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Network neighborhood for query Sequence : RUNX3_HUMAN

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RUNX3_HUMAN
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RUNX3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	96
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

RUNX3_MOUSE
θ value	0 (rank : 2)	NC score	0.978505 (rank : 2)
Query Neighborhood Hits	96	Target Neighborhood Hits	113	Shared Neighborhood Hits	45
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

RUNX1_HUMAN
θ value	4.15819e-130 (rank : 3)	NC score	0.957812 (rank : 4)
Query Neighborhood Hits	96	Target Neighborhood Hits	94	Shared Neighborhood Hits	17
SwissProt Accessions	Q01196, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479	Gene names	RUNX1, AML1, CBFA2
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

RUNX1_MOUSE
θ value	1.47893e-127 (rank : 4)	NC score	0.960016 (rank : 3)
Query Neighborhood Hits	96	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	Q03347, O08598, Q62049, Q9ESB9, Q9ET65	Gene names	Runx1, Aml1, Cbfa2, Pebp2ab
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

RUNX2_HUMAN
θ value	1.09934e-114 (rank : 5)	NC score	0.949771 (rank : 5)
Query Neighborhood Hits	96	Target Neighborhood Hits	103	Shared Neighborhood Hits	15
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

RUNX2_MOUSE
θ value	1.21547e-113 (rank : 6)	NC score	0.945060 (rank : 6)
Query Neighborhood Hits	96	Target Neighborhood Hits	119	Shared Neighborhood Hits	16
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

EP400_HUMAN
θ value	0.0193708 (rank : 7)	NC score	0.042405 (rank : 33)
Query Neighborhood Hits	96	Target Neighborhood Hits	556	Shared Neighborhood Hits	21
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

LPP_HUMAN
θ value	0.0736092 (rank : 8)	NC score	0.048937 (rank : 24)
Query Neighborhood Hits	96	Target Neighborhood Hits	775	Shared Neighborhood Hits	53
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

ATN1_HUMAN
θ value	0.0961366 (rank : 9)	NC score	0.074374 (rank : 7)
Query Neighborhood Hits	96	Target Neighborhood Hits	676	Shared Neighborhood Hits	32
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

PHF1_MOUSE
θ value	0.0961366 (rank : 10)	NC score	0.054459 (rank : 20)
Query Neighborhood Hits	96	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

ZIMP7_HUMAN
θ value	0.0961366 (rank : 11)	NC score	0.043980 (rank : 32)
Query Neighborhood Hits	96	Target Neighborhood Hits	290	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

CNOT3_MOUSE
θ value	0.125558 (rank : 12)	NC score	0.059089 (rank : 17)
Query Neighborhood Hits	96	Target Neighborhood Hits	504	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

HCN4_HUMAN
θ value	0.163984 (rank : 13)	NC score	0.032403 (rank : 45)
Query Neighborhood Hits	96	Target Neighborhood Hits	303	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

MILK1_MOUSE
θ value	0.163984 (rank : 14)	NC score	0.058814 (rank : 18)
Query Neighborhood Hits	96	Target Neighborhood Hits	788	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NRG3_MOUSE
θ value	0.163984 (rank : 15)	NC score	0.054314 (rank : 21)
Query Neighborhood Hits	96	Target Neighborhood Hits	132	Shared Neighborhood Hits	5
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

ATX2L_MOUSE
θ value	0.21417 (rank : 16)	NC score	0.062752 (rank : 15)
Query Neighborhood Hits	96	Target Neighborhood Hits	401	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

ENAH_MOUSE
θ value	0.21417 (rank : 17)	NC score	0.047213 (rank : 26)
Query Neighborhood Hits	96	Target Neighborhood Hits	919	Shared Neighborhood Hits	28
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

MUC2_HUMAN
θ value	0.21417 (rank : 18)	NC score	0.062001 (rank : 16)
Query Neighborhood Hits	96	Target Neighborhood Hits	906	Shared Neighborhood Hits	35
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

ZCH14_MOUSE
θ value	0.279714 (rank : 19)	NC score	0.066419 (rank : 11)
Query Neighborhood Hits	96	Target Neighborhood Hits	109	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

