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Network neighborhood for query Sequence : CALR_MOUSE

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CALR_MOUSE
SwissProt Accessions	P14211	Gene names	Calr
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CALR_HUMAN
θ value	0 (rank : 1)	NC score	0.993732 (rank : 2)
Query Neighborhood Hits	68	Target Neighborhood Hits	85	Shared Neighborhood Hits	52
SwissProt Accessions	P27797	Gene names	CALR, CRTC
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) (grp60).

CALR_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	68
SwissProt Accessions	P14211	Gene names	Calr
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60).

CALR3_HUMAN
θ value	7.14227e-106 (rank : 3)	NC score	0.962502 (rank : 3)
Query Neighborhood Hits	68	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q96L12, Q96LN3	Gene names	CALR3, CRT2
Domain Architecture
Description	Calreticulin-3 precursor (Calreticulin-2).

CALR3_MOUSE
θ value	8.73085e-104 (rank : 4)	NC score	0.959767 (rank : 4)
Query Neighborhood Hits	68	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D9Q6	Gene names	Calr3, Crt2
Domain Architecture
Description	Calreticulin-3 precursor (Calreticulin-2).

CLGN_MOUSE
θ value	1.6097e-65 (rank : 5)	NC score	0.879937 (rank : 8)
Query Neighborhood Hits	68	Target Neighborhood Hits	142	Shared Neighborhood Hits	15
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

CALX_MOUSE
θ value	2.56992e-63 (rank : 6)	NC score	0.896774 (rank : 5)
Query Neighborhood Hits	68	Target Neighborhood Hits	76	Shared Neighborhood Hits	23
SwissProt Accessions	P35564	Gene names	Canx
Domain Architecture
Description	Calnexin precursor.

CALX_HUMAN
θ value	2.17557e-62 (rank : 7)	NC score	0.892789 (rank : 6)
Query Neighborhood Hits	68	Target Neighborhood Hits	96	Shared Neighborhood Hits	26
SwissProt Accessions	P27824	Gene names	CANX
Domain Architecture
Description	Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90).

CLGN_HUMAN
θ value	3.47335e-60 (rank : 8)	NC score	0.887215 (rank : 7)
Query Neighborhood Hits	68	Target Neighborhood Hits	111	Shared Neighborhood Hits	22
SwissProt Accessions	O14967	Gene names	CLGN
Domain Architecture
Description	Calmegin precursor.

ERIC1_HUMAN
θ value	0.00020696 (rank : 9)	NC score	0.145073 (rank : 9)
Query Neighborhood Hits	68	Target Neighborhood Hits	364	Shared Neighborhood Hits	18
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

LEO1_MOUSE
θ value	0.00228821 (rank : 10)	NC score	0.099491 (rank : 10)
Query Neighborhood Hits	68	Target Neighborhood Hits	946	Shared Neighborhood Hits	36
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
θ value	0.0113563 (rank : 11)	NC score	0.085137 (rank : 14)
Query Neighborhood Hits	68	Target Neighborhood Hits	958	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

SEC63_MOUSE
θ value	0.0113563 (rank : 12)	NC score	0.093652 (rank : 12)
Query Neighborhood Hits	68	Target Neighborhood Hits	601	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_HUMAN
θ value	0.0431538 (rank : 13)	NC score	0.085223 (rank : 13)
Query Neighborhood Hits	68	Target Neighborhood Hits	586	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

NSBP1_MOUSE
θ value	0.0563607 (rank : 14)	NC score	0.098641 (rank : 11)
Query Neighborhood Hits	68	Target Neighborhood Hits	681	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

F10A1_HUMAN
θ value	0.279714 (rank : 15)	NC score	0.055230 (rank : 22)
Query Neighborhood Hits	68	Target Neighborhood Hits	312	Shared Neighborhood Hits	13
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

