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Network neighborhood for query Sequence : S39A6_MOUSE

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S39A6_MOUSE
SwissProt Accessions	Q8C145, Q7TPP9, Q7TQE0, Q8R518	Gene names	Slc39a6
Domain Architecture	No domain graphic available
Description	Zinc transporter SLC39A6 precursor (Solute carrier family 39 member 6) (Endoplasmic reticulum membrane-linked protein) (Ermelin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

S39A6_HUMAN
θ value	0 (rank : 1)	NC score	0.991425 (rank : 2)
Query Neighborhood Hits	48	Target Neighborhood Hits	31	Shared Neighborhood Hits	20
SwissProt Accessions	Q13433, Q8IXR3, Q96HP5	Gene names	SLC39A6, LIV1
Domain Architecture	No domain graphic available
Description	Zinc transporter SLC39A6 precursor (Solute carrier family 39 member 6) (Estrogen-regulated protein LIV-1).

S39A6_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	48
SwissProt Accessions	Q8C145, Q7TPP9, Q7TQE0, Q8R518	Gene names	Slc39a6
Domain Architecture	No domain graphic available
Description	Zinc transporter SLC39A6 precursor (Solute carrier family 39 member 6) (Endoplasmic reticulum membrane-linked protein) (Ermelin).

S39A5_HUMAN
θ value	3.61944e-33 (rank : 3)	NC score	0.824270 (rank : 3)
Query Neighborhood Hits	48	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZMH5, Q8N6Y3	Gene names	SLC39A5, ZIP5
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP5 precursor (Solute carrier family 39 member 5).

S39A5_MOUSE
θ value	2.34606e-32 (rank : 4)	NC score	0.810863 (rank : 4)
Query Neighborhood Hits	48	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D856, Q9D909	Gene names	Slc39a5, Zip5
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP5 precursor (Solute carrier family 39 member 5).

S39A4_HUMAN
θ value	5.22648e-32 (rank : 5)	NC score	0.797511 (rank : 5)
Query Neighborhood Hits	48	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P5W5, Q7L5S5, Q9H6T8, Q9NXC4	Gene names	SLC39A4, ZIP4
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP4 precursor (Solute carrier family 39 member 4).

S39A4_MOUSE
θ value	1.16434e-31 (rank : 6)	NC score	0.789830 (rank : 6)
Query Neighborhood Hits	48	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q78IQ7, Q8CHL4	Gene names	Slc39a4, Zip4
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP4 precursor (Solute carrier family 39 member 4) (Activated in W/Wv mouse stomach 2) (mAWMS2).

KE4_HUMAN
θ value	5.07402e-19 (rank : 7)	NC score	0.739592 (rank : 7)
Query Neighborhood Hits	48	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q92504, Q5STP8, Q9UIQ0	Gene names	SLC39A7, HKE4, RING5
Domain Architecture
Description	Zinc transporter SLC39A7 (Solute carrier family 39 member 7) (Histidine-rich membrane protein Ke4).

KE4_MOUSE
θ value	1.47631e-18 (rank : 8)	NC score	0.733958 (rank : 8)
Query Neighborhood Hits	48	Target Neighborhood Hits	29	Shared Neighborhood Hits	16
SwissProt Accessions	Q31125, Q3TVU6, Q9Z1W1	Gene names	Slc39a7, H2-Ke4, Hke4
Domain Architecture
Description	Zinc transporter SLC39A7 (Solute carrier family 39 member 7) (Histidine-rich membrane protein Ke4).

NELFA_HUMAN
θ value	0.0736092 (rank : 9)	NC score	0.074855 (rank : 10)
Query Neighborhood Hits	48	Target Neighborhood Hits	161	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

S39A2_HUMAN
θ value	0.0736092 (rank : 10)	NC score	0.170671 (rank : 9)
Query Neighborhood Hits	48	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NP94, Q96JT6	Gene names	SLC39A2, ZIP2
Domain Architecture
Description	Zinc transporter ZIP2 (Eti-1) (6A1) (hZIP2) (Solute carrier family 39 member 2).

