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Network neighborhood for query Sequence : HNRPK_HUMAN

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HNRPK_HUMAN
SwissProt Accessions	P61978, Q07244, Q15671, Q60577, Q922Y7, Q96J62	Gene names	HNRPK, HNRNPK
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HNRPK_HUMAN
θ value	3.24166e-183 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	P61978, Q07244, Q15671, Q60577, Q922Y7, Q96J62	Gene names	HNRPK, HNRNPK
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP).

HNRPK_MOUSE
θ value	3.24166e-183 (rank : 2)	NC score	0.999962 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	P61979, Q07244, Q15671, Q60577, Q8BGQ8, Q922Y7, Q96J62	Gene names	Hnrpk, Hnrnpk
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K.

PCBP2_HUMAN
θ value	1.08726e-37 (rank : 3)	NC score	0.865185 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	Q15366, Q6PKG5	Gene names	PCBP2
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (hnRNP-E2).

PCBP2_MOUSE
θ value	1.42001e-37 (rank : 4)	NC score	0.864804 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	47	Shared Neighborhood Hits	30
SwissProt Accessions	Q61990, Q61383, Q62042	Gene names	Pcbp2, Cbp, Hnrnpx, Hnrpx
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP).

PCBP1_HUMAN
θ value	1.0531e-32 (rank : 5)	NC score	0.859537 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q15365, Q13157, Q14975	Gene names	PCBP1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1) (Nucleic acid- binding protein SUB2.3).

PCBP1_MOUSE
θ value	1.0531e-32 (rank : 6)	NC score	0.859537 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	P60335	Gene names	Pcbp1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1).

PCBP4_MOUSE
θ value	4.15078e-21 (rank : 7)	NC score	0.824960 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	P57724, Q91VR3	Gene names	Pcbp4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

PCBP4_HUMAN
θ value	7.0802e-21 (rank : 8)	NC score	0.822996 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	P57723, Q96AH7	Gene names	PCBP4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

PCBP3_HUMAN
θ value	1.24977e-17 (rank : 9)	NC score	0.816430 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	P57721, Q8N9K6, Q96EP6	Gene names	PCBP3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP3_MOUSE
θ value	1.24977e-17 (rank : 10)	NC score	0.816485 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	P57722, Q8BSB0, Q8C544	Gene names	Pcbp3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

NOVA2_HUMAN
θ value	4.59992e-12 (rank : 11)	NC score	0.722887 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UNW9, O43267, Q9UEA1	Gene names	NOVA2, ANOVA, NOVA3
Domain Architecture
Description	RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein).

NOVA1_HUMAN
θ value	3.08544e-08 (rank : 12)	NC score	0.706332 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	50	Shared Neighborhood Hits	32
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

FUBP1_HUMAN
θ value	4.45536e-07 (rank : 13)	NC score	0.557484 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	136	Shared Neighborhood Hits	32
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

FUBP1_MOUSE
θ value	4.45536e-07 (rank : 14)	NC score	0.558368 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	144	Shared Neighborhood Hits	32
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

FUBP3_HUMAN
θ value	9.92553e-07 (rank : 15)	NC score	0.587083 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

FUBP2_HUMAN
θ value	1.29631e-06 (rank : 16)	NC score	0.566644 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	145	Shared Neighborhood Hits	32
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

IF2B2_HUMAN
θ value	1.29631e-06 (rank : 17)	NC score	0.531099 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	142	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

IF2B2_MOUSE
θ value	0.000158464 (rank : 18)	NC score	0.512008 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	148	Shared Neighborhood Hits	32
SwissProt Accessions	Q5SF07, Q3TCU4, Q7TQF9	Gene names	Igf2bp2, Imp2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2).

VIGLN_HUMAN
θ value	0.000461057 (rank : 19)	NC score	0.367879 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

VIGLN_MOUSE
θ value	0.000461057 (rank : 20)	NC score	0.367369 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

TDRKH_HUMAN
θ value	0.00869519 (rank : 21)	NC score	0.411653 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	59	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y2W6, Q8N582, Q9NYV5	Gene names	TDRKH, TDRD2
Domain Architecture
Description	Tudor and KH domain-containing protein.

