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Network neighborhood for query Sequence : CRUM2_HUMAN

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CRUM2_HUMAN
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CRUM1_HUMAN
θ value	0 (rank : 1)	NC score	0.980167 (rank : 3)
Query Neighborhood Hits	453	Target Neighborhood Hits	457	Shared Neighborhood Hits	384
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	0 (rank : 2)	NC score	0.981995 (rank : 2)
Query Neighborhood Hits	453	Target Neighborhood Hits	444	Shared Neighborhood Hits	379
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	453	Target Neighborhood Hits	453	Shared Neighborhood Hits	453
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

NOTC1_MOUSE
θ value	4.80189e-94 (rank : 4)	NC score	0.885255 (rank : 20)
Query Neighborhood Hits	453	Target Neighborhood Hits	916	Shared Neighborhood Hits	412
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_MOUSE
θ value	8.19079e-94 (rank : 5)	NC score	0.860819 (rank : 23)
Query Neighborhood Hits	453	Target Neighborhood Hits	1069	Shared Neighborhood Hits	409
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_HUMAN
θ value	4.49445e-92 (rank : 6)	NC score	0.857024 (rank : 27)
Query Neighborhood Hits	453	Target Neighborhood Hits	1113	Shared Neighborhood Hits	416
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC1_HUMAN
θ value	5.86991e-92 (rank : 7)	NC score	0.860384 (rank : 24)
Query Neighborhood Hits	453	Target Neighborhood Hits	906	Shared Neighborhood Hits	406
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_MOUSE
θ value	8.47616e-91 (rank : 8)	NC score	0.860162 (rank : 25)
Query Neighborhood Hits	453	Target Neighborhood Hits	975	Shared Neighborhood Hits	412
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_MOUSE
θ value	1.10702e-90 (rank : 9)	NC score	0.843148 (rank : 36)
Query Neighborhood Hits	453	Target Neighborhood Hits	872	Shared Neighborhood Hits	414
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC3_HUMAN
θ value	1.88829e-90 (rank : 10)	NC score	0.859933 (rank : 26)
Query Neighborhood Hits	453	Target Neighborhood Hits	1062	Shared Neighborhood Hits	413
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_HUMAN
θ value	6.71607e-88 (rank : 11)	NC score	0.844660 (rank : 32)
Query Neighborhood Hits	453	Target Neighborhood Hits	905	Shared Neighborhood Hits	416
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

JAG2_HUMAN
θ value	1.89267e-82 (rank : 12)	NC score	0.954587 (rank : 6)
Query Neighborhood Hits	453	Target Neighborhood Hits	491	Shared Neighborhood Hits	388
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	1.77149e-80 (rank : 13)	NC score	0.953965 (rank : 7)
Query Neighborhood Hits	453	Target Neighborhood Hits	504	Shared Neighborhood Hits	382
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

JAG1_MOUSE
θ value	2.31364e-80 (rank : 14)	NC score	0.951373 (rank : 11)
Query Neighborhood Hits	453	Target Neighborhood Hits	518	Shared Neighborhood Hits	386
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG1_HUMAN
θ value	1.14825e-79 (rank : 15)	NC score	0.951994 (rank : 10)
Query Neighborhood Hits	453	Target Neighborhood Hits	514	Shared Neighborhood Hits	392
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

DNER_HUMAN
θ value	2.4834e-66 (rank : 16)	NC score	0.957909 (rank : 4)
Query Neighborhood Hits	453	Target Neighborhood Hits	460	Shared Neighborhood Hits	368
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DLL1_HUMAN
θ value	3.58603e-65 (rank : 17)	NC score	0.953640 (rank : 9)
Query Neighborhood Hits	453	Target Neighborhood Hits	455	Shared Neighborhood Hits	371
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	1.15359e-63 (rank : 18)	NC score	0.953893 (rank : 8)
Query Neighborhood Hits	453	Target Neighborhood Hits	456	Shared Neighborhood Hits	382
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DNER_MOUSE
θ value	2.56992e-63 (rank : 19)	NC score	0.957683 (rank : 5)
Query Neighborhood Hits	453	Target Neighborhood Hits	413	Shared Neighborhood Hits	359
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

DLL4_MOUSE
θ value	1.11734e-58 (rank : 20)	NC score	0.949265 (rank : 13)
Query Neighborhood Hits	453	Target Neighborhood Hits	440	Shared Neighborhood Hits	364
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_HUMAN
θ value	2.7521e-57 (rank : 21)	NC score	0.950717 (rank : 12)
Query Neighborhood Hits	453	Target Neighborhood Hits	435	Shared Neighborhood Hits	363
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

SLIT2_MOUSE
θ value	1.788e-48 (rank : 22)	NC score	0.691476 (rank : 104)
Query Neighborhood Hits	453	Target Neighborhood Hits	684	Shared Neighborhood Hits	347
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_HUMAN
θ value	3.98324e-48 (rank : 23)	NC score	0.696775 (rank : 101)
Query Neighborhood Hits	453	Target Neighborhood Hits	708	Shared Neighborhood Hits	359
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT3_MOUSE
θ value	1.15895e-47 (rank : 24)	NC score	0.679979 (rank : 107)
Query Neighborhood Hits	453	Target Neighborhood Hits	700	Shared Neighborhood Hits	350
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SLIT3_HUMAN
θ value	2.18568e-46 (rank : 25)	NC score	0.675118 (rank : 108)
Query Neighborhood Hits	453	Target Neighborhood Hits	682	Shared Neighborhood Hits	348
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

CUBN_HUMAN
θ value	2.41655e-45 (rank : 26)	NC score	0.768175 (rank : 72)
Query Neighborhood Hits	453	Target Neighborhood Hits	482	Shared Neighborhood Hits	345
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

DLL3_MOUSE
θ value	7.03111e-45 (rank : 27)	NC score	0.945746 (rank : 14)
Query Neighborhood Hits	453	Target Neighborhood Hits	399	Shared Neighborhood Hits	352
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

CUBN_MOUSE
θ value	9.18288e-45 (rank : 28)	NC score	0.771963 (rank : 70)
Query Neighborhood Hits	453	Target Neighborhood Hits	477	Shared Neighborhood Hits	341
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

SLIT1_HUMAN
θ value	1.32601e-43 (rank : 29)	NC score	0.703976 (rank : 99)
Query Neighborhood Hits	453	Target Neighborhood Hits	700	Shared Neighborhood Hits	354
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT1_MOUSE
θ value	1.32601e-43 (rank : 30)	NC score	0.705572 (rank : 97)
Query Neighborhood Hits	453	Target Neighborhood Hits	715	Shared Neighborhood Hits	358
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

LTBP4_MOUSE
θ value	1.46607e-42 (rank : 31)	NC score	0.870117 (rank : 22)
Query Neighborhood Hits	453	Target Neighborhood Hits	607	Shared Neighborhood Hits	348
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

EGFL9_MOUSE
θ value	2.50074e-42 (rank : 32)	NC score	0.942307 (rank : 17)
Query Neighborhood Hits	453	Target Neighborhood Hits	379	Shared Neighborhood Hits	338
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

DLL3_HUMAN
θ value	4.2656e-42 (rank : 33)	NC score	0.943679 (rank : 15)
Query Neighborhood Hits	453	Target Neighborhood Hits	419	Shared Neighborhood Hits	355
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

EGFL9_HUMAN
θ value	9.50281e-42 (rank : 34)	NC score	0.943674 (rank : 16)
Query Neighborhood Hits	453	Target Neighborhood Hits	365	Shared Neighborhood Hits	334
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

CELR2_HUMAN
θ value	3.61106e-41 (rank : 35)	NC score	0.477889 (rank : 206)
Query Neighborhood Hits	453	Target Neighborhood Hits	657	Shared Neighborhood Hits	346
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR3_HUMAN
θ value	2.58786e-39 (rank : 36)	NC score	0.476077 (rank : 208)
Query Neighborhood Hits	453	Target Neighborhood Hits	680	Shared Neighborhood Hits	324
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR1_HUMAN
θ value	4.41421e-39 (rank : 37)	NC score	0.459429 (rank : 217)
Query Neighborhood Hits	453	Target Neighborhood Hits	613	Shared Neighborhood Hits	310
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

DLK_HUMAN
θ value	1.6774e-38 (rank : 38)	NC score	0.941052 (rank : 18)
Query Neighborhood Hits	453	Target Neighborhood Hits	401	Shared Neighborhood Hits	352
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

LTBP3_HUMAN
θ value	4.13158e-37 (rank : 39)	NC score	0.845137 (rank : 31)
Query Neighborhood Hits	453	Target Neighborhood Hits	502	Shared Neighborhood Hits	345
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

CELR3_MOUSE
θ value	1.20211e-36 (rank : 40)	NC score	0.469444 (rank : 209)
Query Neighborhood Hits	453	Target Neighborhood Hits	687	Shared Neighborhood Hits	326
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

DLK_MOUSE
θ value	2.96089e-35 (rank : 41)	NC score	0.939703 (rank : 19)
Query Neighborhood Hits	453	Target Neighborhood Hits	374	Shared Neighborhood Hits	340
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

FBN1_MOUSE
θ value	2.96089e-35 (rank : 42)	NC score	0.844062 (rank : 33)
Query Neighborhood Hits	453	Target Neighborhood Hits	563	Shared Neighborhood Hits	374
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN3_HUMAN
θ value	2.96089e-35 (rank : 43)	NC score	0.849323 (rank : 28)
Query Neighborhood Hits	453	Target Neighborhood Hits	543	Shared Neighborhood Hits	370
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

CELR2_MOUSE
θ value	5.0505e-35 (rank : 44)	NC score	0.441304 (rank : 228)
Query Neighborhood Hits	453	Target Neighborhood Hits	584	Shared Neighborhood Hits	305
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

FBN1_HUMAN
θ value	1.46948e-34 (rank : 45)	NC score	0.843375 (rank : 34)
Query Neighborhood Hits	453	Target Neighborhood Hits	557	Shared Neighborhood Hits	374
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

LTBP3_MOUSE
θ value	4.72714e-33 (rank : 46)	NC score	0.838900 (rank : 41)
Query Neighborhood Hits	453	Target Neighborhood Hits	475	Shared Neighborhood Hits	338
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP2_HUMAN
θ value	1.79631e-32 (rank : 47)	NC score	0.845466 (rank : 30)
Query Neighborhood Hits	453	Target Neighborhood Hits	552	Shared Neighborhood Hits	360
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MEGF6_HUMAN
θ value	1.79631e-32 (rank : 48)	NC score	0.873833 (rank : 21)
Query Neighborhood Hits	453	Target Neighborhood Hits	671	Shared Neighborhood Hits	400
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

CELR1_MOUSE
θ value	3.06405e-32 (rank : 49)	NC score	0.459925 (rank : 216)
Query Neighborhood Hits	453	Target Neighborhood Hits	617	Shared Neighborhood Hits	308
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

FATH_HUMAN
θ value	4.00176e-32 (rank : 50)	NC score	0.511277 (rank : 186)
Query Neighborhood Hits	453	Target Neighborhood Hits	570	Shared Neighborhood Hits	335
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FBN2_HUMAN
θ value	4.00176e-32 (rank : 51)	NC score	0.841917 (rank : 38)
Query Neighborhood Hits	453	Target Neighborhood Hits	560	Shared Neighborhood Hits	378
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	4.00176e-32 (rank : 52)	NC score	0.843314 (rank : 35)
Query Neighborhood Hits	453	Target Neighborhood Hits	549	Shared Neighborhood Hits	376
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBLN2_HUMAN
θ value	6.82597e-32 (rank : 53)	NC score	0.810268 (rank : 48)
Query Neighborhood Hits	453	Target Neighborhood Hits	392	Shared Neighborhood Hits	269
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

LTBP2_MOUSE
θ value	1.28732e-30 (rank : 54)	NC score	0.846120 (rank : 29)
Query Neighborhood Hits	453	Target Neighborhood Hits	617	Shared Neighborhood Hits	354
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTB1L_MOUSE
θ value	1.85889e-29 (rank : 55)	NC score	0.825587 (rank : 44)
Query Neighborhood Hits	453	Target Neighborhood Hits	514	Shared Neighborhood Hits	356
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	1.85889e-29 (rank : 56)	NC score	0.825099 (rank : 45)
Query Neighborhood Hits	453	Target Neighborhood Hits	479	Shared Neighborhood Hits	340
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

TENX_HUMAN
θ value	3.50572e-28 (rank : 57)	NC score	0.657996 (rank : 117)
Query Neighborhood Hits	453	Target Neighborhood Hits	789	Shared Neighborhood Hits	335
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

FBLN1_HUMAN
θ value	7.80994e-28 (rank : 58)	NC score	0.798338 (rank : 56)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	273
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	1.33217e-27 (rank : 59)	NC score	0.798832 (rank : 55)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	269
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

LTB1L_HUMAN
θ value	2.96777e-27 (rank : 60)	NC score	0.823126 (rank : 46)
Query Neighborhood Hits	453	Target Neighborhood Hits	553	Shared Neighborhood Hits	344
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	2.96777e-27 (rank : 61)	NC score	0.822671 (rank : 47)
Query Neighborhood Hits	453	Target Neighborhood Hits	502	Shared Neighborhood Hits	343
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NELL2_MOUSE
θ value	1.12775e-26 (rank : 62)	NC score	0.840538 (rank : 39)
Query Neighborhood Hits	453	Target Neighborhood Hits	436	Shared Neighborhood Hits	335
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NELL2_HUMAN
θ value	4.28545e-26 (rank : 63)	NC score	0.838670 (rank : 42)
Query Neighborhood Hits	453	Target Neighborhood Hits	449	Shared Neighborhood Hits	335
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

SREC2_HUMAN
θ value	1.80048e-24 (rank : 64)	NC score	0.790987 (rank : 60)
Query Neighborhood Hits	453	Target Neighborhood Hits	645	Shared Neighborhood Hits	318
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

HMCN1_HUMAN
θ value	1.5242e-23 (rank : 65)	NC score	0.480282 (rank : 205)
Query Neighborhood Hits	453	Target Neighborhood Hits	983	Shared Neighborhood Hits	290
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

FBLN2_MOUSE
θ value	2.59989e-23 (rank : 66)	NC score	0.801603 (rank : 53)
Query Neighborhood Hits	453	Target Neighborhood Hits	505	Shared Neighborhood Hits	282
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

TENA_HUMAN
θ value	3.39556e-23 (rank : 67)	NC score	0.659855 (rank : 116)
Query Neighborhood Hits	453	Target Neighborhood Hits	631	Shared Neighborhood Hits	334
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	4.43474e-23 (rank : 68)	NC score	0.654499 (rank : 119)
Query Neighborhood Hits	453	Target Neighborhood Hits	596	Shared Neighborhood Hits	323
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

SREC2_MOUSE
θ value	9.87957e-23 (rank : 69)	NC score	0.796991 (rank : 57)
Query Neighborhood Hits	453	Target Neighborhood Hits	605	Shared Neighborhood Hits	320
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

NELL1_HUMAN
θ value	1.29031e-22 (rank : 70)	NC score	0.843056 (rank : 37)
Query Neighborhood Hits	453	Target Neighborhood Hits	451	Shared Neighborhood Hits	333
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

SREC_HUMAN
θ value	1.09232e-21 (rank : 71)	NC score	0.801986 (rank : 52)
Query Neighborhood Hits	453	Target Neighborhood Hits	645	Shared Neighborhood Hits	341
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

PGBM_HUMAN
θ value	1.86321e-21 (rank : 72)	NC score	0.492529 (rank : 198)
Query Neighborhood Hits	453	Target Neighborhood Hits	1113	Shared Neighborhood Hits	355
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

C1QR1_MOUSE
θ value	1.5773e-20 (rank : 73)	NC score	0.807366 (rank : 50)
Query Neighborhood Hits	453	Target Neighborhood Hits	342	Shared Neighborhood Hits	277
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CSPG3_MOUSE
θ value	1.5773e-20 (rank : 74)	NC score	0.594115 (rank : 138)
Query Neighborhood Hits	453	Target Neighborhood Hits	657	Shared Neighborhood Hits	276
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

EDIL3_HUMAN
θ value	1.5773e-20 (rank : 75)	NC score	0.728405 (rank : 85)
Query Neighborhood Hits	453	Target Neighborhood Hits	292	Shared Neighborhood Hits	259
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	2.06002e-20 (rank : 76)	NC score	0.738718 (rank : 83)
Query Neighborhood Hits	453	Target Neighborhood Hits	317	Shared Neighborhood Hits	279
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

LRP1B_HUMAN
θ value	4.58923e-20 (rank : 77)	NC score	0.669151 (rank : 111)
Query Neighborhood Hits	453	Target Neighborhood Hits	602	Shared Neighborhood Hits	384
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	4.58923e-20 (rank : 78)	NC score	0.674543 (rank : 109)
Query Neighborhood Hits	453	Target Neighborhood Hits	617	Shared Neighborhood Hits	381
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

PROS_HUMAN
θ value	5.99374e-20 (rank : 79)	NC score	0.796101 (rank : 58)
Query Neighborhood Hits	453	Target Neighborhood Hits	340	Shared Neighborhood Hits	297
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

CSPG3_HUMAN
θ value	7.82807e-20 (rank : 80)	NC score	0.585399 (rank : 144)
Query Neighborhood Hits	453	Target Neighborhood Hits	676	Shared Neighborhood Hits	264
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LAMA1_HUMAN
θ value	7.82807e-20 (rank : 81)	NC score	0.620394 (rank : 126)
Query Neighborhood Hits	453	Target Neighborhood Hits	804	Shared Neighborhood Hits	308
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

SCUB3_HUMAN
θ value	1.02238e-19 (rank : 82)	NC score	0.782331 (rank : 62)
Query Neighborhood Hits	453	Target Neighborhood Hits	428	Shared Neighborhood Hits	279
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

FBLN4_HUMAN
θ value	1.74391e-19 (rank : 83)	NC score	0.781083 (rank : 64)
Query Neighborhood Hits	453	Target Neighborhood Hits	278	Shared Neighborhood Hits	242
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

SCUB3_MOUSE
θ value	1.74391e-19 (rank : 84)	NC score	0.780286 (rank : 65)
Query Neighborhood Hits	453	Target Neighborhood Hits	442	Shared Neighborhood Hits	282
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

EMR1_MOUSE
θ value	2.27762e-19 (rank : 85)	NC score	0.664883 (rank : 113)
Query Neighborhood Hits	453	Target Neighborhood Hits	349	Shared Neighborhood Hits	240
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

LAMA5_HUMAN
θ value	2.27762e-19 (rank : 86)	NC score	0.637617 (rank : 122)
Query Neighborhood Hits	453	Target Neighborhood Hits	976	Shared Neighborhood Hits	334
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

TSP4_HUMAN
θ value	3.88503e-19 (rank : 87)	NC score	0.722370 (rank : 91)
Query Neighborhood Hits	453	Target Neighborhood Hits	277	Shared Neighborhood Hits	248
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	3.88503e-19 (rank : 88)	NC score	0.724523 (rank : 88)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	250
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

EMR1_HUMAN
θ value	5.07402e-19 (rank : 89)	NC score	0.696983 (rank : 100)
Query Neighborhood Hits	453	Target Neighborhood Hits	382	Shared Neighborhood Hits	263
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

FBLN4_MOUSE
θ value	5.07402e-19 (rank : 90)	NC score	0.774634 (rank : 68)
Query Neighborhood Hits	453	Target Neighborhood Hits	270	Shared Neighborhood Hits	235
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

LRP1B_MOUSE
θ value	1.47631e-18 (rank : 91)	NC score	0.665940 (rank : 112)
Query Neighborhood Hits	453	Target Neighborhood Hits	606	Shared Neighborhood Hits	386
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

CSPG2_MOUSE
θ value	1.92812e-18 (rank : 92)	NC score	0.598952 (rank : 134)
Query Neighborhood Hits	453	Target Neighborhood Hits	711	Shared Neighborhood Hits	281
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

LAMB2_HUMAN
θ value	1.92812e-18 (rank : 93)	NC score	0.619492 (rank : 127)
Query Neighborhood Hits	453	Target Neighborhood Hits	692	Shared Neighborhood Hits	285
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

STAB1_MOUSE
θ value	1.92812e-18 (rank : 94)	NC score	0.778451 (rank : 67)
Query Neighborhood Hits	453	Target Neighborhood Hits	566	Shared Neighborhood Hits	351
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

GAS6_HUMAN
θ value	2.5182e-18 (rank : 95)	NC score	0.800304 (rank : 54)
Query Neighborhood Hits	453	Target Neighborhood Hits	348	Shared Neighborhood Hits	292
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

AGRIN_HUMAN
θ value	3.28887e-18 (rank : 96)	NC score	0.743997 (rank : 81)
Query Neighborhood Hits	453	Target Neighborhood Hits	582	Shared Neighborhood Hits	341
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

CSPG2_HUMAN
θ value	4.29542e-18 (rank : 97)	NC score	0.594813 (rank : 137)
Query Neighborhood Hits	453	Target Neighborhood Hits	681	Shared Neighborhood Hits	282
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

FBLN3_HUMAN
θ value	3.63628e-17 (rank : 98)	NC score	0.761475 (rank : 76)
Query Neighborhood Hits	453	Target Neighborhood Hits	293	Shared Neighborhood Hits	249
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

C1QR1_HUMAN
θ value	8.10077e-17 (rank : 99)	NC score	0.807693 (rank : 49)
Query Neighborhood Hits	453	Target Neighborhood Hits	493	Shared Neighborhood Hits	292
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

GAS6_MOUSE
θ value	1.058e-16 (rank : 100)	NC score	0.803674 (rank : 51)
Query Neighborhood Hits	453	Target Neighborhood Hits	343	Shared Neighborhood Hits	296
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

PGBM_MOUSE
θ value	1.058e-16 (rank : 101)	NC score	0.496664 (rank : 193)
Query Neighborhood Hits	453	Target Neighborhood Hits	1073	Shared Neighborhood Hits	346
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

HABP2_MOUSE
θ value	1.38178e-16 (rank : 102)	NC score	0.410068 (rank : 238)
Query Neighborhood Hits	453	Target Neighborhood Hits	445	Shared Neighborhood Hits	271
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LAMA5_MOUSE
θ value	1.38178e-16 (rank : 103)	NC score	0.652284 (rank : 120)
Query Neighborhood Hits	453	Target Neighborhood Hits	828	Shared Neighborhood Hits	333
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB2_MOUSE
θ value	1.80466e-16 (rank : 104)	NC score	0.611008 (rank : 129)
Query Neighborhood Hits	453	Target Neighborhood Hits	722	Shared Neighborhood Hits	283
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

WIF1_HUMAN
θ value	1.80466e-16 (rank : 105)	NC score	0.839901 (rank : 40)
Query Neighborhood Hits	453	Target Neighborhood Hits	392	Shared Neighborhood Hits	327
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

FBLN5_MOUSE
θ value	5.25075e-16 (rank : 106)	NC score	0.767486 (rank : 73)
Query Neighborhood Hits	453	Target Neighborhood Hits	317	Shared Neighborhood Hits	257
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

LAMA1_MOUSE
θ value	5.25075e-16 (rank : 107)	NC score	0.618940 (rank : 128)
Query Neighborhood Hits	453	Target Neighborhood Hits	838	Shared Neighborhood Hits	313
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	6.85773e-16 (rank : 108)	NC score	0.577136 (rank : 146)
Query Neighborhood Hits	453	Target Neighborhood Hits	1092	Shared Neighborhood Hits	300
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

WIF1_MOUSE
θ value	6.85773e-16 (rank : 109)	NC score	0.834280 (rank : 43)
Query Neighborhood Hits	453	Target Neighborhood Hits	393	Shared Neighborhood Hits	322
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

FBLN5_HUMAN
θ value	8.95645e-16 (rank : 110)	NC score	0.771162 (rank : 71)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	272
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

LAMB1_MOUSE
θ value	1.16975e-15 (rank : 111)	NC score	0.570683 (rank : 154)
Query Neighborhood Hits	453	Target Neighborhood Hits	919	Shared Neighborhood Hits	274
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

STAB1_HUMAN
θ value	1.16975e-15 (rank : 112)	NC score	0.781998 (rank : 63)
Query Neighborhood Hits	453	Target Neighborhood Hits	546	Shared Neighborhood Hits	350
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

NID2_MOUSE
θ value	1.99529e-15 (rank : 113)	NC score	0.727099 (rank : 87)
Query Neighborhood Hits	453	Target Neighborhood Hits	338	Shared Neighborhood Hits	269
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

CD97_HUMAN
θ value	2.60593e-15 (rank : 114)	NC score	0.663006 (rank : 115)
Query Neighborhood Hits	453	Target Neighborhood Hits	353	Shared Neighborhood Hits	252
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

EMR2_HUMAN
θ value	2.60593e-15 (rank : 115)	NC score	0.672271 (rank : 110)
Query Neighborhood Hits	453	Target Neighborhood Hits	345	Shared Neighborhood Hits	250
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

LAMB1_HUMAN
θ value	3.40345e-15 (rank : 116)	NC score	0.550538 (rank : 167)
Query Neighborhood Hits	453	Target Neighborhood Hits	1018	Shared Neighborhood Hits	288
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

PROS_MOUSE
θ value	3.40345e-15 (rank : 117)	NC score	0.791057 (rank : 59)
Query Neighborhood Hits	453	Target Neighborhood Hits	330	Shared Neighborhood Hits	294
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

MATN2_HUMAN
θ value	4.44505e-15 (rank : 118)	NC score	0.693987 (rank : 102)
Query Neighborhood Hits	453	Target Neighborhood Hits	365	Shared Neighborhood Hits	254
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

HABP2_HUMAN
θ value	5.8054e-15 (rank : 119)	NC score	0.409663 (rank : 240)
Query Neighborhood Hits	453	Target Neighborhood Hits	431	Shared Neighborhood Hits	262
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

FAT2_HUMAN
θ value	9.90251e-15 (rank : 120)	NC score	0.345313 (rank : 276)
Query Neighborhood Hits	453	Target Neighborhood Hits	507	Shared Neighborhood Hits	239
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

NID1_MOUSE
θ value	9.90251e-15 (rank : 121)	NC score	0.716614 (rank : 95)
Query Neighborhood Hits	453	Target Neighborhood Hits	335	Shared Neighborhood Hits	262
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

LAMA2_MOUSE
θ value	1.68911e-14 (rank : 122)	NC score	0.548354 (rank : 168)
Query Neighborhood Hits	453	Target Neighborhood Hits	1198	Shared Neighborhood Hits	310
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

FBLN3_MOUSE
θ value	2.20605e-14 (rank : 123)	NC score	0.752965 (rank : 78)
Query Neighborhood Hits	453	Target Neighborhood Hits	279	Shared Neighborhood Hits	237
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

STAB2_MOUSE
θ value	2.88119e-14 (rank : 124)	NC score	0.778586 (rank : 66)
Query Neighborhood Hits	453	Target Neighborhood Hits	528	Shared Neighborhood Hits	349
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

EGF_MOUSE
θ value	3.76295e-14 (rank : 125)	NC score	0.722531 (rank : 90)
Query Neighborhood Hits	453	Target Neighborhood Hits	358	Shared Neighborhood Hits	299
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

TSP3_MOUSE
θ value	8.38298e-14 (rank : 126)	NC score	0.655964 (rank : 118)
Query Neighborhood Hits	453	Target Neighborhood Hits	247	Shared Neighborhood Hits	218
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

MATN2_MOUSE
θ value	1.42992e-13 (rank : 127)	NC score	0.680467 (rank : 106)
Query Neighborhood Hits	453	Target Neighborhood Hits	356	Shared Neighborhood Hits	249
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

STAB2_HUMAN
θ value	1.86753e-13 (rank : 128)	NC score	0.782546 (rank : 61)
Query Neighborhood Hits	453	Target Neighborhood Hits	534	Shared Neighborhood Hits	346
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

NID1_HUMAN
θ value	4.16044e-13 (rank : 129)	NC score	0.716614 (rank : 94)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	270
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TRBM_HUMAN
θ value	7.09661e-13 (rank : 130)	NC score	0.766073 (rank : 74)
Query Neighborhood Hits	453	Target Neighborhood Hits	339	Shared Neighborhood Hits	263
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

NID2_HUMAN
θ value	9.26847e-13 (rank : 131)	NC score	0.728318 (rank : 86)
Query Neighborhood Hits	453	Target Neighborhood Hits	456	Shared Neighborhood Hits	278
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

TSP3_HUMAN
θ value	9.26847e-13 (rank : 132)	NC score	0.646575 (rank : 121)
Query Neighborhood Hits	453	Target Neighborhood Hits	250	Shared Neighborhood Hits	213
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

HGFA_HUMAN
θ value	2.0648e-12 (rank : 133)	NC score	0.318859 (rank : 293)
Query Neighborhood Hits	453	Target Neighborhood Hits	436	Shared Neighborhood Hits	234
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_MOUSE
θ value	2.0648e-12 (rank : 134)	NC score	0.313381 (rank : 298)
Query Neighborhood Hits	453	Target Neighborhood Hits	419	Shared Neighborhood Hits	237
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

LDLR_HUMAN
θ value	3.52202e-12 (rank : 135)	NC score	0.571980 (rank : 150)
Query Neighborhood Hits	453	Target Neighborhood Hits	375	Shared Neighborhood Hits	284
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

UROM_HUMAN
θ value	4.59992e-12 (rank : 136)	NC score	0.732900 (rank : 84)
Query Neighborhood Hits	453	Target Neighborhood Hits	284	Shared Neighborhood Hits	249
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

VLDLR_MOUSE
θ value	4.59992e-12 (rank : 137)	NC score	0.563815 (rank : 161)
Query Neighborhood Hits	453	Target Neighborhood Hits	360	Shared Neighborhood Hits	262
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

EGF_HUMAN
θ value	7.84624e-12 (rank : 138)	NC score	0.685245 (rank : 105)
Query Neighborhood Hits	453	Target Neighborhood Hits	343	Shared Neighborhood Hits	280
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

VLDLR_HUMAN
θ value	7.84624e-12 (rank : 139)	NC score	0.564769 (rank : 160)
Query Neighborhood Hits	453	Target Neighborhood Hits	383	Shared Neighborhood Hits	269
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

COMP_MOUSE
θ value	1.74796e-11 (rank : 140)	NC score	0.691947 (rank : 103)
Query Neighborhood Hits	453	Target Neighborhood Hits	290	Shared Neighborhood Hits	243
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

MEGF8_MOUSE
θ value	3.89403e-11 (rank : 141)	NC score	0.704210 (rank : 98)
Query Neighborhood Hits	453	Target Neighborhood Hits	520	Shared Neighborhood Hits	318
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_HUMAN
θ value	5.08577e-11 (rank : 142)	NC score	0.709505 (rank : 96)
Query Neighborhood Hits	453	Target Neighborhood Hits	528	Shared Neighborhood Hits	325
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

COMP_HUMAN
θ value	8.67504e-11 (rank : 143)	NC score	0.664059 (rank : 114)
Query Neighborhood Hits	453	Target Neighborhood Hits	258	Shared Neighborhood Hits	227
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CNTP3_HUMAN
θ value	1.133e-10 (rank : 144)	NC score	0.347106 (rank : 273)
Query Neighborhood Hits	453	Target Neighborhood Hits	195	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

ITB6_HUMAN
θ value	1.133e-10 (rank : 145)	NC score	0.519277 (rank : 183)
Query Neighborhood Hits	453	Target Neighborhood Hits	318	Shared Neighborhood Hits	240
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

TIE1_HUMAN
θ value	1.133e-10 (rank : 146)	NC score	0.234936 (rank : 345)
Query Neighborhood Hits	453	Target Neighborhood Hits	1241	Shared Neighborhood Hits	273
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
θ value	1.47974e-10 (rank : 147)	NC score	0.230760 (rank : 350)
Query Neighborhood Hits	453	Target Neighborhood Hits	1266	Shared Neighborhood Hits	270
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

LAMB3_MOUSE
θ value	5.62301e-10 (rank : 148)	NC score	0.552298 (rank : 165)
Query Neighborhood Hits	453	Target Neighborhood Hits	444	Shared Neighborhood Hits	228
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

CNTP4_HUMAN
θ value	1.25267e-09 (rank : 149)	NC score	0.352672 (rank : 268)
Query Neighborhood Hits	453	Target Neighborhood Hits	187	Shared Neighborhood Hits	128
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

EGFL8_MOUSE
θ value	1.25267e-09 (rank : 150)	NC score	0.758214 (rank : 77)
Query Neighborhood Hits	453	Target Neighborhood Hits	266	Shared Neighborhood Hits	246
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

LDLR_MOUSE
θ value	1.25267e-09 (rank : 151)	NC score	0.540232 (rank : 172)
Query Neighborhood Hits	453	Target Neighborhood Hits	382	Shared Neighborhood Hits	268
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

PROZ_HUMAN
θ value	1.25267e-09 (rank : 152)	NC score	0.595357 (rank : 135)
Query Neighborhood Hits	453	Target Neighborhood Hits	422	Shared Neighborhood Hits	265
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

UROM_MOUSE
θ value	1.25267e-09 (rank : 153)	NC score	0.718265 (rank : 93)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	245
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

LAMC3_HUMAN
θ value	1.63604e-09 (rank : 154)	NC score	0.595131 (rank : 136)
Query Neighborhood Hits	453	Target Neighborhood Hits	588	Shared Neighborhood Hits	289
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

TSP1_MOUSE
θ value	1.63604e-09 (rank : 155)	NC score	0.502615 (rank : 187)
Query Neighborhood Hits	453	Target Neighborhood Hits	396	Shared Neighborhood Hits	239
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

USH2A_HUMAN
θ value	1.63604e-09 (rank : 156)	NC score	0.498163 (rank : 190)
Query Neighborhood Hits	453	Target Neighborhood Hits	600	Shared Neighborhood Hits	252
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

