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Network neighborhood for query Sequence : KE4_HUMAN

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KE4_HUMAN
SwissProt Accessions	Q92504, Q5STP8, Q9UIQ0	Gene names	SLC39A7, HKE4, RING5
Domain Architecture
Description	Zinc transporter SLC39A7 (Solute carrier family 39 member 7) (Histidine-rich membrane protein Ke4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KE4_HUMAN
θ value	8.37844e-131 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q92504, Q5STP8, Q9UIQ0	Gene names	SLC39A7, HKE4, RING5
Domain Architecture
Description	Zinc transporter SLC39A7 (Solute carrier family 39 member 7) (Histidine-rich membrane protein Ke4).

KE4_MOUSE
θ value	8.69046e-120 (rank : 2)	NC score	0.991455 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	16
SwissProt Accessions	Q31125, Q3TVU6, Q9Z1W1	Gene names	Slc39a7, H2-Ke4, Hke4
Domain Architecture
Description	Zinc transporter SLC39A7 (Solute carrier family 39 member 7) (Histidine-rich membrane protein Ke4).

S39A4_MOUSE
θ value	1.5773e-20 (rank : 3)	NC score	0.767249 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q78IQ7, Q8CHL4	Gene names	Slc39a4, Zip4
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP4 precursor (Solute carrier family 39 member 4) (Activated in W/Wv mouse stomach 2) (mAWMS2).

S39A5_HUMAN
θ value	5.99374e-20 (rank : 4)	NC score	0.789481 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZMH5, Q8N6Y3	Gene names	SLC39A5, ZIP5
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP5 precursor (Solute carrier family 39 member 5).

S39A6_MOUSE
θ value	5.07402e-19 (rank : 5)	NC score	0.739592 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	48	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C145, Q7TPP9, Q7TQE0, Q8R518	Gene names	Slc39a6
Domain Architecture	No domain graphic available
Description	Zinc transporter SLC39A6 precursor (Solute carrier family 39 member 6) (Endoplasmic reticulum membrane-linked protein) (Ermelin).

S39A5_MOUSE
θ value	6.62687e-19 (rank : 6)	NC score	0.778863 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D856, Q9D909	Gene names	Slc39a5, Zip5
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP5 precursor (Solute carrier family 39 member 5).

S39A6_HUMAN
θ value	6.62687e-19 (rank : 7)	NC score	0.740567 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	Q13433, Q8IXR3, Q96HP5	Gene names	SLC39A6, LIV1
Domain Architecture	No domain graphic available
Description	Zinc transporter SLC39A6 precursor (Solute carrier family 39 member 6) (Estrogen-regulated protein LIV-1).

S39A4_HUMAN
θ value	1.47631e-18 (rank : 8)	NC score	0.767749 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P5W5, Q7L5S5, Q9H6T8, Q9NXC4	Gene names	SLC39A4, ZIP4
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP4 precursor (Solute carrier family 39 member 4).

FILA_HUMAN
θ value	0.00175202 (rank : 9)	NC score	0.114427 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	685	Shared Neighborhood Hits	12
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

RBY1A_HUMAN
θ value	0.0736092 (rank : 10)	NC score	0.052390 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	245	Shared Neighborhood Hits	9
SwissProt Accessions	Q15414, Q15377, Q8NHR0	Gene names	RBMY1A1, RBM1, YRRM1
Domain Architecture
Description	RNA-binding motif protein, Y chromosome, family 1 member A1 (RNA- binding motif protein 1).

S39A1_HUMAN
θ value	1.81305 (rank : 11)	NC score	0.069707 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NY26, Q8N2H7, Q9BTV0, Q9UBI7, Q9Y2Z7, Q9Y380	Gene names	SLC39A1, IRT1, ZIP1, ZIRTL
Domain Architecture
Description	Zinc transporter ZIP1 (Zinc-iron-regulated transporter-like) (hZIP1) (Solute carrier family 39 member 1).