TDRKH_MOUSE
θ value	0.00869519 (rank : 22)	NC score	0.409047 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	59	Shared Neighborhood Hits	30
SwissProt Accessions	Q80VL1	Gene names	Tdrkh
Domain Architecture
Description	Tudor and KH domain-containing protein.

AKAP1_HUMAN
θ value	0.0193708 (rank : 23)	NC score	0.241076 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	88	Shared Neighborhood Hits	29
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

AKAP1_MOUSE
θ value	0.0193708 (rank : 24)	NC score	0.229765 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	198	Shared Neighborhood Hits	28
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

FXR2_HUMAN
θ value	0.0330416 (rank : 25)	NC score	0.171333 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

FXR1_HUMAN
θ value	0.0563607 (rank : 26)	NC score	0.169149 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	P51114, Q7Z450, Q8N6R8	Gene names	FXR1
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (hFXR1P).

FXR1_MOUSE
θ value	0.0563607 (rank : 27)	NC score	0.167599 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	49	Shared Neighborhood Hits	31
SwissProt Accessions	Q61584, Q8VCU4, Q9R1E2, Q9R1E3, Q9R1E4, Q9R1E5, Q9WUA7, Q9WUA8, Q9WUA9	Gene names	Fxr1, Fxr1h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (mFxr1p).

DDX53_HUMAN
θ value	0.0736092 (rank : 28)	NC score	0.063357 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	124	Shared Neighborhood Hits	22
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

FXR2_MOUSE
θ value	0.0736092 (rank : 29)	NC score	0.130524 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	66	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

ASXL1_HUMAN
θ value	0.21417 (rank : 30)	NC score	0.055325 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	260	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

DLG5_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.016061 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	1088	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

PANK1_HUMAN
θ value	1.38821 (rank : 32)	NC score	0.027899 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TE04, Q7RTX6, Q7Z495, Q8TBQ8	Gene names	PANK1, PANK
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (hPanK1) (hPanK).

DDX43_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.048380 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

LAP4_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.009414 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	608	Shared Neighborhood Hits	4
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

FRM4A_MOUSE
θ value	3.0926 (rank : 35)	NC score	0.018351 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

MYO15_HUMAN
θ value	4.03905 (rank : 36)	NC score	0.006257 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	671	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

ZBT17_HUMAN
θ value	4.03905 (rank : 37)	NC score	-0.001371 (rank : 48)
Query Neighborhood Hits	45	Target Neighborhood Hits	925	Shared Neighborhood Hits	3
SwissProt Accessions	Q13105, Q15932, Q5JYB2, Q9NUC9	Gene names	ZBTB17, MIZ1, ZNF151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Myc-interacting zinc finger protein) (Miz-1 protein).

FER_HUMAN
θ value	5.27518 (rank : 38)	NC score	-0.001221 (rank : 47)
Query Neighborhood Hits	45	Target Neighborhood Hits	1278	Shared Neighborhood Hits	3
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

PNPT1_HUMAN
θ value	5.27518 (rank : 39)	NC score	0.054561 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	30	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TCS8, Q53SU0, Q68CN1, Q7Z7D1, Q8IWX1, Q96T05, Q9BRU3, Q9BVX0	Gene names	PNPT1, PNPASE
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

PNPT1_MOUSE
θ value	5.27518 (rank : 40)	NC score	0.050350 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1R3, Q3UEP9, Q810U7, Q812B3, Q8R2U3, Q9DC52	Gene names	Pnpt1, Pnpase
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

FMR1_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.118952 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	Q06787, Q16578, Q99054	Gene names	FMR1
Domain Architecture
Description	Fragile X mental retardation 1 protein (Protein FMR-1) (FMRP).

FMR1_MOUSE
θ value	6.88961 (rank : 42)	NC score	0.118250 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	P35922	Gene names	Fmr1, Fmr-1
Domain Architecture
Description	Fragile X mental retardation protein 1 homolog (Protein FMR-1) (FMRP) (mFmr1p).

