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Network neighborhood for query Sequence : RUNX3_MOUSE

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RUNX3_MOUSE
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RUNX3_HUMAN
θ value	0 (rank : 1)	NC score	0.978505 (rank : 2)
Query Neighborhood Hits	113	Target Neighborhood Hits	96	Shared Neighborhood Hits	45
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

RUNX3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	113
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

RUNX1_HUMAN
θ value	2.87963e-131 (rank : 3)	NC score	0.953450 (rank : 4)
Query Neighborhood Hits	113	Target Neighborhood Hits	94	Shared Neighborhood Hits	20
SwissProt Accessions	Q01196, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479	Gene names	RUNX1, AML1, CBFA2
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

RUNX1_MOUSE
θ value	1.33764e-128 (rank : 4)	NC score	0.955203 (rank : 3)
Query Neighborhood Hits	113	Target Neighborhood Hits	93	Shared Neighborhood Hits	19
SwissProt Accessions	Q03347, O08598, Q62049, Q9ESB9, Q9ET65	Gene names	Runx1, Aml1, Cbfa2, Pebp2ab
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

RUNX2_HUMAN
θ value	6.45994e-107 (rank : 5)	NC score	0.943304 (rank : 5)
Query Neighborhood Hits	113	Target Neighborhood Hits	103	Shared Neighborhood Hits	14
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

RUNX2_MOUSE
θ value	3.54468e-105 (rank : 6)	NC score	0.938492 (rank : 6)
Query Neighborhood Hits	113	Target Neighborhood Hits	119	Shared Neighborhood Hits	15
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

ENAH_MOUSE
θ value	0.0148317 (rank : 7)	NC score	0.052896 (rank : 22)
Query Neighborhood Hits	113	Target Neighborhood Hits	919	Shared Neighborhood Hits	30
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

SYNPO_HUMAN
θ value	0.0148317 (rank : 8)	NC score	0.065794 (rank : 14)
Query Neighborhood Hits	113	Target Neighborhood Hits	281	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

ATN1_HUMAN
θ value	0.0252991 (rank : 9)	NC score	0.078137 (rank : 9)
Query Neighborhood Hits	113	Target Neighborhood Hits	676	Shared Neighborhood Hits	33
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ZCH14_MOUSE
θ value	0.0252991 (rank : 10)	NC score	0.098327 (rank : 7)
Query Neighborhood Hits	113	Target Neighborhood Hits	109	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

MAST1_HUMAN
θ value	0.0330416 (rank : 11)	NC score	0.019962 (rank : 73)
Query Neighborhood Hits	113	Target Neighborhood Hits	1146	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
θ value	0.0330416 (rank : 12)	NC score	0.019969 (rank : 72)
Query Neighborhood Hits	113	Target Neighborhood Hits	1123	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

ZCH14_HUMAN
θ value	0.0563607 (rank : 13)	NC score	0.076929 (rank : 11)
Query Neighborhood Hits	113	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

HCN4_HUMAN
θ value	0.0736092 (rank : 14)	NC score	0.033229 (rank : 51)
Query Neighborhood Hits	113	Target Neighborhood Hits	303	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

EP400_HUMAN
θ value	0.0961366 (rank : 15)	NC score	0.039122 (rank : 37)
Query Neighborhood Hits	113	Target Neighborhood Hits	556	Shared Neighborhood Hits	20
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

GSCR1_HUMAN
θ value	0.0961366 (rank : 16)	NC score	0.051550 (rank : 23)
Query Neighborhood Hits	113	Target Neighborhood Hits	674	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SRRM2_HUMAN
θ value	0.0961366 (rank : 17)	NC score	0.068295 (rank : 13)
Query Neighborhood Hits	113	Target Neighborhood Hits	1296	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CIC_HUMAN
θ value	0.125558 (rank : 18)	NC score	0.054103 (rank : 20)
Query Neighborhood Hits	113	Target Neighborhood Hits	992	Shared Neighborhood Hits	50
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	0.125558 (rank : 19)	NC score	0.050457 (rank : 25)
Query Neighborhood Hits	113	Target Neighborhood Hits	742	Shared Neighborhood Hits	40
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

HXD9_HUMAN
θ value	0.163984 (rank : 20)	NC score	0.017123 (rank : 82)
Query Neighborhood Hits	113	Target Neighborhood Hits	352	Shared Neighborhood Hits	11
SwissProt Accessions	P28356	Gene names	HOXD9, HOX4C
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4C) (Hox-5.2).

NANO1_HUMAN
θ value	0.163984 (rank : 21)	NC score	0.046498 (rank : 30)
Query Neighborhood Hits	113	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WY41	Gene names	NANOS1, NOS1
Domain Architecture
Description	Nanos homolog 1 (NOS-1) (EC_Rep1a).

ADNP_HUMAN
θ value	0.21417 (rank : 22)	NC score	0.036360 (rank : 43)
Query Neighborhood Hits	113	Target Neighborhood Hits	265	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2P0, O94881, Q9UG34	Gene names	ADNP, KIAA0784
Domain Architecture
Description	Activity-dependent neuroprotector (Activity-dependent neuroprotective protein).

CHCH2_HUMAN
θ value	0.21417 (rank : 23)	NC score	0.077313 (rank : 10)
Query Neighborhood Hits	113	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6H1, Q6NZ50	Gene names	CHCHD2
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (HCV NS2 trans-regulated protein) (NS2TP).

