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Network neighborhood for query Sequence : VIGLN_MOUSE

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VIGLN_MOUSE
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

VIGLN_HUMAN
θ value	0 (rank : 1)	NC score	0.997803 (rank : 2)
Query Neighborhood Hits	80	Target Neighborhood Hits	71	Shared Neighborhood Hits	65
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

VIGLN_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	80	Target Neighborhood Hits	80	Shared Neighborhood Hits	80
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

FUBP2_HUMAN
θ value	4.30538e-10 (rank : 3)	NC score	0.470560 (rank : 3)
Query Neighborhood Hits	80	Target Neighborhood Hits	145	Shared Neighborhood Hits	29
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

IF2B2_HUMAN
θ value	5.62301e-10 (rank : 4)	NC score	0.429736 (rank : 7)
Query Neighborhood Hits	80	Target Neighborhood Hits	142	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

FUBP1_HUMAN
θ value	1.38499e-08 (rank : 5)	NC score	0.451234 (rank : 5)
Query Neighborhood Hits	80	Target Neighborhood Hits	136	Shared Neighborhood Hits	29
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

FUBP1_MOUSE
θ value	2.36244e-08 (rank : 6)	NC score	0.449051 (rank : 6)
Query Neighborhood Hits	80	Target Neighborhood Hits	144	Shared Neighborhood Hits	29
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

FUBP3_HUMAN
θ value	5.26297e-08 (rank : 7)	NC score	0.458562 (rank : 4)
Query Neighborhood Hits	80	Target Neighborhood Hits	68	Shared Neighborhood Hits	29
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

IF2B2_MOUSE
θ value	1.69304e-06 (rank : 8)	NC score	0.393428 (rank : 8)
Query Neighborhood Hits	80	Target Neighborhood Hits	148	Shared Neighborhood Hits	29
SwissProt Accessions	Q5SF07, Q3TCU4, Q7TQF9	Gene names	Igf2bp2, Imp2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2).

PCBP1_HUMAN
θ value	8.40245e-06 (rank : 9)	NC score	0.384781 (rank : 9)
Query Neighborhood Hits	80	Target Neighborhood Hits	37	Shared Neighborhood Hits	27
SwissProt Accessions	Q15365, Q13157, Q14975	Gene names	PCBP1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1) (Nucleic acid- binding protein SUB2.3).

PCBP1_MOUSE
θ value	8.40245e-06 (rank : 10)	NC score	0.384781 (rank : 10)
Query Neighborhood Hits	80	Target Neighborhood Hits	37	Shared Neighborhood Hits	27
SwissProt Accessions	P60335	Gene names	Pcbp1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1).

PCBP2_MOUSE
θ value	8.40245e-06 (rank : 11)	NC score	0.378487 (rank : 11)
Query Neighborhood Hits	80	Target Neighborhood Hits	47	Shared Neighborhood Hits	26
SwissProt Accessions	Q61990, Q61383, Q62042	Gene names	Pcbp2, Cbp, Hnrnpx, Hnrpx
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP).

PCBP2_HUMAN
θ value	2.44474e-05 (rank : 12)	NC score	0.374297 (rank : 12)
Query Neighborhood Hits	80	Target Neighborhood Hits	45	Shared Neighborhood Hits	26
SwissProt Accessions	Q15366, Q6PKG5	Gene names	PCBP2
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (hnRNP-E2).

TDRKH_HUMAN
θ value	0.00035302 (rank : 13)	NC score	0.323553 (rank : 21)
Query Neighborhood Hits	80	Target Neighborhood Hits	59	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y2W6, Q8N582, Q9NYV5	Gene names	TDRKH, TDRD2
Domain Architecture
Description	Tudor and KH domain-containing protein.

HNRPK_HUMAN
θ value	0.000461057 (rank : 14)	NC score	0.367369 (rank : 13)
Query Neighborhood Hits	80	Target Neighborhood Hits	45	Shared Neighborhood Hits	28
SwissProt Accessions	P61978, Q07244, Q15671, Q60577, Q922Y7, Q96J62	Gene names	HNRPK, HNRNPK
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP).

HNRPK_MOUSE
θ value	0.000461057 (rank : 15)	NC score	0.367369 (rank : 14)
Query Neighborhood Hits	80	Target Neighborhood Hits	45	Shared Neighborhood Hits	28
SwissProt Accessions	P61979, Q07244, Q15671, Q60577, Q8BGQ8, Q922Y7, Q96J62	Gene names	Hnrpk, Hnrnpk
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K.