ITB6_MOUSE
θ value	2.79066e-09 (rank : 157)	NC score	0.540980 (rank : 171)
Query Neighborhood Hits	453	Target Neighborhood Hits	341	Shared Neighborhood Hits	256
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

LAMC1_HUMAN
θ value	2.79066e-09 (rank : 158)	NC score	0.541042 (rank : 170)
Query Neighborhood Hits	453	Target Neighborhood Hits	922	Shared Neighborhood Hits	280
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

TRBM_MOUSE
θ value	2.79066e-09 (rank : 159)	NC score	0.750579 (rank : 79)
Query Neighborhood Hits	453	Target Neighborhood Hits	361	Shared Neighborhood Hits	267
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

ITB7_MOUSE
θ value	3.64472e-09 (rank : 160)	NC score	0.498710 (rank : 189)
Query Neighborhood Hits	453	Target Neighborhood Hits	277	Shared Neighborhood Hits	225
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

SUSD1_HUMAN
θ value	3.64472e-09 (rank : 161)	NC score	0.719784 (rank : 92)
Query Neighborhood Hits	453	Target Neighborhood Hits	285	Shared Neighborhood Hits	225
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

LAMB3_HUMAN
θ value	8.11959e-09 (rank : 162)	NC score	0.520059 (rank : 182)
Query Neighborhood Hits	453	Target Neighborhood Hits	461	Shared Neighborhood Hits	204
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMC3_MOUSE
θ value	8.11959e-09 (rank : 163)	NC score	0.602161 (rank : 131)
Query Neighborhood Hits	453	Target Neighborhood Hits	624	Shared Neighborhood Hits	286
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

USH2A_MOUSE
θ value	8.11959e-09 (rank : 164)	NC score	0.515176 (rank : 184)
Query Neighborhood Hits	453	Target Neighborhood Hits	626	Shared Neighborhood Hits	268
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

PROZ_MOUSE
θ value	1.06045e-08 (rank : 165)	NC score	0.600914 (rank : 132)
Query Neighborhood Hits	453	Target Neighborhood Hits	410	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

TSP1_HUMAN
θ value	1.06045e-08 (rank : 166)	NC score	0.497784 (rank : 191)
Query Neighborhood Hits	453	Target Neighborhood Hits	389	Shared Neighborhood Hits	235
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

ELTD1_MOUSE
θ value	1.38499e-08 (rank : 167)	NC score	0.571201 (rank : 152)
Query Neighborhood Hits	453	Target Neighborhood Hits	288	Shared Neighborhood Hits	206
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

CNTP1_HUMAN
θ value	1.80886e-08 (rank : 168)	NC score	0.327821 (rank : 284)
Query Neighborhood Hits	453	Target Neighborhood Hits	196	Shared Neighborhood Hits	124
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP4_MOUSE
θ value	2.36244e-08 (rank : 169)	NC score	0.358712 (rank : 266)
Query Neighborhood Hits	453	Target Neighborhood Hits	193	Shared Neighborhood Hits	148
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

LAMC1_MOUSE
θ value	2.36244e-08 (rank : 170)	NC score	0.556723 (rank : 164)
Query Neighborhood Hits	453	Target Neighborhood Hits	856	Shared Neighborhood Hits	276
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_HUMAN
θ value	2.36244e-08 (rank : 171)	NC score	0.567645 (rank : 156)
Query Neighborhood Hits	453	Target Neighborhood Hits	715	Shared Neighborhood Hits	266
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

CNTP1_MOUSE
θ value	3.08544e-08 (rank : 172)	NC score	0.320396 (rank : 291)
Query Neighborhood Hits	453	Target Neighborhood Hits	183	Shared Neighborhood Hits	118
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

FA12_HUMAN
θ value	5.26297e-08 (rank : 173)	NC score	0.289440 (rank : 312)
Query Neighborhood Hits	453	Target Neighborhood Hits	425	Shared Neighborhood Hits	228
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

PROC_HUMAN
θ value	5.26297e-08 (rank : 174)	NC score	0.296796 (rank : 307)
Query Neighborhood Hits	453	Target Neighborhood Hits	406	Shared Neighborhood Hits	245
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

LAMC2_MOUSE
θ value	6.87365e-08 (rank : 175)	NC score	0.590780 (rank : 141)
Query Neighborhood Hits	453	Target Neighborhood Hits	614	Shared Neighborhood Hits	274
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

NRX2A_HUMAN
θ value	6.87365e-08 (rank : 176)	NC score	0.356292 (rank : 267)
Query Neighborhood Hits	453	Target Neighborhood Hits	614	Shared Neighborhood Hits	147
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

FA9_HUMAN
θ value	8.97725e-08 (rank : 177)	NC score	0.336543 (rank : 281)
Query Neighborhood Hits	453	Target Neighborhood Hits	421	Shared Neighborhood Hits	251
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

PGCB_MOUSE
θ value	8.97725e-08 (rank : 178)	NC score	0.349796 (rank : 271)
Query Neighborhood Hits	453	Target Neighborhood Hits	459	Shared Neighborhood Hits	191
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

EGFL8_HUMAN
θ value	1.17247e-07 (rank : 179)	NC score	0.748691 (rank : 80)
Query Neighborhood Hits	453	Target Neighborhood Hits	270	Shared Neighborhood Hits	243
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL7_HUMAN
θ value	1.53129e-07 (rank : 180)	NC score	0.772530 (rank : 69)
Query Neighborhood Hits	453	Target Neighborhood Hits	325	Shared Neighborhood Hits	278
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

FA10_MOUSE
θ value	1.53129e-07 (rank : 181)	NC score	0.351675 (rank : 269)
Query Neighborhood Hits	453	Target Neighborhood Hits	435	Shared Neighborhood Hits	264
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

LAMA3_MOUSE
θ value	1.99992e-07 (rank : 182)	NC score	0.537932 (rank : 173)
Query Neighborhood Hits	453	Target Neighborhood Hits	859	Shared Neighborhood Hits	299
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

PROC_MOUSE
θ value	1.99992e-07 (rank : 183)	NC score	0.328109 (rank : 283)
Query Neighborhood Hits	453	Target Neighborhood Hits	426	Shared Neighborhood Hits	257
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

TSP2_HUMAN
θ value	2.61198e-07 (rank : 184)	NC score	0.457663 (rank : 219)
Query Neighborhood Hits	453	Target Neighborhood Hits	359	Shared Neighborhood Hits	215
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

ITB5_HUMAN
θ value	3.41135e-07 (rank : 185)	NC score	0.499372 (rank : 188)
Query Neighborhood Hits	453	Target Neighborhood Hits	310	Shared Neighborhood Hits	238
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB7_HUMAN
θ value	3.41135e-07 (rank : 186)	NC score	0.496857 (rank : 192)
Query Neighborhood Hits	453	Target Neighborhood Hits	290	Shared Neighborhood Hits	233
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

LAMA4_MOUSE
θ value	3.41135e-07 (rank : 187)	NC score	0.492077 (rank : 199)
Query Neighborhood Hits	453	Target Neighborhood Hits	584	Shared Neighborhood Hits	219
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

EGFL7_MOUSE
θ value	4.45536e-07 (rank : 188)	NC score	0.762273 (rank : 75)
Query Neighborhood Hits	453	Target Neighborhood Hits	287	Shared Neighborhood Hits	255
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

TSP2_MOUSE
θ value	5.81887e-07 (rank : 189)	NC score	0.448505 (rank : 224)
Query Neighborhood Hits	453	Target Neighborhood Hits	352	Shared Neighborhood Hits	217
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

CD97_MOUSE
θ value	7.59969e-07 (rank : 190)	NC score	0.573435 (rank : 149)
Query Neighborhood Hits	453	Target Neighborhood Hits	295	Shared Neighborhood Hits	210
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

LAMA4_HUMAN
θ value	7.59969e-07 (rank : 191)	NC score	0.467742 (rank : 212)
Query Neighborhood Hits	453	Target Neighborhood Hits	708	Shared Neighborhood Hits	219
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MFGM_MOUSE
θ value	7.59969e-07 (rank : 192)	NC score	0.535728 (rank : 174)
Query Neighborhood Hits	453	Target Neighborhood Hits	233	Shared Neighborhood Hits	205
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

FA7_HUMAN
θ value	9.92553e-07 (rank : 193)	NC score	0.319367 (rank : 292)
Query Neighborhood Hits	453	Target Neighborhood Hits	404	Shared Neighborhood Hits	238
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

ITB5_MOUSE
θ value	9.92553e-07 (rank : 194)	NC score	0.512974 (rank : 185)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	251
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

NRX3A_HUMAN
θ value	9.92553e-07 (rank : 195)	NC score	0.377188 (rank : 255)
Query Neighborhood Hits	453	Target Neighborhood Hits	164	Shared Neighborhood Hits	145
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

TENN_MOUSE
θ value	9.92553e-07 (rank : 196)	NC score	0.387068 (rank : 251)
Query Neighborhood Hits	453	Target Neighborhood Hits	484	Shared Neighborhood Hits	248
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

ZAN_MOUSE
θ value	9.92553e-07 (rank : 197)	NC score	0.591710 (rank : 140)
Query Neighborhood Hits	453	Target Neighborhood Hits	808	Shared Neighborhood Hits	350
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

FA7_MOUSE
θ value	1.29631e-06 (rank : 198)	NC score	0.281000 (rank : 318)
Query Neighborhood Hits	453	Target Neighborhood Hits	374	Shared Neighborhood Hits	213
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

PGCB_HUMAN
θ value	1.29631e-06 (rank : 199)	NC score	0.325467 (rank : 286)
Query Neighborhood Hits	453	Target Neighborhood Hits	478	Shared Neighborhood Hits	184
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

CNTP2_MOUSE
θ value	1.69304e-06 (rank : 200)	NC score	0.368433 (rank : 259)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	145
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CREL1_HUMAN
θ value	1.69304e-06 (rank : 201)	NC score	0.740944 (rank : 82)
Query Neighborhood Hits	453	Target Neighborhood Hits	441	Shared Neighborhood Hits	263
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

FA10_HUMAN
θ value	1.69304e-06 (rank : 202)	NC score	0.343554 (rank : 278)
Query Neighborhood Hits	453	Target Neighborhood Hits	431	Shared Neighborhood Hits	252
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

TENR_MOUSE
θ value	2.21117e-06 (rank : 203)	NC score	0.455223 (rank : 221)
Query Neighborhood Hits	453	Target Neighborhood Hits	531	Shared Neighborhood Hits	270
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

LRP8_HUMAN
θ value	2.88788e-06 (rank : 204)	NC score	0.534101 (rank : 175)
Query Neighborhood Hits	453	Target Neighborhood Hits	346	Shared Neighborhood Hits	247
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

ITB2_MOUSE
θ value	3.77169e-06 (rank : 205)	NC score	0.483770 (rank : 203)
Query Neighborhood Hits	453	Target Neighborhood Hits	326	Shared Neighborhood Hits	250
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

NRX1A_HUMAN
θ value	3.77169e-06 (rank : 206)	NC score	0.392742 (rank : 244)
Query Neighborhood Hits	453	Target Neighborhood Hits	170	Shared Neighborhood Hits	140
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	3.77169e-06 (rank : 207)	NC score	0.391662 (rank : 245)
Query Neighborhood Hits	453	Target Neighborhood Hits	164	Shared Neighborhood Hits	139
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

CD248_MOUSE
θ value	4.92598e-06 (rank : 208)	NC score	0.599191 (rank : 133)
Query Neighborhood Hits	453	Target Neighborhood Hits	578	Shared Neighborhood Hits	219
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CNTP2_HUMAN
θ value	4.92598e-06 (rank : 209)	NC score	0.364392 (rank : 261)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CREL1_MOUSE
θ value	4.92598e-06 (rank : 210)	NC score	0.724396 (rank : 89)
Query Neighborhood Hits	453	Target Neighborhood Hits	524	Shared Neighborhood Hits	260
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

MATN3_HUMAN
θ value	4.92598e-06 (rank : 211)	NC score	0.567254 (rank : 157)
Query Neighborhood Hits	453	Target Neighborhood Hits	268	Shared Neighborhood Hits	201
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

TENN_HUMAN
θ value	4.92598e-06 (rank : 212)	NC score	0.367212 (rank : 260)
Query Neighborhood Hits	453	Target Neighborhood Hits	453	Shared Neighborhood Hits	243
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

MATN3_MOUSE
θ value	6.43352e-06 (rank : 213)	NC score	0.570233 (rank : 155)
Query Neighborhood Hits	453	Target Neighborhood Hits	261	Shared Neighborhood Hits	205
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

NTNG1_MOUSE
θ value	1.09739e-05 (rank : 214)	NC score	0.523146 (rank : 178)
Query Neighborhood Hits	453	Target Neighborhood Hits	246	Shared Neighborhood Hits	211
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

TENR_HUMAN
θ value	1.09739e-05 (rank : 215)	NC score	0.447303 (rank : 226)
Query Neighborhood Hits	453	Target Neighborhood Hits	526	Shared Neighborhood Hits	267
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

ZAN_HUMAN
θ value	1.09739e-05 (rank : 216)	NC score	0.373762 (rank : 257)
Query Neighborhood Hits	453	Target Neighborhood Hits	679	Shared Neighborhood Hits	268
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ITB1_HUMAN
θ value	1.43324e-05 (rank : 217)	NC score	0.460284 (rank : 215)
Query Neighborhood Hits	453	Target Neighborhood Hits	298	Shared Neighborhood Hits	218
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

TIE2_MOUSE
θ value	1.43324e-05 (rank : 218)	NC score	0.200734 (rank : 369)
Query Neighborhood Hits	453	Target Neighborhood Hits	1204	Shared Neighborhood Hits	266
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

CD248_HUMAN
θ value	1.87187e-05 (rank : 219)	NC score	0.589628 (rank : 142)
Query Neighborhood Hits	453	Target Neighborhood Hits	679	Shared Neighborhood Hits	233
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

ITB4_HUMAN
θ value	2.44474e-05 (rank : 220)	NC score	0.462396 (rank : 214)
Query Neighborhood Hits	453	Target Neighborhood Hits	458	Shared Neighborhood Hits	242
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

CRUM3_HUMAN
θ value	3.19293e-05 (rank : 221)	NC score	0.122522 (rank : 466)
Query Neighborhood Hits	453	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BUF7, Q8N0V8, Q8WVA0	Gene names	CRB3
Domain Architecture	No domain graphic available
Description	Crumbs protein homolog 3 precursor.

GRN_MOUSE
θ value	4.1701e-05 (rank : 222)	NC score	0.496325 (rank : 194)
Query Neighborhood Hits	453	Target Neighborhood Hits	248	Shared Neighborhood Hits	174
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

KR106_HUMAN
θ value	4.1701e-05 (rank : 223)	NC score	0.564961 (rank : 159)
Query Neighborhood Hits	453	Target Neighborhood Hits	347	Shared Neighborhood Hits	218
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

LYAM2_MOUSE
θ value	4.1701e-05 (rank : 224)	NC score	0.390904 (rank : 247)
Query Neighborhood Hits	453	Target Neighborhood Hits	420	Shared Neighborhood Hits	261
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CRUM3_MOUSE
θ value	5.44631e-05 (rank : 225)	NC score	0.106858 (rank : 496)
Query Neighborhood Hits	453	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q8QZT4, Q3TJV6	Gene names	Crb3
Domain Architecture	No domain graphic available
Description	Crumbs protein homolog 3 precursor.

KR10A_HUMAN
θ value	5.44631e-05 (rank : 226)	NC score	0.320540 (rank : 290)
Query Neighborhood Hits	453	Target Neighborhood Hits	232	Shared Neighborhood Hits	146
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

LAMA3_HUMAN
θ value	5.44631e-05 (rank : 227)	NC score	0.477537 (rank : 207)
Query Neighborhood Hits	453	Target Neighborhood Hits	760	Shared Neighborhood Hits	250
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LRP2_HUMAN
θ value	5.44631e-05 (rank : 228)	NC score	0.570805 (rank : 153)
Query Neighborhood Hits	453	Target Neighborhood Hits	573	Shared Neighborhood Hits	370
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP8_MOUSE
θ value	5.44631e-05 (rank : 229)	NC score	0.551360 (rank : 166)
Query Neighborhood Hits	453	Target Neighborhood Hits	385	Shared Neighborhood Hits	273
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

TIE2_HUMAN
θ value	5.44631e-05 (rank : 230)	NC score	0.201919 (rank : 367)
Query Neighborhood Hits	453	Target Neighborhood Hits	1192	Shared Neighborhood Hits	259
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TPA_HUMAN
θ value	5.44631e-05 (rank : 231)	NC score	0.187811 (rank : 376)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	163
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

ADA19_MOUSE
θ value	9.29e-05 (rank : 232)	NC score	0.159489 (rank : 407)
Query Neighborhood Hits	453	Target Neighborhood Hits	315	Shared Neighborhood Hits	175
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ITB2_HUMAN
θ value	9.29e-05 (rank : 233)	NC score	0.468759 (rank : 211)
Query Neighborhood Hits	453	Target Neighborhood Hits	282	Shared Neighborhood Hits	219
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

SSPO_MOUSE
θ value	0.000121331 (rank : 234)	NC score	0.400277 (rank : 242)
Query Neighborhood Hits	453	Target Neighborhood Hits	800	Shared Neighborhood Hits	314
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ITB8_HUMAN
θ value	0.00020696 (rank : 235)	NC score	0.400226 (rank : 243)
Query Neighborhood Hits	453	Target Neighborhood Hits	280	Shared Neighborhood Hits	220
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KR107_HUMAN
θ value	0.00020696 (rank : 236)	NC score	0.574110 (rank : 148)
Query Neighborhood Hits	453	Target Neighborhood Hits	330	Shared Neighborhood Hits	211
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

LYAM3_MOUSE
θ value	0.00020696 (rank : 237)	NC score	0.408350 (rank : 241)
Query Neighborhood Hits	453	Target Neighborhood Hits	390	Shared Neighborhood Hits	249
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MATN4_HUMAN
θ value	0.00020696 (rank : 238)	NC score	0.571250 (rank : 151)
Query Neighborhood Hits	453	Target Neighborhood Hits	287	Shared Neighborhood Hits	220
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MEGF9_HUMAN
θ value	0.00020696 (rank : 239)	NC score	0.623267 (rank : 123)
Query Neighborhood Hits	453	Target Neighborhood Hits	557	Shared Neighborhood Hits	267
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PGCA_HUMAN
θ value	0.00020696 (rank : 240)	NC score	0.250858 (rank : 332)
Query Neighborhood Hits	453	Target Neighborhood Hits	821	Shared Neighborhood Hits	177
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

LRP4_HUMAN
θ value	0.000270298 (rank : 241)	NC score	0.491789 (rank : 200)
Query Neighborhood Hits	453	Target Neighborhood Hits	355	Shared Neighborhood Hits	258
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

NTNG1_HUMAN
θ value	0.00035302 (rank : 242)	NC score	0.520082 (rank : 181)
Query Neighborhood Hits	453	Target Neighborhood Hits	247	Shared Neighborhood Hits	208
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

TPA_MOUSE
θ value	0.00035302 (rank : 243)	NC score	0.187710 (rank : 377)
Query Neighborhood Hits	453	Target Neighborhood Hits	335	Shared Neighborhood Hits	169
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

VASN_HUMAN
θ value	0.000786445 (rank : 244)	NC score	0.193909 (rank : 371)
Query Neighborhood Hits	453	Target Neighborhood Hits	449	Shared Neighborhood Hits	140
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ELTD1_HUMAN
θ value	0.00102713 (rank : 245)	NC score	0.439103 (rank : 229)
Query Neighborhood Hits	453	Target Neighborhood Hits	269	Shared Neighborhood Hits	182
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ITB1_MOUSE
θ value	0.00102713 (rank : 246)	NC score	0.469188 (rank : 210)
Query Neighborhood Hits	453	Target Neighborhood Hits	283	Shared Neighborhood Hits	212
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

NAGPA_HUMAN
θ value	0.00102713 (rank : 247)	NC score	0.603373 (rank : 130)
Query Neighborhood Hits	453	Target Neighborhood Hits	282	Shared Neighborhood Hits	225
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

VWF_MOUSE
θ value	0.00102713 (rank : 248)	NC score	0.257153 (rank : 326)
Query Neighborhood Hits	453	Target Neighborhood Hits	381	Shared Neighborhood Hits	182
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ADAM8_MOUSE
θ value	0.00134147 (rank : 249)	NC score	0.190902 (rank : 374)
Query Neighborhood Hits	453	Target Neighborhood Hits	326	Shared Neighborhood Hits	173
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

TDGF1_MOUSE
θ value	0.00134147 (rank : 250)	NC score	0.432963 (rank : 230)
Query Neighborhood Hits	453	Target Neighborhood Hits	146	Shared Neighborhood Hits	143
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

GRN_HUMAN
θ value	0.00175202 (rank : 251)	NC score	0.490491 (rank : 201)
Query Neighborhood Hits	453	Target Neighborhood Hits	268	Shared Neighborhood Hits	178
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

NAGPA_MOUSE
θ value	0.00175202 (rank : 252)	NC score	0.592108 (rank : 139)
Query Neighborhood Hits	453	Target Neighborhood Hits	308	Shared Neighborhood Hits	247
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

KR101_HUMAN
θ value	0.00228821 (rank : 253)	NC score	0.493154 (rank : 197)
Query Neighborhood Hits	453	Target Neighborhood Hits	261	Shared Neighborhood Hits	171
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

LYAM2_HUMAN
θ value	0.00228821 (rank : 254)	NC score	0.387994 (rank : 250)
Query Neighborhood Hits	453	Target Neighborhood Hits	394	Shared Neighborhood Hits	250
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

KR102_HUMAN
θ value	0.00298849 (rank : 255)	NC score	0.458651 (rank : 218)
Query Neighborhood Hits	453	Target Neighborhood Hits	264	Shared Neighborhood Hits	169
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR105_HUMAN
θ value	0.00298849 (rank : 256)	NC score	0.441463 (rank : 227)
Query Neighborhood Hits	453	Target Neighborhood Hits	271	Shared Neighborhood Hits	175
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

MMRN1_HUMAN
θ value	0.00298849 (rank : 257)	NC score	0.284104 (rank : 317)
Query Neighborhood Hits	453	Target Neighborhood Hits	636	Shared Neighborhood Hits	159
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

HHIP_MOUSE
θ value	0.00390308 (rank : 258)	NC score	0.560602 (rank : 162)
Query Neighborhood Hits	453	Target Neighborhood Hits	219	Shared Neighborhood Hits	187
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ITB3_HUMAN
θ value	0.00390308 (rank : 259)	NC score	0.488747 (rank : 202)
Query Neighborhood Hits	453	Target Neighborhood Hits	325	Shared Neighborhood Hits	250
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

MUC5B_HUMAN
θ value	0.00390308 (rank : 260)	NC score	0.294453 (rank : 308)
Query Neighborhood Hits	453	Target Neighborhood Hits	1020	Shared Neighborhood Hits	251
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NTNG2_HUMAN
θ value	0.00390308 (rank : 261)	NC score	0.546775 (rank : 169)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	243
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

ATRN_MOUSE
θ value	0.00509761 (rank : 262)	NC score	0.448917 (rank : 223)
Query Neighborhood Hits	453	Target Neighborhood Hits	519	Shared Neighborhood Hits	269
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

HHIP_HUMAN
θ value	0.00509761 (rank : 263)	NC score	0.574963 (rank : 147)
Query Neighborhood Hits	453	Target Neighborhood Hits	249	Shared Neighborhood Hits	205
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KR10C_HUMAN
θ value	0.00509761 (rank : 264)	NC score	0.409841 (rank : 239)
Query Neighborhood Hits	453	Target Neighborhood Hits	219	Shared Neighborhood Hits	154
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

PERT_HUMAN
θ value	0.00509761 (rank : 265)	NC score	0.315612 (rank : 296)
Query Neighborhood Hits	453	Target Neighborhood Hits	221	Shared Neighborhood Hits	165
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

ATRN_HUMAN
θ value	0.00665767 (rank : 266)	NC score	0.448216 (rank : 225)
Query Neighborhood Hits	453	Target Neighborhood Hits	525	Shared Neighborhood Hits	272
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

KRA51_HUMAN
θ value	0.00665767 (rank : 267)	NC score	0.622972 (rank : 125)
Query Neighborhood Hits	453	Target Neighborhood Hits	288	Shared Neighborhood Hits	199
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LYAM3_HUMAN
θ value	0.00665767 (rank : 268)	NC score	0.361395 (rank : 264)
Query Neighborhood Hits	453	Target Neighborhood Hits	378	Shared Neighborhood Hits	228
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MFGM_HUMAN
θ value	0.00665767 (rank : 269)	NC score	0.304423 (rank : 303)
Query Neighborhood Hits	453	Target Neighborhood Hits	150	Shared Neighborhood Hits	128
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

ADA11_MOUSE
θ value	0.00869519 (rank : 270)	NC score	0.177256 (rank : 390)
Query Neighborhood Hits	453	Target Neighborhood Hits	263	Shared Neighborhood Hits	167
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA33_HUMAN
θ value	0.00869519 (rank : 271)	NC score	0.144022 (rank : 425)
Query Neighborhood Hits	453	Target Neighborhood Hits	264	Shared Neighborhood Hits	152
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

LRP4_MOUSE
θ value	0.00869519 (rank : 272)	NC score	0.494832 (rank : 196)
Query Neighborhood Hits	453	Target Neighborhood Hits	351	Shared Neighborhood Hits	256
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LYAM1_MOUSE
θ value	0.00869519 (rank : 273)	NC score	0.324635 (rank : 287)
Query Neighborhood Hits	453	Target Neighborhood Hits	332	Shared Neighborhood Hits	197
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

ADA11_HUMAN
θ value	0.0113563 (rank : 274)	NC score	0.178848 (rank : 388)
Query Neighborhood Hits	453	Target Neighborhood Hits	259	Shared Neighborhood Hits	166
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

CO7_HUMAN
θ value	0.0113563 (rank : 275)	NC score	0.214722 (rank : 356)
Query Neighborhood Hits	453	Target Neighborhood Hits	278	Shared Neighborhood Hits	133
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

UROK_MOUSE
θ value	0.0113563 (rank : 276)	NC score	0.112181 (rank : 484)
Query Neighborhood Hits	453	Target Neighborhood Hits	273	Shared Neighborhood Hits	120
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

NET1_HUMAN
θ value	0.0148317 (rank : 277)	NC score	0.344252 (rank : 277)
Query Neighborhood Hits	453	Target Neighborhood Hits	149	Shared Neighborhood Hits	118
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
θ value	0.0148317 (rank : 278)	NC score	0.338296 (rank : 280)
Query Neighborhood Hits	453	Target Neighborhood Hits	151	Shared Neighborhood Hits	116
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NTNG2_MOUSE
θ value	0.0148317 (rank : 279)	NC score	0.557237 (rank : 163)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	240
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

VASN_MOUSE
θ value	0.0148317 (rank : 280)	NC score	0.177625 (rank : 389)
Query Neighborhood Hits	453	Target Neighborhood Hits	426	Shared Neighborhood Hits	129
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ADA15_MOUSE
θ value	0.0193708 (rank : 281)	NC score	0.168743 (rank : 393)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	194
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

LYAM1_HUMAN
θ value	0.0193708 (rank : 282)	NC score	0.321182 (rank : 289)
Query Neighborhood Hits	453	Target Neighborhood Hits	315	Shared Neighborhood Hits	194
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MEGF9_MOUSE
θ value	0.0193708 (rank : 283)	NC score	0.579767 (rank : 145)
Query Neighborhood Hits	453	Target Neighborhood Hits	896	Shared Neighborhood Hits	239
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NET2_MOUSE
θ value	0.0252991 (rank : 284)	NC score	0.391474 (rank : 246)
Query Neighborhood Hits	453	Target Neighborhood Hits	193	Shared Neighborhood Hits	154
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

PCSK5_MOUSE
θ value	0.0252991 (rank : 285)	NC score	0.428799 (rank : 232)
Query Neighborhood Hits	453	Target Neighborhood Hits	613	Shared Neighborhood Hits	289
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

KR108_HUMAN
θ value	0.0330416 (rank : 286)	NC score	0.412228 (rank : 237)
Query Neighborhood Hits	453	Target Neighborhood Hits	226	Shared Neighborhood Hits	149
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

FSTL3_HUMAN
θ value	0.0431538 (rank : 287)	NC score	0.183033 (rank : 382)
Query Neighborhood Hits	453	Target Neighborhood Hits	162	Shared Neighborhood Hits	89
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

KR104_HUMAN
θ value	0.0431538 (rank : 288)	NC score	0.566150 (rank : 158)
Query Neighborhood Hits	453	Target Neighborhood Hits	313	Shared Neighborhood Hits	207
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

NET2_HUMAN
θ value	0.0431538 (rank : 289)	NC score	0.386207 (rank : 252)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	151
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

ADA19_HUMAN
θ value	0.0563607 (rank : 290)	NC score	0.152835 (rank : 412)
Query Neighborhood Hits	453	Target Neighborhood Hits	381	Shared Neighborhood Hits	164
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADAM8_HUMAN
θ value	0.0563607 (rank : 291)	NC score	0.169663 (rank : 392)
Query Neighborhood Hits	453	Target Neighborhood Hits	327	Shared Neighborhood Hits	181
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

NRG2_MOUSE
θ value	0.0563607 (rank : 292)	NC score	0.236970 (rank : 344)
Query Neighborhood Hits	453	Target Neighborhood Hits	392	Shared Neighborhood Hits	123
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

ADA21_HUMAN
θ value	0.0736092 (rank : 293)	NC score	0.110741 (rank : 486)
Query Neighborhood Hits	453	Target Neighborhood Hits	181	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

EPHB6_HUMAN
θ value	0.0736092 (rank : 294)	NC score	0.024602 (rank : 779)
Query Neighborhood Hits	453	Target Neighborhood Hits	912	Shared Neighborhood Hits	81
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

GP179_HUMAN
θ value	0.0736092 (rank : 295)	NC score	0.069630 (rank : 621)
Query Neighborhood Hits	453	Target Neighborhood Hits	372	Shared Neighborhood Hits	45
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

MATN4_MOUSE
θ value	0.0736092 (rank : 296)	NC score	0.529937 (rank : 176)
Query Neighborhood Hits	453	Target Neighborhood Hits	277	Shared Neighborhood Hits	213
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MKS3_HUMAN
θ value	0.0736092 (rank : 297)	NC score	0.146290 (rank : 420)
Query Neighborhood Hits	453	Target Neighborhood Hits	79	Shared Neighborhood Hits	69
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

TDGF1_HUMAN
θ value	0.0736092 (rank : 298)	NC score	0.371077 (rank : 258)
Query Neighborhood Hits	453	Target Neighborhood Hits	132	Shared Neighborhood Hits	128
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

CO8B_MOUSE
θ value	0.0961366 (rank : 299)	NC score	0.191171 (rank : 373)
Query Neighborhood Hits	453	Target Neighborhood Hits	224	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

KR109_HUMAN
θ value	0.0961366 (rank : 300)	NC score	0.416846 (rank : 236)
Query Neighborhood Hits	453	Target Neighborhood Hits	226	Shared Neighborhood Hits	152
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

LYPD1_MOUSE
θ value	0.0961366 (rank : 301)	NC score	0.062245 (rank : 651)
Query Neighborhood Hits	453	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BLC3, Q3V2X5, Q3V447, Q9JJ96	Gene names	Lypd1, Lypdc1
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 1 precursor.

SHBG_MOUSE
θ value	0.0961366 (rank : 302)	NC score	0.165584 (rank : 399)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	42
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

ADAM9_HUMAN
θ value	0.125558 (rank : 303)	NC score	0.134407 (rank : 445)
Query Neighborhood Hits	453	Target Neighborhood Hits	243	Shared Neighborhood Hits	151
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

KRA58_HUMAN
θ value	0.125558 (rank : 304)	NC score	0.589584 (rank : 143)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	211
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LRP10_HUMAN
θ value	0.125558 (rank : 305)	NC score	0.135706 (rank : 441)
Query Neighborhood Hits	453	Target Neighborhood Hits	197	Shared Neighborhood Hits	90
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

PGH1_HUMAN
θ value	0.125558 (rank : 306)	NC score	0.201808 (rank : 368)
Query Neighborhood Hits	453	Target Neighborhood Hits	91	Shared Neighborhood Hits	77
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

ADA12_HUMAN
θ value	0.163984 (rank : 307)	NC score	0.121311 (rank : 467)
Query Neighborhood Hits	453	Target Neighborhood Hits	224	Shared Neighborhood Hits	135
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

KR171_HUMAN
θ value	0.163984 (rank : 308)	NC score	0.480488 (rank : 204)
Query Neighborhood Hits	453	Target Neighborhood Hits	144	Shared Neighborhood Hits	112
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

TNR12_HUMAN
θ value	0.163984 (rank : 309)	NC score	0.025468 (rank : 778)
Query Neighborhood Hits	453	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NP84, Q9HCS0	Gene names	TNFRSF12A, FN14
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 12A precursor (Fibroblast growth factor-inducible immediate-early response protein 14) (FGF-inducible 14) (Tweak-receptor) (TweakR) (CD266 antigen).

