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Network neighborhood for query Sequence : CACB2_HUMAN

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CACB2_HUMAN
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CACB2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	99	Target Neighborhood Hits	99	Shared Neighborhood Hits	99
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

CACB2_MOUSE
θ value	0 (rank : 2)	NC score	0.992828 (rank : 2)
Query Neighborhood Hits	99	Target Neighborhood Hits	94	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

CACB1_MOUSE
θ value	7.23842e-175 (rank : 3)	NC score	0.980118 (rank : 5)
Query Neighborhood Hits	99	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R3Z5, O88517, Q7TPF2, Q8R3Z6, Q9EPT9	Gene names	Cacnb1, Cacnlb1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CACB1_HUMAN
θ value	3.5924e-174 (rank : 4)	NC score	0.980867 (rank : 3)
Query Neighborhood Hits	99	Target Neighborhood Hits	44	Shared Neighborhood Hits	28
SwissProt Accessions	Q02641, O15331, Q02639, Q02640, Q9C085	Gene names	CACNB1, CACNLB1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CACB4_HUMAN
θ value	3.25673e-167 (rank : 5)	NC score	0.980436 (rank : 4)
Query Neighborhood Hits	99	Target Neighborhood Hits	47	Shared Neighborhood Hits	28
SwissProt Accessions	O00305, O60515, Q96L40	Gene names	CACNB4, CACNLB4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

CACB4_MOUSE
θ value	6.82227e-149 (rank : 6)	NC score	0.979211 (rank : 6)
Query Neighborhood Hits	99	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R0S4, Q8BRN6, Q8CAJ9	Gene names	Cacnb4, Cacnlb4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

CACB3_HUMAN
θ value	1.7995e-141 (rank : 7)	NC score	0.977246 (rank : 7)
Query Neighborhood Hits	99	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	P54284, Q13913	Gene names	CACNB3, CACNLB3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3).

CACB3_MOUSE
θ value	3.06949e-141 (rank : 8)	NC score	0.977091 (rank : 8)
Query Neighborhood Hits	99	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	P54285	Gene names	Cacnb3, Cacnlb3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) (CCHB3).

DLG3_MOUSE
θ value	1.43324e-05 (rank : 9)	NC score	0.190173 (rank : 10)
Query Neighborhood Hits	99	Target Neighborhood Hits	274	Shared Neighborhood Hits	31
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG3_HUMAN
θ value	0.000270298 (rank : 10)	NC score	0.196271 (rank : 9)
Query Neighborhood Hits	99	Target Neighborhood Hits	269	Shared Neighborhood Hits	31
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG1_MOUSE
θ value	0.00035302 (rank : 11)	NC score	0.189618 (rank : 12)
Query Neighborhood Hits	99	Target Neighborhood Hits	285	Shared Neighborhood Hits	30
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

DLG1_HUMAN
θ value	0.000786445 (rank : 12)	NC score	0.190135 (rank : 11)
Query Neighborhood Hits	99	Target Neighborhood Hits	290	Shared Neighborhood Hits	33
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

CCD55_MOUSE
θ value	0.00298849 (rank : 13)	NC score	0.101496 (rank : 26)
Query Neighborhood Hits	99	Target Neighborhood Hits	519	Shared Neighborhood Hits	36
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CCD55_HUMAN
θ value	0.00390308 (rank : 14)	NC score	0.099020 (rank : 28)
Query Neighborhood Hits	99	Target Neighborhood Hits	513	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

GPTC8_HUMAN
θ value	0.00665767 (rank : 15)	NC score	0.092221 (rank : 32)
Query Neighborhood Hits	99	Target Neighborhood Hits	366	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

DLG2_HUMAN
θ value	0.00869519 (rank : 16)	NC score	0.152855 (rank : 20)
Query Neighborhood Hits	99	Target Neighborhood Hits	279	Shared Neighborhood Hits	31
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

CSKP_MOUSE
θ value	0.0193708 (rank : 17)	NC score	0.061491 (rank : 37)
Query Neighborhood Hits	99	Target Neighborhood Hits	1027	Shared Neighborhood Hits	37
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

CSKP_HUMAN
θ value	0.0252991 (rank : 18)	NC score	0.062113 (rank : 36)
Query Neighborhood Hits	99	Target Neighborhood Hits	1022	Shared Neighborhood Hits	36
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

DLG4_HUMAN
θ value	0.0330416 (rank : 19)	NC score	0.166025 (rank : 16)
Query Neighborhood Hits	99	Target Neighborhood Hits	286	Shared Neighborhood Hits	31
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_MOUSE
θ value	0.0330416 (rank : 20)	NC score	0.166377 (rank : 15)
Query Neighborhood Hits	99	Target Neighborhood Hits	282	Shared Neighborhood Hits	31
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

NIPBL_HUMAN
θ value	0.0563607 (rank : 21)	NC score	0.040009 (rank : 59)
Query Neighborhood Hits	99	Target Neighborhood Hits	1311	Shared Neighborhood Hits	45
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ARI5B_MOUSE
θ value	0.0736092 (rank : 22)	NC score	0.039678 (rank : 60)
Query Neighborhood Hits	99	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

DLG2_MOUSE
θ value	0.0736092 (rank : 23)	NC score	0.163347 (rank : 17)
Query Neighborhood Hits	99	Target Neighborhood Hits	271	Shared Neighborhood Hits	31
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

LEO1_HUMAN
θ value	0.125558 (rank : 24)	NC score	0.043170 (rank : 53)
Query Neighborhood Hits	99	Target Neighborhood Hits	958	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MPP6_MOUSE
θ value	0.163984 (rank : 25)	NC score	0.174820 (rank : 13)
Query Neighborhood Hits	99	Target Neighborhood Hits	187	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MPP6_HUMAN
θ value	0.21417 (rank : 26)	NC score	0.171760 (rank : 14)
Query Neighborhood Hits	99	Target Neighborhood Hits	180	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