RKHD1_HUMAN
θ value	0.000786445 (rank : 16)	NC score	0.268073 (rank : 23)
Query Neighborhood Hits	80	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

TDRKH_MOUSE
θ value	0.000786445 (rank : 17)	NC score	0.319567 (rank : 22)
Query Neighborhood Hits	80	Target Neighborhood Hits	59	Shared Neighborhood Hits	27
SwissProt Accessions	Q80VL1	Gene names	Tdrkh
Domain Architecture
Description	Tudor and KH domain-containing protein.

PCBP3_HUMAN
θ value	0.00102713 (rank : 18)	NC score	0.353499 (rank : 18)
Query Neighborhood Hits	80	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	P57721, Q8N9K6, Q96EP6	Gene names	PCBP3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP3_MOUSE
θ value	0.00102713 (rank : 19)	NC score	0.353620 (rank : 17)
Query Neighborhood Hits	80	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	P57722, Q8BSB0, Q8C544	Gene names	Pcbp3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP4_HUMAN
θ value	0.00175202 (rank : 20)	NC score	0.355617 (rank : 16)
Query Neighborhood Hits	80	Target Neighborhood Hits	49	Shared Neighborhood Hits	27
SwissProt Accessions	P57723, Q96AH7	Gene names	PCBP4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

PCBP4_MOUSE
θ value	0.00390308 (rank : 21)	NC score	0.352730 (rank : 19)
Query Neighborhood Hits	80	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	P57724, Q91VR3	Gene names	Pcbp4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

NOVA2_HUMAN
θ value	0.0193708 (rank : 22)	NC score	0.365095 (rank : 15)
Query Neighborhood Hits	80	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UNW9, O43267, Q9UEA1	Gene names	NOVA2, ANOVA, NOVA3
Domain Architecture
Description	RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein).

ASCC1_MOUSE
θ value	0.0330416 (rank : 23)	NC score	0.142080 (rank : 24)
Query Neighborhood Hits	80	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D8Z1, Q3TAC2	Gene names	Ascc1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50).

TMF1_HUMAN
θ value	0.0961366 (rank : 24)	NC score	0.038698 (rank : 45)
Query Neighborhood Hits	80	Target Neighborhood Hits	987	Shared Neighborhood Hits	18
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

ASCC1_HUMAN
θ value	0.163984 (rank : 25)	NC score	0.113117 (rank : 25)
Query Neighborhood Hits	80	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N9N2, Q96EI8, Q9Y307	Gene names	ASCC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50).

FMR1_MOUSE
θ value	0.163984 (rank : 26)	NC score	0.109780 (rank : 26)
Query Neighborhood Hits	80	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	P35922	Gene names	Fmr1, Fmr-1
Domain Architecture
Description	Fragile X mental retardation protein 1 homolog (Protein FMR-1) (FMRP) (mFmr1p).

NOVA1_HUMAN
θ value	0.21417 (rank : 27)	NC score	0.333500 (rank : 20)
Query Neighborhood Hits	80	Target Neighborhood Hits	50	Shared Neighborhood Hits	28
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

PAR14_MOUSE
θ value	0.21417 (rank : 28)	NC score	0.058721 (rank : 34)
Query Neighborhood Hits	80	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

FMR1_HUMAN
θ value	0.279714 (rank : 29)	NC score	0.108081 (rank : 27)
Query Neighborhood Hits	80	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	Q06787, Q16578, Q99054	Gene names	FMR1
Domain Architecture
Description	Fragile X mental retardation 1 protein (Protein FMR-1) (FMRP).

LMBL3_MOUSE
θ value	0.365318 (rank : 30)	NC score	0.034677 (rank : 47)
Query Neighborhood Hits	80	Target Neighborhood Hits	212	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

DDX43_HUMAN
θ value	0.47712 (rank : 31)	NC score	0.044736 (rank : 43)
Query Neighborhood Hits	80	Target Neighborhood Hits	120	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX53_HUMAN
θ value	0.62314 (rank : 32)	NC score	0.048252 (rank : 40)
Query Neighborhood Hits	80	Target Neighborhood Hits	124	Shared Neighborhood Hits	23
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

E2F6_MOUSE
θ value	0.62314 (rank : 33)	NC score	0.045942 (rank : 41)
Query Neighborhood Hits	80	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	O54917	Gene names	E2f6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA).

FES_HUMAN
θ value	0.62314 (rank : 34)	NC score	0.007371 (rank : 78)
Query Neighborhood Hits	80	Target Neighborhood Hits	978	Shared Neighborhood Hits	11
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

PFD4_HUMAN
θ value	0.813845 (rank : 35)	NC score	0.100952 (rank : 29)
Query Neighborhood Hits	80	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQP4, Q5TD11, Q92779	Gene names	PFDN4, PFD4
Domain Architecture	No domain graphic available
Description	Prefoldin subunit 4 (Protein C-1).