NRG3_HUMAN
θ value	0.365318 (rank : 20)	NC score	0.055558 (rank : 19)
Query Neighborhood Hits	96	Target Neighborhood Hits	119	Shared Neighborhood Hits	4
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

PCQAP_MOUSE
θ value	0.365318 (rank : 21)	NC score	0.046241 (rank : 27)
Query Neighborhood Hits	96	Target Neighborhood Hits	506	Shared Neighborhood Hits	18
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

RREB1_HUMAN
θ value	0.365318 (rank : 22)	NC score	0.010638 (rank : 84)
Query Neighborhood Hits	96	Target Neighborhood Hits	879	Shared Neighborhood Hits	13
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

SNPH_HUMAN
θ value	0.365318 (rank : 23)	NC score	0.032930 (rank : 44)
Query Neighborhood Hits	96	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	O15079	Gene names	SNPH, KIAA0374
Domain Architecture	No domain graphic available
Description	Syntaphilin.

MAST4_HUMAN
θ value	0.47712 (rank : 24)	NC score	0.018979 (rank : 66)
Query Neighborhood Hits	96	Target Neighborhood Hits	1804	Shared Neighborhood Hits	45
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

PDC6I_HUMAN
θ value	0.47712 (rank : 25)	NC score	0.035119 (rank : 41)
Query Neighborhood Hits	96	Target Neighborhood Hits	278	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PHF1_HUMAN
θ value	0.47712 (rank : 26)	NC score	0.047419 (rank : 25)
Query Neighborhood Hits	96	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

TBR1_MOUSE
θ value	0.47712 (rank : 27)	NC score	0.024555 (rank : 57)
Query Neighborhood Hits	96	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q64336	Gene names	Tbr1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

MAST1_HUMAN
θ value	0.62314 (rank : 28)	NC score	0.017428 (rank : 68)
Query Neighborhood Hits	96	Target Neighborhood Hits	1146	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
θ value	0.62314 (rank : 29)	NC score	0.017195 (rank : 69)
Query Neighborhood Hits	96	Target Neighborhood Hits	1123	Shared Neighborhood Hits	15
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

TBR1_HUMAN
θ value	0.62314 (rank : 30)	NC score	0.024185 (rank : 58)
Query Neighborhood Hits	96	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q16650, Q53TH0	Gene names	TBR1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

CTGE6_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.012216 (rank : 83)
Query Neighborhood Hits	96	Target Neighborhood Hits	650	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

RPB1_HUMAN
θ value	0.813845 (rank : 32)	NC score	0.070291 (rank : 9)
Query Neighborhood Hits	96	Target Neighborhood Hits	362	Shared Neighborhood Hits	28
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	0.813845 (rank : 33)	NC score	0.071225 (rank : 8)
Query Neighborhood Hits	96	Target Neighborhood Hits	363	Shared Neighborhood Hits	28
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

CCNK_MOUSE
θ value	1.06291 (rank : 34)	NC score	0.030846 (rank : 48)
Query Neighborhood Hits	96	Target Neighborhood Hits	350	Shared Neighborhood Hits	16
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

EPN1_MOUSE
θ value	1.06291 (rank : 35)	NC score	0.022485 (rank : 60)
Query Neighborhood Hits	96	Target Neighborhood Hits	240	Shared Neighborhood Hits	14
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

MAST2_HUMAN
θ value	1.06291 (rank : 36)	NC score	0.014652 (rank : 74)
Query Neighborhood Hits	96	Target Neighborhood Hits	1189	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST2_MOUSE
θ value	1.06291 (rank : 37)	NC score	0.014434 (rank : 75)
Query Neighborhood Hits	96	Target Neighborhood Hits	1110	Shared Neighborhood Hits	16
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MTMR7_MOUSE
θ value	1.06291 (rank : 38)	NC score	0.014021 (rank : 77)
Query Neighborhood Hits	96	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2C9, Q8C4J6	Gene names	Mtmr7
Domain Architecture
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

SYNPO_MOUSE
θ value	1.06291 (rank : 39)	NC score	0.040402 (rank : 34)
Query Neighborhood Hits	96	Target Neighborhood Hits	242	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

CN032_HUMAN
θ value	1.38821 (rank : 40)	NC score	0.045705 (rank : 30)
Query Neighborhood Hits	96	Target Neighborhood Hits	267	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