C1RA_MOUSE
θ value	0.21417 (rank : 310)	NC score	0.168491 (rank : 395)
Query Neighborhood Hits	453	Target Neighborhood Hits	379	Shared Neighborhood Hits	157
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	0.21417 (rank : 311)	NC score	0.165749 (rank : 398)
Query Neighborhood Hits	453	Target Neighborhood Hits	380	Shared Neighborhood Hits	156
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

EPHB6_MOUSE
θ value	0.21417 (rank : 312)	NC score	0.017474 (rank : 786)
Query Neighborhood Hits	453	Target Neighborhood Hits	906	Shared Neighborhood Hits	59
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

IGF1R_HUMAN
θ value	0.21417 (rank : 313)	NC score	0.015224 (rank : 787)
Query Neighborhood Hits	453	Target Neighborhood Hits	977	Shared Neighborhood Hits	96
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

KRA93_HUMAN
θ value	0.21417 (rank : 314)	NC score	0.347009 (rank : 274)
Query Neighborhood Hits	453	Target Neighborhood Hits	203	Shared Neighborhood Hits	127
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

TDGF2_HUMAN
θ value	0.21417 (rank : 315)	NC score	0.362460 (rank : 263)
Query Neighborhood Hits	453	Target Neighborhood Hits	131	Shared Neighborhood Hits	125
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

APR3_MOUSE
θ value	0.279714 (rank : 316)	NC score	0.208033 (rank : 359)
Query Neighborhood Hits	453	Target Neighborhood Hits	61	Shared Neighborhood Hits	57
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

FSTL3_MOUSE
θ value	0.279714 (rank : 317)	NC score	0.166429 (rank : 397)
Query Neighborhood Hits	453	Target Neighborhood Hits	152	Shared Neighborhood Hits	81
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

KR10B_HUMAN
θ value	0.279714 (rank : 318)	NC score	0.376585 (rank : 256)
Query Neighborhood Hits	453	Target Neighborhood Hits	269	Shared Neighborhood Hits	170
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

MEP1A_MOUSE
θ value	0.279714 (rank : 319)	NC score	0.238076 (rank : 342)
Query Neighborhood Hits	453	Target Neighborhood Hits	166	Shared Neighborhood Hits	134
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MUC2_HUMAN
θ value	0.279714 (rank : 320)	NC score	0.182594 (rank : 384)
Query Neighborhood Hits	453	Target Neighborhood Hits	906	Shared Neighborhood Hits	166
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PGH2_HUMAN
θ value	0.279714 (rank : 321)	NC score	0.240580 (rank : 339)
Query Neighborhood Hits	453	Target Neighborhood Hits	103	Shared Neighborhood Hits	93
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

SC6A5_MOUSE
θ value	0.279714 (rank : 322)	NC score	0.002053 (rank : 793)
Query Neighborhood Hits	453	Target Neighborhood Hits	135	Shared Neighborhood Hits	6
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

TLL2_HUMAN
θ value	0.279714 (rank : 323)	NC score	0.247438 (rank : 335)
Query Neighborhood Hits	453	Target Neighborhood Hits	241	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

UROK_HUMAN
θ value	0.279714 (rank : 324)	NC score	0.116327 (rank : 476)
Query Neighborhood Hits	453	Target Neighborhood Hits	272	Shared Neighborhood Hits	115
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

ADM1B_MOUSE
θ value	0.365318 (rank : 325)	NC score	0.104005 (rank : 500)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	120
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

HYAL3_MOUSE
θ value	0.365318 (rank : 326)	NC score	0.059329 (rank : 673)
Query Neighborhood Hits	453	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VEI3, Q8VBX7, Q8VI77	Gene names	Hyal3, Hyl3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3).

PGH1_MOUSE
θ value	0.365318 (rank : 327)	NC score	0.230851 (rank : 349)
Query Neighborhood Hits	453	Target Neighborhood Hits	100	Shared Neighborhood Hits	84
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

SORL_HUMAN
θ value	0.365318 (rank : 328)	NC score	0.351107 (rank : 270)
Query Neighborhood Hits	453	Target Neighborhood Hits	440	Shared Neighborhood Hits	215
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

ZNFX1_MOUSE
θ value	0.365318 (rank : 329)	NC score	0.087317 (rank : 550)
Query Neighborhood Hits	453	Target Neighborhood Hits	407	Shared Neighborhood Hits	101
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ADAM7_HUMAN
θ value	0.47712 (rank : 330)	NC score	0.131102 (rank : 450)
Query Neighborhood Hits	453	Target Neighborhood Hits	221	Shared Neighborhood Hits	150
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

APR3_HUMAN
θ value	0.47712 (rank : 331)	NC score	0.185941 (rank : 379)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	49
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

CFC1_HUMAN
θ value	0.47712 (rank : 332)	NC score	0.457381 (rank : 220)
Query Neighborhood Hits	453	Target Neighborhood Hits	148	Shared Neighborhood Hits	144
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CLC14_HUMAN
θ value	0.47712 (rank : 333)	NC score	0.263022 (rank : 325)
Query Neighborhood Hits	453	Target Neighborhood Hits	143	Shared Neighborhood Hits	112
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

EPGN_MOUSE
θ value	0.47712 (rank : 334)	NC score	0.145729 (rank : 421)
Query Neighborhood Hits	453	Target Neighborhood Hits	63	Shared Neighborhood Hits	52
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

MEP1A_HUMAN
θ value	0.47712 (rank : 335)	NC score	0.228874 (rank : 352)
Query Neighborhood Hits	453	Target Neighborhood Hits	162	Shared Neighborhood Hits	135
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

RELN_MOUSE
θ value	0.47712 (rank : 336)	NC score	0.252234 (rank : 330)
Query Neighborhood Hits	453	Target Neighborhood Hits	235	Shared Neighborhood Hits	179
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

ADA15_HUMAN
θ value	0.62314 (rank : 337)	NC score	0.146855 (rank : 419)
Query Neighborhood Hits	453	Target Neighborhood Hits	288	Shared Neighborhood Hits	178
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA33_MOUSE
θ value	0.62314 (rank : 338)	NC score	0.135752 (rank : 440)
Query Neighborhood Hits	453	Target Neighborhood Hits	231	Shared Neighborhood Hits	148
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

CFC1_MOUSE
θ value	0.62314 (rank : 339)	NC score	0.430419 (rank : 231)
Query Neighborhood Hits	453	Target Neighborhood Hits	125	Shared Neighborhood Hits	124
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

ITB3_MOUSE
θ value	0.62314 (rank : 340)	NC score	0.466893 (rank : 213)
Query Neighborhood Hits	453	Target Neighborhood Hits	319	Shared Neighborhood Hits	238
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

KRA53_HUMAN
θ value	0.62314 (rank : 341)	NC score	0.623222 (rank : 124)
Query Neighborhood Hits	453	Target Neighborhood Hits	331	Shared Neighborhood Hits	222
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA55_HUMAN
θ value	0.62314 (rank : 342)	NC score	0.520285 (rank : 180)
Query Neighborhood Hits	453	Target Neighborhood Hits	257	Shared Neighborhood Hits	183
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

LYPD1_HUMAN
θ value	0.62314 (rank : 343)	NC score	0.058007 (rank : 677)
Query Neighborhood Hits	453	Target Neighborhood Hits	24	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N2G4, Q96AC2	Gene names	LYPD1, LYPDC1
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 1 precursor.

MASP2_HUMAN
θ value	0.62314 (rank : 344)	NC score	0.141249 (rank : 430)
Query Neighborhood Hits	453	Target Neighborhood Hits	364	Shared Neighborhood Hits	144
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

NET4_HUMAN
θ value	0.62314 (rank : 345)	NC score	0.389338 (rank : 249)
Query Neighborhood Hits	453	Target Neighborhood Hits	191	Shared Neighborhood Hits	156
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NRG1_HUMAN
θ value	0.62314 (rank : 346)	NC score	0.231129 (rank : 347)
Query Neighborhood Hits	453	Target Neighborhood Hits	285	Shared Neighborhood Hits	96
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

PGH2_MOUSE
θ value	0.62314 (rank : 347)	NC score	0.263395 (rank : 324)
Query Neighborhood Hits	453	Target Neighborhood Hits	113	Shared Neighborhood Hits	104
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

TLL2_MOUSE
θ value	0.62314 (rank : 348)	NC score	0.238767 (rank : 341)
Query Neighborhood Hits	453	Target Neighborhood Hits	240	Shared Neighborhood Hits	166
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

UROL1_MOUSE
θ value	0.62314 (rank : 349)	NC score	0.290520 (rank : 311)
Query Neighborhood Hits	453	Target Neighborhood Hits	235	Shared Neighborhood Hits	140
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ADA23_MOUSE
θ value	0.813845 (rank : 350)	NC score	0.161813 (rank : 406)
Query Neighborhood Hits	453	Target Neighborhood Hits	245	Shared Neighborhood Hits	169
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

CO9_MOUSE
θ value	0.813845 (rank : 351)	NC score	0.159192 (rank : 408)
Query Neighborhood Hits	453	Target Neighborhood Hits	153	Shared Neighborhood Hits	91
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

IGF1R_MOUSE
θ value	0.813845 (rank : 352)	NC score	0.019969 (rank : 785)
Query Neighborhood Hits	453	Target Neighborhood Hits	973	Shared Neighborhood Hits	103
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

MKS3_MOUSE
θ value	0.813845 (rank : 353)	NC score	0.152692 (rank : 413)
Query Neighborhood Hits	453	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

NRG2_HUMAN
θ value	0.813845 (rank : 354)	NC score	0.196462 (rank : 370)
Query Neighborhood Hits	453	Target Neighborhood Hits	419	Shared Neighborhood Hits	108
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG3_HUMAN
θ value	0.813845 (rank : 355)	NC score	0.100326 (rank : 511)
Query Neighborhood Hits	453	Target Neighborhood Hits	119	Shared Neighborhood Hits	64
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRG3_MOUSE
θ value	0.813845 (rank : 356)	NC score	0.102360 (rank : 506)
Query Neighborhood Hits	453	Target Neighborhood Hits	132	Shared Neighborhood Hits	70
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

RELN_HUMAN
θ value	0.813845 (rank : 357)	NC score	0.240451 (rank : 340)
Query Neighborhood Hits	453	Target Neighborhood Hits	233	Shared Neighborhood Hits	176
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

ADA25_MOUSE
θ value	1.06291 (rank : 358)	NC score	0.111743 (rank : 485)
Query Neighborhood Hits	453	Target Neighborhood Hits	213	Shared Neighborhood Hits	133
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

CO9_HUMAN
θ value	1.06291 (rank : 359)	NC score	0.145511 (rank : 423)
Query Neighborhood Hits	453	Target Neighborhood Hits	147	Shared Neighborhood Hits	88
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

KRA45_HUMAN
θ value	1.06291 (rank : 360)	NC score	0.323643 (rank : 288)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	126
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

MT3_HUMAN
θ value	1.06291 (rank : 361)	NC score	0.179146 (rank : 387)
Query Neighborhood Hits	453	Target Neighborhood Hits	82	Shared Neighborhood Hits	54
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MUC13_HUMAN
θ value	1.06291 (rank : 362)	NC score	0.213837 (rank : 357)
Query Neighborhood Hits	453	Target Neighborhood Hits	164	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

NET4_MOUSE
θ value	1.06291 (rank : 363)	NC score	0.383266 (rank : 253)
Query Neighborhood Hits	453	Target Neighborhood Hits	180	Shared Neighborhood Hits	152
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

SHBG_HUMAN
θ value	1.06291 (rank : 364)	NC score	0.168652 (rank : 394)
Query Neighborhood Hits	453	Target Neighborhood Hits	45	Shared Neighborhood Hits	37
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

TLL1_HUMAN
θ value	1.06291 (rank : 365)	NC score	0.246081 (rank : 337)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	164
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	1.06291 (rank : 366)	NC score	0.253601 (rank : 329)
Query Neighborhood Hits	453	Target Neighborhood Hits	237	Shared Neighborhood Hits	167
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

ADA30_HUMAN
θ value	1.38821 (rank : 367)	NC score	0.124597 (rank : 458)
Query Neighborhood Hits	453	Target Neighborhood Hits	391	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

BMP1_HUMAN
θ value	1.38821 (rank : 368)	NC score	0.251697 (rank : 331)
Query Neighborhood Hits	453	Target Neighborhood Hits	233	Shared Neighborhood Hits	168
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	1.38821 (rank : 369)	NC score	0.253659 (rank : 328)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	169
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

C1S_HUMAN
θ value	1.38821 (rank : 370)	NC score	0.138349 (rank : 436)
Query Neighborhood Hits	453	Target Neighborhood Hits	359	Shared Neighborhood Hits	143
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CS1B_MOUSE
θ value	1.38821 (rank : 371)	NC score	0.142540 (rank : 428)
Query Neighborhood Hits	453	Target Neighborhood Hits	361	Shared Neighborhood Hits	137
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

LRP5_HUMAN
θ value	1.38821 (rank : 372)	NC score	0.232542 (rank : 346)
Query Neighborhood Hits	453	Target Neighborhood Hits	224	Shared Neighborhood Hits	148
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

MMRN2_HUMAN
θ value	1.38821 (rank : 373)	NC score	0.026509 (rank : 777)
Query Neighborhood Hits	453	Target Neighborhood Hits	400	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

NRG4_HUMAN
θ value	1.38821 (rank : 374)	NC score	0.231041 (rank : 348)
Query Neighborhood Hits	453	Target Neighborhood Hits	85	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

PERT_MOUSE
θ value	1.38821 (rank : 375)	NC score	0.287096 (rank : 315)
Query Neighborhood Hits	453	Target Neighborhood Hits	221	Shared Neighborhood Hits	157
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

VWF_HUMAN
θ value	1.38821 (rank : 376)	NC score	0.285832 (rank : 316)
Query Neighborhood Hits	453	Target Neighborhood Hits	396	Shared Neighborhood Hits	203
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ADA12_MOUSE
θ value	1.81305 (rank : 377)	NC score	0.100878 (rank : 509)
Query Neighborhood Hits	453	Target Neighborhood Hits	474	Shared Neighborhood Hits	113
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

CD320_HUMAN
θ value	1.81305 (rank : 378)	NC score	0.147443 (rank : 417)
Query Neighborhood Hits	453	Target Neighborhood Hits	103	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CEP68_MOUSE
θ value	1.81305 (rank : 379)	NC score	0.008335 (rank : 791)
Query Neighborhood Hits	453	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0D9, Q3US49, Q5SW85, Q8R2V0	Gene names	Cep68
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

CORIN_HUMAN
θ value	1.81305 (rank : 380)	NC score	0.203464 (rank : 363)
Query Neighborhood Hits	453	Target Neighborhood Hits	453	Shared Neighborhood Hits	203
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CS1A_MOUSE
θ value	1.81305 (rank : 381)	NC score	0.143727 (rank : 426)
Query Neighborhood Hits	453	Target Neighborhood Hits	360	Shared Neighborhood Hits	137
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

EMR3_HUMAN
θ value	1.81305 (rank : 382)	NC score	0.347126 (rank : 272)
Query Neighborhood Hits	453	Target Neighborhood Hits	245	Shared Neighborhood Hits	157
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EPHB4_HUMAN
θ value	1.81305 (rank : 383)	NC score	0.044607 (rank : 773)
Query Neighborhood Hits	453	Target Neighborhood Hits	1056	Shared Neighborhood Hits	132
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

HYAL3_HUMAN
θ value	1.81305 (rank : 384)	NC score	0.057138 (rank : 687)
Query Neighborhood Hits	453	Target Neighborhood Hits	45	Shared Neighborhood Hits	37
SwissProt Accessions	O43820, O60540, Q8NFK2, Q8NFK3, Q8NFK4, Q96E56, Q9BRW9	Gene names	HYAL3, LUCA3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3) (LUCA-3).

PCSK6_HUMAN
θ value	1.81305 (rank : 385)	NC score	0.180973 (rank : 385)
Query Neighborhood Hits	453	Target Neighborhood Hits	298	Shared Neighborhood Hits	142
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

SMDF_HUMAN
θ value	1.81305 (rank : 386)	NC score	0.242332 (rank : 338)
Query Neighborhood Hits	453	Target Neighborhood Hits	117	Shared Neighborhood Hits	82
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

ADA23_HUMAN
θ value	2.36792 (rank : 387)	NC score	0.166635 (rank : 396)
Query Neighborhood Hits	453	Target Neighborhood Hits	235	Shared Neighborhood Hits	153
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADAM2_HUMAN
θ value	2.36792 (rank : 388)	NC score	0.110441 (rank : 487)
Query Neighborhood Hits	453	Target Neighborhood Hits	175	Shared Neighborhood Hits	108
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

CO8A_HUMAN
θ value	2.36792 (rank : 389)	NC score	0.139913 (rank : 431)
Query Neighborhood Hits	453	Target Neighborhood Hits	200	Shared Neighborhood Hits	95
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

EPGN_HUMAN
θ value	2.36792 (rank : 390)	NC score	0.124194 (rank : 461)
Query Neighborhood Hits	453	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EREG_HUMAN
θ value	2.36792 (rank : 391)	NC score	0.179836 (rank : 386)
Query Neighborhood Hits	453	Target Neighborhood Hits	73	Shared Neighborhood Hits	59
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

KRA98_HUMAN
θ value	2.36792 (rank : 392)	NC score	0.341312 (rank : 279)
Query Neighborhood Hits	453	Target Neighborhood Hits	185	Shared Neighborhood Hits	120
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

MEP1B_HUMAN
θ value	2.36792 (rank : 393)	NC score	0.091314 (rank : 540)
Query Neighborhood Hits	453	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MT3_MOUSE
θ value	2.36792 (rank : 394)	NC score	0.184846 (rank : 380)
Query Neighborhood Hits	453	Target Neighborhood Hits	68	Shared Neighborhood Hits	46
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

NRG4_MOUSE
θ value	2.36792 (rank : 395)	NC score	0.219430 (rank : 354)
Query Neighborhood Hits	453	Target Neighborhood Hits	79	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

TITF1_HUMAN
θ value	2.36792 (rank : 396)	NC score	-0.006024 (rank : 799)
Query Neighborhood Hits	453	Target Neighborhood Hits	332	Shared Neighborhood Hits	2
SwissProt Accessions	P43699, O14954, O14955, Q9BRJ8	Gene names	TITF1, NKX2-1, NKX2A, TTF1
Domain Architecture
Description	Thyroid transcription factor 1 (Thyroid nuclear factor 1) (TTF-1) (Homeobox protein Nkx-2.1) (Homeobox protein NK-2 homolog A).

ZNFX1_HUMAN
θ value	2.36792 (rank : 397)	NC score	0.088646 (rank : 548)
Query Neighborhood Hits	453	Target Neighborhood Hits	308	Shared Neighborhood Hits	96
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

CO6_HUMAN
θ value	3.0926 (rank : 398)	NC score	0.208180 (rank : 358)
Query Neighborhood Hits	453	Target Neighborhood Hits	331	Shared Neighborhood Hits	157
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

LCE2B_HUMAN
θ value	3.0926 (rank : 399)	NC score	0.136867 (rank : 437)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LIMD1_MOUSE
θ value	3.0926 (rank : 400)	NC score	0.001067 (rank : 794)
Query Neighborhood Hits	453	Target Neighborhood Hits	291	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

MASP1_HUMAN
θ value	3.0926 (rank : 401)	NC score	0.133502 (rank : 447)
Query Neighborhood Hits	453	Target Neighborhood Hits	369	Shared Neighborhood Hits	144
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

UROL1_HUMAN
θ value	3.0926 (rank : 402)	NC score	0.267426 (rank : 323)
Query Neighborhood Hits	453	Target Neighborhood Hits	213	Shared Neighborhood Hits	133
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ADA18_MOUSE
θ value	4.03905 (rank : 403)	NC score	0.136372 (rank : 439)
Query Neighborhood Hits	453	Target Neighborhood Hits	227	Shared Neighborhood Hits	144
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

CO8B_HUMAN
θ value	4.03905 (rank : 404)	NC score	0.141627 (rank : 429)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	86
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

EREG_MOUSE
θ value	4.03905 (rank : 405)	NC score	0.113853 (rank : 481)
Query Neighborhood Hits	453	Target Neighborhood Hits	65	Shared Neighborhood Hits	48
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

F19A3_HUMAN
θ value	4.03905 (rank : 406)	NC score	0.015177 (rank : 788)
Query Neighborhood Hits	453	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z5A8, Q7Z5A6	Gene names	FAM19A3, TAFA3
Domain Architecture	No domain graphic available
Description	Protein FAM19A3 precursor (Chemokine-like protein TAFA-3).

MASP1_MOUSE
θ value	4.03905 (rank : 407)	NC score	0.131160 (rank : 449)
Query Neighborhood Hits	453	Target Neighborhood Hits	364	Shared Neighborhood Hits	145
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

ODFP_MOUSE
θ value	4.03905 (rank : 408)	NC score	0.075849 (rank : 594)
Query Neighborhood Hits	453	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

SPR2H_MOUSE
θ value	4.03905 (rank : 409)	NC score	0.086074 (rank : 554)
Query Neighborhood Hits	453	Target Neighborhood Hits	82	Shared Neighborhood Hits	22
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

AAA1_MOUSE
θ value	5.27518 (rank : 410)	NC score	0.000749 (rank : 795)
Query Neighborhood Hits	453	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P63115, Q9CW25, Q9JMH8	Gene names	Slc7a10, Asc1
Domain Architecture	No domain graphic available
Description	Asc-type amino acid transporter 1 (Asc-1) (D-serine transporter).

ADA24_MOUSE
θ value	5.27518 (rank : 411)	NC score	0.108660 (rank : 491)
Query Neighborhood Hits	453	Target Neighborhood Hits	230	Shared Neighborhood Hits	145
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADM1A_MOUSE
θ value	5.27518 (rank : 412)	NC score	0.118501 (rank : 473)
Query Neighborhood Hits	453	Target Neighborhood Hits	230	Shared Neighborhood Hits	151
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

BACH2_HUMAN
θ value	5.27518 (rank : 413)	NC score	0.004453 (rank : 792)
Query Neighborhood Hits	453	Target Neighborhood Hits	234	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYV9, Q59H70, Q5T793, Q9NTS5	Gene names	BACH2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

CO8A_MOUSE
θ value	5.27518 (rank : 414)	NC score	0.129050 (rank : 452)
Query Neighborhood Hits	453	Target Neighborhood Hits	182	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

EPHA1_HUMAN
θ value	5.27518 (rank : 415)	NC score	0.023453 (rank : 780)
Query Neighborhood Hits	453	Target Neighborhood Hits	997	Shared Neighborhood Hits	96
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

FOXO4_HUMAN
θ value	5.27518 (rank : 416)	NC score	-0.000559 (rank : 797)
Query Neighborhood Hits	453	Target Neighborhood Hits	197	Shared Neighborhood Hits	6
SwissProt Accessions	P98177, O43821, Q13720, Q3KPF1, Q8TDK9	Gene names	MLLT7, AFX, AFX1, FOXO4
Domain Architecture
Description	Fork head domain transcription factor AFX1 (Forkhead box protein O4).

GPR98_MOUSE
θ value	5.27518 (rank : 417)	NC score	0.069351 (rank : 622)
Query Neighborhood Hits	453	Target Neighborhood Hits	206	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

KR124_HUMAN
θ value	5.27518 (rank : 418)	NC score	0.100029 (rank : 514)
Query Neighborhood Hits	453	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

LRP10_MOUSE
θ value	5.27518 (rank : 419)	NC score	0.133014 (rank : 448)
Query Neighborhood Hits	453	Target Neighborhood Hits	169	Shared Neighborhood Hits	88
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

MASP2_MOUSE
θ value	5.27518 (rank : 420)	NC score	0.139461 (rank : 433)
Query Neighborhood Hits	453	Target Neighborhood Hits	382	Shared Neighborhood Hits	150
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

RSPO3_HUMAN
θ value	5.27518 (rank : 421)	NC score	0.096539 (rank : 527)
Query Neighborhood Hits	453	Target Neighborhood Hits	128	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

SPR2D_MOUSE
θ value	5.27518 (rank : 422)	NC score	0.099367 (rank : 517)
Query Neighborhood Hits	453	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2I_MOUSE
θ value	5.27518 (rank : 423)	NC score	0.062948 (rank : 646)
Query Neighborhood Hits	453	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

TNR5_MOUSE
θ value	5.27518 (rank : 424)	NC score	0.077251 (rank : 589)
Query Neighborhood Hits	453	Target Neighborhood Hits	131	Shared Neighborhood Hits	60
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

ADA28_MOUSE
θ value	6.88961 (rank : 425)	NC score	0.116819 (rank : 475)
Query Neighborhood Hits	453	Target Neighborhood Hits	241	Shared Neighborhood Hits	143
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

C1R_HUMAN
θ value	6.88961 (rank : 426)	NC score	0.147957 (rank : 416)
Query Neighborhood Hits	453	Target Neighborhood Hits	364	Shared Neighborhood Hits	146
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

CLC14_MOUSE
θ value	6.88961 (rank : 427)	NC score	0.269383 (rank : 322)
Query Neighborhood Hits	453	Target Neighborhood Hits	120	Shared Neighborhood Hits	108
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CT075_MOUSE
θ value	6.88961 (rank : 428)	NC score	0.051188 (rank : 749)
Query Neighborhood Hits	453	Target Neighborhood Hits	358	Shared Neighborhood Hits	23
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

ERBB3_MOUSE
θ value	6.88961 (rank : 429)	NC score	0.013255 (rank : 790)
Query Neighborhood Hits	453	Target Neighborhood Hits	898	Shared Neighborhood Hits	73
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

FRAS1_HUMAN
θ value	6.88961 (rank : 430)	NC score	0.378997 (rank : 254)
Query Neighborhood Hits	453	Target Neighborhood Hits	759	Shared Neighborhood Hits	266
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GFRA3_HUMAN
θ value	6.88961 (rank : 431)	NC score	0.014129 (rank : 789)
Query Neighborhood Hits	453	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	O60609, Q6UW20, Q8IUZ2	Gene names	GFRA3
Domain Architecture
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

GP144_HUMAN
θ value	6.88961 (rank : 432)	NC score	0.113398 (rank : 482)
Query Neighborhood Hits	453	Target Neighborhood Hits	108	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

KR103_HUMAN
θ value	6.88961 (rank : 433)	NC score	0.304851 (rank : 302)
Query Neighborhood Hits	453	Target Neighborhood Hits	212	Shared Neighborhood Hits	131
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KRA94_HUMAN
θ value	6.88961 (rank : 434)	NC score	0.345878 (rank : 275)
Query Neighborhood Hits	453	Target Neighborhood Hits	204	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

MEP1B_MOUSE
θ value	6.88961 (rank : 435)	NC score	0.145609 (rank : 422)
Query Neighborhood Hits	453	Target Neighborhood Hits	127	Shared Neighborhood Hits	89
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

NEU1_MOUSE
θ value	6.88961 (rank : 436)	NC score	0.075302 (rank : 596)
Query Neighborhood Hits	453	Target Neighborhood Hits	64	Shared Neighborhood Hits	51
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

NFX1_HUMAN
θ value	6.88961 (rank : 437)	NC score	0.299570 (rank : 306)
Query Neighborhood Hits	453	Target Neighborhood Hits	405	Shared Neighborhood Hits	152
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

PCSK5_HUMAN
θ value	6.88961 (rank : 438)	NC score	0.215462 (rank : 355)
Query Neighborhood Hits	453	Target Neighborhood Hits	291	Shared Neighborhood Hits	171
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

SPY4_MOUSE
θ value	6.88961 (rank : 439)	NC score	0.039316 (rank : 774)
Query Neighborhood Hits	453	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WTP2, Q9QXV7	Gene names	Spry4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

TNR16_HUMAN
θ value	6.88961 (rank : 440)	NC score	0.135521 (rank : 443)
Query Neighborhood Hits	453	Target Neighborhood Hits	183	Shared Neighborhood Hits	89
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

DPF1_HUMAN
θ value	8.99809 (rank : 441)	NC score	-0.001755 (rank : 798)
Query Neighborhood Hits	453	Target Neighborhood Hits	136	Shared Neighborhood Hits	2
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

F19A1_HUMAN
θ value	8.99809 (rank : 442)	NC score	0.020999 (rank : 784)
Query Neighborhood Hits	453	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z5A9, Q8TCL8	Gene names	FAM19A1, TAFA1
Domain Architecture	No domain graphic available
Description	Protein FAM19A1 precursor (Chemokine-like protein TAFA-1).

F19A1_MOUSE
θ value	8.99809 (rank : 443)	NC score	0.021021 (rank : 783)
Query Neighborhood Hits	453	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TPG8	Gene names	Fam19a1, Tafa1
Domain Architecture	No domain graphic available
Description	Protein FAM19A1 precursor (Chemokine-like protein TAFA-1).

F19A2_HUMAN
θ value	8.99809 (rank : 444)	NC score	0.022272 (rank : 782)
Query Neighborhood Hits	453	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N3H0, Q4G0R9, Q68DK0, Q6GTX6	Gene names	FAM19A2, TAFA2
Domain Architecture	No domain graphic available
Description	Protein FAM19A2 precursor (Chemokine-like protein TAFA-2).

F19A2_MOUSE
θ value	8.99809 (rank : 445)	NC score	0.022325 (rank : 781)
Query Neighborhood Hits	453	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TPG7, Q5M9Q3	Gene names	Fam19a2, Tafa2
Domain Architecture	No domain graphic available
Description	Protein FAM19A2 precursor (Chemokine-like protein TAFA-2).

HYAL2_HUMAN
θ value	8.99809 (rank : 446)	NC score	0.027142 (rank : 776)
Query Neighborhood Hits	453	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q12891, O15177, Q9BW29	Gene names	HYAL2, LUCA2
Domain Architecture
Description	Hyaluronidase-2 precursor (EC 3.2.1.35) (Hyal-2) (Hyaluronoglucosaminidase-2) (LUCA-2).

