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Network neighborhood for query Sequence : ENPL_MOUSE

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ENPL_MOUSE
SwissProt Accessions	P08113, P11427	Gene names	Hsp90b1, Tra-1, Tra1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (ERP99) (Polymorphic tumor rejection antigen 1) (Tumor rejection antigen gp96).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ENPL_HUMAN
θ value	0 (rank : 1)	NC score	0.995443 (rank : 2)
Query Neighborhood Hits	78	Target Neighborhood Hits	68	Shared Neighborhood Hits	52
SwissProt Accessions	P14625, Q96A97	Gene names	HSP90B1, TRA1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (gp96 homolog) (Tumor rejection antigen 1).

ENPL_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	78
SwissProt Accessions	P08113, P11427	Gene names	Hsp90b1, Tra-1, Tra1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (ERP99) (Polymorphic tumor rejection antigen 1) (Tumor rejection antigen gp96).

HS90B_MOUSE
θ value	6.90186e-109 (rank : 3)	NC score	0.931581 (rank : 4)
Query Neighborhood Hits	78	Target Neighborhood Hits	98	Shared Neighborhood Hits	15
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

HS90B_HUMAN
θ value	2.89973e-107 (rank : 4)	NC score	0.931922 (rank : 3)
Query Neighborhood Hits	78	Target Neighborhood Hits	98	Shared Neighborhood Hits	15
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

HS90A_HUMAN
θ value	1.14028e-103 (rank : 5)	NC score	0.929758 (rank : 5)
Query Neighborhood Hits	78	Target Neighborhood Hits	144	Shared Neighborhood Hits	25
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

HS90A_MOUSE
θ value	1.48926e-103 (rank : 6)	NC score	0.923573 (rank : 6)
Query Neighborhood Hits	78	Target Neighborhood Hits	155	Shared Neighborhood Hits	26
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

TRAP1_HUMAN
θ value	2.30828e-88 (rank : 7)	NC score	0.919875 (rank : 7)
Query Neighborhood Hits	78	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q12931, O43642, O75235, Q9UHL5	Gene names	TRAP1, HSP75
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

TRAP1_MOUSE
θ value	1.49618e-87 (rank : 8)	NC score	0.918442 (rank : 8)
Query Neighborhood Hits	78	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CQN1, Q542I4	Gene names	Trap1
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

CENPE_HUMAN
θ value	0.0431538 (rank : 9)	NC score	0.027772 (rank : 41)
Query Neighborhood Hits	78	Target Neighborhood Hits	2060	Shared Neighborhood Hits	39
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

MY18A_HUMAN
θ value	0.0736092 (rank : 10)	NC score	0.025983 (rank : 49)
Query Neighborhood Hits	78	Target Neighborhood Hits	1929	Shared Neighborhood Hits	38
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
θ value	0.0736092 (rank : 11)	NC score	0.027984 (rank : 39)
Query Neighborhood Hits	78	Target Neighborhood Hits	1989	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

LEO1_MOUSE
θ value	0.279714 (rank : 12)	NC score	0.046295 (rank : 17)
Query Neighborhood Hits	78	Target Neighborhood Hits	946	Shared Neighborhood Hits	31
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MYO3A_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.009068 (rank : 74)
Query Neighborhood Hits	78	Target Neighborhood Hits	1033	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

GCC2_MOUSE
θ value	0.365318 (rank : 14)	NC score	0.026577 (rank : 45)
Query Neighborhood Hits	78	Target Neighborhood Hits	1619	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

PK2L2_MOUSE
θ value	0.365318 (rank : 15)	NC score	0.041813 (rank : 20)
Query Neighborhood Hits	78	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

DCJ11_HUMAN
θ value	0.47712 (rank : 16)	NC score	0.035405 (rank : 28)
Query Neighborhood Hits	78	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NVH1, Q4VWF5, Q5VZN0, Q6PK20, Q6PK70, Q8NDM2, Q96CL7	Gene names	DNAJC11
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 11.

