Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : FXR2_MOUSE

For an explanation of this page, click here

FXR2_MOUSE
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FXR1_MOUSE
θ value	0 (rank : 1)	NC score	0.979912 (rank : 3)
Query Neighborhood Hits	66	Target Neighborhood Hits	49	Shared Neighborhood Hits	20
SwissProt Accessions	Q61584, Q8VCU4, Q9R1E2, Q9R1E3, Q9R1E4, Q9R1E5, Q9WUA7, Q9WUA8, Q9WUA9	Gene names	Fxr1, Fxr1h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (mFxr1p).

FXR2_HUMAN
θ value	0 (rank : 2)	NC score	0.990533 (rank : 2)
Query Neighborhood Hits	66	Target Neighborhood Hits	77	Shared Neighborhood Hits	40
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

FXR2_MOUSE
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	66	Target Neighborhood Hits	66	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

FXR1_HUMAN
θ value	6.5317e-184 (rank : 4)	NC score	0.978187 (rank : 4)
Query Neighborhood Hits	66	Target Neighborhood Hits	50	Shared Neighborhood Hits	19
SwissProt Accessions	P51114, Q7Z450, Q8N6R8	Gene names	FXR1
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (hFXR1P).

FMR1_MOUSE
θ value	2.20485e-131 (rank : 5)	NC score	0.961355 (rank : 6)
Query Neighborhood Hits	66	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	P35922	Gene names	Fmr1, Fmr-1
Domain Architecture
Description	Fragile X mental retardation protein 1 homolog (Protein FMR-1) (FMRP) (mFmr1p).

FMR1_HUMAN
θ value	1.09426e-130 (rank : 6)	NC score	0.962026 (rank : 5)
Query Neighborhood Hits	66	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	Q06787, Q16578, Q99054	Gene names	FMR1
Domain Architecture
Description	Fragile X mental retardation 1 protein (Protein FMR-1) (FMRP).

NPBL_MOUSE
θ value	9.29e-05 (rank : 7)	NC score	0.076082 (rank : 17)
Query Neighborhood Hits	66	Target Neighborhood Hits	1041	Shared Neighborhood Hits	21
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

RGS3_HUMAN
θ value	0.00390308 (rank : 8)	NC score	0.036285 (rank : 32)
Query Neighborhood Hits	66	Target Neighborhood Hits	1375	Shared Neighborhood Hits	16
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TDRKH_HUMAN
θ value	0.00390308 (rank : 9)	NC score	0.203263 (rank : 7)
Query Neighborhood Hits	66	Target Neighborhood Hits	59	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2W6, Q8N582, Q9NYV5	Gene names	TDRKH, TDRD2
Domain Architecture
Description	Tudor and KH domain-containing protein.

TDRKH_MOUSE
θ value	0.00390308 (rank : 10)	NC score	0.200466 (rank : 8)
Query Neighborhood Hits	66	Target Neighborhood Hits	59	Shared Neighborhood Hits	17
SwissProt Accessions	Q80VL1	Gene names	Tdrkh
Domain Architecture
Description	Tudor and KH domain-containing protein.

HNRPK_HUMAN
θ value	0.0736092 (rank : 11)	NC score	0.130524 (rank : 9)
Query Neighborhood Hits	66	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	P61978, Q07244, Q15671, Q60577, Q922Y7, Q96J62	Gene names	HNRPK, HNRNPK
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP).

HNRPK_MOUSE
θ value	0.0736092 (rank : 12)	NC score	0.130524 (rank : 10)
Query Neighborhood Hits	66	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	P61979, Q07244, Q15671, Q60577, Q8BGQ8, Q922Y7, Q96J62	Gene names	Hnrpk, Hnrnpk
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K.

BRE1B_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.017749 (rank : 44)
Query Neighborhood Hits	66	Target Neighborhood Hits	1040	Shared Neighborhood Hits	11
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

LAP2B_HUMAN
θ value	0.279714 (rank : 14)	NC score	0.049033 (rank : 30)
Query Neighborhood Hits	66	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	P42167, Q14861	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2, isoforms beta/gamma (Thymopoietin, isoforms beta/gamma) (TP beta/gamma) (Thymopoietin-related peptide isoforms beta/gamma) (TPRP isoforms beta/gamma) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