ELOA1_HUMAN
θ value	0.21417 (rank : 11)	NC score	0.040210 (rank : 19)
Query Neighborhood Hits	48	Target Neighborhood Hits	388	Shared Neighborhood Hits	17
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

LEO1_MOUSE
θ value	0.365318 (rank : 12)	NC score	0.048419 (rank : 18)
Query Neighborhood Hits	48	Target Neighborhood Hits	946	Shared Neighborhood Hits	17
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

CHD1_HUMAN
θ value	0.62314 (rank : 13)	NC score	0.027372 (rank : 28)
Query Neighborhood Hits	48	Target Neighborhood Hits	337	Shared Neighborhood Hits	15
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

NELFA_MOUSE
θ value	0.62314 (rank : 14)	NC score	0.064489 (rank : 11)
Query Neighborhood Hits	48	Target Neighborhood Hits	195	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

CDC5L_MOUSE
θ value	0.813845 (rank : 15)	NC score	0.039660 (rank : 20)
Query Neighborhood Hits	48	Target Neighborhood Hits	205	Shared Neighborhood Hits	4
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

LEO1_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.052544 (rank : 15)
Query Neighborhood Hits	48	Target Neighborhood Hits	958	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

FATH_HUMAN
θ value	1.81305 (rank : 17)	NC score	0.004635 (rank : 46)
Query Neighborhood Hits	48	Target Neighborhood Hits	570	Shared Neighborhood Hits	2
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

MDC1_HUMAN
θ value	1.81305 (rank : 18)	NC score	0.014228 (rank : 40)
Query Neighborhood Hits	48	Target Neighborhood Hits	1446	Shared Neighborhood Hits	11
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PARP2_MOUSE
θ value	1.81305 (rank : 19)	NC score	0.021797 (rank : 33)
Query Neighborhood Hits	48	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

CHD1_MOUSE
θ value	2.36792 (rank : 20)	NC score	0.020936 (rank : 35)
Query Neighborhood Hits	48	Target Neighborhood Hits	266	Shared Neighborhood Hits	11
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

RLF_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.005944 (rank : 44)
Query Neighborhood Hits	48	Target Neighborhood Hits	775	Shared Neighborhood Hits	5
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

SH3K1_MOUSE
θ value	2.36792 (rank : 22)	NC score	0.018543 (rank : 36)
Query Neighborhood Hits	48	Target Neighborhood Hits	332	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SRCH_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.057653 (rank : 13)
Query Neighborhood Hits	48	Target Neighborhood Hits	225	Shared Neighborhood Hits	18
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

TUB_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.016757 (rank : 38)
Query Neighborhood Hits	48	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P50607, O00293	Gene names	TUB
Domain Architecture
Description	Tubby protein homolog.

CCD55_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.035249 (rank : 22)
Query Neighborhood Hits	48	Target Neighborhood Hits	513	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

PEG3_MOUSE
θ value	3.0926 (rank : 26)	NC score	0.007449 (rank : 43)
Query Neighborhood Hits	48	Target Neighborhood Hits	1101	Shared Neighborhood Hits	18
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

PPIG_HUMAN
θ value	3.0926 (rank : 27)	NC score	0.016488 (rank : 39)
Query Neighborhood Hits	48	Target Neighborhood Hits	670	Shared Neighborhood Hits	16
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

RPTN_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.035794 (rank : 21)
Query Neighborhood Hits	48	Target Neighborhood Hits	406	Shared Neighborhood Hits	16
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

SH3K1_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.017222 (rank : 37)
Query Neighborhood Hits	48	Target Neighborhood Hits	341	Shared Neighborhood Hits	3
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

STC2_MOUSE
θ value	3.0926 (rank : 30)	NC score	0.032722 (rank : 24)
Query Neighborhood Hits	48	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	O88452	Gene names	Stc2
Domain Architecture
Description	Stanniocalcin-2 precursor (STC-2).

BICD1_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.005323 (rank : 45)
Query Neighborhood Hits	48	Target Neighborhood Hits	844	Shared Neighborhood Hits	3
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CDC5L_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.032823 (rank : 23)
Query Neighborhood Hits	48	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q99459, Q76N46, Q99974	Gene names	CDC5L, KIAA0432, PCDC5RP
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5- related protein).

RPTN_MOUSE
θ value	4.03905 (rank : 33)	NC score	0.030507 (rank : 26)
Query Neighborhood Hits	48	Target Neighborhood Hits	650	Shared Neighborhood Hits	21
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

STC2_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.030847 (rank : 25)
Query Neighborhood Hits	48	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	O76061	Gene names	STC2
Domain Architecture
Description	Stanniocalcin-2 precursor (STC-2) (Stanniocalcin-related protein) (STCRP) (STC-related protein).

