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Network neighborhood for query Sequence : NRG3_MOUSE

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NRG3_MOUSE
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NRG3_HUMAN
θ value	0 (rank : 1)	NC score	0.984704 (rank : 2)
Query Neighborhood Hits	132	Target Neighborhood Hits	119	Shared Neighborhood Hits	95
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRG3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	132	Target Neighborhood Hits	132	Shared Neighborhood Hits	132
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRG2_MOUSE
θ value	3.28887e-18 (rank : 3)	NC score	0.438927 (rank : 7)
Query Neighborhood Hits	132	Target Neighborhood Hits	392	Shared Neighborhood Hits	64
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NRG1_HUMAN
θ value	3.63628e-17 (rank : 4)	NC score	0.525223 (rank : 4)
Query Neighborhood Hits	132	Target Neighborhood Hits	285	Shared Neighborhood Hits	58
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRG2_HUMAN
θ value	6.41864e-14 (rank : 5)	NC score	0.413051 (rank : 8)
Query Neighborhood Hits	132	Target Neighborhood Hits	419	Shared Neighborhood Hits	59
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

SMDF_HUMAN
θ value	5.08577e-11 (rank : 6)	NC score	0.567292 (rank : 3)
Query Neighborhood Hits	132	Target Neighborhood Hits	117	Shared Neighborhood Hits	56
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

NRG4_HUMAN
θ value	4.92598e-06 (rank : 7)	NC score	0.474820 (rank : 6)
Query Neighborhood Hits	132	Target Neighborhood Hits	85	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_MOUSE
θ value	6.43352e-06 (rank : 8)	NC score	0.493272 (rank : 5)
Query Neighborhood Hits	132	Target Neighborhood Hits	79	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

MUC1_HUMAN
θ value	0.000121331 (rank : 9)	NC score	0.068734 (rank : 103)
Query Neighborhood Hits	132	Target Neighborhood Hits	975	Shared Neighborhood Hits	31
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MDC1_MOUSE
θ value	0.00035302 (rank : 10)	NC score	0.133016 (rank : 22)
Query Neighborhood Hits	132	Target Neighborhood Hits	998	Shared Neighborhood Hits	32
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

BTC_HUMAN
θ value	0.00390308 (rank : 11)	NC score	0.318382 (rank : 9)
Query Neighborhood Hits	132	Target Neighborhood Hits	70	Shared Neighborhood Hits	39
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

EREG_HUMAN
θ value	0.00665767 (rank : 12)	NC score	0.314701 (rank : 10)
Query Neighborhood Hits	132	Target Neighborhood Hits	73	Shared Neighborhood Hits	48
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

BTC_MOUSE
θ value	0.00869519 (rank : 13)	NC score	0.298656 (rank : 11)
Query Neighborhood Hits	132	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

MDC1_HUMAN
θ value	0.0148317 (rank : 14)	NC score	0.095906 (rank : 43)
Query Neighborhood Hits	132	Target Neighborhood Hits	1446	Shared Neighborhood Hits	36
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

EGF_MOUSE
θ value	0.0252991 (rank : 15)	NC score	0.129359 (rank : 24)
Query Neighborhood Hits	132	Target Neighborhood Hits	358	Shared Neighborhood Hits	74
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

EREG_MOUSE
θ value	0.0330416 (rank : 16)	NC score	0.290136 (rank : 12)
Query Neighborhood Hits	132	Target Neighborhood Hits	65	Shared Neighborhood Hits	43
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

MAGE1_HUMAN
θ value	0.0330416 (rank : 17)	NC score	0.062157 (rank : 127)
Query Neighborhood Hits	132	Target Neighborhood Hits	1389	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

TMPS9_MOUSE
θ value	0.0330416 (rank : 18)	NC score	0.027411 (rank : 231)
Query Neighborhood Hits	132	Target Neighborhood Hits	296	Shared Neighborhood Hits	16
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

NACAM_MOUSE
θ value	0.0431538 (rank : 19)	NC score	0.077190 (rank : 71)
Query Neighborhood Hits	132	Target Neighborhood Hits	1866	Shared Neighborhood Hits	46
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

K0240_MOUSE
θ value	0.0736092 (rank : 20)	NC score	0.083073 (rank : 60)
Query Neighborhood Hits	132	Target Neighborhood Hits	211	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

JAG1_HUMAN
θ value	0.125558 (rank : 21)	NC score	0.112709 (rank : 28)
Query Neighborhood Hits	132	Target Neighborhood Hits	514	Shared Neighborhood Hits	71
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

EGF_HUMAN
θ value	0.163984 (rank : 22)	NC score	0.116805 (rank : 25)
Query Neighborhood Hits	132	Target Neighborhood Hits	343	Shared Neighborhood Hits	74
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

JAG1_MOUSE
θ value	0.163984 (rank : 23)	NC score	0.111388 (rank : 29)
Query Neighborhood Hits	132	Target Neighborhood Hits	518	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

NOTC1_MOUSE
θ value	0.163984 (rank : 24)	NC score	0.104554 (rank : 32)
Query Neighborhood Hits	132	Target Neighborhood Hits	916	Shared Neighborhood Hits	80
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

RUNX3_HUMAN
θ value	0.163984 (rank : 25)	NC score	0.054314 (rank : 169)
Query Neighborhood Hits	132	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

TGFA_MOUSE
θ value	0.163984 (rank : 26)	NC score	0.229091 (rank : 13)
Query Neighborhood Hits	132	Target Neighborhood Hits	62	Shared Neighborhood Hits	42
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

DLL4_HUMAN
θ value	0.279714 (rank : 27)	NC score	0.114264 (rank : 26)
Query Neighborhood Hits	132	Target Neighborhood Hits	435	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

BSN_MOUSE
θ value	0.365318 (rank : 28)	NC score	0.052767 (rank : 184)
Query Neighborhood Hits	132	Target Neighborhood Hits	2057	Shared Neighborhood Hits	38
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NOTC4_HUMAN
θ value	0.365318 (rank : 29)	NC score	0.096522 (rank : 41)
Query Neighborhood Hits	132	Target Neighborhood Hits	905	Shared Neighborhood Hits	77
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NTNG2_HUMAN
θ value	0.365318 (rank : 30)	NC score	0.091316 (rank : 50)
Query Neighborhood Hits	132	Target Neighborhood Hits	276	Shared Neighborhood Hits	62
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

TEFF2_HUMAN
θ value	0.365318 (rank : 31)	NC score	0.187001 (rank : 18)
Query Neighborhood Hits	132	Target Neighborhood Hits	211	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	0.365318 (rank : 32)	NC score	0.187258 (rank : 17)
Query Neighborhood Hits	132	Target Neighborhood Hits	214	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TENA_MOUSE
θ value	0.365318 (rank : 33)	NC score	0.073839 (rank : 85)
Query Neighborhood Hits	132	Target Neighborhood Hits	596	Shared Neighborhood Hits	62
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

CD45_HUMAN
θ value	0.47712 (rank : 34)	NC score	0.018703 (rank : 239)
Query Neighborhood Hits	132	Target Neighborhood Hits	243	Shared Neighborhood Hits	17
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

TNR1B_MOUSE
θ value	0.47712 (rank : 35)	NC score	0.032710 (rank : 227)
Query Neighborhood Hits	132	Target Neighborhood Hits	123	Shared Neighborhood Hits	13
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TTLL7_HUMAN
θ value	0.47712 (rank : 36)	NC score	0.034465 (rank : 226)
Query Neighborhood Hits	132	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZT98, Q5TAX8, Q5TAX9, Q6P990, Q86YS1, Q9H5U4	Gene names	TTLL7
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 7 (Protein NYD-SP30).

VASN_MOUSE
θ value	0.47712 (rank : 37)	NC score	0.041515 (rank : 219)
Query Neighborhood Hits	132	Target Neighborhood Hits	426	Shared Neighborhood Hits	53
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ANK2_HUMAN
θ value	0.62314 (rank : 38)	NC score	0.031961 (rank : 228)
Query Neighborhood Hits	132	Target Neighborhood Hits	1615	Shared Neighborhood Hits	37
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CEL_HUMAN
θ value	0.62314 (rank : 39)	NC score	0.026615 (rank : 232)
Query Neighborhood Hits	132	Target Neighborhood Hits	896	Shared Neighborhood Hits	17
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CK024_MOUSE
θ value	0.62314 (rank : 40)	NC score	0.074741 (rank : 81)
Query Neighborhood Hits	132	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CSPG3_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.088850 (rank : 54)
Query Neighborhood Hits	132	Target Neighborhood Hits	676	Shared Neighborhood Hits	74
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	0.62314 (rank : 42)	NC score	0.082328 (rank : 61)
Query Neighborhood Hits	132	Target Neighborhood Hits	657	Shared Neighborhood Hits	75
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

MPDZ_HUMAN
θ value	0.62314 (rank : 43)	NC score	0.020938 (rank : 237)
Query Neighborhood Hits	132	Target Neighborhood Hits	261	Shared Neighborhood Hits	5
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

PDLI7_HUMAN
θ value	0.62314 (rank : 44)	NC score	0.021954 (rank : 235)
Query Neighborhood Hits	132	Target Neighborhood Hits	547	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

AREG_HUMAN
θ value	0.813845 (rank : 45)	NC score	0.208640 (rank : 15)
Query Neighborhood Hits	132	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	P15514	Gene names	AREG
Domain Architecture	No domain graphic available
Description	Amphiregulin precursor (AR) (Colorectum cell-derived growth factor) (CRDGF).