FRM4A_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.015112 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

JIP1_HUMAN
θ value	6.88961 (rank : 44)	NC score	0.016721 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

DMBT1_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.004937 (rank : 46)
Query Neighborhood Hits	45	Target Neighborhood Hits	152	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

RKHD1_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.168708 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

SAM68_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.093073 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	68	Shared Neighborhood Hits	20
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SAM68_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.090444 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	65	Shared Neighborhood Hits	20
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

Hits sorted by NC score

HNRPK_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.24166e-183 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	P61978, Q07244, Q15671, Q60577, Q922Y7, Q96J62	Gene names	HNRPK, HNRNPK
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP).

HNRPK_MOUSE
NC score	0.999962 (rank : 2)	θ value	3.24166e-183 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	P61979, Q07244, Q15671, Q60577, Q8BGQ8, Q922Y7, Q96J62	Gene names	Hnrpk, Hnrnpk
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K.

PCBP2_HUMAN
NC score	0.865185 (rank : 3)	θ value	1.08726e-37 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	Q15366, Q6PKG5	Gene names	PCBP2
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (hnRNP-E2).

PCBP2_MOUSE
NC score	0.864804 (rank : 4)	θ value	1.42001e-37 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	47	Shared Neighborhood Hits	30
SwissProt Accessions	Q61990, Q61383, Q62042	Gene names	Pcbp2, Cbp, Hnrnpx, Hnrpx
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP).

PCBP1_HUMAN
NC score	0.859537 (rank : 5)	θ value	1.0531e-32 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q15365, Q13157, Q14975	Gene names	PCBP1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1) (Nucleic acid- binding protein SUB2.3).

PCBP1_MOUSE
NC score	0.859537 (rank : 6)	θ value	1.0531e-32 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	P60335	Gene names	Pcbp1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1).

PCBP4_MOUSE
NC score	0.824960 (rank : 7)	θ value	4.15078e-21 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	P57724, Q91VR3	Gene names	Pcbp4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

PCBP4_HUMAN
NC score	0.822996 (rank : 8)	θ value	7.0802e-21 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	P57723, Q96AH7	Gene names	PCBP4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

PCBP3_MOUSE
NC score	0.816485 (rank : 9)	θ value	1.24977e-17 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	P57722, Q8BSB0, Q8C544	Gene names	Pcbp3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP3_HUMAN
NC score	0.816430 (rank : 10)	θ value	1.24977e-17 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	P57721, Q8N9K6, Q96EP6	Gene names	PCBP3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

NOVA2_HUMAN
NC score	0.722887 (rank : 11)	θ value	4.59992e-12 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UNW9, O43267, Q9UEA1	Gene names	NOVA2, ANOVA, NOVA3
Domain Architecture
Description	RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein).

NOVA1_HUMAN
NC score	0.706332 (rank : 12)	θ value	3.08544e-08 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	50	Shared Neighborhood Hits	32
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

FUBP3_HUMAN
NC score	0.587083 (rank : 13)	θ value	9.92553e-07 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

FUBP2_HUMAN
NC score	0.566644 (rank : 14)	θ value	1.29631e-06 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	145	Shared Neighborhood Hits	32
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

FUBP1_MOUSE
NC score	0.558368 (rank : 15)	θ value	4.45536e-07 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	144	Shared Neighborhood Hits	32
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

FUBP1_HUMAN
NC score	0.557484 (rank : 16)	θ value	4.45536e-07 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	136	Shared Neighborhood Hits	32
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

IF2B2_HUMAN
NC score	0.531099 (rank : 17)	θ value	1.29631e-06 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	142	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

IF2B2_MOUSE
NC score	0.512008 (rank : 18)	θ value	0.000158464 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	148	Shared Neighborhood Hits	32
SwissProt Accessions	Q5SF07, Q3TCU4, Q7TQF9	Gene names	Igf2bp2, Imp2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2).

TDRKH_HUMAN
NC score	0.411653 (rank : 19)	θ value	0.00869519 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	59	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y2W6, Q8N582, Q9NYV5	Gene names	TDRKH, TDRD2
Domain Architecture
Description	Tudor and KH domain-containing protein.

TDRKH_MOUSE
NC score	0.409047 (rank : 20)	θ value	0.00869519 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	59	Shared Neighborhood Hits	30
SwissProt Accessions	Q80VL1	Gene names	Tdrkh
Domain Architecture
Description	Tudor and KH domain-containing protein.