MILK1_MOUSE
θ value	0.21417 (rank : 24)	NC score	0.057049 (rank : 19)
Query Neighborhood Hits	113	Target Neighborhood Hits	788	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

LPP_HUMAN
θ value	0.365318 (rank : 25)	NC score	0.046752 (rank : 29)
Query Neighborhood Hits	113	Target Neighborhood Hits	775	Shared Neighborhood Hits	55
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

IRS2_HUMAN
θ value	0.47712 (rank : 26)	NC score	0.047027 (rank : 27)
Query Neighborhood Hits	113	Target Neighborhood Hits	262	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

MUC2_HUMAN
θ value	0.47712 (rank : 27)	NC score	0.053605 (rank : 21)
Query Neighborhood Hits	113	Target Neighborhood Hits	906	Shared Neighborhood Hits	32
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

ATS13_MOUSE
θ value	0.62314 (rank : 28)	NC score	0.011197 (rank : 96)
Query Neighborhood Hits	113	Target Neighborhood Hits	227	Shared Neighborhood Hits	3
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

MAGC1_HUMAN
θ value	0.62314 (rank : 29)	NC score	0.037804 (rank : 39)
Query Neighborhood Hits	113	Target Neighborhood Hits	431	Shared Neighborhood Hits	21
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

TJAP1_HUMAN
θ value	0.62314 (rank : 30)	NC score	0.027288 (rank : 55)
Query Neighborhood Hits	113	Target Neighborhood Hits	214	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JTD0, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7	Gene names	TJAP1, PILT, TJP4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

AUTS2_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.036266 (rank : 44)
Query Neighborhood Hits	113	Target Neighborhood Hits	342	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

SAPS1_HUMAN
θ value	0.813845 (rank : 32)	NC score	0.037528 (rank : 41)
Query Neighborhood Hits	113	Target Neighborhood Hits	704	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

ARI1A_HUMAN
θ value	1.06291 (rank : 33)	NC score	0.081790 (rank : 8)
Query Neighborhood Hits	113	Target Neighborhood Hits	787	Shared Neighborhood Hits	35
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

EGR4_MOUSE
θ value	1.06291 (rank : 34)	NC score	0.003960 (rank : 106)
Query Neighborhood Hits	113	Target Neighborhood Hits	710	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WUF2	Gene names	Egr4
Domain Architecture
Description	Early growth response protein 4 (EGR-4).

MAST2_HUMAN
θ value	1.06291 (rank : 35)	NC score	0.016269 (rank : 85)
Query Neighborhood Hits	113	Target Neighborhood Hits	1189	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST2_MOUSE
θ value	1.06291 (rank : 36)	NC score	0.015909 (rank : 86)
Query Neighborhood Hits	113	Target Neighborhood Hits	1110	Shared Neighborhood Hits	13
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

PO3F3_MOUSE
θ value	1.06291 (rank : 37)	NC score	0.019531 (rank : 74)
Query Neighborhood Hits	113	Target Neighborhood Hits	308	Shared Neighborhood Hits	12
SwissProt Accessions	P31361	Gene names	Pou3f3, Brn-1, Brn1, Otf8
Domain Architecture
Description	POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein).

RPB1_HUMAN
θ value	1.06291 (rank : 38)	NC score	0.062764 (rank : 17)
Query Neighborhood Hits	113	Target Neighborhood Hits	362	Shared Neighborhood Hits	19
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	1.06291 (rank : 39)	NC score	0.063666 (rank : 16)
Query Neighborhood Hits	113	Target Neighborhood Hits	363	Shared Neighborhood Hits	19
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

TM108_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.044853 (rank : 33)
Query Neighborhood Hits	113	Target Neighborhood Hits	166	Shared Neighborhood Hits	16
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

CITE1_HUMAN
θ value	1.38821 (rank : 41)	NC score	0.029325 (rank : 54)
Query Neighborhood Hits	113	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q99966	Gene names	CITED1, MSG1
Domain Architecture
Description	Cbp/p300-interacting transactivator 1 (Melanocyte-specific protein 1).

CN032_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.045782 (rank : 32)
Query Neighborhood Hits	113	Target Neighborhood Hits	267	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

IDD_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.024462 (rank : 60)
Query Neighborhood Hits	113	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

PCQAP_MOUSE
θ value	1.38821 (rank : 44)	NC score	0.039284 (rank : 36)
Query Neighborhood Hits	113	Target Neighborhood Hits	506	Shared Neighborhood Hits	18
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PO3F3_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.019111 (rank : 75)
Query Neighborhood Hits	113	Target Neighborhood Hits	311	Shared Neighborhood Hits	12
SwissProt Accessions	P20264, P78379	Gene names	POU3F3, BRN1, OTF8
Domain Architecture
Description	POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein).

ZN703_HUMAN
θ value	1.38821 (rank : 46)	NC score	0.038814 (rank : 38)
Query Neighborhood Hits	113	Target Neighborhood Hits	154	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H7S9, Q5XG76	Gene names	ZNF703
Domain Architecture	No domain graphic available
Description	Zinc finger protein 703.

CHCH2_MOUSE
θ value	1.81305 (rank : 47)	NC score	0.057097 (rank : 18)
Query Neighborhood Hits	113	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D1L0, Q3TUG8	Gene names	Chchd2
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 2.

CNOT3_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.041346 (rank : 34)
Query Neighborhood Hits	113	Target Neighborhood Hits	425	Shared Neighborhood Hits	15
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
θ value	1.81305 (rank : 49)	NC score	0.050939 (rank : 24)
Query Neighborhood Hits	113	Target Neighborhood Hits	504	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT4_HUMAN
θ value	1.81305 (rank : 50)	NC score	0.036431 (rank : 42)
Query Neighborhood Hits	113	Target Neighborhood Hits	207	Shared Neighborhood Hits	14
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

HXA10_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.013169 (rank : 92)
Query Neighborhood Hits	113	Target Neighborhood Hits	334	Shared Neighborhood Hits	11
SwissProt Accessions	P31260, O43370, O43605, Q15949	Gene names	HOXA10, HOX1H
Domain Architecture
Description	Homeobox protein Hox-A10 (Hox-1H) (Hox-1.8) (PL).