MYT1_HUMAN
θ value	0.279714 (rank : 27)	NC score	0.030690 (rank : 70)
Query Neighborhood Hits	99	Target Neighborhood Hits	475	Shared Neighborhood Hits	13
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

MYT1_MOUSE
θ value	0.279714 (rank : 28)	NC score	0.031643 (rank : 67)
Query Neighborhood Hits	99	Target Neighborhood Hits	385	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

RB15B_HUMAN
θ value	0.279714 (rank : 29)	NC score	0.041715 (rank : 56)
Query Neighborhood Hits	99	Target Neighborhood Hits	251	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NDT2, Q6QE19, Q9BV96	Gene names	RBM15B
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

SRRM2_HUMAN
θ value	0.279714 (rank : 30)	NC score	0.042840 (rank : 54)
Query Neighborhood Hits	99	Target Neighborhood Hits	1296	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYTL5_MOUSE
θ value	0.279714 (rank : 31)	NC score	0.022334 (rank : 78)
Query Neighborhood Hits	99	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

EM55_HUMAN
θ value	0.47712 (rank : 32)	NC score	0.148173 (rank : 21)
Query Neighborhood Hits	99	Target Neighborhood Hits	228	Shared Neighborhood Hits	30
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

MPP5_HUMAN
θ value	0.47712 (rank : 33)	NC score	0.160766 (rank : 18)
Query Neighborhood Hits	99	Target Neighborhood Hits	231	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
θ value	0.47712 (rank : 34)	NC score	0.158860 (rank : 19)
Query Neighborhood Hits	99	Target Neighborhood Hits	226	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

TS101_HUMAN
θ value	0.47712 (rank : 35)	NC score	0.075666 (rank : 35)
Query Neighborhood Hits	99	Target Neighborhood Hits	359	Shared Neighborhood Hits	10
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

EM55_MOUSE
θ value	0.62314 (rank : 36)	NC score	0.146360 (rank : 22)
Query Neighborhood Hits	99	Target Neighborhood Hits	221	Shared Neighborhood Hits	29
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

FILA_HUMAN
θ value	0.62314 (rank : 37)	NC score	0.051154 (rank : 46)
Query Neighborhood Hits	99	Target Neighborhood Hits	685	Shared Neighborhood Hits	38
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

RPTN_HUMAN
θ value	0.62314 (rank : 38)	NC score	0.042025 (rank : 55)
Query Neighborhood Hits	99	Target Neighborhood Hits	406	Shared Neighborhood Hits	31
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

KCNA4_HUMAN
θ value	0.813845 (rank : 39)	NC score	0.008200 (rank : 98)
Query Neighborhood Hits	99	Target Neighborhood Hits	108	Shared Neighborhood Hits	6
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

PRPF3_HUMAN
θ value	0.813845 (rank : 40)	NC score	0.036765 (rank : 64)
Query Neighborhood Hits	99	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).

SNIP1_MOUSE
θ value	0.813845 (rank : 41)	NC score	0.052572 (rank : 42)
Query Neighborhood Hits	99	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BIZ6, Q3V106, Q8BIZ4	Gene names	Snip1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

SRCH_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.052036 (rank : 43)
Query Neighborhood Hits	99	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

SRRM2_MOUSE
θ value	0.813845 (rank : 43)	NC score	0.039089 (rank : 61)
Query Neighborhood Hits	99	Target Neighborhood Hits	1470	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

AFF4_HUMAN
θ value	1.06291 (rank : 44)	NC score	0.045164 (rank : 51)
Query Neighborhood Hits	99	Target Neighborhood Hits	611	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AFF4_MOUSE
θ value	1.06291 (rank : 45)	NC score	0.045093 (rank : 52)
Query Neighborhood Hits	99	Target Neighborhood Hits	581	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

ELOA1_HUMAN
θ value	1.06291 (rank : 46)	NC score	0.030760 (rank : 69)
Query Neighborhood Hits	99	Target Neighborhood Hits	388	Shared Neighborhood Hits	29
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

MARK3_HUMAN
θ value	1.06291 (rank : 47)	NC score	0.004673 (rank : 108)
Query Neighborhood Hits	99	Target Neighborhood Hits	893	Shared Neighborhood Hits	14
SwissProt Accessions	P27448, O60219, Q8TB41, Q8WX83, Q96RG1, Q9UMY9, Q9UN34	Gene names	MARK3, CTAK1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (Cdc25C- associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10).

LEO1_MOUSE
θ value	1.38821 (rank : 48)	NC score	0.037223 (rank : 62)
Query Neighborhood Hits	99	Target Neighborhood Hits	946	Shared Neighborhood Hits	35
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

RB15B_MOUSE
θ value	1.38821 (rank : 49)	NC score	0.031177 (rank : 68)
Query Neighborhood Hits	99	Target Neighborhood Hits	284	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PHZ5, Q8C6G2	Gene names	Rbm15b
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

RPTN_MOUSE
θ value	1.38821 (rank : 50)	NC score	0.040440 (rank : 58)
Query Neighborhood Hits	99	Target Neighborhood Hits	650	Shared Neighborhood Hits	40
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

BAZ2B_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.012537 (rank : 93)
Query Neighborhood Hits	99	Target Neighborhood Hits	803	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

ENL_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.030363 (rank : 71)
Query Neighborhood Hits	99	Target Neighborhood Hits	305	Shared Neighborhood Hits	16
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

KE4_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.020907 (rank : 80)
Query Neighborhood Hits	99	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q92504, Q5STP8, Q9UIQ0	Gene names	SLC39A7, HKE4, RING5
Domain Architecture
Description	Zinc transporter SLC39A7 (Solute carrier family 39 member 7) (Histidine-rich membrane protein Ke4).