CCD55_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.051086 (rank : 16)
Query Neighborhood Hits	48	Target Neighborhood Hits	519	Shared Neighborhood Hits	19
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

FILA_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.050868 (rank : 17)
Query Neighborhood Hits	48	Target Neighborhood Hits	685	Shared Neighborhood Hits	19
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

FXR1_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.024987 (rank : 29)
Query Neighborhood Hits	48	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	P51114, Q7Z450, Q8N6R8	Gene names	FXR1
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (hFXR1P).

FXR1_MOUSE
θ value	5.27518 (rank : 38)	NC score	0.024945 (rank : 30)
Query Neighborhood Hits	48	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q61584, Q8VCU4, Q9R1E2, Q9R1E3, Q9R1E4, Q9R1E5, Q9WUA7, Q9WUA8, Q9WUA9	Gene names	Fxr1, Fxr1h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (mFxr1p).

S39A1_HUMAN
θ value	5.27518 (rank : 39)	NC score	0.062894 (rank : 12)
Query Neighborhood Hits	48	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NY26, Q8N2H7, Q9BTV0, Q9UBI7, Q9Y2Z7, Q9Y380	Gene names	SLC39A1, IRT1, ZIP1, ZIRTL
Domain Architecture
Description	Zinc transporter ZIP1 (Zinc-iron-regulated transporter-like) (hZIP1) (Solute carrier family 39 member 1).

FXR2_MOUSE
θ value	6.88961 (rank : 40)	NC score	0.024273 (rank : 31)
Query Neighborhood Hits	48	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

K1958_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.013891 (rank : 41)
Query Neighborhood Hits	48	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N8K9, Q5T252, Q8TF43, Q96N02	Gene names	KIAA1958
Domain Architecture	No domain graphic available
Description	Protein KIAA1958.

S39A1_MOUSE
θ value	6.88961 (rank : 42)	NC score	0.055822 (rank : 14)
Query Neighborhood Hits	48	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZ03, Q99K44	Gene names	Slc39a1, Zip1, Zirtl
Domain Architecture
Description	Zinc transporter ZIP1 (Zinc-iron-regulated transporter-like) (Solute carrier family 39 member 1).

FXR2_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.024200 (rank : 32)
Query Neighborhood Hits	48	Target Neighborhood Hits	77	Shared Neighborhood Hits	7
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

JERKL_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.028130 (rank : 27)
Query Neighborhood Hits	48	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4A0	Gene names	JRKL
Domain Architecture
Description	Jerky protein homolog-like (HHMJG).

MYST3_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.009829 (rank : 42)
Query Neighborhood Hits	48	Target Neighborhood Hits	688	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

POT15_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.003940 (rank : 47)
Query Neighborhood Hits	48	Target Neighborhood Hits	893	Shared Neighborhood Hits	12
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

STX18_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.021638 (rank : 34)
Query Neighborhood Hits	48	Target Neighborhood Hits	225	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2W9, Q596L3, Q5TZP5	Gene names	STX18, GIG9
Domain Architecture	No domain graphic available
Description	Syntaxin-18 (Growth-inhibiting gene 9 protein).

TITIN_HUMAN
θ value	8.99809 (rank : 48)	NC score	-0.001249 (rank : 48)
Query Neighborhood Hits	48	Target Neighborhood Hits	2923	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

Hits sorted by NC score

S39A6_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	48
SwissProt Accessions	Q8C145, Q7TPP9, Q7TQE0, Q8R518	Gene names	Slc39a6
Domain Architecture	No domain graphic available
Description	Zinc transporter SLC39A6 precursor (Solute carrier family 39 member 6) (Endoplasmic reticulum membrane-linked protein) (Ermelin).

S39A6_HUMAN
NC score	0.991425 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	48	Target Neighborhood Hits	31	Shared Neighborhood Hits	20
SwissProt Accessions	Q13433, Q8IXR3, Q96HP5	Gene names	SLC39A6, LIV1
Domain Architecture	No domain graphic available
Description	Zinc transporter SLC39A6 precursor (Solute carrier family 39 member 6) (Estrogen-regulated protein LIV-1).

S39A5_HUMAN
NC score	0.824270 (rank : 3)	θ value	3.61944e-33 (rank : 3)
Query Neighborhood Hits	48	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZMH5, Q8N6Y3	Gene names	SLC39A5, ZIP5
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP5 precursor (Solute carrier family 39 member 5).

S39A5_MOUSE
NC score	0.810863 (rank : 4)	θ value	2.34606e-32 (rank : 4)
Query Neighborhood Hits	48	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D856, Q9D909	Gene names	Slc39a5, Zip5
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP5 precursor (Solute carrier family 39 member 5).

