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Network neighborhood for query Sequence : PHF1_MOUSE

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PHF1_MOUSE
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PHF1_HUMAN
θ value	0 (rank : 1)	NC score	0.991078 (rank : 2)
Query Neighborhood Hits	116	Target Neighborhood Hits	117	Shared Neighborhood Hits	95
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	116	Target Neighborhood Hits	116	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

MTF2_HUMAN
θ value	2.00813e-108 (rank : 3)	NC score	0.920378 (rank : 3)
Query Neighborhood Hits	116	Target Neighborhood Hits	119	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
θ value	2.6227e-108 (rank : 4)	NC score	0.918630 (rank : 4)
Query Neighborhood Hits	116	Target Neighborhood Hits	126	Shared Neighborhood Hits	71
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

PHF22_MOUSE
θ value	1.99992e-07 (rank : 5)	NC score	0.418163 (rank : 5)
Query Neighborhood Hits	116	Target Neighborhood Hits	89	Shared Neighborhood Hits	35
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

JADE3_HUMAN
θ value	3.41135e-07 (rank : 6)	NC score	0.392168 (rank : 6)
Query Neighborhood Hits	116	Target Neighborhood Hits	148	Shared Neighborhood Hits	59
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE2_HUMAN
θ value	7.59969e-07 (rank : 7)	NC score	0.385496 (rank : 8)
Query Neighborhood Hits	116	Target Neighborhood Hits	199	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
θ value	7.59969e-07 (rank : 8)	NC score	0.366871 (rank : 12)
Query Neighborhood Hits	116	Target Neighborhood Hits	560	Shared Neighborhood Hits	66
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

JADE3_MOUSE
θ value	7.59969e-07 (rank : 9)	NC score	0.389031 (rank : 7)
Query Neighborhood Hits	116	Target Neighborhood Hits	174	Shared Neighborhood Hits	59
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

PHF22_HUMAN
θ value	2.21117e-06 (rank : 10)	NC score	0.378665 (rank : 9)
Query Neighborhood Hits	116	Target Neighborhood Hits	121	Shared Neighborhood Hits	35
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

BRPF1_HUMAN
θ value	2.88788e-06 (rank : 11)	NC score	0.340154 (rank : 13)
Query Neighborhood Hits	116	Target Neighborhood Hits	259	Shared Neighborhood Hits	60
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

HRX_HUMAN
θ value	6.43352e-06 (rank : 12)	NC score	0.252079 (rank : 22)
Query Neighborhood Hits	116	Target Neighborhood Hits	825	Shared Neighborhood Hits	68
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

JADE1_HUMAN
θ value	8.40245e-06 (rank : 13)	NC score	0.377650 (rank : 10)
Query Neighborhood Hits	116	Target Neighborhood Hits	140	Shared Neighborhood Hits	56
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
θ value	8.40245e-06 (rank : 14)	NC score	0.377015 (rank : 11)
Query Neighborhood Hits	116	Target Neighborhood Hits	160	Shared Neighborhood Hits	56
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

MLL4_HUMAN
θ value	1.09739e-05 (rank : 15)	NC score	0.249516 (rank : 24)
Query Neighborhood Hits	116	Target Neighborhood Hits	722	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

CSR2B_HUMAN
θ value	3.19293e-05 (rank : 16)	NC score	0.338312 (rank : 14)
Query Neighborhood Hits	116	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H8E8, Q96GW6, Q96IH3, Q9HBF0, Q9UIY5	Gene names	CSRP2BP
Domain Architecture
Description	Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (CRP2BP) (CRP2-binding partner).

BRD1_HUMAN
θ value	5.44631e-05 (rank : 17)	NC score	0.325751 (rank : 15)
Query Neighborhood Hits	116	Target Neighborhood Hits	188	Shared Neighborhood Hits	58
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF3_HUMAN
θ value	0.00035302 (rank : 18)	NC score	0.309206 (rank : 16)
Query Neighborhood Hits	116	Target Neighborhood Hits	217	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

TRI66_MOUSE
θ value	0.000786445 (rank : 19)	NC score	0.241525 (rank : 25)
Query Neighborhood Hits	116	Target Neighborhood Hits	491	Shared Neighborhood Hits	58
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

CAC1B_MOUSE
θ value	0.00134147 (rank : 20)	NC score	0.036114 (rank : 138)
Query Neighborhood Hits	116	Target Neighborhood Hits	351	Shared Neighborhood Hits	7
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

LY10_HUMAN
θ value	0.00298849 (rank : 21)	NC score	0.222788 (rank : 31)
Query Neighborhood Hits	116	Target Neighborhood Hits	151	Shared Neighborhood Hits	47
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

TIF1A_HUMAN
θ value	0.00390308 (rank : 22)	NC score	0.222814 (rank : 30)
Query Neighborhood Hits	116	Target Neighborhood Hits	327	Shared Neighborhood Hits	57
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	0.00509761 (rank : 23)	NC score	0.225817 (rank : 29)
Query Neighborhood Hits	116	Target Neighborhood Hits	307	Shared Neighborhood Hits	58
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1B_HUMAN
θ value	0.00509761 (rank : 24)	NC score	0.235720 (rank : 27)
Query Neighborhood Hits	116	Target Neighborhood Hits	312	Shared Neighborhood Hits	55
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	0.00665767 (rank : 25)	NC score	0.238301 (rank : 26)
Query Neighborhood Hits	116	Target Neighborhood Hits	276	Shared Neighborhood Hits	55
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TRI66_HUMAN
θ value	0.00665767 (rank : 26)	NC score	0.227869 (rank : 28)
Query Neighborhood Hits	116	Target Neighborhood Hits	479	Shared Neighborhood Hits	56
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TIF1G_HUMAN
θ value	0.0148317 (rank : 27)	NC score	0.207632 (rank : 36)
Query Neighborhood Hits	116	Target Neighborhood Hits	410	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	0.0148317 (rank : 28)	NC score	0.207945 (rank : 35)
Query Neighborhood Hits	116	Target Neighborhood Hits	498	Shared Neighborhood Hits	60
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

AIRE_HUMAN
θ value	0.0252991 (rank : 29)	NC score	0.249918 (rank : 23)
Query Neighborhood Hits	116	Target Neighborhood Hits	144	Shared Neighborhood Hits	56
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

MLL2_HUMAN
θ value	0.0330416 (rank : 30)	NC score	0.177030 (rank : 44)
Query Neighborhood Hits	116	Target Neighborhood Hits	1788	Shared Neighborhood Hits	90
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SP110_HUMAN
θ value	0.0431538 (rank : 31)	NC score	0.180998 (rank : 42)
Query Neighborhood Hits	116	Target Neighborhood Hits	141	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

PARM1_MOUSE
θ value	0.0736092 (rank : 32)	NC score	0.063703 (rank : 108)
Query Neighborhood Hits	116	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

PF21A_MOUSE
θ value	0.0736092 (rank : 33)	NC score	0.219096 (rank : 33)
Query Neighborhood Hits	116	Target Neighborhood Hits	285	Shared Neighborhood Hits	59
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

CXCC1_HUMAN
θ value	0.0961366 (rank : 34)	NC score	0.150373 (rank : 59)
Query Neighborhood Hits	116	Target Neighborhood Hits	143	Shared Neighborhood Hits	36
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

PF21A_HUMAN
θ value	0.0961366 (rank : 35)	NC score	0.215171 (rank : 34)
Query Neighborhood Hits	116	Target Neighborhood Hits	303	Shared Neighborhood Hits	59
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

RUNX3_HUMAN
θ value	0.0961366 (rank : 36)	NC score	0.054459 (rank : 122)
Query Neighborhood Hits	116	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

CXCC1_MOUSE
θ value	0.125558 (rank : 37)	NC score	0.147706 (rank : 61)
Query Neighborhood Hits	116	Target Neighborhood Hits	124	Shared Neighborhood Hits	35
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