IRS2_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.046777 (rank : 28)
Query Neighborhood Hits	113	Target Neighborhood Hits	248	Shared Neighborhood Hits	23
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

SC24B_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.020226 (rank : 71)
Query Neighborhood Hits	113	Target Neighborhood Hits	108	Shared Neighborhood Hits	9
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

SGIP1_MOUSE
θ value	1.81305 (rank : 54)	NC score	0.031745 (rank : 52)
Query Neighborhood Hits	113	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SYNPO_MOUSE
θ value	1.81305 (rank : 55)	NC score	0.063954 (rank : 15)
Query Neighborhood Hits	113	Target Neighborhood Hits	242	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TM108_MOUSE
θ value	1.81305 (rank : 56)	NC score	0.048672 (rank : 26)
Query Neighborhood Hits	113	Target Neighborhood Hits	336	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ARX_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.013130 (rank : 93)
Query Neighborhood Hits	113	Target Neighborhood Hits	401	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QS3	Gene names	ARX
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

ARX_MOUSE
θ value	2.36792 (rank : 58)	NC score	0.013514 (rank : 91)
Query Neighborhood Hits	113	Target Neighborhood Hits	398	Shared Neighborhood Hits	14
SwissProt Accessions	O35085, Q9QYT4	Gene names	Arx
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

ASTL_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.024420 (rank : 61)
Query Neighborhood Hits	113	Target Neighborhood Hits	252	Shared Neighborhood Hits	20
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

FOXD1_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.006548 (rank : 103)
Query Neighborhood Hits	113	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q61345	Gene names	Foxd1, Fkhl8, Freac4, Hfhbf2
Domain Architecture
Description	Forkhead box protein D1 (Forkhead-related protein FKHL8) (Forkhead- related transcription factor 4) (FREAC-4) (Brain factor 2) (HFH-BF-2).

GBX2_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.014487 (rank : 88)
Query Neighborhood Hits	113	Target Neighborhood Hits	322	Shared Neighborhood Hits	10
SwissProt Accessions	P52951, O43833, Q53RX5, Q9Y5Y1	Gene names	GBX2
Domain Architecture
Description	Homeobox protein GBX-2 (Gastrulation and brain-specific homeobox protein 2).

GBX2_MOUSE
θ value	2.36792 (rank : 62)	NC score	0.014511 (rank : 87)
Query Neighborhood Hits	113	Target Neighborhood Hits	326	Shared Neighborhood Hits	10
SwissProt Accessions	P48031	Gene names	Gbx2, Mmoxa, Stra7
Domain Architecture
Description	Homeobox protein GBX-2 (Gastrulation and brain-specific homeobox protein 2) (Homeobox protein STRA7).

IRS1_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.034774 (rank : 46)
Query Neighborhood Hits	113	Target Neighborhood Hits	109	Shared Neighborhood Hits	9
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

SP5_MOUSE
θ value	2.36792 (rank : 64)	NC score	0.003728 (rank : 108)
Query Neighborhood Hits	113	Target Neighborhood Hits	821	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JHX2	Gene names	Sp5
Domain Architecture
Description	Transcription factor Sp5.

ARI1B_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.034306 (rank : 47)
Query Neighborhood Hits	113	Target Neighborhood Hits	567	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ASH2L_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.018506 (rank : 77)
Query Neighborhood Hits	113	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBL3, O60659, O60660, Q96B62	Gene names	ASH2L
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

CCNK_MOUSE
θ value	3.0926 (rank : 67)	NC score	0.025641 (rank : 58)
Query Neighborhood Hits	113	Target Neighborhood Hits	350	Shared Neighborhood Hits	13
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CNOT4_MOUSE
θ value	3.0926 (rank : 68)	NC score	0.035611 (rank : 45)
Query Neighborhood Hits	113	Target Neighborhood Hits	277	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

HCN4_MOUSE
θ value	3.0926 (rank : 69)	NC score	0.033577 (rank : 49)
Query Neighborhood Hits	113	Target Neighborhood Hits	284	Shared Neighborhood Hits	13
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

MAFB_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.018917 (rank : 76)
Query Neighborhood Hits	113	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5Q3, Q9H1F1	Gene names	MAFB, KRML
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B).

PO121_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.021830 (rank : 67)
Query Neighborhood Hits	113	Target Neighborhood Hits	344	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

SP5_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.003599 (rank : 109)
Query Neighborhood Hits	113	Target Neighborhood Hits	832	Shared Neighborhood Hits	16
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

SRRM2_MOUSE
θ value	3.0926 (rank : 73)	NC score	0.070867 (rank : 12)
Query Neighborhood Hits	113	Target Neighborhood Hits	1470	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TBX10_MOUSE
θ value	3.0926 (rank : 74)	NC score	0.007536 (rank : 102)
Query Neighborhood Hits	113	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q810F8, O54841, Q6QH75	Gene names	Tbx10, Tbx13, Tbx7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10) (T-box protein 13) (MmTBX7).

CCDC4_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.027022 (rank : 56)
Query Neighborhood Hits	113	Target Neighborhood Hits	104	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZU67, Q58A26, Q58A27	Gene names	CCDC4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 4.

MAFB_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.018029 (rank : 79)
Query Neighborhood Hits	113	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	P54841	Gene names	Mafb, Krml, Maf1
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor MAF1) (Segmentation protein KR) (Kreisler).