CRUM2_HUMAN
θ value	0.813845 (rank : 46)	NC score	0.102360 (rank : 34)
Query Neighborhood Hits	132	Target Neighborhood Hits	453	Shared Neighborhood Hits	70
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

SLIT3_MOUSE
θ value	0.813845 (rank : 47)	NC score	0.079371 (rank : 68)
Query Neighborhood Hits	132	Target Neighborhood Hits	700	Shared Neighborhood Hits	77
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TSC1_HUMAN
θ value	0.813845 (rank : 48)	NC score	0.024250 (rank : 234)
Query Neighborhood Hits	132	Target Neighborhood Hits	765	Shared Neighborhood Hits	15
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

NTNG2_MOUSE
θ value	1.06291 (rank : 49)	NC score	0.089076 (rank : 53)
Query Neighborhood Hits	132	Target Neighborhood Hits	276	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PGBM_HUMAN
θ value	1.06291 (rank : 50)	NC score	0.063904 (rank : 124)
Query Neighborhood Hits	132	Target Neighborhood Hits	1113	Shared Neighborhood Hits	76
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PRP4B_MOUSE
θ value	1.06291 (rank : 51)	NC score	0.007889 (rank : 250)
Query Neighborhood Hits	132	Target Neighborhood Hits	1040	Shared Neighborhood Hits	10
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

ADA32_MOUSE
θ value	1.38821 (rank : 52)	NC score	0.016825 (rank : 241)
Query Neighborhood Hits	132	Target Neighborhood Hits	219	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ALEX_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.069680 (rank : 98)
Query Neighborhood Hits	132	Target Neighborhood Hits	361	Shared Neighborhood Hits	17
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CSPG2_HUMAN
θ value	1.81305 (rank : 54)	NC score	0.087331 (rank : 56)
Query Neighborhood Hits	132	Target Neighborhood Hits	681	Shared Neighborhood Hits	77
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

MARK2_MOUSE
θ value	1.81305 (rank : 55)	NC score	0.001870 (rank : 256)
Query Neighborhood Hits	132	Target Neighborhood Hits	1018	Shared Neighborhood Hits	15
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

NOTC2_HUMAN
θ value	1.81305 (rank : 56)	NC score	0.101504 (rank : 36)
Query Neighborhood Hits	132	Target Neighborhood Hits	1113	Shared Neighborhood Hits	85
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

AREG_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.172184 (rank : 19)
Query Neighborhood Hits	132	Target Neighborhood Hits	40	Shared Neighborhood Hits	25
SwissProt Accessions	P31955	Gene names	Areg, Sdgf
Domain Architecture	No domain graphic available
Description	Amphiregulin precursor (AR) (Schwannoma-derived growth factor) (SDGF).

DNER_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.113970 (rank : 27)
Query Neighborhood Hits	132	Target Neighborhood Hits	460	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

FATH_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.051418 (rank : 199)
Query Neighborhood Hits	132	Target Neighborhood Hits	570	Shared Neighborhood Hits	69
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FBN1_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.076342 (rank : 76)
Query Neighborhood Hits	132	Target Neighborhood Hits	563	Shared Neighborhood Hits	66
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

KIFC1_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.015600 (rank : 243)
Query Neighborhood Hits	132	Target Neighborhood Hits	545	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

RELN_HUMAN
θ value	2.36792 (rank : 62)	NC score	0.069401 (rank : 99)
Query Neighborhood Hits	132	Target Neighborhood Hits	233	Shared Neighborhood Hits	50
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

CRUM1_MOUSE
θ value	3.0926 (rank : 63)	NC score	0.101248 (rank : 37)
Query Neighborhood Hits	132	Target Neighborhood Hits	444	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

DLL1_MOUSE
θ value	3.0926 (rank : 64)	NC score	0.102739 (rank : 33)
Query Neighborhood Hits	132	Target Neighborhood Hits	456	Shared Neighborhood Hits	67
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

ENTK_MOUSE
θ value	3.0926 (rank : 65)	NC score	0.015223 (rank : 244)
Query Neighborhood Hits	132	Target Neighborhood Hits	338	Shared Neighborhood Hits	17
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

EPGN_MOUSE
θ value	3.0926 (rank : 66)	NC score	0.221267 (rank : 14)
Query Neighborhood Hits	132	Target Neighborhood Hits	63	Shared Neighborhood Hits	48
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

FA12_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.041436 (rank : 220)
Query Neighborhood Hits	132	Target Neighborhood Hits	425	Shared Neighborhood Hits	61
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FBN1_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.075393 (rank : 80)
Query Neighborhood Hits	132	Target Neighborhood Hits	557	Shared Neighborhood Hits	65
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

HNF1A_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.054008 (rank : 173)
Query Neighborhood Hits	132	Target Neighborhood Hits	193	Shared Neighborhood Hits	15
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

NOTC1_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.093484 (rank : 47)
Query Neighborhood Hits	132	Target Neighborhood Hits	906	Shared Neighborhood Hits	78
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PARP4_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.031274 (rank : 229)
Query Neighborhood Hits	132	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

PCQAP_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.049993 (rank : 215)
Query Neighborhood Hits	132	Target Neighborhood Hits	549	Shared Neighborhood Hits	20
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

POGZ_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.006323 (rank : 252)
Query Neighborhood Hits	132	Target Neighborhood Hits	745	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z3K3, O75049, Q8TDZ7, Q9Y4X7	Gene names	POGZ, KIAA0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

RELN_MOUSE
θ value	3.0926 (rank : 74)	NC score	0.068449 (rank : 109)
Query Neighborhood Hits	132	Target Neighborhood Hits	235	Shared Neighborhood Hits	51
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

RHG25_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.012423 (rank : 245)
Query Neighborhood Hits	132	Target Neighborhood Hits	550	Shared Neighborhood Hits	8
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TP53B_MOUSE
θ value	3.0926 (rank : 76)	NC score	0.037202 (rank : 222)
Query Neighborhood Hits	132	Target Neighborhood Hits	644	Shared Neighborhood Hits	28
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

BSN_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.050396 (rank : 209)
Query Neighborhood Hits	132	Target Neighborhood Hits	1537	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CT075_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.016793 (rank : 242)
Query Neighborhood Hits	132	Target Neighborhood Hits	387	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

DLL1_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.102036 (rank : 35)
Query Neighborhood Hits	132	Target Neighborhood Hits	455	Shared Neighborhood Hits	66
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DNER_MOUSE
θ value	4.03905 (rank : 80)	NC score	0.108467 (rank : 31)
Query Neighborhood Hits	132	Target Neighborhood Hits	413	Shared Neighborhood Hits	76
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

GP112_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.036978 (rank : 223)
Query Neighborhood Hits	132	Target Neighborhood Hits	441	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

IER5_MOUSE
θ value	4.03905 (rank : 82)	NC score	0.039082 (rank : 221)
Query Neighborhood Hits	132	Target Neighborhood Hits	110	Shared Neighborhood Hits	9
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

JTB_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.029337 (rank : 230)
Query Neighborhood Hits	132	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	O76095, O95442	Gene names	JTB
Domain Architecture
Description	Protein JTB precursor (Jumping translocation breakpoint protein) (Prostate androgen-regulated protein) (PAR protein).

LRP1B_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.081003 (rank : 64)
Query Neighborhood Hits	132	Target Neighborhood Hits	602	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

RHG12_MOUSE
θ value	4.03905 (rank : 85)	NC score	0.019690 (rank : 238)
Query Neighborhood Hits	132	Target Neighborhood Hits	204	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

SLIT3_HUMAN
θ value	4.03905 (rank : 86)	NC score	0.075589 (rank : 79)
Query Neighborhood Hits	132	Target Neighborhood Hits	682	Shared Neighborhood Hits	76
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

STAB2_MOUSE
θ value	4.03905 (rank : 87)	NC score	0.076714 (rank : 74)
Query Neighborhood Hits	132	Target Neighborhood Hits	528	Shared Neighborhood Hits	66
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

CSPG5_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.068533 (rank : 108)
Query Neighborhood Hits	132	Target Neighborhood Hits	199	Shared Neighborhood Hits	31
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

CSPG5_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.064356 (rank : 120)
Query Neighborhood Hits	132	Target Neighborhood Hits	211	Shared Neighborhood Hits	22
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

DMXL2_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.010593 (rank : 247)
Query Neighborhood Hits	132	Target Neighborhood Hits	374	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

FETUB_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.021073 (rank : 236)
Query Neighborhood Hits	132	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXC1	Gene names	Fetub
Domain Architecture
Description	Fetuin-B precursor (IRL685).

HBEGF_MOUSE
θ value	5.27518 (rank : 92)	NC score	0.158517 (rank : 21)
Query Neighborhood Hits	132	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	Q06186	Gene names	Hbegf, Dtr, Hegfl
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF).

HNF1A_MOUSE
θ value	5.27518 (rank : 93)	NC score	0.052694 (rank : 186)
Query Neighborhood Hits	132	Target Neighborhood Hits	212	Shared Neighborhood Hits	13
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

HSF1_MOUSE
θ value	5.27518 (rank : 94)	NC score	0.017591 (rank : 240)
Query Neighborhood Hits	132	Target Neighborhood Hits	267	Shared Neighborhood Hits	10
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

IPSP_MOUSE
θ value	5.27518 (rank : 95)	NC score	0.003961 (rank : 254)
Query Neighborhood Hits	132	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	P70458	Gene names	Serpina5, Pci
Domain Architecture
Description	Plasma serine protease inhibitor precursor (PCI) (Protein C inhibitor) (Serpin A5) (Plasminogen activator inhibitor 3) (PAI-3) (PAI3).

LAMC1_MOUSE
θ value	5.27518 (rank : 96)	NC score	0.053368 (rank : 177)
Query Neighborhood Hits	132	Target Neighborhood Hits	856	Shared Neighborhood Hits	60
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LRP1_HUMAN
θ value	5.27518 (rank : 97)	NC score	0.079520 (rank : 67)
Query Neighborhood Hits	132	Target Neighborhood Hits	617	Shared Neighborhood Hits	77
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

MFGM_MOUSE
θ value	5.27518 (rank : 98)	NC score	0.073703 (rank : 86)
Query Neighborhood Hits	132	Target Neighborhood Hits	233	Shared Neighborhood Hits	57
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MUC1_MOUSE
θ value	5.27518 (rank : 99)	NC score	0.110737 (rank : 30)
Query Neighborhood Hits	132	Target Neighborhood Hits	388	Shared Neighborhood Hits	28
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC5B_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.081099 (rank : 63)
Query Neighborhood Hits	132	Target Neighborhood Hits	1020	Shared Neighborhood Hits	78
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NDST3_MOUSE
θ value	5.27518 (rank : 101)	NC score	0.007964 (rank : 249)
Query Neighborhood Hits	132	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EQH7, Q6AXE0, Q9D557	Gene names	Ndst3, Hsst3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 3 (EC 2.8.2.-)].