NIPBL_HUMAN
θ value	0.365318 (rank : 15)	NC score	0.065512 (rank : 20)
Query Neighborhood Hits	66	Target Neighborhood Hits	1311	Shared Neighborhood Hits	23
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

RPTN_MOUSE
θ value	0.47712 (rank : 16)	NC score	0.035015 (rank : 33)
Query Neighborhood Hits	66	Target Neighborhood Hits	650	Shared Neighborhood Hits	13
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

MYH6_HUMAN
θ value	0.62314 (rank : 17)	NC score	0.013810 (rank : 48)
Query Neighborhood Hits	66	Target Neighborhood Hits	1426	Shared Neighborhood Hits	11
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

PCLO_MOUSE
θ value	0.62314 (rank : 18)	NC score	0.017294 (rank : 45)
Query Neighborhood Hits	66	Target Neighborhood Hits	2275	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CSPG3_MOUSE
θ value	0.813845 (rank : 19)	NC score	0.010821 (rank : 56)
Query Neighborhood Hits	66	Target Neighborhood Hits	657	Shared Neighborhood Hits	8
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

MYH6_MOUSE
θ value	0.813845 (rank : 20)	NC score	0.013496 (rank : 49)
Query Neighborhood Hits	66	Target Neighborhood Hits	1501	Shared Neighborhood Hits	11
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

PNPT1_HUMAN
θ value	0.813845 (rank : 21)	NC score	0.064733 (rank : 21)
Query Neighborhood Hits	66	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TCS8, Q53SU0, Q68CN1, Q7Z7D1, Q8IWX1, Q96T05, Q9BRU3, Q9BVX0	Gene names	PNPT1, PNPASE
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

MINT_MOUSE
θ value	1.06291 (rank : 22)	NC score	0.025464 (rank : 35)
Query Neighborhood Hits	66	Target Neighborhood Hits	1514	Shared Neighborhood Hits	27
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SRBS1_MOUSE
θ value	1.06291 (rank : 23)	NC score	0.022976 (rank : 39)
Query Neighborhood Hits	66	Target Neighborhood Hits	409	Shared Neighborhood Hits	7
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

TNK1_HUMAN
θ value	1.06291 (rank : 24)	NC score	0.005884 (rank : 71)
Query Neighborhood Hits	66	Target Neighborhood Hits	815	Shared Neighborhood Hits	5
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

BMP3B_MOUSE
θ value	1.81305 (rank : 25)	NC score	0.010526 (rank : 59)
Query Neighborhood Hits	66	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	P97737	Gene names	Gdf10, Bmp3b
Domain Architecture
Description	Bone morphogenetic protein 3b precursor (BMP-3b) (Growth/differentiation factor 10) (GDF-10).

HMMR_MOUSE
θ value	1.81305 (rank : 26)	NC score	0.012387 (rank : 54)
Query Neighborhood Hits	66	Target Neighborhood Hits	1178	Shared Neighborhood Hits	14
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

MLL3_HUMAN
θ value	1.81305 (rank : 27)	NC score	0.012735 (rank : 50)
Query Neighborhood Hits	66	Target Neighborhood Hits	1644	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

WWP2_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.007899 (rank : 66)
Query Neighborhood Hits	66	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

CJ026_MOUSE
θ value	2.36792 (rank : 29)	NC score	0.023134 (rank : 38)
Query Neighborhood Hits	66	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGW2, Q3TF48, Q3U3M2, Q6PD43, Q8R0W8	Gene names	D19Wsu162e
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf26 homolog.

MYH7_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.012087 (rank : 55)
Query Neighborhood Hits	66	Target Neighborhood Hits	1559	Shared Neighborhood Hits	14
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

PNPT1_MOUSE
θ value	2.36792 (rank : 31)	NC score	0.045659 (rank : 31)
Query Neighborhood Hits	66	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K1R3, Q3UEP9, Q810U7, Q812B3, Q8R2U3, Q9DC52	Gene names	Pnpt1, Pnpase
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

RGS3_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.021629 (rank : 40)
Query Neighborhood Hits	66	Target Neighborhood Hits	1621	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RNF6_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.016322 (rank : 46)
Query Neighborhood Hits	66	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

AL2S4_MOUSE
θ value	3.0926 (rank : 34)	NC score	0.029279 (rank : 34)
Query Neighborhood Hits	66	Target Neighborhood Hits	193	Shared Neighborhood Hits	6
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