K1718_HUMAN
θ value	0.125558 (rank : 38)	NC score	0.113478 (rank : 79)
Query Neighborhood Hits	116	Target Neighborhood Hits	114	Shared Neighborhood Hits	21
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

MLL3_HUMAN
θ value	0.125558 (rank : 39)	NC score	0.167381 (rank : 49)
Query Neighborhood Hits	116	Target Neighborhood Hits	1644	Shared Neighborhood Hits	83
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	0.125558 (rank : 40)	NC score	0.175889 (rank : 45)
Query Neighborhood Hits	116	Target Neighborhood Hits	1399	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

BAZ2A_MOUSE
θ value	0.163984 (rank : 41)	NC score	0.184042 (rank : 38)
Query Neighborhood Hits	116	Target Neighborhood Hits	744	Shared Neighborhood Hits	62
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

JAD1A_HUMAN
θ value	0.163984 (rank : 42)	NC score	0.142357 (rank : 62)
Query Neighborhood Hits	116	Target Neighborhood Hits	328	Shared Neighborhood Hits	68
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

TCF19_HUMAN
θ value	0.163984 (rank : 43)	NC score	0.129754 (rank : 71)
Query Neighborhood Hits	116	Target Neighborhood Hits	124	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

K1718_MOUSE
θ value	0.21417 (rank : 44)	NC score	0.111720 (rank : 81)
Query Neighborhood Hits	116	Target Neighborhood Hits	98	Shared Neighborhood Hits	21
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

REQU_HUMAN
θ value	0.21417 (rank : 45)	NC score	0.184291 (rank : 37)
Query Neighborhood Hits	116	Target Neighborhood Hits	523	Shared Neighborhood Hits	58
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

AF17_HUMAN
θ value	0.279714 (rank : 46)	NC score	0.257587 (rank : 20)
Query Neighborhood Hits	116	Target Neighborhood Hits	230	Shared Neighborhood Hits	42
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

CHD5_HUMAN
θ value	0.279714 (rank : 47)	NC score	0.135939 (rank : 66)
Query Neighborhood Hits	116	Target Neighborhood Hits	349	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

DPF1_HUMAN
θ value	0.279714 (rank : 48)	NC score	0.173140 (rank : 47)
Query Neighborhood Hits	116	Target Neighborhood Hits	136	Shared Neighborhood Hits	57
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

AF10_HUMAN
θ value	0.365318 (rank : 49)	NC score	0.259723 (rank : 19)
Query Neighborhood Hits	116	Target Neighborhood Hits	198	Shared Neighborhood Hits	39
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF10_MOUSE
θ value	0.365318 (rank : 50)	NC score	0.257291 (rank : 21)
Query Neighborhood Hits	116	Target Neighborhood Hits	182	Shared Neighborhood Hits	38
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

CHD4_HUMAN
θ value	0.365318 (rank : 51)	NC score	0.137443 (rank : 64)
Query Neighborhood Hits	116	Target Neighborhood Hits	365	Shared Neighborhood Hits	61
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	0.365318 (rank : 52)	NC score	0.133927 (rank : 69)
Query Neighborhood Hits	116	Target Neighborhood Hits	408	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

REQU_MOUSE
θ value	0.365318 (rank : 53)	NC score	0.177778 (rank : 43)
Query Neighborhood Hits	116	Target Neighborhood Hits	519	Shared Neighborhood Hits	57
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

SAPS1_HUMAN
θ value	0.365318 (rank : 54)	NC score	0.035121 (rank : 141)
Query Neighborhood Hits	116	Target Neighborhood Hits	704	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

BAZ2A_HUMAN
θ value	0.47712 (rank : 55)	NC score	0.182870 (rank : 40)
Query Neighborhood Hits	116	Target Neighborhood Hits	780	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CHD3_HUMAN
θ value	0.47712 (rank : 56)	NC score	0.131951 (rank : 70)
Query Neighborhood Hits	116	Target Neighborhood Hits	397	Shared Neighborhood Hits	66
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

ISL2_HUMAN
θ value	0.47712 (rank : 57)	NC score	0.032406 (rank : 143)
Query Neighborhood Hits	116	Target Neighborhood Hits	435	Shared Neighborhood Hits	7
SwissProt Accessions	Q96A47	Gene names	ISL2
Domain Architecture
Description	Insulin gene enhancer protein ISL-2 (Islet-2).

ISL2_MOUSE
θ value	0.47712 (rank : 58)	NC score	0.032385 (rank : 144)
Query Neighborhood Hits	116	Target Neighborhood Hits	426	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CXV0	Gene names	Isl2
Domain Architecture
Description	Insulin gene enhancer protein ISL-2 (Islet-2).

JHD3A_MOUSE
θ value	0.62314 (rank : 59)	NC score	0.158100 (rank : 54)
Query Neighborhood Hits	116	Target Neighborhood Hits	85	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

BAZ1B_HUMAN
θ value	0.813845 (rank : 60)	NC score	0.162928 (rank : 51)
Query Neighborhood Hits	116	Target Neighborhood Hits	701	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

DPF1_MOUSE
θ value	0.813845 (rank : 61)	NC score	0.174413 (rank : 46)
Query Neighborhood Hits	116	Target Neighborhood Hits	491	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

IL2RB_MOUSE
θ value	0.813845 (rank : 62)	NC score	0.046465 (rank : 135)
Query Neighborhood Hits	116	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

PHF14_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.264599 (rank : 18)
Query Neighborhood Hits	116	Target Neighborhood Hits	447	Shared Neighborhood Hits	58
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
θ value	0.813845 (rank : 64)	NC score	0.268946 (rank : 17)
Query Neighborhood Hits	116	Target Neighborhood Hits	342	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

MY18B_HUMAN
θ value	1.06291 (rank : 65)	NC score	0.010604 (rank : 168)
Query Neighborhood Hits	116	Target Neighborhood Hits	1299	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

PER3_HUMAN
θ value	1.06291 (rank : 66)	NC score	0.023789 (rank : 155)
Query Neighborhood Hits	116	Target Neighborhood Hits	479	Shared Neighborhood Hits	12
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PHF2_HUMAN
θ value	1.06291 (rank : 67)	NC score	0.106395 (rank : 91)
Query Neighborhood Hits	116	Target Neighborhood Hits	208	Shared Neighborhood Hits	28
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF2_MOUSE
θ value	1.06291 (rank : 68)	NC score	0.105676 (rank : 92)
Query Neighborhood Hits	116	Target Neighborhood Hits	241	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

ZN319_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.005951 (rank : 172)
Query Neighborhood Hits	116	Target Neighborhood Hits	772	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P2F9	Gene names	ZNF319, KIAA1388
Domain Architecture	No domain graphic available
Description	Zinc finger protein 319.

ZN319_MOUSE
θ value	1.06291 (rank : 70)	NC score	0.005985 (rank : 171)
Query Neighborhood Hits	116	Target Neighborhood Hits	762	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ERR8	Gene names	Znf319, Zfp319
Domain Architecture	No domain graphic available
Description	Zinc finger protein 319.