TCAL5_HUMAN
θ value	0.365318 (rank : 16)	NC score	0.061586 (rank : 19)
Query Neighborhood Hits	68	Target Neighborhood Hits	806	Shared Neighborhood Hits	31
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

F10A5_HUMAN
θ value	0.47712 (rank : 17)	NC score	0.054080 (rank : 23)
Query Neighborhood Hits	68	Target Neighborhood Hits	277	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

ITSN1_HUMAN
θ value	0.62314 (rank : 18)	NC score	0.019566 (rank : 49)
Query Neighborhood Hits	68	Target Neighborhood Hits	1757	Shared Neighborhood Hits	29
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

GP137_MOUSE
θ value	0.813845 (rank : 19)	NC score	0.052469 (rank : 24)
Query Neighborhood Hits	68	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q60865, Q60758, Q61620	Gene names	M11s1, Gpiap, Gpiap1, Gpip137
Domain Architecture	No domain graphic available
Description	GPI-anchored protein p137 (p137GPI).

ITSN1_MOUSE
θ value	0.813845 (rank : 20)	NC score	0.016655 (rank : 53)
Query Neighborhood Hits	68	Target Neighborhood Hits	1669	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

CC47_MOUSE
θ value	1.38821 (rank : 21)	NC score	0.056243 (rank : 21)
Query Neighborhood Hits	68	Target Neighborhood Hits	245	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

F10A4_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.045803 (rank : 28)
Query Neighborhood Hits	68	Target Neighborhood Hits	249	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZP2	Gene names	FAM10A4
Domain Architecture	No domain graphic available
Description	Protein FAM10A4.

LRRC6_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.034464 (rank : 35)
Query Neighborhood Hits	68	Target Neighborhood Hits	181	Shared Neighborhood Hits	11
SwissProt Accessions	Q86X45, Q13648, Q4G183	Gene names	LRRC6, LRTP, TSLRP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 6 (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein).

OSBL8_HUMAN
θ value	1.38821 (rank : 24)	NC score	0.026162 (rank : 45)
Query Neighborhood Hits	68	Target Neighborhood Hits	289	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

PPIG_HUMAN
θ value	1.38821 (rank : 25)	NC score	0.026883 (rank : 43)
Query Neighborhood Hits	68	Target Neighborhood Hits	670	Shared Neighborhood Hits	32
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

SCG2_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.043469 (rank : 30)
Query Neighborhood Hits	68	Target Neighborhood Hits	190	Shared Neighborhood Hits	7
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

NALP5_MOUSE
θ value	1.81305 (rank : 27)	NC score	0.029539 (rank : 41)
Query Neighborhood Hits	68	Target Neighborhood Hits	560	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

RPTN_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.032379 (rank : 37)
Query Neighborhood Hits	68	Target Neighborhood Hits	406	Shared Neighborhood Hits	17
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

TXND2_HUMAN
θ value	1.81305 (rank : 29)	NC score	0.035422 (rank : 33)
Query Neighborhood Hits	68	Target Neighborhood Hits	793	Shared Neighborhood Hits	23
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

DMN_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.021100 (rank : 48)
Query Neighborhood Hits	68	Target Neighborhood Hits	690	Shared Neighborhood Hits	22
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

PHF20_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.027490 (rank : 42)
Query Neighborhood Hits	68	Target Neighborhood Hits	394	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

CCD55_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.030335 (rank : 40)
Query Neighborhood Hits	68	Target Neighborhood Hits	513	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CK5P2_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.013346 (rank : 57)
Query Neighborhood Hits	68	Target Neighborhood Hits	1433	Shared Neighborhood Hits	23
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

GP137_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.043361 (rank : 31)
Query Neighborhood Hits	68	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	Q14444, Q15074	Gene names	M11S1, GPIP137
Domain Architecture	No domain graphic available
Description	GPI-anchored protein p137 (p137GPI) (Membrane component chromosome 11 surface marker 1).