S39A4_HUMAN
NC score	0.797511 (rank : 5)	θ value	5.22648e-32 (rank : 5)
Query Neighborhood Hits	48	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P5W5, Q7L5S5, Q9H6T8, Q9NXC4	Gene names	SLC39A4, ZIP4
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP4 precursor (Solute carrier family 39 member 4).

S39A4_MOUSE
NC score	0.789830 (rank : 6)	θ value	1.16434e-31 (rank : 6)
Query Neighborhood Hits	48	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q78IQ7, Q8CHL4	Gene names	Slc39a4, Zip4
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP4 precursor (Solute carrier family 39 member 4) (Activated in W/Wv mouse stomach 2) (mAWMS2).

KE4_HUMAN
NC score	0.739592 (rank : 7)	θ value	5.07402e-19 (rank : 7)
Query Neighborhood Hits	48	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q92504, Q5STP8, Q9UIQ0	Gene names	SLC39A7, HKE4, RING5
Domain Architecture
Description	Zinc transporter SLC39A7 (Solute carrier family 39 member 7) (Histidine-rich membrane protein Ke4).

KE4_MOUSE
NC score	0.733958 (rank : 8)	θ value	1.47631e-18 (rank : 8)
Query Neighborhood Hits	48	Target Neighborhood Hits	29	Shared Neighborhood Hits	16
SwissProt Accessions	Q31125, Q3TVU6, Q9Z1W1	Gene names	Slc39a7, H2-Ke4, Hke4
Domain Architecture
Description	Zinc transporter SLC39A7 (Solute carrier family 39 member 7) (Histidine-rich membrane protein Ke4).

S39A2_HUMAN
NC score	0.170671 (rank : 9)	θ value	0.0736092 (rank : 10)
Query Neighborhood Hits	48	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NP94, Q96JT6	Gene names	SLC39A2, ZIP2
Domain Architecture
Description	Zinc transporter ZIP2 (Eti-1) (6A1) (hZIP2) (Solute carrier family 39 member 2).

NELFA_HUMAN
NC score	0.074855 (rank : 10)	θ value	0.0736092 (rank : 9)
Query Neighborhood Hits	48	Target Neighborhood Hits	161	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

NELFA_MOUSE
NC score	0.064489 (rank : 11)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	48	Target Neighborhood Hits	195	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

S39A1_HUMAN
NC score	0.062894 (rank : 12)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	48	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NY26, Q8N2H7, Q9BTV0, Q9UBI7, Q9Y2Z7, Q9Y380	Gene names	SLC39A1, IRT1, ZIP1, ZIRTL
Domain Architecture
Description	Zinc transporter ZIP1 (Zinc-iron-regulated transporter-like) (hZIP1) (Solute carrier family 39 member 1).

SRCH_HUMAN
NC score	0.057653 (rank : 13)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	48	Target Neighborhood Hits	225	Shared Neighborhood Hits	18
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

S39A1_MOUSE
NC score	0.055822 (rank : 14)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	48	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZ03, Q99K44	Gene names	Slc39a1, Zip1, Zirtl
Domain Architecture
Description	Zinc transporter ZIP1 (Zinc-iron-regulated transporter-like) (Solute carrier family 39 member 1).

LEO1_HUMAN
NC score	0.052544 (rank : 15)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	48	Target Neighborhood Hits	958	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

CCD55_MOUSE
NC score	0.051086 (rank : 16)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	48	Target Neighborhood Hits	519	Shared Neighborhood Hits	19
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

FILA_HUMAN
NC score	0.050868 (rank : 17)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	48	Target Neighborhood Hits	685	Shared Neighborhood Hits	19
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

LEO1_MOUSE
NC score	0.048419 (rank : 18)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	48	Target Neighborhood Hits	946	Shared Neighborhood Hits	17
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

ELOA1_HUMAN
NC score	0.040210 (rank : 19)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	48	Target Neighborhood Hits	388	Shared Neighborhood Hits	17
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

CDC5L_MOUSE
NC score	0.039660 (rank : 20)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	48	Target Neighborhood Hits	205	Shared Neighborhood Hits	4
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

RPTN_HUMAN
NC score	0.035794 (rank : 21)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	48	Target Neighborhood Hits	406	Shared Neighborhood Hits	16
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

CCD55_HUMAN
NC score	0.035249 (rank : 22)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	48	Target Neighborhood Hits	513	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CDC5L_HUMAN
NC score	0.032823 (rank : 23)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	48	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q99459, Q76N46, Q99974	Gene names	CDC5L, KIAA0432, PCDC5RP
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5- related protein).

