Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : PQBP1_HUMAN

For an explanation of this page, click here

PQBP1_HUMAN
SwissProt Accessions	O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4	Gene names	PQBP1, NPW38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PQBP1_HUMAN
θ value	7.59556e-124 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	85	Target Neighborhood Hits	85	Shared Neighborhood Hits	85
SwissProt Accessions	O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4	Gene names	PQBP1, NPW38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

PQBP1_MOUSE
θ value	2.29227e-112 (rank : 2)	NC score	0.944943 (rank : 2)
Query Neighborhood Hits	85	Target Neighborhood Hits	111	Shared Neighborhood Hits	56
SwissProt Accessions	Q91VJ5, Q80WW2, Q9ER43, Q9QYY2	Gene names	Pqbp1, Npw38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

CCD55_HUMAN
θ value	0.000270298 (rank : 3)	NC score	0.218584 (rank : 3)
Query Neighborhood Hits	85	Target Neighborhood Hits	513	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

LEO1_MOUSE
θ value	0.00298849 (rank : 4)	NC score	0.166944 (rank : 4)
Query Neighborhood Hits	85	Target Neighborhood Hits	946	Shared Neighborhood Hits	59
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
θ value	0.00509761 (rank : 5)	NC score	0.166403 (rank : 5)
Query Neighborhood Hits	85	Target Neighborhood Hits	958	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NIPBL_HUMAN
θ value	0.0252991 (rank : 6)	NC score	0.128261 (rank : 15)
Query Neighborhood Hits	85	Target Neighborhood Hits	1311	Shared Neighborhood Hits	56
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

DIDO1_HUMAN
θ value	0.0431538 (rank : 7)	NC score	0.099285 (rank : 24)
Query Neighborhood Hits	85	Target Neighborhood Hits	960	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

AHTF1_HUMAN
θ value	0.0736092 (rank : 8)	NC score	0.071558 (rank : 54)
Query Neighborhood Hits	85	Target Neighborhood Hits	286	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

NELFE_MOUSE
θ value	0.0736092 (rank : 9)	NC score	0.153094 (rank : 6)
Query Neighborhood Hits	85	Target Neighborhood Hits	118	Shared Neighborhood Hits	18
SwissProt Accessions	P19426, P97485, P97486, Q9CZN3	Gene names	Rdbp, D17h6s45, Nelfe, Rd
Domain Architecture
Description	Negative elongation factor E (NELF-E) (RD protein).

NPBL_MOUSE
θ value	0.125558 (rank : 10)	NC score	0.134614 (rank : 12)
Query Neighborhood Hits	85	Target Neighborhood Hits	1041	Shared Neighborhood Hits	55
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NELFE_HUMAN
θ value	0.21417 (rank : 11)	NC score	0.142591 (rank : 8)
Query Neighborhood Hits	85	Target Neighborhood Hits	107	Shared Neighborhood Hits	16
SwissProt Accessions	P18615, Q5JP74, Q5JP75, Q96F56, Q9NPK2	Gene names	RDBP, NELFE, RD
Domain Architecture
Description	Negative elongation factor E (NELF-E) (RD protein).

K1688_HUMAN
θ value	0.279714 (rank : 12)	NC score	0.082395 (rank : 36)
Query Neighborhood Hits	85	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

CNGB3_HUMAN
θ value	0.365318 (rank : 13)	NC score	0.035050 (rank : 110)
Query Neighborhood Hits	85	Target Neighborhood Hits	206	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

PRP40_HUMAN
θ value	0.365318 (rank : 14)	NC score	0.137082 (rank : 10)
Query Neighborhood Hits	85	Target Neighborhood Hits	442	Shared Neighborhood Hits	34
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	0.365318 (rank : 15)	NC score	0.127076 (rank : 16)
Query Neighborhood Hits	85	Target Neighborhood Hits	447	Shared Neighborhood Hits	34
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

YLPM1_HUMAN
θ value	0.365318 (rank : 16)	NC score	0.064047 (rank : 75)
Query Neighborhood Hits	85	Target Neighborhood Hits	670	Shared Neighborhood Hits	19
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

AKAP1_HUMAN
θ value	0.47712 (rank : 17)	NC score	0.090252 (rank : 30)
Query Neighborhood Hits	85	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

CROP_HUMAN
θ value	0.47712 (rank : 18)	NC score	0.123964 (rank : 17)
Query Neighborhood Hits	85	Target Neighborhood Hits	402	Shared Neighborhood Hits	31
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

RPTN_HUMAN
θ value	0.47712 (rank : 19)	NC score	0.109275 (rank : 20)
Query Neighborhood Hits	85	Target Neighborhood Hits	406	Shared Neighborhood Hits	49
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

RU17_HUMAN
θ value	0.62314 (rank : 20)	NC score	0.080394 (rank : 38)
Query Neighborhood Hits	85	Target Neighborhood Hits	280	Shared Neighborhood Hits	21
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

UBP8_HUMAN
θ value	0.62314 (rank : 21)	NC score	0.048391 (rank : 101)
Query Neighborhood Hits	85	Target Neighborhood Hits	751	Shared Neighborhood Hits	36
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