KLC1_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.013302 (rank : 58)
Query Neighborhood Hits	68	Target Neighborhood Hits	471	Shared Neighborhood Hits	13
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

RB6I2_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.011851 (rank : 60)
Query Neighborhood Hits	68	Target Neighborhood Hits	1584	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

ROCK2_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.003324 (rank : 72)
Query Neighborhood Hits	68	Target Neighborhood Hits	2073	Shared Neighborhood Hits	24
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

AFF4_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.024066 (rank : 47)
Query Neighborhood Hits	68	Target Neighborhood Hits	611	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

GOGB1_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.010374 (rank : 64)
Query Neighborhood Hits	68	Target Neighborhood Hits	2297	Shared Neighborhood Hits	37
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

IDLC_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.034112 (rank : 36)
Query Neighborhood Hits	68	Target Neighborhood Hits	348	Shared Neighborhood Hits	12
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

IDLC_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.035254 (rank : 34)
Query Neighborhood Hits	68	Target Neighborhood Hits	321	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

IF4G1_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.012991 (rank : 59)
Query Neighborhood Hits	68	Target Neighborhood Hits	534	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

PQBP1_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.031085 (rank : 39)
Query Neighborhood Hits	68	Target Neighborhood Hits	85	Shared Neighborhood Hits	10
SwissProt Accessions	O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4	Gene names	PQBP1, NPW38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

TP53B_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.019300 (rank : 50)
Query Neighborhood Hits	68	Target Neighborhood Hits	644	Shared Neighborhood Hits	14
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

AKA12_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.035904 (rank : 32)
Query Neighborhood Hits	68	Target Neighborhood Hits	825	Shared Neighborhood Hits	26
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

AR13B_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.017061 (rank : 52)
Query Neighborhood Hits	68	Target Neighborhood Hits	528	Shared Neighborhood Hits	17
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

IGB1B_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.026748 (rank : 44)
Query Neighborhood Hits	68	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZ29	Gene names	Igbp1b
Domain Architecture
Description	Immunoglobulin-binding protein 1b (CD79a-binding protein 1b) (Alpha 4- b protein) (Alpha4-b).

IPP2_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.031823 (rank : 38)
Query Neighborhood Hits	68	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

MY18A_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.006704 (rank : 68)
Query Neighborhood Hits	68	Target Neighborhood Hits	1929	Shared Neighborhood Hits	34
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PEG3_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.011101 (rank : 61)
Query Neighborhood Hits	68	Target Neighborhood Hits	1101	Shared Neighborhood Hits	30
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

SETD2_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.025382 (rank : 46)
Query Neighborhood Hits	68	Target Neighborhood Hits	412	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SMC2_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.009493 (rank : 65)
Query Neighborhood Hits	68	Target Neighborhood Hits	1131	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SPEG_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.001894 (rank : 73)
Query Neighborhood Hits	68	Target Neighborhood Hits	1959	Shared Neighborhood Hits	12
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZC313_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.051414 (rank : 26)
Query Neighborhood Hits	68	Target Neighborhood Hits	772	Shared Neighborhood Hits	35
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ADA30_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.006332 (rank : 71)
Query Neighborhood Hits	68	Target Neighborhood Hits	391	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

CF010_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.051445 (rank : 25)
Query Neighborhood Hits	68	Target Neighborhood Hits	329	Shared Neighborhood Hits	24
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

IRX2_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.017999 (rank : 51)
Query Neighborhood Hits	68	Target Neighborhood Hits	358	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

NASP_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.046538 (rank : 27)
Query Neighborhood Hits	68	Target Neighborhood Hits	709	Shared Neighborhood Hits	33
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

POT15_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.006546 (rank : 70)
Query Neighborhood Hits	68	Target Neighborhood Hits	893	Shared Neighborhood Hits	20
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

SV2C_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.007138 (rank : 67)
Query Neighborhood Hits	68	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q496J9, Q496K1, Q9UPU8	Gene names	SV2C, KIAA1054
Domain Architecture	No domain graphic available
Description	Synaptic vesicle glycoprotein 2C.

