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Network neighborhood for query Sequence : PRPF3_HUMAN

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PRPF3_HUMAN
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PRPF3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).

PRPF3_MOUSE
θ value	0 (rank : 2)	NC score	0.994705 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	74	Shared Neighborhood Hits	58
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

SRRM1_HUMAN
θ value	0.0563607 (rank : 3)	NC score	0.095444 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	690	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	0.0563607 (rank : 4)	NC score	0.090421 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	966	Shared Neighborhood Hits	21
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ANKS1_MOUSE
θ value	0.0961366 (rank : 5)	NC score	0.036709 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	453	Shared Neighborhood Hits	8
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

PARD3_MOUSE
θ value	0.0961366 (rank : 6)	NC score	0.060471 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	290	Shared Neighborhood Hits	7
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

MKL1_MOUSE
θ value	0.21417 (rank : 7)	NC score	0.048857 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	667	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

CENPE_HUMAN
θ value	0.279714 (rank : 8)	NC score	0.025296 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	2060	Shared Neighborhood Hits	26
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

DYNA_HUMAN
θ value	0.47712 (rank : 9)	NC score	0.038087 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	1194	Shared Neighborhood Hits	20
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

MNDA_HUMAN
θ value	0.47712 (rank : 10)	NC score	0.056661 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	P41218	Gene names	MNDA
Domain Architecture
Description	Myeloid cell nuclear differentiation antigen.

MYH10_MOUSE
θ value	0.62314 (rank : 11)	NC score	0.022250 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	1612	Shared Neighborhood Hits	22
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

CACB2_HUMAN
θ value	0.813845 (rank : 12)	NC score	0.036765 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

CACB2_MOUSE
θ value	0.813845 (rank : 13)	NC score	0.037042 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

ENPL_HUMAN
θ value	0.813845 (rank : 14)	NC score	0.055397 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	P14625, Q96A97	Gene names	HSP90B1, TRA1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (gp96 homolog) (Tumor rejection antigen 1).

ENPL_MOUSE
θ value	0.813845 (rank : 15)	NC score	0.055461 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	P08113, P11427	Gene names	Hsp90b1, Tra-1, Tra1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (ERP99) (Polymorphic tumor rejection antigen 1) (Tumor rejection antigen gp96).

OSBL5_HUMAN
θ value	0.813845 (rank : 16)	NC score	0.050164 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

MAP1B_MOUSE
θ value	1.06291 (rank : 17)	NC score	0.031666 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	977	Shared Neighborhood Hits	14
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

CCD45_MOUSE
θ value	1.38821 (rank : 18)	NC score	0.045452 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	663	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

DHX29_HUMAN
θ value	1.38821 (rank : 19)	NC score	0.032257 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	144	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

IF2B_HUMAN
θ value	1.38821 (rank : 20)	NC score	0.081323 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	P20042, Q9BVU0, Q9UJE4	Gene names	EIF2S2, EIF2B
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

LAP2_MOUSE
θ value	1.38821 (rank : 21)	NC score	0.019070 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	482	Shared Neighborhood Hits	8
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

OSBL5_MOUSE
θ value	1.38821 (rank : 22)	NC score	0.047143 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

ASPX_MOUSE
θ value	1.81305 (rank : 23)	NC score	0.067013 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P50289, Q9DAM6	Gene names	Acrv1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1) (MSA- 63).

IF2B_MOUSE
θ value	1.81305 (rank : 24)	NC score	0.077393 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q99L45, Q9CSH6, Q9CT12	Gene names	Eif2s2
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

MITF_HUMAN
θ value	1.81305 (rank : 25)	NC score	0.049396 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

NKX24_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.022685 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	366	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2Z4	Gene names	NKX2-4, NKX2D
Domain Architecture
Description	Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D).

SCG3_MOUSE
θ value	1.81305 (rank : 27)	NC score	0.052199 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	P47867	Gene names	Scg3
Domain Architecture	No domain graphic available
Description	Secretogranin-3 precursor (Secretogranin III) (SgIII).