FXR1_HUMAN
θ value	1.06291 (rank : 36)	NC score	0.105028 (rank : 28)
Query Neighborhood Hits	80	Target Neighborhood Hits	50	Shared Neighborhood Hits	26
SwissProt Accessions	P51114, Q7Z450, Q8N6R8	Gene names	FXR1
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (hFXR1P).

K0323_HUMAN
θ value	1.06291 (rank : 37)	NC score	0.058581 (rank : 35)
Query Neighborhood Hits	80	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	O15037, Q86TZ6, Q8IUQ2, Q96BA9	Gene names	KIAA0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

NFX1_HUMAN
θ value	1.06291 (rank : 38)	NC score	0.045209 (rank : 42)
Query Neighborhood Hits	80	Target Neighborhood Hits	405	Shared Neighborhood Hits	4
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

SM1L2_MOUSE
θ value	1.06291 (rank : 39)	NC score	0.024084 (rank : 50)
Query Neighborhood Hits	80	Target Neighborhood Hits	918	Shared Neighborhood Hits	17
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

WNK1_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.010875 (rank : 70)
Query Neighborhood Hits	80	Target Neighborhood Hits	1158	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

RT36_HUMAN
θ value	1.38821 (rank : 41)	NC score	0.049607 (rank : 39)
Query Neighborhood Hits	80	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P82909, Q9H2H4	Gene names	MRPS36
Domain Architecture	No domain graphic available
Description	Mitochondrial 28S ribosomal protein S36 (S36mt) (MRP-S36).

CI039_HUMAN
θ value	1.81305 (rank : 42)	NC score	0.019749 (rank : 52)
Query Neighborhood Hits	80	Target Neighborhood Hits	1171	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

M3K4_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.008137 (rank : 75)
Query Neighborhood Hits	80	Target Neighborhood Hits	911	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

CLIC6_MOUSE
θ value	2.36792 (rank : 44)	NC score	0.025007 (rank : 49)
Query Neighborhood Hits	80	Target Neighborhood Hits	134	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHB9	Gene names	Clic6
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

PAR14_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.041906 (rank : 44)
Query Neighborhood Hits	80	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q460N5, Q460N4, Q8J027, Q9H9X9, Q9NV60, Q9ULF2	Gene names	PARP14, BAL2, KIAA1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (B aggressive lymphoma protein 2).

FXR1_MOUSE
θ value	3.0926 (rank : 46)	NC score	0.097182 (rank : 30)
Query Neighborhood Hits	80	Target Neighborhood Hits	49	Shared Neighborhood Hits	26
SwissProt Accessions	Q61584, Q8VCU4, Q9R1E2, Q9R1E3, Q9R1E4, Q9R1E5, Q9WUA7, Q9WUA8, Q9WUA9	Gene names	Fxr1, Fxr1h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (mFxr1p).

SEN2_MOUSE
θ value	3.0926 (rank : 47)	NC score	0.035739 (rank : 46)
Query Neighborhood Hits	80	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P7W5, Q3UYG6	Gene names	Tsen2, Sen2
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2).

AMZ1_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.019482 (rank : 53)
Query Neighborhood Hits	80	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q400G9, Q8TF51	Gene names	AMZ1, KIAA1950
Domain Architecture	No domain graphic available
Description	Archaemetzincin-1 (EC 3.-.-.-) (Archeobacterial metalloproteinase-like protein 1).

GAS8_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.017305 (rank : 55)
Query Neighborhood Hits	80	Target Neighborhood Hits	819	Shared Neighborhood Hits	15
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

HXA9_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.007338 (rank : 79)
Query Neighborhood Hits	80	Target Neighborhood Hits	332	Shared Neighborhood Hits	3
SwissProt Accessions	P31269, O43369, O43429, Q99820	Gene names	HOXA9, HOX1G
Domain Architecture
Description	Homeobox protein Hox-A9 (Hox-1G).

HXA9_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.007293 (rank : 80)
Query Neighborhood Hits	80	Target Neighborhood Hits	334	Shared Neighborhood Hits	3
SwissProt Accessions	P09631, O70154, O70155	Gene names	Hoxa9, Hox-1.7, Hoxa-9
Domain Architecture
Description	Homeobox protein Hox-A9 (Hox-1.7).

ITIH3_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.012133 (rank : 62)
Query Neighborhood Hits	80	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q06033, Q99085	Gene names	ITIH3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3) (Serum-derived hyaluronan-associated protein) (SHAP).