EFNB2_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.006697 (rank : 69)
Query Neighborhood Hits	68	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P52799	Gene names	EFNB2, EPLG5, HTKL, LERK5
Domain Architecture
Description	Ephrin-B2 precursor (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L).

IMB3_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.010744 (rank : 63)
Query Neighborhood Hits	68	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.010898 (rank : 62)
Query Neighborhood Hits	68	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

MDC1_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.015500 (rank : 55)
Query Neighborhood Hits	68	Target Neighborhood Hits	1446	Shared Neighborhood Hits	30
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

RAG2_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.016458 (rank : 54)
Query Neighborhood Hits	68	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	P55895, Q8TBL4	Gene names	RAG2
Domain Architecture
Description	V(D)J recombination-activating protein 2 (RAG-2).

TR150_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.043755 (rank : 29)
Query Neighborhood Hits	68	Target Neighborhood Hits	468	Shared Neighborhood Hits	26
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TS101_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.009139 (rank : 66)
Query Neighborhood Hits	68	Target Neighborhood Hits	312	Shared Neighborhood Hits	6
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

UBP8_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.014025 (rank : 56)
Query Neighborhood Hits	68	Target Neighborhood Hits	751	Shared Neighborhood Hits	37
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

NSBP1_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.059287 (rank : 20)
Query Neighborhood Hits	68	Target Neighborhood Hits	251	Shared Neighborhood Hits	34
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

PTMA_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.084193 (rank : 15)
Query Neighborhood Hits	68	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PTMA_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.074912 (rank : 16)
Query Neighborhood Hits	68	Target Neighborhood Hits	73	Shared Neighborhood Hits	15
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

PTMS_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.070509 (rank : 17)
Query Neighborhood Hits	68	Target Neighborhood Hits	111	Shared Neighborhood Hits	24
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

PTMS_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.067095 (rank : 18)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

Hits sorted by NC score

CALR_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	68
SwissProt Accessions	P14211	Gene names	Calr
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60).

CALR_HUMAN
NC score	0.993732 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	68	Target Neighborhood Hits	85	Shared Neighborhood Hits	52
SwissProt Accessions	P27797	Gene names	CALR, CRTC
Domain Architecture
Description	Calreticulin precursor (CRP55) (Calregulin) (HACBP) (ERp60) (grp60).

CALR3_HUMAN
NC score	0.962502 (rank : 3)	θ value	7.14227e-106 (rank : 3)
Query Neighborhood Hits	68	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q96L12, Q96LN3	Gene names	CALR3, CRT2
Domain Architecture
Description	Calreticulin-3 precursor (Calreticulin-2).

CALR3_MOUSE
NC score	0.959767 (rank : 4)	θ value	8.73085e-104 (rank : 4)
Query Neighborhood Hits	68	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D9Q6	Gene names	Calr3, Crt2
Domain Architecture
Description	Calreticulin-3 precursor (Calreticulin-2).

CALX_MOUSE
NC score	0.896774 (rank : 5)	θ value	2.56992e-63 (rank : 6)
Query Neighborhood Hits	68	Target Neighborhood Hits	76	Shared Neighborhood Hits	23
SwissProt Accessions	P35564	Gene names	Canx
Domain Architecture
Description	Calnexin precursor.

CALX_HUMAN
NC score	0.892789 (rank : 6)	θ value	2.17557e-62 (rank : 7)
Query Neighborhood Hits	68	Target Neighborhood Hits	96	Shared Neighborhood Hits	26
SwissProt Accessions	P27824	Gene names	CANX
Domain Architecture
Description	Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90).

CLGN_HUMAN
NC score	0.887215 (rank : 7)	θ value	3.47335e-60 (rank : 8)
Query Neighborhood Hits	68	Target Neighborhood Hits	111	Shared Neighborhood Hits	22
SwissProt Accessions	O14967	Gene names	CLGN
Domain Architecture
Description	Calmegin precursor.