FUBP2_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.110971 (rank : 12)
Query Neighborhood Hits	66	Target Neighborhood Hits	145	Shared Neighborhood Hits	21
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

PAK4_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.000337 (rank : 75)
Query Neighborhood Hits	66	Target Neighborhood Hits	1098	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

RBM15_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.023742 (rank : 37)
Query Neighborhood Hits	66	Target Neighborhood Hits	309	Shared Neighborhood Hits	10
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

AMOL2_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.012599 (rank : 52)
Query Neighborhood Hits	66	Target Neighborhood Hits	603	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

FMN1B_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.021312 (rank : 41)
Query Neighborhood Hits	66	Target Neighborhood Hits	447	Shared Neighborhood Hits	16
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

PCBP3_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.068711 (rank : 19)
Query Neighborhood Hits	66	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	P57721, Q8N9K6, Q96EP6	Gene names	PCBP3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP3_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.068726 (rank : 18)
Query Neighborhood Hits	66	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	P57722, Q8BSB0, Q8C544	Gene names	Pcbp3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PTN13_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.006842 (rank : 69)
Query Neighborhood Hits	66	Target Neighborhood Hits	426	Shared Neighborhood Hits	7
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

SPEG_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.002556 (rank : 74)
Query Neighborhood Hits	66	Target Neighborhood Hits	1762	Shared Neighborhood Hits	18
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TEP1_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.010053 (rank : 61)
Query Neighborhood Hits	66	Target Neighborhood Hits	344	Shared Neighborhood Hits	4
SwissProt Accessions	P97499	Gene names	Tep1, Tp1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 homolog).

VSX1_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.008004 (rank : 65)
Query Neighborhood Hits	66	Target Neighborhood Hits	356	Shared Neighborhood Hits	3
SwissProt Accessions	Q91V10	Gene names	Vsx1, Rinx
Domain Architecture
Description	Visual system homeobox 1 (Transcription factor VSX1) (Retinal inner nuclear layer homeobox protein) (Homeodomain protein RINX).

COA2_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.012687 (rank : 51)
Query Neighborhood Hits	66	Target Neighborhood Hits	184	Shared Neighborhood Hits	6
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

ESCO1_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.012445 (rank : 53)
Query Neighborhood Hits	66	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q69Z69, Q8BQI2, Q8BR47, Q922F5	Gene names	Esco1, Kiaa1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1).

IWS1_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.015020 (rank : 47)
Query Neighborhood Hits	66	Target Neighborhood Hits	1258	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RRBP1_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.019501 (rank : 43)
Query Neighborhood Hits	66	Target Neighborhood Hits	1650	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

TTC1_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.007460 (rank : 68)
Query Neighborhood Hits	66	Target Neighborhood Hits	417	Shared Neighborhood Hits	4
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

CT043_MOUSE
θ value	6.88961 (rank : 51)	NC score	0.020760 (rank : 42)
Query Neighborhood Hits	66	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q99K95, Q543D3, Q80X88, Q9CV27	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf43 homolog.

EVL_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.009454 (rank : 62)
Query Neighborhood Hits	66	Target Neighborhood Hits	260	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

MBD1_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.010326 (rank : 60)
Query Neighborhood Hits	66	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

PCBP2_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.054537 (rank : 25)
Query Neighborhood Hits	66	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	Q15366, Q6PKG5	Gene names	PCBP2
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (hnRNP-E2).

PCBP2_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.054409 (rank : 26)
Query Neighborhood Hits	66	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	Q61990, Q61383, Q62042	Gene names	Pcbp2, Cbp, Hnrnpx, Hnrpx
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP).

S39A6_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.024273 (rank : 36)
Query Neighborhood Hits	66	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C145, Q7TPP9, Q7TQE0, Q8R518	Gene names	Slc39a6
Domain Architecture	No domain graphic available
Description	Zinc transporter SLC39A6 precursor (Solute carrier family 39 member 6) (Endoplasmic reticulum membrane-linked protein) (Ermelin).