NKTR_MOUSE
θ value	0.813845 (rank : 22)	NC score	0.072903 (rank : 47)
Query Neighborhood Hits	85	Target Neighborhood Hits	417	Shared Neighborhood Hits	42
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NUCB1_HUMAN
θ value	0.813845 (rank : 23)	NC score	0.072213 (rank : 51)
Query Neighborhood Hits	85	Target Neighborhood Hits	359	Shared Neighborhood Hits	12
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

NUCB1_MOUSE
θ value	0.813845 (rank : 24)	NC score	0.068358 (rank : 62)
Query Neighborhood Hits	85	Target Neighborhood Hits	414	Shared Neighborhood Hits	15
SwissProt Accessions	Q02819, Q3TU42, Q9CWA1, Q9D8J4, Q9DBL3	Gene names	Nucb1, Nuc, Nucb
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

RU17_MOUSE
θ value	0.813845 (rank : 25)	NC score	0.072894 (rank : 48)
Query Neighborhood Hits	85	Target Neighborhood Hits	278	Shared Neighborhood Hits	18
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

APBB3_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.066740 (rank : 67)
Query Neighborhood Hits	85	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

ATRX_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.073161 (rank : 46)
Query Neighborhood Hits	85	Target Neighborhood Hits	682	Shared Neighborhood Hits	36
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

BAZ2B_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.040268 (rank : 104)
Query Neighborhood Hits	85	Target Neighborhood Hits	803	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

SFR15_HUMAN
θ value	1.06291 (rank : 29)	NC score	0.098770 (rank : 25)
Query Neighborhood Hits	85	Target Neighborhood Hits	368	Shared Neighborhood Hits	25
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

MAP1A_HUMAN
θ value	1.38821 (rank : 30)	NC score	0.066094 (rank : 68)
Query Neighborhood Hits	85	Target Neighborhood Hits	1626	Shared Neighborhood Hits	53
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

FIP1_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.085344 (rank : 34)
Query Neighborhood Hits	85	Target Neighborhood Hits	118	Shared Neighborhood Hits	21
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

MTR1L_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.004943 (rank : 124)
Query Neighborhood Hits	85	Target Neighborhood Hits	1180	Shared Neighborhood Hits	4
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

SRCH_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.104733 (rank : 21)
Query Neighborhood Hits	85	Target Neighborhood Hits	225	Shared Neighborhood Hits	22
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

ZC313_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.131190 (rank : 13)
Query Neighborhood Hits	85	Target Neighborhood Hits	772	Shared Neighborhood Hits	56
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

AP3B1_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.045062 (rank : 103)
Query Neighborhood Hits	85	Target Neighborhood Hits	302	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

ATRX_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.077483 (rank : 42)
Query Neighborhood Hits	85	Target Neighborhood Hits	842	Shared Neighborhood Hits	40
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

K1688_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.064420 (rank : 73)
Query Neighborhood Hits	85	Target Neighborhood Hits	188	Shared Neighborhood Hits	7
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

KI21A_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.020711 (rank : 121)
Query Neighborhood Hits	85	Target Neighborhood Hits	1543	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

PIN1_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.086971 (rank : 33)
Query Neighborhood Hits	85	Target Neighborhood Hits	60	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

TCRG1_HUMAN
θ value	2.36792 (rank : 40)	NC score	0.092392 (rank : 29)
Query Neighborhood Hits	85	Target Neighborhood Hits	929	Shared Neighborhood Hits	45
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	2.36792 (rank : 41)	NC score	0.093353 (rank : 28)
Query Neighborhood Hits	85	Target Neighborhood Hits	947	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

UBP8_MOUSE
θ value	2.36792 (rank : 42)	NC score	0.038850 (rank : 105)
Query Neighborhood Hits	85	Target Neighborhood Hits	362	Shared Neighborhood Hits	21
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

ANR12_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.047201 (rank : 102)
Query Neighborhood Hits	85	Target Neighborhood Hits	1081	Shared Neighborhood Hits	47
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

CROP_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.118608 (rank : 18)
Query Neighborhood Hits	85	Target Neighborhood Hits	403	Shared Neighborhood Hits	32
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

DYNA_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.026854 (rank : 117)
Query Neighborhood Hits	85	Target Neighborhood Hits	1194	Shared Neighborhood Hits	22
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

PIN1_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.072686 (rank : 50)
Query Neighborhood Hits	85	Target Neighborhood Hits	59	Shared Neighborhood Hits	11
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

SFR11_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.129949 (rank : 14)
Query Neighborhood Hits	85	Target Neighborhood Hits	246	Shared Neighborhood Hits	28
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SFR12_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.139018 (rank : 9)
Query Neighborhood Hits	85	Target Neighborhood Hits	553	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SFR12_MOUSE
θ value	3.0926 (rank : 49)	NC score	0.137023 (rank : 11)
Query Neighborhood Hits	85	Target Neighborhood Hits	486	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

APBB3_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.052381 (rank : 90)
Query Neighborhood Hits	85	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

CALR_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.031085 (rank : 115)
Query Neighborhood Hits	85	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	P14211	Gene names	Calr
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60).