NOTC2_MOUSE
θ value	5.27518 (rank : 102)	NC score	0.097973 (rank : 40)
Query Neighborhood Hits	132	Target Neighborhood Hits	1069	Shared Neighborhood Hits	80
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.093849 (rank : 46)
Query Neighborhood Hits	132	Target Neighborhood Hits	1062	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PRP4B_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.006681 (rank : 251)
Query Neighborhood Hits	132	Target Neighborhood Hits	1030	Shared Neighborhood Hits	10
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

SMC1A_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.004449 (rank : 253)
Query Neighborhood Hits	132	Target Neighborhood Hits	1384	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SYNPO_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.026421 (rank : 233)
Query Neighborhood Hits	132	Target Neighborhood Hits	281	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TENA_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.066754 (rank : 111)
Query Neighborhood Hits	132	Target Neighborhood Hits	631	Shared Neighborhood Hits	63
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TPA_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.036214 (rank : 224)
Query Neighborhood Hits	132	Target Neighborhood Hits	335	Shared Neighborhood Hits	59
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

BAT2_MOUSE
θ value	6.88961 (rank : 109)	NC score	0.047535 (rank : 218)
Query Neighborhood Hits	132	Target Neighborhood Hits	947	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CAC1B_MOUSE
θ value	6.88961 (rank : 110)	NC score	0.011901 (rank : 246)
Query Neighborhood Hits	132	Target Neighborhood Hits	351	Shared Neighborhood Hits	10
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CN155_HUMAN
θ value	6.88961 (rank : 111)	NC score	0.055938 (rank : 149)
Query Neighborhood Hits	132	Target Neighborhood Hits	385	Shared Neighborhood Hits	20
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

FBN2_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.073994 (rank : 83)
Query Neighborhood Hits	132	Target Neighborhood Hits	560	Shared Neighborhood Hits	66
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	6.88961 (rank : 113)	NC score	0.073982 (rank : 84)
Query Neighborhood Hits	132	Target Neighborhood Hits	549	Shared Neighborhood Hits	66
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

HMX3_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.003126 (rank : 255)
Query Neighborhood Hits	132	Target Neighborhood Hits	342	Shared Neighborhood Hits	2
SwissProt Accessions	P42581	Gene names	Hmx3, Nkx-5.1, Nkx5-1
Domain Architecture
Description	Homeobox protein HMX3 (Homeobox protein Nkx-5.1).

JAG2_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.097990 (rank : 39)
Query Neighborhood Hits	132	Target Neighborhood Hits	491	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

LAMA1_MOUSE
θ value	6.88961 (rank : 116)	NC score	0.056238 (rank : 147)
Query Neighborhood Hits	132	Target Neighborhood Hits	838	Shared Neighborhood Hits	60
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA5_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.060347 (rank : 135)
Query Neighborhood Hits	132	Target Neighborhood Hits	828	Shared Neighborhood Hits	61
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB2_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.060326 (rank : 136)
Query Neighborhood Hits	132	Target Neighborhood Hits	692	Shared Neighborhood Hits	59
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.057537 (rank : 144)
Query Neighborhood Hits	132	Target Neighborhood Hits	722	Shared Neighborhood Hits	57
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LEUK_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.053146 (rank : 178)
Query Neighborhood Hits	132	Target Neighborhood Hits	213	Shared Neighborhood Hits	21
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

LRP2_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.069796 (rank : 97)
Query Neighborhood Hits	132	Target Neighborhood Hits	573	Shared Neighborhood Hits	76
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LYAM2_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.049966 (rank : 216)
Query Neighborhood Hits	132	Target Neighborhood Hits	394	Shared Neighborhood Hits	63
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MUC2_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.085874 (rank : 57)
Query Neighborhood Hits	132	Target Neighborhood Hits	906	Shared Neighborhood Hits	75
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PGCA_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.048644 (rank : 217)
Query Neighborhood Hits	132	Target Neighborhood Hits	821	Shared Neighborhood Hits	67
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

STAB1_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.074499 (rank : 82)
Query Neighborhood Hits	132	Target Neighborhood Hits	566	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

TARA_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.035663 (rank : 225)
Query Neighborhood Hits	132	Target Neighborhood Hits	1626	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TGFA_HUMAN
θ value	6.88961 (rank : 127)	NC score	0.167445 (rank : 20)
Query Neighborhood Hits	132	Target Neighborhood Hits	61	Shared Neighborhood Hits	40
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

LAMC1_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.050078 (rank : 213)
Query Neighborhood Hits	132	Target Neighborhood Hits	922	Shared Neighborhood Hits	59
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LRP1B_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.075786 (rank : 78)
Query Neighborhood Hits	132	Target Neighborhood Hits	606	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MEGF6_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.080791 (rank : 65)
Query Neighborhood Hits	132	Target Neighborhood Hits	671	Shared Neighborhood Hits	73
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

NOTC4_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.088836 (rank : 55)
Query Neighborhood Hits	132	Target Neighborhood Hits	872	Shared Neighborhood Hits	77
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

SENP1_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.010359 (rank : 248)
Query Neighborhood Hits	132	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

AGRIN_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.076535 (rank : 75)
Query Neighborhood Hits	132	Target Neighborhood Hits	582	Shared Neighborhood Hits	73
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

C1QR1_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.058331 (rank : 143)
Query Neighborhood Hits	132	Target Neighborhood Hits	493	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.061363 (rank : 131)
Query Neighborhood Hits	132	Target Neighborhood Hits	342	Shared Neighborhood Hits	53
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CD248_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.052051 (rank : 190)
Query Neighborhood Hits	132	Target Neighborhood Hits	578	Shared Neighborhood Hits	59
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CK024_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.064128 (rank : 122)
Query Neighborhood Hits	132	Target Neighborhood Hits	408	Shared Neighborhood Hits	23
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

COMP_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.050863 (rank : 205)
Query Neighborhood Hits	132	Target Neighborhood Hits	290	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CREL1_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.053896 (rank : 174)
Query Neighborhood Hits	132	Target Neighborhood Hits	441	Shared Neighborhood Hits	50
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.052858 (rank : 182)
Query Neighborhood Hits	132	Target Neighborhood Hits	524	Shared Neighborhood Hits	50
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRUM1_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.095263 (rank : 44)
Query Neighborhood Hits	132	Target Neighborhood Hits	457	Shared Neighborhood Hits	73
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CSPG2_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.077025 (rank : 73)
Query Neighborhood Hits	132	Target Neighborhood Hits	711	Shared Neighborhood Hits	75
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CUBN_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.072319 (rank : 88)
Query Neighborhood Hits	132	Target Neighborhood Hits	482	Shared Neighborhood Hits	67
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.071293 (rank : 91)
Query Neighborhood Hits	132	Target Neighborhood Hits	477	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

DLK_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.085415 (rank : 58)
Query Neighborhood Hits	132	Target Neighborhood Hits	401	Shared Neighborhood Hits	61
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.084708 (rank : 59)
Query Neighborhood Hits	132	Target Neighborhood Hits	374	Shared Neighborhood Hits	62
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL3_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.092264 (rank : 49)
Query Neighborhood Hits	132	Target Neighborhood Hits	419	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.093128 (rank : 48)
Query Neighborhood Hits	132	Target Neighborhood Hits	399	Shared Neighborhood Hits	68
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.101167 (rank : 38)
Query Neighborhood Hits	132	Target Neighborhood Hits	440	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

EDIL3_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.073298 (rank : 87)
Query Neighborhood Hits	132	Target Neighborhood Hits	292	Shared Neighborhood Hits	59
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.077385 (rank : 69)
Query Neighborhood Hits	132	Target Neighborhood Hits	317	Shared Neighborhood Hits	63
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.060712 (rank : 134)
Query Neighborhood Hits	132	Target Neighborhood Hits	325	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.064587 (rank : 118)
Query Neighborhood Hits	132	Target Neighborhood Hits	287	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.059451 (rank : 140)
Query Neighborhood Hits	132	Target Neighborhood Hits	270	Shared Neighborhood Hits	49
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.061926 (rank : 128)
Query Neighborhood Hits	132	Target Neighborhood Hits	266	Shared Neighborhood Hits	48
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.093928 (rank : 45)
Query Neighborhood Hits	132	Target Neighborhood Hits	365	Shared Neighborhood Hits	67
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.090898 (rank : 51)
Query Neighborhood Hits	132	Target Neighborhood Hits	379	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EPGN_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.197392 (rank : 16)
Query Neighborhood Hits	132	Target Neighborhood Hits	59	Shared Neighborhood Hits	43
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

FBLN1_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.054510 (rank : 165)
Query Neighborhood Hits	132	Target Neighborhood Hits	324	Shared Neighborhood Hits	45
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.054555 (rank : 163)
Query Neighborhood Hits	132	Target Neighborhood Hits	329	Shared Neighborhood Hits	48
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.059204 (rank : 141)
Query Neighborhood Hits	132	Target Neighborhood Hits	392	Shared Neighborhood Hits	52
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.060282 (rank : 137)
Query Neighborhood Hits	132	Target Neighborhood Hits	505	Shared Neighborhood Hits	62
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.051747 (rank : 192)
Query Neighborhood Hits	132	Target Neighborhood Hits	293	Shared Neighborhood Hits	46
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.051978 (rank : 191)
Query Neighborhood Hits	132	Target Neighborhood Hits	279	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.053087 (rank : 179)
Query Neighborhood Hits	132	Target Neighborhood Hits	278	Shared Neighborhood Hits	45
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.051547 (rank : 194)
Query Neighborhood Hits	132	Target Neighborhood Hits	270	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.054172 (rank : 170)
Query Neighborhood Hits	132	Target Neighborhood Hits	329	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.053586 (rank : 176)
Query Neighborhood Hits	132	Target Neighborhood Hits	317	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN3_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.069984 (rank : 95)
Query Neighborhood Hits	132	Target Neighborhood Hits	543	Shared Neighborhood Hits	63
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

GAS6_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.055107 (rank : 154)
Query Neighborhood Hits	132	Target Neighborhood Hits	348	Shared Neighborhood Hits	51
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.055709 (rank : 150)
Query Neighborhood Hits	132	Target Neighborhood Hits	343	Shared Neighborhood Hits	52
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GSCR1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.059952 (rank : 139)
Query Neighborhood Hits	132	Target Neighborhood Hits	674	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HBEGF_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.131534 (rank : 23)
Query Neighborhood Hits	132	Target Neighborhood Hits	61	Shared Neighborhood Hits	37
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