ANR26_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.020706 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	1614	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

GAK11_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.064663 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	409	Shared Neighborhood Hits	15
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.065020 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	374	Shared Neighborhood Hits	16
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK1_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.064652 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	268	Shared Neighborhood Hits	14
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.064159 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	406	Shared Neighborhood Hits	15
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK3_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.065280 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	182	Shared Neighborhood Hits	12
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.064717 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	415	Shared Neighborhood Hits	15
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK5_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.063477 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	429	Shared Neighborhood Hits	15
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

LMNB1_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.020132 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	714	Shared Neighborhood Hits	16
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

SF01_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.051358 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	287	Shared Neighborhood Hits	12
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.052371 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	240	Shared Neighborhood Hits	11
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

WDR63_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.054322 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWG1, Q96L72, Q96NU4	Gene names	WDR63
Domain Architecture	No domain graphic available
Description	WD repeat protein 63 (Testis development protein NYD-SP29).

GAK6_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.063381 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	392	Shared Neighborhood Hits	15
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GNDS_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.025266 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	201	Shared Neighborhood Hits	4
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

MITF_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.044805 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	115	Shared Neighborhood Hits	4
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MYH10_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.018987 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	1620	Shared Neighborhood Hits	23
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NKX24_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.018304 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	356	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQM3, Q9EQM4	Gene names	Nkx2-4, Nkx2d
Domain Architecture
Description	Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D).

PARD3_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.038531 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	312	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

DHX29_MOUSE
θ value	5.27518 (rank : 46)	NC score	0.023804 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PGC1, Q8BQJ4, Q8BT01, Q8C9B7, Q8C9H9	Gene names	Dhx29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29).

HIRP3_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.036249 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	323	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

NOP14_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.037269 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	573	Shared Neighborhood Hits	18
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NSD1_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.020889 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	472	Shared Neighborhood Hits	6
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

SEPR_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.017467 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q12884, O00199, Q86Z29, Q99998, Q9UID4	Gene names	FAP
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease) (170 kDa melanoma membrane-bound gelatinase).

ANR26_MOUSE
θ value	6.88961 (rank : 51)	NC score	0.017094 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	1554	Shared Neighborhood Hits	21
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

BCOR_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.020987 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	609	Shared Neighborhood Hits	10
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

INCE_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.021059 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	978	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

PEPL_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.016737 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	1141	Shared Neighborhood Hits	21
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

SLIT3_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.005172 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	700	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TIE2_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.000258 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	1204	Shared Neighborhood Hits	3
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

BPA1_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.014708 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	1477	Shared Neighborhood Hits	20
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CN155_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.020859 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	385	Shared Neighborhood Hits	12
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

DYNA_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.026258 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	1084	Shared Neighborhood Hits	18
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

GON4L_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.013706 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	555	Shared Neighborhood Hits	13
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

IF2P_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.022979 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	889	Shared Neighborhood Hits	19
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

PRKDC_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.014101 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

RPGR1_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.025645 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	713	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

USBP1_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.029675 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	188	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N6Y0, Q8NBX7, Q96KH3, Q9BYI8	Gene names	USHBP1, AIEBP, MCC2
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1) (MCC-2) (AIE-75 binding protein).

ZN291_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.024425 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	647	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

GAK10_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.055705 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	289	Shared Neighborhood Hits	14
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

Hits sorted by NC score

PRPF3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).

PRPF3_MOUSE
NC score	0.994705 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	74	Shared Neighborhood Hits	58
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

SRRM1_HUMAN
NC score	0.095444 (rank : 3)	θ value	0.0563607 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	690	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
NC score	0.090421 (rank : 4)	θ value	0.0563607 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	966	Shared Neighborhood Hits	21
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

IF2B_HUMAN
NC score	0.081323 (rank : 5)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	P20042, Q9BVU0, Q9UJE4	Gene names	EIF2S2, EIF2B
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

IF2B_MOUSE
NC score	0.077393 (rank : 6)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q99L45, Q9CSH6, Q9CT12	Gene names	Eif2s2
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

ASPX_MOUSE
NC score	0.067013 (rank : 7)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P50289, Q9DAM6	Gene names	Acrv1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1) (MSA- 63).