DMXL2_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.036639 (rank : 108)
Query Neighborhood Hits	85	Target Neighborhood Hits	374	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

LC7L2_MOUSE
θ value	4.03905 (rank : 53)	NC score	0.077337 (rank : 43)
Query Neighborhood Hits	85	Target Neighborhood Hits	244	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

RBM25_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.083490 (rank : 35)
Query Neighborhood Hits	85	Target Neighborhood Hits	682	Shared Neighborhood Hits	34
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

SETD2_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.053357 (rank : 87)
Query Neighborhood Hits	85	Target Neighborhood Hits	412	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SFR17_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.116096 (rank : 19)
Query Neighborhood Hits	85	Target Neighborhood Hits	325	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

ZC3H6_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.034933 (rank : 111)
Query Neighborhood Hits	85	Target Neighborhood Hits	228	Shared Neighborhood Hits	13
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

BAG3_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.035792 (rank : 109)
Query Neighborhood Hits	85	Target Neighborhood Hits	314	Shared Neighborhood Hits	8
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

BAG3_MOUSE
θ value	5.27518 (rank : 59)	NC score	0.037237 (rank : 106)
Query Neighborhood Hits	85	Target Neighborhood Hits	513	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

C8AP2_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.075649 (rank : 44)
Query Neighborhood Hits	85	Target Neighborhood Hits	405	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CACB2_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.033577 (rank : 112)
Query Neighborhood Hits	85	Target Neighborhood Hits	99	Shared Neighborhood Hits	18
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

DHX15_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.019295 (rank : 123)
Query Neighborhood Hits	85	Target Neighborhood Hits	50	Shared Neighborhood Hits	8
SwissProt Accessions	O43143, Q9NQT7	Gene names	DHX15, DBP1, DDX15
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15) (ATP-dependent RNA helicase #46).

PHF3_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.097309 (rank : 27)
Query Neighborhood Hits	85	Target Neighborhood Hits	419	Shared Neighborhood Hits	34
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

RBBP6_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.100197 (rank : 23)
Query Neighborhood Hits	85	Target Neighborhood Hits	1135	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

YTDC1_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.088565 (rank : 32)
Query Neighborhood Hits	85	Target Neighborhood Hits	458	Shared Neighborhood Hits	39
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

CCD55_MOUSE
θ value	6.88961 (rank : 66)	NC score	0.150579 (rank : 7)
Query Neighborhood Hits	85	Target Neighborhood Hits	519	Shared Neighborhood Hits	54
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

DMP1_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.079178 (rank : 39)
Query Neighborhood Hits	85	Target Neighborhood Hits	491	Shared Neighborhood Hits	36
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DYNA_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.023925 (rank : 120)
Query Neighborhood Hits	85	Target Neighborhood Hits	1084	Shared Neighborhood Hits	21
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

NCBP1_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.019697 (rank : 122)
Query Neighborhood Hits	85	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UYV9, Q7TNE8	Gene names	Ncbp1
Domain Architecture	No domain graphic available
Description	Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (NCBP 80 kDa subunit) (CBP80).

SPT6H_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.048460 (rank : 99)
Query Neighborhood Hits	85	Target Neighborhood Hits	104	Shared Neighborhood Hits	10
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

SPT6H_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.048445 (rank : 100)
Query Neighborhood Hits	85	Target Neighborhood Hits	104	Shared Neighborhood Hits	12
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

WDR60_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.089755 (rank : 31)
Query Neighborhood Hits	85	Target Neighborhood Hits	286	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

WDR60_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.069065 (rank : 59)
Query Neighborhood Hits	85	Target Neighborhood Hits	344	Shared Neighborhood Hits	34
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

AFF4_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.056434 (rank : 86)
Query Neighborhood Hits	85	Target Neighborhood Hits	611	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

ARS2_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.069636 (rank : 56)
Query Neighborhood Hits	85	Target Neighborhood Hits	186	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

ARS2_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.068639 (rank : 60)
Query Neighborhood Hits	85	Target Neighborhood Hits	212	Shared Neighborhood Hits	24
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

CCAR1_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.066972 (rank : 66)
Query Neighborhood Hits	85	Target Neighborhood Hits	444	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

CPSF6_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.033236 (rank : 114)
Query Neighborhood Hits	85	Target Neighborhood Hits	359	Shared Neighborhood Hits	13
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	8.99809 (rank : 79)	NC score	0.033424 (rank : 113)
Query Neighborhood Hits	85	Target Neighborhood Hits	356	Shared Neighborhood Hits	13
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

ELOA1_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.061930 (rank : 80)
Query Neighborhood Hits	85	Target Neighborhood Hits	388	Shared Neighborhood Hits	42
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

IWS1_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.069149 (rank : 58)
Query Neighborhood Hits	85	Target Neighborhood Hits	1241	Shared Neighborhood Hits	52
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RBY1A_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.029366 (rank : 116)
Query Neighborhood Hits	85	Target Neighborhood Hits	245	Shared Neighborhood Hits	17
SwissProt Accessions	Q15414, Q15377, Q8NHR0	Gene names	RBMY1A1, RBM1, YRRM1
Domain Architecture
Description	RNA-binding motif protein, Y chromosome, family 1 member A1 (RNA- binding motif protein 1).

SMRC1_MOUSE
θ value	8.99809 (rank : 83)	NC score	0.025883 (rank : 118)
Query Neighborhood Hits	85	Target Neighborhood Hits	459	Shared Neighborhood Hits	19
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

SPBP_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.036733 (rank : 107)
Query Neighborhood Hits	85	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P15501	Gene names	Sbp
Domain Architecture
Description	Prostatic spermine-binding protein precursor (SBP) (Major prostatic secretory glycoprotein) (P25).