CACB2_HUMAN
θ value	2.36792 (rank : 12)	NC score	0.020907 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

CCD55_HUMAN
θ value	2.36792 (rank : 13)	NC score	0.038515 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	513	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

PEG3_MOUSE
θ value	2.36792 (rank : 14)	NC score	0.012377 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	1101	Shared Neighborhood Hits	9
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

GBRT_HUMAN
θ value	3.0926 (rank : 15)	NC score	0.017593 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UN88, Q9NZK8	Gene names	GABRQ
Domain Architecture
Description	Gamma-aminobutyric-acid receptor subunit theta precursor (GABA(A) receptor subunit theta).

AP2A_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.024495 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	P05549, Q13777	Gene names	TFAP2A, AP2TF, TFAP2
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (AP-2 transcription factor) (Activator protein 2) (AP-2).

PO4F3_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.008670 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	307	Shared Neighborhood Hits	2
SwissProt Accessions	Q15319, O60557	Gene names	POU4F3, BRN3C
Domain Architecture
Description	POU domain, class 4, transcription factor 3 (Brain-specific homeobox/POU domain protein 3C) (Brn-3C).

RPTN_HUMAN
θ value	4.03905 (rank : 18)	NC score	0.043891 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

RPTN_MOUSE
θ value	4.03905 (rank : 19)	NC score	0.039659 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	650	Shared Neighborhood Hits	12
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

CCD55_MOUSE
θ value	5.27518 (rank : 20)	NC score	0.058726 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	519	Shared Neighborhood Hits	12
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

S39A1_MOUSE
θ value	5.27518 (rank : 21)	NC score	0.050756 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZ03, Q99K44	Gene names	Slc39a1, Zip1, Zirtl
Domain Architecture
Description	Zinc transporter ZIP1 (Zinc-iron-regulated transporter-like) (Solute carrier family 39 member 1).

AP2A_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.017499 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	P34056, Q60740, Q60741, Q60742, Q60743, Q62067, Q62068, Q62069, Q91VX0, Q9CRY4	Gene names	Tfap2a, Ap2tf, Tcfap2a
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (Activator protein 2) (AP-2).

S39A2_HUMAN
θ value	θ > 10 (rank : 23)	NC score	0.096259 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NP94, Q96JT6	Gene names	SLC39A2, ZIP2
Domain Architecture
Description	Zinc transporter ZIP2 (Eti-1) (6A1) (hZIP2) (Solute carrier family 39 member 2).

Hits sorted by NC score

KE4_HUMAN
NC score	0.999962 (rank : 1)	θ value	8.37844e-131 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q92504, Q5STP8, Q9UIQ0	Gene names	SLC39A7, HKE4, RING5
Domain Architecture
Description	Zinc transporter SLC39A7 (Solute carrier family 39 member 7) (Histidine-rich membrane protein Ke4).

KE4_MOUSE
NC score	0.991455 (rank : 2)	θ value	8.69046e-120 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	16
SwissProt Accessions	Q31125, Q3TVU6, Q9Z1W1	Gene names	Slc39a7, H2-Ke4, Hke4
Domain Architecture
Description	Zinc transporter SLC39A7 (Solute carrier family 39 member 7) (Histidine-rich membrane protein Ke4).

S39A5_HUMAN
NC score	0.789481 (rank : 3)	θ value	5.99374e-20 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZMH5, Q8N6Y3	Gene names	SLC39A5, ZIP5
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP5 precursor (Solute carrier family 39 member 5).

S39A5_MOUSE
NC score	0.778863 (rank : 4)	θ value	6.62687e-19 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D856, Q9D909	Gene names	Slc39a5, Zip5
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP5 precursor (Solute carrier family 39 member 5).

S39A4_HUMAN
NC score	0.767749 (rank : 5)	θ value	1.47631e-18 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P5W5, Q7L5S5, Q9H6T8, Q9NXC4	Gene names	SLC39A4, ZIP4
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP4 precursor (Solute carrier family 39 member 4).

S39A4_MOUSE
NC score	0.767249 (rank : 6)	θ value	1.5773e-20 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q78IQ7, Q8CHL4	Gene names	Slc39a4, Zip4
Domain Architecture	No domain graphic available
Description	Zinc transporter ZIP4 precursor (Solute carrier family 39 member 4) (Activated in W/Wv mouse stomach 2) (mAWMS2).