TPR_HUMAN
θ value	0.47712 (rank : 17)	NC score	0.027805 (rank : 40)
Query Neighborhood Hits	78	Target Neighborhood Hits	1921	Shared Neighborhood Hits	39
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

FMN1A_MOUSE
θ value	0.62314 (rank : 18)	NC score	0.036626 (rank : 24)
Query Neighborhood Hits	78	Target Neighborhood Hits	423	Shared Neighborhood Hits	8
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	0.62314 (rank : 19)	NC score	0.035578 (rank : 27)
Query Neighborhood Hits	78	Target Neighborhood Hits	447	Shared Neighborhood Hits	11
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

LYST_HUMAN
θ value	0.62314 (rank : 20)	NC score	0.027468 (rank : 42)
Query Neighborhood Hits	78	Target Neighborhood Hits	324	Shared Neighborhood Hits	10
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

LYST_MOUSE
θ value	0.62314 (rank : 21)	NC score	0.027321 (rank : 43)
Query Neighborhood Hits	78	Target Neighborhood Hits	286	Shared Neighborhood Hits	4
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

FA61B_HUMAN
θ value	0.813845 (rank : 22)	NC score	0.048138 (rank : 16)
Query Neighborhood Hits	78	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BX40, Q6PFW8, Q96LH8	Gene names	FAM61B, C20orf40
Domain Architecture	No domain graphic available
Description	Protein FAM61B.

PRPF3_HUMAN
θ value	0.813845 (rank : 23)	NC score	0.055461 (rank : 12)
Query Neighborhood Hits	78	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).

SACS_MOUSE
θ value	0.813845 (rank : 24)	NC score	0.043053 (rank : 19)
Query Neighborhood Hits	78	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLC8	Gene names	Sacs
Domain Architecture
Description	Sacsin.

TCAL3_HUMAN
θ value	0.813845 (rank : 25)	NC score	0.040476 (rank : 21)
Query Neighborhood Hits	78	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

ADA30_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.018526 (rank : 64)
Query Neighborhood Hits	78	Target Neighborhood Hits	391	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ANR26_HUMAN
θ value	1.06291 (rank : 27)	NC score	0.023906 (rank : 51)
Query Neighborhood Hits	78	Target Neighborhood Hits	1614	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CS029_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.052646 (rank : 14)
Query Neighborhood Hits	78	Target Neighborhood Hits	329	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

HMMR_MOUSE
θ value	1.38821 (rank : 29)	NC score	0.022123 (rank : 58)
Query Neighborhood Hits	78	Target Neighborhood Hits	1178	Shared Neighborhood Hits	30
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

PK2L2_HUMAN
θ value	1.38821 (rank : 30)	NC score	0.034047 (rank : 29)
Query Neighborhood Hits	78	Target Neighborhood Hits	90	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PRPF3_MOUSE
θ value	1.38821 (rank : 31)	NC score	0.050850 (rank : 15)
Query Neighborhood Hits	78	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

PSIP1_MOUSE
θ value	1.38821 (rank : 32)	NC score	0.026831 (rank : 44)
Query Neighborhood Hits	78	Target Neighborhood Hits	313	Shared Neighborhood Hits	21
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

CDN1C_MOUSE
θ value	1.81305 (rank : 33)	NC score	0.026007 (rank : 48)
Query Neighborhood Hits	78	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

LRC45_MOUSE
θ value	1.81305 (rank : 34)	NC score	0.026060 (rank : 47)
Query Neighborhood Hits	78	Target Neighborhood Hits	959	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

MAP1B_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.032141 (rank : 32)
Query Neighborhood Hits	78	Target Neighborhood Hits	903	Shared Neighborhood Hits	32
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

NBN_HUMAN
θ value	1.81305 (rank : 36)	NC score	0.033964 (rank : 31)
Query Neighborhood Hits	78	Target Neighborhood Hits	226	Shared Neighborhood Hits	10
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

TCAL5_HUMAN
θ value	1.81305 (rank : 37)	NC score	0.036469 (rank : 25)
Query Neighborhood Hits	78	Target Neighborhood Hits	806	Shared Neighborhood Hits	25
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

CP135_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.021149 (rank : 59)
Query Neighborhood Hits	78	Target Neighborhood Hits	1278	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

KNTC2_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.034005 (rank : 30)
Query Neighborhood Hits	78	Target Neighborhood Hits	692	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

NALP5_MOUSE
θ value	2.36792 (rank : 40)	NC score	0.013479 (rank : 68)
Query Neighborhood Hits	78	Target Neighborhood Hits	560	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

SACS_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.037542 (rank : 22)
Query Neighborhood Hits	78	Target Neighborhood Hits	128	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZJ4, O94835	Gene names	SACS, KIAA0730
Domain Architecture
Description	Sacsin.