HHIP_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.056096 (rank : 148)
Query Neighborhood Hits	132	Target Neighborhood Hits	249	Shared Neighborhood Hits	51
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.055411 (rank : 153)
Query Neighborhood Hits	132	Target Neighborhood Hits	219	Shared Neighborhood Hits	50
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

JAG2_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.096197 (rank : 42)
Query Neighborhood Hits	132	Target Neighborhood Hits	504	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KR104_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.052566 (rank : 187)
Query Neighborhood Hits	132	Target Neighborhood Hits	313	Shared Neighborhood Hits	42
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR106_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.051431 (rank : 198)
Query Neighborhood Hits	132	Target Neighborhood Hits	347	Shared Neighborhood Hits	43
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.054508 (rank : 167)
Query Neighborhood Hits	132	Target Neighborhood Hits	330	Shared Neighborhood Hits	43
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KRA51_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.063184 (rank : 125)
Query Neighborhood Hits	132	Target Neighborhood Hits	288	Shared Neighborhood Hits	45
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA53_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.054152 (rank : 172)
Query Neighborhood Hits	132	Target Neighborhood Hits	331	Shared Neighborhood Hits	43
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA58_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.050568 (rank : 206)
Query Neighborhood Hits	132	Target Neighborhood Hits	324	Shared Neighborhood Hits	42
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LAMA1_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.053630 (rank : 175)
Query Neighborhood Hits	132	Target Neighborhood Hits	804	Shared Neighborhood Hits	55
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA5_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.054992 (rank : 157)
Query Neighborhood Hits	132	Target Neighborhood Hits	976	Shared Neighborhood Hits	60
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB1_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.050873 (rank : 204)
Query Neighborhood Hits	132	Target Neighborhood Hits	919	Shared Neighborhood Hits	52
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.050105 (rank : 212)
Query Neighborhood Hits	132	Target Neighborhood Hits	444	Shared Neighborhood Hits	54
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC2_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.050411 (rank : 208)
Query Neighborhood Hits	132	Target Neighborhood Hits	715	Shared Neighborhood Hits	58
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC2_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.052101 (rank : 189)
Query Neighborhood Hits	132	Target Neighborhood Hits	614	Shared Neighborhood Hits	60
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.052774 (rank : 183)
Query Neighborhood Hits	132	Target Neighborhood Hits	588	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.053084 (rank : 180)
Query Neighborhood Hits	132	Target Neighborhood Hits	624	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LDLR_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.051353 (rank : 202)
Query Neighborhood Hits	132	Target Neighborhood Hits	375	Shared Neighborhood Hits	45
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.051374 (rank : 201)
Query Neighborhood Hits	132	Target Neighborhood Hits	382	Shared Neighborhood Hits	48
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP8_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.050043 (rank : 214)
Query Neighborhood Hits	132	Target Neighborhood Hits	385	Shared Neighborhood Hits	45
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTB1L_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.061643 (rank : 129)
Query Neighborhood Hits	132	Target Neighborhood Hits	553	Shared Neighborhood Hits	64
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.065162 (rank : 114)
Query Neighborhood Hits	132	Target Neighborhood Hits	514	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.065036 (rank : 115)
Query Neighborhood Hits	132	Target Neighborhood Hits	502	Shared Neighborhood Hits	66
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.065002 (rank : 117)
Query Neighborhood Hits	132	Target Neighborhood Hits	479	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.065456 (rank : 113)
Query Neighborhood Hits	132	Target Neighborhood Hits	552	Shared Neighborhood Hits	68
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.064575 (rank : 119)
Query Neighborhood Hits	132	Target Neighborhood Hits	617	Shared Neighborhood Hits	64
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.064272 (rank : 121)
Query Neighborhood Hits	132	Target Neighborhood Hits	502	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.064108 (rank : 123)
Query Neighborhood Hits	132	Target Neighborhood Hits	475	Shared Neighborhood Hits	61
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.067399 (rank : 110)
Query Neighborhood Hits	132	Target Neighborhood Hits	607	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MEGF8_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.053056 (rank : 181)
Query Neighborhood Hits	132	Target Neighborhood Hits	528	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.052706 (rank : 185)
Query Neighborhood Hits	132	Target Neighborhood Hits	520	Shared Neighborhood Hits	53
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.068573 (rank : 105)
Query Neighborhood Hits	132	Target Neighborhood Hits	557	Shared Neighborhood Hits	70
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.066606 (rank : 112)
Query Neighborhood Hits	132	Target Neighborhood Hits	896	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MUC13_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.070484 (rank : 94)
Query Neighborhood Hits	132	Target Neighborhood Hits	447	Shared Neighborhood Hits	56
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC7_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.072093 (rank : 89)
Query Neighborhood Hits	132	Target Neighborhood Hits	538	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NAGPA_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.060235 (rank : 138)
Query Neighborhood Hits	132	Target Neighborhood Hits	282	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NAGPA_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.060769 (rank : 133)
Query Neighborhood Hits	132	Target Neighborhood Hits	308	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NELL1_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.069241 (rank : 100)
Query Neighborhood Hits	132	Target Neighborhood Hits	451	Shared Neighborhood Hits	62
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.070746 (rank : 93)
Query Neighborhood Hits	132	Target Neighborhood Hits	449	Shared Neighborhood Hits	64
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.068752 (rank : 102)
Query Neighborhood Hits	132	Target Neighborhood Hits	436	Shared Neighborhood Hits	62
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NID1_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.054153 (rank : 171)
Query Neighborhood Hits	132	Target Neighborhood Hits	329	Shared Neighborhood Hits	48
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.055040 (rank : 156)
Query Neighborhood Hits	132	Target Neighborhood Hits	335	Shared Neighborhood Hits	52
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.054627 (rank : 159)
Query Neighborhood Hits	132	Target Neighborhood Hits	456	Shared Neighborhood Hits	57
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.056407 (rank : 146)
Query Neighborhood Hits	132	Target Neighborhood Hits	338	Shared Neighborhood Hits	50
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOTC3_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.090587 (rank : 52)
Query Neighborhood Hits	132	Target Neighborhood Hits	975	Shared Neighborhood Hits	84
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NTNG1_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.063068 (rank : 126)
Query Neighborhood Hits	132	Target Neighborhood Hits	247	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.061467 (rank : 130)
Query Neighborhood Hits	132	Target Neighborhood Hits	246	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NU214_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.050565 (rank : 207)
Query Neighborhood Hits	132	Target Neighborhood Hits	657	Shared Neighborhood Hits	27
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PGBM_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.054565 (rank : 162)
Query Neighborhood Hits	132	Target Neighborhood Hits	1073	Shared Neighborhood Hits	72
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PO121_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.052237 (rank : 188)
Query Neighborhood Hits	132	Target Neighborhood Hits	344	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PO121_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.050339 (rank : 210)
Query Neighborhood Hits	132	Target Neighborhood Hits	345	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PRG4_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.065023 (rank : 116)
Query Neighborhood Hits	132	Target Neighborhood Hits	764	Shared Neighborhood Hits	37
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PROS_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.054424 (rank : 168)
Query Neighborhood Hits	132	Target Neighborhood Hits	340	Shared Neighborhood Hits	50
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.054509 (rank : 166)
Query Neighborhood Hits	132	Target Neighborhood Hits	330	Shared Neighborhood Hits	50
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SCUB3_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.054610 (rank : 161)
Query Neighborhood Hits	132	Target Neighborhood Hits	428	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.054622 (rank : 160)
Query Neighborhood Hits	132	Target Neighborhood Hits	442	Shared Neighborhood Hits	50
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SLIT1_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.068723 (rank : 104)
Query Neighborhood Hits	132	Target Neighborhood Hits	700	Shared Neighborhood Hits	73
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT1_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.071091 (rank : 92)
Query Neighborhood Hits	132	Target Neighborhood Hits	715	Shared Neighborhood Hits	72
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT2_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.069933 (rank : 96)
Query Neighborhood Hits	132	Target Neighborhood Hits	708	Shared Neighborhood Hits	72
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.069023 (rank : 101)
Query Neighborhood Hits	132	Target Neighborhood Hits	684	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SREC2_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.077026 (rank : 72)
Query Neighborhood Hits	132	Target Neighborhood Hits	645	Shared Neighborhood Hits	71
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.077351 (rank : 70)
Query Neighborhood Hits	132	Target Neighborhood Hits	605	Shared Neighborhood Hits	72
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.071534 (rank : 90)
Query Neighborhood Hits	132	Target Neighborhood Hits	645	Shared Neighborhood Hits	68
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

SRRM1_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.051467 (rank : 196)
Query Neighborhood Hits	132	Target Neighborhood Hits	690	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

STAB1_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.068558 (rank : 106)
Query Neighborhood Hits	132	Target Neighborhood Hits	546	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB2_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.068544 (rank : 107)
Query Neighborhood Hits	132	Target Neighborhood Hits	534	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

SUSD1_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.056792 (rank : 145)
Query Neighborhood Hits	132	Target Neighborhood Hits	285	Shared Neighborhood Hits	46
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TDGF1_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.050327 (rank : 211)
Query Neighborhood Hits	132	Target Neighborhood Hits	132	Shared Neighborhood Hits	43
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF1_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.055066 (rank : 155)
Query Neighborhood Hits	132	Target Neighborhood Hits	146	Shared Neighborhood Hits	48
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.051746 (rank : 193)
Query Neighborhood Hits	132	Target Neighborhood Hits	131	Shared Neighborhood Hits	43
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TENX_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.060800 (rank : 132)
Query Neighborhood Hits	132	Target Neighborhood Hits	789	Shared Neighborhood Hits	61
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TRBM_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.055474 (rank : 151)
Query Neighborhood Hits	132	Target Neighborhood Hits	339	Shared Neighborhood Hits	46
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.054882 (rank : 158)
Query Neighborhood Hits	132	Target Neighborhood Hits	361	Shared Neighborhood Hits	49
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSP4_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.051439 (rank : 197)
Query Neighborhood Hits	132	Target Neighborhood Hits	277	Shared Neighborhood Hits	49
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.051395 (rank : 200)
Query Neighborhood Hits	132	Target Neighborhood Hits	276	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROM_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.054534 (rank : 164)
Query Neighborhood Hits	132	Target Neighborhood Hits	284	Shared Neighborhood Hits	50
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.055420 (rank : 152)
Query Neighborhood Hits	132	Target Neighborhood Hits	276	Shared Neighborhood Hits	50
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