DUS5_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.004123 (rank : 73)
Query Neighborhood Hits	66	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

FUBP1_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.107352 (rank : 14)
Query Neighborhood Hits	66	Target Neighborhood Hits	136	Shared Neighborhood Hits	20
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

FUBP1_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.108000 (rank : 13)
Query Neighborhood Hits	66	Target Neighborhood Hits	144	Shared Neighborhood Hits	21
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

HTF4_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.005947 (rank : 70)
Query Neighborhood Hits	66	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

MDM2_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.010697 (rank : 58)
Query Neighborhood Hits	66	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

NCOA3_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.007704 (rank : 67)
Query Neighborhood Hits	66	Target Neighborhood Hits	171	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

PEX14_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.010781 (rank : 57)
Query Neighborhood Hits	66	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	O75381, Q8WX51	Gene names	PEX14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

SFRS2_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.009138 (rank : 63)
Query Neighborhood Hits	66	Target Neighborhood Hits	222	Shared Neighborhood Hits	7
SwissProt Accessions	Q01130	Gene names	SFRS2
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264).

SFRS2_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.009138 (rank : 64)
Query Neighborhood Hits	66	Target Neighborhood Hits	222	Shared Neighborhood Hits	7
SwissProt Accessions	Q62093, Q542L3, Q60701	Gene names	Sfrs2, Pr264, Sfrs10
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264) (Putative myelin regulatory factor 1) (MRF-1).

TCF7_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.005233 (rank : 72)
Query Neighborhood Hits	66	Target Neighborhood Hits	277	Shared Neighborhood Hits	4
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

FUBP3_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.114424 (rank : 11)
Query Neighborhood Hits	66	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

IF2B2_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.055895 (rank : 22)
Query Neighborhood Hits	66	Target Neighborhood Hits	142	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

IF2B2_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.055357 (rank : 23)
Query Neighborhood Hits	66	Target Neighborhood Hits	148	Shared Neighborhood Hits	21
SwissProt Accessions	Q5SF07, Q3TCU4, Q7TQF9	Gene names	Igf2bp2, Imp2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2).

NOVA1_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.095385 (rank : 15)
Query Neighborhood Hits	66	Target Neighborhood Hits	50	Shared Neighborhood Hits	18
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

NOVA2_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.092285 (rank : 16)
Query Neighborhood Hits	66	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UNW9, O43267, Q9UEA1	Gene names	NOVA2, ANOVA, NOVA3
Domain Architecture
Description	RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein).

PCBP1_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.050160 (rank : 28)
Query Neighborhood Hits	66	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	Q15365, Q13157, Q14975	Gene names	PCBP1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1) (Nucleic acid- binding protein SUB2.3).

PCBP1_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.050160 (rank : 29)
Query Neighborhood Hits	66	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	P60335	Gene names	Pcbp1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1).

VIGLN_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.052187 (rank : 27)
Query Neighborhood Hits	66	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

VIGLN_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.054654 (rank : 24)
Query Neighborhood Hits	66	Target Neighborhood Hits	80	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

Hits sorted by NC score

FXR2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	66	Target Neighborhood Hits	66	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

FXR2_HUMAN
NC score	0.990533 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	66	Target Neighborhood Hits	77	Shared Neighborhood Hits	40
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

FXR1_MOUSE
NC score	0.979912 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	66	Target Neighborhood Hits	49	Shared Neighborhood Hits	20
SwissProt Accessions	Q61584, Q8VCU4, Q9R1E2, Q9R1E3, Q9R1E4, Q9R1E5, Q9WUA7, Q9WUA8, Q9WUA9	Gene names	Fxr1, Fxr1h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (mFxr1p).

FXR1_HUMAN
NC score	0.978187 (rank : 4)	θ value	6.5317e-184 (rank : 4)
Query Neighborhood Hits	66	Target Neighborhood Hits	50	Shared Neighborhood Hits	19
SwissProt Accessions	P51114, Q7Z450, Q8N6R8	Gene names	FXR1
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (hFXR1P).

FMR1_HUMAN
NC score	0.962026 (rank : 5)	θ value	1.09426e-130 (rank : 6)
Query Neighborhood Hits	66	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	Q06787, Q16578, Q99054	Gene names	FMR1
Domain Architecture
Description	Fragile X mental retardation 1 protein (Protein FMR-1) (FMRP).

FMR1_MOUSE
NC score	0.961355 (rank : 6)	θ value	2.20485e-131 (rank : 5)
Query Neighborhood Hits	66	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	P35922	Gene names	Fmr1, Fmr-1
Domain Architecture
Description	Fragile X mental retardation protein 1 homolog (Protein FMR-1) (FMRP) (mFmr1p).

