hits	38	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	O00534, Q6UN19, Q6UN20, Q9BVF8	Gene names	LOH11CR2A, BCSC1
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein (Breast cancer suppressor candidate 1) (BCSC-1).

PARP4_HUMAN
NC score	0.287804 (rank : 11)	θ value	2.21117e-06 (rank : 10)
Query Neighborhood Hits	38	Target Neighborhood Hits	93	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

LHR2A_MOUSE
NC score	0.279594 (rank : 12)	θ value	0.000602161 (rank : 12)
Query Neighborhood Hits	38	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	Q99KC8, Q3TTU2, Q6UN22, Q8BHA8, Q9CTV9	Gene names	Loh11cr2a
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog.

GALA_MOUSE
NC score	0.028839 (rank : 13)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	38	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P47212	Gene names	Gal, Galn
Domain Architecture
Description	Galanin precursor [Contains: Galanin; Galanin message-associated peptide (GMAP)].

ITAM_MOUSE
NC score	0.020996 (rank : 14)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	38	Target Neighborhood Hits	77	Shared Neighborhood Hits	9
SwissProt Accessions	P05555, Q8CA73	Gene names	Itgam
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (CD11b antigen).

ITAM_HUMAN
NC score	0.020161 (rank : 15)	θ value	0.21417 (rank : 13)
Query Neighborhood Hits	38	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	P11215	Gene names	ITGAM, CD11B, CR3A
Domain Architecture
Description	Integrin alpha-M precursor (Cell surface glycoprotein MAC-1 alpha subunit) (CR-3 alpha chain) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD11b antigen).

NSF1C_MOUSE
NC score	0.017514 (rank : 16)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	38	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZ44, Q80Y15, Q8BYL3	Gene names	Nsfl1c
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

NSF1C_HUMAN
NC score	0.017468 (rank : 17)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	38	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNZ2, Q7Z533, Q9H102, Q9NVL9, Q9UI06	Gene names	NSFL1C
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

INP4B_MOUSE
NC score	0.016673 (rank : 18)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	38	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P1Y8	Gene names	Inpp4b
Domain Architecture	No domain graphic available
Description	Type II inositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type II).

NSD1_MOUSE
NC score	0.014268 (rank : 19)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	38	Target Neighborhood Hits	472	Shared Neighborhood Hits	5
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

VIGLN_MOUSE
NC score	0.012133 (rank : 20)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	38	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

ANKS6_HUMAN
NC score	0.008708 (rank : 21)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	38	Target Neighborhood Hits	411	Shared Neighborhood Hits	4
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

CO2_MOUSE
NC score	0.007705 (rank : 22)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	38	Target Neighborhood Hits	250	Shared Neighborhood Hits	3
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

ANKS6_MOUSE
NC score	0.007097 (rank : 23)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	38	Target Neighborhood Hits	435	Shared Neighborhood Hits	5
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

I2C1_MOUSE
NC score	0.007059 (rank : 24)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	38	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CJG1	Gene names	Eif2c1, Ago1
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 1 (eIF2C 1) (eIF-2C 1) (Argonaute-1) (Piwi/argonaute family protein meIF2C1).

I2C1_HUMAN
NC score	0.007040 (rank : 25)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	38	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UL18, Q5TA57, Q6P4S0	Gene names	EIF2C1, AGO1
Domain Architecture
Description	Eukaryotic translation initiation factor 2C 1 (eIF2C 1) (eIF-2C 1) (Argonaute-1) (Putative RNA-binding protein Q99).

CO6A2_MOUSE
NC score	0.007037 (rank : 26)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	38	Target Neighborhood Hits	260	Shared Neighborhood Hits	4
SwissProt Accessions	Q02788, Q05505	Gene names	Col6a2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

DIAP1_MOUSE
NC score	0.005970 (rank : 27)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	38	Target Neighborhood Hits	839	Shared Neighborhood Hits	5
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

CCD38_HUMAN
NC score	0.005580 (rank : 28)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	38	Target Neighborhood Hits	287	Shared Neighborhood Hits	2
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

TENX_HUMAN
NC score	0.005278 (rank : 29)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	38	Target Neighborhood Hits	789	Shared Neighborhood Hits	3
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

UBE3A_HUMAN
NC score	0.004421 (rank : 30)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	38	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

ABCF1_MOUSE
NC score	0.004152 (rank : 31)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	38	Target Neighborhood Hits	321	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

ZN746_MOUSE
NC score	0.002946 (rank : 32)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	38	Target Neighborhood Hits	748	Shared Neighborhood Hits	5
SwissProt Accessions	Q3U133	Gene names	Znf746, Zfp746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

BPA1_MOUSE
NC score	0.002791 (rank : 33)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	38	Target Neighborhood Hits	1477	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

KIF14_HUMAN
NC score	0.002111 (rank : 34)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	38	Target Neighborhood Hits	732	Shared Neighborhood Hits	5
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

CCD41_HUMAN
NC score	0.001741 (rank : 35)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	38	Target Neighborhood Hits	1139	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

ZN746_HUMAN
NC score	0.000860 (rank : 36)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	38	Target Neighborhood Hits	745	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NUN9	Gene names	ZNF746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

KPCD_HUMAN
NC score	0.000559 (rank : 37)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	38	Target Neighborhood Hits	900	Shared Neighborhood Hits	4
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

PGFRA_HUMAN
NC score	-0.000052 (rank : 38)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	38	Target Neighborhood Hits	980	Shared Neighborhood Hits	3
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).