MASTL_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.005753 (rank : 105)
Query Neighborhood Hits	99	Target Neighborhood Hits	894	Shared Neighborhood Hits	11
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

TCOF_MOUSE
θ value	2.36792 (rank : 55)	NC score	0.024904 (rank : 77)
Query Neighborhood Hits	99	Target Neighborhood Hits	471	Shared Neighborhood Hits	15
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

ANK2_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.008091 (rank : 99)
Query Neighborhood Hits	99	Target Neighborhood Hits	1615	Shared Neighborhood Hits	38
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CCNL1_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.027451 (rank : 72)
Query Neighborhood Hits	99	Target Neighborhood Hits	71	Shared Neighborhood Hits	20
SwissProt Accessions	Q52KE7, Q8BQ75, Q8R5H9, Q922K0, Q9CSZ3, Q9WV44	Gene names	Ccnl1, Ania6a, Ccn1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a).

CDKL5_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.005365 (rank : 106)
Query Neighborhood Hits	99	Target Neighborhood Hits	967	Shared Neighborhood Hits	22
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

DMP1_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.036997 (rank : 63)
Query Neighborhood Hits	99	Target Neighborhood Hits	491	Shared Neighborhood Hits	26
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

RAD50_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.003710 (rank : 110)
Query Neighborhood Hits	99	Target Neighborhood Hits	1366	Shared Neighborhood Hits	18
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

TITIN_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.004926 (rank : 107)
Query Neighborhood Hits	99	Target Neighborhood Hits	2923	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TS101_MOUSE
θ value	3.0926 (rank : 62)	NC score	0.049981 (rank : 50)
Query Neighborhood Hits	99	Target Neighborhood Hits	312	Shared Neighborhood Hits	8
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

AUTS2_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.017710 (rank : 84)
Query Neighborhood Hits	99	Target Neighborhood Hits	342	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

CD2L5_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.006407 (rank : 103)
Query Neighborhood Hits	99	Target Neighborhood Hits	987	Shared Neighborhood Hits	20
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

RBM34_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.014822 (rank : 87)
Query Neighborhood Hits	99	Target Neighborhood Hits	208	Shared Neighborhood Hits	10
SwissProt Accessions	P42696, Q8N2Z8, Q9H5A1	Gene names	RBM34, KIAA0117
Domain Architecture
Description	RNA-binding protein 34 (RNA-binding motif protein 34).

SCG1_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.026503 (rank : 75)
Query Neighborhood Hits	99	Target Neighborhood Hits	163	Shared Neighborhood Hits	15
SwissProt Accessions	P16014	Gene names	Chgb, Scg-1, Scg1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB).

ZC3H6_MOUSE
θ value	4.03905 (rank : 67)	NC score	0.017496 (rank : 85)
Query Neighborhood Hits	99	Target Neighborhood Hits	239	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ARHG4_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.020070 (rank : 82)
Query Neighborhood Hits	99	Target Neighborhood Hits	242	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

DDHD1_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.012053 (rank : 94)
Query Neighborhood Hits	99	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NEL9, Q8WVH3, Q96LL2, Q9C0F8	Gene names	DDHD1, KIAA1705
Domain Architecture
Description	Probable phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1).

KCNH7_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.004540 (rank : 109)
Query Neighborhood Hits	99	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

MPP4_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.098696 (rank : 29)
Query Neighborhood Hits	99	Target Neighborhood Hits	205	Shared Neighborhood Hits	25
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

PLK4_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.003190 (rank : 111)
Query Neighborhood Hits	99	Target Neighborhood Hits	884	Shared Neighborhood Hits	12
SwissProt Accessions	O00444, Q8IYF0, Q96Q95	Gene names	PLK4, SAK, STK18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

PQBP1_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.033577 (rank : 66)
Query Neighborhood Hits	99	Target Neighborhood Hits	85	Shared Neighborhood Hits	18
SwissProt Accessions	O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4	Gene names	PQBP1, NPW38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

PTK6_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.006303 (rank : 104)
Query Neighborhood Hits	99	Target Neighborhood Hits	1026	Shared Neighborhood Hits	30
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

SFR12_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.050678 (rank : 49)
Query Neighborhood Hits	99	Target Neighborhood Hits	486	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

XRCC1_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.020502 (rank : 81)
Query Neighborhood Hits	99	Target Neighborhood Hits	242	Shared Neighborhood Hits	13
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ARHG9_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.014646 (rank : 89)
Query Neighborhood Hits	99	Target Neighborhood Hits	235	Shared Neighborhood Hits	19
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

ARHG9_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.014706 (rank : 88)
Query Neighborhood Hits	99	Target Neighborhood Hits	234	Shared Neighborhood Hits	19
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

CCNL1_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.025770 (rank : 76)
Query Neighborhood Hits	99	Target Neighborhood Hits	79	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

DP13A_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.014057 (rank : 91)
Query Neighborhood Hits	99	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DP13A_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.014093 (rank : 90)
Query Neighborhood Hits	99	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

GRIN1_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.014042 (rank : 92)
Query Neighborhood Hits	99	Target Neighborhood Hits	681	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

NKTR_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.017735 (rank : 83)
Query Neighborhood Hits	99	Target Neighborhood Hits	417	Shared Neighborhood Hits	30
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NPHP1_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.026928 (rank : 74)
Query Neighborhood Hits	99	Target Neighborhood Hits	288	Shared Neighborhood Hits	18
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

NPHP1_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.087326 (rank : 33)
Query Neighborhood Hits	99	Target Neighborhood Hits	267	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