EGR1_MOUSE
θ value	1.38821 (rank : 41)	NC score	0.006848 (rank : 90)
Query Neighborhood Hits	96	Target Neighborhood Hits	816	Shared Neighborhood Hits	15
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

LRIG1_MOUSE
θ value	1.38821 (rank : 42)	NC score	0.004078 (rank : 95)
Query Neighborhood Hits	96	Target Neighborhood Hits	627	Shared Neighborhood Hits	4
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

MUC5B_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.028515 (rank : 53)
Query Neighborhood Hits	96	Target Neighborhood Hits	1020	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PTN23_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.016264 (rank : 72)
Query Neighborhood Hits	96	Target Neighborhood Hits	646	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

EGR1_HUMAN
θ value	1.81305 (rank : 45)	NC score	0.004958 (rank : 93)
Query Neighborhood Hits	96	Target Neighborhood Hits	788	Shared Neighborhood Hits	8
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

GCM2_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.024940 (rank : 56)
Query Neighborhood Hits	96	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	O75603	Gene names	GCM2, GCMB
Domain Architecture
Description	Chorion-specific transcription factor GCMb (Glial cells missing homolog 2) (GCM motif protein 2) (hGCMb).

MLL3_HUMAN
θ value	1.81305 (rank : 47)	NC score	0.035765 (rank : 38)
Query Neighborhood Hits	96	Target Neighborhood Hits	1644	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PRDM2_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.009623 (rank : 86)
Query Neighborhood Hits	96	Target Neighborhood Hits	1135	Shared Neighborhood Hits	19
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

RGPD8_HUMAN
θ value	1.81305 (rank : 49)	NC score	0.012542 (rank : 82)
Query Neighborhood Hits	96	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

SON_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.031066 (rank : 47)
Query Neighborhood Hits	96	Target Neighborhood Hits	957	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

ZIMP7_MOUSE
θ value	1.81305 (rank : 51)	NC score	0.044298 (rank : 31)
Query Neighborhood Hits	96	Target Neighborhood Hits	566	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

CT151_HUMAN
θ value	2.36792 (rank : 52)	NC score	0.028859 (rank : 51)
Query Neighborhood Hits	96	Target Neighborhood Hits	382	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

EWS_MOUSE
θ value	2.36792 (rank : 53)	NC score	0.036545 (rank : 36)
Query Neighborhood Hits	96	Target Neighborhood Hits	271	Shared Neighborhood Hits	13
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

LZTS2_MOUSE
θ value	2.36792 (rank : 54)	NC score	0.013004 (rank : 79)
Query Neighborhood Hits	96	Target Neighborhood Hits	423	Shared Neighborhood Hits	9
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

AB1IP_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.022351 (rank : 61)
Query Neighborhood Hits	96	Target Neighborhood Hits	213	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ATX2L_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.063261 (rank : 13)
Query Neighborhood Hits	96	Target Neighborhood Hits	443	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

HCN4_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.033233 (rank : 43)
Query Neighborhood Hits	96	Target Neighborhood Hits	284	Shared Neighborhood Hits	18
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HSPB8_MOUSE
θ value	3.0926 (rank : 58)	NC score	0.016217 (rank : 73)
Query Neighborhood Hits	96	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JK92	Gene names	Hspb8, Cryac, Hsp22
Domain Architecture
Description	Heat-shock protein beta-8 (HspB8) (Alpha crystallin C chain) (Small stress protein-like protein HSP22).

PITM1_MOUSE
θ value	3.0926 (rank : 59)	NC score	0.010333 (rank : 85)
Query Neighborhood Hits	96	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	O35954	Gene names	Pitpnm1, Dres9, Mpt1, Nir2, Pitpnm
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Mpt-1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog 1) (RdgB1).