BAZ1B_MOUSE
θ value	1.38821 (rank : 71)	NC score	0.170100 (rank : 48)
Query Neighborhood Hits	116	Target Neighborhood Hits	394	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

JHD3A_HUMAN
θ value	1.38821 (rank : 72)	NC score	0.154123 (rank : 56)
Query Neighborhood Hits	116	Target Neighborhood Hits	78	Shared Neighborhood Hits	31
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

AIRE_MOUSE
θ value	1.81305 (rank : 73)	NC score	0.219434 (rank : 32)
Query Neighborhood Hits	116	Target Neighborhood Hits	196	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

CAC1B_HUMAN
θ value	1.81305 (rank : 74)	NC score	0.027923 (rank : 150)
Query Neighborhood Hits	116	Target Neighborhood Hits	257	Shared Neighborhood Hits	8
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

JHD3B_MOUSE
θ value	1.81305 (rank : 75)	NC score	0.155028 (rank : 55)
Query Neighborhood Hits	116	Target Neighborhood Hits	152	Shared Neighborhood Hits	29
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

PHF8_HUMAN
θ value	1.81305 (rank : 76)	NC score	0.101898 (rank : 93)
Query Neighborhood Hits	116	Target Neighborhood Hits	105	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PHF8_MOUSE
θ value	1.81305 (rank : 77)	NC score	0.100521 (rank : 94)
Query Neighborhood Hits	116	Target Neighborhood Hits	96	Shared Neighborhood Hits	25
SwissProt Accessions	Q80TJ7, Q8BLX8, Q8BLY0, Q8BZ61, Q8CG26	Gene names	Phf8, Kiaa1111
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

SC24C_HUMAN
θ value	1.81305 (rank : 78)	NC score	0.023834 (rank : 154)
Query Neighborhood Hits	116	Target Neighborhood Hits	662	Shared Neighborhood Hits	20
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

FRAS1_MOUSE
θ value	2.36792 (rank : 79)	NC score	0.014701 (rank : 161)
Query Neighborhood Hits	116	Target Neighborhood Hits	747	Shared Neighborhood Hits	17
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

PF21B_MOUSE
θ value	2.36792 (rank : 80)	NC score	0.135019 (rank : 67)
Query Neighborhood Hits	116	Target Neighborhood Hits	278	Shared Neighborhood Hits	48
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

TF2H4_MOUSE
θ value	2.36792 (rank : 81)	NC score	0.048123 (rank : 134)
Query Neighborhood Hits	116	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	O70422	Gene names	Gtf2h4
Domain Architecture
Description	TFIIH basal transcription factor complex p52 subunit (Basic transcription factor 52 kDa subunit) (BTF2-p52) (General transcription factor IIH polypeptide 4).

CS007_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.024453 (rank : 152)
Query Neighborhood Hits	116	Target Neighborhood Hits	464	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

ISL1_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.028934 (rank : 146)
Query Neighborhood Hits	116	Target Neighborhood Hits	421	Shared Neighborhood Hits	10
SwissProt Accessions	P61371, P20663, P47894	Gene names	ISL1
Domain Architecture
Description	Insulin gene enhancer protein ISL-1 (Islet-1).

ISL1_MOUSE
θ value	3.0926 (rank : 84)	NC score	0.028934 (rank : 147)
Query Neighborhood Hits	116	Target Neighborhood Hits	421	Shared Neighborhood Hits	10
SwissProt Accessions	P61372, P20663, P47894, Q812D8	Gene names	Isl1
Domain Architecture
Description	Insulin gene enhancer protein ISL-1 (Islet-1).

JAD1D_HUMAN
θ value	3.0926 (rank : 85)	NC score	0.128109 (rank : 72)
Query Neighborhood Hits	116	Target Neighborhood Hits	147	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JHD3B_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.158665 (rank : 53)
Query Neighborhood Hits	116	Target Neighborhood Hits	128	Shared Neighborhood Hits	31
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

NFX1_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.036517 (rank : 137)
Query Neighborhood Hits	116	Target Neighborhood Hits	405	Shared Neighborhood Hits	21
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

TF2H4_HUMAN
θ value	3.0926 (rank : 88)	NC score	0.045559 (rank : 136)
Query Neighborhood Hits	116	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q92759	Gene names	GTF2H4
Domain Architecture
Description	TFIIH basal transcription factor complex p52 subunit (Basic transcription factor 52 kDa subunit) (BTF2-p52) (General transcription factor IIH polypeptide 4).

ZMY11_MOUSE
θ value	3.0926 (rank : 89)	NC score	0.107877 (rank : 88)
Query Neighborhood Hits	116	Target Neighborhood Hits	198	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

BAZ1A_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.164871 (rank : 50)
Query Neighborhood Hits	116	Target Neighborhood Hits	693	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CN130_MOUSE
θ value	4.03905 (rank : 91)	NC score	0.088475 (rank : 97)
Query Neighborhood Hits	116	Target Neighborhood Hits	39	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BU04, Q80UT9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130 homolog.

DIDO1_HUMAN
θ value	4.03905 (rank : 92)	NC score	0.067452 (rank : 106)
Query Neighborhood Hits	116	Target Neighborhood Hits	960	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

NUMBL_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.018829 (rank : 158)
Query Neighborhood Hits	116	Target Neighborhood Hits	394	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

RUNX3_MOUSE
θ value	4.03905 (rank : 94)	NC score	0.033303 (rank : 142)
Query Neighborhood Hits	116	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

SCNNB_MOUSE
θ value	4.03905 (rank : 95)	NC score	0.014099 (rank : 162)
Query Neighborhood Hits	116	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WU38	Gene names	Scnn1b
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit beta (Epithelial Na+ channel subunit beta) (Beta ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) (Beta NaCH).

TR19L_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.029631 (rank : 145)
Query Neighborhood Hits	116	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

ASH2L_HUMAN
θ value	5.27518 (rank : 97)	NC score	0.035220 (rank : 140)
Query Neighborhood Hits	116	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UBL3, O60659, O60660, Q96B62	Gene names	ASH2L
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

ASH2L_MOUSE
θ value	5.27518 (rank : 98)	NC score	0.035479 (rank : 139)
Query Neighborhood Hits	116	Target Neighborhood Hits	40	Shared Neighborhood Hits	6
SwissProt Accessions	Q91X20, Q3UIF9, Q9Z2X4	Gene names	Ash2l
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

EVI2A_MOUSE
θ value	5.27518 (rank : 99)	NC score	0.021708 (rank : 156)
Query Neighborhood Hits	116	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	P20934	Gene names	Evi2a, Evi-2, Evi-2a, Evi2
Domain Architecture
Description	EVI2A protein precursor (Ecotropic viral integration site 2A protein).

PAK4_MOUSE
θ value	5.27518 (rank : 100)	NC score	0.000766 (rank : 173)
Query Neighborhood Hits	116	Target Neighborhood Hits	1098	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

T22D4_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.020925 (rank : 157)
Query Neighborhood Hits	116	Target Neighborhood Hits	403	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TPSN_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.016481 (rank : 159)
Query Neighborhood Hits	116	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	O15533, O15210, O15272, Q5STJ8, Q5STK6, Q5STQ5, Q5STQ6, Q66K65, Q96KK7, Q9HAN8, Q9UEE0, Q9UEE4, Q9UIZ6, Q9Y6K2	Gene names	TAPBP, NGS17, TAPA
Domain Architecture
Description	Tapasin precursor (TPSN) (TPN) (TAP-binding protein) (TAP-associated protein) (NGS-17).

TRI35_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.010975 (rank : 166)
Query Neighborhood Hits	116	Target Neighborhood Hits	382	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

BSN_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.028383 (rank : 148)
Query Neighborhood Hits	116	Target Neighborhood Hits	1537	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CN130_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.084028 (rank : 98)
Query Neighborhood Hits	116	Target Neighborhood Hits	44	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N806, Q86U21, Q86UA9, Q96BY0, Q9NVV6	Gene names	C14orf130
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130.

DOT1L_HUMAN
θ value	6.88961 (rank : 106)	NC score	0.028326 (rank : 149)
Query Neighborhood Hits	116	Target Neighborhood Hits	660	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

SYGP1_HUMAN
θ value	6.88961 (rank : 107)	NC score	0.009706 (rank : 169)
Query Neighborhood Hits	116	Target Neighborhood Hits	589	Shared Neighborhood Hits	14
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

ZN420_HUMAN
θ value	6.88961 (rank : 108)	NC score	-0.000762 (rank : 174)
Query Neighborhood Hits	116	Target Neighborhood Hits	759	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TAQ5	Gene names	ZNF420
Domain Architecture	No domain graphic available
Description	Zinc finger protein 420.