INSRR_HUMAN
θ value	8.99809 (rank : 447)	NC score	0.034050 (rank : 775)
Query Neighborhood Hits	453	Target Neighborhood Hits	950	Shared Neighborhood Hits	103
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

KR414_HUMAN
θ value	8.99809 (rank : 448)	NC score	0.315713 (rank : 295)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	129
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KRA52_HUMAN
θ value	8.99809 (rank : 449)	NC score	0.428484 (rank : 233)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	164
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

LCE2C_HUMAN
θ value	8.99809 (rank : 450)	NC score	0.153838 (rank : 411)
Query Neighborhood Hits	453	Target Neighborhood Hits	53	Shared Neighborhood Hits	30
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

MUC13_MOUSE
θ value	8.99809 (rank : 451)	NC score	0.301417 (rank : 305)
Query Neighborhood Hits	453	Target Neighborhood Hits	447	Shared Neighborhood Hits	164
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

TGFA_HUMAN
θ value	8.99809 (rank : 452)	NC score	0.104280 (rank : 499)
Query Neighborhood Hits	453	Target Neighborhood Hits	61	Shared Neighborhood Hits	51
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

TP53B_MOUSE
θ value	8.99809 (rank : 453)	NC score	-0.000230 (rank : 796)
Query Neighborhood Hits	453	Target Neighborhood Hits	644	Shared Neighborhood Hits	15
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

AD26A_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.076946 (rank : 590)
Query Neighborhood Hits	453	Target Neighborhood Hits	165	Shared Neighborhood Hits	102
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA10_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.122896 (rank : 465)
Query Neighborhood Hits	453	Target Neighborhood Hits	189	Shared Neighborhood Hits	112
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.115896 (rank : 477)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	110
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA17_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.124089 (rank : 462)
Query Neighborhood Hits	453	Target Neighborhood Hits	223	Shared Neighborhood Hits	126
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA17_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.100257 (rank : 513)
Query Neighborhood Hits	453	Target Neighborhood Hits	201	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA18_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.114042 (rank : 480)
Query Neighborhood Hits	453	Target Neighborhood Hits	184	Shared Neighborhood Hits	125
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA20_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.068909 (rank : 623)
Query Neighborhood Hits	453	Target Neighborhood Hits	143	Shared Neighborhood Hits	77
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA21_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.120025 (rank : 469)
Query Neighborhood Hits	453	Target Neighborhood Hits	172	Shared Neighborhood Hits	116
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA22_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.115632 (rank : 478)
Query Neighborhood Hits	453	Target Neighborhood Hits	211	Shared Neighborhood Hits	125
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA22_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.124428 (rank : 459)
Query Neighborhood Hits	453	Target Neighborhood Hits	225	Shared Neighborhood Hits	130
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA28_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.119501 (rank : 471)
Query Neighborhood Hits	453	Target Neighborhood Hits	244	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA29_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.091274 (rank : 541)
Query Neighborhood Hits	453	Target Neighborhood Hits	247	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA32_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.110346 (rank : 489)
Query Neighborhood Hits	453	Target Neighborhood Hits	216	Shared Neighborhood Hits	135
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA32_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.103577 (rank : 502)
Query Neighborhood Hits	453	Target Neighborhood Hits	219	Shared Neighborhood Hits	141
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADAM2_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.128666 (rank : 453)
Query Neighborhood Hits	453	Target Neighborhood Hits	209	Shared Neighborhood Hits	131
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADAM7_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.101195 (rank : 508)
Query Neighborhood Hits	453	Target Neighborhood Hits	200	Shared Neighborhood Hits	127
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM9_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.143483 (rank : 427)
Query Neighborhood Hits	453	Target Neighborhood Hits	325	Shared Neighborhood Hits	164
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

AMGO3_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.051199 (rank : 748)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	11
SwissProt Accessions	Q86WK7, Q96JH6	Gene names	AMIGO3, ALI3, KIAA1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

AN36B_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.052974 (rank : 723)
Query Neighborhood Hits	453	Target Neighborhood Hits	294	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANFY1_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.050226 (rank : 769)
Query Neighborhood Hits	453	Target Neighborhood Hits	480	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.050173 (rank : 770)
Query Neighborhood Hits	453	Target Neighborhood Hits	480	Shared Neighborhood Hits	9
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANKR6_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.054205 (rank : 713)
Query Neighborhood Hits	453	Target Neighborhood Hits	439	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR15_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.062641 (rank : 648)
Query Neighborhood Hits	453	Target Neighborhood Hits	478	Shared Neighborhood Hits	8
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR23_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.055450 (rank : 706)
Query Neighborhood Hits	453	Target Neighborhood Hits	291	Shared Neighborhood Hits	8
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ANR23_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.050374 (rank : 763)
Query Neighborhood Hits	453	Target Neighborhood Hits	296	Shared Neighborhood Hits	8
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANR25_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.054159 (rank : 715)
Query Neighborhood Hits	453	Target Neighborhood Hits	350	Shared Neighborhood Hits	11
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ANR29_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.050833 (rank : 756)
Query Neighborhood Hits	453	Target Neighborhood Hits	294	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ANR33_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.051097 (rank : 750)
Query Neighborhood Hits	453	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR38_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.063390 (rank : 643)
Query Neighborhood Hits	453	Target Neighborhood Hits	443	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR38_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.065711 (rank : 632)
Query Neighborhood Hits	453	Target Neighborhood Hits	512	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR40_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.057357 (rank : 684)
Query Neighborhood Hits	453	Target Neighborhood Hits	224	Shared Neighborhood Hits	8
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.052710 (rank : 727)
Query Neighborhood Hits	453	Target Neighborhood Hits	228	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR41_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.050330 (rank : 764)
Query Neighborhood Hits	453	Target Neighborhood Hits	332	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ANR47_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.056017 (rank : 699)
Query Neighborhood Hits	453	Target Neighborhood Hits	369	Shared Neighborhood Hits	8
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANR47_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.056214 (rank : 698)
Query Neighborhood Hits	453	Target Neighborhood Hits	350	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANR49_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.052958 (rank : 724)
Query Neighborhood Hits	453	Target Neighborhood Hits	282	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ANR49_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.050393 (rank : 762)
Query Neighborhood Hits	453	Target Neighborhood Hits	285	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANR50_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.051518 (rank : 744)
Query Neighborhood Hits	453	Target Neighborhood Hits	361	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ASB14_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.051694 (rank : 742)
Query Neighborhood Hits	453	Target Neighborhood Hits	293	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASB16_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.062012 (rank : 652)
Query Neighborhood Hits	453	Target Neighborhood Hits	306	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB8_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.056239 (rank : 697)
Query Neighborhood Hits	453	Target Neighborhood Hits	294	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB8_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.055645 (rank : 703)
Query Neighborhood Hits	453	Target Neighborhood Hits	293	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASTN_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.151531 (rank : 414)
Query Neighborhood Hits	453	Target Neighborhood Hits	105	Shared Neighborhood Hits	78
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.149762 (rank : 415)
Query Neighborhood Hits	453	Target Neighborhood Hits	98	Shared Neighborhood Hits	75
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ASZ1_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.050246 (rank : 767)
Query Neighborhood Hits	453	Target Neighborhood Hits	341	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ASZ1_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.052677 (rank : 728)
Query Neighborhood Hits	453	Target Neighborhood Hits	319	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

BAI1_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.113357 (rank : 483)
Query Neighborhood Hits	453	Target Neighborhood Hits	375	Shared Neighborhood Hits	54
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.107599 (rank : 494)
Query Neighborhood Hits	453	Target Neighborhood Hits	340	Shared Neighborhood Hits	50
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.102325 (rank : 507)
Query Neighborhood Hits	453	Target Neighborhood Hits	332	Shared Neighborhood Hits	47
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.104318 (rank : 498)
Query Neighborhood Hits	453	Target Neighborhood Hits	323	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI3_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.108154 (rank : 493)
Query Neighborhood Hits	453	Target Neighborhood Hits	246	Shared Neighborhood Hits	54
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.110429 (rank : 488)
Query Neighborhood Hits	453	Target Neighborhood Hits	250	Shared Neighborhood Hits	58
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BCL3_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.058546 (rank : 676)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	8
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

BCL3_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.055663 (rank : 702)
Query Neighborhood Hits	453	Target Neighborhood Hits	388	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

BMPER_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.157671 (rank : 409)
Query Neighborhood Hits	453	Target Neighborhood Hits	175	Shared Neighborhood Hits	104
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.172265 (rank : 391)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	118
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

BTC_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.100271 (rank : 512)
Query Neighborhood Hits	453	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

BTC_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.117517 (rank : 474)
Query Neighborhood Hits	453	Target Neighborhood Hits	67	Shared Neighborhood Hits	55
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

CAD16_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.051961 (rank : 740)
Query Neighborhood Hits	453	Target Neighborhood Hits	159	Shared Neighborhood Hits	9
SwissProt Accessions	O75309, Q6UW93	Gene names	CDH16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

CAD16_MOUSE
θ value	θ > 10 (rank : 513)	NC score	0.051589 (rank : 743)
Query Neighborhood Hits	453	Target Neighborhood Hits	170	Shared Neighborhood Hits	10
SwissProt Accessions	O88338, Q9JLZ5	Gene names	Cdh16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

CAD17_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.053715 (rank : 717)
Query Neighborhood Hits	453	Target Neighborhood Hits	154	Shared Neighborhood Hits	8
SwissProt Accessions	Q12864, Q15336	Gene names	CDH17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (Intestinal peptide-associated transporter HPT-1).

CAD17_MOUSE
θ value	θ > 10 (rank : 515)	NC score	0.055633 (rank : 704)
Query Neighborhood Hits	453	Target Neighborhood Hits	157	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R100	Gene names	Cdh17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (BILL- cadherin) (P130).

CAD23_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.067574 (rank : 627)
Query Neighborhood Hits	453	Target Neighborhood Hits	197	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CAD23_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.067391 (rank : 628)
Query Neighborhood Hits	453	Target Neighborhood Hits	208	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CALCR_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.052009 (rank : 738)
Query Neighborhood Hits	453	Target Neighborhood Hits	67	Shared Neighborhood Hits	16
SwissProt Accessions	P30988, O14585, Q13941, Q6DJU8, Q6T712	Gene names	CALCR
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

CALCR_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.050747 (rank : 757)
Query Neighborhood Hits	453	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	Q60755	Gene names	Calcr
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

CD2A1_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.050945 (rank : 755)
Query Neighborhood Hits	453	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

CD2A1_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.073108 (rank : 602)
Query Neighborhood Hits	453	Target Neighborhood Hits	206	Shared Neighborhood Hits	8
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CDN2B_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.073343 (rank : 600)
Query Neighborhood Hits	453	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CDN2B_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.065230 (rank : 634)
Query Neighborhood Hits	453	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

CDN2D_MOUSE
θ value	θ > 10 (rank : 524)	NC score	0.051389 (rank : 746)
Query Neighborhood Hits	453	Target Neighborhood Hits	267	Shared Neighborhood Hits	8
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CFAB_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.054165 (rank : 714)
Query Neighborhood Hits	453	Target Neighborhood Hits	251	Shared Neighborhood Hits	50
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.060678 (rank : 661)
Query Neighborhood Hits	453	Target Neighborhood Hits	262	Shared Neighborhood Hits	55
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAI_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.079494 (rank : 581)
Query Neighborhood Hits	453	Target Neighborhood Hits	289	Shared Neighborhood Hits	79
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFAI_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.082245 (rank : 573)
Query Neighborhood Hits	453	Target Neighborhood Hits	290	Shared Neighborhood Hits	81
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CHRD_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.071316 (rank : 613)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.065124 (rank : 635)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CLPB_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.050719 (rank : 758)
Query Neighborhood Hits	453	Target Neighborhood Hits	289	Shared Neighborhood Hits	10
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

COCA1_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.059731 (rank : 670)
Query Neighborhood Hits	453	Target Neighborhood Hits	458	Shared Neighborhood Hits	35
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 533)	NC score	0.061908 (rank : 653)
Query Neighborhood Hits	453	Target Neighborhood Hits	467	Shared Neighborhood Hits	36
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.054294 (rank : 712)
Query Neighborhood Hits	453	Target Neighborhood Hits	427	Shared Neighborhood Hits	30
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	θ > 10 (rank : 535)	NC score	0.056758 (rank : 689)
Query Neighborhood Hits	453	Target Neighborhood Hits	402	Shared Neighborhood Hits	29
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

COKA1_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.059504 (rank : 671)
Query Neighborhood Hits	453	Target Neighborhood Hits	403	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CORIN_MOUSE
θ value	θ > 10 (rank : 537)	NC score	0.183383 (rank : 381)
Query Neighborhood Hits	453	Target Neighborhood Hits	451	Shared Neighborhood Hits	195
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CRAC1_HUMAN
θ value	θ > 10 (rank : 538)	NC score	0.287694 (rank : 314)
Query Neighborhood Hits	453	Target Neighborhood Hits	111	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 539)	NC score	0.289070 (rank : 313)
Query Neighborhood Hits	453	Target Neighborhood Hits	112	Shared Neighborhood Hits	96
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRDL2_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.060509 (rank : 664)
Query Neighborhood Hits	453	Target Neighborhood Hits	99	Shared Neighborhood Hits	40
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

CRDL2_MOUSE
θ value	θ > 10 (rank : 541)	NC score	0.065271 (rank : 633)
Query Neighborhood Hits	453	Target Neighborhood Hits	81	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.426381 (rank : 234)
Query Neighborhood Hits	453	Target Neighborhood Hits	362	Shared Neighborhood Hits	193
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CSMD1_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.067601 (rank : 625)
Query Neighborhood Hits	453	Target Neighborhood Hits	176	Shared Neighborhood Hits	62
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	θ > 10 (rank : 544)	NC score	0.068143 (rank : 624)
Query Neighborhood Hits	453	Target Neighborhood Hits	193	Shared Neighborhood Hits	71
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.060296 (rank : 666)
Query Neighborhood Hits	453	Target Neighborhood Hits	188	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD3_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.066732 (rank : 630)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSPG4_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.078021 (rank : 588)
Query Neighborhood Hits	453	Target Neighborhood Hits	112	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CSPG4_MOUSE
θ value	θ > 10 (rank : 548)	NC score	0.081244 (rank : 578)
Query Neighborhood Hits	453	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

CT127_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.095000 (rank : 530)
Query Neighborhood Hits	453	Target Neighborhood Hits	67	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CTGF_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.072760 (rank : 605)
Query Neighborhood Hits	453	Target Neighborhood Hits	128	Shared Neighborhood Hits	50
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CTGF_MOUSE
θ value	θ > 10 (rank : 551)	NC score	0.066926 (rank : 629)
Query Neighborhood Hits	453	Target Neighborhood Hits	124	Shared Neighborhood Hits	49
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

CYR61_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.078385 (rank : 587)
Query Neighborhood Hits	453	Target Neighborhood Hits	159	Shared Neighborhood Hits	59
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	θ > 10 (rank : 553)	NC score	0.082736 (rank : 567)
Query Neighborhood Hits	453	Target Neighborhood Hits	156	Shared Neighborhood Hits	57
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

DCBD1_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.073234 (rank : 601)
Query Neighborhood Hits	453	Target Neighborhood Hits	110	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.071410 (rank : 612)
Query Neighborhood Hits	453	Target Neighborhood Hits	118	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	θ > 10 (rank : 556)	NC score	0.070264 (rank : 618)
Query Neighborhood Hits	453	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DKK3_HUMAN
θ value	θ > 10 (rank : 557)	NC score	0.085512 (rank : 556)
Query Neighborhood Hits	453	Target Neighborhood Hits	74	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

DKK3_MOUSE
θ value	θ > 10 (rank : 558)	NC score	0.098292 (rank : 521)
Query Neighborhood Hits	453	Target Neighborhood Hits	83	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

ECM2_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.060964 (rank : 659)
Query Neighborhood Hits	453	Target Neighborhood Hits	402	Shared Neighborhood Hits	34
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

EHMT2_HUMAN
θ value	θ > 10 (rank : 560)	NC score	0.051082 (rank : 751)
Query Neighborhood Hits	453	Target Neighborhood Hits	498	Shared Neighborhood Hits	20
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EMR4_MOUSE
θ value	θ > 10 (rank : 561)	NC score	0.256468 (rank : 327)
Query Neighborhood Hits	453	Target Neighborhood Hits	191	Shared Neighborhood Hits	116
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

ENTK_HUMAN
θ value	θ > 10 (rank : 562)	NC score	0.064375 (rank : 638)
Query Neighborhood Hits	453	Target Neighborhood Hits	310	Shared Neighborhood Hits	78
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ENTK_MOUSE
θ value	θ > 10 (rank : 563)	NC score	0.069712 (rank : 619)
Query Neighborhood Hits	453	Target Neighborhood Hits	338	Shared Neighborhood Hits	86
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ESM1_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.202975 (rank : 365)
Query Neighborhood Hits	453	Target Neighborhood Hits	110	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ESM1_MOUSE
θ value	θ > 10 (rank : 565)	NC score	0.146907 (rank : 418)
Query Neighborhood Hits	453	Target Neighborhood Hits	107	Shared Neighborhood Hits	66
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FA5_HUMAN
θ value	θ > 10 (rank : 566)	NC score	0.056490 (rank : 691)
Query Neighborhood Hits	453	Target Neighborhood Hits	172	Shared Neighborhood Hits	16
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

FINC_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.091019 (rank : 543)
Query Neighborhood Hits	453	Target Neighborhood Hits	302	Shared Neighborhood Hits	52
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	θ > 10 (rank : 568)	NC score	0.091544 (rank : 539)
Query Neighborhood Hits	453	Target Neighborhood Hits	309	Shared Neighborhood Hits	58
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FRAS1_MOUSE
θ value	θ > 10 (rank : 569)	NC score	0.358816 (rank : 265)
Query Neighborhood Hits	453	Target Neighborhood Hits	747	Shared Neighborhood Hits	259
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FST_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.121103 (rank : 468)
Query Neighborhood Hits	453	Target Neighborhood Hits	129	Shared Neighborhood Hits	56
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.133571 (rank : 446)
Query Neighborhood Hits	453	Target Neighborhood Hits	146	Shared Neighborhood Hits	72
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

GABP2_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.053003 (rank : 721)
Query Neighborhood Hits	453	Target Neighborhood Hits	454	Shared Neighborhood Hits	8
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

GABP2_MOUSE
θ value	θ > 10 (rank : 573)	NC score	0.052595 (rank : 731)
Query Neighborhood Hits	453	Target Neighborhood Hits	429	Shared Neighborhood Hits	8
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

GABP3_MOUSE
θ value	θ > 10 (rank : 574)	NC score	0.054471 (rank : 711)
Query Neighborhood Hits	453	Target Neighborhood Hits	330	Shared Neighborhood Hits	9
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

GNPTA_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.090480 (rank : 544)
Query Neighborhood Hits	453	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GNPTA_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.089431 (rank : 547)
Query Neighborhood Hits	453	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GP110_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.084700 (rank : 560)
Query Neighborhood Hits	453	Target Neighborhood Hits	87	Shared Neighborhood Hits	23
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

GP110_MOUSE
θ value	θ > 10 (rank : 578)	NC score	0.084166 (rank : 562)
Query Neighborhood Hits	453	Target Neighborhood Hits	92	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

GP111_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.073990 (rank : 598)
Query Neighborhood Hits	453	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

GP112_HUMAN
θ value	θ > 10 (rank : 580)	NC score	0.096949 (rank : 525)
Query Neighborhood Hits	453	Target Neighborhood Hits	441	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GP113_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.106400 (rank : 497)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

GP114_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.096900 (rank : 526)
Query Neighborhood Hits	453	Target Neighborhood Hits	75	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

GP115_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.082629 (rank : 569)
Query Neighborhood Hits	453	Target Neighborhood Hits	87	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

GP115_MOUSE
θ value	θ > 10 (rank : 584)	NC score	0.085509 (rank : 557)
Query Neighborhood Hits	453	Target Neighborhood Hits	69	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

GP116_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.096031 (rank : 528)
Query Neighborhood Hits	453	Target Neighborhood Hits	167	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP123_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.082469 (rank : 571)
Query Neighborhood Hits	453	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

GP124_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.095739 (rank : 529)
Query Neighborhood Hits	453	Target Neighborhood Hits	304	Shared Neighborhood Hits	26
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP124_MOUSE
θ value	θ > 10 (rank : 588)	NC score	0.097420 (rank : 524)
Query Neighborhood Hits	453	Target Neighborhood Hits	423	Shared Neighborhood Hits	31
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP125_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.100028 (rank : 515)
Query Neighborhood Hits	453	Target Neighborhood Hits	327	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP125_MOUSE
θ value	θ > 10 (rank : 590)	NC score	0.094242 (rank : 534)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	27
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP126_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.103132 (rank : 503)
Query Neighborhood Hits	453	Target Neighborhood Hits	187	Shared Neighborhood Hits	39
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GP128_HUMAN
θ value	θ > 10 (rank : 592)	NC score	0.124287 (rank : 460)
Query Neighborhood Hits	453	Target Neighborhood Hits	135	Shared Neighborhood Hits	49
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP128_MOUSE
θ value	θ > 10 (rank : 593)	NC score	0.127574 (rank : 456)
Query Neighborhood Hits	453	Target Neighborhood Hits	141	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP133_HUMAN
θ value	θ > 10 (rank : 594)	NC score	0.108580 (rank : 492)
Query Neighborhood Hits	453	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP1BB_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.055356 (rank : 707)
Query Neighborhood Hits	453	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	P13224, Q8NG40	Gene names	GP1BB
Domain Architecture
Description	Platelet glycoprotein Ib beta chain precursor (GP-Ib beta) (GPIbB) (GPIb-beta) (Antigen CD42b-beta) (CD42c antigen).

GP1BB_MOUSE
θ value	θ > 10 (rank : 596)	NC score	0.053506 (rank : 718)
Query Neighborhood Hits	453	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	P56400	Gene names	Gp1bb
Domain Architecture
Description	Platelet glycoprotein Ib beta chain precursor (GP-Ib beta) (GPIbB) (GPIb-beta) (CD42c antigen).

GPIX_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.060478 (rank : 665)
Query Neighborhood Hits	453	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	P14770, Q14445, Q92525	Gene names	GP9
Domain Architecture
Description	Platelet glycoprotein IX precursor (GPIX) (CD42a antigen).

GPR56_HUMAN
θ value	θ > 10 (rank : 598)	NC score	0.092237 (rank : 537)
Query Neighborhood Hits	453	Target Neighborhood Hits	84	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

GPR56_MOUSE
θ value	θ > 10 (rank : 599)	NC score	0.091058 (rank : 542)
Query Neighborhood Hits	453	Target Neighborhood Hits	89	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

GPR64_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.097545 (rank : 523)
Query Neighborhood Hits	453	Target Neighborhood Hits	207	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GPR64_MOUSE
θ value	θ > 10 (rank : 601)	NC score	0.098095 (rank : 522)
Query Neighborhood Hits	453	Target Neighborhood Hits	156	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GPR97_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.080340 (rank : 579)
Query Neighborhood Hits	453	Target Neighborhood Hits	86	Shared Neighborhood Hits	16
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

GPR97_MOUSE
θ value	θ > 10 (rank : 603)	NC score	0.089976 (rank : 546)
Query Neighborhood Hits	453	Target Neighborhood Hits	89	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

GPR98_HUMAN
θ value	θ > 10 (rank : 604)	NC score	0.074338 (rank : 597)
Query Neighborhood Hits	453	Target Neighborhood Hits	202	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

HBEGF_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.100623 (rank : 510)
Query Neighborhood Hits	453	Target Neighborhood Hits	61	Shared Neighborhood Hits	49
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

HBEGF_MOUSE
θ value	θ > 10 (rank : 606)	NC score	0.070767 (rank : 616)
Query Neighborhood Hits	453	Target Neighborhood Hits	48	Shared Neighborhood Hits	39
SwissProt Accessions	Q06186	Gene names	Hbegf, Dtr, Hegfl
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF).

HECD1_HUMAN
θ value	θ > 10 (rank : 607)	NC score	0.054121 (rank : 716)
Query Neighborhood Hits	453	Target Neighborhood Hits	371	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

HPLN1_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.082191 (rank : 575)
Query Neighborhood Hits	453	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN1_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.082193 (rank : 574)
Query Neighborhood Hits	453	Target Neighborhood Hits	64	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN2_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.085738 (rank : 555)
Query Neighborhood Hits	453	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HPLN2_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.086981 (rank : 551)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

HPLN3_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.083620 (rank : 563)
Query Neighborhood Hits	453	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

HPLN3_MOUSE
θ value	θ > 10 (rank : 613)	NC score	0.085472 (rank : 558)
Query Neighborhood Hits	453	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

HPLN4_HUMAN
θ value	θ > 10 (rank : 614)	NC score	0.082185 (rank : 576)
Query Neighborhood Hits	453	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	Q86UW8, Q96PW2	Gene names	HAPLN4, BRAL2, KIAA1926
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2).

HPLN4_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.082787 (rank : 566)
Query Neighborhood Hits	453	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

IDD_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.072293 (rank : 607)
Query Neighborhood Hits	453	Target Neighborhood Hits	127	Shared Neighborhood Hits	40
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

IDD_MOUSE
θ value	θ > 10 (rank : 617)	NC score	0.069700 (rank : 620)
Query Neighborhood Hits	453	Target Neighborhood Hits	151	Shared Neighborhood Hits	39
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

IKBA_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.057400 (rank : 683)
Query Neighborhood Hits	453	Target Neighborhood Hits	280	Shared Neighborhood Hits	8
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

IKBA_MOUSE
θ value	θ > 10 (rank : 619)	NC score	0.054965 (rank : 709)
Query Neighborhood Hits	453	Target Neighborhood Hits	283	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

IKBE_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.059001 (rank : 674)
Query Neighborhood Hits	453	Target Neighborhood Hits	288	Shared Neighborhood Hits	8
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

IKBE_MOUSE
θ value	θ > 10 (rank : 621)	NC score	0.052359 (rank : 733)
Query Neighborhood Hits	453	Target Neighborhood Hits	308	Shared Neighborhood Hits	10
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

KR111_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.055492 (rank : 705)
Query Neighborhood Hits	453	Target Neighborhood Hits	90	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

KR122_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.094474 (rank : 533)
Query Neighborhood Hits	453	Target Neighborhood Hits	97	Shared Neighborhood Hits	51
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

KR241_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.071421 (rank : 611)
Query Neighborhood Hits	453	Target Neighborhood Hits	71	Shared Neighborhood Hits	43
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

KR410_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.206072 (rank : 361)
Query Neighborhood Hits	453	Target Neighborhood Hits	156	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 626)	NC score	0.276596 (rank : 320)
Query Neighborhood Hits	453	Target Neighborhood Hits	178	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR413_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.164888 (rank : 401)
Query Neighborhood Hits	453	Target Neighborhood Hits	112	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KR510_HUMAN
θ value	θ > 10 (rank : 628)	NC score	0.389489 (rank : 248)
Query Neighborhood Hits	453	Target Neighborhood Hits	217	Shared Neighborhood Hits	147
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.450644 (rank : 222)
Query Neighborhood Hits	453	Target Neighborhood Hits	231	Shared Neighborhood Hits	157
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA11_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.313109 (rank : 300)
Query Neighborhood Hits	453	Target Neighborhood Hits	155	Shared Neighborhood Hits	114
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.334303 (rank : 282)
Query Neighborhood Hits	453	Target Neighborhood Hits	144	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.280166 (rank : 319)
Query Neighborhood Hits	453	Target Neighborhood Hits	126	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA24_HUMAN
θ value	θ > 10 (rank : 633)	NC score	0.136866 (rank : 438)
Query Neighborhood Hits	453	Target Neighborhood Hits	192	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

KRA42_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.186931 (rank : 378)
Query Neighborhood Hits	453	Target Neighborhood Hits	149	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA44_HUMAN
θ value	θ > 10 (rank : 635)	NC score	0.325771 (rank : 285)
Query Neighborhood Hits	453	Target Neighborhood Hits	162	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA47_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.306955 (rank : 301)
Query Neighborhood Hits	453	Target Neighborhood Hits	204	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA54_HUMAN
θ value	θ > 10 (rank : 637)	NC score	0.496045 (rank : 195)
Query Neighborhood Hits	453	Target Neighborhood Hits	270	Shared Neighborhood Hits	178
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA56_HUMAN
θ value	θ > 10 (rank : 638)	NC score	0.423283 (rank : 235)
Query Neighborhood Hits	453	Target Neighborhood Hits	207	Shared Neighborhood Hits	157
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.520800 (rank : 179)
Query Neighborhood Hits	453	Target Neighborhood Hits	269	Shared Neighborhood Hits	188
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA59_HUMAN
θ value	θ > 10 (rank : 640)	NC score	0.525271 (rank : 177)
Query Neighborhood Hits	453	Target Neighborhood Hits	310	Shared Neighborhood Hits	190
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA92_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.314670 (rank : 297)
Query Neighborhood Hits	453	Target Neighborhood Hits	198	Shared Neighborhood Hits	126
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA99_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.294261 (rank : 309)
Query Neighborhood Hits	453	Target Neighborhood Hits	173	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

KREM1_HUMAN
θ value	θ > 10 (rank : 643)	NC score	0.060565 (rank : 663)
Query Neighborhood Hits	453	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_MOUSE
θ value	θ > 10 (rank : 644)	NC score	0.063610 (rank : 642)
Query Neighborhood Hits	453	Target Neighborhood Hits	92	Shared Neighborhood Hits	33
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.061562 (rank : 655)
Query Neighborhood Hits	453	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM2_MOUSE
θ value	θ > 10 (rank : 646)	NC score	0.059436 (rank : 672)
Query Neighborhood Hits	453	Target Neighborhood Hits	90	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

LCE1A_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.221699 (rank : 353)
Query Neighborhood Hits	453	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.304304 (rank : 304)
Query Neighborhood Hits	453	Target Neighborhood Hits	58	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.293605 (rank : 310)
Query Neighborhood Hits	453	Target Neighborhood Hits	65	Shared Neighborhood Hits	41
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 650)	NC score	0.269724 (rank : 321)
Query Neighborhood Hits	453	Target Neighborhood Hits	44	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.249047 (rank : 334)
Query Neighborhood Hits	453	Target Neighborhood Hits	53	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.229936 (rank : 351)
Query Neighborhood Hits	453	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 653)	NC score	0.139236 (rank : 434)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2D_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.135598 (rank : 442)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 655)	NC score	0.193867 (rank : 372)
Query Neighborhood Hits	453	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3B_HUMAN
θ value	θ > 10 (rank : 656)	NC score	0.118614 (rank : 472)
Query Neighborhood Hits	453	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LCE3C_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.067598 (rank : 626)
Query Neighborhood Hits	453	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

LCE4A_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.144954 (rank : 424)
Query Neighborhood Hits	453	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.090100 (rank : 545)
Query Neighborhood Hits	453	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LORI_MOUSE
θ value	θ > 10 (rank : 660)	NC score	0.139788 (rank : 432)
Query Neighborhood Hits	453	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LPHN1_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.102580 (rank : 505)
Query Neighborhood Hits	453	Target Neighborhood Hits	155	Shared Neighborhood Hits	16
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

LPHN2_HUMAN
θ value	θ > 10 (rank : 662)	NC score	0.103790 (rank : 501)
Query Neighborhood Hits	453	Target Neighborhood Hits	136	Shared Neighborhood Hits	18
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

LPHN3_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.102583 (rank : 504)
Query Neighborhood Hits	453	Target Neighborhood Hits	139	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

LRC17_HUMAN
θ value	θ > 10 (rank : 664)	NC score	0.057244 (rank : 685)
Query Neighborhood Hits	453	Target Neighborhood Hits	267	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N6Y2, Q13288, Q6UWA7, Q75MG5	Gene names	LRRC17, P37NB
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 17 precursor (p37NB).

LRC17_MOUSE
θ value	θ > 10 (rank : 665)	NC score	0.057992 (rank : 678)
Query Neighborhood Hits	453	Target Neighborhood Hits	268	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CXD9	Gene names	Lrrc17
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 17 precursor.

LRC21_HUMAN
θ value	θ > 10 (rank : 666)	NC score	0.062422 (rank : 650)
Query Neighborhood Hits	453	Target Neighborhood Hits	456	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRC21_MOUSE
θ value	θ > 10 (rank : 667)	NC score	0.060951 (rank : 660)
Query Neighborhood Hits	453	Target Neighborhood Hits	462	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRC24_HUMAN
θ value	θ > 10 (rank : 668)	NC score	0.056301 (rank : 694)
Query Neighborhood Hits	453	Target Neighborhood Hits	404	Shared Neighborhood Hits	16
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRC24_MOUSE
θ value	θ > 10 (rank : 669)	NC score	0.055061 (rank : 708)
Query Neighborhood Hits	453	Target Neighborhood Hits	387	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRC3B_HUMAN
θ value	θ > 10 (rank : 670)	NC score	0.050291 (rank : 765)
Query Neighborhood Hits	453	Target Neighborhood Hits	215	Shared Neighborhood Hits	9
SwissProt Accessions	Q96PB8	Gene names	LRRC3B, LRP15
Domain Architecture
Description	Leucine-rich repeat-containing protein 3B precursor (Leucine-rich repeat protein LRP15).

LRC3B_MOUSE
θ value	θ > 10 (rank : 671)	NC score	0.050283 (rank : 766)
Query Neighborhood Hits	453	Target Neighborhood Hits	215	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VCH9	Gene names	Lrrc3b, Lrp15
Domain Architecture
Description	Leucine-rich repeat-containing protein 3B precursor (Leucine-rich repeat protein LRP15).

LRC52_HUMAN
θ value	θ > 10 (rank : 672)	NC score	0.052611 (rank : 730)
Query Neighborhood Hits	453	Target Neighborhood Hits	229	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N7C0, Q5T9K5	Gene names	LRRC52
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 52 precursor.

LRC55_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.051397 (rank : 745)
Query Neighborhood Hits	453	Target Neighborhood Hits	257	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZSA7	Gene names	LRRC55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

LRC55_MOUSE
θ value	θ > 10 (rank : 674)	NC score	0.052339 (rank : 734)
Query Neighborhood Hits	453	Target Neighborhood Hits	254	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UY51	Gene names	Lrrc55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

LRP12_HUMAN
θ value	θ > 10 (rank : 675)	NC score	0.129670 (rank : 451)
Query Neighborhood Hits	453	Target Neighborhood Hits	205	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 676)	NC score	0.128526 (rank : 454)
Query Neighborhood Hits	453	Target Neighborhood Hits	180	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP3_HUMAN
θ value	θ > 10 (rank : 677)	NC score	0.165065 (rank : 400)
Query Neighborhood Hits	453	Target Neighborhood Hits	280	Shared Neighborhood Hits	122
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP5_MOUSE
θ value	θ > 10 (rank : 678)	NC score	0.238067 (rank : 343)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	151
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_HUMAN
θ value	θ > 10 (rank : 679)	NC score	0.250615 (rank : 333)
Query Neighborhood Hits	453	Target Neighborhood Hits	235	Shared Neighborhood Hits	158
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 680)	NC score	0.246439 (rank : 336)
Query Neighborhood Hits	453	Target Neighborhood Hits	232	Shared Neighborhood Hits	155
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MATN1_HUMAN
θ value	θ > 10 (rank : 681)	NC score	0.203407 (rank : 364)
Query Neighborhood Hits	453	Target Neighborhood Hits	191	Shared Neighborhood Hits	136
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 682)	NC score	0.202601 (rank : 366)
Query Neighborhood Hits	453	Target Neighborhood Hits	186	Shared Neighborhood Hits	131
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MCSP_MOUSE
θ value	θ > 10 (rank : 683)	NC score	0.135123 (rank : 444)
Query Neighborhood Hits	453	Target Neighborhood Hits	108	Shared Neighborhood Hits	52
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MFRP_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.072719 (rank : 606)
Query Neighborhood Hits	453	Target Neighborhood Hits	165	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 685)	NC score	0.061834 (rank : 654)
Query Neighborhood Hits	453	Target Neighborhood Hits	166	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MT1A_HUMAN
θ value	θ > 10 (rank : 686)	NC score	0.086946 (rank : 552)
Query Neighborhood Hits	453	Target Neighborhood Hits	74	Shared Neighborhood Hits	42
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1B_HUMAN
θ value	θ > 10 (rank : 687)	NC score	0.086391 (rank : 553)
Query Neighborhood Hits	453	Target Neighborhood Hits	87	Shared Neighborhood Hits	51
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MT1E_HUMAN
θ value	θ > 10 (rank : 688)	NC score	0.057435 (rank : 682)
Query Neighborhood Hits	453	Target Neighborhood Hits	75	Shared Neighborhood Hits	44
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MT1H_HUMAN
θ value	θ > 10 (rank : 689)	NC score	0.072216 (rank : 608)
Query Neighborhood Hits	453	Target Neighborhood Hits	78	Shared Neighborhood Hits	44
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

MT1L_HUMAN
θ value	θ > 10 (rank : 690)	NC score	0.051212 (rank : 747)
Query Neighborhood Hits	453	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

MT1X_HUMAN
θ value	θ > 10 (rank : 691)	NC score	0.082467 (rank : 572)
Query Neighborhood Hits	453	Target Neighborhood Hits	76	Shared Neighborhood Hits	45
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

MT1_MOUSE
θ value	θ > 10 (rank : 692)	NC score	0.063995 (rank : 640)
Query Neighborhood Hits	453	Target Neighborhood Hits	72	Shared Neighborhood Hits	37
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT2_MOUSE
θ value	θ > 10 (rank : 693)	NC score	0.071085 (rank : 614)
Query Neighborhood Hits	453	Target Neighborhood Hits	81	Shared Neighborhood Hits	40
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

MT4_HUMAN
θ value	θ > 10 (rank : 694)	NC score	0.119851 (rank : 470)
Query Neighborhood Hits	453	Target Neighborhood Hits	83	Shared Neighborhood Hits	52
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MT4_MOUSE
θ value	θ > 10 (rank : 695)	NC score	0.164870 (rank : 402)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	70
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

NETO1_HUMAN
θ value	θ > 10 (rank : 696)	NC score	0.061119 (rank : 657)
Query Neighborhood Hits	453	Target Neighborhood Hits	110	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 697)	NC score	0.060648 (rank : 662)
Query Neighborhood Hits	453	Target Neighborhood Hits	109	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 698)	NC score	0.057015 (rank : 688)
Query Neighborhood Hits	453	Target Neighborhood Hits	109	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 699)	NC score	0.057155 (rank : 686)
Query Neighborhood Hits	453	Target Neighborhood Hits	113	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NOV_HUMAN
θ value	θ > 10 (rank : 700)	NC score	0.051034 (rank : 752)
Query Neighborhood Hits	453	Target Neighborhood Hits	128	Shared Neighborhood Hits	48
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NRP1_HUMAN
θ value	θ > 10 (rank : 701)	NC score	0.072983 (rank : 603)
Query Neighborhood Hits	453	Target Neighborhood Hits	119	Shared Neighborhood Hits	40
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 702)	NC score	0.073537 (rank : 599)
Query Neighborhood Hits	453	Target Neighborhood Hits	120	Shared Neighborhood Hits	39
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 703)	NC score	0.078619 (rank : 586)
Query Neighborhood Hits	453	Target Neighborhood Hits	120	Shared Neighborhood Hits	40
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 704)	NC score	0.076206 (rank : 592)
Query Neighborhood Hits	453	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRX1B_HUMAN
θ value	θ > 10 (rank : 705)	NC score	0.099176 (rank : 518)
Query Neighborhood Hits	453	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	P58400	Gene names	NRXN1
Domain Architecture	No domain graphic available
Description	Neurexin-1-beta precursor (Neurexin I-beta).