PHF1_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.033303 (rank : 50)
Query Neighborhood Hits	113	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

RREB1_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.008079 (rank : 100)
Query Neighborhood Hits	113	Target Neighborhood Hits	879	Shared Neighborhood Hits	16
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

SYNJ1_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.024468 (rank : 59)
Query Neighborhood Hits	113	Target Neighborhood Hits	516	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TS101_MOUSE
θ value	4.03905 (rank : 80)	NC score	0.024128 (rank : 64)
Query Neighborhood Hits	113	Target Neighborhood Hits	312	Shared Neighborhood Hits	5
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

ATX2L_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.045928 (rank : 31)
Query Neighborhood Hits	113	Target Neighborhood Hits	401	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

CDON_MOUSE
θ value	5.27518 (rank : 82)	NC score	0.002790 (rank : 112)
Query Neighborhood Hits	113	Target Neighborhood Hits	410	Shared Neighborhood Hits	2
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CDX2_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.010934 (rank : 97)
Query Neighborhood Hits	113	Target Neighborhood Hits	330	Shared Neighborhood Hits	10
SwissProt Accessions	Q99626, O00503, Q969L8	Gene names	CDX2, CDX3
Domain Architecture
Description	Homeobox protein CDX-2 (Caudal-type homeobox protein 2) (CDX-3).

DACH1_MOUSE
θ value	5.27518 (rank : 84)	NC score	0.013683 (rank : 90)
Query Neighborhood Hits	113	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

DBP_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.011961 (rank : 95)
Query Neighborhood Hits	113	Target Neighborhood Hits	137	Shared Neighborhood Hits	5
SwissProt Accessions	Q60925, Q8VCX3	Gene names	Dbp
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein).

EYA2_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.008330 (rank : 99)
Query Neighborhood Hits	113	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	O00167, Q5JSW8, Q96CV6, Q96H97, Q99503, Q99812, Q9BWF6, Q9H4S3, Q9H4S9, Q9NPZ4, Q9UIX7	Gene names	EYA2, EAB1
Domain Architecture
Description	Eyes absent homolog 2 (EC 3.1.3.48).

NCOA5_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.017815 (rank : 80)
Query Neighborhood Hits	113	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCD5, Q6HA99, Q9H1F2, Q9H2T2, Q9H4Y9	Gene names	NCOA5, KIAA1637
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

NFRKB_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.024166 (rank : 63)
Query Neighborhood Hits	113	Target Neighborhood Hits	211	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NU214_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.034183 (rank : 48)
Query Neighborhood Hits	113	Target Neighborhood Hits	657	Shared Neighborhood Hits	30
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

SIN3A_MOUSE
θ value	5.27518 (rank : 90)	NC score	0.037785 (rank : 40)
Query Neighborhood Hits	113	Target Neighborhood Hits	169	Shared Neighborhood Hits	11
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

ATF6B_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.012509 (rank : 94)
Query Neighborhood Hits	113	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

EGR1_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.003923 (rank : 107)
Query Neighborhood Hits	113	Target Neighborhood Hits	788	Shared Neighborhood Hits	12
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

GLI1_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.003053 (rank : 110)
Query Neighborhood Hits	113	Target Neighborhood Hits	828	Shared Neighborhood Hits	19
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

HGS_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.029721 (rank : 53)
Query Neighborhood Hits	113	Target Neighborhood Hits	589	Shared Neighborhood Hits	24
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

MAST4_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.020422 (rank : 70)
Query Neighborhood Hits	113	Target Neighborhood Hits	1804	Shared Neighborhood Hits	50
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NPTXR_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.007868 (rank : 101)
Query Neighborhood Hits	113	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	O95502	Gene names	NPTXR
Domain Architecture
Description	Neuronal pentraxin receptor.

PI5PA_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.039550 (rank : 35)
Query Neighborhood Hits	113	Target Neighborhood Hits	331	Shared Neighborhood Hits	18
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RBM14_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.022621 (rank : 66)
Query Neighborhood Hits	113	Target Neighborhood Hits	213	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PK6, O75932, Q53GV1, Q68DQ9, Q96PK5	Gene names	RBM14, SIP
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein).

RBM14_MOUSE
θ value	6.88961 (rank : 99)	NC score	0.021448 (rank : 69)
Query Neighborhood Hits	113	Target Neighborhood Hits	217	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C2Q3, Q3TJB6, Q91Z21, Q9DBI6	Gene names	Rbm14
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14).

SSBP3_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.016319 (rank : 83)
Query Neighborhood Hits	113	Target Neighborhood Hits	132	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
θ value	6.88961 (rank : 101)	NC score	0.016319 (rank : 84)
Query Neighborhood Hits	113	Target Neighborhood Hits	132	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

BAT2_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.024236 (rank : 62)
Query Neighborhood Hits	113	Target Neighborhood Hits	931	Shared Neighborhood Hits	42
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DDX54_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.002192 (rank : 113)
Query Neighborhood Hits	113	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

ENAH_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.018423 (rank : 78)
Query Neighborhood Hits	113	Target Neighborhood Hits	784	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

FOXD1_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.004775 (rank : 105)
Query Neighborhood Hits	113	Target Neighborhood Hits	122	Shared Neighborhood Hits	5
SwissProt Accessions	Q16676, Q12949	Gene names	FOXD1, FKHL8, FREAC4
Domain Architecture
Description	Forkhead box protein D1 (Forkhead-related protein FKHL8) (Forkhead- related transcription factor 4) (FREAC-4).