STC2_MOUSE
NC score	0.032722 (rank : 24)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	48	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	O88452	Gene names	Stc2
Domain Architecture
Description	Stanniocalcin-2 precursor (STC-2).

STC2_HUMAN
NC score	0.030847 (rank : 25)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	48	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	O76061	Gene names	STC2
Domain Architecture
Description	Stanniocalcin-2 precursor (STC-2) (Stanniocalcin-related protein) (STCRP) (STC-related protein).

RPTN_MOUSE
NC score	0.030507 (rank : 26)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	48	Target Neighborhood Hits	650	Shared Neighborhood Hits	21
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

JERKL_HUMAN
NC score	0.028130 (rank : 27)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	48	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4A0	Gene names	JRKL
Domain Architecture
Description	Jerky protein homolog-like (HHMJG).

CHD1_HUMAN
NC score	0.027372 (rank : 28)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	48	Target Neighborhood Hits	337	Shared Neighborhood Hits	15
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

FXR1_HUMAN
NC score	0.024987 (rank : 29)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	48	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	P51114, Q7Z450, Q8N6R8	Gene names	FXR1
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (hFXR1P).

FXR1_MOUSE
NC score	0.024945 (rank : 30)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	48	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q61584, Q8VCU4, Q9R1E2, Q9R1E3, Q9R1E4, Q9R1E5, Q9WUA7, Q9WUA8, Q9WUA9	Gene names	Fxr1, Fxr1h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (mFxr1p).

FXR2_MOUSE
NC score	0.024273 (rank : 31)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	48	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVR4, Q9WVR5	Gene names	Fxr2, Fxr2h
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

FXR2_HUMAN
NC score	0.024200 (rank : 32)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	48	Target Neighborhood Hits	77	Shared Neighborhood Hits	7
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

PARP2_MOUSE
NC score	0.021797 (rank : 33)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	48	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

STX18_HUMAN
NC score	0.021638 (rank : 34)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	48	Target Neighborhood Hits	225	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2W9, Q596L3, Q5TZP5	Gene names	STX18, GIG9
Domain Architecture	No domain graphic available
Description	Syntaxin-18 (Growth-inhibiting gene 9 protein).

CHD1_MOUSE
NC score	0.020936 (rank : 35)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	48	Target Neighborhood Hits	266	Shared Neighborhood Hits	11
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

SH3K1_MOUSE
NC score	0.018543 (rank : 36)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	48	Target Neighborhood Hits	332	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SH3K1_HUMAN
NC score	0.017222 (rank : 37)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	48	Target Neighborhood Hits	341	Shared Neighborhood Hits	3
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

TUB_HUMAN
NC score	0.016757 (rank : 38)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	48	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P50607, O00293	Gene names	TUB
Domain Architecture
Description	Tubby protein homolog.

PPIG_HUMAN
NC score	0.016488 (rank : 39)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	48	Target Neighborhood Hits	670	Shared Neighborhood Hits	16
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

MDC1_HUMAN
NC score	0.014228 (rank : 40)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	48	Target Neighborhood Hits	1446	Shared Neighborhood Hits	11
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

K1958_HUMAN
NC score	0.013891 (rank : 41)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	48	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N8K9, Q5T252, Q8TF43, Q96N02	Gene names	KIAA1958
Domain Architecture	No domain graphic available
Description	Protein KIAA1958.

MYST3_MOUSE
NC score	0.009829 (rank : 42)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	48	Target Neighborhood Hits	688	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PEG3_MOUSE
NC score	0.007449 (rank : 43)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	48	Target Neighborhood Hits	1101	Shared Neighborhood Hits	18
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

RLF_HUMAN
NC score	0.005944 (rank : 44)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	48	Target Neighborhood Hits	775	Shared Neighborhood Hits	5
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

BICD1_HUMAN
NC score	0.005323 (rank : 45)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	48	Target Neighborhood Hits	844	Shared Neighborhood Hits	3
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

FATH_HUMAN
NC score	0.004635 (rank : 46)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	48	Target Neighborhood Hits	570	Shared Neighborhood Hits	2
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

POT15_HUMAN
NC score	0.003940 (rank : 47)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	48	Target Neighborhood Hits	893	Shared Neighborhood Hits	12
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

TITIN_HUMAN
NC score	-0.001249 (rank : 48)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	48	Target Neighborhood Hits	2923	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).