KPCD1_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.004351 (rank : 85)
Query Neighborhood Hits	80	Target Neighborhood Hits	901	Shared Neighborhood Hits	7
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

LAMC1_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.009247 (rank : 72)
Query Neighborhood Hits	80	Target Neighborhood Hits	856	Shared Neighborhood Hits	15
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

M3K4_MOUSE
θ value	4.03905 (rank : 55)	NC score	0.006767 (rank : 82)
Query Neighborhood Hits	80	Target Neighborhood Hits	924	Shared Neighborhood Hits	8
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

PLXA4_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.011364 (rank : 68)
Query Neighborhood Hits	80	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCM2, Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4	Gene names	PLXNA4, KIAA1550, PLXNA4A, PLXNA4B
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXA4_MOUSE
θ value	4.03905 (rank : 57)	NC score	0.011376 (rank : 67)
Query Neighborhood Hits	80	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UG2, Q5DTW8, Q8BKK9	Gene names	Plxna4, Kiaa1550
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

SCN8A_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.011221 (rank : 69)
Query Neighborhood Hits	80	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

AT1A1_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.011732 (rank : 64)
Query Neighborhood Hits	80	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	P05023, Q16689, Q6LDM4, Q9UJ20, Q9UJ21	Gene names	ATP1A1
Domain Architecture
Description	Sodium/potassium-transporting ATPase alpha-1 chain precursor (EC 3.6.3.9) (Sodium pump 1) (Na+/K+ ATPase 1).

AT1A1_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.011709 (rank : 65)
Query Neighborhood Hits	80	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDN2, Q91Z09	Gene names	Atp1a1
Domain Architecture
Description	Sodium/potassium-transporting ATPase alpha-1 chain precursor (EC 3.6.3.9) (Sodium pump 1) (Na+/K+ ATPase 1).

EEA1_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.012457 (rank : 60)
Query Neighborhood Hits	80	Target Neighborhood Hits	1796	Shared Neighborhood Hits	22
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

MDC1_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.008447 (rank : 74)
Query Neighborhood Hits	80	Target Neighborhood Hits	998	Shared Neighborhood Hits	5
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NCOR2_MOUSE
θ value	5.27518 (rank : 63)	NC score	0.016125 (rank : 56)
Query Neighborhood Hits	80	Target Neighborhood Hits	790	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PFD2_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.026027 (rank : 48)
Query Neighborhood Hits	80	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	O70591, Q8R0H2	Gene names	Pfdn2, Pfd2
Domain Architecture
Description	Prefoldin subunit 2.

SYCP1_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.013791 (rank : 58)
Query Neighborhood Hits	80	Target Neighborhood Hits	1313	Shared Neighborhood Hits	17
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CF060_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.012200 (rank : 61)
Query Neighborhood Hits	80	Target Neighborhood Hits	1270	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

HMMR_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.010793 (rank : 71)
Query Neighborhood Hits	80	Target Neighborhood Hits	1178	Shared Neighborhood Hits	17
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HOOK1_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.013098 (rank : 59)
Query Neighborhood Hits	80	Target Neighborhood Hits	910	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

MYH8_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.005363 (rank : 84)
Query Neighborhood Hits	80	Target Neighborhood Hits	1610	Shared Neighborhood Hits	18
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

ZC3H8_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.012049 (rank : 63)
Query Neighborhood Hits	80	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N5P1, Q9BZ75	Gene names	ZC3H8, ZC3HDC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8.

CJ118_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.011585 (rank : 66)
Query Neighborhood Hits	80	Target Neighborhood Hits	1132	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CMTA1_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.017790 (rank : 54)
Query Neighborhood Hits	80	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

JPH4_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.007159 (rank : 81)
Query Neighborhood Hits	80	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q96JJ6, Q8ND44, Q96DQ0	Gene names	JPH4, JPHL1, KIAA1831
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

KI21B_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.005429 (rank : 83)
Query Neighborhood Hits	80	Target Neighborhood Hits	1017	Shared Neighborhood Hits	13
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

MAP2_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.015864 (rank : 57)
Query Neighborhood Hits	80	Target Neighborhood Hits	348	Shared Neighborhood Hits	8
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

MATN1_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.007508 (rank : 77)
Query Neighborhood Hits	80	Target Neighborhood Hits	191	Shared Neighborhood Hits	3
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

PCNT_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.009063 (rank : 73)
Query Neighborhood Hits	80	Target Neighborhood Hits	1551	Shared Neighborhood Hits	20
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RM44_MOUSE
θ value	8.99809 (rank : 78)	NC score	0.023595 (rank : 51)
Query Neighborhood Hits	80	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CY73, Q8VE61	Gene names	Mrpl44
Domain Architecture	No domain graphic available
Description	39S ribosomal protein L44, mitochondrial precursor (EC 3.1.26.-) (L44mt) (MRP-L44).

SPA3N_MOUSE
θ value	8.99809 (rank : 79)	NC score	0.002203 (rank : 86)
Query Neighborhood Hits	80	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WP6, Q62258	Gene names	Serpina3n, Spi2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3N precursor (Serpin A3N).