UBP33_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.023992 (rank : 119)
Query Neighborhood Hits	85	Target Neighborhood Hits	157	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

ACINU_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.065490 (rank : 69)
Query Neighborhood Hits	85	Target Neighborhood Hits	828	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACINU_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.053137 (rank : 89)
Query Neighborhood Hits	85	Target Neighborhood Hits	712	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

C8AP2_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.098037 (rank : 26)
Query Neighborhood Hits	85	Target Neighborhood Hits	548	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CCAR1_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.050376 (rank : 98)
Query Neighborhood Hits	85	Target Neighborhood Hits	414	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

CIR_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.060202 (rank : 82)
Query Neighborhood Hits	85	Target Neighborhood Hits	249	Shared Neighborhood Hits	25
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

CYLC1_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.070050 (rank : 55)
Query Neighborhood Hits	85	Target Neighborhood Hits	408	Shared Neighborhood Hits	28
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

CYLC2_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.078731 (rank : 40)
Query Neighborhood Hits	85	Target Neighborhood Hits	223	Shared Neighborhood Hits	26
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

DMP1_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.064775 (rank : 71)
Query Neighborhood Hits	85	Target Neighborhood Hits	498	Shared Neighborhood Hits	26
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DSPP_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.060972 (rank : 81)
Query Neighborhood Hits	85	Target Neighborhood Hits	645	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DSPP_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.062073 (rank : 79)
Query Neighborhood Hits	85	Target Neighborhood Hits	491	Shared Neighborhood Hits	24
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

FILA_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.064665 (rank : 72)
Query Neighborhood Hits	85	Target Neighborhood Hits	685	Shared Neighborhood Hits	49
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

FIP1_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.063158 (rank : 76)
Query Neighborhood Hits	85	Target Neighborhood Hits	120	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

GPTC8_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.059500 (rank : 84)
Query Neighborhood Hits	85	Target Neighborhood Hits	366	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

HIRP3_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.053275 (rank : 88)
Query Neighborhood Hits	85	Target Neighborhood Hits	323	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

IF38_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.069448 (rank : 57)
Query Neighborhood Hits	85	Target Neighborhood Hits	98	Shared Neighborhood Hits	11
SwissProt Accessions	Q99613, O00215	Gene names	EIF3S8
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110) (eIF3c).

IWS1_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.067236 (rank : 65)
Query Neighborhood Hits	85	Target Neighborhood Hits	1258	Shared Neighborhood Hits	54
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LC7L2_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.068302 (rank : 63)
Query Neighborhood Hits	85	Target Neighborhood Hits	235	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y383, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1	Gene names	LUC7L2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2.

MPP8_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.051931 (rank : 94)
Query Neighborhood Hits	85	Target Neighborhood Hits	948	Shared Neighborhood Hits	49
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NKTR_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.059826 (rank : 83)
Query Neighborhood Hits	85	Target Neighborhood Hits	658	Shared Neighborhood Hits	53
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NSBP1_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.077884 (rank : 41)
Query Neighborhood Hits	85	Target Neighborhood Hits	251	Shared Neighborhood Hits	25
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

NSBP1_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.064093 (rank : 74)
Query Neighborhood Hits	85	Target Neighborhood Hits	681	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

NUCKS_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.081512 (rank : 37)
Query Neighborhood Hits	85	Target Neighborhood Hits	143	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

NUCKS_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.101327 (rank : 22)
Query Neighborhood Hits	85	Target Neighborhood Hits	114	Shared Neighborhood Hits	16
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

PPIG_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.068417 (rank : 61)
Query Neighborhood Hits	85	Target Neighborhood Hits	670	Shared Neighborhood Hits	53
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

PTMA_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.062738 (rank : 77)
Query Neighborhood Hits	85	Target Neighborhood Hits	88	Shared Neighborhood Hits	9
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PTMA_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.064925 (rank : 70)
Query Neighborhood Hits	85	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

RBBP6_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.067582 (rank : 64)
Query Neighborhood Hits	85	Target Neighborhood Hits	1014	Shared Neighborhood Hits	49
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

REN3B_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.072752 (rank : 49)
Query Neighborhood Hits	85	Target Neighborhood Hits	412	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

RPTN_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.062157 (rank : 78)
Query Neighborhood Hits	85	Target Neighborhood Hits	650	Shared Neighborhood Hits	50
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SFRIP_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.073233 (rank : 45)
Query Neighborhood Hits	85	Target Neighborhood Hits	530	Shared Neighborhood Hits	40
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SFRS4_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.051368 (rank : 96)
Query Neighborhood Hits	85	Target Neighborhood Hits	384	Shared Neighborhood Hits	25
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

SFRS4_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.051595 (rank : 95)
Query Neighborhood Hits	85	Target Neighborhood Hits	406	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

SNIP1_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.050576 (rank : 97)
Query Neighborhood Hits	85	Target Neighborhood Hits	113	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BIZ6, Q3V106, Q8BIZ4	Gene names	Snip1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

T2FA_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.052105 (rank : 92)
Query Neighborhood Hits	85	Target Neighborhood Hits	228	Shared Neighborhood Hits	15
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

T2_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.072142 (rank : 52)
Query Neighborhood Hits	85	Target Neighborhood Hits	140	Shared Neighborhood Hits	18
SwissProt Accessions	Q06666	Gene names	Srst, T2
Domain Architecture	No domain graphic available
Description	Octapeptide-repeat protein T2.