CLGN_MOUSE
NC score	0.879937 (rank : 8)	θ value	1.6097e-65 (rank : 5)
Query Neighborhood Hits	68	Target Neighborhood Hits	142	Shared Neighborhood Hits	15
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

ERIC1_HUMAN
NC score	0.145073 (rank : 9)	θ value	0.00020696 (rank : 9)
Query Neighborhood Hits	68	Target Neighborhood Hits	364	Shared Neighborhood Hits	18
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

LEO1_MOUSE
NC score	0.099491 (rank : 10)	θ value	0.00228821 (rank : 10)
Query Neighborhood Hits	68	Target Neighborhood Hits	946	Shared Neighborhood Hits	36
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

NSBP1_MOUSE
NC score	0.098641 (rank : 11)	θ value	0.0563607 (rank : 14)
Query Neighborhood Hits	68	Target Neighborhood Hits	681	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

SEC63_MOUSE
NC score	0.093652 (rank : 12)	θ value	0.0113563 (rank : 12)
Query Neighborhood Hits	68	Target Neighborhood Hits	601	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_HUMAN
NC score	0.085223 (rank : 13)	θ value	0.0431538 (rank : 13)
Query Neighborhood Hits	68	Target Neighborhood Hits	586	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

LEO1_HUMAN
NC score	0.085137 (rank : 14)	θ value	0.0113563 (rank : 11)
Query Neighborhood Hits	68	Target Neighborhood Hits	958	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

PTMA_HUMAN
NC score	0.084193 (rank : 15)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	68	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PTMA_MOUSE
NC score	0.074912 (rank : 16)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	68	Target Neighborhood Hits	73	Shared Neighborhood Hits	15
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

PTMS_HUMAN
NC score	0.070509 (rank : 17)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	68	Target Neighborhood Hits	111	Shared Neighborhood Hits	24
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

PTMS_MOUSE
NC score	0.067095 (rank : 18)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

TCAL5_HUMAN
NC score	0.061586 (rank : 19)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	68	Target Neighborhood Hits	806	Shared Neighborhood Hits	31
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

NSBP1_HUMAN
NC score	0.059287 (rank : 20)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	68	Target Neighborhood Hits	251	Shared Neighborhood Hits	34
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

CC47_MOUSE
NC score	0.056243 (rank : 21)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	68	Target Neighborhood Hits	245	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

F10A1_HUMAN
NC score	0.055230 (rank : 22)	θ value	0.279714 (rank : 15)
Query Neighborhood Hits	68	Target Neighborhood Hits	312	Shared Neighborhood Hits	13
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

F10A5_HUMAN
NC score	0.054080 (rank : 23)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	68	Target Neighborhood Hits	277	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

GP137_MOUSE
NC score	0.052469 (rank : 24)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	68	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q60865, Q60758, Q61620	Gene names	M11s1, Gpiap, Gpiap1, Gpip137
Domain Architecture	No domain graphic available
Description	GPI-anchored protein p137 (p137GPI).

CF010_HUMAN
NC score	0.051445 (rank : 25)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	68	Target Neighborhood Hits	329	Shared Neighborhood Hits	24
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

ZC313_HUMAN
NC score	0.051414 (rank : 26)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	68	Target Neighborhood Hits	772	Shared Neighborhood Hits	35
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

NASP_HUMAN
NC score	0.046538 (rank : 27)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	68	Target Neighborhood Hits	709	Shared Neighborhood Hits	33
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

F10A4_HUMAN
NC score	0.045803 (rank : 28)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	68	Target Neighborhood Hits	249	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZP2	Gene names	FAM10A4
Domain Architecture	No domain graphic available
Description	Protein FAM10A4.