CCD91_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.029511 (rank : 37)
Query Neighborhood Hits	78	Target Neighborhood Hits	868	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

LEO1_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.044890 (rank : 18)
Query Neighborhood Hits	78	Target Neighborhood Hits	958	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

PTHR2_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.011075 (rank : 71)
Query Neighborhood Hits	78	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q91V95	Gene names	Pthr2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

CAD23_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.006592 (rank : 78)
Query Neighborhood Hits	78	Target Neighborhood Hits	208	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

FA61B_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.035744 (rank : 26)
Query Neighborhood Hits	78	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CGC4	Gene names	Fam61b
Domain Architecture	No domain graphic available
Description	Protein FAM61B.

NIN_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.030140 (rank : 36)
Query Neighborhood Hits	78	Target Neighborhood Hits	1376	Shared Neighborhood Hits	29
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

RSF1_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.031460 (rank : 34)
Query Neighborhood Hits	78	Target Neighborhood Hits	539	Shared Neighborhood Hits	31
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SEC63_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.076256 (rank : 10)
Query Neighborhood Hits	78	Target Neighborhood Hits	586	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

ZN292_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.009349 (rank : 73)
Query Neighborhood Hits	78	Target Neighborhood Hits	918	Shared Neighborhood Hits	14
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

CAD23_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.006145 (rank : 79)
Query Neighborhood Hits	78	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CTGE5_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.022837 (rank : 55)
Query Neighborhood Hits	78	Target Neighborhood Hits	928	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

DCJ11_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.023360 (rank : 53)
Query Neighborhood Hits	78	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q5U458, Q8BP83, Q8C1Z4, Q8C6U5	Gene names	Dnajc11
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 11.

EEA1_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.019146 (rank : 63)
Query Neighborhood Hits	78	Target Neighborhood Hits	1796	Shared Neighborhood Hits	33
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

GOGA4_MOUSE
θ value	5.27518 (rank : 55)	NC score	0.028391 (rank : 38)
Query Neighborhood Hits	78	Target Neighborhood Hits	1939	Shared Neighborhood Hits	44
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

KNTC2_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.030865 (rank : 35)
Query Neighborhood Hits	78	Target Neighborhood Hits	673	Shared Neighborhood Hits	28
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

LN28A_MOUSE
θ value	5.27518 (rank : 57)	NC score	0.018328 (rank : 65)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K3Y3, Q6NV62	Gene names	Lin28, Lin28a, Tex17
Domain Architecture	No domain graphic available
Description	Lin-28 homolog A (Testis-expressed protein 17).

RBCC1_MOUSE
θ value	5.27518 (rank : 58)	NC score	0.022653 (rank : 57)
Query Neighborhood Hits	78	Target Neighborhood Hits	1048	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

SPRL1_MOUSE
θ value	5.27518 (rank : 59)	NC score	0.020873 (rank : 60)
Query Neighborhood Hits	78	Target Neighborhood Hits	403	Shared Neighborhood Hits	21
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TXND2_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.031638 (rank : 33)
Query Neighborhood Hits	78	Target Neighborhood Hits	828	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

AN30A_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.023569 (rank : 52)
Query Neighborhood Hits	78	Target Neighborhood Hits	1119	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

CCD41_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.020638 (rank : 61)
Query Neighborhood Hits	78	Target Neighborhood Hits	1139	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

GEMI_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.016120 (rank : 66)
Query Neighborhood Hits	78	Target Neighborhood Hits	192	Shared Neighborhood Hits	8
SwissProt Accessions	O75496, Q9H1Z1	Gene names	GMNN
Domain Architecture
Description	Geminin.

GOGA4_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.022662 (rank : 56)
Query Neighborhood Hits	78	Target Neighborhood Hits	2034	Shared Neighborhood Hits	43
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MIB2_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.005881 (rank : 80)
Query Neighborhood Hits	78	Target Neighborhood Hits	438	Shared Neighborhood Hits	5
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

PKHA5_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.012737 (rank : 69)
Query Neighborhood Hits	78	Target Neighborhood Hits	455	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

SMAD3_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.007699 (rank : 76)
Query Neighborhood Hits	78	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	P84022, O09064, O09144, O14510, O35273, Q92940, Q93002, Q9GKR4	Gene names	SMAD3, MADH3
Domain Architecture
Description	Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against DPP homolog 3) (Mad3) (hMAD-3) (JV15-2) (hSMAD3).