GON4L_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.011153 (rank : 164)
Query Neighborhood Hits	116	Target Neighborhood Hits	455	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

GR65_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.010916 (rank : 167)
Query Neighborhood Hits	116	Target Neighborhood Hits	148	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

MS3L1_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.011070 (rank : 165)
Query Neighborhood Hits	116	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N5Y2, Q9UG70, Q9Y5Z8	Gene names	MSL3L1
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

SCNNB_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.011494 (rank : 163)
Query Neighborhood Hits	116	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P51168, O60891, Q96KG2, Q9UJ32, Q9UMU5	Gene names	SCNN1B
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit beta (Epithelial Na+ channel subunit beta) (Beta ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) (Beta NaCH) (ENaCB).

TRIM8_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.025115 (rank : 151)
Query Neighborhood Hits	116	Target Neighborhood Hits	650	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.024243 (rank : 153)
Query Neighborhood Hits	116	Target Neighborhood Hits	674	Shared Neighborhood Hits	20
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TSSC4_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.015515 (rank : 160)
Query Neighborhood Hits	116	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5U2, Q86VL2, Q9BRS6	Gene names	TSSC4
Domain Architecture	No domain graphic available
Description	Protein TSSC4 (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein) (Tumor-suppressing STF cDNA 4 protein).

ZDHC8_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.006780 (rank : 170)
Query Neighborhood Hits	116	Target Neighborhood Hits	243	Shared Neighborhood Hits	9
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.151609 (rank : 57)
Query Neighborhood Hits	116	Target Neighborhood Hits	803	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BPTF_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.160145 (rank : 52)
Query Neighborhood Hits	116	Target Neighborhood Hits	786	Shared Neighborhood Hits	69
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRD2_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.057865 (rank : 115)
Query Neighborhood Hits	116	Target Neighborhood Hits	242	Shared Neighborhood Hits	23
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRD3_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.051459 (rank : 130)
Query Neighborhood Hits	116	Target Neighborhood Hits	369	Shared Neighborhood Hits	20
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.051646 (rank : 129)
Query Neighborhood Hits	116	Target Neighborhood Hits	402	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRD4_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.050937 (rank : 132)
Query Neighborhood Hits	116	Target Neighborhood Hits	851	Shared Neighborhood Hits	29
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.054222 (rank : 123)
Query Neighborhood Hits	116	Target Neighborhood Hits	845	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRD7_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.058512 (rank : 113)
Query Neighborhood Hits	116	Target Neighborhood Hits	94	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD7_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.056124 (rank : 119)
Query Neighborhood Hits	116	Target Neighborhood Hits	141	Shared Neighborhood Hits	15
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BRD8_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.051660 (rank : 128)
Query Neighborhood Hits	116	Target Neighborhood Hits	292	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRD9_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.057177 (rank : 117)
Query Neighborhood Hits	116	Target Neighborhood Hits	56	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

BRD9_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.058395 (rank : 114)
Query Neighborhood Hits	116	Target Neighborhood Hits	84	Shared Neighborhood Hits	15
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

CBP_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.052118 (rank : 126)
Query Neighborhood Hits	116	Target Neighborhood Hits	941	Shared Neighborhood Hits	38
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CECR2_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.062742 (rank : 109)
Query Neighborhood Hits	116	Target Neighborhood Hits	543	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

EP300_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.051031 (rank : 131)
Query Neighborhood Hits	116	Target Neighborhood Hits	821	Shared Neighborhood Hits	35
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GCNL2_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.057629 (rank : 116)
Query Neighborhood Hits	116	Target Neighborhood Hits	159	Shared Neighborhood Hits	15
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

GCNL2_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.055780 (rank : 120)
Query Neighborhood Hits	116	Target Neighborhood Hits	146	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

JAD1C_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.109739 (rank : 85)
Query Neighborhood Hits	116	Target Neighborhood Hits	187	Shared Neighborhood Hits	62
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.110002 (rank : 83)
Query Neighborhood Hits	116	Target Neighborhood Hits	164	Shared Neighborhood Hits	62
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1D_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.110636 (rank : 82)
Query Neighborhood Hits	116	Target Neighborhood Hits	228	Shared Neighborhood Hits	65
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JHD1B_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.050018 (rank : 133)
Query Neighborhood Hits	116	Target Neighborhood Hits	214	Shared Neighborhood Hits	22
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

JHD3C_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.137359 (rank : 65)
Query Neighborhood Hits	116	Target Neighborhood Hits	91	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

JHD3C_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.139076 (rank : 63)
Query Neighborhood Hits	116	Target Neighborhood Hits	84	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

K1333_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.060486 (rank : 110)
Query Neighborhood Hits	116	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

MYST3_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.111894 (rank : 80)
Query Neighborhood Hits	116	Target Neighborhood Hits	772	Shared Neighborhood Hits	63
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.109878 (rank : 84)
Query Neighborhood Hits	116	Target Neighborhood Hits	688	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

MYST4_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.109695 (rank : 86)
Query Neighborhood Hits	116	Target Neighborhood Hits	671	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.114050 (rank : 78)
Query Neighborhood Hits	116	Target Neighborhood Hits	416	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

NSD1_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.119588 (rank : 76)
Query Neighborhood Hits	116	Target Neighborhood Hits	427	Shared Neighborhood Hits	57
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.119777 (rank : 75)
Query Neighborhood Hits	116	Target Neighborhood Hits	472	Shared Neighborhood Hits	61
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PB1_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.052863 (rank : 124)
Query Neighborhood Hits	116	Target Neighborhood Hits	261	Shared Neighborhood Hits	20
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PCAF_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.056790 (rank : 118)
Query Neighborhood Hits	116	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

PF21B_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.122909 (rank : 74)
Query Neighborhood Hits	116	Target Neighborhood Hits	197	Shared Neighborhood Hits	42
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF10_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.183879 (rank : 39)
Query Neighborhood Hits	116	Target Neighborhood Hits	151	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.181352 (rank : 41)
Query Neighborhood Hits	116	Target Neighborhood Hits	131	Shared Neighborhood Hits	49
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF11_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.083451 (rank : 99)
Query Neighborhood Hits	116	Target Neighborhood Hits	42	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PHF12_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.148089 (rank : 60)
Query Neighborhood Hits	116	Target Neighborhood Hits	174	Shared Neighborhood Hits	55
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.150627 (rank : 58)
Query Neighborhood Hits	116	Target Neighborhood Hits	172	Shared Neighborhood Hits	52
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF20_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.051997 (rank : 127)
Query Neighborhood Hits	116	Target Neighborhood Hits	513	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PHF6_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.073699 (rank : 102)
Query Neighborhood Hits	116	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF6_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.067490 (rank : 105)
Query Neighborhood Hits	116	Target Neighborhood Hits	39	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PHF7_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.069250 (rank : 104)
Query Neighborhood Hits	116	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF7_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.088663 (rank : 96)
Query Neighborhood Hits	116	Target Neighborhood Hits	65	Shared Neighborhood Hits	28
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PKCB1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.123077 (rank : 73)
Query Neighborhood Hits	116	Target Neighborhood Hits	488	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

RAI1_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.071367 (rank : 103)
Query Neighborhood Hits	116	Target Neighborhood Hits	360	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RAI1_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.066159 (rank : 107)
Query Neighborhood Hits	116	Target Neighborhood Hits	344	Shared Neighborhood Hits	27
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RSF1_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.134958 (rank : 68)
Query Neighborhood Hits	116	Target Neighborhood Hits	539	Shared Neighborhood Hits	53
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SET1A_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.055728 (rank : 121)
Query Neighborhood Hits	116	Target Neighborhood Hits	690	Shared Neighborhood Hits	18
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TAF1_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.052503 (rank : 125)
Query Neighborhood Hits	116	Target Neighborhood Hits	136	Shared Neighborhood Hits	16
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