TOP2A_MOUSE
θ value	8.99809 (rank : 80)	NC score	0.007838 (rank : 76)
Query Neighborhood Hits	80	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

AKAP1_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.080180 (rank : 31)
Query Neighborhood Hits	80	Target Neighborhood Hits	88	Shared Neighborhood Hits	24
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

AKAP1_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.075814 (rank : 33)
Query Neighborhood Hits	80	Target Neighborhood Hits	198	Shared Neighborhood Hits	27
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

FXR2_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.076949 (rank : 32)
Query Neighborhood Hits	80	Target Neighborhood Hits	77	Shared Neighborhood Hits	24
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

FXR2_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.054654 (rank : 36)
Query Neighborhood Hits	80	Target Neighborhood Hits	66	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

SAM68_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.053233 (rank : 37)
Query Neighborhood Hits	80	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SAM68_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.050894 (rank : 38)
Query Neighborhood Hits	80	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

Hits sorted by NC score

VIGLN_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	80	Target Neighborhood Hits	80	Shared Neighborhood Hits	80
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

VIGLN_HUMAN
NC score	0.997803 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	80	Target Neighborhood Hits	71	Shared Neighborhood Hits	65
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

FUBP2_HUMAN
NC score	0.470560 (rank : 3)	θ value	4.30538e-10 (rank : 3)
Query Neighborhood Hits	80	Target Neighborhood Hits	145	Shared Neighborhood Hits	29
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

FUBP3_HUMAN
NC score	0.458562 (rank : 4)	θ value	5.26297e-08 (rank : 7)
Query Neighborhood Hits	80	Target Neighborhood Hits	68	Shared Neighborhood Hits	29
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

FUBP1_HUMAN
NC score	0.451234 (rank : 5)	θ value	1.38499e-08 (rank : 5)
Query Neighborhood Hits	80	Target Neighborhood Hits	136	Shared Neighborhood Hits	29
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

FUBP1_MOUSE
NC score	0.449051 (rank : 6)	θ value	2.36244e-08 (rank : 6)
Query Neighborhood Hits	80	Target Neighborhood Hits	144	Shared Neighborhood Hits	29
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

IF2B2_HUMAN
NC score	0.429736 (rank : 7)	θ value	5.62301e-10 (rank : 4)
Query Neighborhood Hits	80	Target Neighborhood Hits	142	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

IF2B2_MOUSE
NC score	0.393428 (rank : 8)	θ value	1.69304e-06 (rank : 8)
Query Neighborhood Hits	80	Target Neighborhood Hits	148	Shared Neighborhood Hits	29
SwissProt Accessions	Q5SF07, Q3TCU4, Q7TQF9	Gene names	Igf2bp2, Imp2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2).

PCBP1_HUMAN
NC score	0.384781 (rank : 9)	θ value	8.40245e-06 (rank : 9)
Query Neighborhood Hits	80	Target Neighborhood Hits	37	Shared Neighborhood Hits	27
SwissProt Accessions	Q15365, Q13157, Q14975	Gene names	PCBP1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1) (Nucleic acid- binding protein SUB2.3).

PCBP1_MOUSE
NC score	0.384781 (rank : 10)	θ value	8.40245e-06 (rank : 10)
Query Neighborhood Hits	80	Target Neighborhood Hits	37	Shared Neighborhood Hits	27
SwissProt Accessions	P60335	Gene names	Pcbp1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1).

PCBP2_MOUSE
NC score	0.378487 (rank : 11)	θ value	8.40245e-06 (rank : 11)
Query Neighborhood Hits	80	Target Neighborhood Hits	47	Shared Neighborhood Hits	26
SwissProt Accessions	Q61990, Q61383, Q62042	Gene names	Pcbp2, Cbp, Hnrnpx, Hnrpx
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP).

PCBP2_HUMAN
NC score	0.374297 (rank : 12)	θ value	2.44474e-05 (rank : 12)
Query Neighborhood Hits	80	Target Neighborhood Hits	45	Shared Neighborhood Hits	26
SwissProt Accessions	Q15366, Q6PKG5	Gene names	PCBP2
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (hnRNP-E2).

HNRPK_HUMAN
NC score	0.367369 (rank : 13)	θ value	0.000461057 (rank : 14)
Query Neighborhood Hits	80	Target Neighborhood Hits	45	Shared Neighborhood Hits	28
SwissProt Accessions	P61978, Q07244, Q15671, Q60577, Q922Y7, Q96J62	Gene names	HNRPK, HNRNPK
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP).

HNRPK_MOUSE
NC score	0.367369 (rank : 14)	θ value	0.000461057 (rank : 15)
Query Neighborhood Hits	80	Target Neighborhood Hits	45	Shared Neighborhood Hits	28
SwissProt Accessions	P61979, Q07244, Q15671, Q60577, Q8BGQ8, Q922Y7, Q96J62	Gene names	Hnrpk, Hnrnpk
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K.