SMAD3_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.007699 (rank : 77)
Query Neighborhood Hits	78	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BUN5, O09064, O09144, O14510, O35273, Q8BX84, Q92940, Q93002, Q9GKR4	Gene names	Smad3, Madh3
Domain Architecture
Description	Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against DPP homolog 3) (Mad3) (mMad3).

AL2SB_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.023071 (rank : 54)
Query Neighborhood Hits	78	Target Neighborhood Hits	294	Shared Neighborhood Hits	18
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

CALX_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.008516 (rank : 75)
Query Neighborhood Hits	78	Target Neighborhood Hits	96	Shared Neighborhood Hits	11
SwissProt Accessions	P27824	Gene names	CANX
Domain Architecture
Description	Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90).

CC47_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.019526 (rank : 62)
Query Neighborhood Hits	78	Target Neighborhood Hits	245	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

CS029_MOUSE
θ value	8.99809 (rank : 72)	NC score	0.037125 (rank : 23)
Query Neighborhood Hits	78	Target Neighborhood Hits	201	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

MDN1_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.026133 (rank : 46)
Query Neighborhood Hits	78	Target Neighborhood Hits	662	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

RMI1_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.009440 (rank : 72)
Query Neighborhood Hits	78	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H9A7, Q5SQG8, Q5SQG9, Q6P1Q4, Q6PI89, Q7Z6L6	Gene names	RMI1, C9orf76
Domain Architecture	No domain graphic available
Description	Protein RMI1 homolog.

RT27_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.013993 (rank : 67)
Query Neighborhood Hits	78	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q92552	Gene names	MRPS27, KIAA0264
Domain Architecture	No domain graphic available
Description	Mitochondrial 28S ribosomal protein S27 (S27mt) (MRP-S27).

SCG1_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.024095 (rank : 50)
Query Neighborhood Hits	78	Target Neighborhood Hits	156	Shared Neighborhood Hits	12
SwissProt Accessions	P05060, Q9BQV6, Q9UJA6	Gene names	CHGB, SCG1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB) [Contains: GAWK peptide; CCB peptide].

SEC63_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.068097 (rank : 11)
Query Neighborhood Hits	78	Target Neighborhood Hits	601	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

ZN638_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.011552 (rank : 70)
Query Neighborhood Hits	78	Target Neighborhood Hits	343	Shared Neighborhood Hits	13
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

HSF2B_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.092209 (rank : 9)
Query Neighborhood Hits	78	Target Neighborhood Hits	104	Shared Neighborhood Hits	11
SwissProt Accessions	O75031	Gene names	HSF2BP
Domain Architecture	No domain graphic available
Description	Heat shock factor 2-binding protein.

PRI1_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.054833 (rank : 13)
Query Neighborhood Hits	78	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	P20664	Gene names	Prim1
Domain Architecture
Description	DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49).

Hits sorted by NC score

ENPL_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	78
SwissProt Accessions	P08113, P11427	Gene names	Hsp90b1, Tra-1, Tra1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (ERP99) (Polymorphic tumor rejection antigen 1) (Tumor rejection antigen gp96).

ENPL_HUMAN
NC score	0.995443 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	78	Target Neighborhood Hits	68	Shared Neighborhood Hits	52
SwissProt Accessions	P14625, Q96A97	Gene names	HSP90B1, TRA1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (gp96 homolog) (Tumor rejection antigen 1).

HS90B_HUMAN
NC score	0.931922 (rank : 3)	θ value	2.89973e-107 (rank : 4)
Query Neighborhood Hits	78	Target Neighborhood Hits	98	Shared Neighborhood Hits	15
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

HS90B_MOUSE
NC score	0.931581 (rank : 4)	θ value	6.90186e-109 (rank : 3)
Query Neighborhood Hits	78	Target Neighborhood Hits	98	Shared Neighborhood Hits	15
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

HS90A_HUMAN
NC score	0.929758 (rank : 5)	θ value	1.14028e-103 (rank : 5)
Query Neighborhood Hits	78	Target Neighborhood Hits	144	Shared Neighborhood Hits	25
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