PQBP1_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.033797 (rank : 65)
Query Neighborhood Hits	99	Target Neighborhood Hits	111	Shared Neighborhood Hits	16
SwissProt Accessions	Q91VJ5, Q80WW2, Q9ER43, Q9QYY2	Gene names	Pqbp1, Npw38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

ARI5B_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.027074 (rank : 73)
Query Neighborhood Hits	99	Target Neighborhood Hits	328	Shared Neighborhood Hits	15
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

BRDT_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.010973 (rank : 95)
Query Neighborhood Hits	99	Target Neighborhood Hits	280	Shared Neighborhood Hits	9
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

CEP35_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.010327 (rank : 96)
Query Neighborhood Hits	99	Target Neighborhood Hits	811	Shared Neighborhood Hits	20
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

EDD1_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.006805 (rank : 102)
Query Neighborhood Hits	99	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EHMT1_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.003150 (rank : 112)
Query Neighborhood Hits	99	Target Neighborhood Hits	417	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

HXD3_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.002858 (rank : 114)
Query Neighborhood Hits	99	Target Neighborhood Hits	433	Shared Neighborhood Hits	5
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

HXD3_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.002903 (rank : 113)
Query Neighborhood Hits	99	Target Neighborhood Hits	435	Shared Neighborhood Hits	6
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

JHD2B_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.007785 (rank : 100)
Query Neighborhood Hits	99	Target Neighborhood Hits	171	Shared Neighborhood Hits	10
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

RBY1A_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.015319 (rank : 86)
Query Neighborhood Hits	99	Target Neighborhood Hits	245	Shared Neighborhood Hits	18
SwissProt Accessions	Q15414, Q15377, Q8NHR0	Gene names	RBMY1A1, RBM1, YRRM1
Domain Architecture
Description	RNA-binding motif protein, Y chromosome, family 1 member A1 (RNA- binding motif protein 1).

RIMS1_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.021568 (rank : 79)
Query Neighborhood Hits	99	Target Neighborhood Hits	437	Shared Neighborhood Hits	25
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SFR12_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.041296 (rank : 57)
Query Neighborhood Hits	99	Target Neighborhood Hits	553	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SIN3A_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.008227 (rank : 97)
Query Neighborhood Hits	99	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

TMOD3_MOUSE
θ value	8.99809 (rank : 99)	NC score	0.007281 (rank : 101)
Query Neighborhood Hits	99	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JHJ0, Q3TIT1	Gene names	Tmod3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

DLG5_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.051060 (rank : 47)
Query Neighborhood Hits	99	Target Neighborhood Hits	1088	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

KGUA_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.097999 (rank : 30)
Query Neighborhood Hits	99	Target Neighborhood Hits	41	Shared Neighborhood Hits	17
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

KGUA_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.120309 (rank : 23)
Query Neighborhood Hits	99	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

MPP2_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.117537 (rank : 24)
Query Neighborhood Hits	99	Target Neighborhood Hits	173	Shared Neighborhood Hits	23
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.109674 (rank : 25)
Query Neighborhood Hits	99	Target Neighborhood Hits	189	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

MPP3_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.100742 (rank : 27)
Query Neighborhood Hits	99	Target Neighborhood Hits	171	Shared Neighborhood Hits	20
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

MPP3_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.092924 (rank : 31)
Query Neighborhood Hits	99	Target Neighborhood Hits	165	Shared Neighborhood Hits	18
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

MPP4_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.085575 (rank : 34)
Query Neighborhood Hits	99	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

SYJ2B_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.050882 (rank : 48)
Query Neighborhood Hits	99	Target Neighborhood Hits	162	Shared Neighborhood Hits	12
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

ZO1_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.051992 (rank : 44)
Query Neighborhood Hits	99	Target Neighborhood Hits	474	Shared Neighborhood Hits	24
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.051558 (rank : 45)
Query Neighborhood Hits	99	Target Neighborhood Hits	453	Shared Neighborhood Hits	22
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO2_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.057142 (rank : 40)
Query Neighborhood Hits	99	Target Neighborhood Hits	289	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.057673 (rank : 39)
Query Neighborhood Hits	99	Target Neighborhood Hits	296	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO3_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.056966 (rank : 41)
Query Neighborhood Hits	99	Target Neighborhood Hits	219	Shared Neighborhood Hits	19
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ZO3_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.059395 (rank : 38)
Query Neighborhood Hits	99	Target Neighborhood Hits	224	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

Hits sorted by NC score

CACB2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	99	Target Neighborhood Hits	99	Shared Neighborhood Hits	99
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

CACB2_MOUSE
NC score	0.992828 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	99	Target Neighborhood Hits	94	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

CACB1_HUMAN
NC score	0.980867 (rank : 3)	θ value	3.5924e-174 (rank : 4)
Query Neighborhood Hits	99	Target Neighborhood Hits	44	Shared Neighborhood Hits	28
SwissProt Accessions	Q02641, O15331, Q02639, Q02640, Q9C085	Gene names	CACNB1, CACNLB1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CACB4_HUMAN
NC score	0.980436 (rank : 4)	θ value	3.25673e-167 (rank : 5)
Query Neighborhood Hits	99	Target Neighborhood Hits	47	Shared Neighborhood Hits	28
SwissProt Accessions	O00305, O60515, Q96L40	Gene names	CACNB4, CACNLB4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

CACB1_MOUSE
NC score	0.980118 (rank : 5)	θ value	7.23842e-175 (rank : 3)
Query Neighborhood Hits	99	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R3Z5, O88517, Q7TPF2, Q8R3Z6, Q9EPT9	Gene names	Cacnb1, Cacnlb1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1).