NOVA2_HUMAN
NC score	0.365095 (rank : 15)	θ value	0.0193708 (rank : 22)
Query Neighborhood Hits	80	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UNW9, O43267, Q9UEA1	Gene names	NOVA2, ANOVA, NOVA3
Domain Architecture
Description	RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein).

PCBP4_HUMAN
NC score	0.355617 (rank : 16)	θ value	0.00175202 (rank : 20)
Query Neighborhood Hits	80	Target Neighborhood Hits	49	Shared Neighborhood Hits	27
SwissProt Accessions	P57723, Q96AH7	Gene names	PCBP4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

PCBP3_MOUSE
NC score	0.353620 (rank : 17)	θ value	0.00102713 (rank : 19)
Query Neighborhood Hits	80	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	P57722, Q8BSB0, Q8C544	Gene names	Pcbp3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP3_HUMAN
NC score	0.353499 (rank : 18)	θ value	0.00102713 (rank : 18)
Query Neighborhood Hits	80	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	P57721, Q8N9K6, Q96EP6	Gene names	PCBP3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP4_MOUSE
NC score	0.352730 (rank : 19)	θ value	0.00390308 (rank : 21)
Query Neighborhood Hits	80	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	P57724, Q91VR3	Gene names	Pcbp4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

NOVA1_HUMAN
NC score	0.333500 (rank : 20)	θ value	0.21417 (rank : 27)
Query Neighborhood Hits	80	Target Neighborhood Hits	50	Shared Neighborhood Hits	28
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

TDRKH_HUMAN
NC score	0.323553 (rank : 21)	θ value	0.00035302 (rank : 13)
Query Neighborhood Hits	80	Target Neighborhood Hits	59	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y2W6, Q8N582, Q9NYV5	Gene names	TDRKH, TDRD2
Domain Architecture
Description	Tudor and KH domain-containing protein.

TDRKH_MOUSE
NC score	0.319567 (rank : 22)	θ value	0.000786445 (rank : 17)
Query Neighborhood Hits	80	Target Neighborhood Hits	59	Shared Neighborhood Hits	27
SwissProt Accessions	Q80VL1	Gene names	Tdrkh
Domain Architecture
Description	Tudor and KH domain-containing protein.

RKHD1_HUMAN
NC score	0.268073 (rank : 23)	θ value	0.000786445 (rank : 16)
Query Neighborhood Hits	80	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

ASCC1_MOUSE
NC score	0.142080 (rank : 24)	θ value	0.0330416 (rank : 23)
Query Neighborhood Hits	80	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D8Z1, Q3TAC2	Gene names	Ascc1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50).

ASCC1_HUMAN
NC score	0.113117 (rank : 25)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	80	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N9N2, Q96EI8, Q9Y307	Gene names	ASCC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50).

FMR1_MOUSE
NC score	0.109780 (rank : 26)	θ value	0.163984 (rank : 26)
Query Neighborhood Hits	80	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	P35922	Gene names	Fmr1, Fmr-1
Domain Architecture
Description	Fragile X mental retardation protein 1 homolog (Protein FMR-1) (FMRP) (mFmr1p).

FMR1_HUMAN
NC score	0.108081 (rank : 27)	θ value	0.279714 (rank : 29)
Query Neighborhood Hits	80	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	Q06787, Q16578, Q99054	Gene names	FMR1
Domain Architecture
Description	Fragile X mental retardation 1 protein (Protein FMR-1) (FMRP).

FXR1_HUMAN
NC score	0.105028 (rank : 28)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	80	Target Neighborhood Hits	50	Shared Neighborhood Hits	26
SwissProt Accessions	P51114, Q7Z450, Q8N6R8	Gene names	FXR1
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (hFXR1P).

PFD4_HUMAN
NC score	0.100952 (rank : 29)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	80	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQP4, Q5TD11, Q92779	Gene names	PFDN4, PFD4
Domain Architecture	No domain graphic available
Description	Prefoldin subunit 4 (Protein C-1).

FXR1_MOUSE
NC score	0.097182 (rank : 30)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	80	Target Neighborhood Hits	49	Shared Neighborhood Hits	26
SwissProt Accessions	Q61584, Q8VCU4, Q9R1E2, Q9R1E3, Q9R1E4, Q9R1E5, Q9WUA7, Q9WUA8, Q9WUA9	Gene names	Fxr1, Fxr1h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (mFxr1p).