TDRKH_HUMAN
NC score	0.203263 (rank : 7)	θ value	0.00390308 (rank : 9)
Query Neighborhood Hits	66	Target Neighborhood Hits	59	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2W6, Q8N582, Q9NYV5	Gene names	TDRKH, TDRD2
Domain Architecture
Description	Tudor and KH domain-containing protein.

TDRKH_MOUSE
NC score	0.200466 (rank : 8)	θ value	0.00390308 (rank : 10)
Query Neighborhood Hits	66	Target Neighborhood Hits	59	Shared Neighborhood Hits	17
SwissProt Accessions	Q80VL1	Gene names	Tdrkh
Domain Architecture
Description	Tudor and KH domain-containing protein.

HNRPK_HUMAN
NC score	0.130524 (rank : 9)	θ value	0.0736092 (rank : 11)
Query Neighborhood Hits	66	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	P61978, Q07244, Q15671, Q60577, Q922Y7, Q96J62	Gene names	HNRPK, HNRNPK
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP).

HNRPK_MOUSE
NC score	0.130524 (rank : 10)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	66	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	P61979, Q07244, Q15671, Q60577, Q8BGQ8, Q922Y7, Q96J62	Gene names	Hnrpk, Hnrnpk
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein K.

FUBP3_HUMAN
NC score	0.114424 (rank : 11)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	66	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

FUBP2_HUMAN
NC score	0.110971 (rank : 12)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	66	Target Neighborhood Hits	145	Shared Neighborhood Hits	21
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

FUBP1_MOUSE
NC score	0.108000 (rank : 13)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	66	Target Neighborhood Hits	144	Shared Neighborhood Hits	21
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

FUBP1_HUMAN
NC score	0.107352 (rank : 14)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	66	Target Neighborhood Hits	136	Shared Neighborhood Hits	20
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

NOVA1_HUMAN
NC score	0.095385 (rank : 15)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	66	Target Neighborhood Hits	50	Shared Neighborhood Hits	18
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

NOVA2_HUMAN
NC score	0.092285 (rank : 16)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	66	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UNW9, O43267, Q9UEA1	Gene names	NOVA2, ANOVA, NOVA3
Domain Architecture
Description	RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein).

NPBL_MOUSE
NC score	0.076082 (rank : 17)	θ value	9.29e-05 (rank : 7)
Query Neighborhood Hits	66	Target Neighborhood Hits	1041	Shared Neighborhood Hits	21
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PCBP3_MOUSE
NC score	0.068726 (rank : 18)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	66	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	P57722, Q8BSB0, Q8C544	Gene names	Pcbp3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

PCBP3_HUMAN
NC score	0.068711 (rank : 19)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	66	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	P57721, Q8N9K6, Q96EP6	Gene names	PCBP3
Domain Architecture
Description	Poly(rC)-binding protein 3 (Alpha-CP3).

NIPBL_HUMAN
NC score	0.065512 (rank : 20)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	66	Target Neighborhood Hits	1311	Shared Neighborhood Hits	23
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PNPT1_HUMAN
NC score	0.064733 (rank : 21)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	66	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TCS8, Q53SU0, Q68CN1, Q7Z7D1, Q8IWX1, Q96T05, Q9BRU3, Q9BVX0	Gene names	PNPT1, PNPASE
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

IF2B2_HUMAN
NC score	0.055895 (rank : 22)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	66	Target Neighborhood Hits	142	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

IF2B2_MOUSE
NC score	0.055357 (rank : 23)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	66	Target Neighborhood Hits	148	Shared Neighborhood Hits	21
SwissProt Accessions	Q5SF07, Q3TCU4, Q7TQF9	Gene names	Igf2bp2, Imp2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2).

VIGLN_MOUSE
NC score	0.054654 (rank : 24)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	66	Target Neighborhood Hits	80	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VDJ3	Gene names	Hdlbp
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

PCBP2_HUMAN
NC score	0.054537 (rank : 25)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	66	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	Q15366, Q6PKG5	Gene names	PCBP2
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (hnRNP-E2).

PCBP2_MOUSE
NC score	0.054409 (rank : 26)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	66	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	Q61990, Q61383, Q62042	Gene names	Pcbp2, Cbp, Hnrnpx, Hnrpx
Domain Architecture
Description	Poly(rC)-binding protein 2 (Alpha-CP2) (Putative heterogeneous nuclear ribonucleoprotein X) (hnRNP X) (CTBP) (CBP).