TR150_MOUSE
NC score	0.043755 (rank : 29)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	68	Target Neighborhood Hits	468	Shared Neighborhood Hits	26
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

SCG2_HUMAN
NC score	0.043469 (rank : 30)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	68	Target Neighborhood Hits	190	Shared Neighborhood Hits	7
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

GP137_HUMAN
NC score	0.043361 (rank : 31)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	68	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	Q14444, Q15074	Gene names	M11S1, GPIP137
Domain Architecture	No domain graphic available
Description	GPI-anchored protein p137 (p137GPI) (Membrane component chromosome 11 surface marker 1).

AKA12_HUMAN
NC score	0.035904 (rank : 32)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	68	Target Neighborhood Hits	825	Shared Neighborhood Hits	26
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

TXND2_HUMAN
NC score	0.035422 (rank : 33)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	68	Target Neighborhood Hits	793	Shared Neighborhood Hits	23
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

IDLC_MOUSE
NC score	0.035254 (rank : 34)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	68	Target Neighborhood Hits	321	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BVN8	Gene names	Dnali1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal).

LRRC6_HUMAN
NC score	0.034464 (rank : 35)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	68	Target Neighborhood Hits	181	Shared Neighborhood Hits	11
SwissProt Accessions	Q86X45, Q13648, Q4G183	Gene names	LRRC6, LRTP, TSLRP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 6 (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein).

IDLC_HUMAN
NC score	0.034112 (rank : 36)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	68	Target Neighborhood Hits	348	Shared Neighborhood Hits	12
SwissProt Accessions	O14645, Q5TGH0, Q7L0I5	Gene names	DNALI1
Domain Architecture	No domain graphic available
Description	Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28).

RPTN_HUMAN
NC score	0.032379 (rank : 37)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	68	Target Neighborhood Hits	406	Shared Neighborhood Hits	17
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

IPP2_MOUSE
NC score	0.031823 (rank : 38)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	68	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

PQBP1_HUMAN
NC score	0.031085 (rank : 39)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	68	Target Neighborhood Hits	85	Shared Neighborhood Hits	10
SwissProt Accessions	O60828, Q4VY25, Q4VY26, Q4VY27, Q4VY29, Q4VY30, Q4VY34, Q4VY35, Q4VY36, Q4VY37, Q4VY38, Q9GZP2, Q9GZU4, Q9GZZ4	Gene names	PQBP1, NPW38
Domain Architecture	No domain graphic available
Description	Polyglutamine-binding protein 1 (Polyglutamine tract-binding protein 1) (PQBP-1) (38 kDa nuclear protein containing a WW domain) (Npw38).

CCD55_HUMAN
NC score	0.030335 (rank : 40)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	68	Target Neighborhood Hits	513	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

NALP5_MOUSE
NC score	0.029539 (rank : 41)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	68	Target Neighborhood Hits	560	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

PHF20_HUMAN
NC score	0.027490 (rank : 42)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	68	Target Neighborhood Hits	394	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PPIG_HUMAN
NC score	0.026883 (rank : 43)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	68	Target Neighborhood Hits	670	Shared Neighborhood Hits	32
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

IGB1B_MOUSE
NC score	0.026748 (rank : 44)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	68	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZ29	Gene names	Igbp1b
Domain Architecture
Description	Immunoglobulin-binding protein 1b (CD79a-binding protein 1b) (Alpha 4- b protein) (Alpha4-b).