SMAD1_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.009175 (rank : 87)
Query Neighborhood Hits	96	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

SPT5H_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.045937 (rank : 28)
Query Neighborhood Hits	96	Target Neighborhood Hits	436	Shared Neighborhood Hits	40
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	3.0926 (rank : 62)	NC score	0.045904 (rank : 29)
Query Neighborhood Hits	96	Target Neighborhood Hits	437	Shared Neighborhood Hits	40
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SRRM2_HUMAN
θ value	3.0926 (rank : 63)	NC score	0.062795 (rank : 14)
Query Neighborhood Hits	96	Target Neighborhood Hits	1296	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	3.0926 (rank : 64)	NC score	0.063482 (rank : 12)
Query Neighborhood Hits	96	Target Neighborhood Hits	1470	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SYN2_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.016449 (rank : 71)
Query Neighborhood Hits	96	Target Neighborhood Hits	213	Shared Neighborhood Hits	12
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

SYNJ1_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.026246 (rank : 55)
Query Neighborhood Hits	96	Target Neighborhood Hits	498	Shared Neighborhood Hits	28
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYNJ1_MOUSE
θ value	3.0926 (rank : 67)	NC score	0.028776 (rank : 52)
Query Neighborhood Hits	96	Target Neighborhood Hits	516	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TARA_MOUSE
θ value	3.0926 (rank : 68)	NC score	0.021147 (rank : 62)
Query Neighborhood Hits	96	Target Neighborhood Hits	1133	Shared Neighborhood Hits	30
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TS101_MOUSE
θ value	3.0926 (rank : 69)	NC score	0.029466 (rank : 50)
Query Neighborhood Hits	96	Target Neighborhood Hits	312	Shared Neighborhood Hits	5
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

WASIP_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.029860 (rank : 49)
Query Neighborhood Hits	96	Target Neighborhood Hits	458	Shared Neighborhood Hits	27
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

CI079_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.028024 (rank : 54)
Query Neighborhood Hits	96	Target Neighborhood Hits	288	Shared Neighborhood Hits	21
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CNOT3_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.049638 (rank : 23)
Query Neighborhood Hits	96	Target Neighborhood Hits	425	Shared Neighborhood Hits	18
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

HGS_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.035389 (rank : 40)
Query Neighborhood Hits	96	Target Neighborhood Hits	589	Shared Neighborhood Hits	28
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

MAGC1_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.035655 (rank : 39)
Query Neighborhood Hits	96	Target Neighborhood Hits	431	Shared Neighborhood Hits	26
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

NU214_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.036496 (rank : 37)
Query Neighborhood Hits	96	Target Neighborhood Hits	657	Shared Neighborhood Hits	30
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

CIC_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.032302 (rank : 46)
Query Neighborhood Hits	96	Target Neighborhood Hits	992	Shared Neighborhood Hits	47
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

EWS_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.021024 (rank : 64)
Query Neighborhood Hits	96	Target Neighborhood Hits	249	Shared Neighborhood Hits	11
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

FGD1_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.006698 (rank : 91)
Query Neighborhood Hits	96	Target Neighborhood Hits	367	Shared Neighborhood Hits	13
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

NFRKB_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.023859 (rank : 59)
Query Neighborhood Hits	96	Target Neighborhood Hits	211	Shared Neighborhood Hits	14
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

AP2B_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.012790 (rank : 80)
Query Neighborhood Hits	96	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q92481, Q5JYX6, Q9NQ63, Q9NU99, Q9UJI7, Q9Y214, Q9Y3K3	Gene names	TFAP2B
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

AP2B_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.012777 (rank : 81)
Query Neighborhood Hits	96	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q61313	Gene names	Tfap2b, Tcfap2b
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

GSCR1_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.038937 (rank : 35)
Query Neighborhood Hits	96	Target Neighborhood Hits	674	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

MLL2_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.033362 (rank : 42)
Query Neighborhood Hits	96	Target Neighborhood Hits	1788	Shared Neighborhood Hits	48
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NKTR_MOUSE
θ value	6.88961 (rank : 84)	NC score	0.007328 (rank : 89)
Query Neighborhood Hits	96	Target Neighborhood Hits	417	Shared Neighborhood Hits	10
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PCLO_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.021061 (rank : 63)
Query Neighborhood Hits	96	Target Neighborhood Hits	2275	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PGCA_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.008452 (rank : 88)
Query Neighborhood Hits	96	Target Neighborhood Hits	643	Shared Neighborhood Hits	16
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

RNC_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.019453 (rank : 65)
Query Neighborhood Hits	96	Target Neighborhood Hits	176	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

WBS14_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.014134 (rank : 76)
Query Neighborhood Hits	96	Target Neighborhood Hits	171	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