TAF3_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.075687 (rank : 101)
Query Neighborhood Hits	116	Target Neighborhood Hits	568	Shared Neighborhood Hits	52
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.079131 (rank : 100)
Query Neighborhood Hits	116	Target Neighborhood Hits	463	Shared Neighborhood Hits	49
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TRI45_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.059003 (rank : 111)
Query Neighborhood Hits	116	Target Neighborhood Hits	155	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.058656 (rank : 112)
Query Neighborhood Hits	116	Target Neighborhood Hits	155	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

UHRF1_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.107440 (rank : 90)
Query Neighborhood Hits	116	Target Neighborhood Hits	272	Shared Neighborhood Hits	52
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.109298 (rank : 87)
Query Neighborhood Hits	116	Target Neighborhood Hits	278	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.107476 (rank : 89)
Query Neighborhood Hits	116	Target Neighborhood Hits	269	Shared Neighborhood Hits	53
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.114454 (rank : 77)
Query Neighborhood Hits	116	Target Neighborhood Hits	275	Shared Neighborhood Hits	53
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ZMY11_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.089311 (rank : 95)
Query Neighborhood Hits	116	Target Neighborhood Hits	201	Shared Neighborhood Hits	40
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

Hits sorted by NC score

PHF1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	116	Target Neighborhood Hits	116	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

PHF1_HUMAN
NC score	0.991078 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	116	Target Neighborhood Hits	117	Shared Neighborhood Hits	95
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

MTF2_HUMAN
NC score	0.920378 (rank : 3)	θ value	2.00813e-108 (rank : 3)
Query Neighborhood Hits	116	Target Neighborhood Hits	119	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
NC score	0.918630 (rank : 4)	θ value	2.6227e-108 (rank : 4)
Query Neighborhood Hits	116	Target Neighborhood Hits	126	Shared Neighborhood Hits	71
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

PHF22_MOUSE
NC score	0.418163 (rank : 5)	θ value	1.99992e-07 (rank : 5)
Query Neighborhood Hits	116	Target Neighborhood Hits	89	Shared Neighborhood Hits	35
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

JADE3_HUMAN
NC score	0.392168 (rank : 6)	θ value	3.41135e-07 (rank : 6)
Query Neighborhood Hits	116	Target Neighborhood Hits	148	Shared Neighborhood Hits	59
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE3_MOUSE
NC score	0.389031 (rank : 7)	θ value	7.59969e-07 (rank : 9)
Query Neighborhood Hits	116	Target Neighborhood Hits	174	Shared Neighborhood Hits	59
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

JADE2_HUMAN
NC score	0.385496 (rank : 8)	θ value	7.59969e-07 (rank : 7)
Query Neighborhood Hits	116	Target Neighborhood Hits	199	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

PHF22_HUMAN
NC score	0.378665 (rank : 9)	θ value	2.21117e-06 (rank : 10)
Query Neighborhood Hits	116	Target Neighborhood Hits	121	Shared Neighborhood Hits	35
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

JADE1_HUMAN
NC score	0.377650 (rank : 10)	θ value	8.40245e-06 (rank : 13)
Query Neighborhood Hits	116	Target Neighborhood Hits	140	Shared Neighborhood Hits	56
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
NC score	0.377015 (rank : 11)	θ value	8.40245e-06 (rank : 14)
Query Neighborhood Hits	116	Target Neighborhood Hits	160	Shared Neighborhood Hits	56
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE2_MOUSE
NC score	0.366871 (rank : 12)	θ value	7.59969e-07 (rank : 8)
Query Neighborhood Hits	116	Target Neighborhood Hits	560	Shared Neighborhood Hits	66
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

BRPF1_HUMAN
NC score	0.340154 (rank : 13)	θ value	2.88788e-06 (rank : 11)
Query Neighborhood Hits	116	Target Neighborhood Hits	259	Shared Neighborhood Hits	60
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

CSR2B_HUMAN
NC score	0.338312 (rank : 14)	θ value	3.19293e-05 (rank : 16)
Query Neighborhood Hits	116	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H8E8, Q96GW6, Q96IH3, Q9HBF0, Q9UIY5	Gene names	CSRP2BP
Domain Architecture
Description	Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (CRP2BP) (CRP2-binding partner).

BRD1_HUMAN
NC score	0.325751 (rank : 15)	θ value	5.44631e-05 (rank : 17)
Query Neighborhood Hits	116	Target Neighborhood Hits	188	Shared Neighborhood Hits	58
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF3_HUMAN
NC score	0.309206 (rank : 16)	θ value	0.00035302 (rank : 18)
Query Neighborhood Hits	116	Target Neighborhood Hits	217	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

PHF14_MOUSE
NC score	0.268946 (rank : 17)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	116	Target Neighborhood Hits	342	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PHF14_HUMAN
NC score	0.264599 (rank : 18)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	116	Target Neighborhood Hits	447	Shared Neighborhood Hits	58
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

AF10_HUMAN
NC score	0.259723 (rank : 19)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	116	Target Neighborhood Hits	198	Shared Neighborhood Hits	39
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF17_HUMAN
NC score	0.257587 (rank : 20)	θ value	0.279714 (rank : 46)
Query Neighborhood Hits	116	Target Neighborhood Hits	230	Shared Neighborhood Hits	42
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

AF10_MOUSE
NC score	0.257291 (rank : 21)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	116	Target Neighborhood Hits	182	Shared Neighborhood Hits	38
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

HRX_HUMAN
NC score	0.252079 (rank : 22)	θ value	6.43352e-06 (rank : 12)
Query Neighborhood Hits	116	Target Neighborhood Hits	825	Shared Neighborhood Hits	68
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

AIRE_HUMAN
NC score	0.249918 (rank : 23)	θ value	0.0252991 (rank : 29)
Query Neighborhood Hits	116	Target Neighborhood Hits	144	Shared Neighborhood Hits	56
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

MLL4_HUMAN
NC score	0.249516 (rank : 24)	θ value	1.09739e-05 (rank : 15)
Query Neighborhood Hits	116	Target Neighborhood Hits	722	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

TRI66_MOUSE
NC score	0.241525 (rank : 25)	θ value	0.000786445 (rank : 19)
Query Neighborhood Hits	116	Target Neighborhood Hits	491	Shared Neighborhood Hits	58
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TIF1B_MOUSE
NC score	0.238301 (rank : 26)	θ value	0.00665767 (rank : 25)
Query Neighborhood Hits	116	Target Neighborhood Hits	276	Shared Neighborhood Hits	55
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TIF1B_HUMAN
NC score	0.235720 (rank : 27)	θ value	0.00509761 (rank : 24)
Query Neighborhood Hits	116	Target Neighborhood Hits	312	Shared Neighborhood Hits	55
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TRI66_HUMAN
NC score	0.227869 (rank : 28)	θ value	0.00665767 (rank : 26)
Query Neighborhood Hits	116	Target Neighborhood Hits	479	Shared Neighborhood Hits	56
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TIF1A_MOUSE
NC score	0.225817 (rank : 29)	θ value	0.00509761 (rank : 23)
Query Neighborhood Hits	116	Target Neighborhood Hits	307	Shared Neighborhood Hits	58
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1A_HUMAN
NC score	0.222814 (rank : 30)	θ value	0.00390308 (rank : 22)
Query Neighborhood Hits	116	Target Neighborhood Hits	327	Shared Neighborhood Hits	57
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

LY10_HUMAN
NC score	0.222788 (rank : 31)	θ value	0.00298849 (rank : 21)
Query Neighborhood Hits	116	Target Neighborhood Hits	151	Shared Neighborhood Hits	47
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