OSBL8_HUMAN
NC score	0.026162 (rank : 45)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	68	Target Neighborhood Hits	289	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

SETD2_HUMAN
NC score	0.025382 (rank : 46)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	68	Target Neighborhood Hits	412	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

AFF4_HUMAN
NC score	0.024066 (rank : 47)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	68	Target Neighborhood Hits	611	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

DMN_HUMAN
NC score	0.021100 (rank : 48)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	68	Target Neighborhood Hits	690	Shared Neighborhood Hits	22
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

ITSN1_HUMAN
NC score	0.019566 (rank : 49)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	68	Target Neighborhood Hits	1757	Shared Neighborhood Hits	29
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

TP53B_MOUSE
NC score	0.019300 (rank : 50)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	68	Target Neighborhood Hits	644	Shared Neighborhood Hits	14
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

IRX2_HUMAN
NC score	0.017999 (rank : 51)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	68	Target Neighborhood Hits	358	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

AR13B_HUMAN
NC score	0.017061 (rank : 52)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	68	Target Neighborhood Hits	528	Shared Neighborhood Hits	17
SwissProt Accessions	Q3SXY8, Q504W8	Gene names	ARL13B, ARL2L1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

ITSN1_MOUSE
NC score	0.016655 (rank : 53)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	68	Target Neighborhood Hits	1669	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

RAG2_HUMAN
NC score	0.016458 (rank : 54)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	68	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	P55895, Q8TBL4	Gene names	RAG2
Domain Architecture
Description	V(D)J recombination-activating protein 2 (RAG-2).

MDC1_HUMAN
NC score	0.015500 (rank : 55)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	68	Target Neighborhood Hits	1446	Shared Neighborhood Hits	30
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

UBP8_HUMAN
NC score	0.014025 (rank : 56)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	68	Target Neighborhood Hits	751	Shared Neighborhood Hits	37
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

CK5P2_HUMAN
NC score	0.013346 (rank : 57)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	68	Target Neighborhood Hits	1433	Shared Neighborhood Hits	23
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

KLC1_HUMAN
NC score	0.013302 (rank : 58)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	68	Target Neighborhood Hits	471	Shared Neighborhood Hits	13
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

IF4G1_MOUSE
NC score	0.012991 (rank : 59)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	68	Target Neighborhood Hits	534	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

RB6I2_HUMAN
NC score	0.011851 (rank : 60)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	68	Target Neighborhood Hits	1584	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

PEG3_MOUSE
NC score	0.011101 (rank : 61)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	68	Target Neighborhood Hits	1101	Shared Neighborhood Hits	30
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

IMB3_MOUSE
NC score	0.010898 (rank : 62)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	68	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_HUMAN
NC score	0.010744 (rank : 63)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	68	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

GOGB1_HUMAN
NC score	0.010374 (rank : 64)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	68	Target Neighborhood Hits	2297	Shared Neighborhood Hits	37
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SMC2_MOUSE
NC score	0.009493 (rank : 65)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	68	Target Neighborhood Hits	1131	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

TS101_MOUSE
NC score	0.009139 (rank : 66)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	68	Target Neighborhood Hits	312	Shared Neighborhood Hits	6
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

SV2C_HUMAN
NC score	0.007138 (rank : 67)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	68	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q496J9, Q496K1, Q9UPU8	Gene names	SV2C, KIAA1054
Domain Architecture	No domain graphic available
Description	Synaptic vesicle glycoprotein 2C.

MY18A_HUMAN
NC score	0.006704 (rank : 68)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	68	Target Neighborhood Hits	1929	Shared Neighborhood Hits	34
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

EFNB2_HUMAN
NC score	0.006697 (rank : 69)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	68	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P52799	Gene names	EFNB2, EPLG5, HTKL, LERK5
Domain Architecture
Description	Ephrin-B2 precursor (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L).

POT15_HUMAN
NC score	0.006546 (rank : 70)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	68	Target Neighborhood Hits	893	Shared Neighborhood Hits	20
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ADA30_HUMAN
NC score	0.006332 (rank : 71)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	68	Target Neighborhood Hits	391	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ROCK2_HUMAN
NC score	0.003324 (rank : 72)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	68	Target Neighborhood Hits	2073	Shared Neighborhood Hits	24
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

SPEG_MOUSE
NC score	0.001894 (rank : 73)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	68	Target Neighborhood Hits	1959	Shared Neighborhood Hits	12
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).