NRX2B_HUMAN
θ value	θ > 10 (rank : 706)	NC score	0.052231 (rank : 735)
Query Neighborhood Hits	453	Target Neighborhood Hits	481	Shared Neighborhood Hits	28
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

NRX3B_HUMAN
θ value	θ > 10 (rank : 707)	NC score	0.091611 (rank : 538)
Query Neighborhood Hits	453	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HDB5	Gene names	NRXN3, KIAA0743
Domain Architecture	No domain graphic available
Description	Neurexin-3-beta precursor (Neurexin III-beta).

PA2G6_HUMAN
θ value	θ > 10 (rank : 708)	NC score	0.056446 (rank : 692)
Query Neighborhood Hits	453	Target Neighborhood Hits	284	Shared Neighborhood Hits	8
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PA2G6_MOUSE
θ value	θ > 10 (rank : 709)	NC score	0.056250 (rank : 696)
Query Neighborhood Hits	453	Target Neighborhood Hits	293	Shared Neighborhood Hits	8
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PAP2_HUMAN
θ value	θ > 10 (rank : 710)	NC score	0.055843 (rank : 700)
Query Neighborhood Hits	453	Target Neighborhood Hits	106	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PAPPA_HUMAN
θ value	θ > 10 (rank : 711)	NC score	0.085368 (rank : 559)
Query Neighborhood Hits	453	Target Neighborhood Hits	161	Shared Neighborhood Hits	74
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
θ value	θ > 10 (rank : 712)	NC score	0.088381 (rank : 549)
Query Neighborhood Hits	453	Target Neighborhood Hits	153	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PC11X_HUMAN
θ value	θ > 10 (rank : 713)	NC score	0.051009 (rank : 753)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BZA7, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5	Gene names	PCDH11X, PCDH11, PCDHX
Domain Architecture	No domain graphic available
Description	Protocadherin-11 X-linked precursor (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S).

PC11Y_HUMAN
θ value	θ > 10 (rank : 714)	NC score	0.050961 (rank : 754)
Query Neighborhood Hits	453	Target Neighborhood Hits	205	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BZA8, Q70LR6, Q70LR8, Q70LS0, Q70LS1, Q70LS2, Q70LS3, Q70LS4, Q70LS5, Q8WY34, Q9BZA9, Q9H4E1	Gene names	PCDH11Y, PCDH11, PCDH22, PCDHY
Domain Architecture	No domain graphic available
Description	Protocadherin-11 Y-linked precursor (Protocadherin-11) (Protocadherin- 22) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC).

PCD15_HUMAN
θ value	θ > 10 (rank : 715)	NC score	0.065977 (rank : 631)
Query Neighborhood Hits	453	Target Neighborhood Hits	289	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD15_MOUSE
θ value	θ > 10 (rank : 716)	NC score	0.064729 (rank : 637)
Query Neighborhood Hits	453	Target Neighborhood Hits	262	Shared Neighborhood Hits	15
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD16_HUMAN
θ value	θ > 10 (rank : 717)	NC score	0.064880 (rank : 636)
Query Neighborhood Hits	453	Target Neighborhood Hits	245	Shared Neighborhood Hits	16
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PCD20_HUMAN
θ value	θ > 10 (rank : 718)	NC score	0.051921 (rank : 741)
Query Neighborhood Hits	453	Target Neighborhood Hits	153	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N6Y1, Q8NDN4, Q9NRT9	Gene names	PCDH20
Domain Architecture	No domain graphic available
Description	Protocadherin-20 precursor (Protocadherin-13).

PCD20_MOUSE
θ value	θ > 10 (rank : 719)	NC score	0.051987 (rank : 739)
Query Neighborhood Hits	453	Target Neighborhood Hits	150	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BIZ0, Q8BIV2	Gene names	Pcdh20
Domain Architecture	No domain graphic available
Description	Protocadherin-20 precursor.

PCDH1_HUMAN
θ value	θ > 10 (rank : 720)	NC score	0.053504 (rank : 719)
Query Neighborhood Hits	453	Target Neighborhood Hits	174	Shared Neighborhood Hits	10
SwissProt Accessions	Q08174	Gene names	PCDH1
Domain Architecture
Description	Protocadherin-1 precursor (Protocadherin-42) (PC42) (Cadherin-like protein 1).

PCDH7_HUMAN
θ value	θ > 10 (rank : 721)	NC score	0.052661 (rank : 729)
Query Neighborhood Hits	453	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

PCDH9_HUMAN
θ value	θ > 10 (rank : 722)	NC score	0.052031 (rank : 737)
Query Neighborhood Hits	453	Target Neighborhood Hits	180	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HC56	Gene names	PCDH9
Domain Architecture
Description	Protocadherin-9 precursor.

PCDLK_HUMAN
θ value	θ > 10 (rank : 723)	NC score	0.061399 (rank : 656)
Query Neighborhood Hits	453	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYE9, Q9NXP8	Gene names	PCLKC
Domain Architecture	No domain graphic available
Description	Protocadherin LKC precursor (PC-LKC).

PGCA_MOUSE
θ value	θ > 10 (rank : 724)	NC score	0.075525 (rank : 595)
Query Neighborhood Hits	453	Target Neighborhood Hits	643	Shared Neighborhood Hits	37
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PHXR5_MOUSE
θ value	θ > 10 (rank : 725)	NC score	0.189989 (rank : 375)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	71
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PKD1_HUMAN
θ value	θ > 10 (rank : 726)	NC score	0.057988 (rank : 679)
Query Neighborhood Hits	453	Target Neighborhood Hits	387	Shared Neighborhood Hits	29
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

PP16A_MOUSE
θ value	θ > 10 (rank : 727)	NC score	0.050029 (rank : 772)
Query Neighborhood Hits	453	Target Neighborhood Hits	318	Shared Neighborhood Hits	9
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

PROP_HUMAN
θ value	θ > 10 (rank : 728)	NC score	0.050487 (rank : 761)
Query Neighborhood Hits	453	Target Neighborhood Hits	126	Shared Neighborhood Hits	33
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
θ value	θ > 10 (rank : 729)	NC score	0.063200 (rank : 645)
Query Neighborhood Hits	453	Target Neighborhood Hits	165	Shared Neighborhood Hits	43
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PSD10_HUMAN
θ value	θ > 10 (rank : 730)	NC score	0.057613 (rank : 681)
Query Neighborhood Hits	453	Target Neighborhood Hits	301	Shared Neighborhood Hits	8
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
θ value	θ > 10 (rank : 731)	NC score	0.056339 (rank : 693)
Query Neighborhood Hits	453	Target Neighborhood Hits	293	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

RECK_HUMAN
θ value	θ > 10 (rank : 732)	NC score	0.205356 (rank : 362)
Query Neighborhood Hits	453	Target Neighborhood Hits	189	Shared Neighborhood Hits	108
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 733)	NC score	0.164502 (rank : 403)
Query Neighborhood Hits	453	Target Neighborhood Hits	158	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

RN5A_HUMAN
θ value	θ > 10 (rank : 734)	NC score	0.050518 (rank : 760)
Query Neighborhood Hits	453	Target Neighborhood Hits	608	Shared Neighborhood Hits	11
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

RSPO2_HUMAN
θ value	θ > 10 (rank : 735)	NC score	0.050662 (rank : 759)
Query Neighborhood Hits	453	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO2_MOUSE
θ value	θ > 10 (rank : 736)	NC score	0.053041 (rank : 720)
Query Neighborhood Hits	453	Target Neighborhood Hits	88	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO3_MOUSE
θ value	θ > 10 (rank : 737)	NC score	0.082827 (rank : 565)
Query Neighborhood Hits	453	Target Neighborhood Hits	120	Shared Neighborhood Hits	59
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_HUMAN
θ value	θ > 10 (rank : 738)	NC score	0.076712 (rank : 591)
Query Neighborhood Hits	453	Target Neighborhood Hits	110	Shared Neighborhood Hits	60
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	θ > 10 (rank : 739)	NC score	0.062879 (rank : 647)
Query Neighborhood Hits	453	Target Neighborhood Hits	110	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SHAN1_HUMAN
θ value	θ > 10 (rank : 740)	NC score	0.060294 (rank : 667)
Query Neighborhood Hits	453	Target Neighborhood Hits	1041	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SORL_MOUSE
θ value	θ > 10 (rank : 741)	NC score	0.363664 (rank : 262)
Query Neighborhood Hits	453	Target Neighborhood Hits	439	Shared Neighborhood Hits	223
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SPIT1_HUMAN
θ value	θ > 10 (rank : 742)	NC score	0.052365 (rank : 732)
Query Neighborhood Hits	453	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPR2B_MOUSE
θ value	θ > 10 (rank : 743)	NC score	0.072888 (rank : 604)
Query Neighborhood Hits	453	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2E_HUMAN
θ value	θ > 10 (rank : 744)	NC score	0.050156 (rank : 771)
Query Neighborhood Hits	453	Target Neighborhood Hits	32	Shared Neighborhood Hits	15
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SPR2F_HUMAN
θ value	θ > 10 (rank : 745)	NC score	0.078908 (rank : 585)
Query Neighborhood Hits	453	Target Neighborhood Hits	33	Shared Neighborhood Hits	16
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2G_MOUSE
θ value	θ > 10 (rank : 746)	NC score	0.082631 (rank : 568)
Query Neighborhood Hits	453	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

ST14_HUMAN
θ value	θ > 10 (rank : 747)	NC score	0.163155 (rank : 404)
Query Neighborhood Hits	453	Target Neighborhood Hits	409	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
θ value	θ > 10 (rank : 748)	NC score	0.163006 (rank : 405)
Query Neighborhood Hits	453	Target Neighborhood Hits	419	Shared Neighborhood Hits	184
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

TECTA_HUMAN
θ value	θ > 10 (rank : 749)	NC score	0.182604 (rank : 383)
Query Neighborhood Hits	453	Target Neighborhood Hits	239	Shared Neighborhood Hits	163
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 750)	NC score	0.207036 (rank : 360)
Query Neighborhood Hits	453	Target Neighborhood Hits	244	Shared Neighborhood Hits	175
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TEFF2_HUMAN
θ value	θ > 10 (rank : 751)	NC score	0.313209 (rank : 299)
Query Neighborhood Hits	453	Target Neighborhood Hits	211	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 752)	NC score	0.315984 (rank : 294)
Query Neighborhood Hits	453	Target Neighborhood Hits	214	Shared Neighborhood Hits	141
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TGFA_MOUSE
θ value	θ > 10 (rank : 753)	NC score	0.082600 (rank : 570)
Query Neighborhood Hits	453	Target Neighborhood Hits	62	Shared Neighborhood Hits	49
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

THRB_HUMAN
θ value	θ > 10 (rank : 754)	NC score	0.057802 (rank : 680)
Query Neighborhood Hits	453	Target Neighborhood Hits	196	Shared Neighborhood Hits	33
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

THRB_MOUSE
θ value	θ > 10 (rank : 755)	NC score	0.056301 (rank : 695)
Query Neighborhood Hits	453	Target Neighborhood Hits	195	Shared Neighborhood Hits	33
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TMG1_HUMAN
θ value	θ > 10 (rank : 756)	NC score	0.093383 (rank : 535)
Query Neighborhood Hits	453	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

TMG2_HUMAN
θ value	θ > 10 (rank : 757)	NC score	0.071843 (rank : 609)
Query Neighborhood Hits	453	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	O14669	Gene names	PRRG2, PRGP2, TMG2
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2).

TMG2_MOUSE
θ value	θ > 10 (rank : 758)	NC score	0.070687 (rank : 617)
Query Neighborhood Hits	453	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R182, Q9EQI2	Gene names	Prrg2, N4wbp1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2) (NEDD4 WW domain-binding protein 1).

TMG3_HUMAN
θ value	θ > 10 (rank : 759)	NC score	0.084609 (rank : 561)
Query Neighborhood Hits	453	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD7, Q8N2N6	Gene names	PRRG3, TMG3
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

TMG3_MOUSE
θ value	θ > 10 (rank : 760)	NC score	0.083538 (rank : 564)
Query Neighborhood Hits	453	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PAQ9	Gene names	Prrg3, Gm368, Tmg3
Domain Architecture	No domain graphic available
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

TMG4_HUMAN
θ value	θ > 10 (rank : 761)	NC score	0.071714 (rank : 610)
Query Neighborhood Hits	453	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD6	Gene names	PRRG4, TMG4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

TMG4_MOUSE
θ value	θ > 10 (rank : 762)	NC score	0.064168 (rank : 639)
Query Neighborhood Hits	453	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BGN6, Q8BM25	Gene names	Prrg4, Tmg4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

TMPS6_HUMAN
θ value	θ > 10 (rank : 763)	NC score	0.123009 (rank : 464)
Query Neighborhood Hits	453	Target Neighborhood Hits	338	Shared Neighborhood Hits	137
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_MOUSE
θ value	θ > 10 (rank : 764)	NC score	0.115336 (rank : 479)
Query Neighborhood Hits	453	Target Neighborhood Hits	341	Shared Neighborhood Hits	137
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS7_HUMAN
θ value	θ > 10 (rank : 765)	NC score	0.079971 (rank : 580)
Query Neighborhood Hits	453	Target Neighborhood Hits	275	Shared Neighborhood Hits	87
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
θ value	θ > 10 (rank : 766)	NC score	0.079432 (rank : 582)
Query Neighborhood Hits	453	Target Neighborhood Hits	275	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS9_HUMAN
θ value	θ > 10 (rank : 767)	NC score	0.052989 (rank : 722)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TMPS9_MOUSE
θ value	θ > 10 (rank : 768)	NC score	0.052764 (rank : 725)
Query Neighborhood Hits	453	Target Neighborhood Hits	296	Shared Neighborhood Hits	68
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TNR11_HUMAN
θ value	θ > 10 (rank : 769)	NC score	0.081342 (rank : 577)
Query Neighborhood Hits	453	Target Neighborhood Hits	135	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
θ value	θ > 10 (rank : 770)	NC score	0.061028 (rank : 658)
Query Neighborhood Hits	453	Target Neighborhood Hits	121	Shared Neighborhood Hits	53
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR14_HUMAN
θ value	θ > 10 (rank : 771)	NC score	0.098886 (rank : 519)
Query Neighborhood Hits	453	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR16_MOUSE
θ value	θ > 10 (rank : 772)	NC score	0.123881 (rank : 463)
Query Neighborhood Hits	453	Target Neighborhood Hits	178	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR19_MOUSE
θ value	θ > 10 (rank : 773)	NC score	0.052080 (rank : 736)
Query Neighborhood Hits	453	Target Neighborhood Hits	100	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR22_MOUSE
θ value	θ > 10 (rank : 774)	NC score	0.070820 (rank : 615)
Query Neighborhood Hits	453	Target Neighborhood Hits	97	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR23_MOUSE
θ value	θ > 10 (rank : 775)	NC score	0.078981 (rank : 584)
Query Neighborhood Hits	453	Target Neighborhood Hits	114	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR25_HUMAN
θ value	θ > 10 (rank : 776)	NC score	0.156762 (rank : 410)
Query Neighborhood Hits	453	Target Neighborhood Hits	172	Shared Neighborhood Hits	76
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR26_MOUSE
θ value	θ > 10 (rank : 777)	NC score	0.060117 (rank : 668)
Query Neighborhood Hits	453	Target Neighborhood Hits	106	Shared Neighborhood Hits	55
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR3_MOUSE
θ value	θ > 10 (rank : 778)	NC score	0.058556 (rank : 675)
Query Neighborhood Hits	453	Target Neighborhood Hits	113	Shared Neighborhood Hits	51
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR4_HUMAN
θ value	θ > 10 (rank : 779)	NC score	0.098566 (rank : 520)
Query Neighborhood Hits	453	Target Neighborhood Hits	152	Shared Neighborhood Hits	62
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR4_MOUSE
θ value	θ > 10 (rank : 780)	NC score	0.106974 (rank : 495)
Query Neighborhood Hits	453	Target Neighborhood Hits	137	Shared Neighborhood Hits	69
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR5_HUMAN
θ value	θ > 10 (rank : 781)	NC score	0.052761 (rank : 726)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	48
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR6B_HUMAN
θ value	θ > 10 (rank : 782)	NC score	0.050234 (rank : 768)
Query Neighborhood Hits	453	Target Neighborhood Hits	103	Shared Neighborhood Hits	41
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR6_MOUSE
θ value	θ > 10 (rank : 783)	NC score	0.060002 (rank : 669)
Query Neighborhood Hits	453	Target Neighborhood Hits	99	Shared Neighborhood Hits	43
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR7_HUMAN
θ value	θ > 10 (rank : 784)	NC score	0.099979 (rank : 516)
Query Neighborhood Hits	453	Target Neighborhood Hits	120	Shared Neighborhood Hits	61
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR7_MOUSE
θ value	θ > 10 (rank : 785)	NC score	0.063276 (rank : 644)
Query Neighborhood Hits	453	Target Neighborhood Hits	112	Shared Neighborhood Hits	46
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR8_HUMAN
θ value	θ > 10 (rank : 786)	NC score	0.076043 (rank : 593)
Query Neighborhood Hits	453	Target Neighborhood Hits	198	Shared Neighborhood Hits	72
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR8_MOUSE
θ value	θ > 10 (rank : 787)	NC score	0.093182 (rank : 536)
Query Neighborhood Hits	453	Target Neighborhood Hits	208	Shared Neighborhood Hits	71
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR9_HUMAN
θ value	θ > 10 (rank : 788)	NC score	0.109214 (rank : 490)
Query Neighborhood Hits	453	Target Neighborhood Hits	166	Shared Neighborhood Hits	69
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR9_MOUSE
θ value	θ > 10 (rank : 789)	NC score	0.079306 (rank : 583)
Query Neighborhood Hits	453	Target Neighborhood Hits	137	Shared Neighborhood Hits	64
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TSG6_HUMAN
θ value	θ > 10 (rank : 790)	NC score	0.094828 (rank : 532)
Query Neighborhood Hits	453	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 791)	NC score	0.094850 (rank : 531)
Query Neighborhood Hits	453	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

VEGFC_HUMAN
θ value	θ > 10 (rank : 792)	NC score	0.138825 (rank : 435)
Query Neighborhood Hits	453	Target Neighborhood Hits	128	Shared Neighborhood Hits	91
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VEGFC_MOUSE
θ value	θ > 10 (rank : 793)	NC score	0.126250 (rank : 457)
Query Neighborhood Hits	453	Target Neighborhood Hits	119	Shared Neighborhood Hits	86
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

WFDC3_HUMAN
θ value	θ > 10 (rank : 794)	NC score	0.127908 (rank : 455)
Query Neighborhood Hits	453	Target Neighborhood Hits	138	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

WISP2_HUMAN
θ value	θ > 10 (rank : 795)	NC score	0.056731 (rank : 690)
Query Neighborhood Hits	453	Target Neighborhood Hits	126	Shared Neighborhood Hits	35
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

XLKD1_HUMAN
θ value	θ > 10 (rank : 796)	NC score	0.054678 (rank : 710)
Query Neighborhood Hits	453	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y5Y7, Q8TC18, Q9UNF4	Gene names	XLKD1, CRSBP1, HAR
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Hyaluronic acid receptor) (Extracellular link domain-containing protein 1).

XLKD1_MOUSE
θ value	θ > 10 (rank : 797)	NC score	0.055698 (rank : 701)
Query Neighborhood Hits	453	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BHC0, Q3TUC1, Q99NE4	Gene names	Xlkd1, Crsbp1
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Extracellular link domain-containing protein 1).

XLRS1_HUMAN
θ value	θ > 10 (rank : 798)	NC score	0.062488 (rank : 649)
Query Neighborhood Hits	453	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

XLRS1_MOUSE
θ value	θ > 10 (rank : 799)	NC score	0.063783 (rank : 641)
Query Neighborhood Hits	453	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

Hits sorted by NC score

CRUM2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	453	Target Neighborhood Hits	453	Shared Neighborhood Hits	453
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CRUM1_MOUSE
NC score	0.981995 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	453	Target Neighborhood Hits	444	Shared Neighborhood Hits	379
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM1_HUMAN
NC score	0.980167 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	453	Target Neighborhood Hits	457	Shared Neighborhood Hits	384
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

DNER_HUMAN
NC score	0.957909 (rank : 4)	θ value	2.4834e-66 (rank : 16)
Query Neighborhood Hits	453	Target Neighborhood Hits	460	Shared Neighborhood Hits	368
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
NC score	0.957683 (rank : 5)	θ value	2.56992e-63 (rank : 19)
Query Neighborhood Hits	453	Target Neighborhood Hits	413	Shared Neighborhood Hits	359
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

JAG2_HUMAN
NC score	0.954587 (rank : 6)	θ value	1.89267e-82 (rank : 12)
Query Neighborhood Hits	453	Target Neighborhood Hits	491	Shared Neighborhood Hits	388
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
NC score	0.953965 (rank : 7)	θ value	1.77149e-80 (rank : 13)
Query Neighborhood Hits	453	Target Neighborhood Hits	504	Shared Neighborhood Hits	382
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

DLL1_MOUSE
NC score	0.953893 (rank : 8)	θ value	1.15359e-63 (rank : 18)
Query Neighborhood Hits	453	Target Neighborhood Hits	456	Shared Neighborhood Hits	382
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL1_HUMAN
NC score	0.953640 (rank : 9)	θ value	3.58603e-65 (rank : 17)
Query Neighborhood Hits	453	Target Neighborhood Hits	455	Shared Neighborhood Hits	371
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

JAG1_HUMAN
NC score	0.951994 (rank : 10)	θ value	1.14825e-79 (rank : 15)
Query Neighborhood Hits	453	Target Neighborhood Hits	514	Shared Neighborhood Hits	392
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
NC score	0.951373 (rank : 11)	θ value	2.31364e-80 (rank : 14)
Query Neighborhood Hits	453	Target Neighborhood Hits	518	Shared Neighborhood Hits	386
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

DLL4_HUMAN
NC score	0.950717 (rank : 12)	θ value	2.7521e-57 (rank : 21)
Query Neighborhood Hits	453	Target Neighborhood Hits	435	Shared Neighborhood Hits	363
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
NC score	0.949265 (rank : 13)	θ value	1.11734e-58 (rank : 20)
Query Neighborhood Hits	453	Target Neighborhood Hits	440	Shared Neighborhood Hits	364
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL3_MOUSE
NC score	0.945746 (rank : 14)	θ value	7.03111e-45 (rank : 27)
Query Neighborhood Hits	453	Target Neighborhood Hits	399	Shared Neighborhood Hits	352
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL3_HUMAN
NC score	0.943679 (rank : 15)	θ value	4.2656e-42 (rank : 33)
Query Neighborhood Hits	453	Target Neighborhood Hits	419	Shared Neighborhood Hits	355
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

EGFL9_HUMAN
NC score	0.943674 (rank : 16)	θ value	9.50281e-42 (rank : 34)
Query Neighborhood Hits	453	Target Neighborhood Hits	365	Shared Neighborhood Hits	334
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
NC score	0.942307 (rank : 17)	θ value	2.50074e-42 (rank : 32)
Query Neighborhood Hits	453	Target Neighborhood Hits	379	Shared Neighborhood Hits	338
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

DLK_HUMAN
NC score	0.941052 (rank : 18)	θ value	1.6774e-38 (rank : 38)
Query Neighborhood Hits	453	Target Neighborhood Hits	401	Shared Neighborhood Hits	352
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
NC score	0.939703 (rank : 19)	θ value	2.96089e-35 (rank : 41)
Query Neighborhood Hits	453	Target Neighborhood Hits	374	Shared Neighborhood Hits	340
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

NOTC1_MOUSE
NC score	0.885255 (rank : 20)	θ value	4.80189e-94 (rank : 4)
Query Neighborhood Hits	453	Target Neighborhood Hits	916	Shared Neighborhood Hits	412
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

MEGF6_HUMAN
NC score	0.873833 (rank : 21)	θ value	1.79631e-32 (rank : 48)
Query Neighborhood Hits	453	Target Neighborhood Hits	671	Shared Neighborhood Hits	400
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

LTBP4_MOUSE
NC score	0.870117 (rank : 22)	θ value	1.46607e-42 (rank : 31)
Query Neighborhood Hits	453	Target Neighborhood Hits	607	Shared Neighborhood Hits	348
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

NOTC2_MOUSE
NC score	0.860819 (rank : 23)	θ value	8.19079e-94 (rank : 5)
Query Neighborhood Hits	453	Target Neighborhood Hits	1069	Shared Neighborhood Hits	409
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC1_HUMAN
NC score	0.860384 (rank : 24)	θ value	5.86991e-92 (rank : 7)
Query Neighborhood Hits	453	Target Neighborhood Hits	906	Shared Neighborhood Hits	406
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_MOUSE
NC score	0.860162 (rank : 25)	θ value	8.47616e-91 (rank : 8)
Query Neighborhood Hits	453	Target Neighborhood Hits	975	Shared Neighborhood Hits	412
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
NC score	0.859933 (rank : 26)	θ value	1.88829e-90 (rank : 10)
Query Neighborhood Hits	453	Target Neighborhood Hits	1062	Shared Neighborhood Hits	413
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC2_HUMAN
NC score	0.857024 (rank : 27)	θ value	4.49445e-92 (rank : 6)
Query Neighborhood Hits	453	Target Neighborhood Hits	1113	Shared Neighborhood Hits	416
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

FBN3_HUMAN
NC score	0.849323 (rank : 28)	θ value	2.96089e-35 (rank : 43)
Query Neighborhood Hits	453	Target Neighborhood Hits	543	Shared Neighborhood Hits	370
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LTBP2_MOUSE
NC score	0.846120 (rank : 29)	θ value	1.28732e-30 (rank : 54)
Query Neighborhood Hits	453	Target Neighborhood Hits	617	Shared Neighborhood Hits	354
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_HUMAN
NC score	0.845466 (rank : 30)	θ value	1.79631e-32 (rank : 47)
Query Neighborhood Hits	453	Target Neighborhood Hits	552	Shared Neighborhood Hits	360
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
NC score	0.845137 (rank : 31)	θ value	4.13158e-37 (rank : 39)
Query Neighborhood Hits	453	Target Neighborhood Hits	502	Shared Neighborhood Hits	345
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NOTC4_HUMAN
NC score	0.844660 (rank : 32)	θ value	6.71607e-88 (rank : 11)
Query Neighborhood Hits	453	Target Neighborhood Hits	905	Shared Neighborhood Hits	416
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

FBN1_MOUSE
NC score	0.844062 (rank : 33)	θ value	2.96089e-35 (rank : 42)
Query Neighborhood Hits	453	Target Neighborhood Hits	563	Shared Neighborhood Hits	374
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_HUMAN
NC score	0.843375 (rank : 34)	θ value	1.46948e-34 (rank : 45)
Query Neighborhood Hits	453	Target Neighborhood Hits	557	Shared Neighborhood Hits	374
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_MOUSE
NC score	0.843314 (rank : 35)	θ value	4.00176e-32 (rank : 52)
Query Neighborhood Hits	453	Target Neighborhood Hits	549	Shared Neighborhood Hits	376
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

NOTC4_MOUSE
NC score	0.843148 (rank : 36)	θ value	1.10702e-90 (rank : 9)
Query Neighborhood Hits	453	Target Neighborhood Hits	872	Shared Neighborhood Hits	414
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NELL1_HUMAN
NC score	0.843056 (rank : 37)	θ value	1.29031e-22 (rank : 70)
Query Neighborhood Hits	453	Target Neighborhood Hits	451	Shared Neighborhood Hits	333
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

FBN2_HUMAN
NC score	0.841917 (rank : 38)	θ value	4.00176e-32 (rank : 51)
Query Neighborhood Hits	453	Target Neighborhood Hits	560	Shared Neighborhood Hits	378
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

NELL2_MOUSE
NC score	0.840538 (rank : 39)	θ value	1.12775e-26 (rank : 62)
Query Neighborhood Hits	453	Target Neighborhood Hits	436	Shared Neighborhood Hits	335
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

WIF1_HUMAN
NC score	0.839901 (rank : 40)	θ value	1.80466e-16 (rank : 105)
Query Neighborhood Hits	453	Target Neighborhood Hits	392	Shared Neighborhood Hits	327
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

LTBP3_MOUSE
NC score	0.838900 (rank : 41)	θ value	4.72714e-33 (rank : 46)
Query Neighborhood Hits	453	Target Neighborhood Hits	475	Shared Neighborhood Hits	338
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NELL2_HUMAN
NC score	0.838670 (rank : 42)	θ value	4.28545e-26 (rank : 63)
Query Neighborhood Hits	453	Target Neighborhood Hits	449	Shared Neighborhood Hits	335
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

WIF1_MOUSE
NC score	0.834280 (rank : 43)	θ value	6.85773e-16 (rank : 109)
Query Neighborhood Hits	453	Target Neighborhood Hits	393	Shared Neighborhood Hits	322
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

LTB1L_MOUSE
NC score	0.825587 (rank : 44)	θ value	1.85889e-29 (rank : 55)
Query Neighborhood Hits	453	Target Neighborhood Hits	514	Shared Neighborhood Hits	356
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
NC score	0.825099 (rank : 45)	θ value	1.85889e-29 (rank : 56)
Query Neighborhood Hits	453	Target Neighborhood Hits	479	Shared Neighborhood Hits	340
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.823126 (rank : 46)	θ value	2.96777e-27 (rank : 60)
Query Neighborhood Hits	453	Target Neighborhood Hits	553	Shared Neighborhood Hits	344
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.822671 (rank : 47)	θ value	2.96777e-27 (rank : 61)
Query Neighborhood Hits	453	Target Neighborhood Hits	502	Shared Neighborhood Hits	343
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FBLN2_HUMAN
NC score	0.810268 (rank : 48)	θ value	6.82597e-32 (rank : 53)
Query Neighborhood Hits	453	Target Neighborhood Hits	392	Shared Neighborhood Hits	269
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

C1QR1_HUMAN
NC score	0.807693 (rank : 49)	θ value	8.10077e-17 (rank : 99)
Query Neighborhood Hits	453	Target Neighborhood Hits	493	Shared Neighborhood Hits	292
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
NC score	0.807366 (rank : 50)	θ value	1.5773e-20 (rank : 73)
Query Neighborhood Hits	453	Target Neighborhood Hits	342	Shared Neighborhood Hits	277
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

GAS6_MOUSE
NC score	0.803674 (rank : 51)	θ value	1.058e-16 (rank : 100)
Query Neighborhood Hits	453	Target Neighborhood Hits	343	Shared Neighborhood Hits	296
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

SREC_HUMAN
NC score	0.801986 (rank : 52)	θ value	1.09232e-21 (rank : 71)
Query Neighborhood Hits	453	Target Neighborhood Hits	645	Shared Neighborhood Hits	341
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

FBLN2_MOUSE
NC score	0.801603 (rank : 53)	θ value	2.59989e-23 (rank : 66)
Query Neighborhood Hits	453	Target Neighborhood Hits	505	Shared Neighborhood Hits	282
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

GAS6_HUMAN
NC score	0.800304 (rank : 54)	θ value	2.5182e-18 (rank : 95)
Query Neighborhood Hits	453	Target Neighborhood Hits	348	Shared Neighborhood Hits	292
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

FBLN1_MOUSE
NC score	0.798832 (rank : 55)	θ value	1.33217e-27 (rank : 59)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	269
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN1_HUMAN
NC score	0.798338 (rank : 56)	θ value	7.80994e-28 (rank : 58)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	273
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

SREC2_MOUSE
NC score	0.796991 (rank : 57)	θ value	9.87957e-23 (rank : 69)
Query Neighborhood Hits	453	Target Neighborhood Hits	605	Shared Neighborhood Hits	320
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