AIRE_MOUSE
NC score	0.219434 (rank : 32)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	116	Target Neighborhood Hits	196	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

PF21A_MOUSE
NC score	0.219096 (rank : 33)	θ value	0.0736092 (rank : 33)
Query Neighborhood Hits	116	Target Neighborhood Hits	285	Shared Neighborhood Hits	59
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21A_HUMAN
NC score	0.215171 (rank : 34)	θ value	0.0961366 (rank : 35)
Query Neighborhood Hits	116	Target Neighborhood Hits	303	Shared Neighborhood Hits	59
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

TIF1G_MOUSE
NC score	0.207945 (rank : 35)	θ value	0.0148317 (rank : 28)
Query Neighborhood Hits	116	Target Neighborhood Hits	498	Shared Neighborhood Hits	60
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIF1G_HUMAN
NC score	0.207632 (rank : 36)	θ value	0.0148317 (rank : 27)
Query Neighborhood Hits	116	Target Neighborhood Hits	410	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

REQU_HUMAN
NC score	0.184291 (rank : 37)	θ value	0.21417 (rank : 45)
Query Neighborhood Hits	116	Target Neighborhood Hits	523	Shared Neighborhood Hits	58
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

BAZ2A_MOUSE
NC score	0.184042 (rank : 38)	θ value	0.163984 (rank : 41)
Query Neighborhood Hits	116	Target Neighborhood Hits	744	Shared Neighborhood Hits	62
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

PHF10_HUMAN
NC score	0.183879 (rank : 39)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	116	Target Neighborhood Hits	151	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

BAZ2A_HUMAN
NC score	0.182870 (rank : 40)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	116	Target Neighborhood Hits	780	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

PHF10_MOUSE
NC score	0.181352 (rank : 41)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	116	Target Neighborhood Hits	131	Shared Neighborhood Hits	49
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

SP110_HUMAN
NC score	0.180998 (rank : 42)	θ value	0.0431538 (rank : 31)
Query Neighborhood Hits	116	Target Neighborhood Hits	141	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

REQU_MOUSE
NC score	0.177778 (rank : 43)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	116	Target Neighborhood Hits	519	Shared Neighborhood Hits	57
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

MLL2_HUMAN
NC score	0.177030 (rank : 44)	θ value	0.0330416 (rank : 30)
Query Neighborhood Hits	116	Target Neighborhood Hits	1788	Shared Neighborhood Hits	90
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_MOUSE
NC score	0.175889 (rank : 45)	θ value	0.125558 (rank : 40)
Query Neighborhood Hits	116	Target Neighborhood Hits	1399	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

DPF1_MOUSE
NC score	0.174413 (rank : 46)	θ value	0.813845 (rank : 61)
Query Neighborhood Hits	116	Target Neighborhood Hits	491	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

DPF1_HUMAN
NC score	0.173140 (rank : 47)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	116	Target Neighborhood Hits	136	Shared Neighborhood Hits	57
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

BAZ1B_MOUSE
NC score	0.170100 (rank : 48)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	116	Target Neighborhood Hits	394	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

MLL3_HUMAN
NC score	0.167381 (rank : 49)	θ value	0.125558 (rank : 39)
Query Neighborhood Hits	116	Target Neighborhood Hits	1644	Shared Neighborhood Hits	83
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

BAZ1A_HUMAN
NC score	0.164871 (rank : 50)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	116	Target Neighborhood Hits	693	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
NC score	0.162928 (rank : 51)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	116	Target Neighborhood Hits	701	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BPTF_HUMAN
NC score	0.160145 (rank : 52)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	116	Target Neighborhood Hits	786	Shared Neighborhood Hits	69
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

JHD3B_HUMAN
NC score	0.158665 (rank : 53)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	116	Target Neighborhood Hits	128	Shared Neighborhood Hits	31
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3A_MOUSE
NC score	0.158100 (rank : 54)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	116	Target Neighborhood Hits	85	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3B_MOUSE
NC score	0.155028 (rank : 55)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	116	Target Neighborhood Hits	152	Shared Neighborhood Hits	29
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3A_HUMAN
NC score	0.154123 (rank : 56)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	116	Target Neighborhood Hits	78	Shared Neighborhood Hits	31
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

BAZ2B_HUMAN
NC score	0.151609 (rank : 57)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	116	Target Neighborhood Hits	803	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

PHF12_MOUSE
NC score	0.150627 (rank : 58)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	116	Target Neighborhood Hits	172	Shared Neighborhood Hits	52
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

CXCC1_HUMAN
NC score	0.150373 (rank : 59)	θ value	0.0961366 (rank : 34)
Query Neighborhood Hits	116	Target Neighborhood Hits	143	Shared Neighborhood Hits	36
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

PHF12_HUMAN
NC score	0.148089 (rank : 60)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	116	Target Neighborhood Hits	174	Shared Neighborhood Hits	55
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

CXCC1_MOUSE
NC score	0.147706 (rank : 61)	θ value	0.125558 (rank : 37)
Query Neighborhood Hits	116	Target Neighborhood Hits	124	Shared Neighborhood Hits	35
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

JAD1A_HUMAN
NC score	0.142357 (rank : 62)	θ value	0.163984 (rank : 42)
Query Neighborhood Hits	116	Target Neighborhood Hits	328	Shared Neighborhood Hits	68
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

JHD3C_MOUSE
NC score	0.139076 (rank : 63)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	116	Target Neighborhood Hits	84	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

CHD4_HUMAN
NC score	0.137443 (rank : 64)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	116	Target Neighborhood Hits	365	Shared Neighborhood Hits	61
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

JHD3C_HUMAN
NC score	0.137359 (rank : 65)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	116	Target Neighborhood Hits	91	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

CHD5_HUMAN
NC score	0.135939 (rank : 66)	θ value	0.279714 (rank : 47)
Query Neighborhood Hits	116	Target Neighborhood Hits	349	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

PF21B_MOUSE
NC score	0.135019 (rank : 67)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	116	Target Neighborhood Hits	278	Shared Neighborhood Hits	48
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

RSF1_HUMAN
NC score	0.134958 (rank : 68)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	116	Target Neighborhood Hits	539	Shared Neighborhood Hits	53
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

CHD4_MOUSE
NC score	0.133927 (rank : 69)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	116	Target Neighborhood Hits	408	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD3_HUMAN
NC score	0.131951 (rank : 70)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	116	Target Neighborhood Hits	397	Shared Neighborhood Hits	66
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

TCF19_HUMAN
NC score	0.129754 (rank : 71)	θ value	0.163984 (rank : 43)
Query Neighborhood Hits	116	Target Neighborhood Hits	124	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

JAD1D_HUMAN
NC score	0.128109 (rank : 72)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	116	Target Neighborhood Hits	147	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

PKCB1_HUMAN
NC score	0.123077 (rank : 73)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	116	Target Neighborhood Hits	488	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PF21B_HUMAN
NC score	0.122909 (rank : 74)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	116	Target Neighborhood Hits	197	Shared Neighborhood Hits	42
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

NSD1_MOUSE
NC score	0.119777 (rank : 75)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	116	Target Neighborhood Hits	472	Shared Neighborhood Hits	61
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

NSD1_HUMAN
NC score	0.119588 (rank : 76)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	116	Target Neighborhood Hits	427	Shared Neighborhood Hits	57
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

UHRF2_MOUSE
NC score	0.114454 (rank : 77)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	116	Target Neighborhood Hits	275	Shared Neighborhood Hits	53
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

MYST4_MOUSE
NC score	0.114050 (rank : 78)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	116	Target Neighborhood Hits	416	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

K1718_HUMAN
NC score	0.113478 (rank : 79)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	116	Target Neighborhood Hits	114	Shared Neighborhood Hits	21
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