CACB4_MOUSE
NC score	0.979211 (rank : 6)	θ value	6.82227e-149 (rank : 6)
Query Neighborhood Hits	99	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R0S4, Q8BRN6, Q8CAJ9	Gene names	Cacnb4, Cacnlb4
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4).

CACB3_HUMAN
NC score	0.977246 (rank : 7)	θ value	1.7995e-141 (rank : 7)
Query Neighborhood Hits	99	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	P54284, Q13913	Gene names	CACNB3, CACNLB3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3).

CACB3_MOUSE
NC score	0.977091 (rank : 8)	θ value	3.06949e-141 (rank : 8)
Query Neighborhood Hits	99	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	P54285	Gene names	Cacnb3, Cacnlb3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) (CCHB3).

DLG3_HUMAN
NC score	0.196271 (rank : 9)	θ value	0.000270298 (rank : 10)
Query Neighborhood Hits	99	Target Neighborhood Hits	269	Shared Neighborhood Hits	31
SwissProt Accessions	Q92796, Q9ULI8	Gene names	DLG3, KIAA1232
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102) (Neuroendocrine-DLG) (XLMR).

DLG3_MOUSE
NC score	0.190173 (rank : 10)	θ value	1.43324e-05 (rank : 9)
Query Neighborhood Hits	99	Target Neighborhood Hits	274	Shared Neighborhood Hits	31
SwissProt Accessions	P70175	Gene names	Dlg3, Dlgh3
Domain Architecture
Description	Discs large homolog 3 (Synapse-associated protein 102) (SAP102).

DLG1_HUMAN
NC score	0.190135 (rank : 11)	θ value	0.000786445 (rank : 12)
Query Neighborhood Hits	99	Target Neighborhood Hits	290	Shared Neighborhood Hits	33
SwissProt Accessions	Q12959, Q12958	Gene names	DLG1
Domain Architecture
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (hDlg).

DLG1_MOUSE
NC score	0.189618 (rank : 12)	θ value	0.00035302 (rank : 11)
Query Neighborhood Hits	99	Target Neighborhood Hits	285	Shared Neighborhood Hits	30
SwissProt Accessions	Q811D0, Q62402, Q6PGB5, Q8CGN7	Gene names	Dlg1, Dlgh1
Domain Architecture	No domain graphic available
Description	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (Embryo-dlg/synapse-associated protein 97) (E-dlg/SAP97).

MPP6_MOUSE
NC score	0.174820 (rank : 13)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	99	Target Neighborhood Hits	187	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JLB0, Q9JLB1, Q9WV37	Gene names	Mpp6, Dlgh4, Pals2
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Protein associated with Lin-7 2) (Dlgh4 protein) (P55T protein).

MPP6_HUMAN
NC score	0.171760 (rank : 14)	θ value	0.21417 (rank : 26)
Query Neighborhood Hits	99	Target Neighborhood Hits	180	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZW5, Q9H0E1	Gene names	MPP6, VAM1
Domain Architecture
Description	MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1).

DLG4_MOUSE
NC score	0.166377 (rank : 15)	θ value	0.0330416 (rank : 20)
Query Neighborhood Hits	99	Target Neighborhood Hits	282	Shared Neighborhood Hits	31
SwissProt Accessions	Q62108, Q5NCV5, Q5NCV6, Q5NCV7, Q91WJ1	Gene names	Dlg4, Dlgh4, Psd95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG4_HUMAN
NC score	0.166025 (rank : 16)	θ value	0.0330416 (rank : 19)
Query Neighborhood Hits	99	Target Neighborhood Hits	286	Shared Neighborhood Hits	31
SwissProt Accessions	P78352, Q92941, Q9UKK8	Gene names	DLG4, PSD95
Domain Architecture
Description	Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90).

DLG2_MOUSE
NC score	0.163347 (rank : 17)	θ value	0.0736092 (rank : 23)
Query Neighborhood Hits	99	Target Neighborhood Hits	271	Shared Neighborhood Hits	31
SwissProt Accessions	Q91XM9, Q8BXK7, Q8BYG5	Gene names	Dlg2, Dlgh2
Domain Architecture	No domain graphic available
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

MPP5_HUMAN
NC score	0.160766 (rank : 18)	θ value	0.47712 (rank : 33)
Query Neighborhood Hits	99	Target Neighborhood Hits	231	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N3R9, Q7Z631, Q86T98, Q8N7I5, Q9H9Q0	Gene names	MPP5
Domain Architecture
Description	MAGUK p55 subfamily member 5.

MPP5_MOUSE
NC score	0.158860 (rank : 19)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	99	Target Neighborhood Hits	226	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JLB2	Gene names	Mpp5, Pals1
Domain Architecture
Description	MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1).

DLG2_HUMAN
NC score	0.152855 (rank : 20)	θ value	0.00869519 (rank : 16)
Query Neighborhood Hits	99	Target Neighborhood Hits	279	Shared Neighborhood Hits	31
SwissProt Accessions	Q15700, Q59G57, Q68CQ8, Q6ZTA8	Gene names	DLG2
Domain Architecture
Description	Discs large homolog 2 (Postsynaptic density protein PSD-93) (Channel- associated protein of synapse-110) (Chapsyn-110).

EM55_HUMAN
NC score	0.148173 (rank : 21)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	99	Target Neighborhood Hits	228	Shared Neighborhood Hits	30
SwissProt Accessions	Q00013	Gene names	MPP1, DXS552E, EMP55
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1).

EM55_MOUSE
NC score	0.146360 (rank : 22)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	99	Target Neighborhood Hits	221	Shared Neighborhood Hits	29
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

KGUA_MOUSE
NC score	0.120309 (rank : 23)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	99	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

MPP2_HUMAN
NC score	0.117537 (rank : 24)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	99	Target Neighborhood Hits	173	Shared Neighborhood Hits	23
SwissProt Accessions	Q14168, Q9BQJ2	Gene names	MPP2, DLG2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Discs large homolog 2).