IL3B2_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.014020 (rank : 89)
Query Neighborhood Hits	113	Target Neighborhood Hits	372	Shared Neighborhood Hits	14
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

KBTBB_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.005541 (rank : 104)
Query Neighborhood Hits	113	Target Neighborhood Hits	195	Shared Neighborhood Hits	5
SwissProt Accessions	O94819	Gene names	KBTBD11, KIAA0711, KLHDC7C
Domain Architecture	No domain graphic available
Description	Kelch repeat and BTB domain-containing protein 11 (Kelch domain- containing protein 7B).

NRG3_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.023591 (rank : 65)
Query Neighborhood Hits	113	Target Neighborhood Hits	119	Shared Neighborhood Hits	4
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

PHF1_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.025830 (rank : 57)
Query Neighborhood Hits	113	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PRP1_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.017647 (rank : 81)
Query Neighborhood Hits	113	Target Neighborhood Hits	385	Shared Neighborhood Hits	16
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

TAF4_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.021448 (rank : 68)
Query Neighborhood Hits	113	Target Neighborhood Hits	687	Shared Neighborhood Hits	24
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

WASF3_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.009637 (rank : 98)
Query Neighborhood Hits	113	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

ZBTB4_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.002799 (rank : 111)
Query Neighborhood Hits	113	Target Neighborhood Hits	926	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

Hits sorted by NC score

RUNX3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	113
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

RUNX3_HUMAN
NC score	0.978505 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	113	Target Neighborhood Hits	96	Shared Neighborhood Hits	45
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

RUNX1_MOUSE
NC score	0.955203 (rank : 3)	θ value	1.33764e-128 (rank : 4)
Query Neighborhood Hits	113	Target Neighborhood Hits	93	Shared Neighborhood Hits	19
SwissProt Accessions	Q03347, O08598, Q62049, Q9ESB9, Q9ET65	Gene names	Runx1, Aml1, Cbfa2, Pebp2ab
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

RUNX1_HUMAN
NC score	0.953450 (rank : 4)	θ value	2.87963e-131 (rank : 3)
Query Neighborhood Hits	113	Target Neighborhood Hits	94	Shared Neighborhood Hits	20
SwissProt Accessions	Q01196, O60472, O60473, O76047, O76089, Q13081, Q13755, Q13756, Q13757, Q13758, Q13759, Q15341, Q15343, Q16122, Q16284, Q16285, Q16286, Q16346, Q16347, Q92479	Gene names	RUNX1, AML1, CBFA2
Domain Architecture
Description	Runt-related transcription factor 1 (Core-binding factor, alpha 2 subunit) (CBF-alpha 2) (Acute myeloid leukemia 1 protein) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEBP2-alpha B) (PEA2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit).

RUNX2_HUMAN
NC score	0.943304 (rank : 5)	θ value	6.45994e-107 (rank : 5)
Query Neighborhood Hits	113	Target Neighborhood Hits	103	Shared Neighborhood Hits	14
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

RUNX2_MOUSE
NC score	0.938492 (rank : 6)	θ value	3.54468e-105 (rank : 6)
Query Neighborhood Hits	113	Target Neighborhood Hits	119	Shared Neighborhood Hits	15
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

ZCH14_MOUSE
NC score	0.098327 (rank : 7)	θ value	0.0252991 (rank : 10)
Query Neighborhood Hits	113	Target Neighborhood Hits	109	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

ARI1A_HUMAN
NC score	0.081790 (rank : 8)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	113	Target Neighborhood Hits	787	Shared Neighborhood Hits	35
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ATN1_HUMAN
NC score	0.078137 (rank : 9)	θ value	0.0252991 (rank : 9)
Query Neighborhood Hits	113	Target Neighborhood Hits	676	Shared Neighborhood Hits	33
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CHCH2_HUMAN
NC score	0.077313 (rank : 10)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	113	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6H1, Q6NZ50	Gene names	CHCHD2
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (HCV NS2 trans-regulated protein) (NS2TP).

ZCH14_HUMAN
NC score	0.076929 (rank : 11)	θ value	0.0563607 (rank : 13)
Query Neighborhood Hits	113	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

SRRM2_MOUSE
NC score	0.070867 (rank : 12)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	113	Target Neighborhood Hits	1470	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SRRM2_HUMAN
NC score	0.068295 (rank : 13)	θ value	0.0961366 (rank : 17)
Query Neighborhood Hits	113	Target Neighborhood Hits	1296	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYNPO_HUMAN
NC score	0.065794 (rank : 14)	θ value	0.0148317 (rank : 8)
Query Neighborhood Hits	113	Target Neighborhood Hits	281	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

SYNPO_MOUSE
NC score	0.063954 (rank : 15)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	113	Target Neighborhood Hits	242	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

RPB1_MOUSE
NC score	0.063666 (rank : 16)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	113	Target Neighborhood Hits	363	Shared Neighborhood Hits	19
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.062764 (rank : 17)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	113	Target Neighborhood Hits	362	Shared Neighborhood Hits	19
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

CHCH2_MOUSE
NC score	0.057097 (rank : 18)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	113	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D1L0, Q3TUG8	Gene names	Chchd2
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 2.