VIGLN_HUMAN
NC score	0.367879 (rank : 21)	θ value	0.000461057 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

VIGLN_MOUSE
NC score	0.367369 (rank : 22)	θ value	0.000461057 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

AKAP1_HUMAN
NC score	0.241076 (rank : 23)	θ value	0.0193708 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	88	Shared Neighborhood Hits	29
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

AKAP1_MOUSE
NC score	0.229765 (rank : 24)	θ value	0.0193708 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	198	Shared Neighborhood Hits	28
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

FXR2_HUMAN
NC score	0.171333 (rank : 25)	θ value	0.0330416 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

FXR1_HUMAN
NC score	0.169149 (rank : 26)	θ value	0.0563607 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	P51114, Q7Z450, Q8N6R8	Gene names	FXR1
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (hFXR1P).

RKHD1_HUMAN
NC score	0.168708 (rank : 27)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	45	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

FXR1_MOUSE
NC score	0.167599 (rank : 28)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	49	Shared Neighborhood Hits	31
SwissProt Accessions	Q61584, Q8VCU4, Q9R1E2, Q9R1E3, Q9R1E4, Q9R1E5, Q9WUA7, Q9WUA8, Q9WUA9	Gene names	Fxr1, Fxr1h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (mFxr1p).

FXR2_MOUSE
NC score	0.130524 (rank : 29)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	66	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

FMR1_HUMAN
NC score	0.118952 (rank : 30)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	Q06787, Q16578, Q99054	Gene names	FMR1
Domain Architecture
Description	Fragile X mental retardation 1 protein (Protein FMR-1) (FMRP).

FMR1_MOUSE
NC score	0.118250 (rank : 31)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	P35922	Gene names	Fmr1, Fmr-1
Domain Architecture
Description	Fragile X mental retardation protein 1 homolog (Protein FMR-1) (FMRP) (mFmr1p).

SAM68_HUMAN
NC score	0.093073 (rank : 32)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	45	Target Neighborhood Hits	68	Shared Neighborhood Hits	20
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

SAM68_MOUSE
NC score	0.090444 (rank : 33)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	45	Target Neighborhood Hits	65	Shared Neighborhood Hits	20
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

DDX53_HUMAN
NC score	0.063357 (rank : 34)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	124	Shared Neighborhood Hits	22
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

ASXL1_HUMAN
NC score	0.055325 (rank : 35)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	260	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

PNPT1_HUMAN
NC score	0.054561 (rank : 36)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	30	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TCS8, Q53SU0, Q68CN1, Q7Z7D1, Q8IWX1, Q96T05, Q9BRU3, Q9BVX0	Gene names	PNPT1, PNPASE
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

PNPT1_MOUSE
NC score	0.050350 (rank : 37)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1R3, Q3UEP9, Q810U7, Q812B3, Q8R2U3, Q9DC52	Gene names	Pnpt1, Pnpase
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

DDX43_HUMAN
NC score	0.048380 (rank : 38)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

PANK1_HUMAN
NC score	0.027899 (rank : 39)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TE04, Q7RTX6, Q7Z495, Q8TBQ8	Gene names	PANK1, PANK
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (hPanK1) (hPanK).

FRM4A_MOUSE
NC score	0.018351 (rank : 40)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

JIP1_HUMAN
NC score	0.016721 (rank : 41)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

DLG5_HUMAN
NC score	0.016061 (rank : 42)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	1088	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

FRM4A_HUMAN
NC score	0.015112 (rank : 43)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

LAP4_HUMAN
NC score	0.009414 (rank : 44)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	608	Shared Neighborhood Hits	4
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

MYO15_HUMAN
NC score	0.006257 (rank : 45)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	671	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

DMBT1_HUMAN
NC score	0.004937 (rank : 46)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	152	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

FER_HUMAN
NC score	-0.001221 (rank : 47)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	1278	Shared Neighborhood Hits	3
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

ZBT17_HUMAN
NC score	-0.001371 (rank : 48)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	925	Shared Neighborhood Hits	3
SwissProt Accessions	Q13105, Q15932, Q5JYB2, Q9NUC9	Gene names	ZBTB17, MIZ1, ZNF151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Myc-interacting zinc finger protein) (Miz-1 protein).