MPP2_MOUSE
NC score	0.109674 (rank : 25)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	99	Target Neighborhood Hits	189	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WV34	Gene names	Mpp2, Dlgh2
Domain Architecture
Description	MAGUK p55 subfamily member 2 (Protein MPP2) (Dlgh2 protein).

CCD55_MOUSE
NC score	0.101496 (rank : 26)	θ value	0.00298849 (rank : 13)
Query Neighborhood Hits	99	Target Neighborhood Hits	519	Shared Neighborhood Hits	36
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

MPP3_HUMAN
NC score	0.100742 (rank : 27)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	99	Target Neighborhood Hits	171	Shared Neighborhood Hits	20
SwissProt Accessions	Q13368	Gene names	MPP3, DLG3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Discs large homolog 3).

CCD55_HUMAN
NC score	0.099020 (rank : 28)	θ value	0.00390308 (rank : 14)
Query Neighborhood Hits	99	Target Neighborhood Hits	513	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

MPP4_HUMAN
NC score	0.098696 (rank : 29)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	99	Target Neighborhood Hits	205	Shared Neighborhood Hits	25
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

KGUA_HUMAN
NC score	0.097999 (rank : 30)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	99	Target Neighborhood Hits	41	Shared Neighborhood Hits	17
SwissProt Accessions	Q16774	Gene names	GUK1, GMK
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

MPP3_MOUSE
NC score	0.092924 (rank : 31)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	99	Target Neighborhood Hits	165	Shared Neighborhood Hits	18
SwissProt Accessions	O88910	Gene names	Mpp3, Dlgh3
Domain Architecture
Description	MAGUK p55 subfamily member 3 (Protein MPP3) (Dlgh3 protein).

GPTC8_HUMAN
NC score	0.092221 (rank : 32)	θ value	0.00665767 (rank : 15)
Query Neighborhood Hits	99	Target Neighborhood Hits	366	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

NPHP1_MOUSE
NC score	0.087326 (rank : 33)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	99	Target Neighborhood Hits	267	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QY53, Q9D7G8, Q9QZP0, Q9WUZ2	Gene names	Nphp1, Nph1
Domain Architecture
Description	Nephrocystin-1.

MPP4_MOUSE
NC score	0.085575 (rank : 34)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	99	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

TS101_HUMAN
NC score	0.075666 (rank : 35)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	99	Target Neighborhood Hits	359	Shared Neighborhood Hits	10
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

CSKP_HUMAN
NC score	0.062113 (rank : 36)	θ value	0.0252991 (rank : 18)
Query Neighborhood Hits	99	Target Neighborhood Hits	1022	Shared Neighborhood Hits	36
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CSKP_MOUSE
NC score	0.061491 (rank : 37)	θ value	0.0193708 (rank : 17)
Query Neighborhood Hits	99	Target Neighborhood Hits	1027	Shared Neighborhood Hits	37
SwissProt Accessions	O70589, O70588	Gene names	Cask
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase).

ZO3_MOUSE
NC score	0.059395 (rank : 38)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	99	Target Neighborhood Hits	224	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXY1	Gene names	Tjp3, Zo3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

ZO2_MOUSE
NC score	0.057673 (rank : 39)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	99	Target Neighborhood Hits	296	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0U1, Q8K210	Gene names	Tjp2, Zo2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO2_HUMAN
NC score	0.057142 (rank : 40)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	99	Target Neighborhood Hits	289	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UDY2, Q15883, Q8N756, Q8NI14, Q99839, Q9UDY0, Q9UDY1	Gene names	TJP2, X104, ZO2
Domain Architecture
Description	Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2).

ZO3_HUMAN
NC score	0.056966 (rank : 41)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	99	Target Neighborhood Hits	219	Shared Neighborhood Hits	19
SwissProt Accessions	O95049	Gene names	TJP3, ZO3
Domain Architecture
Description	Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3).

SNIP1_MOUSE
NC score	0.052572 (rank : 42)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	99	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BIZ6, Q3V106, Q8BIZ4	Gene names	Snip1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

SRCH_HUMAN
NC score	0.052036 (rank : 43)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	99	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

ZO1_HUMAN
NC score	0.051992 (rank : 44)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	99	Target Neighborhood Hits	474	Shared Neighborhood Hits	24
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ZO1_MOUSE
NC score	0.051558 (rank : 45)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	99	Target Neighborhood Hits	453	Shared Neighborhood Hits	22
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

FILA_HUMAN
NC score	0.051154 (rank : 46)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	99	Target Neighborhood Hits	685	Shared Neighborhood Hits	38
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

DLG5_HUMAN
NC score	0.051060 (rank : 47)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	99	Target Neighborhood Hits	1088	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

SYJ2B_HUMAN
NC score	0.050882 (rank : 48)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	99	Target Neighborhood Hits	162	Shared Neighborhood Hits	12
SwissProt Accessions	P57105, Q96IA4	Gene names	SYNJ2BP, OMP25
Domain Architecture
Description	Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25).