VIGLN_HUMAN
NC score	0.052187 (rank : 27)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	66	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	Q00341, Q9UCY3	Gene names	HDLBP, HBP, VGL
Domain Architecture
Description	Vigilin (High density lipoprotein-binding protein) (HDL-binding protein).

PCBP1_HUMAN
NC score	0.050160 (rank : 28)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	66	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	Q15365, Q13157, Q14975	Gene names	PCBP1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1) (Nucleic acid- binding protein SUB2.3).

PCBP1_MOUSE
NC score	0.050160 (rank : 29)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	66	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	P60335	Gene names	Pcbp1
Domain Architecture
Description	Poly(rC)-binding protein 1 (Alpha-CP1) (hnRNP-E1).

LAP2B_HUMAN
NC score	0.049033 (rank : 30)	θ value	0.279714 (rank : 14)
Query Neighborhood Hits	66	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	P42167, Q14861	Gene names	TMPO, LAP2
Domain Architecture
Description	Lamina-associated polypeptide 2, isoforms beta/gamma (Thymopoietin, isoforms beta/gamma) (TP beta/gamma) (Thymopoietin-related peptide isoforms beta/gamma) (TPRP isoforms beta/gamma) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].

PNPT1_MOUSE
NC score	0.045659 (rank : 31)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	66	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K1R3, Q3UEP9, Q810U7, Q812B3, Q8R2U3, Q9DC52	Gene names	Pnpt1, Pnpase
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

RGS3_HUMAN
NC score	0.036285 (rank : 32)	θ value	0.00390308 (rank : 8)
Query Neighborhood Hits	66	Target Neighborhood Hits	1375	Shared Neighborhood Hits	16
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RPTN_MOUSE
NC score	0.035015 (rank : 33)	θ value	0.47712 (rank : 16)
Query Neighborhood Hits	66	Target Neighborhood Hits	650	Shared Neighborhood Hits	13
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

AL2S4_MOUSE
NC score	0.029279 (rank : 34)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	66	Target Neighborhood Hits	193	Shared Neighborhood Hits	6
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

MINT_MOUSE
NC score	0.025464 (rank : 35)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	66	Target Neighborhood Hits	1514	Shared Neighborhood Hits	27
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

S39A6_MOUSE
NC score	0.024273 (rank : 36)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	66	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C145, Q7TPP9, Q7TQE0, Q8R518	Gene names	Slc39a6
Domain Architecture	No domain graphic available
Description	Zinc transporter SLC39A6 precursor (Solute carrier family 39 member 6) (Endoplasmic reticulum membrane-linked protein) (Ermelin).

RBM15_HUMAN
NC score	0.023742 (rank : 37)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	66	Target Neighborhood Hits	309	Shared Neighborhood Hits	10
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

CJ026_MOUSE
NC score	0.023134 (rank : 38)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	66	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGW2, Q3TF48, Q3U3M2, Q6PD43, Q8R0W8	Gene names	D19Wsu162e
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf26 homolog.

SRBS1_MOUSE
NC score	0.022976 (rank : 39)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	66	Target Neighborhood Hits	409	Shared Neighborhood Hits	7
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

RGS3_MOUSE
NC score	0.021629 (rank : 40)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	66	Target Neighborhood Hits	1621	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

FMN1B_MOUSE
NC score	0.021312 (rank : 41)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	66	Target Neighborhood Hits	447	Shared Neighborhood Hits	16
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

CT043_MOUSE
NC score	0.020760 (rank : 42)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	66	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q99K95, Q543D3, Q80X88, Q9CV27	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf43 homolog.

RRBP1_MOUSE
NC score	0.019501 (rank : 43)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	66	Target Neighborhood Hits	1650	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

BRE1B_HUMAN
NC score	0.017749 (rank : 44)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	66	Target Neighborhood Hits	1040	Shared Neighborhood Hits	11
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

PCLO_MOUSE
NC score	0.017294 (rank : 45)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	66	Target Neighborhood Hits	2275	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RNF6_HUMAN
NC score	0.016322 (rank : 46)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	66	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

IWS1_MOUSE
NC score	0.015020 (rank : 47)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	66	Target Neighborhood Hits	1258	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MYH6_HUMAN
NC score	0.013810 (rank : 48)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	66	Target Neighborhood Hits	1426	Shared Neighborhood Hits	11
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_MOUSE
NC score	0.013496 (rank : 49)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	66	Target Neighborhood Hits	1501	Shared Neighborhood Hits	11
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MLL3_HUMAN
NC score	0.012735 (rank : 50)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	66	Target Neighborhood Hits	1644	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