HS90A_MOUSE
NC score	0.923573 (rank : 6)	θ value	1.48926e-103 (rank : 6)
Query Neighborhood Hits	78	Target Neighborhood Hits	155	Shared Neighborhood Hits	26
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

TRAP1_HUMAN
NC score	0.919875 (rank : 7)	θ value	2.30828e-88 (rank : 7)
Query Neighborhood Hits	78	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q12931, O43642, O75235, Q9UHL5	Gene names	TRAP1, HSP75
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

TRAP1_MOUSE
NC score	0.918442 (rank : 8)	θ value	1.49618e-87 (rank : 8)
Query Neighborhood Hits	78	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CQN1, Q542I4	Gene names	Trap1
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

HSF2B_HUMAN
NC score	0.092209 (rank : 9)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	78	Target Neighborhood Hits	104	Shared Neighborhood Hits	11
SwissProt Accessions	O75031	Gene names	HSF2BP
Domain Architecture	No domain graphic available
Description	Heat shock factor 2-binding protein.

SEC63_HUMAN
NC score	0.076256 (rank : 10)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	78	Target Neighborhood Hits	586	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_MOUSE
NC score	0.068097 (rank : 11)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	78	Target Neighborhood Hits	601	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

PRPF3_HUMAN
NC score	0.055461 (rank : 12)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	78	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).

PRI1_MOUSE
NC score	0.054833 (rank : 13)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	78	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	P20664	Gene names	Prim1
Domain Architecture
Description	DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49).

CS029_HUMAN
NC score	0.052646 (rank : 14)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	78	Target Neighborhood Hits	329	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

PRPF3_MOUSE
NC score	0.050850 (rank : 15)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	78	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

FA61B_HUMAN
NC score	0.048138 (rank : 16)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	78	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BX40, Q6PFW8, Q96LH8	Gene names	FAM61B, C20orf40
Domain Architecture	No domain graphic available
Description	Protein FAM61B.

LEO1_MOUSE
NC score	0.046295 (rank : 17)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	78	Target Neighborhood Hits	946	Shared Neighborhood Hits	31
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
NC score	0.044890 (rank : 18)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	78	Target Neighborhood Hits	958	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

SACS_MOUSE
NC score	0.043053 (rank : 19)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	78	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLC8	Gene names	Sacs
Domain Architecture
Description	Sacsin.

PK2L2_MOUSE
NC score	0.041813 (rank : 20)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	78	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

TCAL3_HUMAN
NC score	0.040476 (rank : 21)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	78	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

SACS_HUMAN
NC score	0.037542 (rank : 22)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	78	Target Neighborhood Hits	128	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZJ4, O94835	Gene names	SACS, KIAA0730
Domain Architecture
Description	Sacsin.

CS029_MOUSE
NC score	0.037125 (rank : 23)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	78	Target Neighborhood Hits	201	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

FMN1A_MOUSE
NC score	0.036626 (rank : 24)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	78	Target Neighborhood Hits	423	Shared Neighborhood Hits	8
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

TCAL5_HUMAN
NC score	0.036469 (rank : 25)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	78	Target Neighborhood Hits	806	Shared Neighborhood Hits	25
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

FA61B_MOUSE
NC score	0.035744 (rank : 26)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	78	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CGC4	Gene names	Fam61b
Domain Architecture	No domain graphic available
Description	Protein FAM61B.

FMN1B_MOUSE
NC score	0.035578 (rank : 27)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	78	Target Neighborhood Hits	447	Shared Neighborhood Hits	11
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

DCJ11_HUMAN
NC score	0.035405 (rank : 28)	θ value	0.47712 (rank : 16)
Query Neighborhood Hits	78	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NVH1, Q4VWF5, Q5VZN0, Q6PK20, Q6PK70, Q8NDM2, Q96CL7	Gene names	DNAJC11
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 11.