PROS_HUMAN
NC score	0.796101 (rank : 58)	θ value	5.99374e-20 (rank : 79)
Query Neighborhood Hits	453	Target Neighborhood Hits	340	Shared Neighborhood Hits	297
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
NC score	0.791057 (rank : 59)	θ value	3.40345e-15 (rank : 117)
Query Neighborhood Hits	453	Target Neighborhood Hits	330	Shared Neighborhood Hits	294
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SREC2_HUMAN
NC score	0.790987 (rank : 60)	θ value	1.80048e-24 (rank : 64)
Query Neighborhood Hits	453	Target Neighborhood Hits	645	Shared Neighborhood Hits	318
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

STAB2_HUMAN
NC score	0.782546 (rank : 61)	θ value	1.86753e-13 (rank : 128)
Query Neighborhood Hits	453	Target Neighborhood Hits	534	Shared Neighborhood Hits	346
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

SCUB3_HUMAN
NC score	0.782331 (rank : 62)	θ value	1.02238e-19 (rank : 82)
Query Neighborhood Hits	453	Target Neighborhood Hits	428	Shared Neighborhood Hits	279
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

STAB1_HUMAN
NC score	0.781998 (rank : 63)	θ value	1.16975e-15 (rank : 112)
Query Neighborhood Hits	453	Target Neighborhood Hits	546	Shared Neighborhood Hits	350
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

FBLN4_HUMAN
NC score	0.781083 (rank : 64)	θ value	1.74391e-19 (rank : 83)
Query Neighborhood Hits	453	Target Neighborhood Hits	278	Shared Neighborhood Hits	242
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

SCUB3_MOUSE
NC score	0.780286 (rank : 65)	θ value	1.74391e-19 (rank : 84)
Query Neighborhood Hits	453	Target Neighborhood Hits	442	Shared Neighborhood Hits	282
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

STAB2_MOUSE
NC score	0.778586 (rank : 66)	θ value	2.88119e-14 (rank : 124)
Query Neighborhood Hits	453	Target Neighborhood Hits	528	Shared Neighborhood Hits	349
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

STAB1_MOUSE
NC score	0.778451 (rank : 67)	θ value	1.92812e-18 (rank : 94)
Query Neighborhood Hits	453	Target Neighborhood Hits	566	Shared Neighborhood Hits	351
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

FBLN4_MOUSE
NC score	0.774634 (rank : 68)	θ value	5.07402e-19 (rank : 90)
Query Neighborhood Hits	453	Target Neighborhood Hits	270	Shared Neighborhood Hits	235
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

EGFL7_HUMAN
NC score	0.772530 (rank : 69)	θ value	1.53129e-07 (rank : 180)
Query Neighborhood Hits	453	Target Neighborhood Hits	325	Shared Neighborhood Hits	278
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

CUBN_MOUSE
NC score	0.771963 (rank : 70)	θ value	9.18288e-45 (rank : 28)
Query Neighborhood Hits	453	Target Neighborhood Hits	477	Shared Neighborhood Hits	341
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

FBLN5_HUMAN
NC score	0.771162 (rank : 71)	θ value	8.95645e-16 (rank : 110)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	272
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

CUBN_HUMAN
NC score	0.768175 (rank : 72)	θ value	2.41655e-45 (rank : 26)
Query Neighborhood Hits	453	Target Neighborhood Hits	482	Shared Neighborhood Hits	345
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

FBLN5_MOUSE
NC score	0.767486 (rank : 73)	θ value	5.25075e-16 (rank : 106)
Query Neighborhood Hits	453	Target Neighborhood Hits	317	Shared Neighborhood Hits	257
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

TRBM_HUMAN
NC score	0.766073 (rank : 74)	θ value	7.09661e-13 (rank : 130)
Query Neighborhood Hits	453	Target Neighborhood Hits	339	Shared Neighborhood Hits	263
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

EGFL7_MOUSE
NC score	0.762273 (rank : 75)	θ value	4.45536e-07 (rank : 188)
Query Neighborhood Hits	453	Target Neighborhood Hits	287	Shared Neighborhood Hits	255
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

FBLN3_HUMAN
NC score	0.761475 (rank : 76)	θ value	3.63628e-17 (rank : 98)
Query Neighborhood Hits	453	Target Neighborhood Hits	293	Shared Neighborhood Hits	249
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

EGFL8_MOUSE
NC score	0.758214 (rank : 77)	θ value	1.25267e-09 (rank : 150)
Query Neighborhood Hits	453	Target Neighborhood Hits	266	Shared Neighborhood Hits	246
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

FBLN3_MOUSE
NC score	0.752965 (rank : 78)	θ value	2.20605e-14 (rank : 123)
Query Neighborhood Hits	453	Target Neighborhood Hits	279	Shared Neighborhood Hits	237
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

TRBM_MOUSE
NC score	0.750579 (rank : 79)	θ value	2.79066e-09 (rank : 159)
Query Neighborhood Hits	453	Target Neighborhood Hits	361	Shared Neighborhood Hits	267
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

EGFL8_HUMAN
NC score	0.748691 (rank : 80)	θ value	1.17247e-07 (rank : 179)
Query Neighborhood Hits	453	Target Neighborhood Hits	270	Shared Neighborhood Hits	243
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

AGRIN_HUMAN
NC score	0.743997 (rank : 81)	θ value	3.28887e-18 (rank : 96)
Query Neighborhood Hits	453	Target Neighborhood Hits	582	Shared Neighborhood Hits	341
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

CREL1_HUMAN
NC score	0.740944 (rank : 82)	θ value	1.69304e-06 (rank : 201)
Query Neighborhood Hits	453	Target Neighborhood Hits	441	Shared Neighborhood Hits	263
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EDIL3_MOUSE
NC score	0.738718 (rank : 83)	θ value	2.06002e-20 (rank : 76)
Query Neighborhood Hits	453	Target Neighborhood Hits	317	Shared Neighborhood Hits	279
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

UROM_HUMAN
NC score	0.732900 (rank : 84)	θ value	4.59992e-12 (rank : 136)
Query Neighborhood Hits	453	Target Neighborhood Hits	284	Shared Neighborhood Hits	249
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

EDIL3_HUMAN
NC score	0.728405 (rank : 85)	θ value	1.5773e-20 (rank : 75)
Query Neighborhood Hits	453	Target Neighborhood Hits	292	Shared Neighborhood Hits	259
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

NID2_HUMAN
NC score	0.728318 (rank : 86)	θ value	9.26847e-13 (rank : 131)
Query Neighborhood Hits	453	Target Neighborhood Hits	456	Shared Neighborhood Hits	278
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
NC score	0.727099 (rank : 87)	θ value	1.99529e-15 (rank : 113)
Query Neighborhood Hits	453	Target Neighborhood Hits	338	Shared Neighborhood Hits	269
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

TSP4_MOUSE
NC score	0.724523 (rank : 88)	θ value	3.88503e-19 (rank : 88)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	250
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

CREL1_MOUSE
NC score	0.724396 (rank : 89)	θ value	4.92598e-06 (rank : 210)
Query Neighborhood Hits	453	Target Neighborhood Hits	524	Shared Neighborhood Hits	260
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EGF_MOUSE
NC score	0.722531 (rank : 90)	θ value	3.76295e-14 (rank : 125)
Query Neighborhood Hits	453	Target Neighborhood Hits	358	Shared Neighborhood Hits	299
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

TSP4_HUMAN
NC score	0.722370 (rank : 91)	θ value	3.88503e-19 (rank : 87)
Query Neighborhood Hits	453	Target Neighborhood Hits	277	Shared Neighborhood Hits	248
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

SUSD1_HUMAN
NC score	0.719784 (rank : 92)	θ value	3.64472e-09 (rank : 161)
Query Neighborhood Hits	453	Target Neighborhood Hits	285	Shared Neighborhood Hits	225
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

UROM_MOUSE
NC score	0.718265 (rank : 93)	θ value	1.25267e-09 (rank : 153)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	245
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

NID1_HUMAN
NC score	0.716614 (rank : 94)	θ value	4.16044e-13 (rank : 129)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	270
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
NC score	0.716614 (rank : 95)	θ value	9.90251e-15 (rank : 121)
Query Neighborhood Hits	453	Target Neighborhood Hits	335	Shared Neighborhood Hits	262
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

MEGF8_HUMAN
NC score	0.709505 (rank : 96)	θ value	5.08577e-11 (rank : 142)
Query Neighborhood Hits	453	Target Neighborhood Hits	528	Shared Neighborhood Hits	325
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

SLIT1_MOUSE
NC score	0.705572 (rank : 97)	θ value	1.32601e-43 (rank : 30)
Query Neighborhood Hits	453	Target Neighborhood Hits	715	Shared Neighborhood Hits	358
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

MEGF8_MOUSE
NC score	0.704210 (rank : 98)	θ value	3.89403e-11 (rank : 141)
Query Neighborhood Hits	453	Target Neighborhood Hits	520	Shared Neighborhood Hits	318
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

SLIT1_HUMAN
NC score	0.703976 (rank : 99)	θ value	1.32601e-43 (rank : 29)
Query Neighborhood Hits	453	Target Neighborhood Hits	700	Shared Neighborhood Hits	354
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

EMR1_HUMAN
NC score	0.696983 (rank : 100)	θ value	5.07402e-19 (rank : 89)
Query Neighborhood Hits	453	Target Neighborhood Hits	382	Shared Neighborhood Hits	263
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

SLIT2_HUMAN
NC score	0.696775 (rank : 101)	θ value	3.98324e-48 (rank : 23)
Query Neighborhood Hits	453	Target Neighborhood Hits	708	Shared Neighborhood Hits	359
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

MATN2_HUMAN
NC score	0.693987 (rank : 102)	θ value	4.44505e-15 (rank : 118)
Query Neighborhood Hits	453	Target Neighborhood Hits	365	Shared Neighborhood Hits	254
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

COMP_MOUSE
NC score	0.691947 (rank : 103)	θ value	1.74796e-11 (rank : 140)
Query Neighborhood Hits	453	Target Neighborhood Hits	290	Shared Neighborhood Hits	243
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

SLIT2_MOUSE
NC score	0.691476 (rank : 104)	θ value	1.788e-48 (rank : 22)
Query Neighborhood Hits	453	Target Neighborhood Hits	684	Shared Neighborhood Hits	347
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

EGF_HUMAN
NC score	0.685245 (rank : 105)	θ value	7.84624e-12 (rank : 138)
Query Neighborhood Hits	453	Target Neighborhood Hits	343	Shared Neighborhood Hits	280
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

MATN2_MOUSE
NC score	0.680467 (rank : 106)	θ value	1.42992e-13 (rank : 127)
Query Neighborhood Hits	453	Target Neighborhood Hits	356	Shared Neighborhood Hits	249
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

SLIT3_MOUSE
NC score	0.679979 (rank : 107)	θ value	1.15895e-47 (rank : 24)
Query Neighborhood Hits	453	Target Neighborhood Hits	700	Shared Neighborhood Hits	350
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SLIT3_HUMAN
NC score	0.675118 (rank : 108)	θ value	2.18568e-46 (rank : 25)
Query Neighborhood Hits	453	Target Neighborhood Hits	682	Shared Neighborhood Hits	348
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

LRP1_HUMAN
NC score	0.674543 (rank : 109)	θ value	4.58923e-20 (rank : 78)
Query Neighborhood Hits	453	Target Neighborhood Hits	617	Shared Neighborhood Hits	381
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

EMR2_HUMAN
NC score	0.672271 (rank : 110)	θ value	2.60593e-15 (rank : 115)
Query Neighborhood Hits	453	Target Neighborhood Hits	345	Shared Neighborhood Hits	250
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

LRP1B_HUMAN
NC score	0.669151 (rank : 111)	θ value	4.58923e-20 (rank : 77)
Query Neighborhood Hits	453	Target Neighborhood Hits	602	Shared Neighborhood Hits	384
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
NC score	0.665940 (rank : 112)	θ value	1.47631e-18 (rank : 91)
Query Neighborhood Hits	453	Target Neighborhood Hits	606	Shared Neighborhood Hits	386
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

EMR1_MOUSE
NC score	0.664883 (rank : 113)	θ value	2.27762e-19 (rank : 85)
Query Neighborhood Hits	453	Target Neighborhood Hits	349	Shared Neighborhood Hits	240
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

COMP_HUMAN
NC score	0.664059 (rank : 114)	θ value	8.67504e-11 (rank : 143)
Query Neighborhood Hits	453	Target Neighborhood Hits	258	Shared Neighborhood Hits	227
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CD97_HUMAN
NC score	0.663006 (rank : 115)	θ value	2.60593e-15 (rank : 114)
Query Neighborhood Hits	453	Target Neighborhood Hits	353	Shared Neighborhood Hits	252
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

TENA_HUMAN
NC score	0.659855 (rank : 116)	θ value	3.39556e-23 (rank : 67)
Query Neighborhood Hits	453	Target Neighborhood Hits	631	Shared Neighborhood Hits	334
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENX_HUMAN
NC score	0.657996 (rank : 117)	θ value	3.50572e-28 (rank : 57)
Query Neighborhood Hits	453	Target Neighborhood Hits	789	Shared Neighborhood Hits	335
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TSP3_MOUSE
NC score	0.655964 (rank : 118)	θ value	8.38298e-14 (rank : 126)
Query Neighborhood Hits	453	Target Neighborhood Hits	247	Shared Neighborhood Hits	218
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TENA_MOUSE
NC score	0.654499 (rank : 119)	θ value	4.43474e-23 (rank : 68)
Query Neighborhood Hits	453	Target Neighborhood Hits	596	Shared Neighborhood Hits	323
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

LAMA5_MOUSE
NC score	0.652284 (rank : 120)	θ value	1.38178e-16 (rank : 103)
Query Neighborhood Hits	453	Target Neighborhood Hits	828	Shared Neighborhood Hits	333
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

TSP3_HUMAN
NC score	0.646575 (rank : 121)	θ value	9.26847e-13 (rank : 132)
Query Neighborhood Hits	453	Target Neighborhood Hits	250	Shared Neighborhood Hits	213
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

LAMA5_HUMAN
NC score	0.637617 (rank : 122)	θ value	2.27762e-19 (rank : 86)
Query Neighborhood Hits	453	Target Neighborhood Hits	976	Shared Neighborhood Hits	334
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MEGF9_HUMAN
NC score	0.623267 (rank : 123)	θ value	0.00020696 (rank : 239)
Query Neighborhood Hits	453	Target Neighborhood Hits	557	Shared Neighborhood Hits	267
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

KRA53_HUMAN
NC score	0.623222 (rank : 124)	θ value	0.62314 (rank : 341)
Query Neighborhood Hits	453	Target Neighborhood Hits	331	Shared Neighborhood Hits	222
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA51_HUMAN
NC score	0.622972 (rank : 125)	θ value	0.00665767 (rank : 267)
Query Neighborhood Hits	453	Target Neighborhood Hits	288	Shared Neighborhood Hits	199
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LAMA1_HUMAN
NC score	0.620394 (rank : 126)	θ value	7.82807e-20 (rank : 81)
Query Neighborhood Hits	453	Target Neighborhood Hits	804	Shared Neighborhood Hits	308
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB2_HUMAN
NC score	0.619492 (rank : 127)	θ value	1.92812e-18 (rank : 93)
Query Neighborhood Hits	453	Target Neighborhood Hits	692	Shared Neighborhood Hits	285
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMA1_MOUSE
NC score	0.618940 (rank : 128)	θ value	5.25075e-16 (rank : 107)
Query Neighborhood Hits	453	Target Neighborhood Hits	838	Shared Neighborhood Hits	313
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB2_MOUSE
NC score	0.611008 (rank : 129)	θ value	1.80466e-16 (rank : 104)
Query Neighborhood Hits	453	Target Neighborhood Hits	722	Shared Neighborhood Hits	283
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

NAGPA_HUMAN
NC score	0.603373 (rank : 130)	θ value	0.00102713 (rank : 247)
Query Neighborhood Hits	453	Target Neighborhood Hits	282	Shared Neighborhood Hits	225
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

LAMC3_MOUSE
NC score	0.602161 (rank : 131)	θ value	8.11959e-09 (rank : 163)
Query Neighborhood Hits	453	Target Neighborhood Hits	624	Shared Neighborhood Hits	286
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

PROZ_MOUSE
NC score	0.600914 (rank : 132)	θ value	1.06045e-08 (rank : 165)
Query Neighborhood Hits	453	Target Neighborhood Hits	410	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

CD248_MOUSE
NC score	0.599191 (rank : 133)	θ value	4.92598e-06 (rank : 208)
Query Neighborhood Hits	453	Target Neighborhood Hits	578	Shared Neighborhood Hits	219
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CSPG2_MOUSE
NC score	0.598952 (rank : 134)	θ value	1.92812e-18 (rank : 92)
Query Neighborhood Hits	453	Target Neighborhood Hits	711	Shared Neighborhood Hits	281
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

PROZ_HUMAN
NC score	0.595357 (rank : 135)	θ value	1.25267e-09 (rank : 152)
Query Neighborhood Hits	453	Target Neighborhood Hits	422	Shared Neighborhood Hits	265
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

LAMC3_HUMAN
NC score	0.595131 (rank : 136)	θ value	1.63604e-09 (rank : 154)
Query Neighborhood Hits	453	Target Neighborhood Hits	588	Shared Neighborhood Hits	289
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

CSPG2_HUMAN
NC score	0.594813 (rank : 137)	θ value	4.29542e-18 (rank : 97)
Query Neighborhood Hits	453	Target Neighborhood Hits	681	Shared Neighborhood Hits	282
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG3_MOUSE
NC score	0.594115 (rank : 138)	θ value	1.5773e-20 (rank : 74)
Query Neighborhood Hits	453	Target Neighborhood Hits	657	Shared Neighborhood Hits	276
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

NAGPA_MOUSE
NC score	0.592108 (rank : 139)	θ value	0.00175202 (rank : 252)
Query Neighborhood Hits	453	Target Neighborhood Hits	308	Shared Neighborhood Hits	247
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

ZAN_MOUSE
NC score	0.591710 (rank : 140)	θ value	9.92553e-07 (rank : 197)
Query Neighborhood Hits	453	Target Neighborhood Hits	808	Shared Neighborhood Hits	350
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

LAMC2_MOUSE
NC score	0.590780 (rank : 141)	θ value	6.87365e-08 (rank : 175)
Query Neighborhood Hits	453	Target Neighborhood Hits	614	Shared Neighborhood Hits	274
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

CD248_HUMAN
NC score	0.589628 (rank : 142)	θ value	1.87187e-05 (rank : 219)
Query Neighborhood Hits	453	Target Neighborhood Hits	679	Shared Neighborhood Hits	233
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

KRA58_HUMAN
NC score	0.589584 (rank : 143)	θ value	0.125558 (rank : 304)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	211
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

CSPG3_HUMAN
NC score	0.585399 (rank : 144)	θ value	7.82807e-20 (rank : 80)
Query Neighborhood Hits	453	Target Neighborhood Hits	676	Shared Neighborhood Hits	264
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

MEGF9_MOUSE
NC score	0.579767 (rank : 145)	θ value	0.0193708 (rank : 283)
Query Neighborhood Hits	453	Target Neighborhood Hits	896	Shared Neighborhood Hits	239
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMA2_HUMAN
NC score	0.577136 (rank : 146)	θ value	6.85773e-16 (rank : 108)
Query Neighborhood Hits	453	Target Neighborhood Hits	1092	Shared Neighborhood Hits	300
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

HHIP_HUMAN
NC score	0.574963 (rank : 147)	θ value	0.00509761 (rank : 263)
Query Neighborhood Hits	453	Target Neighborhood Hits	249	Shared Neighborhood Hits	205
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KR107_HUMAN
NC score	0.574110 (rank : 148)	θ value	0.00020696 (rank : 236)
Query Neighborhood Hits	453	Target Neighborhood Hits	330	Shared Neighborhood Hits	211
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

CD97_MOUSE
NC score	0.573435 (rank : 149)	θ value	7.59969e-07 (rank : 190)
Query Neighborhood Hits	453	Target Neighborhood Hits	295	Shared Neighborhood Hits	210
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

LDLR_HUMAN
NC score	0.571980 (rank : 150)	θ value	3.52202e-12 (rank : 135)
Query Neighborhood Hits	453	Target Neighborhood Hits	375	Shared Neighborhood Hits	284
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MATN4_HUMAN
NC score	0.571250 (rank : 151)	θ value	0.00020696 (rank : 238)
Query Neighborhood Hits	453	Target Neighborhood Hits	287	Shared Neighborhood Hits	220
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

ELTD1_MOUSE
NC score	0.571201 (rank : 152)	θ value	1.38499e-08 (rank : 167)
Query Neighborhood Hits	453	Target Neighborhood Hits	288	Shared Neighborhood Hits	206
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

LRP2_HUMAN
NC score	0.570805 (rank : 153)	θ value	5.44631e-05 (rank : 228)
Query Neighborhood Hits	453	Target Neighborhood Hits	573	Shared Neighborhood Hits	370
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LAMB1_MOUSE
NC score	0.570683 (rank : 154)	θ value	1.16975e-15 (rank : 111)
Query Neighborhood Hits	453	Target Neighborhood Hits	919	Shared Neighborhood Hits	274
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MATN3_MOUSE
NC score	0.570233 (rank : 155)	θ value	6.43352e-06 (rank : 213)
Query Neighborhood Hits	453	Target Neighborhood Hits	261	Shared Neighborhood Hits	205
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

LAMC2_HUMAN
NC score	0.567645 (rank : 156)	θ value	2.36244e-08 (rank : 171)
Query Neighborhood Hits	453	Target Neighborhood Hits	715	Shared Neighborhood Hits	266
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

MATN3_HUMAN
NC score	0.567254 (rank : 157)	θ value	4.92598e-06 (rank : 211)
Query Neighborhood Hits	453	Target Neighborhood Hits	268	Shared Neighborhood Hits	201
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

KR104_HUMAN
NC score	0.566150 (rank : 158)	θ value	0.0431538 (rank : 288)
Query Neighborhood Hits	453	Target Neighborhood Hits	313	Shared Neighborhood Hits	207
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR106_HUMAN
NC score	0.564961 (rank : 159)	θ value	4.1701e-05 (rank : 223)
Query Neighborhood Hits	453	Target Neighborhood Hits	347	Shared Neighborhood Hits	218
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

VLDLR_HUMAN
NC score	0.564769 (rank : 160)	θ value	7.84624e-12 (rank : 139)
Query Neighborhood Hits	453	Target Neighborhood Hits	383	Shared Neighborhood Hits	269
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
NC score	0.563815 (rank : 161)	θ value	4.59992e-12 (rank : 137)
Query Neighborhood Hits	453	Target Neighborhood Hits	360	Shared Neighborhood Hits	262
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

HHIP_MOUSE
NC score	0.560602 (rank : 162)	θ value	0.00390308 (rank : 258)
Query Neighborhood Hits	453	Target Neighborhood Hits	219	Shared Neighborhood Hits	187
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

NTNG2_MOUSE
NC score	0.557237 (rank : 163)	θ value	0.0148317 (rank : 279)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	240
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LAMC1_MOUSE
NC score	0.556723 (rank : 164)	θ value	2.36244e-08 (rank : 170)
Query Neighborhood Hits	453	Target Neighborhood Hits	856	Shared Neighborhood Hits	276
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMB3_MOUSE
NC score	0.552298 (rank : 165)	θ value	5.62301e-10 (rank : 148)
Query Neighborhood Hits	453	Target Neighborhood Hits	444	Shared Neighborhood Hits	228
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LRP8_MOUSE
NC score	0.551360 (rank : 166)	θ value	5.44631e-05 (rank : 229)
Query Neighborhood Hits	453	Target Neighborhood Hits	385	Shared Neighborhood Hits	273
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LAMB1_HUMAN
NC score	0.550538 (rank : 167)	θ value	3.40345e-15 (rank : 116)
Query Neighborhood Hits	453	Target Neighborhood Hits	1018	Shared Neighborhood Hits	288
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMA2_MOUSE
NC score	0.548354 (rank : 168)	θ value	1.68911e-14 (rank : 122)
Query Neighborhood Hits	453	Target Neighborhood Hits	1198	Shared Neighborhood Hits	310
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

NTNG2_HUMAN
NC score	0.546775 (rank : 169)	θ value	0.00390308 (rank : 261)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	243
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LAMC1_HUMAN
NC score	0.541042 (rank : 170)	θ value	2.79066e-09 (rank : 158)
Query Neighborhood Hits	453	Target Neighborhood Hits	922	Shared Neighborhood Hits	280
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

ITB6_MOUSE
NC score	0.540980 (rank : 171)	θ value	2.79066e-09 (rank : 157)
Query Neighborhood Hits	453	Target Neighborhood Hits	341	Shared Neighborhood Hits	256
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

LDLR_MOUSE
NC score	0.540232 (rank : 172)	θ value	1.25267e-09 (rank : 151)
Query Neighborhood Hits	453	Target Neighborhood Hits	382	Shared Neighborhood Hits	268
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LAMA3_MOUSE
NC score	0.537932 (rank : 173)	θ value	1.99992e-07 (rank : 182)
Query Neighborhood Hits	453	Target Neighborhood Hits	859	Shared Neighborhood Hits	299
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

MFGM_MOUSE
NC score	0.535728 (rank : 174)	θ value	7.59969e-07 (rank : 192)
Query Neighborhood Hits	453	Target Neighborhood Hits	233	Shared Neighborhood Hits	205
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

LRP8_HUMAN
NC score	0.534101 (rank : 175)	θ value	2.88788e-06 (rank : 204)
Query Neighborhood Hits	453	Target Neighborhood Hits	346	Shared Neighborhood Hits	247
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

MATN4_MOUSE
NC score	0.529937 (rank : 176)	θ value	0.0736092 (rank : 296)
Query Neighborhood Hits	453	Target Neighborhood Hits	277	Shared Neighborhood Hits	213
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

KRA59_HUMAN
NC score	0.525271 (rank : 177)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	453	Target Neighborhood Hits	310	Shared Neighborhood Hits	190
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

NTNG1_MOUSE
NC score	0.523146 (rank : 178)	θ value	1.09739e-05 (rank : 214)
Query Neighborhood Hits	453	Target Neighborhood Hits	246	Shared Neighborhood Hits	211
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

KRA57_HUMAN
NC score	0.520800 (rank : 179)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	453	Target Neighborhood Hits	269	Shared Neighborhood Hits	188
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA55_HUMAN
NC score	0.520285 (rank : 180)	θ value	0.62314 (rank : 342)
Query Neighborhood Hits	453	Target Neighborhood Hits	257	Shared Neighborhood Hits	183
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

NTNG1_HUMAN
NC score	0.520082 (rank : 181)	θ value	0.00035302 (rank : 242)
Query Neighborhood Hits	453	Target Neighborhood Hits	247	Shared Neighborhood Hits	208
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

LAMB3_HUMAN
NC score	0.520059 (rank : 182)	θ value	8.11959e-09 (rank : 162)
Query Neighborhood Hits	453	Target Neighborhood Hits	461	Shared Neighborhood Hits	204
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

ITB6_HUMAN
NC score	0.519277 (rank : 183)	θ value	1.133e-10 (rank : 145)
Query Neighborhood Hits	453	Target Neighborhood Hits	318	Shared Neighborhood Hits	240
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

USH2A_MOUSE
NC score	0.515176 (rank : 184)	θ value	8.11959e-09 (rank : 164)
Query Neighborhood Hits	453	Target Neighborhood Hits	626	Shared Neighborhood Hits	268
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

ITB5_MOUSE
NC score	0.512974 (rank : 185)	θ value	9.92553e-07 (rank : 194)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	251
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

FATH_HUMAN
NC score	0.511277 (rank : 186)	θ value	4.00176e-32 (rank : 50)
Query Neighborhood Hits	453	Target Neighborhood Hits	570	Shared Neighborhood Hits	335
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

TSP1_MOUSE
NC score	0.502615 (rank : 187)	θ value	1.63604e-09 (rank : 155)
Query Neighborhood Hits	453	Target Neighborhood Hits	396	Shared Neighborhood Hits	239
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

ITB5_HUMAN
NC score	0.499372 (rank : 188)	θ value	3.41135e-07 (rank : 185)
Query Neighborhood Hits	453	Target Neighborhood Hits	310	Shared Neighborhood Hits	238
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB7_MOUSE
NC score	0.498710 (rank : 189)	θ value	3.64472e-09 (rank : 160)
Query Neighborhood Hits	453	Target Neighborhood Hits	277	Shared Neighborhood Hits	225
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

USH2A_HUMAN
NC score	0.498163 (rank : 190)	θ value	1.63604e-09 (rank : 156)
Query Neighborhood Hits	453	Target Neighborhood Hits	600	Shared Neighborhood Hits	252
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

TSP1_HUMAN
NC score	0.497784 (rank : 191)	θ value	1.06045e-08 (rank : 166)
Query Neighborhood Hits	453	Target Neighborhood Hits	389	Shared Neighborhood Hits	235
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

ITB7_HUMAN
NC score	0.496857 (rank : 192)	θ value	3.41135e-07 (rank : 186)
Query Neighborhood Hits	453	Target Neighborhood Hits	290	Shared Neighborhood Hits	233
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

PGBM_MOUSE
NC score	0.496664 (rank : 193)	θ value	1.058e-16 (rank : 101)
Query Neighborhood Hits	453	Target Neighborhood Hits	1073	Shared Neighborhood Hits	346
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

GRN_MOUSE
NC score	0.496325 (rank : 194)	θ value	4.1701e-05 (rank : 222)
Query Neighborhood Hits	453	Target Neighborhood Hits	248	Shared Neighborhood Hits	174
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

KRA54_HUMAN
NC score	0.496045 (rank : 195)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	453	Target Neighborhood Hits	270	Shared Neighborhood Hits	178
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

LRP4_MOUSE
NC score	0.494832 (rank : 196)	θ value	0.00869519 (rank : 272)
Query Neighborhood Hits	453	Target Neighborhood Hits	351	Shared Neighborhood Hits	256
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

KR101_HUMAN
NC score	0.493154 (rank : 197)	θ value	0.00228821 (rank : 253)
Query Neighborhood Hits	453	Target Neighborhood Hits	261	Shared Neighborhood Hits	171
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

PGBM_HUMAN
NC score	0.492529 (rank : 198)	θ value	1.86321e-21 (rank : 72)
Query Neighborhood Hits	453	Target Neighborhood Hits	1113	Shared Neighborhood Hits	355
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

LAMA4_MOUSE
NC score	0.492077 (rank : 199)	θ value	3.41135e-07 (rank : 187)
Query Neighborhood Hits	453	Target Neighborhood Hits	584	Shared Neighborhood Hits	219
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LRP4_HUMAN
NC score	0.491789 (rank : 200)	θ value	0.000270298 (rank : 241)
Query Neighborhood Hits	453	Target Neighborhood Hits	355	Shared Neighborhood Hits	258
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

GRN_HUMAN
NC score	0.490491 (rank : 201)	θ value	0.00175202 (rank : 251)
Query Neighborhood Hits	453	Target Neighborhood Hits	268	Shared Neighborhood Hits	178
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

ITB3_HUMAN
NC score	0.488747 (rank : 202)	θ value	0.00390308 (rank : 259)
Query Neighborhood Hits	453	Target Neighborhood Hits	325	Shared Neighborhood Hits	250
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB2_MOUSE
NC score	0.483770 (rank : 203)	θ value	3.77169e-06 (rank : 205)
Query Neighborhood Hits	453	Target Neighborhood Hits	326	Shared Neighborhood Hits	250
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

KR171_HUMAN
NC score	0.480488 (rank : 204)	θ value	0.163984 (rank : 308)
Query Neighborhood Hits	453	Target Neighborhood Hits	144	Shared Neighborhood Hits	112
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

HMCN1_HUMAN
NC score	0.480282 (rank : 205)	θ value	1.5242e-23 (rank : 65)
Query Neighborhood Hits	453	Target Neighborhood Hits	983	Shared Neighborhood Hits	290
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

CELR2_HUMAN
NC score	0.477889 (rank : 206)	θ value	3.61106e-41 (rank : 35)
Query Neighborhood Hits	453	Target Neighborhood Hits	657	Shared Neighborhood Hits	346
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

LAMA3_HUMAN
NC score	0.477537 (rank : 207)	θ value	5.44631e-05 (rank : 227)
Query Neighborhood Hits	453	Target Neighborhood Hits	760	Shared Neighborhood Hits	250
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

CELR3_HUMAN
NC score	0.476077 (rank : 208)	θ value	2.58786e-39 (rank : 36)
Query Neighborhood Hits	453	Target Neighborhood Hits	680	Shared Neighborhood Hits	324
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
NC score	0.469444 (rank : 209)	θ value	1.20211e-36 (rank : 40)
Query Neighborhood Hits	453	Target Neighborhood Hits	687	Shared Neighborhood Hits	326
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

ITB1_MOUSE
NC score	0.469188 (rank : 210)	θ value	0.00102713 (rank : 246)
Query Neighborhood Hits	453	Target Neighborhood Hits	283	Shared Neighborhood Hits	212
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_HUMAN
NC score	0.468759 (rank : 211)	θ value	9.29e-05 (rank : 233)
Query Neighborhood Hits	453	Target Neighborhood Hits	282	Shared Neighborhood Hits	219
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

LAMA4_HUMAN
NC score	0.467742 (rank : 212)	θ value	7.59969e-07 (rank : 191)
Query Neighborhood Hits	453	Target Neighborhood Hits	708	Shared Neighborhood Hits	219
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

ITB3_MOUSE
NC score	0.466893 (rank : 213)	θ value	0.62314 (rank : 340)
Query Neighborhood Hits	453	Target Neighborhood Hits	319	Shared Neighborhood Hits	238
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB4_HUMAN
NC score	0.462396 (rank : 214)	θ value	2.44474e-05 (rank : 220)
Query Neighborhood Hits	453	Target Neighborhood Hits	458	Shared Neighborhood Hits	242
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ITB1_HUMAN
NC score	0.460284 (rank : 215)	θ value	1.43324e-05 (rank : 217)
Query Neighborhood Hits	453	Target Neighborhood Hits	298	Shared Neighborhood Hits	218
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