MYST3_HUMAN
NC score	0.111894 (rank : 80)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	116	Target Neighborhood Hits	772	Shared Neighborhood Hits	63
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

K1718_MOUSE
NC score	0.111720 (rank : 81)	θ value	0.21417 (rank : 44)
Query Neighborhood Hits	116	Target Neighborhood Hits	98	Shared Neighborhood Hits	21
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

JAD1D_MOUSE
NC score	0.110636 (rank : 82)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	116	Target Neighborhood Hits	228	Shared Neighborhood Hits	65
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1C_MOUSE
NC score	0.110002 (rank : 83)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	116	Target Neighborhood Hits	164	Shared Neighborhood Hits	62
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

MYST3_MOUSE
NC score	0.109878 (rank : 84)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	116	Target Neighborhood Hits	688	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

JAD1C_HUMAN
NC score	0.109739 (rank : 85)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	116	Target Neighborhood Hits	187	Shared Neighborhood Hits	62
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

MYST4_HUMAN
NC score	0.109695 (rank : 86)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	116	Target Neighborhood Hits	671	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

UHRF1_MOUSE
NC score	0.109298 (rank : 87)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	116	Target Neighborhood Hits	278	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

ZMY11_MOUSE
NC score	0.107877 (rank : 88)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	116	Target Neighborhood Hits	198	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

UHRF2_HUMAN
NC score	0.107476 (rank : 89)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	116	Target Neighborhood Hits	269	Shared Neighborhood Hits	53
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF1_HUMAN
NC score	0.107440 (rank : 90)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	116	Target Neighborhood Hits	272	Shared Neighborhood Hits	52
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

PHF2_HUMAN
NC score	0.106395 (rank : 91)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	116	Target Neighborhood Hits	208	Shared Neighborhood Hits	28
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF2_MOUSE
NC score	0.105676 (rank : 92)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	116	Target Neighborhood Hits	241	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF8_HUMAN
NC score	0.101898 (rank : 93)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	116	Target Neighborhood Hits	105	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PHF8_MOUSE
NC score	0.100521 (rank : 94)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	116	Target Neighborhood Hits	96	Shared Neighborhood Hits	25
SwissProt Accessions	Q80TJ7, Q8BLX8, Q8BLY0, Q8BZ61, Q8CG26	Gene names	Phf8, Kiaa1111
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

ZMY11_HUMAN
NC score	0.089311 (rank : 95)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	116	Target Neighborhood Hits	201	Shared Neighborhood Hits	40
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

PHF7_MOUSE
NC score	0.088663 (rank : 96)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	116	Target Neighborhood Hits	65	Shared Neighborhood Hits	28
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

CN130_MOUSE
NC score	0.088475 (rank : 97)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	116	Target Neighborhood Hits	39	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BU04, Q80UT9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130 homolog.

CN130_HUMAN
NC score	0.084028 (rank : 98)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	116	Target Neighborhood Hits	44	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N806, Q86U21, Q86UA9, Q96BY0, Q9NVV6	Gene names	C14orf130
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130.

PHF11_HUMAN
NC score	0.083451 (rank : 99)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	116	Target Neighborhood Hits	42	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

TAF3_MOUSE
NC score	0.079131 (rank : 100)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	116	Target Neighborhood Hits	463	Shared Neighborhood Hits	49
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_HUMAN
NC score	0.075687 (rank : 101)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	116	Target Neighborhood Hits	568	Shared Neighborhood Hits	52
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

PHF6_HUMAN
NC score	0.073699 (rank : 102)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	116	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

RAI1_HUMAN
NC score	0.071367 (rank : 103)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	116	Target Neighborhood Hits	360	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

PHF7_HUMAN
NC score	0.069250 (rank : 104)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	116	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF6_MOUSE
NC score	0.067490 (rank : 105)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	116	Target Neighborhood Hits	39	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

DIDO1_HUMAN
NC score	0.067452 (rank : 106)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	116	Target Neighborhood Hits	960	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

RAI1_MOUSE
NC score	0.066159 (rank : 107)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	116	Target Neighborhood Hits	344	Shared Neighborhood Hits	27
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

PARM1_MOUSE
NC score	0.063703 (rank : 108)	θ value	0.0736092 (rank : 32)
Query Neighborhood Hits	116	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

CECR2_HUMAN
NC score	0.062742 (rank : 109)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	116	Target Neighborhood Hits	543	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

K1333_MOUSE
NC score	0.060486 (rank : 110)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	116	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

TRI45_HUMAN
NC score	0.059003 (rank : 111)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	116	Target Neighborhood Hits	155	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
NC score	0.058656 (rank : 112)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	116	Target Neighborhood Hits	155	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

BRD7_HUMAN
NC score	0.058512 (rank : 113)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	116	Target Neighborhood Hits	94	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD9_MOUSE
NC score	0.058395 (rank : 114)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	116	Target Neighborhood Hits	84	Shared Neighborhood Hits	15
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

BRD2_HUMAN
NC score	0.057865 (rank : 115)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	116	Target Neighborhood Hits	242	Shared Neighborhood Hits	23
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

GCNL2_HUMAN
NC score	0.057629 (rank : 116)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	116	Target Neighborhood Hits	159	Shared Neighborhood Hits	15
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

BRD9_HUMAN
NC score	0.057177 (rank : 117)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	116	Target Neighborhood Hits	56	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

PCAF_HUMAN
NC score	0.056790 (rank : 118)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	116	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

BRD7_MOUSE
NC score	0.056124 (rank : 119)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	116	Target Neighborhood Hits	141	Shared Neighborhood Hits	15
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

GCNL2_MOUSE
NC score	0.055780 (rank : 120)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	116	Target Neighborhood Hits	146	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

SET1A_HUMAN
NC score	0.055728 (rank : 121)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	116	Target Neighborhood Hits	690	Shared Neighborhood Hits	18
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

RUNX3_HUMAN
NC score	0.054459 (rank : 122)	θ value	0.0961366 (rank : 36)
Query Neighborhood Hits	116	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

BRD4_MOUSE
NC score	0.054222 (rank : 123)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	116	Target Neighborhood Hits	845	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

PB1_HUMAN
NC score	0.052863 (rank : 124)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	116	Target Neighborhood Hits	261	Shared Neighborhood Hits	20
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

TAF1_HUMAN
NC score	0.052503 (rank : 125)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	116	Target Neighborhood Hits	136	Shared Neighborhood Hits	16
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

CBP_HUMAN
NC score	0.052118 (rank : 126)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	116	Target Neighborhood Hits	941	Shared Neighborhood Hits	38
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PHF20_MOUSE
NC score	0.051997 (rank : 127)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	116	Target Neighborhood Hits	513	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

BRD8_HUMAN
NC score	0.051660 (rank : 128)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	116	Target Neighborhood Hits	292	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRD3_MOUSE
NC score	0.051646 (rank : 129)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	116	Target Neighborhood Hits	402	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRD3_HUMAN
NC score	0.051459 (rank : 130)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	116	Target Neighborhood Hits	369	Shared Neighborhood Hits	20
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

EP300_HUMAN
NC score	0.051031 (rank : 131)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	116	Target Neighborhood Hits	821	Shared Neighborhood Hits	35
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

BRD4_HUMAN
NC score	0.050937 (rank : 132)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	116	Target Neighborhood Hits	851	Shared Neighborhood Hits	29
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

JHD1B_MOUSE
NC score	0.050018 (rank : 133)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	116	Target Neighborhood Hits	214	Shared Neighborhood Hits	22
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

TF2H4_MOUSE
NC score	0.048123 (rank : 134)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	116	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	O70422	Gene names	Gtf2h4
Domain Architecture
Description	TFIIH basal transcription factor complex p52 subunit (Basic transcription factor 52 kDa subunit) (BTF2-p52) (General transcription factor IIH polypeptide 4).