SFR12_MOUSE
NC score	0.050678 (rank : 49)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	99	Target Neighborhood Hits	486	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

TS101_MOUSE
NC score	0.049981 (rank : 50)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	99	Target Neighborhood Hits	312	Shared Neighborhood Hits	8
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

AFF4_HUMAN
NC score	0.045164 (rank : 51)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	99	Target Neighborhood Hits	611	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AFF4_MOUSE
NC score	0.045093 (rank : 52)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	99	Target Neighborhood Hits	581	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

LEO1_HUMAN
NC score	0.043170 (rank : 53)	θ value	0.125558 (rank : 24)
Query Neighborhood Hits	99	Target Neighborhood Hits	958	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

SRRM2_HUMAN
NC score	0.042840 (rank : 54)	θ value	0.279714 (rank : 30)
Query Neighborhood Hits	99	Target Neighborhood Hits	1296	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

RPTN_HUMAN
NC score	0.042025 (rank : 55)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	99	Target Neighborhood Hits	406	Shared Neighborhood Hits	31
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

RB15B_HUMAN
NC score	0.041715 (rank : 56)	θ value	0.279714 (rank : 29)
Query Neighborhood Hits	99	Target Neighborhood Hits	251	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NDT2, Q6QE19, Q9BV96	Gene names	RBM15B
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

SFR12_HUMAN
NC score	0.041296 (rank : 57)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	99	Target Neighborhood Hits	553	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

RPTN_MOUSE
NC score	0.040440 (rank : 58)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	99	Target Neighborhood Hits	650	Shared Neighborhood Hits	40
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

NIPBL_HUMAN
NC score	0.040009 (rank : 59)	θ value	0.0563607 (rank : 21)
Query Neighborhood Hits	99	Target Neighborhood Hits	1311	Shared Neighborhood Hits	45
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ARI5B_MOUSE
NC score	0.039678 (rank : 60)	θ value	0.0736092 (rank : 22)
Query Neighborhood Hits	99	Target Neighborhood Hits	158	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

SRRM2_MOUSE
NC score	0.039089 (rank : 61)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	99	Target Neighborhood Hits	1470	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

LEO1_MOUSE
NC score	0.037223 (rank : 62)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	99	Target Neighborhood Hits	946	Shared Neighborhood Hits	35
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

DMP1_HUMAN
NC score	0.036997 (rank : 63)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	99	Target Neighborhood Hits	491	Shared Neighborhood Hits	26
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

PRPF3_HUMAN
NC score	0.036765 (rank : 64)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	99	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).

PQBP1_MOUSE
NC score	0.033797 (rank : 65)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	99	Target Neighborhood Hits	111	Shared Neighborhood Hits	16
SwissProt Accessions	Q91VJ5, Q80WW2, Q9ER43, Q9QYY2	Gene names	Pqbp1, Npw38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

PQBP1_HUMAN
NC score	0.033577 (rank : 66)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	99	Target Neighborhood Hits	85	Shared Neighborhood Hits	18
SwissProt Accessions	O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4	Gene names	PQBP1, NPW38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

MYT1_MOUSE
NC score	0.031643 (rank : 67)	θ value	0.279714 (rank : 28)
Query Neighborhood Hits	99	Target Neighborhood Hits	385	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

RB15B_MOUSE
NC score	0.031177 (rank : 68)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	99	Target Neighborhood Hits	284	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PHZ5, Q8C6G2	Gene names	Rbm15b
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

ELOA1_HUMAN
NC score	0.030760 (rank : 69)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	99	Target Neighborhood Hits	388	Shared Neighborhood Hits	29
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

MYT1_HUMAN
NC score	0.030690 (rank : 70)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	99	Target Neighborhood Hits	475	Shared Neighborhood Hits	13
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

ENL_HUMAN
NC score	0.030363 (rank : 71)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	99	Target Neighborhood Hits	305	Shared Neighborhood Hits	16
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

CCNL1_MOUSE
NC score	0.027451 (rank : 72)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	99	Target Neighborhood Hits	71	Shared Neighborhood Hits	20
SwissProt Accessions	Q52KE7, Q8BQ75, Q8R5H9, Q922K0, Q9CSZ3, Q9WV44	Gene names	Ccnl1, Ania6a, Ccn1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a).

ARI5B_HUMAN
NC score	0.027074 (rank : 73)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	99	Target Neighborhood Hits	328	Shared Neighborhood Hits	15
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

NPHP1_HUMAN
NC score	0.026928 (rank : 74)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	99	Target Neighborhood Hits	288	Shared Neighborhood Hits	18
SwissProt Accessions	O15259, O14837	Gene names	NPHP1, NPH1
Domain Architecture
Description	Nephrocystin-1 (Juvenile nephronophthisis 1 protein).

SCG1_MOUSE
NC score	0.026503 (rank : 75)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	99	Target Neighborhood Hits	163	Shared Neighborhood Hits	15
SwissProt Accessions	P16014	Gene names	Chgb, Scg-1, Scg1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB).

CCNL1_HUMAN
NC score	0.025770 (rank : 76)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	99	Target Neighborhood Hits	79	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

TCOF_MOUSE
NC score	0.024904 (rank : 77)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	99	Target Neighborhood Hits	471	Shared Neighborhood Hits	15
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

SYTL5_MOUSE
NC score	0.022334 (rank : 78)	θ value	0.279714 (rank : 31)
Query Neighborhood Hits	99	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

RIMS1_HUMAN
NC score	0.021568 (rank : 79)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	99	Target Neighborhood Hits	437	Shared Neighborhood Hits	25
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

KE4_HUMAN
NC score	0.020907 (rank : 80)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	99	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q92504, Q5STP8, Q9UIQ0	Gene names	SLC39A7, HKE4, RING5
Domain Architecture
Description	Zinc transporter SLC39A7 (Solute carrier family 39 member 7) (Histidine-rich membrane protein Ke4).

XRCC1_MOUSE
NC score	0.020502 (rank : 81)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	99	Target Neighborhood Hits	242	Shared Neighborhood Hits	13
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ARHG4_HUMAN
NC score	0.020070 (rank : 82)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	99	Target Neighborhood Hits	242	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NR80, Q9HDC6, Q9UPP0	Gene names	ARHGEF4, KIAA1112
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 4 (APC-stimulated guanine nucleotide exchange factor) (Asef).