CELR1_MOUSE
NC score	0.459925 (rank : 216)	θ value	3.06405e-32 (rank : 49)
Query Neighborhood Hits	453	Target Neighborhood Hits	617	Shared Neighborhood Hits	308
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR1_HUMAN
NC score	0.459429 (rank : 217)	θ value	4.41421e-39 (rank : 37)
Query Neighborhood Hits	453	Target Neighborhood Hits	613	Shared Neighborhood Hits	310
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

KR102_HUMAN
NC score	0.458651 (rank : 218)	θ value	0.00298849 (rank : 255)
Query Neighborhood Hits	453	Target Neighborhood Hits	264	Shared Neighborhood Hits	169
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

TSP2_HUMAN
NC score	0.457663 (rank : 219)	θ value	2.61198e-07 (rank : 184)
Query Neighborhood Hits	453	Target Neighborhood Hits	359	Shared Neighborhood Hits	215
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

CFC1_HUMAN
NC score	0.457381 (rank : 220)	θ value	0.47712 (rank : 332)
Query Neighborhood Hits	453	Target Neighborhood Hits	148	Shared Neighborhood Hits	144
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

TENR_MOUSE
NC score	0.455223 (rank : 221)	θ value	2.21117e-06 (rank : 203)
Query Neighborhood Hits	453	Target Neighborhood Hits	531	Shared Neighborhood Hits	270
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

KR511_HUMAN
NC score	0.450644 (rank : 222)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	453	Target Neighborhood Hits	231	Shared Neighborhood Hits	157
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

ATRN_MOUSE
NC score	0.448917 (rank : 223)	θ value	0.00509761 (rank : 262)
Query Neighborhood Hits	453	Target Neighborhood Hits	519	Shared Neighborhood Hits	269
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

TSP2_MOUSE
NC score	0.448505 (rank : 224)	θ value	5.81887e-07 (rank : 189)
Query Neighborhood Hits	453	Target Neighborhood Hits	352	Shared Neighborhood Hits	217
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ATRN_HUMAN
NC score	0.448216 (rank : 225)	θ value	0.00665767 (rank : 266)
Query Neighborhood Hits	453	Target Neighborhood Hits	525	Shared Neighborhood Hits	272
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

TENR_HUMAN
NC score	0.447303 (rank : 226)	θ value	1.09739e-05 (rank : 215)
Query Neighborhood Hits	453	Target Neighborhood Hits	526	Shared Neighborhood Hits	267
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

KR105_HUMAN
NC score	0.441463 (rank : 227)	θ value	0.00298849 (rank : 256)
Query Neighborhood Hits	453	Target Neighborhood Hits	271	Shared Neighborhood Hits	175
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

CELR2_MOUSE
NC score	0.441304 (rank : 228)	θ value	5.0505e-35 (rank : 44)
Query Neighborhood Hits	453	Target Neighborhood Hits	584	Shared Neighborhood Hits	305
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

ELTD1_HUMAN
NC score	0.439103 (rank : 229)	θ value	0.00102713 (rank : 245)
Query Neighborhood Hits	453	Target Neighborhood Hits	269	Shared Neighborhood Hits	182
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

TDGF1_MOUSE
NC score	0.432963 (rank : 230)	θ value	0.00134147 (rank : 250)
Query Neighborhood Hits	453	Target Neighborhood Hits	146	Shared Neighborhood Hits	143
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

CFC1_MOUSE
NC score	0.430419 (rank : 231)	θ value	0.62314 (rank : 339)
Query Neighborhood Hits	453	Target Neighborhood Hits	125	Shared Neighborhood Hits	124
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

PCSK5_MOUSE
NC score	0.428799 (rank : 232)	θ value	0.0252991 (rank : 285)
Query Neighborhood Hits	453	Target Neighborhood Hits	613	Shared Neighborhood Hits	289
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

KRA52_HUMAN
NC score	0.428484 (rank : 233)	θ value	8.99809 (rank : 449)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	164
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

CRIM1_HUMAN
NC score	0.426381 (rank : 234)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	453	Target Neighborhood Hits	362	Shared Neighborhood Hits	193
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KRA56_HUMAN
NC score	0.423283 (rank : 235)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	453	Target Neighborhood Hits	207	Shared Neighborhood Hits	157
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KR109_HUMAN
NC score	0.416846 (rank : 236)	θ value	0.0961366 (rank : 300)
Query Neighborhood Hits	453	Target Neighborhood Hits	226	Shared Neighborhood Hits	152
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR108_HUMAN
NC score	0.412228 (rank : 237)	θ value	0.0330416 (rank : 286)
Query Neighborhood Hits	453	Target Neighborhood Hits	226	Shared Neighborhood Hits	149
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

HABP2_MOUSE
NC score	0.410068 (rank : 238)	θ value	1.38178e-16 (rank : 102)
Query Neighborhood Hits	453	Target Neighborhood Hits	445	Shared Neighborhood Hits	271
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

KR10C_HUMAN
NC score	0.409841 (rank : 239)	θ value	0.00509761 (rank : 264)
Query Neighborhood Hits	453	Target Neighborhood Hits	219	Shared Neighborhood Hits	154
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

HABP2_HUMAN
NC score	0.409663 (rank : 240)	θ value	5.8054e-15 (rank : 119)
Query Neighborhood Hits	453	Target Neighborhood Hits	431	Shared Neighborhood Hits	262
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LYAM3_MOUSE
NC score	0.408350 (rank : 241)	θ value	0.00020696 (rank : 237)
Query Neighborhood Hits	453	Target Neighborhood Hits	390	Shared Neighborhood Hits	249
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

SSPO_MOUSE
NC score	0.400277 (rank : 242)	θ value	0.000121331 (rank : 234)
Query Neighborhood Hits	453	Target Neighborhood Hits	800	Shared Neighborhood Hits	314
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ITB8_HUMAN
NC score	0.400226 (rank : 243)	θ value	0.00020696 (rank : 235)
Query Neighborhood Hits	453	Target Neighborhood Hits	280	Shared Neighborhood Hits	220
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

NRX1A_HUMAN
NC score	0.392742 (rank : 244)	θ value	3.77169e-06 (rank : 206)
Query Neighborhood Hits	453	Target Neighborhood Hits	170	Shared Neighborhood Hits	140
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
NC score	0.391662 (rank : 245)	θ value	3.77169e-06 (rank : 207)
Query Neighborhood Hits	453	Target Neighborhood Hits	164	Shared Neighborhood Hits	139
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NET2_MOUSE
NC score	0.391474 (rank : 246)	θ value	0.0252991 (rank : 284)
Query Neighborhood Hits	453	Target Neighborhood Hits	193	Shared Neighborhood Hits	154
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

LYAM2_MOUSE
NC score	0.390904 (rank : 247)	θ value	4.1701e-05 (rank : 224)
Query Neighborhood Hits	453	Target Neighborhood Hits	420	Shared Neighborhood Hits	261
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

KR510_HUMAN
NC score	0.389489 (rank : 248)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	453	Target Neighborhood Hits	217	Shared Neighborhood Hits	147
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

NET4_HUMAN
NC score	0.389338 (rank : 249)	θ value	0.62314 (rank : 345)
Query Neighborhood Hits	453	Target Neighborhood Hits	191	Shared Neighborhood Hits	156
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

LYAM2_HUMAN
NC score	0.387994 (rank : 250)	θ value	0.00228821 (rank : 254)
Query Neighborhood Hits	453	Target Neighborhood Hits	394	Shared Neighborhood Hits	250
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

TENN_MOUSE
NC score	0.387068 (rank : 251)	θ value	9.92553e-07 (rank : 196)
Query Neighborhood Hits	453	Target Neighborhood Hits	484	Shared Neighborhood Hits	248
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

NET2_HUMAN
NC score	0.386207 (rank : 252)	θ value	0.0431538 (rank : 289)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	151
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET4_MOUSE
NC score	0.383266 (rank : 253)	θ value	1.06291 (rank : 363)
Query Neighborhood Hits	453	Target Neighborhood Hits	180	Shared Neighborhood Hits	152
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

FRAS1_HUMAN
NC score	0.378997 (rank : 254)	θ value	6.88961 (rank : 430)
Query Neighborhood Hits	453	Target Neighborhood Hits	759	Shared Neighborhood Hits	266
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

NRX3A_HUMAN
NC score	0.377188 (rank : 255)	θ value	9.92553e-07 (rank : 195)
Query Neighborhood Hits	453	Target Neighborhood Hits	164	Shared Neighborhood Hits	145
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

KR10B_HUMAN
NC score	0.376585 (rank : 256)	θ value	0.279714 (rank : 318)
Query Neighborhood Hits	453	Target Neighborhood Hits	269	Shared Neighborhood Hits	170
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

ZAN_HUMAN
NC score	0.373762 (rank : 257)	θ value	1.09739e-05 (rank : 216)
Query Neighborhood Hits	453	Target Neighborhood Hits	679	Shared Neighborhood Hits	268
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

TDGF1_HUMAN
NC score	0.371077 (rank : 258)	θ value	0.0736092 (rank : 298)
Query Neighborhood Hits	453	Target Neighborhood Hits	132	Shared Neighborhood Hits	128
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

CNTP2_MOUSE
NC score	0.368433 (rank : 259)	θ value	1.69304e-06 (rank : 200)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	145
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

TENN_HUMAN
NC score	0.367212 (rank : 260)	θ value	4.92598e-06 (rank : 212)
Query Neighborhood Hits	453	Target Neighborhood Hits	453	Shared Neighborhood Hits	243
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

CNTP2_HUMAN
NC score	0.364392 (rank : 261)	θ value	4.92598e-06 (rank : 209)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

SORL_MOUSE
NC score	0.363664 (rank : 262)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	453	Target Neighborhood Hits	439	Shared Neighborhood Hits	223
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TDGF2_HUMAN
NC score	0.362460 (rank : 263)	θ value	0.21417 (rank : 315)
Query Neighborhood Hits	453	Target Neighborhood Hits	131	Shared Neighborhood Hits	125
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

LYAM3_HUMAN
NC score	0.361395 (rank : 264)	θ value	0.00665767 (rank : 268)
Query Neighborhood Hits	453	Target Neighborhood Hits	378	Shared Neighborhood Hits	228
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

FRAS1_MOUSE
NC score	0.358816 (rank : 265)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	453	Target Neighborhood Hits	747	Shared Neighborhood Hits	259
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

CNTP4_MOUSE
NC score	0.358712 (rank : 266)	θ value	2.36244e-08 (rank : 169)
Query Neighborhood Hits	453	Target Neighborhood Hits	193	Shared Neighborhood Hits	148
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

NRX2A_HUMAN
NC score	0.356292 (rank : 267)	θ value	6.87365e-08 (rank : 176)
Query Neighborhood Hits	453	Target Neighborhood Hits	614	Shared Neighborhood Hits	147
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

CNTP4_HUMAN
NC score	0.352672 (rank : 268)	θ value	1.25267e-09 (rank : 149)
Query Neighborhood Hits	453	Target Neighborhood Hits	187	Shared Neighborhood Hits	128
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

FA10_MOUSE
NC score	0.351675 (rank : 269)	θ value	1.53129e-07 (rank : 181)
Query Neighborhood Hits	453	Target Neighborhood Hits	435	Shared Neighborhood Hits	264
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

SORL_HUMAN
NC score	0.351107 (rank : 270)	θ value	0.365318 (rank : 328)
Query Neighborhood Hits	453	Target Neighborhood Hits	440	Shared Neighborhood Hits	215
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

PGCB_MOUSE
NC score	0.349796 (rank : 271)	θ value	8.97725e-08 (rank : 178)
Query Neighborhood Hits	453	Target Neighborhood Hits	459	Shared Neighborhood Hits	191
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

EMR3_HUMAN
NC score	0.347126 (rank : 272)	θ value	1.81305 (rank : 382)
Query Neighborhood Hits	453	Target Neighborhood Hits	245	Shared Neighborhood Hits	157
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

CNTP3_HUMAN
NC score	0.347106 (rank : 273)	θ value	1.133e-10 (rank : 144)
Query Neighborhood Hits	453	Target Neighborhood Hits	195	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

KRA93_HUMAN
NC score	0.347009 (rank : 274)	θ value	0.21417 (rank : 314)
Query Neighborhood Hits	453	Target Neighborhood Hits	203	Shared Neighborhood Hits	127
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
NC score	0.345878 (rank : 275)	θ value	6.88961 (rank : 434)
Query Neighborhood Hits	453	Target Neighborhood Hits	204	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

FAT2_HUMAN
NC score	0.345313 (rank : 276)	θ value	9.90251e-15 (rank : 120)
Query Neighborhood Hits	453	Target Neighborhood Hits	507	Shared Neighborhood Hits	239
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

NET1_HUMAN
NC score	0.344252 (rank : 277)	θ value	0.0148317 (rank : 277)
Query Neighborhood Hits	453	Target Neighborhood Hits	149	Shared Neighborhood Hits	118
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

FA10_HUMAN
NC score	0.343554 (rank : 278)	θ value	1.69304e-06 (rank : 202)
Query Neighborhood Hits	453	Target Neighborhood Hits	431	Shared Neighborhood Hits	252
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

KRA98_HUMAN
NC score	0.341312 (rank : 279)	θ value	2.36792 (rank : 392)
Query Neighborhood Hits	453	Target Neighborhood Hits	185	Shared Neighborhood Hits	120
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

NET1_MOUSE
NC score	0.338296 (rank : 280)	θ value	0.0148317 (rank : 278)
Query Neighborhood Hits	453	Target Neighborhood Hits	151	Shared Neighborhood Hits	116
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

FA9_HUMAN
NC score	0.336543 (rank : 281)	θ value	8.97725e-08 (rank : 177)
Query Neighborhood Hits	453	Target Neighborhood Hits	421	Shared Neighborhood Hits	251
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

KRA13_HUMAN
NC score	0.334303 (rank : 282)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	453	Target Neighborhood Hits	144	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

PROC_MOUSE
NC score	0.328109 (rank : 283)	θ value	1.99992e-07 (rank : 183)
Query Neighborhood Hits	453	Target Neighborhood Hits	426	Shared Neighborhood Hits	257
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

CNTP1_HUMAN
NC score	0.327821 (rank : 284)	θ value	1.80886e-08 (rank : 168)
Query Neighborhood Hits	453	Target Neighborhood Hits	196	Shared Neighborhood Hits	124
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

KRA44_HUMAN
NC score	0.325771 (rank : 285)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	453	Target Neighborhood Hits	162	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

PGCB_HUMAN
NC score	0.325467 (rank : 286)	θ value	1.29631e-06 (rank : 199)
Query Neighborhood Hits	453	Target Neighborhood Hits	478	Shared Neighborhood Hits	184
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

LYAM1_MOUSE
NC score	0.324635 (rank : 287)	θ value	0.00869519 (rank : 273)
Query Neighborhood Hits	453	Target Neighborhood Hits	332	Shared Neighborhood Hits	197
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

KRA45_HUMAN
NC score	0.323643 (rank : 288)	θ value	1.06291 (rank : 360)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	126
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

LYAM1_HUMAN
NC score	0.321182 (rank : 289)	θ value	0.0193708 (rank : 282)
Query Neighborhood Hits	453	Target Neighborhood Hits	315	Shared Neighborhood Hits	194
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

KR10A_HUMAN
NC score	0.320540 (rank : 290)	θ value	5.44631e-05 (rank : 226)
Query Neighborhood Hits	453	Target Neighborhood Hits	232	Shared Neighborhood Hits	146
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

CNTP1_MOUSE
NC score	0.320396 (rank : 291)	θ value	3.08544e-08 (rank : 172)
Query Neighborhood Hits	453	Target Neighborhood Hits	183	Shared Neighborhood Hits	118
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

FA7_HUMAN
NC score	0.319367 (rank : 292)	θ value	9.92553e-07 (rank : 193)
Query Neighborhood Hits	453	Target Neighborhood Hits	404	Shared Neighborhood Hits	238
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

HGFA_HUMAN
NC score	0.318859 (rank : 293)	θ value	2.0648e-12 (rank : 133)
Query Neighborhood Hits	453	Target Neighborhood Hits	436	Shared Neighborhood Hits	234
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

TEFF2_MOUSE
NC score	0.315984 (rank : 294)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	453	Target Neighborhood Hits	214	Shared Neighborhood Hits	141
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

KR414_HUMAN
NC score	0.315713 (rank : 295)	θ value	8.99809 (rank : 448)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	129
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

PERT_HUMAN
NC score	0.315612 (rank : 296)	θ value	0.00509761 (rank : 265)
Query Neighborhood Hits	453	Target Neighborhood Hits	221	Shared Neighborhood Hits	165
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

KRA92_HUMAN
NC score	0.314670 (rank : 297)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	453	Target Neighborhood Hits	198	Shared Neighborhood Hits	126
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

HGFA_MOUSE
NC score	0.313381 (rank : 298)	θ value	2.0648e-12 (rank : 134)
Query Neighborhood Hits	453	Target Neighborhood Hits	419	Shared Neighborhood Hits	237
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

TEFF2_HUMAN
NC score	0.313209 (rank : 299)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	453	Target Neighborhood Hits	211	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

KRA11_HUMAN
NC score	0.313109 (rank : 300)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	453	Target Neighborhood Hits	155	Shared Neighborhood Hits	114
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA47_HUMAN
NC score	0.306955 (rank : 301)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	453	Target Neighborhood Hits	204	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KR103_HUMAN
NC score	0.304851 (rank : 302)	θ value	6.88961 (rank : 433)
Query Neighborhood Hits	453	Target Neighborhood Hits	212	Shared Neighborhood Hits	131
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

MFGM_HUMAN
NC score	0.304423 (rank : 303)	θ value	0.00665767 (rank : 269)
Query Neighborhood Hits	453	Target Neighborhood Hits	150	Shared Neighborhood Hits	128
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

LCE1B_HUMAN
NC score	0.304304 (rank : 304)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	453	Target Neighborhood Hits	58	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

MUC13_MOUSE
NC score	0.301417 (rank : 305)	θ value	8.99809 (rank : 451)
Query Neighborhood Hits	453	Target Neighborhood Hits	447	Shared Neighborhood Hits	164
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

NFX1_HUMAN
NC score	0.299570 (rank : 306)	θ value	6.88961 (rank : 437)
Query Neighborhood Hits	453	Target Neighborhood Hits	405	Shared Neighborhood Hits	152
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

PROC_HUMAN
NC score	0.296796 (rank : 307)	θ value	5.26297e-08 (rank : 174)
Query Neighborhood Hits	453	Target Neighborhood Hits	406	Shared Neighborhood Hits	245
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

MUC5B_HUMAN
NC score	0.294453 (rank : 308)	θ value	0.00390308 (rank : 260)
Query Neighborhood Hits	453	Target Neighborhood Hits	1020	Shared Neighborhood Hits	251
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

KRA99_HUMAN
NC score	0.294261 (rank : 309)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	453	Target Neighborhood Hits	173	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LCE1C_HUMAN
NC score	0.293605 (rank : 310)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	453	Target Neighborhood Hits	65	Shared Neighborhood Hits	41
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

UROL1_MOUSE
NC score	0.290520 (rank : 311)	θ value	0.62314 (rank : 349)
Query Neighborhood Hits	453	Target Neighborhood Hits	235	Shared Neighborhood Hits	140
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

FA12_HUMAN
NC score	0.289440 (rank : 312)	θ value	5.26297e-08 (rank : 173)
Query Neighborhood Hits	453	Target Neighborhood Hits	425	Shared Neighborhood Hits	228
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

CRAC1_MOUSE
NC score	0.289070 (rank : 313)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	453	Target Neighborhood Hits	112	Shared Neighborhood Hits	96
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_HUMAN
NC score	0.287694 (rank : 314)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	453	Target Neighborhood Hits	111	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

PERT_MOUSE
NC score	0.287096 (rank : 315)	θ value	1.38821 (rank : 375)
Query Neighborhood Hits	453	Target Neighborhood Hits	221	Shared Neighborhood Hits	157
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

VWF_HUMAN
NC score	0.285832 (rank : 316)	θ value	1.38821 (rank : 376)
Query Neighborhood Hits	453	Target Neighborhood Hits	396	Shared Neighborhood Hits	203
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

MMRN1_HUMAN
NC score	0.284104 (rank : 317)	θ value	0.00298849 (rank : 257)
Query Neighborhood Hits	453	Target Neighborhood Hits	636	Shared Neighborhood Hits	159
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

FA7_MOUSE
NC score	0.281000 (rank : 318)	θ value	1.29631e-06 (rank : 198)
Query Neighborhood Hits	453	Target Neighborhood Hits	374	Shared Neighborhood Hits	213
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

KRA15_HUMAN
NC score	0.280166 (rank : 319)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	453	Target Neighborhood Hits	126	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KR412_HUMAN
NC score	0.276596 (rank : 320)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	453	Target Neighborhood Hits	178	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

LCE1D_HUMAN
NC score	0.269724 (rank : 321)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	453	Target Neighborhood Hits	44	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

CLC14_MOUSE
NC score	0.269383 (rank : 322)	θ value	6.88961 (rank : 427)
Query Neighborhood Hits	453	Target Neighborhood Hits	120	Shared Neighborhood Hits	108
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

UROL1_HUMAN
NC score	0.267426 (rank : 323)	θ value	3.0926 (rank : 402)
Query Neighborhood Hits	453	Target Neighborhood Hits	213	Shared Neighborhood Hits	133
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

PGH2_MOUSE
NC score	0.263395 (rank : 324)	θ value	0.62314 (rank : 347)
Query Neighborhood Hits	453	Target Neighborhood Hits	113	Shared Neighborhood Hits	104
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

CLC14_HUMAN
NC score	0.263022 (rank : 325)	θ value	0.47712 (rank : 333)
Query Neighborhood Hits	453	Target Neighborhood Hits	143	Shared Neighborhood Hits	112
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

VWF_MOUSE
NC score	0.257153 (rank : 326)	θ value	0.00102713 (rank : 248)
Query Neighborhood Hits	453	Target Neighborhood Hits	381	Shared Neighborhood Hits	182
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

EMR4_MOUSE
NC score	0.256468 (rank : 327)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	453	Target Neighborhood Hits	191	Shared Neighborhood Hits	116
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

BMP1_MOUSE
NC score	0.253659 (rank : 328)	θ value	1.38821 (rank : 369)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	169
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL1_MOUSE
NC score	0.253601 (rank : 329)	θ value	1.06291 (rank : 366)
Query Neighborhood Hits	453	Target Neighborhood Hits	237	Shared Neighborhood Hits	167
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

RELN_MOUSE
NC score	0.252234 (rank : 330)	θ value	0.47712 (rank : 336)
Query Neighborhood Hits	453	Target Neighborhood Hits	235	Shared Neighborhood Hits	179
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

BMP1_HUMAN
NC score	0.251697 (rank : 331)	θ value	1.38821 (rank : 368)
Query Neighborhood Hits	453	Target Neighborhood Hits	233	Shared Neighborhood Hits	168
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

PGCA_HUMAN
NC score	0.250858 (rank : 332)	θ value	0.00020696 (rank : 240)
Query Neighborhood Hits	453	Target Neighborhood Hits	821	Shared Neighborhood Hits	177
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

LRP6_HUMAN
NC score	0.250615 (rank : 333)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	453	Target Neighborhood Hits	235	Shared Neighborhood Hits	158
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LCE1E_HUMAN
NC score	0.249047 (rank : 334)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	453	Target Neighborhood Hits	53	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

TLL2_HUMAN
NC score	0.247438 (rank : 335)	θ value	0.279714 (rank : 323)
Query Neighborhood Hits	453	Target Neighborhood Hits	241	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

LRP6_MOUSE
NC score	0.246439 (rank : 336)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	453	Target Neighborhood Hits	232	Shared Neighborhood Hits	155
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

TLL1_HUMAN
NC score	0.246081 (rank : 337)	θ value	1.06291 (rank : 365)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	164
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

SMDF_HUMAN
NC score	0.242332 (rank : 338)	θ value	1.81305 (rank : 386)
Query Neighborhood Hits	453	Target Neighborhood Hits	117	Shared Neighborhood Hits	82
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

PGH2_HUMAN
NC score	0.240580 (rank : 339)	θ value	0.279714 (rank : 321)
Query Neighborhood Hits	453	Target Neighborhood Hits	103	Shared Neighborhood Hits	93
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

RELN_HUMAN
NC score	0.240451 (rank : 340)	θ value	0.813845 (rank : 357)
Query Neighborhood Hits	453	Target Neighborhood Hits	233	Shared Neighborhood Hits	176
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

TLL2_MOUSE
NC score	0.238767 (rank : 341)	θ value	0.62314 (rank : 348)
Query Neighborhood Hits	453	Target Neighborhood Hits	240	Shared Neighborhood Hits	166
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

MEP1A_MOUSE
NC score	0.238076 (rank : 342)	θ value	0.279714 (rank : 319)
Query Neighborhood Hits	453	Target Neighborhood Hits	166	Shared Neighborhood Hits	134
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

LRP5_MOUSE
NC score	0.238067 (rank : 343)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	151
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

NRG2_MOUSE
NC score	0.236970 (rank : 344)	θ value	0.0563607 (rank : 292)
Query Neighborhood Hits	453	Target Neighborhood Hits	392	Shared Neighborhood Hits	123
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

TIE1_HUMAN
NC score	0.234936 (rank : 345)	θ value	1.133e-10 (rank : 146)
Query Neighborhood Hits	453	Target Neighborhood Hits	1241	Shared Neighborhood Hits	273
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

LRP5_HUMAN
NC score	0.232542 (rank : 346)	θ value	1.38821 (rank : 372)
Query Neighborhood Hits	453	Target Neighborhood Hits	224	Shared Neighborhood Hits	148
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

NRG1_HUMAN
NC score	0.231129 (rank : 347)	θ value	0.62314 (rank : 346)
Query Neighborhood Hits	453	Target Neighborhood Hits	285	Shared Neighborhood Hits	96
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRG4_HUMAN
NC score	0.231041 (rank : 348)	θ value	1.38821 (rank : 374)
Query Neighborhood Hits	453	Target Neighborhood Hits	85	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

PGH1_MOUSE
NC score	0.230851 (rank : 349)	θ value	0.365318 (rank : 327)
Query Neighborhood Hits	453	Target Neighborhood Hits	100	Shared Neighborhood Hits	84
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

TIE1_MOUSE
NC score	0.230760 (rank : 350)	θ value	1.47974e-10 (rank : 147)
Query Neighborhood Hits	453	Target Neighborhood Hits	1266	Shared Neighborhood Hits	270
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

LCE1F_HUMAN
NC score	0.229936 (rank : 351)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	453	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

MEP1A_HUMAN
NC score	0.228874 (rank : 352)	θ value	0.47712 (rank : 335)
Query Neighborhood Hits	453	Target Neighborhood Hits	162	Shared Neighborhood Hits	135
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

LCE1A_HUMAN
NC score	0.221699 (rank : 353)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	453	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

NRG4_MOUSE
NC score	0.219430 (rank : 354)	θ value	2.36792 (rank : 395)
Query Neighborhood Hits	453	Target Neighborhood Hits	79	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

PCSK5_HUMAN
NC score	0.215462 (rank : 355)	θ value	6.88961 (rank : 438)
Query Neighborhood Hits	453	Target Neighborhood Hits	291	Shared Neighborhood Hits	171
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

CO7_HUMAN
NC score	0.214722 (rank : 356)	θ value	0.0113563 (rank : 275)
Query Neighborhood Hits	453	Target Neighborhood Hits	278	Shared Neighborhood Hits	133
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

MUC13_HUMAN
NC score	0.213837 (rank : 357)	θ value	1.06291 (rank : 362)
Query Neighborhood Hits	453	Target Neighborhood Hits	164	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

CO6_HUMAN
NC score	0.208180 (rank : 358)	θ value	3.0926 (rank : 398)
Query Neighborhood Hits	453	Target Neighborhood Hits	331	Shared Neighborhood Hits	157
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

APR3_MOUSE
NC score	0.208033 (rank : 359)	θ value	0.279714 (rank : 316)
Query Neighborhood Hits	453	Target Neighborhood Hits	61	Shared Neighborhood Hits	57
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

TECTA_MOUSE
NC score	0.207036 (rank : 360)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	453	Target Neighborhood Hits	244	Shared Neighborhood Hits	175
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

KR410_HUMAN
NC score	0.206072 (rank : 361)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	453	Target Neighborhood Hits	156	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

RECK_HUMAN
NC score	0.205356 (rank : 362)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	453	Target Neighborhood Hits	189	Shared Neighborhood Hits	108
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

CORIN_HUMAN
NC score	0.203464 (rank : 363)	θ value	1.81305 (rank : 380)
Query Neighborhood Hits	453	Target Neighborhood Hits	453	Shared Neighborhood Hits	203
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

MATN1_HUMAN
NC score	0.203407 (rank : 364)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	453	Target Neighborhood Hits	191	Shared Neighborhood Hits	136
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

ESM1_HUMAN
NC score	0.202975 (rank : 365)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	453	Target Neighborhood Hits	110	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

MATN1_MOUSE
NC score	0.202601 (rank : 366)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	453	Target Neighborhood Hits	186	Shared Neighborhood Hits	131
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

TIE2_HUMAN
NC score	0.201919 (rank : 367)	θ value	5.44631e-05 (rank : 230)
Query Neighborhood Hits	453	Target Neighborhood Hits	1192	Shared Neighborhood Hits	259
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

PGH1_HUMAN
NC score	0.201808 (rank : 368)	θ value	0.125558 (rank : 306)
Query Neighborhood Hits	453	Target Neighborhood Hits	91	Shared Neighborhood Hits	77
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

TIE2_MOUSE
NC score	0.200734 (rank : 369)	θ value	1.43324e-05 (rank : 218)
Query Neighborhood Hits	453	Target Neighborhood Hits	1204	Shared Neighborhood Hits	266
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

NRG2_HUMAN
NC score	0.196462 (rank : 370)	θ value	0.813845 (rank : 354)
Query Neighborhood Hits	453	Target Neighborhood Hits	419	Shared Neighborhood Hits	108
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

VASN_HUMAN
NC score	0.193909 (rank : 371)	θ value	0.000786445 (rank : 244)
Query Neighborhood Hits	453	Target Neighborhood Hits	449	Shared Neighborhood Hits	140
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

LCE3A_HUMAN
NC score	0.193867 (rank : 372)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	453	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

CO8B_MOUSE
NC score	0.191171 (rank : 373)	θ value	0.0961366 (rank : 299)
Query Neighborhood Hits	453	Target Neighborhood Hits	224	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ADAM8_MOUSE
NC score	0.190902 (rank : 374)	θ value	0.00134147 (rank : 249)
Query Neighborhood Hits	453	Target Neighborhood Hits	326	Shared Neighborhood Hits	173
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

PHXR5_MOUSE
NC score	0.189989 (rank : 375)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	71
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

TPA_HUMAN
NC score	0.187811 (rank : 376)	θ value	5.44631e-05 (rank : 231)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	163
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
NC score	0.187710 (rank : 377)	θ value	0.00035302 (rank : 243)
Query Neighborhood Hits	453	Target Neighborhood Hits	335	Shared Neighborhood Hits	169
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

KRA42_HUMAN
NC score	0.186931 (rank : 378)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	453	Target Neighborhood Hits	149	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

APR3_HUMAN
NC score	0.185941 (rank : 379)	θ value	0.47712 (rank : 331)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	49
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

MT3_MOUSE
NC score	0.184846 (rank : 380)	θ value	2.36792 (rank : 394)
Query Neighborhood Hits	453	Target Neighborhood Hits	68	Shared Neighborhood Hits	46
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

CORIN_MOUSE
NC score	0.183383 (rank : 381)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	453	Target Neighborhood Hits	451	Shared Neighborhood Hits	195
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

FSTL3_HUMAN
NC score	0.183033 (rank : 382)	θ value	0.0431538 (rank : 287)
Query Neighborhood Hits	453	Target Neighborhood Hits	162	Shared Neighborhood Hits	89
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

TECTA_HUMAN
NC score	0.182604 (rank : 383)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	453	Target Neighborhood Hits	239	Shared Neighborhood Hits	163
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

MUC2_HUMAN
NC score	0.182594 (rank : 384)	θ value	0.279714 (rank : 320)
Query Neighborhood Hits	453	Target Neighborhood Hits	906	Shared Neighborhood Hits	166
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PCSK6_HUMAN
NC score	0.180973 (rank : 385)	θ value	1.81305 (rank : 385)
Query Neighborhood Hits	453	Target Neighborhood Hits	298	Shared Neighborhood Hits	142
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

EREG_HUMAN
NC score	0.179836 (rank : 386)	θ value	2.36792 (rank : 391)
Query Neighborhood Hits	453	Target Neighborhood Hits	73	Shared Neighborhood Hits	59
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

MT3_HUMAN
NC score	0.179146 (rank : 387)	θ value	1.06291 (rank : 361)
Query Neighborhood Hits	453	Target Neighborhood Hits	82	Shared Neighborhood Hits	54
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

ADA11_HUMAN
NC score	0.178848 (rank : 388)	θ value	0.0113563 (rank : 274)
Query Neighborhood Hits	453	Target Neighborhood Hits	259	Shared Neighborhood Hits	166
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

VASN_MOUSE
NC score	0.177625 (rank : 389)	θ value	0.0148317 (rank : 280)
Query Neighborhood Hits	453	Target Neighborhood Hits	426	Shared Neighborhood Hits	129
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ADA11_MOUSE
NC score	0.177256 (rank : 390)	θ value	0.00869519 (rank : 270)
Query Neighborhood Hits	453	Target Neighborhood Hits	263	Shared Neighborhood Hits	167
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