TCAL5_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.052077 (rank : 93)
Query Neighborhood Hits	85	Target Neighborhood Hits	806	Shared Neighborhood Hits	44
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

THOC2_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.071802 (rank : 53)
Query Neighborhood Hits	85	Target Neighborhood Hits	337	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

TR150_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.052170 (rank : 91)
Query Neighborhood Hits	85	Target Neighborhood Hits	468	Shared Neighborhood Hits	41
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TXND2_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.057477 (rank : 85)
Query Neighborhood Hits	85	Target Neighborhood Hits	828	Shared Neighborhood Hits	45
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

Hits sorted by NC score

PQBP1_HUMAN
NC score	0.999962 (rank : 1)	θ value	7.59556e-124 (rank : 1)
Query Neighborhood Hits	85	Target Neighborhood Hits	85	Shared Neighborhood Hits	85
SwissProt Accessions	O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4	Gene names	PQBP1, NPW38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

PQBP1_MOUSE
NC score	0.944943 (rank : 2)	θ value	2.29227e-112 (rank : 2)
Query Neighborhood Hits	85	Target Neighborhood Hits	111	Shared Neighborhood Hits	56
SwissProt Accessions	Q91VJ5, Q80WW2, Q9ER43, Q9QYY2	Gene names	Pqbp1, Npw38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

CCD55_HUMAN
NC score	0.218584 (rank : 3)	θ value	0.000270298 (rank : 3)
Query Neighborhood Hits	85	Target Neighborhood Hits	513	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

LEO1_MOUSE
NC score	0.166944 (rank : 4)	θ value	0.00298849 (rank : 4)
Query Neighborhood Hits	85	Target Neighborhood Hits	946	Shared Neighborhood Hits	59
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
NC score	0.166403 (rank : 5)	θ value	0.00509761 (rank : 5)
Query Neighborhood Hits	85	Target Neighborhood Hits	958	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NELFE_MOUSE
NC score	0.153094 (rank : 6)	θ value	0.0736092 (rank : 9)
Query Neighborhood Hits	85	Target Neighborhood Hits	118	Shared Neighborhood Hits	18
SwissProt Accessions	P19426, P97485, P97486, Q9CZN3	Gene names	Rdbp, D17h6s45, Nelfe, Rd
Domain Architecture
Description	Negative elongation factor E (NELF-E) (RD protein).

CCD55_MOUSE
NC score	0.150579 (rank : 7)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	85	Target Neighborhood Hits	519	Shared Neighborhood Hits	54
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

NELFE_HUMAN
NC score	0.142591 (rank : 8)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	85	Target Neighborhood Hits	107	Shared Neighborhood Hits	16
SwissProt Accessions	P18615, Q5JP74, Q5JP75, Q96F56, Q9NPK2	Gene names	RDBP, NELFE, RD
Domain Architecture
Description	Negative elongation factor E (NELF-E) (RD protein).

SFR12_HUMAN
NC score	0.139018 (rank : 9)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	85	Target Neighborhood Hits	553	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

PRP40_HUMAN
NC score	0.137082 (rank : 10)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	85	Target Neighborhood Hits	442	Shared Neighborhood Hits	34
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

SFR12_MOUSE
NC score	0.137023 (rank : 11)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	85	Target Neighborhood Hits	486	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

NPBL_MOUSE
NC score	0.134614 (rank : 12)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	85	Target Neighborhood Hits	1041	Shared Neighborhood Hits	55
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

ZC313_HUMAN
NC score	0.131190 (rank : 13)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	85	Target Neighborhood Hits	772	Shared Neighborhood Hits	56
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

SFR11_HUMAN
NC score	0.129949 (rank : 14)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	85	Target Neighborhood Hits	246	Shared Neighborhood Hits	28
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

NIPBL_HUMAN
NC score	0.128261 (rank : 15)	θ value	0.0252991 (rank : 6)
Query Neighborhood Hits	85	Target Neighborhood Hits	1311	Shared Neighborhood Hits	56
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PRP40_MOUSE
NC score	0.127076 (rank : 16)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	85	Target Neighborhood Hits	447	Shared Neighborhood Hits	34
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

CROP_HUMAN
NC score	0.123964 (rank : 17)	θ value	0.47712 (rank : 18)
Query Neighborhood Hits	85	Target Neighborhood Hits	402	Shared Neighborhood Hits	31
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

CROP_MOUSE
NC score	0.118608 (rank : 18)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	85	Target Neighborhood Hits	403	Shared Neighborhood Hits	32
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

SFR17_HUMAN
NC score	0.116096 (rank : 19)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	85	Target Neighborhood Hits	325	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

RPTN_HUMAN
NC score	0.109275 (rank : 20)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	85	Target Neighborhood Hits	406	Shared Neighborhood Hits	49
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

SRCH_HUMAN
NC score	0.104733 (rank : 21)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	85	Target Neighborhood Hits	225	Shared Neighborhood Hits	22
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

NUCKS_MOUSE
NC score	0.101327 (rank : 22)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	85	Target Neighborhood Hits	114	Shared Neighborhood Hits	16
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