NKTR_MOUSE
NC score	0.017735 (rank : 83)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	99	Target Neighborhood Hits	417	Shared Neighborhood Hits	30
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

AUTS2_HUMAN
NC score	0.017710 (rank : 84)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	99	Target Neighborhood Hits	342	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

ZC3H6_MOUSE
NC score	0.017496 (rank : 85)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	99	Target Neighborhood Hits	239	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

RBY1A_HUMAN
NC score	0.015319 (rank : 86)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	99	Target Neighborhood Hits	245	Shared Neighborhood Hits	18
SwissProt Accessions	Q15414, Q15377, Q8NHR0	Gene names	RBMY1A1, RBM1, YRRM1
Domain Architecture
Description	RNA-binding motif protein, Y chromosome, family 1 member A1 (RNA- binding motif protein 1).

RBM34_HUMAN
NC score	0.014822 (rank : 87)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	99	Target Neighborhood Hits	208	Shared Neighborhood Hits	10
SwissProt Accessions	P42696, Q8N2Z8, Q9H5A1	Gene names	RBM34, KIAA0117
Domain Architecture
Description	RNA-binding protein 34 (RNA-binding motif protein 34).

ARHG9_MOUSE
NC score	0.014706 (rank : 88)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	99	Target Neighborhood Hits	234	Shared Neighborhood Hits	19
SwissProt Accessions	Q3UTH8, Q3TQ60, Q80U06, Q8CAF9	Gene names	Arhgef9, Kiaa0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin).

ARHG9_HUMAN
NC score	0.014646 (rank : 89)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	99	Target Neighborhood Hits	235	Shared Neighborhood Hits	19
SwissProt Accessions	O43307, Q5JSL6	Gene names	ARHGEF9, KIAA0424
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 9 (Rac/Cdc42 guanine nucleotide exchange factor 9) (Collybistin) (PEM-2 homolog).

DP13A_MOUSE
NC score	0.014093 (rank : 90)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	99	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DP13A_HUMAN
NC score	0.014057 (rank : 91)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	99	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

GRIN1_HUMAN
NC score	0.014042 (rank : 92)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	99	Target Neighborhood Hits	681	Shared Neighborhood Hits	14
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

BAZ2B_HUMAN
NC score	0.012537 (rank : 93)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	99	Target Neighborhood Hits	803	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

DDHD1_HUMAN
NC score	0.012053 (rank : 94)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	99	Target Neighborhood Hits	40	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NEL9, Q8WVH3, Q96LL2, Q9C0F8	Gene names	DDHD1, KIAA1705
Domain Architecture
Description	Probable phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1).

BRDT_HUMAN
NC score	0.010973 (rank : 95)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	99	Target Neighborhood Hits	280	Shared Neighborhood Hits	9
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

CEP35_HUMAN
NC score	0.010327 (rank : 96)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	99	Target Neighborhood Hits	811	Shared Neighborhood Hits	20
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

SIN3A_MOUSE
NC score	0.008227 (rank : 97)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	99	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

KCNA4_HUMAN
NC score	0.008200 (rank : 98)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	99	Target Neighborhood Hits	108	Shared Neighborhood Hits	6
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

ANK2_HUMAN
NC score	0.008091 (rank : 99)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	99	Target Neighborhood Hits	1615	Shared Neighborhood Hits	38
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

JHD2B_HUMAN
NC score	0.007785 (rank : 100)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	99	Target Neighborhood Hits	171	Shared Neighborhood Hits	10
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

TMOD3_MOUSE
NC score	0.007281 (rank : 101)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	99	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JHJ0, Q3TIT1	Gene names	Tmod3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

EDD1_HUMAN
NC score	0.006805 (rank : 102)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	99	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

CD2L5_HUMAN
NC score	0.006407 (rank : 103)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	99	Target Neighborhood Hits	987	Shared Neighborhood Hits	20
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

PTK6_MOUSE
NC score	0.006303 (rank : 104)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	99	Target Neighborhood Hits	1026	Shared Neighborhood Hits	30
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

MASTL_HUMAN
NC score	0.005753 (rank : 105)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	99	Target Neighborhood Hits	894	Shared Neighborhood Hits	11
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

CDKL5_HUMAN
NC score	0.005365 (rank : 106)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	99	Target Neighborhood Hits	967	Shared Neighborhood Hits	22
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

TITIN_HUMAN
NC score	0.004926 (rank : 107)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	99	Target Neighborhood Hits	2923	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

MARK3_HUMAN
NC score	0.004673 (rank : 108)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	99	Target Neighborhood Hits	893	Shared Neighborhood Hits	14
SwissProt Accessions	P27448, O60219, Q8TB41, Q8WX83, Q96RG1, Q9UMY9, Q9UN34	Gene names	MARK3, CTAK1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (Cdc25C- associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10).

KCNH7_MOUSE
NC score	0.004540 (rank : 109)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	99	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

RAD50_MOUSE
NC score	0.003710 (rank : 110)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	99	Target Neighborhood Hits	1366	Shared Neighborhood Hits	18
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

PLK4_HUMAN
NC score	0.003190 (rank : 111)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	99	Target Neighborhood Hits	884	Shared Neighborhood Hits	12
SwissProt Accessions	O00444, Q8IYF0, Q96Q95	Gene names	PLK4, SAK, STK18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

EHMT1_HUMAN
NC score	0.003150 (rank : 112)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	99	Target Neighborhood Hits	417	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

HXD3_MOUSE
NC score	0.002903 (rank : 113)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	99	Target Neighborhood Hits	435	Shared Neighborhood Hits	6
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

HXD3_HUMAN
NC score	0.002858 (rank : 114)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	99	Target Neighborhood Hits	433	Shared Neighborhood Hits	5
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).