GAK3_HUMAN
NC score	0.065280 (rank : 8)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	182	Shared Neighborhood Hits	12
SwissProt Accessions	Q9YNA8	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(C19) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
NC score	0.065020 (rank : 9)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	374	Shared Neighborhood Hits	16
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
NC score	0.064717 (rank : 10)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	415	Shared Neighborhood Hits	15
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
NC score	0.064663 (rank : 11)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	409	Shared Neighborhood Hits	15
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK1_HUMAN
NC score	0.064652 (rank : 12)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	268	Shared Neighborhood Hits	14
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
NC score	0.064159 (rank : 13)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	406	Shared Neighborhood Hits	15
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK5_HUMAN
NC score	0.063477 (rank : 14)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	429	Shared Neighborhood Hits	15
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
NC score	0.063381 (rank : 15)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	392	Shared Neighborhood Hits	15
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PARD3_MOUSE
NC score	0.060471 (rank : 16)	θ value	0.0961366 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	290	Shared Neighborhood Hits	7
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

MNDA_HUMAN
NC score	0.056661 (rank : 17)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	P41218	Gene names	MNDA
Domain Architecture
Description	Myeloid cell nuclear differentiation antigen.

GAK10_HUMAN
NC score	0.055705 (rank : 18)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	289	Shared Neighborhood Hits	14
SwissProt Accessions	P87889, P10263, P10264, Q69385, Q9UKH6	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q33.3 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K10 Gag protein) (HERV-K107 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

ENPL_MOUSE
NC score	0.055461 (rank : 19)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	P08113, P11427	Gene names	Hsp90b1, Tra-1, Tra1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (ERP99) (Polymorphic tumor rejection antigen 1) (Tumor rejection antigen gp96).

ENPL_HUMAN
NC score	0.055397 (rank : 20)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	P14625, Q96A97	Gene names	HSP90B1, TRA1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (gp96 homolog) (Tumor rejection antigen 1).

WDR63_HUMAN
NC score	0.054322 (rank : 21)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWG1, Q96L72, Q96NU4	Gene names	WDR63
Domain Architecture	No domain graphic available
Description	WD repeat protein 63 (Testis development protein NYD-SP29).

SF01_MOUSE
NC score	0.052371 (rank : 22)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	240	Shared Neighborhood Hits	11
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SCG3_MOUSE
NC score	0.052199 (rank : 23)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	P47867	Gene names	Scg3
Domain Architecture	No domain graphic available
Description	Secretogranin-3 precursor (Secretogranin III) (SgIII).

SF01_HUMAN
NC score	0.051358 (rank : 24)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	287	Shared Neighborhood Hits	12
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

OSBL5_HUMAN
NC score	0.050164 (rank : 25)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

MITF_HUMAN
NC score	0.049396 (rank : 26)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MKL1_MOUSE
NC score	0.048857 (rank : 27)	θ value	0.21417 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	667	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

OSBL5_MOUSE
NC score	0.047143 (rank : 28)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

CCD45_MOUSE
NC score	0.045452 (rank : 29)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	663	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

MITF_MOUSE
NC score	0.044805 (rank : 30)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	115	Shared Neighborhood Hits	4
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

PARD3_HUMAN
NC score	0.038531 (rank : 31)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	312	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

DYNA_HUMAN
NC score	0.038087 (rank : 32)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	1194	Shared Neighborhood Hits	20
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

NOP14_HUMAN
NC score	0.037269 (rank : 33)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	573	Shared Neighborhood Hits	18
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

CACB2_MOUSE
NC score	0.037042 (rank : 34)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CC27, Q8C5J5, Q9CTQ6	Gene names	Cacnb2, Cacnlb2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2).

CACB2_HUMAN
NC score	0.036765 (rank : 35)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q08289, O00304, Q8WX81, Q96NZ3, Q96NZ4, Q96NZ5, Q9BWU2, Q9HD32, Q9Y340, Q9Y341	Gene names	CACNB2, CACNLB2, MYSB
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB).