VLDLR_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.051474 (rank : 195)
Query Neighborhood Hits	132	Target Neighborhood Hits	383	Shared Neighborhood Hits	48
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.050944 (rank : 203)
Query Neighborhood Hits	132	Target Neighborhood Hits	360	Shared Neighborhood Hits	47
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

WIF1_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.079862 (rank : 66)
Query Neighborhood Hits	132	Target Neighborhood Hits	392	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.081425 (rank : 62)
Query Neighborhood Hits	132	Target Neighborhood Hits	393	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ZAN_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.058856 (rank : 142)
Query Neighborhood Hits	132	Target Neighborhood Hits	679	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZAN_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.076296 (rank : 77)
Query Neighborhood Hits	132	Target Neighborhood Hits	808	Shared Neighborhood Hits	80
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

NRG3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	132	Target Neighborhood Hits	132	Shared Neighborhood Hits	132
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRG3_HUMAN
NC score	0.984704 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	132	Target Neighborhood Hits	119	Shared Neighborhood Hits	95
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

SMDF_HUMAN
NC score	0.567292 (rank : 3)	θ value	5.08577e-11 (rank : 6)
Query Neighborhood Hits	132	Target Neighborhood Hits	117	Shared Neighborhood Hits	56
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

NRG1_HUMAN
NC score	0.525223 (rank : 4)	θ value	3.63628e-17 (rank : 4)
Query Neighborhood Hits	132	Target Neighborhood Hits	285	Shared Neighborhood Hits	58
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRG4_MOUSE
NC score	0.493272 (rank : 5)	θ value	6.43352e-06 (rank : 8)
Query Neighborhood Hits	132	Target Neighborhood Hits	79	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_HUMAN
NC score	0.474820 (rank : 6)	θ value	4.92598e-06 (rank : 7)
Query Neighborhood Hits	132	Target Neighborhood Hits	85	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG2_MOUSE
NC score	0.438927 (rank : 7)	θ value	3.28887e-18 (rank : 3)
Query Neighborhood Hits	132	Target Neighborhood Hits	392	Shared Neighborhood Hits	64
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NRG2_HUMAN
NC score	0.413051 (rank : 8)	θ value	6.41864e-14 (rank : 5)
Query Neighborhood Hits	132	Target Neighborhood Hits	419	Shared Neighborhood Hits	59
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

BTC_HUMAN
NC score	0.318382 (rank : 9)	θ value	0.00390308 (rank : 11)
Query Neighborhood Hits	132	Target Neighborhood Hits	70	Shared Neighborhood Hits	39
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

EREG_HUMAN
NC score	0.314701 (rank : 10)	θ value	0.00665767 (rank : 12)
Query Neighborhood Hits	132	Target Neighborhood Hits	73	Shared Neighborhood Hits	48
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

BTC_MOUSE
NC score	0.298656 (rank : 11)	θ value	0.00869519 (rank : 13)
Query Neighborhood Hits	132	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

EREG_MOUSE
NC score	0.290136 (rank : 12)	θ value	0.0330416 (rank : 16)
Query Neighborhood Hits	132	Target Neighborhood Hits	65	Shared Neighborhood Hits	43
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

TGFA_MOUSE
NC score	0.229091 (rank : 13)	θ value	0.163984 (rank : 26)
Query Neighborhood Hits	132	Target Neighborhood Hits	62	Shared Neighborhood Hits	42
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

EPGN_MOUSE
NC score	0.221267 (rank : 14)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	132	Target Neighborhood Hits	63	Shared Neighborhood Hits	48
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

AREG_HUMAN
NC score	0.208640 (rank : 15)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	132	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	P15514	Gene names	AREG
Domain Architecture	No domain graphic available
Description	Amphiregulin precursor (AR) (Colorectum cell-derived growth factor) (CRDGF).

EPGN_HUMAN
NC score	0.197392 (rank : 16)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	132	Target Neighborhood Hits	59	Shared Neighborhood Hits	43
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

TEFF2_MOUSE
NC score	0.187258 (rank : 17)	θ value	0.365318 (rank : 32)
Query Neighborhood Hits	132	Target Neighborhood Hits	214	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TEFF2_HUMAN
NC score	0.187001 (rank : 18)	θ value	0.365318 (rank : 31)
Query Neighborhood Hits	132	Target Neighborhood Hits	211	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

AREG_MOUSE
NC score	0.172184 (rank : 19)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	132	Target Neighborhood Hits	40	Shared Neighborhood Hits	25
SwissProt Accessions	P31955	Gene names	Areg, Sdgf
Domain Architecture	No domain graphic available
Description	Amphiregulin precursor (AR) (Schwannoma-derived growth factor) (SDGF).

TGFA_HUMAN
NC score	0.167445 (rank : 20)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	132	Target Neighborhood Hits	61	Shared Neighborhood Hits	40
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

HBEGF_MOUSE
NC score	0.158517 (rank : 21)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	132	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	Q06186	Gene names	Hbegf, Dtr, Hegfl
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF).

MDC1_MOUSE
NC score	0.133016 (rank : 22)	θ value	0.00035302 (rank : 10)
Query Neighborhood Hits	132	Target Neighborhood Hits	998	Shared Neighborhood Hits	32
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

HBEGF_HUMAN
NC score	0.131534 (rank : 23)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	132	Target Neighborhood Hits	61	Shared Neighborhood Hits	37
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

EGF_MOUSE
NC score	0.129359 (rank : 24)	θ value	0.0252991 (rank : 15)
Query Neighborhood Hits	132	Target Neighborhood Hits	358	Shared Neighborhood Hits	74
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

EGF_HUMAN
NC score	0.116805 (rank : 25)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	132	Target Neighborhood Hits	343	Shared Neighborhood Hits	74
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

DLL4_HUMAN
NC score	0.114264 (rank : 26)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	132	Target Neighborhood Hits	435	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
NC score	0.113970 (rank : 27)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	132	Target Neighborhood Hits	460	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

JAG1_HUMAN
NC score	0.112709 (rank : 28)	θ value	0.125558 (rank : 21)
Query Neighborhood Hits	132	Target Neighborhood Hits	514	Shared Neighborhood Hits	71
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
NC score	0.111388 (rank : 29)	θ value	0.163984 (rank : 23)
Query Neighborhood Hits	132	Target Neighborhood Hits	518	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

MUC1_MOUSE
NC score	0.110737 (rank : 30)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	132	Target Neighborhood Hits	388	Shared Neighborhood Hits	28
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

DNER_MOUSE
NC score	0.108467 (rank : 31)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	132	Target Neighborhood Hits	413	Shared Neighborhood Hits	76
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

NOTC1_MOUSE
NC score	0.104554 (rank : 32)	θ value	0.163984 (rank : 24)
Query Neighborhood Hits	132	Target Neighborhood Hits	916	Shared Neighborhood Hits	80
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DLL1_MOUSE
NC score	0.102739 (rank : 33)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	132	Target Neighborhood Hits	456	Shared Neighborhood Hits	67
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

CRUM2_HUMAN
NC score	0.102360 (rank : 34)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	132	Target Neighborhood Hits	453	Shared Neighborhood Hits	70
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

DLL1_HUMAN
NC score	0.102036 (rank : 35)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	132	Target Neighborhood Hits	455	Shared Neighborhood Hits	66
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

NOTC2_HUMAN
NC score	0.101504 (rank : 36)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	132	Target Neighborhood Hits	1113	Shared Neighborhood Hits	85
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CRUM1_MOUSE
NC score	0.101248 (rank : 37)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	132	Target Neighborhood Hits	444	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

DLL4_MOUSE
NC score	0.101167 (rank : 38)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	132	Target Neighborhood Hits	440	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

JAG2_HUMAN
NC score	0.097990 (rank : 39)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	132	Target Neighborhood Hits	491	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

NOTC2_MOUSE
NC score	0.097973 (rank : 40)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	132	Target Neighborhood Hits	1069	Shared Neighborhood Hits	80
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC4_HUMAN
NC score	0.096522 (rank : 41)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	132	Target Neighborhood Hits	905	Shared Neighborhood Hits	77
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

JAG2_MOUSE
NC score	0.096197 (rank : 42)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	132	Target Neighborhood Hits	504	Shared Neighborhood Hits	70
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

MDC1_HUMAN
NC score	0.095906 (rank : 43)	θ value	0.0148317 (rank : 14)
Query Neighborhood Hits	132	Target Neighborhood Hits	1446	Shared Neighborhood Hits	36
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CRUM1_HUMAN
NC score	0.095263 (rank : 44)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	132	Target Neighborhood Hits	457	Shared Neighborhood Hits	73
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

EGFL9_HUMAN
NC score	0.093928 (rank : 45)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	132	Target Neighborhood Hits	365	Shared Neighborhood Hits	67
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

NOTC3_HUMAN
NC score	0.093849 (rank : 46)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	132	Target Neighborhood Hits	1062	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC1_HUMAN
NC score	0.093484 (rank : 47)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	132	Target Neighborhood Hits	906	Shared Neighborhood Hits	78
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DLL3_MOUSE
NC score	0.093128 (rank : 48)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	132	Target Neighborhood Hits	399	Shared Neighborhood Hits	68
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL3_HUMAN
NC score	0.092264 (rank : 49)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	132	Target Neighborhood Hits	419	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

NTNG2_HUMAN
NC score	0.091316 (rank : 50)	θ value	0.365318 (rank : 30)
Query Neighborhood Hits	132	Target Neighborhood Hits	276	Shared Neighborhood Hits	62
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

EGFL9_MOUSE
NC score	0.090898 (rank : 51)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	132	Target Neighborhood Hits	379	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