IDD_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.017903 (rank : 67)
Query Neighborhood Hits	96	Target Neighborhood Hits	127	Shared Neighborhood Hits	4
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

MCR_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.002591 (rank : 98)
Query Neighborhood Hits	96	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

NKX61_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.002745 (rank : 97)
Query Neighborhood Hits	96	Target Neighborhood Hits	431	Shared Neighborhood Hits	9
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

PLXB1_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.004222 (rank : 94)
Query Neighborhood Hits	96	Target Neighborhood Hits	259	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

RTN4R_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.002757 (rank : 96)
Query Neighborhood Hits	96	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZR6	Gene names	RTN4R, NOGOR
Domain Architecture
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

TBX19_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.013533 (rank : 78)
Query Neighborhood Hits	96	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q99ME7	Gene names	Tbx19, Tpit
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

TS101_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.016517 (rank : 70)
Query Neighborhood Hits	96	Target Neighborhood Hits	359	Shared Neighborhood Hits	5
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

ZDHC8_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.006349 (rank : 92)
Query Neighborhood Hits	96	Target Neighborhood Hits	243	Shared Neighborhood Hits	10
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

ARI1A_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.068605 (rank : 10)
Query Neighborhood Hits	96	Target Neighborhood Hits	787	Shared Neighborhood Hits	39
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ATX2_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.051137 (rank : 22)
Query Neighborhood Hits	96	Target Neighborhood Hits	445	Shared Neighborhood Hits	41
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

Hits sorted by NC score

RUNX3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	96
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

RUNX3_MOUSE
NC score	0.978505 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	96	Target Neighborhood Hits	113	Shared Neighborhood Hits	45
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

RUNX1_MOUSE
NC score	0.960016 (rank : 3)	θ value	1.47893e-127 (rank : 4)
Query Neighborhood Hits	96	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	Q03347, O08598, Q62049, Q9ESB9, Q9ET65	Gene names	Runx1, Aml1, Cbfa2, Pebp2ab
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

RUNX1_HUMAN
NC score	0.957812 (rank : 4)	θ value	4.15819e-130 (rank : 3)
Query Neighborhood Hits	96	Target Neighborhood Hits	94	Shared Neighborhood Hits	17
SwissProt Accessions	Q01196, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479	Gene names	RUNX1, AML1, CBFA2
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

RUNX2_HUMAN
NC score	0.949771 (rank : 5)	θ value	1.09934e-114 (rank : 5)
Query Neighborhood Hits	96	Target Neighborhood Hits	103	Shared Neighborhood Hits	15
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

RUNX2_MOUSE
NC score	0.945060 (rank : 6)	θ value	1.21547e-113 (rank : 6)
Query Neighborhood Hits	96	Target Neighborhood Hits	119	Shared Neighborhood Hits	16
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

ATN1_HUMAN
NC score	0.074374 (rank : 7)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	96	Target Neighborhood Hits	676	Shared Neighborhood Hits	32
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

RPB1_MOUSE
NC score	0.071225 (rank : 8)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	96	Target Neighborhood Hits	363	Shared Neighborhood Hits	28
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.070291 (rank : 9)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	96	Target Neighborhood Hits	362	Shared Neighborhood Hits	28
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

ARI1A_HUMAN
NC score	0.068605 (rank : 10)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	96	Target Neighborhood Hits	787	Shared Neighborhood Hits	39
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ZCH14_MOUSE
NC score	0.066419 (rank : 11)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	96	Target Neighborhood Hits	109	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

SRRM2_MOUSE
NC score	0.063482 (rank : 12)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	96	Target Neighborhood Hits	1470	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ATX2L_HUMAN
NC score	0.063261 (rank : 13)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	96	Target Neighborhood Hits	443	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

SRRM2_HUMAN
NC score	0.062795 (rank : 14)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	96	Target Neighborhood Hits	1296	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ATX2L_MOUSE
NC score	0.062752 (rank : 15)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	96	Target Neighborhood Hits	401	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

MUC2_HUMAN
NC score	0.062001 (rank : 16)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	96	Target Neighborhood Hits	906	Shared Neighborhood Hits	35
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

CNOT3_MOUSE
NC score	0.059089 (rank : 17)	θ value	0.125558 (rank : 12)
Query Neighborhood Hits	96	Target Neighborhood Hits	504	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