S39A6_HUMAN
NC score	0.740567 (rank : 7)	θ value	6.62687e-19 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	Q13433, Q8IXR3, Q96HP5	Gene names	SLC39A6, LIV1
Domain Architecture	No domain graphic available
Description	Zinc transporter SLC39A6 precursor (Solute carrier family 39 member 6) (Estrogen-regulated protein LIV-1).

S39A6_MOUSE
NC score	0.739592 (rank : 8)	θ value	5.07402e-19 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	48	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C145, Q7TPP9, Q7TQE0, Q8R518	Gene names	Slc39a6
Domain Architecture	No domain graphic available
Description	Zinc transporter SLC39A6 precursor (Solute carrier family 39 member 6) (Endoplasmic reticulum membrane-linked protein) (Ermelin).

FILA_HUMAN
NC score	0.114427 (rank : 9)	θ value	0.00175202 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	685	Shared Neighborhood Hits	12
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

S39A2_HUMAN
NC score	0.096259 (rank : 10)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NP94, Q96JT6	Gene names	SLC39A2, ZIP2
Domain Architecture
Description	Zinc transporter ZIP2 (Eti-1) (6A1) (hZIP2) (Solute carrier family 39 member 2).

S39A1_HUMAN
NC score	0.069707 (rank : 11)	θ value	1.81305 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NY26, Q8N2H7, Q9BTV0, Q9UBI7, Q9Y2Z7, Q9Y380	Gene names	SLC39A1, IRT1, ZIP1, ZIRTL
Domain Architecture
Description	Zinc transporter ZIP1 (Zinc-iron-regulated transporter-like) (hZIP1) (Solute carrier family 39 member 1).

CCD55_MOUSE
NC score	0.058726 (rank : 12)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	519	Shared Neighborhood Hits	12
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

RBY1A_HUMAN
NC score	0.052390 (rank : 13)	θ value	0.0736092 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	245	Shared Neighborhood Hits	9
SwissProt Accessions	Q15414, Q15377, Q8NHR0	Gene names	RBMY1A1, RBM1, YRRM1
Domain Architecture
Description	RNA-binding motif protein, Y chromosome, family 1 member A1 (RNA- binding motif protein 1).

S39A1_MOUSE
NC score	0.050756 (rank : 14)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZ03, Q99K44	Gene names	Slc39a1, Zip1, Zirtl
Domain Architecture
Description	Zinc transporter ZIP1 (Zinc-iron-regulated transporter-like) (Solute carrier family 39 member 1).

RPTN_HUMAN
NC score	0.043891 (rank : 15)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

RPTN_MOUSE
NC score	0.039659 (rank : 16)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	650	Shared Neighborhood Hits	12
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

CCD55_HUMAN
NC score	0.038515 (rank : 17)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	513	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

AP2A_HUMAN
NC score	0.024495 (rank : 18)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	P05549, Q13777	Gene names	TFAP2A, AP2TF, TFAP2
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (AP-2 transcription factor) (Activator protein 2) (AP-2).

CACB2_HUMAN
NC score	0.020907 (rank : 19)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

GBRT_HUMAN
NC score	0.017593 (rank : 20)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UN88, Q9NZK8	Gene names	GABRQ
Domain Architecture
Description	Gamma-aminobutyric-acid receptor subunit theta precursor (GABA(A) receptor subunit theta).

AP2A_MOUSE
NC score	0.017499 (rank : 21)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	P34056, Q60740, Q60741, Q60742, Q60743, Q62067, Q62068, Q62069, Q91VX0, Q9CRY4	Gene names	Tfap2a, Ap2tf, Tcfap2a
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (Activator protein 2) (AP-2).

PEG3_MOUSE
NC score	0.012377 (rank : 22)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	1101	Shared Neighborhood Hits	9
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

PO4F3_HUMAN
NC score	0.008670 (rank : 23)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	307	Shared Neighborhood Hits	2
SwissProt Accessions	Q15319, O60557	Gene names	POU4F3, BRN3C
Domain Architecture
Description	POU domain, class 4, transcription factor 3 (Brain-specific homeobox/POU domain protein 3C) (Brn-3C).