NOTC3_MOUSE
NC score	0.090587 (rank : 52)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	132	Target Neighborhood Hits	975	Shared Neighborhood Hits	84
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NTNG2_MOUSE
NC score	0.089076 (rank : 53)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	132	Target Neighborhood Hits	276	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

CSPG3_HUMAN
NC score	0.088850 (rank : 54)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	132	Target Neighborhood Hits	676	Shared Neighborhood Hits	74
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

NOTC4_MOUSE
NC score	0.088836 (rank : 55)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	132	Target Neighborhood Hits	872	Shared Neighborhood Hits	77
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

CSPG2_HUMAN
NC score	0.087331 (rank : 56)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	132	Target Neighborhood Hits	681	Shared Neighborhood Hits	77
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

MUC2_HUMAN
NC score	0.085874 (rank : 57)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	132	Target Neighborhood Hits	906	Shared Neighborhood Hits	75
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

DLK_HUMAN
NC score	0.085415 (rank : 58)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	132	Target Neighborhood Hits	401	Shared Neighborhood Hits	61
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
NC score	0.084708 (rank : 59)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	132	Target Neighborhood Hits	374	Shared Neighborhood Hits	62
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

K0240_MOUSE
NC score	0.083073 (rank : 60)	θ value	0.0736092 (rank : 20)
Query Neighborhood Hits	132	Target Neighborhood Hits	211	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

CSPG3_MOUSE
NC score	0.082328 (rank : 61)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	132	Target Neighborhood Hits	657	Shared Neighborhood Hits	75
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

WIF1_MOUSE
NC score	0.081425 (rank : 62)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	132	Target Neighborhood Hits	393	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

MUC5B_HUMAN
NC score	0.081099 (rank : 63)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	132	Target Neighborhood Hits	1020	Shared Neighborhood Hits	78
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

LRP1B_HUMAN
NC score	0.081003 (rank : 64)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	132	Target Neighborhood Hits	602	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MEGF6_HUMAN
NC score	0.080791 (rank : 65)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	132	Target Neighborhood Hits	671	Shared Neighborhood Hits	73
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

WIF1_HUMAN
NC score	0.079862 (rank : 66)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	132	Target Neighborhood Hits	392	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

LRP1_HUMAN
NC score	0.079520 (rank : 67)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	132	Target Neighborhood Hits	617	Shared Neighborhood Hits	77
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

SLIT3_MOUSE
NC score	0.079371 (rank : 68)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	132	Target Neighborhood Hits	700	Shared Neighborhood Hits	77
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

EDIL3_MOUSE
NC score	0.077385 (rank : 69)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	132	Target Neighborhood Hits	317	Shared Neighborhood Hits	63
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

SREC2_MOUSE
NC score	0.077351 (rank : 70)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	132	Target Neighborhood Hits	605	Shared Neighborhood Hits	72
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

NACAM_MOUSE
NC score	0.077190 (rank : 71)	θ value	0.0431538 (rank : 19)
Query Neighborhood Hits	132	Target Neighborhood Hits	1866	Shared Neighborhood Hits	46
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SREC2_HUMAN
NC score	0.077026 (rank : 72)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	132	Target Neighborhood Hits	645	Shared Neighborhood Hits	71
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

CSPG2_MOUSE
NC score	0.077025 (rank : 73)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	132	Target Neighborhood Hits	711	Shared Neighborhood Hits	75
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

STAB2_MOUSE
NC score	0.076714 (rank : 74)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	132	Target Neighborhood Hits	528	Shared Neighborhood Hits	66
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

AGRIN_HUMAN
NC score	0.076535 (rank : 75)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	132	Target Neighborhood Hits	582	Shared Neighborhood Hits	73
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

FBN1_MOUSE
NC score	0.076342 (rank : 76)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	132	Target Neighborhood Hits	563	Shared Neighborhood Hits	66
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

ZAN_MOUSE
NC score	0.076296 (rank : 77)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	132	Target Neighborhood Hits	808	Shared Neighborhood Hits	80
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

LRP1B_MOUSE
NC score	0.075786 (rank : 78)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	132	Target Neighborhood Hits	606	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

SLIT3_HUMAN
NC score	0.075589 (rank : 79)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	132	Target Neighborhood Hits	682	Shared Neighborhood Hits	76
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

FBN1_HUMAN
NC score	0.075393 (rank : 80)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	132	Target Neighborhood Hits	557	Shared Neighborhood Hits	65
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

CK024_MOUSE
NC score	0.074741 (rank : 81)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	132	Target Neighborhood Hits	307	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

STAB1_MOUSE
NC score	0.074499 (rank : 82)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	132	Target Neighborhood Hits	566	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

FBN2_HUMAN
NC score	0.073994 (rank : 83)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	132	Target Neighborhood Hits	560	Shared Neighborhood Hits	66
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
NC score	0.073982 (rank : 84)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	132	Target Neighborhood Hits	549	Shared Neighborhood Hits	66
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

TENA_MOUSE
NC score	0.073839 (rank : 85)	θ value	0.365318 (rank : 33)
Query Neighborhood Hits	132	Target Neighborhood Hits	596	Shared Neighborhood Hits	62
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

MFGM_MOUSE
NC score	0.073703 (rank : 86)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	132	Target Neighborhood Hits	233	Shared Neighborhood Hits	57
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

EDIL3_HUMAN
NC score	0.073298 (rank : 87)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	132	Target Neighborhood Hits	292	Shared Neighborhood Hits	59
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

CUBN_HUMAN
NC score	0.072319 (rank : 88)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	132	Target Neighborhood Hits	482	Shared Neighborhood Hits	67
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

MUC7_HUMAN
NC score	0.072093 (rank : 89)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	132	Target Neighborhood Hits	538	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

SREC_HUMAN
NC score	0.071534 (rank : 90)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	132	Target Neighborhood Hits	645	Shared Neighborhood Hits	68
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

CUBN_MOUSE
NC score	0.071293 (rank : 91)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	132	Target Neighborhood Hits	477	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

SLIT1_MOUSE
NC score	0.071091 (rank : 92)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	132	Target Neighborhood Hits	715	Shared Neighborhood Hits	72
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

NELL2_HUMAN
NC score	0.070746 (rank : 93)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	132	Target Neighborhood Hits	449	Shared Neighborhood Hits	64
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

MUC13_MOUSE
NC score	0.070484 (rank : 94)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	132	Target Neighborhood Hits	447	Shared Neighborhood Hits	56
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

FBN3_HUMAN
NC score	0.069984 (rank : 95)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	132	Target Neighborhood Hits	543	Shared Neighborhood Hits	63
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

SLIT2_HUMAN
NC score	0.069933 (rank : 96)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	132	Target Neighborhood Hits	708	Shared Neighborhood Hits	72
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

LRP2_HUMAN
NC score	0.069796 (rank : 97)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	132	Target Neighborhood Hits	573	Shared Neighborhood Hits	76
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

ALEX_HUMAN
NC score	0.069680 (rank : 98)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	132	Target Neighborhood Hits	361	Shared Neighborhood Hits	17
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

RELN_HUMAN
NC score	0.069401 (rank : 99)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	132	Target Neighborhood Hits	233	Shared Neighborhood Hits	50
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

NELL1_HUMAN
NC score	0.069241 (rank : 100)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	132	Target Neighborhood Hits	451	Shared Neighborhood Hits	62
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

SLIT2_MOUSE
NC score	0.069023 (rank : 101)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	132	Target Neighborhood Hits	684	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

NELL2_MOUSE
NC score	0.068752 (rank : 102)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	132	Target Neighborhood Hits	436	Shared Neighborhood Hits	62
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

MUC1_HUMAN
NC score	0.068734 (rank : 103)	θ value	0.000121331 (rank : 9)
Query Neighborhood Hits	132	Target Neighborhood Hits	975	Shared Neighborhood Hits	31
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SLIT1_HUMAN
NC score	0.068723 (rank : 104)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	132	Target Neighborhood Hits	700	Shared Neighborhood Hits	73
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

MEGF9_HUMAN
NC score	0.068573 (rank : 105)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	132	Target Neighborhood Hits	557	Shared Neighborhood Hits	70
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

STAB1_HUMAN
NC score	0.068558 (rank : 106)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	132	Target Neighborhood Hits	546	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB2_HUMAN
NC score	0.068544 (rank : 107)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	132	Target Neighborhood Hits	534	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

CSPG5_HUMAN
NC score	0.068533 (rank : 108)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	132	Target Neighborhood Hits	199	Shared Neighborhood Hits	31
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

RELN_MOUSE
NC score	0.068449 (rank : 109)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	132	Target Neighborhood Hits	235	Shared Neighborhood Hits	51
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

LTBP4_MOUSE
NC score	0.067399 (rank : 110)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	132	Target Neighborhood Hits	607	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

TENA_HUMAN
NC score	0.066754 (rank : 111)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	132	Target Neighborhood Hits	631	Shared Neighborhood Hits	63
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

MEGF9_MOUSE
NC score	0.066606 (rank : 112)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	132	Target Neighborhood Hits	896	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LTBP2_HUMAN
NC score	0.065456 (rank : 113)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	132	Target Neighborhood Hits	552	Shared Neighborhood Hits	68
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTB1L_MOUSE
NC score	0.065162 (rank : 114)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	132	Target Neighborhood Hits	514	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.065036 (rank : 115)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	132	Target Neighborhood Hits	502	Shared Neighborhood Hits	66
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

PRG4_HUMAN
NC score	0.065023 (rank : 116)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	132	Target Neighborhood Hits	764	Shared Neighborhood Hits	37
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

LTB1S_MOUSE
NC score	0.065002 (rank : 117)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	132	Target Neighborhood Hits	479	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

EGFL7_MOUSE
NC score	0.064587 (rank : 118)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	132	Target Neighborhood Hits	287	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

LTBP2_MOUSE
NC score	0.064575 (rank : 119)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	132	Target Neighborhood Hits	617	Shared Neighborhood Hits	64
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

CSPG5_MOUSE
NC score	0.064356 (rank : 120)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	132	Target Neighborhood Hits	211	Shared Neighborhood Hits	22
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

LTBP3_HUMAN
NC score	0.064272 (rank : 121)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	132	Target Neighborhood Hits	502	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

CK024_HUMAN
NC score	0.064128 (rank : 122)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	132	Target Neighborhood Hits	408	Shared Neighborhood Hits	23
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