MILK1_MOUSE
NC score	0.057049 (rank : 19)	θ value	0.21417 (rank : 24)
Query Neighborhood Hits	113	Target Neighborhood Hits	788	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CIC_HUMAN
NC score	0.054103 (rank : 20)	θ value	0.125558 (rank : 18)
Query Neighborhood Hits	113	Target Neighborhood Hits	992	Shared Neighborhood Hits	50
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MUC2_HUMAN
NC score	0.053605 (rank : 21)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	113	Target Neighborhood Hits	906	Shared Neighborhood Hits	32
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

ENAH_MOUSE
NC score	0.052896 (rank : 22)	θ value	0.0148317 (rank : 7)
Query Neighborhood Hits	113	Target Neighborhood Hits	919	Shared Neighborhood Hits	30
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

GSCR1_HUMAN
NC score	0.051550 (rank : 23)	θ value	0.0961366 (rank : 16)
Query Neighborhood Hits	113	Target Neighborhood Hits	674	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

CNOT3_MOUSE
NC score	0.050939 (rank : 24)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	113	Target Neighborhood Hits	504	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CIC_MOUSE
NC score	0.050457 (rank : 25)	θ value	0.125558 (rank : 19)
Query Neighborhood Hits	113	Target Neighborhood Hits	742	Shared Neighborhood Hits	40
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

TM108_MOUSE
NC score	0.048672 (rank : 26)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	113	Target Neighborhood Hits	336	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

IRS2_HUMAN
NC score	0.047027 (rank : 27)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	113	Target Neighborhood Hits	262	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

IRS2_MOUSE
NC score	0.046777 (rank : 28)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	113	Target Neighborhood Hits	248	Shared Neighborhood Hits	23
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

LPP_HUMAN
NC score	0.046752 (rank : 29)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	113	Target Neighborhood Hits	775	Shared Neighborhood Hits	55
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

NANO1_HUMAN
NC score	0.046498 (rank : 30)	θ value	0.163984 (rank : 21)
Query Neighborhood Hits	113	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WY41	Gene names	NANOS1, NOS1
Domain Architecture
Description	Nanos homolog 1 (NOS-1) (EC_Rep1a).

ATX2L_MOUSE
NC score	0.045928 (rank : 31)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	113	Target Neighborhood Hits	401	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

CN032_HUMAN
NC score	0.045782 (rank : 32)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	113	Target Neighborhood Hits	267	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

TM108_HUMAN
NC score	0.044853 (rank : 33)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	113	Target Neighborhood Hits	166	Shared Neighborhood Hits	16
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

CNOT3_HUMAN
NC score	0.041346 (rank : 34)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	113	Target Neighborhood Hits	425	Shared Neighborhood Hits	15
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

PI5PA_MOUSE
NC score	0.039550 (rank : 35)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	113	Target Neighborhood Hits	331	Shared Neighborhood Hits	18
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PCQAP_MOUSE
NC score	0.039284 (rank : 36)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	113	Target Neighborhood Hits	506	Shared Neighborhood Hits	18
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

EP400_HUMAN
NC score	0.039122 (rank : 37)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	113	Target Neighborhood Hits	556	Shared Neighborhood Hits	20
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

ZN703_HUMAN
NC score	0.038814 (rank : 38)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	113	Target Neighborhood Hits	154	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H7S9, Q5XG76	Gene names	ZNF703
Domain Architecture	No domain graphic available
Description	Zinc finger protein 703.

MAGC1_HUMAN
NC score	0.037804 (rank : 39)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	113	Target Neighborhood Hits	431	Shared Neighborhood Hits	21
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

SIN3A_MOUSE
NC score	0.037785 (rank : 40)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	113	Target Neighborhood Hits	169	Shared Neighborhood Hits	11
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

SAPS1_HUMAN
NC score	0.037528 (rank : 41)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	113	Target Neighborhood Hits	704	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CNOT4_HUMAN
NC score	0.036431 (rank : 42)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	113	Target Neighborhood Hits	207	Shared Neighborhood Hits	14
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

ADNP_HUMAN
NC score	0.036360 (rank : 43)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	113	Target Neighborhood Hits	265	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H2P0, O94881, Q9UG34	Gene names	ADNP, KIAA0784
Domain Architecture
Description	Activity-dependent neuroprotector (Activity-dependent neuroprotective protein).

AUTS2_HUMAN
NC score	0.036266 (rank : 44)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	113	Target Neighborhood Hits	342	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

CNOT4_MOUSE
NC score	0.035611 (rank : 45)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	113	Target Neighborhood Hits	277	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

IRS1_HUMAN
NC score	0.034774 (rank : 46)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	113	Target Neighborhood Hits	109	Shared Neighborhood Hits	9
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

ARI1B_HUMAN
NC score	0.034306 (rank : 47)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	113	Target Neighborhood Hits	567	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

NU214_HUMAN
NC score	0.034183 (rank : 48)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	113	Target Neighborhood Hits	657	Shared Neighborhood Hits	30
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

HCN4_MOUSE
NC score	0.033577 (rank : 49)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	113	Target Neighborhood Hits	284	Shared Neighborhood Hits	13
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

PHF1_MOUSE
NC score	0.033303 (rank : 50)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	113	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

HCN4_HUMAN
NC score	0.033229 (rank : 51)	θ value	0.0736092 (rank : 14)
Query Neighborhood Hits	113	Target Neighborhood Hits	303	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

SGIP1_MOUSE
NC score	0.031745 (rank : 52)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	113	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

HGS_MOUSE
NC score	0.029721 (rank : 53)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	113	Target Neighborhood Hits	589	Shared Neighborhood Hits	24
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

CITE1_HUMAN
NC score	0.029325 (rank : 54)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	113	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q99966	Gene names	CITED1, MSG1
Domain Architecture
Description	Cbp/p300-interacting transactivator 1 (Melanocyte-specific protein 1).

TJAP1_HUMAN
NC score	0.027288 (rank : 55)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	113	Target Neighborhood Hits	214	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JTD0, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7	Gene names	TJAP1, PILT, TJP4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

CCDC4_HUMAN
NC score	0.027022 (rank : 56)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	113	Target Neighborhood Hits	104	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZU67, Q58A26, Q58A27	Gene names	CCDC4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 4.