MILK1_MOUSE
NC score	0.058814 (rank : 18)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	96	Target Neighborhood Hits	788	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NRG3_HUMAN
NC score	0.055558 (rank : 19)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	96	Target Neighborhood Hits	119	Shared Neighborhood Hits	4
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

PHF1_MOUSE
NC score	0.054459 (rank : 20)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	96	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

NRG3_MOUSE
NC score	0.054314 (rank : 21)	θ value	0.163984 (rank : 15)
Query Neighborhood Hits	96	Target Neighborhood Hits	132	Shared Neighborhood Hits	5
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

ATX2_MOUSE
NC score	0.051137 (rank : 22)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	96	Target Neighborhood Hits	445	Shared Neighborhood Hits	41
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

CNOT3_HUMAN
NC score	0.049638 (rank : 23)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	96	Target Neighborhood Hits	425	Shared Neighborhood Hits	18
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

LPP_HUMAN
NC score	0.048937 (rank : 24)	θ value	0.0736092 (rank : 8)
Query Neighborhood Hits	96	Target Neighborhood Hits	775	Shared Neighborhood Hits	53
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

PHF1_HUMAN
NC score	0.047419 (rank : 25)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	96	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

ENAH_MOUSE
NC score	0.047213 (rank : 26)	θ value	0.21417 (rank : 17)
Query Neighborhood Hits	96	Target Neighborhood Hits	919	Shared Neighborhood Hits	28
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

PCQAP_MOUSE
NC score	0.046241 (rank : 27)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	96	Target Neighborhood Hits	506	Shared Neighborhood Hits	18
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

SPT5H_HUMAN
NC score	0.045937 (rank : 28)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	96	Target Neighborhood Hits	436	Shared Neighborhood Hits	40
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
NC score	0.045904 (rank : 29)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	96	Target Neighborhood Hits	437	Shared Neighborhood Hits	40
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

CN032_HUMAN
NC score	0.045705 (rank : 30)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	96	Target Neighborhood Hits	267	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

ZIMP7_MOUSE
NC score	0.044298 (rank : 31)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	96	Target Neighborhood Hits	566	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZIMP7_HUMAN
NC score	0.043980 (rank : 32)	θ value	0.0961366 (rank : 11)
Query Neighborhood Hits	96	Target Neighborhood Hits	290	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

EP400_HUMAN
NC score	0.042405 (rank : 33)	θ value	0.0193708 (rank : 7)
Query Neighborhood Hits	96	Target Neighborhood Hits	556	Shared Neighborhood Hits	21
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

SYNPO_MOUSE
NC score	0.040402 (rank : 34)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	96	Target Neighborhood Hits	242	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

GSCR1_HUMAN
NC score	0.038937 (rank : 35)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	96	Target Neighborhood Hits	674	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

EWS_MOUSE
NC score	0.036545 (rank : 36)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	96	Target Neighborhood Hits	271	Shared Neighborhood Hits	13
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

NU214_HUMAN
NC score	0.036496 (rank : 37)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	96	Target Neighborhood Hits	657	Shared Neighborhood Hits	30
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

MLL3_HUMAN
NC score	0.035765 (rank : 38)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	96	Target Neighborhood Hits	1644	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MAGC1_HUMAN
NC score	0.035655 (rank : 39)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	96	Target Neighborhood Hits	431	Shared Neighborhood Hits	26
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

HGS_MOUSE
NC score	0.035389 (rank : 40)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	96	Target Neighborhood Hits	589	Shared Neighborhood Hits	28
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

PDC6I_HUMAN
NC score	0.035119 (rank : 41)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	96	Target Neighborhood Hits	278	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

MLL2_HUMAN
NC score	0.033362 (rank : 42)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	96	Target Neighborhood Hits	1788	Shared Neighborhood Hits	48
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

HCN4_MOUSE
NC score	0.033233 (rank : 43)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	96	Target Neighborhood Hits	284	Shared Neighborhood Hits	18
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

SNPH_HUMAN
NC score	0.032930 (rank : 44)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	96	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	O15079	Gene names	SNPH, KIAA0374
Domain Architecture	No domain graphic available
Description	Syntaphilin.