IL2RB_MOUSE
NC score	0.046465 (rank : 135)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	116	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

TF2H4_HUMAN
NC score	0.045559 (rank : 136)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	116	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q92759	Gene names	GTF2H4
Domain Architecture
Description	TFIIH basal transcription factor complex p52 subunit (Basic transcription factor 52 kDa subunit) (BTF2-p52) (General transcription factor IIH polypeptide 4).

NFX1_HUMAN
NC score	0.036517 (rank : 137)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	116	Target Neighborhood Hits	405	Shared Neighborhood Hits	21
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

CAC1B_MOUSE
NC score	0.036114 (rank : 138)	θ value	0.00134147 (rank : 20)
Query Neighborhood Hits	116	Target Neighborhood Hits	351	Shared Neighborhood Hits	7
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

ASH2L_MOUSE
NC score	0.035479 (rank : 139)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	116	Target Neighborhood Hits	40	Shared Neighborhood Hits	6
SwissProt Accessions	Q91X20, Q3UIF9, Q9Z2X4	Gene names	Ash2l
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

ASH2L_HUMAN
NC score	0.035220 (rank : 140)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	116	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UBL3, O60659, O60660, Q96B62	Gene names	ASH2L
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

SAPS1_HUMAN
NC score	0.035121 (rank : 141)	θ value	0.365318 (rank : 54)
Query Neighborhood Hits	116	Target Neighborhood Hits	704	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

RUNX3_MOUSE
NC score	0.033303 (rank : 142)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	116	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

ISL2_HUMAN
NC score	0.032406 (rank : 143)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	116	Target Neighborhood Hits	435	Shared Neighborhood Hits	7
SwissProt Accessions	Q96A47	Gene names	ISL2
Domain Architecture
Description	Insulin gene enhancer protein ISL-2 (Islet-2).

ISL2_MOUSE
NC score	0.032385 (rank : 144)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	116	Target Neighborhood Hits	426	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CXV0	Gene names	Isl2
Domain Architecture
Description	Insulin gene enhancer protein ISL-2 (Islet-2).

TR19L_HUMAN
NC score	0.029631 (rank : 145)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	116	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

ISL1_HUMAN
NC score	0.028934 (rank : 146)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	116	Target Neighborhood Hits	421	Shared Neighborhood Hits	10
SwissProt Accessions	P61371, P20663, P47894	Gene names	ISL1
Domain Architecture
Description	Insulin gene enhancer protein ISL-1 (Islet-1).

ISL1_MOUSE
NC score	0.028934 (rank : 147)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	116	Target Neighborhood Hits	421	Shared Neighborhood Hits	10
SwissProt Accessions	P61372, P20663, P47894, Q812D8	Gene names	Isl1
Domain Architecture
Description	Insulin gene enhancer protein ISL-1 (Islet-1).

BSN_HUMAN
NC score	0.028383 (rank : 148)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	116	Target Neighborhood Hits	1537	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

DOT1L_HUMAN
NC score	0.028326 (rank : 149)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	116	Target Neighborhood Hits	660	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

CAC1B_HUMAN
NC score	0.027923 (rank : 150)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	116	Target Neighborhood Hits	257	Shared Neighborhood Hits	8
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

TRIM8_HUMAN
NC score	0.025115 (rank : 151)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	116	Target Neighborhood Hits	650	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

CS007_MOUSE
NC score	0.024453 (rank : 152)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	116	Target Neighborhood Hits	464	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

TRIM8_MOUSE
NC score	0.024243 (rank : 153)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	116	Target Neighborhood Hits	674	Shared Neighborhood Hits	20
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

SC24C_HUMAN
NC score	0.023834 (rank : 154)	θ value	1.81305 (rank : 78)
Query Neighborhood Hits	116	Target Neighborhood Hits	662	Shared Neighborhood Hits	20
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

PER3_HUMAN
NC score	0.023789 (rank : 155)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	116	Target Neighborhood Hits	479	Shared Neighborhood Hits	12
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

EVI2A_MOUSE
NC score	0.021708 (rank : 156)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	116	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	P20934	Gene names	Evi2a, Evi-2, Evi-2a, Evi2
Domain Architecture
Description	EVI2A protein precursor (Ecotropic viral integration site 2A protein).

T22D4_HUMAN
NC score	0.020925 (rank : 157)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	116	Target Neighborhood Hits	403	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

NUMBL_HUMAN
NC score	0.018829 (rank : 158)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	116	Target Neighborhood Hits	394	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

TPSN_HUMAN
NC score	0.016481 (rank : 159)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	116	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	O15533, O15210, O15272, Q5STJ8, Q5STK6, Q5STQ5, Q5STQ6, Q66K65, Q96KK7, Q9HAN8, Q9UEE0, Q9UEE4, Q9UIZ6, Q9Y6K2	Gene names	TAPBP, NGS17, TAPA
Domain Architecture
Description	Tapasin precursor (TPSN) (TPN) (TAP-binding protein) (TAP-associated protein) (NGS-17).

TSSC4_HUMAN
NC score	0.015515 (rank : 160)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	116	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y5U2, Q86VL2, Q9BRS6	Gene names	TSSC4
Domain Architecture	No domain graphic available
Description	Protein TSSC4 (Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein) (Tumor-suppressing STF cDNA 4 protein).

FRAS1_MOUSE
NC score	0.014701 (rank : 161)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	116	Target Neighborhood Hits	747	Shared Neighborhood Hits	17
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

SCNNB_MOUSE
NC score	0.014099 (rank : 162)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	116	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WU38	Gene names	Scnn1b
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit beta (Epithelial Na+ channel subunit beta) (Beta ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) (Beta NaCH).

SCNNB_HUMAN
NC score	0.011494 (rank : 163)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	116	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P51168, O60891, Q96KG2, Q9UJ32, Q9UMU5	Gene names	SCNN1B
Domain Architecture
Description	Amiloride-sensitive sodium channel subunit beta (Epithelial Na+ channel subunit beta) (Beta ENaC) (Nonvoltage-gated sodium channel 1 subunit beta) (SCNEB) (Beta NaCH) (ENaCB).

GON4L_MOUSE
NC score	0.011153 (rank : 164)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	116	Target Neighborhood Hits	455	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

MS3L1_HUMAN
NC score	0.011070 (rank : 165)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	116	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N5Y2, Q9UG70, Q9Y5Z8	Gene names	MSL3L1
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

TRI35_HUMAN
NC score	0.010975 (rank : 166)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	116	Target Neighborhood Hits	382	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

GR65_HUMAN
NC score	0.010916 (rank : 167)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	116	Target Neighborhood Hits	148	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

MY18B_HUMAN
NC score	0.010604 (rank : 168)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	116	Target Neighborhood Hits	1299	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

SYGP1_HUMAN
NC score	0.009706 (rank : 169)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	116	Target Neighborhood Hits	589	Shared Neighborhood Hits	14
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

ZDHC8_MOUSE
NC score	0.006780 (rank : 170)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	116	Target Neighborhood Hits	243	Shared Neighborhood Hits	9
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

ZN319_MOUSE
NC score	0.005985 (rank : 171)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	116	Target Neighborhood Hits	762	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ERR8	Gene names	Znf319, Zfp319
Domain Architecture	No domain graphic available
Description	Zinc finger protein 319.

ZN319_HUMAN
NC score	0.005951 (rank : 172)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	116	Target Neighborhood Hits	772	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P2F9	Gene names	ZNF319, KIAA1388
Domain Architecture	No domain graphic available
Description	Zinc finger protein 319.

PAK4_MOUSE
NC score	0.000766 (rank : 173)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	116	Target Neighborhood Hits	1098	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

ZN420_HUMAN
NC score	-0.000762 (rank : 174)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	116	Target Neighborhood Hits	759	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TAQ5	Gene names	ZNF420
Domain Architecture	No domain graphic available
Description	Zinc finger protein 420.