ANKS1_MOUSE
NC score	0.036709 (rank : 36)	θ value	0.0961366 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	453	Shared Neighborhood Hits	8
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

HIRP3_HUMAN
NC score	0.036249 (rank : 37)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	323	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

DHX29_HUMAN
NC score	0.032257 (rank : 38)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	144	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z478, O75549, Q63HN0, Q63HN3, Q8IWW2, Q8N3A1, Q9UMH2	Gene names	DHX29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29) (Nucleic acid helicase DDXx).

MAP1B_MOUSE
NC score	0.031666 (rank : 39)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	977	Shared Neighborhood Hits	14
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

USBP1_HUMAN
NC score	0.029675 (rank : 40)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	188	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N6Y0, Q8NBX7, Q96KH3, Q9BYI8	Gene names	USHBP1, AIEBP, MCC2
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1) (MCC-2) (AIE-75 binding protein).

DYNA_MOUSE
NC score	0.026258 (rank : 41)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	1084	Shared Neighborhood Hits	18
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

RPGR1_MOUSE
NC score	0.025645 (rank : 42)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	713	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

CENPE_HUMAN
NC score	0.025296 (rank : 43)	θ value	0.279714 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	2060	Shared Neighborhood Hits	26
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

GNDS_HUMAN
NC score	0.025266 (rank : 44)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	201	Shared Neighborhood Hits	4
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

ZN291_HUMAN
NC score	0.024425 (rank : 45)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	647	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

DHX29_MOUSE
NC score	0.023804 (rank : 46)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PGC1, Q8BQJ4, Q8BT01, Q8C9B7, Q8C9H9	Gene names	Dhx29
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX29 (EC 3.6.1.-) (DEAH box protein 29).

IF2P_HUMAN
NC score	0.022979 (rank : 47)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	889	Shared Neighborhood Hits	19
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

NKX24_HUMAN
NC score	0.022685 (rank : 48)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	366	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2Z4	Gene names	NKX2-4, NKX2D
Domain Architecture
Description	Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D).

MYH10_MOUSE
NC score	0.022250 (rank : 49)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	1612	Shared Neighborhood Hits	22
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

INCE_HUMAN
NC score	0.021059 (rank : 50)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	978	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

BCOR_HUMAN
NC score	0.020987 (rank : 51)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	609	Shared Neighborhood Hits	10
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

NSD1_MOUSE
NC score	0.020889 (rank : 52)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	472	Shared Neighborhood Hits	6
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

CN155_HUMAN
NC score	0.020859 (rank : 53)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	385	Shared Neighborhood Hits	12
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

ANR26_HUMAN
NC score	0.020706 (rank : 54)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	1614	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

LMNB1_HUMAN
NC score	0.020132 (rank : 55)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	714	Shared Neighborhood Hits	16
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

LAP2_MOUSE
NC score	0.019070 (rank : 56)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	482	Shared Neighborhood Hits	8
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

MYH10_HUMAN
NC score	0.018987 (rank : 57)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	1620	Shared Neighborhood Hits	23
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NKX24_MOUSE
NC score	0.018304 (rank : 58)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	356	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQM3, Q9EQM4	Gene names	Nkx2-4, Nkx2d
Domain Architecture
Description	Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D).

SEPR_HUMAN
NC score	0.017467 (rank : 59)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q12884, O00199, Q86Z29, Q99998, Q9UID4	Gene names	FAP
Domain Architecture
Description	Seprase (EC 3.4.21.-) (Fibroblast activation protein alpha) (Integral membrane serine protease) (170 kDa melanoma membrane-bound gelatinase).

ANR26_MOUSE
NC score	0.017094 (rank : 60)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	1554	Shared Neighborhood Hits	21
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

PEPL_HUMAN
NC score	0.016737 (rank : 61)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	1141	Shared Neighborhood Hits	21
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

BPA1_MOUSE
NC score	0.014708 (rank : 62)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	1477	Shared Neighborhood Hits	20
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PRKDC_HUMAN
NC score	0.014101 (rank : 63)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

GON4L_HUMAN
NC score	0.013706 (rank : 64)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	555	Shared Neighborhood Hits	13
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

SLIT3_MOUSE
NC score	0.005172 (rank : 65)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	700	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TIE2_MOUSE
NC score	0.000258 (rank : 66)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	1204	Shared Neighborhood Hits	3
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).