RBBP6_HUMAN
NC score	0.100197 (rank : 23)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	85	Target Neighborhood Hits	1135	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

DIDO1_HUMAN
NC score	0.099285 (rank : 24)	θ value	0.0431538 (rank : 7)
Query Neighborhood Hits	85	Target Neighborhood Hits	960	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

SFR15_HUMAN
NC score	0.098770 (rank : 25)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	85	Target Neighborhood Hits	368	Shared Neighborhood Hits	25
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

C8AP2_HUMAN
NC score	0.098037 (rank : 26)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	85	Target Neighborhood Hits	548	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

PHF3_HUMAN
NC score	0.097309 (rank : 27)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	85	Target Neighborhood Hits	419	Shared Neighborhood Hits	34
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

TCRG1_MOUSE
NC score	0.093353 (rank : 28)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	85	Target Neighborhood Hits	947	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TCRG1_HUMAN
NC score	0.092392 (rank : 29)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	85	Target Neighborhood Hits	929	Shared Neighborhood Hits	45
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

AKAP1_HUMAN
NC score	0.090252 (rank : 30)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	85	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

WDR60_HUMAN
NC score	0.089755 (rank : 31)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	85	Target Neighborhood Hits	286	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

YTDC1_HUMAN
NC score	0.088565 (rank : 32)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	85	Target Neighborhood Hits	458	Shared Neighborhood Hits	39
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

PIN1_MOUSE
NC score	0.086971 (rank : 33)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	85	Target Neighborhood Hits	60	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

FIP1_HUMAN
NC score	0.085344 (rank : 34)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	85	Target Neighborhood Hits	118	Shared Neighborhood Hits	21
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

RBM25_HUMAN
NC score	0.083490 (rank : 35)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	85	Target Neighborhood Hits	682	Shared Neighborhood Hits	34
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

K1688_HUMAN
NC score	0.082395 (rank : 36)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	85	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

NUCKS_HUMAN
NC score	0.081512 (rank : 37)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	85	Target Neighborhood Hits	143	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

RU17_HUMAN
NC score	0.080394 (rank : 38)	θ value	0.62314 (rank : 20)
Query Neighborhood Hits	85	Target Neighborhood Hits	280	Shared Neighborhood Hits	21
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

DMP1_HUMAN
NC score	0.079178 (rank : 39)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	85	Target Neighborhood Hits	491	Shared Neighborhood Hits	36
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

CYLC2_HUMAN
NC score	0.078731 (rank : 40)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	85	Target Neighborhood Hits	223	Shared Neighborhood Hits	26
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

NSBP1_HUMAN
NC score	0.077884 (rank : 41)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	85	Target Neighborhood Hits	251	Shared Neighborhood Hits	25
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

ATRX_HUMAN
NC score	0.077483 (rank : 42)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	85	Target Neighborhood Hits	842	Shared Neighborhood Hits	40
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

LC7L2_MOUSE
NC score	0.077337 (rank : 43)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	85	Target Neighborhood Hits	244	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

C8AP2_MOUSE
NC score	0.075649 (rank : 44)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	85	Target Neighborhood Hits	405	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

SFRIP_HUMAN
NC score	0.073233 (rank : 45)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	85	Target Neighborhood Hits	530	Shared Neighborhood Hits	40
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

ATRX_MOUSE
NC score	0.073161 (rank : 46)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	85	Target Neighborhood Hits	682	Shared Neighborhood Hits	36
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

NKTR_MOUSE
NC score	0.072903 (rank : 47)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	85	Target Neighborhood Hits	417	Shared Neighborhood Hits	42
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RU17_MOUSE
NC score	0.072894 (rank : 48)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	85	Target Neighborhood Hits	278	Shared Neighborhood Hits	18
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

REN3B_HUMAN
NC score	0.072752 (rank : 49)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	85	Target Neighborhood Hits	412	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

PIN1_HUMAN
NC score	0.072686 (rank : 50)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	85	Target Neighborhood Hits	59	Shared Neighborhood Hits	11
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

NUCB1_HUMAN
NC score	0.072213 (rank : 51)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	85	Target Neighborhood Hits	359	Shared Neighborhood Hits	12
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

T2_MOUSE
NC score	0.072142 (rank : 52)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	85	Target Neighborhood Hits	140	Shared Neighborhood Hits	18
SwissProt Accessions	Q06666	Gene names	Srst, T2
Domain Architecture	No domain graphic available
Description	Octapeptide-repeat protein T2.

THOC2_HUMAN
NC score	0.071802 (rank : 53)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	85	Target Neighborhood Hits	337	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

AHTF1_HUMAN
NC score	0.071558 (rank : 54)	θ value	0.0736092 (rank : 8)
Query Neighborhood Hits	85	Target Neighborhood Hits	286	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

CYLC1_HUMAN
NC score	0.070050 (rank : 55)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	85	Target Neighborhood Hits	408	Shared Neighborhood Hits	28
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

ARS2_HUMAN
NC score	0.069636 (rank : 56)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	85	Target Neighborhood Hits	186	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

IF38_HUMAN
NC score	0.069448 (rank : 57)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	85	Target Neighborhood Hits	98	Shared Neighborhood Hits	11
SwissProt Accessions	Q99613, O00215	Gene names	EIF3S8
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 8 (eIF3 p110) (eIF3c).