PK2L2_HUMAN
NC score	0.034047 (rank : 29)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	78	Target Neighborhood Hits	90	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

KNTC2_MOUSE
NC score	0.034005 (rank : 30)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	78	Target Neighborhood Hits	692	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

NBN_HUMAN
NC score	0.033964 (rank : 31)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	78	Target Neighborhood Hits	226	Shared Neighborhood Hits	10
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

MAP1B_HUMAN
NC score	0.032141 (rank : 32)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	78	Target Neighborhood Hits	903	Shared Neighborhood Hits	32
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

TXND2_MOUSE
NC score	0.031638 (rank : 33)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	78	Target Neighborhood Hits	828	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

RSF1_HUMAN
NC score	0.031460 (rank : 34)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	78	Target Neighborhood Hits	539	Shared Neighborhood Hits	31
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

KNTC2_HUMAN
NC score	0.030865 (rank : 35)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	78	Target Neighborhood Hits	673	Shared Neighborhood Hits	28
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

NIN_MOUSE
NC score	0.030140 (rank : 36)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	78	Target Neighborhood Hits	1376	Shared Neighborhood Hits	29
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

CCD91_HUMAN
NC score	0.029511 (rank : 37)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	78	Target Neighborhood Hits	868	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

GOGA4_MOUSE
NC score	0.028391 (rank : 38)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	78	Target Neighborhood Hits	1939	Shared Neighborhood Hits	44
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MY18A_MOUSE
NC score	0.027984 (rank : 39)	θ value	0.0736092 (rank : 11)
Query Neighborhood Hits	78	Target Neighborhood Hits	1989	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TPR_HUMAN
NC score	0.027805 (rank : 40)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	78	Target Neighborhood Hits	1921	Shared Neighborhood Hits	39
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CENPE_HUMAN
NC score	0.027772 (rank : 41)	θ value	0.0431538 (rank : 9)
Query Neighborhood Hits	78	Target Neighborhood Hits	2060	Shared Neighborhood Hits	39
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

LYST_HUMAN
NC score	0.027468 (rank : 42)	θ value	0.62314 (rank : 20)
Query Neighborhood Hits	78	Target Neighborhood Hits	324	Shared Neighborhood Hits	10
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

LYST_MOUSE
NC score	0.027321 (rank : 43)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	78	Target Neighborhood Hits	286	Shared Neighborhood Hits	4
SwissProt Accessions	P97412, Q62403, Q8VBS6	Gene names	Lyst, Bg, Chs1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog).

PSIP1_MOUSE
NC score	0.026831 (rank : 44)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	78	Target Neighborhood Hits	313	Shared Neighborhood Hits	21
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

GCC2_MOUSE
NC score	0.026577 (rank : 45)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	78	Target Neighborhood Hits	1619	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

MDN1_HUMAN
NC score	0.026133 (rank : 46)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	78	Target Neighborhood Hits	662	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

LRC45_MOUSE
NC score	0.026060 (rank : 47)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	78	Target Neighborhood Hits	959	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

CDN1C_MOUSE
NC score	0.026007 (rank : 48)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	78	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

MY18A_HUMAN
NC score	0.025983 (rank : 49)	θ value	0.0736092 (rank : 10)
Query Neighborhood Hits	78	Target Neighborhood Hits	1929	Shared Neighborhood Hits	38
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SCG1_HUMAN
NC score	0.024095 (rank : 50)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	78	Target Neighborhood Hits	156	Shared Neighborhood Hits	12
SwissProt Accessions	P05060, Q9BQV6, Q9UJA6	Gene names	CHGB, SCG1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB) [Contains: GAWK peptide; CCB peptide].

ANR26_HUMAN
NC score	0.023906 (rank : 51)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	78	Target Neighborhood Hits	1614	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

AN30A_HUMAN
NC score	0.023569 (rank : 52)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	78	Target Neighborhood Hits	1119	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

DCJ11_MOUSE
NC score	0.023360 (rank : 53)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	78	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q5U458, Q8BP83, Q8C1Z4, Q8C6U5	Gene names	Dnajc11
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 11.

AL2SB_HUMAN
NC score	0.023071 (rank : 54)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	78	Target Neighborhood Hits	294	Shared Neighborhood Hits	18
SwissProt Accessions	Q96Q35	Gene names	ALS2CR12
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein.