LTBP3_MOUSE
NC score	0.064108 (rank : 123)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	132	Target Neighborhood Hits	475	Shared Neighborhood Hits	61
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

PGBM_HUMAN
NC score	0.063904 (rank : 124)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	132	Target Neighborhood Hits	1113	Shared Neighborhood Hits	76
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

KRA51_HUMAN
NC score	0.063184 (rank : 125)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	132	Target Neighborhood Hits	288	Shared Neighborhood Hits	45
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

NTNG1_HUMAN
NC score	0.063068 (rank : 126)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	132	Target Neighborhood Hits	247	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

MAGE1_HUMAN
NC score	0.062157 (rank : 127)	θ value	0.0330416 (rank : 17)
Query Neighborhood Hits	132	Target Neighborhood Hits	1389	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

EGFL8_MOUSE
NC score	0.061926 (rank : 128)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	132	Target Neighborhood Hits	266	Shared Neighborhood Hits	48
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

LTB1L_HUMAN
NC score	0.061643 (rank : 129)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	132	Target Neighborhood Hits	553	Shared Neighborhood Hits	64
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NTNG1_MOUSE
NC score	0.061467 (rank : 130)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	132	Target Neighborhood Hits	246	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

C1QR1_MOUSE
NC score	0.061363 (rank : 131)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	132	Target Neighborhood Hits	342	Shared Neighborhood Hits	53
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

TENX_HUMAN
NC score	0.060800 (rank : 132)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	132	Target Neighborhood Hits	789	Shared Neighborhood Hits	61
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

NAGPA_MOUSE
NC score	0.060769 (rank : 133)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	132	Target Neighborhood Hits	308	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

EGFL7_HUMAN
NC score	0.060712 (rank : 134)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	132	Target Neighborhood Hits	325	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

LAMA5_MOUSE
NC score	0.060347 (rank : 135)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	132	Target Neighborhood Hits	828	Shared Neighborhood Hits	61
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB2_HUMAN
NC score	0.060326 (rank : 136)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	132	Target Neighborhood Hits	692	Shared Neighborhood Hits	59
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

FBLN2_MOUSE
NC score	0.060282 (rank : 137)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	132	Target Neighborhood Hits	505	Shared Neighborhood Hits	62
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

NAGPA_HUMAN
NC score	0.060235 (rank : 138)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	132	Target Neighborhood Hits	282	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

GSCR1_HUMAN
NC score	0.059952 (rank : 139)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	132	Target Neighborhood Hits	674	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

EGFL8_HUMAN
NC score	0.059451 (rank : 140)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	132	Target Neighborhood Hits	270	Shared Neighborhood Hits	49
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

FBLN2_HUMAN
NC score	0.059204 (rank : 141)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	132	Target Neighborhood Hits	392	Shared Neighborhood Hits	52
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

ZAN_HUMAN
NC score	0.058856 (rank : 142)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	132	Target Neighborhood Hits	679	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

C1QR1_HUMAN
NC score	0.058331 (rank : 143)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	132	Target Neighborhood Hits	493	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

LAMB2_MOUSE
NC score	0.057537 (rank : 144)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	132	Target Neighborhood Hits	722	Shared Neighborhood Hits	57
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

SUSD1_HUMAN
NC score	0.056792 (rank : 145)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	132	Target Neighborhood Hits	285	Shared Neighborhood Hits	46
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

NID2_MOUSE
NC score	0.056407 (rank : 146)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	132	Target Neighborhood Hits	338	Shared Neighborhood Hits	50
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

LAMA1_MOUSE
NC score	0.056238 (rank : 147)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	132	Target Neighborhood Hits	838	Shared Neighborhood Hits	60
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

HHIP_HUMAN
NC score	0.056096 (rank : 148)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	132	Target Neighborhood Hits	249	Shared Neighborhood Hits	51
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

CN155_HUMAN
NC score	0.055938 (rank : 149)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	132	Target Neighborhood Hits	385	Shared Neighborhood Hits	20
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

GAS6_MOUSE
NC score	0.055709 (rank : 150)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	132	Target Neighborhood Hits	343	Shared Neighborhood Hits	52
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

TRBM_HUMAN
NC score	0.055474 (rank : 151)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	132	Target Neighborhood Hits	339	Shared Neighborhood Hits	46
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

UROM_MOUSE
NC score	0.055420 (rank : 152)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	132	Target Neighborhood Hits	276	Shared Neighborhood Hits	50
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

HHIP_MOUSE
NC score	0.055411 (rank : 153)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	132	Target Neighborhood Hits	219	Shared Neighborhood Hits	50
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

GAS6_HUMAN
NC score	0.055107 (rank : 154)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	132	Target Neighborhood Hits	348	Shared Neighborhood Hits	51
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

TDGF1_MOUSE
NC score	0.055066 (rank : 155)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	132	Target Neighborhood Hits	146	Shared Neighborhood Hits	48
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

NID1_MOUSE
NC score	0.055040 (rank : 156)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	132	Target Neighborhood Hits	335	Shared Neighborhood Hits	52
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

LAMA5_HUMAN
NC score	0.054992 (rank : 157)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	132	Target Neighborhood Hits	976	Shared Neighborhood Hits	60
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

TRBM_MOUSE
NC score	0.054882 (rank : 158)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	132	Target Neighborhood Hits	361	Shared Neighborhood Hits	49
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

NID2_HUMAN
NC score	0.054627 (rank : 159)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	132	Target Neighborhood Hits	456	Shared Neighborhood Hits	57
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

SCUB3_MOUSE
NC score	0.054622 (rank : 160)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	132	Target Neighborhood Hits	442	Shared Neighborhood Hits	50
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
NC score	0.054610 (rank : 161)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	132	Target Neighborhood Hits	428	Shared Neighborhood Hits	48
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

PGBM_MOUSE
NC score	0.054565 (rank : 162)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	132	Target Neighborhood Hits	1073	Shared Neighborhood Hits	72
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

FBLN1_MOUSE
NC score	0.054555 (rank : 163)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	132	Target Neighborhood Hits	329	Shared Neighborhood Hits	48
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

UROM_HUMAN
NC score	0.054534 (rank : 164)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	132	Target Neighborhood Hits	284	Shared Neighborhood Hits	50
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

FBLN1_HUMAN
NC score	0.054510 (rank : 165)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	132	Target Neighborhood Hits	324	Shared Neighborhood Hits	45
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

PROS_MOUSE
NC score	0.054509 (rank : 166)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	132	Target Neighborhood Hits	330	Shared Neighborhood Hits	50
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

KR107_HUMAN
NC score	0.054508 (rank : 167)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	132	Target Neighborhood Hits	330	Shared Neighborhood Hits	43
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

PROS_HUMAN
NC score	0.054424 (rank : 168)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	132	Target Neighborhood Hits	340	Shared Neighborhood Hits	50
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

RUNX3_HUMAN
NC score	0.054314 (rank : 169)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	132	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

FBLN5_HUMAN
NC score	0.054172 (rank : 170)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	132	Target Neighborhood Hits	329	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

NID1_HUMAN
NC score	0.054153 (rank : 171)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	132	Target Neighborhood Hits	329	Shared Neighborhood Hits	48
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

KRA53_HUMAN
NC score	0.054152 (rank : 172)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	132	Target Neighborhood Hits	331	Shared Neighborhood Hits	43
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

HNF1A_HUMAN
NC score	0.054008 (rank : 173)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	132	Target Neighborhood Hits	193	Shared Neighborhood Hits	15
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

CREL1_HUMAN
NC score	0.053896 (rank : 174)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	132	Target Neighborhood Hits	441	Shared Neighborhood Hits	50
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LAMA1_HUMAN
NC score	0.053630 (rank : 175)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	132	Target Neighborhood Hits	804	Shared Neighborhood Hits	55
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

FBLN5_MOUSE
NC score	0.053586 (rank : 176)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	132	Target Neighborhood Hits	317	Shared Neighborhood Hits	54
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

LAMC1_MOUSE
NC score	0.053368 (rank : 177)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	132	Target Neighborhood Hits	856	Shared Neighborhood Hits	60
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LEUK_HUMAN
NC score	0.053146 (rank : 178)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	132	Target Neighborhood Hits	213	Shared Neighborhood Hits	21
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

FBLN4_HUMAN
NC score	0.053087 (rank : 179)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	132	Target Neighborhood Hits	278	Shared Neighborhood Hits	45
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

LAMC3_MOUSE
NC score	0.053084 (rank : 180)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	132	Target Neighborhood Hits	624	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MEGF8_HUMAN
NC score	0.053056 (rank : 181)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	132	Target Neighborhood Hits	528	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

CREL1_MOUSE
NC score	0.052858 (rank : 182)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	132	Target Neighborhood Hits	524	Shared Neighborhood Hits	50
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LAMC3_HUMAN
NC score	0.052774 (rank : 183)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	132	Target Neighborhood Hits	588	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

BSN_MOUSE
NC score	0.052767 (rank : 184)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	132	Target Neighborhood Hits	2057	Shared Neighborhood Hits	38
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MEGF8_MOUSE
NC score	0.052706 (rank : 185)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	132	Target Neighborhood Hits	520	Shared Neighborhood Hits	53
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

HNF1A_MOUSE
NC score	0.052694 (rank : 186)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	132	Target Neighborhood Hits	212	Shared Neighborhood Hits	13
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

KR104_HUMAN
NC score	0.052566 (rank : 187)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	132	Target Neighborhood Hits	313	Shared Neighborhood Hits	42
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

PO121_HUMAN
NC score	0.052237 (rank : 188)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	132	Target Neighborhood Hits	344	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

LAMC2_MOUSE
NC score	0.052101 (rank : 189)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	132	Target Neighborhood Hits	614	Shared Neighborhood Hits	60
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

CD248_MOUSE
NC score	0.052051 (rank : 190)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	132	Target Neighborhood Hits	578	Shared Neighborhood Hits	59
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

FBLN3_MOUSE
NC score	0.051978 (rank : 191)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	132	Target Neighborhood Hits	279	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN3_HUMAN
NC score	0.051747 (rank : 192)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	132	Target Neighborhood Hits	293	Shared Neighborhood Hits	46
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