AKAP1_HUMAN
NC score	0.080180 (rank : 31)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	80	Target Neighborhood Hits	88	Shared Neighborhood Hits	24
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

FXR2_HUMAN
NC score	0.076949 (rank : 32)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	80	Target Neighborhood Hits	77	Shared Neighborhood Hits	24
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

AKAP1_MOUSE
NC score	0.075814 (rank : 33)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	80	Target Neighborhood Hits	198	Shared Neighborhood Hits	27
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

PAR14_MOUSE
NC score	0.058721 (rank : 34)	θ value	0.21417 (rank : 28)
Query Neighborhood Hits	80	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

K0323_HUMAN
NC score	0.058581 (rank : 35)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	80	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	O15037, Q86TZ6, Q8IUQ2, Q96BA9	Gene names	KIAA0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

FXR2_MOUSE
NC score	0.054654 (rank : 36)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	80	Target Neighborhood Hits	66	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

SAM68_HUMAN
NC score	0.053233 (rank : 37)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	80	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SAM68_MOUSE
NC score	0.050894 (rank : 38)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	80	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

RT36_HUMAN
NC score	0.049607 (rank : 39)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	80	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P82909, Q9H2H4	Gene names	MRPS36
Domain Architecture	No domain graphic available
Description	Mitochondrial 28S ribosomal protein S36 (S36mt) (MRP-S36).

DDX53_HUMAN
NC score	0.048252 (rank : 40)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	80	Target Neighborhood Hits	124	Shared Neighborhood Hits	23
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

E2F6_MOUSE
NC score	0.045942 (rank : 41)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	80	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	O54917	Gene names	E2f6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA).

NFX1_HUMAN
NC score	0.045209 (rank : 42)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	80	Target Neighborhood Hits	405	Shared Neighborhood Hits	4
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

DDX43_HUMAN
NC score	0.044736 (rank : 43)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	80	Target Neighborhood Hits	120	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

PAR14_HUMAN
NC score	0.041906 (rank : 44)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	80	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q460N5, Q460N4, Q8J027, Q9H9X9, Q9NV60, Q9ULF2	Gene names	PARP14, BAL2, KIAA1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (B aggressive lymphoma protein 2).

TMF1_HUMAN
NC score	0.038698 (rank : 45)	θ value	0.0961366 (rank : 24)
Query Neighborhood Hits	80	Target Neighborhood Hits	987	Shared Neighborhood Hits	18
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

SEN2_MOUSE
NC score	0.035739 (rank : 46)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	80	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P7W5, Q3UYG6	Gene names	Tsen2, Sen2
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2).

LMBL3_MOUSE
NC score	0.034677 (rank : 47)	θ value	0.365318 (rank : 30)
Query Neighborhood Hits	80	Target Neighborhood Hits	212	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

PFD2_MOUSE
NC score	0.026027 (rank : 48)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	80	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	O70591, Q8R0H2	Gene names	Pfdn2, Pfd2
Domain Architecture
Description	Prefoldin subunit 2.

CLIC6_MOUSE
NC score	0.025007 (rank : 49)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	80	Target Neighborhood Hits	134	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHB9	Gene names	Clic6
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

SM1L2_MOUSE
NC score	0.024084 (rank : 50)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	80	Target Neighborhood Hits	918	Shared Neighborhood Hits	17
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

RM44_MOUSE
NC score	0.023595 (rank : 51)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	80	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CY73, Q8VE61	Gene names	Mrpl44
Domain Architecture	No domain graphic available
Description	39S ribosomal protein L44, mitochondrial precursor (EC 3.1.26.-) (L44mt) (MRP-L44).

CI039_HUMAN
NC score	0.019749 (rank : 52)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	80	Target Neighborhood Hits	1171	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

AMZ1_HUMAN
NC score	0.019482 (rank : 53)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	80	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q400G9, Q8TF51	Gene names	AMZ1, KIAA1950
Domain Architecture	No domain graphic available
Description	Archaemetzincin-1 (EC 3.-.-.-) (Archeobacterial metalloproteinase-like protein 1).

CMTA1_HUMAN
NC score	0.017790 (rank : 54)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	80	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

GAS8_HUMAN
NC score	0.017305 (rank : 55)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	80	Target Neighborhood Hits	819	Shared Neighborhood Hits	15
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

NCOR2_MOUSE
NC score	0.016125 (rank : 56)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	80	Target Neighborhood Hits	790	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

MAP2_HUMAN
NC score	0.015864 (rank : 57)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	80	Target Neighborhood Hits	348	Shared Neighborhood Hits	8
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

SYCP1_HUMAN
NC score	0.013791 (rank : 58)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	80	Target Neighborhood Hits	1313	Shared Neighborhood Hits	17
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

HOOK1_MOUSE
NC score	0.013098 (rank : 59)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	80	Target Neighborhood Hits	910	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

EEA1_HUMAN
NC score	0.012457 (rank : 60)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	80	Target Neighborhood Hits	1796	Shared Neighborhood Hits	22
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

CF060_HUMAN
NC score	0.012200 (rank : 61)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	80	Target Neighborhood Hits	1270	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

ITIH3_HUMAN
NC score	0.012133 (rank : 62)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	80	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q06033, Q99085	Gene names	ITIH3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3) (Serum-derived hyaluronan-associated protein) (SHAP).