COA2_HUMAN
NC score	0.012687 (rank : 51)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	66	Target Neighborhood Hits	184	Shared Neighborhood Hits	6
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

AMOL2_HUMAN
NC score	0.012599 (rank : 52)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	66	Target Neighborhood Hits	603	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

ESCO1_MOUSE
NC score	0.012445 (rank : 53)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	66	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q69Z69, Q8BQI2, Q8BR47, Q922F5	Gene names	Esco1, Kiaa1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1).

HMMR_MOUSE
NC score	0.012387 (rank : 54)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	66	Target Neighborhood Hits	1178	Shared Neighborhood Hits	14
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

MYH7_HUMAN
NC score	0.012087 (rank : 55)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	66	Target Neighborhood Hits	1559	Shared Neighborhood Hits	14
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

CSPG3_MOUSE
NC score	0.010821 (rank : 56)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	66	Target Neighborhood Hits	657	Shared Neighborhood Hits	8
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

PEX14_HUMAN
NC score	0.010781 (rank : 57)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	66	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	O75381, Q8WX51	Gene names	PEX14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

MDM2_HUMAN
NC score	0.010697 (rank : 58)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	66	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

BMP3B_MOUSE
NC score	0.010526 (rank : 59)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	66	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	P97737	Gene names	Gdf10, Bmp3b
Domain Architecture
Description	Bone morphogenetic protein 3b precursor (BMP-3b) (Growth/differentiation factor 10) (GDF-10).

MBD1_HUMAN
NC score	0.010326 (rank : 60)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	66	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

TEP1_MOUSE
NC score	0.010053 (rank : 61)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	66	Target Neighborhood Hits	344	Shared Neighborhood Hits	4
SwissProt Accessions	P97499	Gene names	Tep1, Tp1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 homolog).

EVL_HUMAN
NC score	0.009454 (rank : 62)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	66	Target Neighborhood Hits	260	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

SFRS2_HUMAN
NC score	0.009138 (rank : 63)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	66	Target Neighborhood Hits	222	Shared Neighborhood Hits	7
SwissProt Accessions	Q01130	Gene names	SFRS2
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264).

SFRS2_MOUSE
NC score	0.009138 (rank : 64)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	66	Target Neighborhood Hits	222	Shared Neighborhood Hits	7
SwissProt Accessions	Q62093, Q542L3, Q60701	Gene names	Sfrs2, Pr264, Sfrs10
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264) (Putative myelin regulatory factor 1) (MRF-1).

VSX1_MOUSE
NC score	0.008004 (rank : 65)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	66	Target Neighborhood Hits	356	Shared Neighborhood Hits	3
SwissProt Accessions	Q91V10	Gene names	Vsx1, Rinx
Domain Architecture
Description	Visual system homeobox 1 (Transcription factor VSX1) (Retinal inner nuclear layer homeobox protein) (Homeodomain protein RINX).

WWP2_HUMAN
NC score	0.007899 (rank : 66)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	66	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

NCOA3_HUMAN
NC score	0.007704 (rank : 67)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	66	Target Neighborhood Hits	171	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

TTC1_HUMAN
NC score	0.007460 (rank : 68)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	66	Target Neighborhood Hits	417	Shared Neighborhood Hits	4
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

PTN13_MOUSE
NC score	0.006842 (rank : 69)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	66	Target Neighborhood Hits	426	Shared Neighborhood Hits	7
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

HTF4_MOUSE
NC score	0.005947 (rank : 70)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	66	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

TNK1_HUMAN
NC score	0.005884 (rank : 71)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	66	Target Neighborhood Hits	815	Shared Neighborhood Hits	5
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

TCF7_MOUSE
NC score	0.005233 (rank : 72)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	66	Target Neighborhood Hits	277	Shared Neighborhood Hits	4
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

DUS5_HUMAN
NC score	0.004123 (rank : 73)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	66	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

SPEG_HUMAN
NC score	0.002556 (rank : 74)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	66	Target Neighborhood Hits	1762	Shared Neighborhood Hits	18
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

PAK4_MOUSE
NC score	0.000337 (rank : 75)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	66	Target Neighborhood Hits	1098	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).