TDGF2_HUMAN
NC score	0.051746 (rank : 193)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	132	Target Neighborhood Hits	131	Shared Neighborhood Hits	43
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

FBLN4_MOUSE
NC score	0.051547 (rank : 194)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	132	Target Neighborhood Hits	270	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

VLDLR_HUMAN
NC score	0.051474 (rank : 195)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	132	Target Neighborhood Hits	383	Shared Neighborhood Hits	48
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

SRRM1_HUMAN
NC score	0.051467 (rank : 196)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	132	Target Neighborhood Hits	690	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

TSP4_HUMAN
NC score	0.051439 (rank : 197)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	132	Target Neighborhood Hits	277	Shared Neighborhood Hits	49
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

KR106_HUMAN
NC score	0.051431 (rank : 198)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	132	Target Neighborhood Hits	347	Shared Neighborhood Hits	43
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

FATH_HUMAN
NC score	0.051418 (rank : 199)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	132	Target Neighborhood Hits	570	Shared Neighborhood Hits	69
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

TSP4_MOUSE
NC score	0.051395 (rank : 200)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	132	Target Neighborhood Hits	276	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

LDLR_MOUSE
NC score	0.051374 (rank : 201)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	132	Target Neighborhood Hits	382	Shared Neighborhood Hits	48
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_HUMAN
NC score	0.051353 (rank : 202)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	132	Target Neighborhood Hits	375	Shared Neighborhood Hits	45
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

VLDLR_MOUSE
NC score	0.050944 (rank : 203)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	132	Target Neighborhood Hits	360	Shared Neighborhood Hits	47
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LAMB1_MOUSE
NC score	0.050873 (rank : 204)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	132	Target Neighborhood Hits	919	Shared Neighborhood Hits	52
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

COMP_MOUSE
NC score	0.050863 (rank : 205)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	132	Target Neighborhood Hits	290	Shared Neighborhood Hits	52
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

KRA58_HUMAN
NC score	0.050568 (rank : 206)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	132	Target Neighborhood Hits	324	Shared Neighborhood Hits	42
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

NU214_HUMAN
NC score	0.050565 (rank : 207)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	132	Target Neighborhood Hits	657	Shared Neighborhood Hits	27
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

LAMC2_HUMAN
NC score	0.050411 (rank : 208)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	132	Target Neighborhood Hits	715	Shared Neighborhood Hits	58
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

BSN_HUMAN
NC score	0.050396 (rank : 209)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	132	Target Neighborhood Hits	1537	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PO121_MOUSE
NC score	0.050339 (rank : 210)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	132	Target Neighborhood Hits	345	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

TDGF1_HUMAN
NC score	0.050327 (rank : 211)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	132	Target Neighborhood Hits	132	Shared Neighborhood Hits	43
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

LAMB3_MOUSE
NC score	0.050105 (rank : 212)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	132	Target Neighborhood Hits	444	Shared Neighborhood Hits	54
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC1_HUMAN
NC score	0.050078 (rank : 213)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	132	Target Neighborhood Hits	922	Shared Neighborhood Hits	59
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LRP8_MOUSE
NC score	0.050043 (rank : 214)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	132	Target Neighborhood Hits	385	Shared Neighborhood Hits	45
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

PCQAP_HUMAN
NC score	0.049993 (rank : 215)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	132	Target Neighborhood Hits	549	Shared Neighborhood Hits	20
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

LYAM2_HUMAN
NC score	0.049966 (rank : 216)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	132	Target Neighborhood Hits	394	Shared Neighborhood Hits	63
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

PGCA_HUMAN
NC score	0.048644 (rank : 217)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	132	Target Neighborhood Hits	821	Shared Neighborhood Hits	67
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

BAT2_MOUSE
NC score	0.047535 (rank : 218)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	132	Target Neighborhood Hits	947	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

VASN_MOUSE
NC score	0.041515 (rank : 219)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	132	Target Neighborhood Hits	426	Shared Neighborhood Hits	53
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

FA12_HUMAN
NC score	0.041436 (rank : 220)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	132	Target Neighborhood Hits	425	Shared Neighborhood Hits	61
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

IER5_MOUSE
NC score	0.039082 (rank : 221)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	132	Target Neighborhood Hits	110	Shared Neighborhood Hits	9
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

TP53B_MOUSE
NC score	0.037202 (rank : 222)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	132	Target Neighborhood Hits	644	Shared Neighborhood Hits	28
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

GP112_HUMAN
NC score	0.036978 (rank : 223)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	132	Target Neighborhood Hits	441	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

TPA_MOUSE
NC score	0.036214 (rank : 224)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	132	Target Neighborhood Hits	335	Shared Neighborhood Hits	59
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TARA_HUMAN
NC score	0.035663 (rank : 225)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	132	Target Neighborhood Hits	1626	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TTLL7_HUMAN
NC score	0.034465 (rank : 226)	θ value	0.47712 (rank : 36)
Query Neighborhood Hits	132	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZT98, Q5TAX8, Q5TAX9, Q6P990, Q86YS1, Q9H5U4	Gene names	TTLL7
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 7 (Protein NYD-SP30).

TNR1B_MOUSE
NC score	0.032710 (rank : 227)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	132	Target Neighborhood Hits	123	Shared Neighborhood Hits	13
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

ANK2_HUMAN
NC score	0.031961 (rank : 228)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	132	Target Neighborhood Hits	1615	Shared Neighborhood Hits	37
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

PARP4_HUMAN
NC score	0.031274 (rank : 229)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	132	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

JTB_HUMAN
NC score	0.029337 (rank : 230)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	132	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	O76095, O95442	Gene names	JTB
Domain Architecture
Description	Protein JTB precursor (Jumping translocation breakpoint protein) (Prostate androgen-regulated protein) (PAR protein).

TMPS9_MOUSE
NC score	0.027411 (rank : 231)	θ value	0.0330416 (rank : 18)
Query Neighborhood Hits	132	Target Neighborhood Hits	296	Shared Neighborhood Hits	16
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

CEL_HUMAN
NC score	0.026615 (rank : 232)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	132	Target Neighborhood Hits	896	Shared Neighborhood Hits	17
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

SYNPO_HUMAN
NC score	0.026421 (rank : 233)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	132	Target Neighborhood Hits	281	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TSC1_HUMAN
NC score	0.024250 (rank : 234)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	132	Target Neighborhood Hits	765	Shared Neighborhood Hits	15
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

PDLI7_HUMAN
NC score	0.021954 (rank : 235)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	132	Target Neighborhood Hits	547	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

FETUB_MOUSE
NC score	0.021073 (rank : 236)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	132	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXC1	Gene names	Fetub
Domain Architecture
Description	Fetuin-B precursor (IRL685).

MPDZ_HUMAN
NC score	0.020938 (rank : 237)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	132	Target Neighborhood Hits	261	Shared Neighborhood Hits	5
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

RHG12_MOUSE
NC score	0.019690 (rank : 238)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	132	Target Neighborhood Hits	204	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CD45_HUMAN
NC score	0.018703 (rank : 239)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	132	Target Neighborhood Hits	243	Shared Neighborhood Hits	17
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

HSF1_MOUSE
NC score	0.017591 (rank : 240)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	132	Target Neighborhood Hits	267	Shared Neighborhood Hits	10
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

ADA32_MOUSE
NC score	0.016825 (rank : 241)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	132	Target Neighborhood Hits	219	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

CT075_HUMAN
NC score	0.016793 (rank : 242)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	132	Target Neighborhood Hits	387	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

KIFC1_HUMAN
NC score	0.015600 (rank : 243)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	132	Target Neighborhood Hits	545	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BW19, O60887, Q14834, Q9UQP7	Gene names	KIFC1, HSET, KNSL2
Domain Architecture
Description	Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET).

ENTK_MOUSE
NC score	0.015223 (rank : 244)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	132	Target Neighborhood Hits	338	Shared Neighborhood Hits	17
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

RHG25_HUMAN
NC score	0.012423 (rank : 245)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	132	Target Neighborhood Hits	550	Shared Neighborhood Hits	8
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CAC1B_MOUSE
NC score	0.011901 (rank : 246)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	132	Target Neighborhood Hits	351	Shared Neighborhood Hits	10
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

DMXL2_HUMAN
NC score	0.010593 (rank : 247)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	132	Target Neighborhood Hits	374	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TDJ6, O94938	Gene names	DMXL2, KIAA0856
Domain Architecture	No domain graphic available
Description	Protein DmX-like 2 (Rabconnectin-3).

SENP1_MOUSE
NC score	0.010359 (rank : 248)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	132	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

NDST3_MOUSE
NC score	0.007964 (rank : 249)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	132	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EQH7, Q6AXE0, Q9D557	Gene names	Ndst3, Hsst3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 3 (EC 2.8.2.-)].

PRP4B_MOUSE
NC score	0.007889 (rank : 250)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	132	Target Neighborhood Hits	1040	Shared Neighborhood Hits	10
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

PRP4B_HUMAN
NC score	0.006681 (rank : 251)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	132	Target Neighborhood Hits	1030	Shared Neighborhood Hits	10
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

POGZ_HUMAN
NC score	0.006323 (rank : 252)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	132	Target Neighborhood Hits	745	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z3K3, O75049, Q8TDZ7, Q9Y4X7	Gene names	POGZ, KIAA0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

SMC1A_MOUSE
NC score	0.004449 (rank : 253)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	132	Target Neighborhood Hits	1384	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

IPSP_MOUSE
NC score	0.003961 (rank : 254)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	132	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	P70458	Gene names	Serpina5, Pci
Domain Architecture
Description	Plasma serine protease inhibitor precursor (PCI) (Protein C inhibitor) (Serpin A5) (Plasminogen activator inhibitor 3) (PAI-3) (PAI3).

HMX3_MOUSE
NC score	0.003126 (rank : 255)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	132	Target Neighborhood Hits	342	Shared Neighborhood Hits	2
SwissProt Accessions	P42581	Gene names	Hmx3, Nkx-5.1, Nkx5-1
Domain Architecture
Description	Homeobox protein HMX3 (Homeobox protein Nkx-5.1).

MARK2_MOUSE
NC score	0.001870 (rank : 256)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	132	Target Neighborhood Hits	1018	Shared Neighborhood Hits	15
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).