HCN4_HUMAN
NC score	0.032403 (rank : 45)	θ value	0.163984 (rank : 13)
Query Neighborhood Hits	96	Target Neighborhood Hits	303	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

CIC_HUMAN
NC score	0.032302 (rank : 46)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	96	Target Neighborhood Hits	992	Shared Neighborhood Hits	47
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SON_MOUSE
NC score	0.031066 (rank : 47)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	96	Target Neighborhood Hits	957	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

CCNK_MOUSE
NC score	0.030846 (rank : 48)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	96	Target Neighborhood Hits	350	Shared Neighborhood Hits	16
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

WASIP_HUMAN
NC score	0.029860 (rank : 49)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	96	Target Neighborhood Hits	458	Shared Neighborhood Hits	27
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

TS101_MOUSE
NC score	0.029466 (rank : 50)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	96	Target Neighborhood Hits	312	Shared Neighborhood Hits	5
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

CT151_HUMAN
NC score	0.028859 (rank : 51)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	96	Target Neighborhood Hits	382	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

SYNJ1_MOUSE
NC score	0.028776 (rank : 52)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	96	Target Neighborhood Hits	516	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

MUC5B_HUMAN
NC score	0.028515 (rank : 53)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	96	Target Neighborhood Hits	1020	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

CI079_HUMAN
NC score	0.028024 (rank : 54)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	96	Target Neighborhood Hits	288	Shared Neighborhood Hits	21
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

SYNJ1_HUMAN
NC score	0.026246 (rank : 55)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	96	Target Neighborhood Hits	498	Shared Neighborhood Hits	28
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

GCM2_HUMAN
NC score	0.024940 (rank : 56)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	96	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	O75603	Gene names	GCM2, GCMB
Domain Architecture
Description	Chorion-specific transcription factor GCMb (Glial cells missing homolog 2) (GCM motif protein 2) (hGCMb).

TBR1_MOUSE
NC score	0.024555 (rank : 57)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	96	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q64336	Gene names	Tbr1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

TBR1_HUMAN
NC score	0.024185 (rank : 58)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	96	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q16650, Q53TH0	Gene names	TBR1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

NFRKB_HUMAN
NC score	0.023859 (rank : 59)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	96	Target Neighborhood Hits	211	Shared Neighborhood Hits	14
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

EPN1_MOUSE
NC score	0.022485 (rank : 60)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	96	Target Neighborhood Hits	240	Shared Neighborhood Hits	14
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

AB1IP_HUMAN
NC score	0.022351 (rank : 61)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	96	Target Neighborhood Hits	213	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

TARA_MOUSE
NC score	0.021147 (rank : 62)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	96	Target Neighborhood Hits	1133	Shared Neighborhood Hits	30
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PCLO_MOUSE
NC score	0.021061 (rank : 63)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	96	Target Neighborhood Hits	2275	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

EWS_HUMAN
NC score	0.021024 (rank : 64)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	96	Target Neighborhood Hits	249	Shared Neighborhood Hits	11
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

RNC_HUMAN
NC score	0.019453 (rank : 65)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	96	Target Neighborhood Hits	176	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

MAST4_HUMAN
NC score	0.018979 (rank : 66)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	96	Target Neighborhood Hits	1804	Shared Neighborhood Hits	45
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

IDD_HUMAN
NC score	0.017903 (rank : 67)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	96	Target Neighborhood Hits	127	Shared Neighborhood Hits	4
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

MAST1_HUMAN
NC score	0.017428 (rank : 68)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	96	Target Neighborhood Hits	1146	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
NC score	0.017195 (rank : 69)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	96	Target Neighborhood Hits	1123	Shared Neighborhood Hits	15
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

TS101_HUMAN
NC score	0.016517 (rank : 70)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	96	Target Neighborhood Hits	359	Shared Neighborhood Hits	5
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

SYN2_HUMAN
NC score	0.016449 (rank : 71)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	96	Target Neighborhood Hits	213	Shared Neighborhood Hits	12
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

PTN23_HUMAN
NC score	0.016264 (rank : 72)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	96	Target Neighborhood Hits	646	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

HSPB8_MOUSE
NC score	0.016217 (rank : 73)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	96	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JK92	Gene names	Hspb8, Cryac, Hsp22
Domain Architecture
Description	Heat-shock protein beta-8 (HspB8) (Alpha crystallin C chain) (Small stress protein-like protein HSP22).