ZC3H8_HUMAN
NC score	0.012049 (rank : 63)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	80	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N5P1, Q9BZ75	Gene names	ZC3H8, ZC3HDC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8.

AT1A1_HUMAN
NC score	0.011732 (rank : 64)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	80	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	P05023, Q16689, Q6LDM4, Q9UJ20, Q9UJ21	Gene names	ATP1A1
Domain Architecture
Description	Sodium/potassium-transporting ATPase alpha-1 chain precursor (EC 3.6.3.9) (Sodium pump 1) (Na+/K+ ATPase 1).

AT1A1_MOUSE
NC score	0.011709 (rank : 65)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	80	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDN2, Q91Z09	Gene names	Atp1a1
Domain Architecture
Description	Sodium/potassium-transporting ATPase alpha-1 chain precursor (EC 3.6.3.9) (Sodium pump 1) (Na+/K+ ATPase 1).

CJ118_MOUSE
NC score	0.011585 (rank : 66)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	80	Target Neighborhood Hits	1132	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

PLXA4_MOUSE
NC score	0.011376 (rank : 67)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	80	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UG2, Q5DTW8, Q8BKK9	Gene names	Plxna4, Kiaa1550
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXA4_HUMAN
NC score	0.011364 (rank : 68)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	80	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCM2, Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4	Gene names	PLXNA4, KIAA1550, PLXNA4A, PLXNA4B
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

SCN8A_MOUSE
NC score	0.011221 (rank : 69)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	80	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

WNK1_HUMAN
NC score	0.010875 (rank : 70)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	80	Target Neighborhood Hits	1158	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

HMMR_MOUSE
NC score	0.010793 (rank : 71)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	80	Target Neighborhood Hits	1178	Shared Neighborhood Hits	17
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

LAMC1_MOUSE
NC score	0.009247 (rank : 72)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	80	Target Neighborhood Hits	856	Shared Neighborhood Hits	15
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

PCNT_HUMAN
NC score	0.009063 (rank : 73)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	80	Target Neighborhood Hits	1551	Shared Neighborhood Hits	20
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

MDC1_MOUSE
NC score	0.008447 (rank : 74)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	80	Target Neighborhood Hits	998	Shared Neighborhood Hits	5
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

M3K4_HUMAN
NC score	0.008137 (rank : 75)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	80	Target Neighborhood Hits	911	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

TOP2A_MOUSE
NC score	0.007838 (rank : 76)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	80	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

MATN1_HUMAN
NC score	0.007508 (rank : 77)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	80	Target Neighborhood Hits	191	Shared Neighborhood Hits	3
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

FES_HUMAN
NC score	0.007371 (rank : 78)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	80	Target Neighborhood Hits	978	Shared Neighborhood Hits	11
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

HXA9_HUMAN
NC score	0.007338 (rank : 79)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	80	Target Neighborhood Hits	332	Shared Neighborhood Hits	3
SwissProt Accessions	P31269, O43369, O43429, Q99820	Gene names	HOXA9, HOX1G
Domain Architecture
Description	Homeobox protein Hox-A9 (Hox-1G).

HXA9_MOUSE
NC score	0.007293 (rank : 80)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	80	Target Neighborhood Hits	334	Shared Neighborhood Hits	3
SwissProt Accessions	P09631, O70154, O70155	Gene names	Hoxa9, Hox-1.7, Hoxa-9
Domain Architecture
Description	Homeobox protein Hox-A9 (Hox-1.7).

JPH4_HUMAN
NC score	0.007159 (rank : 81)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	80	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q96JJ6, Q8ND44, Q96DQ0	Gene names	JPH4, JPHL1, KIAA1831
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

M3K4_MOUSE
NC score	0.006767 (rank : 82)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	80	Target Neighborhood Hits	924	Shared Neighborhood Hits	8
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

KI21B_HUMAN
NC score	0.005429 (rank : 83)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	80	Target Neighborhood Hits	1017	Shared Neighborhood Hits	13
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

MYH8_HUMAN
NC score	0.005363 (rank : 84)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	80	Target Neighborhood Hits	1610	Shared Neighborhood Hits	18
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

KPCD1_HUMAN
NC score	0.004351 (rank : 85)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	80	Target Neighborhood Hits	901	Shared Neighborhood Hits	7
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

SPA3N_MOUSE
NC score	0.002203 (rank : 86)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	80	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WP6, Q62258	Gene names	Serpina3n, Spi2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3N precursor (Serpin A3N).