IWS1_HUMAN
NC score	0.069149 (rank : 58)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	85	Target Neighborhood Hits	1241	Shared Neighborhood Hits	52
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

WDR60_MOUSE
NC score	0.069065 (rank : 59)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	85	Target Neighborhood Hits	344	Shared Neighborhood Hits	34
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

ARS2_MOUSE
NC score	0.068639 (rank : 60)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	85	Target Neighborhood Hits	212	Shared Neighborhood Hits	24
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

PPIG_HUMAN
NC score	0.068417 (rank : 61)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	85	Target Neighborhood Hits	670	Shared Neighborhood Hits	53
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

NUCB1_MOUSE
NC score	0.068358 (rank : 62)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	85	Target Neighborhood Hits	414	Shared Neighborhood Hits	15
SwissProt Accessions	Q02819, Q3TU42, Q9CWA1, Q9D8J4, Q9DBL3	Gene names	Nucb1, Nuc, Nucb
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

LC7L2_HUMAN
NC score	0.068302 (rank : 63)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	85	Target Neighborhood Hits	235	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y383, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1	Gene names	LUC7L2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2.

RBBP6_MOUSE
NC score	0.067582 (rank : 64)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	85	Target Neighborhood Hits	1014	Shared Neighborhood Hits	49
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

IWS1_MOUSE
NC score	0.067236 (rank : 65)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	85	Target Neighborhood Hits	1258	Shared Neighborhood Hits	54
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CCAR1_HUMAN
NC score	0.066972 (rank : 66)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	85	Target Neighborhood Hits	444	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

APBB3_HUMAN
NC score	0.066740 (rank : 67)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	85	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	O95704, Q9NYX6, Q9NYX7, Q9NYX8	Gene names	APBB3, FE65L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2).

MAP1A_HUMAN
NC score	0.066094 (rank : 68)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	85	Target Neighborhood Hits	1626	Shared Neighborhood Hits	53
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

ACINU_HUMAN
NC score	0.065490 (rank : 69)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	85	Target Neighborhood Hits	828	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

PTMA_MOUSE
NC score	0.064925 (rank : 70)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	85	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

DMP1_MOUSE
NC score	0.064775 (rank : 71)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	85	Target Neighborhood Hits	498	Shared Neighborhood Hits	26
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

FILA_HUMAN
NC score	0.064665 (rank : 72)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	85	Target Neighborhood Hits	685	Shared Neighborhood Hits	49
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

K1688_MOUSE
NC score	0.064420 (rank : 73)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	85	Target Neighborhood Hits	188	Shared Neighborhood Hits	7
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

NSBP1_MOUSE
NC score	0.064093 (rank : 74)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	85	Target Neighborhood Hits	681	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

YLPM1_HUMAN
NC score	0.064047 (rank : 75)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	85	Target Neighborhood Hits	670	Shared Neighborhood Hits	19
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

FIP1_MOUSE
NC score	0.063158 (rank : 76)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	85	Target Neighborhood Hits	120	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

PTMA_HUMAN
NC score	0.062738 (rank : 77)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	85	Target Neighborhood Hits	88	Shared Neighborhood Hits	9
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

RPTN_MOUSE
NC score	0.062157 (rank : 78)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	85	Target Neighborhood Hits	650	Shared Neighborhood Hits	50
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

DSPP_MOUSE
NC score	0.062073 (rank : 79)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	85	Target Neighborhood Hits	491	Shared Neighborhood Hits	24
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ELOA1_HUMAN
NC score	0.061930 (rank : 80)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	85	Target Neighborhood Hits	388	Shared Neighborhood Hits	42
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

DSPP_HUMAN
NC score	0.060972 (rank : 81)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	85	Target Neighborhood Hits	645	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

CIR_HUMAN
NC score	0.060202 (rank : 82)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	85	Target Neighborhood Hits	249	Shared Neighborhood Hits	25
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

NKTR_HUMAN
NC score	0.059826 (rank : 83)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	85	Target Neighborhood Hits	658	Shared Neighborhood Hits	53
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

GPTC8_HUMAN
NC score	0.059500 (rank : 84)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	85	Target Neighborhood Hits	366	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

TXND2_MOUSE
NC score	0.057477 (rank : 85)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	85	Target Neighborhood Hits	828	Shared Neighborhood Hits	45
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

AFF4_HUMAN
NC score	0.056434 (rank : 86)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	85	Target Neighborhood Hits	611	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

SETD2_HUMAN
NC score	0.053357 (rank : 87)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	85	Target Neighborhood Hits	412	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

HIRP3_HUMAN
NC score	0.053275 (rank : 88)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	85	Target Neighborhood Hits	323	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

ACINU_MOUSE
NC score	0.053137 (rank : 89)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	85	Target Neighborhood Hits	712	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

APBB3_MOUSE
NC score	0.052381 (rank : 90)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	85	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R1C9	Gene names	Apbb3
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 3.