MAST2_HUMAN
NC score	0.014652 (rank : 74)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	96	Target Neighborhood Hits	1189	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST2_MOUSE
NC score	0.014434 (rank : 75)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	96	Target Neighborhood Hits	1110	Shared Neighborhood Hits	16
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

WBS14_MOUSE
NC score	0.014134 (rank : 76)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	96	Target Neighborhood Hits	171	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

MTMR7_MOUSE
NC score	0.014021 (rank : 77)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	96	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2C9, Q8C4J6	Gene names	Mtmr7
Domain Architecture
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

TBX19_MOUSE
NC score	0.013533 (rank : 78)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	96	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q99ME7	Gene names	Tbx19, Tpit
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX19 (T-box protein 19) (T-box factor, pituitary).

LZTS2_MOUSE
NC score	0.013004 (rank : 79)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	96	Target Neighborhood Hits	423	Shared Neighborhood Hits	9
SwissProt Accessions	Q91YU6, Q569X6	Gene names	Lzts2, Kiaa1813
Domain Architecture
Description	Leucine zipper putative tumor suppressor 2.

AP2B_HUMAN
NC score	0.012790 (rank : 80)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	96	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q92481, Q5JYX6, Q9NQ63, Q9NU99, Q9UJI7, Q9Y214, Q9Y3K3	Gene names	TFAP2B
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

AP2B_MOUSE
NC score	0.012777 (rank : 81)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	96	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q61313	Gene names	Tfap2b, Tcfap2b
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

RGPD8_HUMAN
NC score	0.012542 (rank : 82)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	96	Target Neighborhood Hits	135	Shared Neighborhood Hits	4
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

CTGE6_HUMAN
NC score	0.012216 (rank : 83)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	96	Target Neighborhood Hits	650	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

RREB1_HUMAN
NC score	0.010638 (rank : 84)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	96	Target Neighborhood Hits	879	Shared Neighborhood Hits	13
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

PITM1_MOUSE
NC score	0.010333 (rank : 85)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	96	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	O35954	Gene names	Pitpnm1, Dres9, Mpt1, Nir2, Pitpnm
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Mpt-1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog 1) (RdgB1).

PRDM2_HUMAN
NC score	0.009623 (rank : 86)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	96	Target Neighborhood Hits	1135	Shared Neighborhood Hits	19
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SMAD1_HUMAN
NC score	0.009175 (rank : 87)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	96	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

PGCA_MOUSE
NC score	0.008452 (rank : 88)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	96	Target Neighborhood Hits	643	Shared Neighborhood Hits	16
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

NKTR_MOUSE
NC score	0.007328 (rank : 89)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	96	Target Neighborhood Hits	417	Shared Neighborhood Hits	10
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

EGR1_MOUSE
NC score	0.006848 (rank : 90)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	96	Target Neighborhood Hits	816	Shared Neighborhood Hits	15
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

FGD1_HUMAN
NC score	0.006698 (rank : 91)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	96	Target Neighborhood Hits	367	Shared Neighborhood Hits	13
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

ZDHC8_MOUSE
NC score	0.006349 (rank : 92)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	96	Target Neighborhood Hits	243	Shared Neighborhood Hits	10
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

EGR1_HUMAN
NC score	0.004958 (rank : 93)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	96	Target Neighborhood Hits	788	Shared Neighborhood Hits	8
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

PLXB1_MOUSE
NC score	0.004222 (rank : 94)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	96	Target Neighborhood Hits	259	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

LRIG1_MOUSE
NC score	0.004078 (rank : 95)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	96	Target Neighborhood Hits	627	Shared Neighborhood Hits	4
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

RTN4R_HUMAN
NC score	0.002757 (rank : 96)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	96	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZR6	Gene names	RTN4R, NOGOR
Domain Architecture
Description	Reticulon-4 receptor precursor (Nogo receptor) (NgR) (Nogo-66 receptor).

NKX61_HUMAN
NC score	0.002745 (rank : 97)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	96	Target Neighborhood Hits	431	Shared Neighborhood Hits	9
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

MCR_MOUSE
NC score	0.002591 (rank : 98)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	96	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).