PHF1_HUMAN
NC score	0.025830 (rank : 57)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	113	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

CCNK_MOUSE
NC score	0.025641 (rank : 58)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	113	Target Neighborhood Hits	350	Shared Neighborhood Hits	13
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

SYNJ1_MOUSE
NC score	0.024468 (rank : 59)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	113	Target Neighborhood Hits	516	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

IDD_HUMAN
NC score	0.024462 (rank : 60)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	113	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

ASTL_HUMAN
NC score	0.024420 (rank : 61)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	113	Target Neighborhood Hits	252	Shared Neighborhood Hits	20
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

BAT2_HUMAN
NC score	0.024236 (rank : 62)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	113	Target Neighborhood Hits	931	Shared Neighborhood Hits	42
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

NFRKB_HUMAN
NC score	0.024166 (rank : 63)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	113	Target Neighborhood Hits	211	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

TS101_MOUSE
NC score	0.024128 (rank : 64)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	113	Target Neighborhood Hits	312	Shared Neighborhood Hits	5
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

NRG3_HUMAN
NC score	0.023591 (rank : 65)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	113	Target Neighborhood Hits	119	Shared Neighborhood Hits	4
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

RBM14_HUMAN
NC score	0.022621 (rank : 66)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	113	Target Neighborhood Hits	213	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PK6, O75932, Q53GV1, Q68DQ9, Q96PK5	Gene names	RBM14, SIP
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein).

PO121_HUMAN
NC score	0.021830 (rank : 67)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	113	Target Neighborhood Hits	344	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

TAF4_HUMAN
NC score	0.021448 (rank : 68)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	113	Target Neighborhood Hits	687	Shared Neighborhood Hits	24
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

RBM14_MOUSE
NC score	0.021448 (rank : 69)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	113	Target Neighborhood Hits	217	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C2Q3, Q3TJB6, Q91Z21, Q9DBI6	Gene names	Rbm14
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14).

MAST4_HUMAN
NC score	0.020422 (rank : 70)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	113	Target Neighborhood Hits	1804	Shared Neighborhood Hits	50
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

SC24B_HUMAN
NC score	0.020226 (rank : 71)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	113	Target Neighborhood Hits	108	Shared Neighborhood Hits	9
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

MAST1_MOUSE
NC score	0.019969 (rank : 72)	θ value	0.0330416 (rank : 12)
Query Neighborhood Hits	113	Target Neighborhood Hits	1123	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_HUMAN
NC score	0.019962 (rank : 73)	θ value	0.0330416 (rank : 11)
Query Neighborhood Hits	113	Target Neighborhood Hits	1146	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

PO3F3_MOUSE
NC score	0.019531 (rank : 74)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	113	Target Neighborhood Hits	308	Shared Neighborhood Hits	12
SwissProt Accessions	P31361	Gene names	Pou3f3, Brn-1, Brn1, Otf8
Domain Architecture
Description	POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein).

PO3F3_HUMAN
NC score	0.019111 (rank : 75)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	113	Target Neighborhood Hits	311	Shared Neighborhood Hits	12
SwissProt Accessions	P20264, P78379	Gene names	POU3F3, BRN1, OTF8
Domain Architecture
Description	POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein).

MAFB_HUMAN
NC score	0.018917 (rank : 76)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	113	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5Q3, Q9H1F1	Gene names	MAFB, KRML
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B).

ASH2L_HUMAN
NC score	0.018506 (rank : 77)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	113	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBL3, O60659, O60660, Q96B62	Gene names	ASH2L
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

ENAH_HUMAN
NC score	0.018423 (rank : 78)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	113	Target Neighborhood Hits	784	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

MAFB_MOUSE
NC score	0.018029 (rank : 79)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	113	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	P54841	Gene names	Mafb, Krml, Maf1
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor MAF1) (Segmentation protein KR) (Kreisler).

NCOA5_HUMAN
NC score	0.017815 (rank : 80)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	113	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCD5, Q6HA99, Q9H1F2, Q9H2T2, Q9H4Y9	Gene names	NCOA5, KIAA1637
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

PRP1_HUMAN
NC score	0.017647 (rank : 81)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	113	Target Neighborhood Hits	385	Shared Neighborhood Hits	16
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

HXD9_HUMAN
NC score	0.017123 (rank : 82)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	113	Target Neighborhood Hits	352	Shared Neighborhood Hits	11
SwissProt Accessions	P28356	Gene names	HOXD9, HOX4C
Domain Architecture
Description	Homeobox protein Hox-D9 (Hox-4C) (Hox-5.2).

SSBP3_HUMAN
NC score	0.016319 (rank : 83)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	113	Target Neighborhood Hits	132	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BWW4, Q9BTM0, Q9BWW3	Gene names	SSBP3, SSDP, SSDP1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein).

SSBP3_MOUSE
NC score	0.016319 (rank : 84)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	113	Target Neighborhood Hits	132	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D032, Q99LC6, Q9EQP3	Gene names	Ssbp3, Last, Ssdp1
Domain Architecture
Description	Single-stranded DNA-binding protein 3 (Sequence-specific single- stranded-DNA-binding protein) (Lck-associated signal transducer).

MAST2_HUMAN
NC score	0.016269 (rank : 85)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	113	Target Neighborhood Hits	1189	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST2_MOUSE
NC score	0.015909 (rank : 86)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	113	Target Neighborhood Hits	1110	Shared Neighborhood Hits	13
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

GBX2_MOUSE
NC score	0.014511 (rank : 87)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	113	Target Neighborhood Hits	326	Shared Neighborhood Hits	10
SwissProt Accessions	P48031	Gene names	Gbx2, Mmoxa, Stra7
Domain Architecture
Description	Homeobox protein GBX-2 (Gastrulation and brain-specific homeobox protein 2) (Homeobox protein STRA7).