TR150_MOUSE
NC score	0.052170 (rank : 91)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	85	Target Neighborhood Hits	468	Shared Neighborhood Hits	41
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

T2FA_HUMAN
NC score	0.052105 (rank : 92)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	85	Target Neighborhood Hits	228	Shared Neighborhood Hits	15
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TCAL5_HUMAN
NC score	0.052077 (rank : 93)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	85	Target Neighborhood Hits	806	Shared Neighborhood Hits	44
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

MPP8_HUMAN
NC score	0.051931 (rank : 94)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	85	Target Neighborhood Hits	948	Shared Neighborhood Hits	49
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

SFRS4_MOUSE
NC score	0.051595 (rank : 95)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	85	Target Neighborhood Hits	406	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

SFRS4_HUMAN
NC score	0.051368 (rank : 96)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	85	Target Neighborhood Hits	384	Shared Neighborhood Hits	25
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

SNIP1_MOUSE
NC score	0.050576 (rank : 97)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	85	Target Neighborhood Hits	113	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BIZ6, Q3V106, Q8BIZ4	Gene names	Snip1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

CCAR1_MOUSE
NC score	0.050376 (rank : 98)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	85	Target Neighborhood Hits	414	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

SPT6H_HUMAN
NC score	0.048460 (rank : 99)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	85	Target Neighborhood Hits	104	Shared Neighborhood Hits	10
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

SPT6H_MOUSE
NC score	0.048445 (rank : 100)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	85	Target Neighborhood Hits	104	Shared Neighborhood Hits	12
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

UBP8_HUMAN
NC score	0.048391 (rank : 101)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	85	Target Neighborhood Hits	751	Shared Neighborhood Hits	36
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

ANR12_HUMAN
NC score	0.047201 (rank : 102)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	85	Target Neighborhood Hits	1081	Shared Neighborhood Hits	47
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

AP3B1_MOUSE
NC score	0.045062 (rank : 103)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	85	Target Neighborhood Hits	302	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

BAZ2B_HUMAN
NC score	0.040268 (rank : 104)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	85	Target Neighborhood Hits	803	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

UBP8_MOUSE
NC score	0.038850 (rank : 105)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	85	Target Neighborhood Hits	362	Shared Neighborhood Hits	21
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

BAG3_MOUSE
NC score	0.037237 (rank : 106)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	85	Target Neighborhood Hits	513	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

SPBP_MOUSE
NC score	0.036733 (rank : 107)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	85	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P15501	Gene names	Sbp
Domain Architecture
Description	Prostatic spermine-binding protein precursor (SBP) (Major prostatic secretory glycoprotein) (P25).

DMXL2_HUMAN
NC score	0.036639 (rank : 108)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	85	Target Neighborhood Hits	374	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

BAG3_HUMAN
NC score	0.035792 (rank : 109)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	85	Target Neighborhood Hits	314	Shared Neighborhood Hits	8
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

CNGB3_HUMAN
NC score	0.035050 (rank : 110)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	85	Target Neighborhood Hits	206	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

ZC3H6_HUMAN
NC score	0.034933 (rank : 111)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	85	Target Neighborhood Hits	228	Shared Neighborhood Hits	13
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

CACB2_HUMAN
NC score	0.033577 (rank : 112)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	85	Target Neighborhood Hits	99	Shared Neighborhood Hits	18
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

CPSF6_MOUSE
NC score	0.033424 (rank : 113)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	85	Target Neighborhood Hits	356	Shared Neighborhood Hits	13
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CPSF6_HUMAN
NC score	0.033236 (rank : 114)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	85	Target Neighborhood Hits	359	Shared Neighborhood Hits	13
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CALR_MOUSE
NC score	0.031085 (rank : 115)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	85	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	P14211	Gene names	Calr
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60).

RBY1A_HUMAN
NC score	0.029366 (rank : 116)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	85	Target Neighborhood Hits	245	Shared Neighborhood Hits	17
SwissProt Accessions	Q15414, Q15377, Q8NHR0	Gene names	RBMY1A1, RBM1, YRRM1
Domain Architecture
Description	RNA-binding motif protein, Y chromosome, family 1 member A1 (RNA- binding motif protein 1).

DYNA_HUMAN
NC score	0.026854 (rank : 117)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	85	Target Neighborhood Hits	1194	Shared Neighborhood Hits	22
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

SMRC1_MOUSE
NC score	0.025883 (rank : 118)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	85	Target Neighborhood Hits	459	Shared Neighborhood Hits	19
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

UBP33_HUMAN
NC score	0.023992 (rank : 119)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	85	Target Neighborhood Hits	157	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

DYNA_MOUSE
NC score	0.023925 (rank : 120)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	85	Target Neighborhood Hits	1084	Shared Neighborhood Hits	21
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

KI21A_HUMAN
NC score	0.020711 (rank : 121)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	85	Target Neighborhood Hits	1543	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

NCBP1_MOUSE
NC score	0.019697 (rank : 122)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	85	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UYV9, Q7TNE8	Gene names	Ncbp1
Domain Architecture	No domain graphic available
Description	Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (NCBP 80 kDa subunit) (CBP80).

DHX15_HUMAN
NC score	0.019295 (rank : 123)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	85	Target Neighborhood Hits	50	Shared Neighborhood Hits	8
SwissProt Accessions	O43143, Q9NQT7	Gene names	DHX15, DBP1, DDX15
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.1.-) (DEAH box protein 15) (ATP-dependent RNA helicase #46).

MTR1L_HUMAN
NC score	0.004943 (rank : 124)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	85	Target Neighborhood Hits	1180	Shared Neighborhood Hits	4
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).