CTGE5_MOUSE
NC score	0.022837 (rank : 55)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	78	Target Neighborhood Hits	928	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

GOGA4_HUMAN
NC score	0.022662 (rank : 56)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	78	Target Neighborhood Hits	2034	Shared Neighborhood Hits	43
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

RBCC1_MOUSE
NC score	0.022653 (rank : 57)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	78	Target Neighborhood Hits	1048	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

HMMR_MOUSE
NC score	0.022123 (rank : 58)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	78	Target Neighborhood Hits	1178	Shared Neighborhood Hits	30
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

CP135_MOUSE
NC score	0.021149 (rank : 59)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	78	Target Neighborhood Hits	1278	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

SPRL1_MOUSE
NC score	0.020873 (rank : 60)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	78	Target Neighborhood Hits	403	Shared Neighborhood Hits	21
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

CCD41_HUMAN
NC score	0.020638 (rank : 61)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	78	Target Neighborhood Hits	1139	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CC47_MOUSE
NC score	0.019526 (rank : 62)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	78	Target Neighborhood Hits	245	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

EEA1_HUMAN
NC score	0.019146 (rank : 63)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	78	Target Neighborhood Hits	1796	Shared Neighborhood Hits	33
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

ADA30_HUMAN
NC score	0.018526 (rank : 64)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	78	Target Neighborhood Hits	391	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

LN28A_MOUSE
NC score	0.018328 (rank : 65)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K3Y3, Q6NV62	Gene names	Lin28, Lin28a, Tex17
Domain Architecture	No domain graphic available
Description	Lin-28 homolog A (Testis-expressed protein 17).

GEMI_HUMAN
NC score	0.016120 (rank : 66)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	78	Target Neighborhood Hits	192	Shared Neighborhood Hits	8
SwissProt Accessions	O75496, Q9H1Z1	Gene names	GMNN
Domain Architecture
Description	Geminin.

RT27_HUMAN
NC score	0.013993 (rank : 67)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	78	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q92552	Gene names	MRPS27, KIAA0264
Domain Architecture	No domain graphic available
Description	Mitochondrial 28S ribosomal protein S27 (S27mt) (MRP-S27).

NALP5_MOUSE
NC score	0.013479 (rank : 68)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	78	Target Neighborhood Hits	560	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

PKHA5_HUMAN
NC score	0.012737 (rank : 69)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	78	Target Neighborhood Hits	455	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

ZN638_HUMAN
NC score	0.011552 (rank : 70)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	78	Target Neighborhood Hits	343	Shared Neighborhood Hits	13
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

PTHR2_MOUSE
NC score	0.011075 (rank : 71)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	78	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q91V95	Gene names	Pthr2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

RMI1_HUMAN
NC score	0.009440 (rank : 72)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	78	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H9A7, Q5SQG8, Q5SQG9, Q6P1Q4, Q6PI89, Q7Z6L6	Gene names	RMI1, C9orf76
Domain Architecture	No domain graphic available
Description	Protein RMI1 homolog.

ZN292_HUMAN
NC score	0.009349 (rank : 73)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	78	Target Neighborhood Hits	918	Shared Neighborhood Hits	14
SwissProt Accessions	O60281, Q9H8G3, Q9H8J4	Gene names	ZNF292, KIAA0530
Domain Architecture	No domain graphic available
Description	Zinc finger protein 292.

MYO3A_HUMAN
NC score	0.009068 (rank : 74)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	78	Target Neighborhood Hits	1033	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

CALX_HUMAN
NC score	0.008516 (rank : 75)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	78	Target Neighborhood Hits	96	Shared Neighborhood Hits	11
SwissProt Accessions	P27824	Gene names	CANX
Domain Architecture
Description	Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90).

SMAD3_HUMAN
NC score	0.007699 (rank : 76)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	78	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	P84022, O09064, O09144, O14510, O35273, Q92940, Q93002, Q9GKR4	Gene names	SMAD3, MADH3
Domain Architecture
Description	Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against DPP homolog 3) (Mad3) (hMAD-3) (JV15-2) (hSMAD3).

SMAD3_MOUSE
NC score	0.007699 (rank : 77)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	78	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BUN5, O09064, O09144, O14510, O35273, Q8BX84, Q92940, Q93002, Q9GKR4	Gene names	Smad3, Madh3
Domain Architecture
Description	Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against DPP homolog 3) (Mad3) (mMad3).

CAD23_MOUSE
NC score	0.006592 (rank : 78)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	78	Target Neighborhood Hits	208	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CAD23_HUMAN
NC score	0.006145 (rank : 79)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	78	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

MIB2_HUMAN
NC score	0.005881 (rank : 80)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	78	Target Neighborhood Hits	438	Shared Neighborhood Hits	5
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).