GBX2_HUMAN
NC score	0.014487 (rank : 88)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	113	Target Neighborhood Hits	322	Shared Neighborhood Hits	10
SwissProt Accessions	P52951, O43833, Q53RX5, Q9Y5Y1	Gene names	GBX2
Domain Architecture
Description	Homeobox protein GBX-2 (Gastrulation and brain-specific homeobox protein 2).

IL3B2_MOUSE
NC score	0.014020 (rank : 89)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	113	Target Neighborhood Hits	372	Shared Neighborhood Hits	14
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

DACH1_MOUSE
NC score	0.013683 (rank : 90)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	113	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

ARX_MOUSE
NC score	0.013514 (rank : 91)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	113	Target Neighborhood Hits	398	Shared Neighborhood Hits	14
SwissProt Accessions	O35085, Q9QYT4	Gene names	Arx
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

HXA10_HUMAN
NC score	0.013169 (rank : 92)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	113	Target Neighborhood Hits	334	Shared Neighborhood Hits	11
SwissProt Accessions	P31260, O43370, O43605, Q15949	Gene names	HOXA10, HOX1H
Domain Architecture
Description	Homeobox protein Hox-A10 (Hox-1H) (Hox-1.8) (PL).

ARX_HUMAN
NC score	0.013130 (rank : 93)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	113	Target Neighborhood Hits	401	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QS3	Gene names	ARX
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

ATF6B_MOUSE
NC score	0.012509 (rank : 94)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	113	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

DBP_MOUSE
NC score	0.011961 (rank : 95)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	113	Target Neighborhood Hits	137	Shared Neighborhood Hits	5
SwissProt Accessions	Q60925, Q8VCX3	Gene names	Dbp
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein).

ATS13_MOUSE
NC score	0.011197 (rank : 96)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	113	Target Neighborhood Hits	227	Shared Neighborhood Hits	3
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

CDX2_HUMAN
NC score	0.010934 (rank : 97)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	113	Target Neighborhood Hits	330	Shared Neighborhood Hits	10
SwissProt Accessions	Q99626, O00503, Q969L8	Gene names	CDX2, CDX3
Domain Architecture
Description	Homeobox protein CDX-2 (Caudal-type homeobox protein 2) (CDX-3).

WASF3_MOUSE
NC score	0.009637 (rank : 98)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	113	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

EYA2_HUMAN
NC score	0.008330 (rank : 99)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	113	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	O00167, Q5JSW8, Q96CV6, Q96H97, Q99503, Q99812, Q9BWF6, Q9H4S3, Q9H4S9, Q9NPZ4, Q9UIX7	Gene names	EYA2, EAB1
Domain Architecture
Description	Eyes absent homolog 2 (EC 3.1.3.48).

RREB1_HUMAN
NC score	0.008079 (rank : 100)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	113	Target Neighborhood Hits	879	Shared Neighborhood Hits	16
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

NPTXR_HUMAN
NC score	0.007868 (rank : 101)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	113	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	O95502	Gene names	NPTXR
Domain Architecture
Description	Neuronal pentraxin receptor.

TBX10_MOUSE
NC score	0.007536 (rank : 102)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	113	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q810F8, O54841, Q6QH75	Gene names	Tbx10, Tbx13, Tbx7
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX10 (T-box protein 10) (T-box protein 13) (MmTBX7).

FOXD1_MOUSE
NC score	0.006548 (rank : 103)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	113	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q61345	Gene names	Foxd1, Fkhl8, Freac4, Hfhbf2
Domain Architecture
Description	Forkhead box protein D1 (Forkhead-related protein FKHL8) (Forkhead- related transcription factor 4) (FREAC-4) (Brain factor 2) (HFH-BF-2).

KBTBB_HUMAN
NC score	0.005541 (rank : 104)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	113	Target Neighborhood Hits	195	Shared Neighborhood Hits	5
SwissProt Accessions	O94819	Gene names	KBTBD11, KIAA0711, KLHDC7C
Domain Architecture	No domain graphic available
Description	Kelch repeat and BTB domain-containing protein 11 (Kelch domain- containing protein 7B).

FOXD1_HUMAN
NC score	0.004775 (rank : 105)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	113	Target Neighborhood Hits	122	Shared Neighborhood Hits	5
SwissProt Accessions	Q16676, Q12949	Gene names	FOXD1, FKHL8, FREAC4
Domain Architecture
Description	Forkhead box protein D1 (Forkhead-related protein FKHL8) (Forkhead- related transcription factor 4) (FREAC-4).

EGR4_MOUSE
NC score	0.003960 (rank : 106)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	113	Target Neighborhood Hits	710	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WUF2	Gene names	Egr4
Domain Architecture
Description	Early growth response protein 4 (EGR-4).

EGR1_HUMAN
NC score	0.003923 (rank : 107)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	113	Target Neighborhood Hits	788	Shared Neighborhood Hits	12
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

SP5_MOUSE
NC score	0.003728 (rank : 108)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	113	Target Neighborhood Hits	821	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JHX2	Gene names	Sp5
Domain Architecture
Description	Transcription factor Sp5.

SP5_HUMAN
NC score	0.003599 (rank : 109)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	113	Target Neighborhood Hits	832	Shared Neighborhood Hits	16
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

GLI1_HUMAN
NC score	0.003053 (rank : 110)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	113	Target Neighborhood Hits	828	Shared Neighborhood Hits	19
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

ZBTB4_HUMAN
NC score	0.002799 (rank : 111)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	113	Target Neighborhood Hits	926	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

CDON_MOUSE
NC score	0.002790 (rank : 112)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	113	Target Neighborhood Hits	410	Shared Neighborhood Hits	2
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

DDX54_HUMAN
NC score	0.002192 (rank : 113)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	113	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).