BMPER_MOUSE
NC score	0.172265 (rank : 391)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	118
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

ADAM8_HUMAN
NC score	0.169663 (rank : 392)	θ value	0.0563607 (rank : 291)
Query Neighborhood Hits	453	Target Neighborhood Hits	327	Shared Neighborhood Hits	181
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADA15_MOUSE
NC score	0.168743 (rank : 393)	θ value	0.0193708 (rank : 281)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	194
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

SHBG_HUMAN
NC score	0.168652 (rank : 394)	θ value	1.06291 (rank : 364)
Query Neighborhood Hits	453	Target Neighborhood Hits	45	Shared Neighborhood Hits	37
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

C1RA_MOUSE
NC score	0.168491 (rank : 395)	θ value	0.21417 (rank : 310)
Query Neighborhood Hits	453	Target Neighborhood Hits	379	Shared Neighborhood Hits	157
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

ADA23_HUMAN
NC score	0.166635 (rank : 396)	θ value	2.36792 (rank : 387)
Query Neighborhood Hits	453	Target Neighborhood Hits	235	Shared Neighborhood Hits	153
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

FSTL3_MOUSE
NC score	0.166429 (rank : 397)	θ value	0.279714 (rank : 317)
Query Neighborhood Hits	453	Target Neighborhood Hits	152	Shared Neighborhood Hits	81
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

C1RB_MOUSE
NC score	0.165749 (rank : 398)	θ value	0.21417 (rank : 311)
Query Neighborhood Hits	453	Target Neighborhood Hits	380	Shared Neighborhood Hits	156
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

SHBG_MOUSE
NC score	0.165584 (rank : 399)	θ value	0.0961366 (rank : 302)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	42
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

LRP3_HUMAN
NC score	0.165065 (rank : 400)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	453	Target Neighborhood Hits	280	Shared Neighborhood Hits	122
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

KR413_HUMAN
NC score	0.164888 (rank : 401)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	453	Target Neighborhood Hits	112	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

MT4_MOUSE
NC score	0.164870 (rank : 402)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	70
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

RECK_MOUSE
NC score	0.164502 (rank : 403)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	453	Target Neighborhood Hits	158	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

ST14_HUMAN
NC score	0.163155 (rank : 404)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	453	Target Neighborhood Hits	409	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
NC score	0.163006 (rank : 405)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	453	Target Neighborhood Hits	419	Shared Neighborhood Hits	184
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ADA23_MOUSE
NC score	0.161813 (rank : 406)	θ value	0.813845 (rank : 350)
Query Neighborhood Hits	453	Target Neighborhood Hits	245	Shared Neighborhood Hits	169
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA19_MOUSE
NC score	0.159489 (rank : 407)	θ value	9.29e-05 (rank : 232)
Query Neighborhood Hits	453	Target Neighborhood Hits	315	Shared Neighborhood Hits	175
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

CO9_MOUSE
NC score	0.159192 (rank : 408)	θ value	0.813845 (rank : 351)
Query Neighborhood Hits	453	Target Neighborhood Hits	153	Shared Neighborhood Hits	91
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

BMPER_HUMAN
NC score	0.157671 (rank : 409)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	453	Target Neighborhood Hits	175	Shared Neighborhood Hits	104
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

TNR25_HUMAN
NC score	0.156762 (rank : 410)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	453	Target Neighborhood Hits	172	Shared Neighborhood Hits	76
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

LCE2C_HUMAN
NC score	0.153838 (rank : 411)	θ value	8.99809 (rank : 450)
Query Neighborhood Hits	453	Target Neighborhood Hits	53	Shared Neighborhood Hits	30
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

ADA19_HUMAN
NC score	0.152835 (rank : 412)	θ value	0.0563607 (rank : 290)
Query Neighborhood Hits	453	Target Neighborhood Hits	381	Shared Neighborhood Hits	164
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

MKS3_MOUSE
NC score	0.152692 (rank : 413)	θ value	0.813845 (rank : 353)
Query Neighborhood Hits	453	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

ASTN_HUMAN
NC score	0.151531 (rank : 414)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	453	Target Neighborhood Hits	105	Shared Neighborhood Hits	78
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
NC score	0.149762 (rank : 415)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	453	Target Neighborhood Hits	98	Shared Neighborhood Hits	75
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

C1R_HUMAN
NC score	0.147957 (rank : 416)	θ value	6.88961 (rank : 426)
Query Neighborhood Hits	453	Target Neighborhood Hits	364	Shared Neighborhood Hits	146
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

CD320_HUMAN
NC score	0.147443 (rank : 417)	θ value	1.81305 (rank : 378)
Query Neighborhood Hits	453	Target Neighborhood Hits	103	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

ESM1_MOUSE
NC score	0.146907 (rank : 418)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	453	Target Neighborhood Hits	107	Shared Neighborhood Hits	66
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ADA15_HUMAN
NC score	0.146855 (rank : 419)	θ value	0.62314 (rank : 337)
Query Neighborhood Hits	453	Target Neighborhood Hits	288	Shared Neighborhood Hits	178
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

MKS3_HUMAN
NC score	0.146290 (rank : 420)	θ value	0.0736092 (rank : 297)
Query Neighborhood Hits	453	Target Neighborhood Hits	79	Shared Neighborhood Hits	69
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

EPGN_MOUSE
NC score	0.145729 (rank : 421)	θ value	0.47712 (rank : 334)
Query Neighborhood Hits	453	Target Neighborhood Hits	63	Shared Neighborhood Hits	52
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

MEP1B_MOUSE
NC score	0.145609 (rank : 422)	θ value	6.88961 (rank : 435)
Query Neighborhood Hits	453	Target Neighborhood Hits	127	Shared Neighborhood Hits	89
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

CO9_HUMAN
NC score	0.145511 (rank : 423)	θ value	1.06291 (rank : 359)
Query Neighborhood Hits	453	Target Neighborhood Hits	147	Shared Neighborhood Hits	88
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

LCE4A_HUMAN
NC score	0.144954 (rank : 424)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	453	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

ADA33_HUMAN
NC score	0.144022 (rank : 425)	θ value	0.00869519 (rank : 271)
Query Neighborhood Hits	453	Target Neighborhood Hits	264	Shared Neighborhood Hits	152
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

CS1A_MOUSE
NC score	0.143727 (rank : 426)	θ value	1.81305 (rank : 381)
Query Neighborhood Hits	453	Target Neighborhood Hits	360	Shared Neighborhood Hits	137
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

ADAM9_MOUSE
NC score	0.143483 (rank : 427)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	453	Target Neighborhood Hits	325	Shared Neighborhood Hits	164
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

CS1B_MOUSE
NC score	0.142540 (rank : 428)	θ value	1.38821 (rank : 371)
Query Neighborhood Hits	453	Target Neighborhood Hits	361	Shared Neighborhood Hits	137
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CO8B_HUMAN
NC score	0.141627 (rank : 429)	θ value	4.03905 (rank : 404)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	86
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

MASP2_HUMAN
NC score	0.141249 (rank : 430)	θ value	0.62314 (rank : 344)
Query Neighborhood Hits	453	Target Neighborhood Hits	364	Shared Neighborhood Hits	144
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

CO8A_HUMAN
NC score	0.139913 (rank : 431)	θ value	2.36792 (rank : 389)
Query Neighborhood Hits	453	Target Neighborhood Hits	200	Shared Neighborhood Hits	95
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

LORI_MOUSE
NC score	0.139788 (rank : 432)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	453	Target Neighborhood Hits	47	Shared Neighborhood Hits	21
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

MASP2_MOUSE
NC score	0.139461 (rank : 433)	θ value	5.27518 (rank : 420)
Query Neighborhood Hits	453	Target Neighborhood Hits	382	Shared Neighborhood Hits	150
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

LCE2A_HUMAN
NC score	0.139236 (rank : 434)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

VEGFC_HUMAN
NC score	0.138825 (rank : 435)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	453	Target Neighborhood Hits	128	Shared Neighborhood Hits	91
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

C1S_HUMAN
NC score	0.138349 (rank : 436)	θ value	1.38821 (rank : 370)
Query Neighborhood Hits	453	Target Neighborhood Hits	359	Shared Neighborhood Hits	143
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

LCE2B_HUMAN
NC score	0.136867 (rank : 437)	θ value	3.0926 (rank : 399)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

KRA24_HUMAN
NC score	0.136866 (rank : 438)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	453	Target Neighborhood Hits	192	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

ADA18_MOUSE
NC score	0.136372 (rank : 439)	θ value	4.03905 (rank : 403)
Query Neighborhood Hits	453	Target Neighborhood Hits	227	Shared Neighborhood Hits	144
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA33_MOUSE
NC score	0.135752 (rank : 440)	θ value	0.62314 (rank : 338)
Query Neighborhood Hits	453	Target Neighborhood Hits	231	Shared Neighborhood Hits	148
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

LRP10_HUMAN
NC score	0.135706 (rank : 441)	θ value	0.125558 (rank : 305)
Query Neighborhood Hits	453	Target Neighborhood Hits	197	Shared Neighborhood Hits	90
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LCE2D_HUMAN
NC score	0.135598 (rank : 442)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	453	Target Neighborhood Hits	50	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

TNR16_HUMAN
NC score	0.135521 (rank : 443)	θ value	6.88961 (rank : 440)
Query Neighborhood Hits	453	Target Neighborhood Hits	183	Shared Neighborhood Hits	89
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

MCSP_MOUSE
NC score	0.135123 (rank : 444)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	453	Target Neighborhood Hits	108	Shared Neighborhood Hits	52
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

ADAM9_HUMAN
NC score	0.134407 (rank : 445)	θ value	0.125558 (rank : 303)
Query Neighborhood Hits	453	Target Neighborhood Hits	243	Shared Neighborhood Hits	151
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

FST_MOUSE
NC score	0.133571 (rank : 446)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	453	Target Neighborhood Hits	146	Shared Neighborhood Hits	72
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

MASP1_HUMAN
NC score	0.133502 (rank : 447)	θ value	3.0926 (rank : 401)
Query Neighborhood Hits	453	Target Neighborhood Hits	369	Shared Neighborhood Hits	144
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

LRP10_MOUSE
NC score	0.133014 (rank : 448)	θ value	5.27518 (rank : 419)
Query Neighborhood Hits	453	Target Neighborhood Hits	169	Shared Neighborhood Hits	88
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

MASP1_MOUSE
NC score	0.131160 (rank : 449)	θ value	4.03905 (rank : 407)
Query Neighborhood Hits	453	Target Neighborhood Hits	364	Shared Neighborhood Hits	145
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

ADAM7_HUMAN
NC score	0.131102 (rank : 450)	θ value	0.47712 (rank : 330)
Query Neighborhood Hits	453	Target Neighborhood Hits	221	Shared Neighborhood Hits	150
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

LRP12_HUMAN
NC score	0.129670 (rank : 451)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	453	Target Neighborhood Hits	205	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

CO8A_MOUSE
NC score	0.129050 (rank : 452)	θ value	5.27518 (rank : 414)
Query Neighborhood Hits	453	Target Neighborhood Hits	182	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

ADAM2_MOUSE
NC score	0.128666 (rank : 453)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	453	Target Neighborhood Hits	209	Shared Neighborhood Hits	131
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

LRP12_MOUSE
NC score	0.128526 (rank : 454)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	453	Target Neighborhood Hits	180	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

WFDC3_HUMAN
NC score	0.127908 (rank : 455)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	453	Target Neighborhood Hits	138	Shared Neighborhood Hits	73
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

GP128_MOUSE
NC score	0.127574 (rank : 456)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	453	Target Neighborhood Hits	141	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

VEGFC_MOUSE
NC score	0.126250 (rank : 457)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	453	Target Neighborhood Hits	119	Shared Neighborhood Hits	86
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ADA30_HUMAN
NC score	0.124597 (rank : 458)	θ value	1.38821 (rank : 367)
Query Neighborhood Hits	453	Target Neighborhood Hits	391	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA22_MOUSE
NC score	0.124428 (rank : 459)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	453	Target Neighborhood Hits	225	Shared Neighborhood Hits	130
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

GP128_HUMAN
NC score	0.124287 (rank : 460)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	453	Target Neighborhood Hits	135	Shared Neighborhood Hits	49
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

EPGN_HUMAN
NC score	0.124194 (rank : 461)	θ value	2.36792 (rank : 390)
Query Neighborhood Hits	453	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

ADA17_HUMAN
NC score	0.124089 (rank : 462)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	453	Target Neighborhood Hits	223	Shared Neighborhood Hits	126
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

TNR16_MOUSE
NC score	0.123881 (rank : 463)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	453	Target Neighborhood Hits	178	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TMPS6_HUMAN
NC score	0.123009 (rank : 464)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	453	Target Neighborhood Hits	338	Shared Neighborhood Hits	137
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

ADA10_HUMAN
NC score	0.122896 (rank : 465)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	453	Target Neighborhood Hits	189	Shared Neighborhood Hits	112
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

CRUM3_HUMAN
NC score	0.122522 (rank : 466)	θ value	3.19293e-05 (rank : 221)
Query Neighborhood Hits	453	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BUF7, Q8N0V8, Q8WVA0	Gene names	CRB3
Domain Architecture	No domain graphic available
Description	Crumbs protein homolog 3 precursor.

ADA12_HUMAN
NC score	0.121311 (rank : 467)	θ value	0.163984 (rank : 307)
Query Neighborhood Hits	453	Target Neighborhood Hits	224	Shared Neighborhood Hits	135
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

FST_HUMAN
NC score	0.121103 (rank : 468)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	453	Target Neighborhood Hits	129	Shared Neighborhood Hits	56
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

ADA21_MOUSE
NC score	0.120025 (rank : 469)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	453	Target Neighborhood Hits	172	Shared Neighborhood Hits	116
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

MT4_HUMAN
NC score	0.119851 (rank : 470)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	453	Target Neighborhood Hits	83	Shared Neighborhood Hits	52
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

ADA28_HUMAN
NC score	0.119501 (rank : 471)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	453	Target Neighborhood Hits	244	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

LCE3B_HUMAN
NC score	0.118614 (rank : 472)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	453	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

ADM1A_MOUSE
NC score	0.118501 (rank : 473)	θ value	5.27518 (rank : 412)
Query Neighborhood Hits	453	Target Neighborhood Hits	230	Shared Neighborhood Hits	151
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

BTC_MOUSE
NC score	0.117517 (rank : 474)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	453	Target Neighborhood Hits	67	Shared Neighborhood Hits	55
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

ADA28_MOUSE
NC score	0.116819 (rank : 475)	θ value	6.88961 (rank : 425)
Query Neighborhood Hits	453	Target Neighborhood Hits	241	Shared Neighborhood Hits	143
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

UROK_HUMAN
NC score	0.116327 (rank : 476)	θ value	0.279714 (rank : 324)
Query Neighborhood Hits	453	Target Neighborhood Hits	272	Shared Neighborhood Hits	115
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

ADA10_MOUSE
NC score	0.115896 (rank : 477)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	453	Target Neighborhood Hits	194	Shared Neighborhood Hits	110
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA22_HUMAN
NC score	0.115632 (rank : 478)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	453	Target Neighborhood Hits	211	Shared Neighborhood Hits	125
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

TMPS6_MOUSE
NC score	0.115336 (rank : 479)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	453	Target Neighborhood Hits	341	Shared Neighborhood Hits	137
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

ADA18_HUMAN
NC score	0.114042 (rank : 480)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	453	Target Neighborhood Hits	184	Shared Neighborhood Hits	125
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

EREG_MOUSE
NC score	0.113853 (rank : 481)	θ value	4.03905 (rank : 405)
Query Neighborhood Hits	453	Target Neighborhood Hits	65	Shared Neighborhood Hits	48
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

GP144_HUMAN
NC score	0.113398 (rank : 482)	θ value	6.88961 (rank : 432)
Query Neighborhood Hits	453	Target Neighborhood Hits	108	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

BAI1_HUMAN
NC score	0.113357 (rank : 483)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	453	Target Neighborhood Hits	375	Shared Neighborhood Hits	54
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

UROK_MOUSE
NC score	0.112181 (rank : 484)	θ value	0.0113563 (rank : 276)
Query Neighborhood Hits	453	Target Neighborhood Hits	273	Shared Neighborhood Hits	120
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

ADA25_MOUSE
NC score	0.111743 (rank : 485)	θ value	1.06291 (rank : 358)
Query Neighborhood Hits	453	Target Neighborhood Hits	213	Shared Neighborhood Hits	133
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA21_HUMAN
NC score	0.110741 (rank : 486)	θ value	0.0736092 (rank : 293)
Query Neighborhood Hits	453	Target Neighborhood Hits	181	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADAM2_HUMAN
NC score	0.110441 (rank : 487)	θ value	2.36792 (rank : 388)
Query Neighborhood Hits	453	Target Neighborhood Hits	175	Shared Neighborhood Hits	108
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

BAI3_MOUSE
NC score	0.110429 (rank : 488)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	453	Target Neighborhood Hits	250	Shared Neighborhood Hits	58
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

ADA32_HUMAN
NC score	0.110346 (rank : 489)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	453	Target Neighborhood Hits	216	Shared Neighborhood Hits	135
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

TNR9_HUMAN
NC score	0.109214 (rank : 490)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	453	Target Neighborhood Hits	166	Shared Neighborhood Hits	69
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

ADA24_MOUSE
NC score	0.108660 (rank : 491)	θ value	5.27518 (rank : 411)
Query Neighborhood Hits	453	Target Neighborhood Hits	230	Shared Neighborhood Hits	145
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

GP133_HUMAN
NC score	0.108580 (rank : 492)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	453	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

BAI3_HUMAN
NC score	0.108154 (rank : 493)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	453	Target Neighborhood Hits	246	Shared Neighborhood Hits	54
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI1_MOUSE
NC score	0.107599 (rank : 494)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	453	Target Neighborhood Hits	340	Shared Neighborhood Hits	50
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

TNR4_MOUSE
NC score	0.106974 (rank : 495)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	453	Target Neighborhood Hits	137	Shared Neighborhood Hits	69
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

CRUM3_MOUSE
NC score	0.106858 (rank : 496)	θ value	5.44631e-05 (rank : 225)
Query Neighborhood Hits	453	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q8QZT4, Q3TJV6	Gene names	Crb3
Domain Architecture	No domain graphic available
Description	Crumbs protein homolog 3 precursor.

GP113_HUMAN
NC score	0.106400 (rank : 497)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

BAI2_MOUSE
NC score	0.104318 (rank : 498)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	453	Target Neighborhood Hits	323	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

TGFA_HUMAN
NC score	0.104280 (rank : 499)	θ value	8.99809 (rank : 452)
Query Neighborhood Hits	453	Target Neighborhood Hits	61	Shared Neighborhood Hits	51
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

ADM1B_MOUSE
NC score	0.104005 (rank : 500)	θ value	0.365318 (rank : 325)
Query Neighborhood Hits	453	Target Neighborhood Hits	236	Shared Neighborhood Hits	120
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

LPHN2_HUMAN
NC score	0.103790 (rank : 501)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	453	Target Neighborhood Hits	136	Shared Neighborhood Hits	18
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

ADA32_MOUSE
NC score	0.103577 (rank : 502)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	453	Target Neighborhood Hits	219	Shared Neighborhood Hits	141
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

GP126_HUMAN
NC score	0.103132 (rank : 503)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	453	Target Neighborhood Hits	187	Shared Neighborhood Hits	39
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

LPHN3_HUMAN
NC score	0.102583 (rank : 504)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	453	Target Neighborhood Hits	139	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

LPHN1_HUMAN
NC score	0.102580 (rank : 505)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	453	Target Neighborhood Hits	155	Shared Neighborhood Hits	16
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

NRG3_MOUSE
NC score	0.102360 (rank : 506)	θ value	0.813845 (rank : 356)
Query Neighborhood Hits	453	Target Neighborhood Hits	132	Shared Neighborhood Hits	70
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

BAI2_HUMAN
NC score	0.102325 (rank : 507)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	453	Target Neighborhood Hits	332	Shared Neighborhood Hits	47
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

ADAM7_MOUSE
NC score	0.101195 (rank : 508)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	453	Target Neighborhood Hits	200	Shared Neighborhood Hits	127
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADA12_MOUSE
NC score	0.100878 (rank : 509)	θ value	1.81305 (rank : 377)
Query Neighborhood Hits	453	Target Neighborhood Hits	474	Shared Neighborhood Hits	113
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

HBEGF_HUMAN
NC score	0.100623 (rank : 510)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	453	Target Neighborhood Hits	61	Shared Neighborhood Hits	49
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

NRG3_HUMAN
NC score	0.100326 (rank : 511)	θ value	0.813845 (rank : 355)
Query Neighborhood Hits	453	Target Neighborhood Hits	119	Shared Neighborhood Hits	64
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

BTC_HUMAN
NC score	0.100271 (rank : 512)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	453	Target Neighborhood Hits	70	Shared Neighborhood Hits	56
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

ADA17_MOUSE
NC score	0.100257 (rank : 513)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	453	Target Neighborhood Hits	201	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

KR124_HUMAN
NC score	0.100029 (rank : 514)	θ value	5.27518 (rank : 418)
Query Neighborhood Hits	453	Target Neighborhood Hits	124	Shared Neighborhood Hits	73
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

GP125_HUMAN
NC score	0.100028 (rank : 515)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	453	Target Neighborhood Hits	327	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

TNR7_HUMAN
NC score	0.099979 (rank : 516)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	453	Target Neighborhood Hits	120	Shared Neighborhood Hits	61
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

SPR2D_MOUSE
NC score	0.099367 (rank : 517)	θ value	5.27518 (rank : 422)
Query Neighborhood Hits	453	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

NRX1B_HUMAN
NC score	0.099176 (rank : 518)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	453	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	P58400	Gene names	NRXN1
Domain Architecture	No domain graphic available
Description	Neurexin-1-beta precursor (Neurexin I-beta).

TNR14_HUMAN
NC score	0.098886 (rank : 519)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	453	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR4_HUMAN
NC score	0.098566 (rank : 520)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	453	Target Neighborhood Hits	152	Shared Neighborhood Hits	62
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

DKK3_MOUSE
NC score	0.098292 (rank : 521)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	453	Target Neighborhood Hits	83	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

GPR64_MOUSE
NC score	0.098095 (rank : 522)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	453	Target Neighborhood Hits	156	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GPR64_HUMAN
NC score	0.097545 (rank : 523)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	453	Target Neighborhood Hits	207	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GP124_MOUSE
NC score	0.097420 (rank : 524)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	453	Target Neighborhood Hits	423	Shared Neighborhood Hits	31
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP112_HUMAN
NC score	0.096949 (rank : 525)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	453	Target Neighborhood Hits	441	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GP114_HUMAN
NC score	0.096900 (rank : 526)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	453	Target Neighborhood Hits	75	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

RSPO3_HUMAN
NC score	0.096539 (rank : 527)	θ value	5.27518 (rank : 421)
Query Neighborhood Hits	453	Target Neighborhood Hits	128	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

GP116_HUMAN
NC score	0.096031 (rank : 528)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	453	Target Neighborhood Hits	167	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP124_HUMAN
NC score	0.095739 (rank : 529)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	453	Target Neighborhood Hits	304	Shared Neighborhood Hits	26
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

CT127_HUMAN
NC score	0.095000 (rank : 530)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	453	Target Neighborhood Hits	67	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

TSG6_MOUSE
NC score	0.094850 (rank : 531)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	453	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSG6_HUMAN
NC score	0.094828 (rank : 532)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	453	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

KR122_HUMAN
NC score	0.094474 (rank : 533)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	453	Target Neighborhood Hits	97	Shared Neighborhood Hits	51
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

GP125_MOUSE
NC score	0.094242 (rank : 534)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	453	Target Neighborhood Hits	329	Shared Neighborhood Hits	27
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

TMG1_HUMAN
NC score	0.093383 (rank : 535)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	453	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

TNR8_MOUSE
NC score	0.093182 (rank : 536)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	453	Target Neighborhood Hits	208	Shared Neighborhood Hits	71
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

GPR56_HUMAN
NC score	0.092237 (rank : 537)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	453	Target Neighborhood Hits	84	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

NRX3B_HUMAN
NC score	0.091611 (rank : 538)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	453	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HDB5	Gene names	NRXN3, KIAA0743
Domain Architecture	No domain graphic available
Description	Neurexin-3-beta precursor (Neurexin III-beta).

FINC_MOUSE
NC score	0.091544 (rank : 539)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	453	Target Neighborhood Hits	309	Shared Neighborhood Hits	58
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

MEP1B_HUMAN
NC score	0.091314 (rank : 540)	θ value	2.36792 (rank : 393)
Query Neighborhood Hits	453	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

ADA29_HUMAN
NC score	0.091274 (rank : 541)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	453	Target Neighborhood Hits	247	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

GPR56_MOUSE
NC score	0.091058 (rank : 542)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	453	Target Neighborhood Hits	89	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

FINC_HUMAN
NC score	0.091019 (rank : 543)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	453	Target Neighborhood Hits	302	Shared Neighborhood Hits	52
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

GNPTA_HUMAN
NC score	0.090480 (rank : 544)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	453	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

LCE5A_HUMAN
NC score	0.090100 (rank : 545)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	453	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

GPR97_MOUSE
NC score	0.089976 (rank : 546)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	453	Target Neighborhood Hits	89	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

GNPTA_MOUSE
NC score	0.089431 (rank : 547)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	453	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

ZNFX1_HUMAN
NC score	0.088646 (rank : 548)	θ value	2.36792 (rank : 397)
Query Neighborhood Hits	453	Target Neighborhood Hits	308	Shared Neighborhood Hits	96
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

PAPPA_MOUSE
NC score	0.088381 (rank : 549)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	453	Target Neighborhood Hits	153	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

ZNFX1_MOUSE
NC score	0.087317 (rank : 550)	θ value	0.365318 (rank : 329)
Query Neighborhood Hits	453	Target Neighborhood Hits	407	Shared Neighborhood Hits	101
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

HPLN2_MOUSE
NC score	0.086981 (rank : 551)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

MT1A_HUMAN
NC score	0.086946 (rank : 552)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	453	Target Neighborhood Hits	74	Shared Neighborhood Hits	42
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1B_HUMAN
NC score	0.086391 (rank : 553)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	453	Target Neighborhood Hits	87	Shared Neighborhood Hits	51
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

SPR2H_MOUSE
NC score	0.086074 (rank : 554)	θ value	4.03905 (rank : 409)
Query Neighborhood Hits	453	Target Neighborhood Hits	82	Shared Neighborhood Hits	22
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

HPLN2_HUMAN
NC score	0.085738 (rank : 555)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	453	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZV7	Gene names	HAPLN2, BRAL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

DKK3_HUMAN
NC score	0.085512 (rank : 556)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	453	Target Neighborhood Hits	74	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

GP115_MOUSE
NC score	0.085509 (rank : 557)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	453	Target Neighborhood Hits	69	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

HPLN3_MOUSE
NC score	0.085472 (rank : 558)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	453	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q80WM5, Q80XX3	Gene names	Hapln3, Lpr3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor (Link protein 3).

PAPPA_HUMAN
NC score	0.085368 (rank : 559)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	453	Target Neighborhood Hits	161	Shared Neighborhood Hits	74
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

GP110_HUMAN
NC score	0.084700 (rank : 560)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	453	Target Neighborhood Hits	87	Shared Neighborhood Hits	23
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

TMG3_HUMAN
NC score	0.084609 (rank : 561)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	453	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD7, Q8N2N6	Gene names	PRRG3, TMG3
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

GP110_MOUSE
NC score	0.084166 (rank : 562)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	453	Target Neighborhood Hits	92	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

HPLN3_HUMAN
NC score	0.083620 (rank : 563)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	453	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	Q96S86	Gene names	HAPLN3
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 3 precursor.

TMG3_MOUSE
NC score	0.083538 (rank : 564)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	453	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PAQ9	Gene names	Prrg3, Gm368, Tmg3
Domain Architecture	No domain graphic available
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

RSPO3_MOUSE
NC score	0.082827 (rank : 565)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	453	Target Neighborhood Hits	120	Shared Neighborhood Hits	59
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

HPLN4_MOUSE
NC score	0.082787 (rank : 566)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	453	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q80WM4, Q80XX2	Gene names	Hapln4, Bral2, Lpr4
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2) (Link protein 4).

CYR61_MOUSE
NC score	0.082736 (rank : 567)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	453	Target Neighborhood Hits	156	Shared Neighborhood Hits	57
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

SPR2G_MOUSE
NC score	0.082631 (rank : 568)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	453	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

GP115_HUMAN
NC score	0.082629 (rank : 569)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	453	Target Neighborhood Hits	87	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

TGFA_MOUSE
NC score	0.082600 (rank : 570)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	453	Target Neighborhood Hits	62	Shared Neighborhood Hits	49
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

GP123_HUMAN
NC score	0.082469 (rank : 571)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	453	Target Neighborhood Hits	120	Shared Neighborhood Hits	20
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

MT1X_HUMAN
NC score	0.082467 (rank : 572)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	453	Target Neighborhood Hits	76	Shared Neighborhood Hits	45
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

CFAI_MOUSE
NC score	0.082245 (rank : 573)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	453	Target Neighborhood Hits	290	Shared Neighborhood Hits	81
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

HPLN1_MOUSE
NC score	0.082193 (rank : 574)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	453	Target Neighborhood Hits	64	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QUP5, Q9D1G9, Q9Z1X7	Gene names	Hapln1, Crtl1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN1_HUMAN
NC score	0.082191 (rank : 575)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	453	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	P10915	Gene names	HAPLN1, CRTL1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 1 precursor (Proteoglycan link protein) (Cartilage link protein) (LP).

HPLN4_HUMAN
NC score	0.082185 (rank : 576)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	453	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	Q86UW8, Q96PW2	Gene names	HAPLN4, BRAL2, KIAA1926
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 4 precursor (Brain link protein 2).

TNR11_HUMAN
NC score	0.081342 (rank : 577)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	453	Target Neighborhood Hits	135	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

CSPG4_MOUSE
NC score	0.081244 (rank : 578)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	453	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

GPR97_HUMAN
NC score	0.080340 (rank : 579)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	453	Target Neighborhood Hits	86	Shared Neighborhood Hits	16
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

TMPS7_HUMAN
NC score	0.079971 (rank : 580)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	453	Target Neighborhood Hits	275	Shared Neighborhood Hits	87
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

CFAI_HUMAN
NC score	0.079494 (rank : 581)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	453	Target Neighborhood Hits	289	Shared Neighborhood Hits	79
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

TMPS7_MOUSE
NC score	0.079432 (rank : 582)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	453	Target Neighborhood Hits	275	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TNR9_MOUSE
NC score	0.079306 (rank : 583)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	453	Target Neighborhood Hits	137	Shared Neighborhood Hits	64
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR23_MOUSE
NC score	0.078981 (rank : 584)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	453	Target Neighborhood Hits	114	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

SPR2F_HUMAN
NC score	0.078908 (rank : 585)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	453	Target Neighborhood Hits	33	Shared Neighborhood Hits	16
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

NRP2_HUMAN
NC score	0.078619 (rank : 586)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	453	Target Neighborhood Hits	120	Shared Neighborhood Hits	40
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

CYR61_HUMAN
NC score	0.078385 (rank : 587)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	453	Target Neighborhood Hits	159	Shared Neighborhood Hits	59
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CSPG4_HUMAN
NC score	0.078021 (rank : 588)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	453	Target Neighborhood Hits	112	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

TNR5_MOUSE
NC score	0.077251 (rank : 589)	θ value	5.27518 (rank : 424)
Query Neighborhood Hits	453	Target Neighborhood Hits	131	Shared Neighborhood Hits	60
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

AD26A_MOUSE
NC score	0.076946 (rank : 590)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	453	Target Neighborhood Hits	165	Shared Neighborhood Hits	102
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

RSPO4_HUMAN
NC score	0.076712 (rank : 591)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	453	Target Neighborhood Hits	110	Shared Neighborhood Hits	60
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

NRP2_MOUSE
NC score	0.076206 (rank : 592)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	453	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

TNR8_HUMAN
NC score	0.076043 (rank : 593)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	453	Target Neighborhood Hits	198	Shared Neighborhood Hits	72
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

ODFP_MOUSE
NC score	0.075849 (rank : 594)	θ value	4.03905 (rank : 408)
Query Neighborhood Hits	453	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PGCA_MOUSE
NC score	0.075525 (rank : 595)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	453	Target Neighborhood Hits	643	Shared Neighborhood Hits	37
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

NEU1_MOUSE
NC score	0.075302 (rank : 596)	θ value	6.88961 (rank : 436)
Query Neighborhood Hits	453	Target Neighborhood Hits	64	Shared Neighborhood Hits	51
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

GPR98_HUMAN
NC score	0.074338 (rank : 597)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	453	Target Neighborhood Hits	202	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

GP111_HUMAN
NC score	0.073990 (rank : 598)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	453	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

NRP1_MOUSE
NC score	0.073537 (rank : 599)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	453	Target Neighborhood Hits	120	Shared Neighborhood Hits	39
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

CDN2B_HUMAN
NC score	0.073343 (rank : 600)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	453	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

DCBD1_HUMAN
NC score	0.073234 (rank : 601)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	453	Target Neighborhood Hits	110	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

CD2A1_MOUSE
NC score	0.073108 (rank : 602)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	453	Target Neighborhood Hits	206	Shared Neighborhood Hits	8
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

NRP1_HUMAN
NC score	0.072983 (rank : 603)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	453	Target Neighborhood Hits	119	Shared Neighborhood Hits	40
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

SPR2B_MOUSE
NC score	0.072888 (rank : 604)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	453	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

CTGF_HUMAN
NC score	0.072760 (rank : 605)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	453	Target Neighborhood Hits	128	Shared Neighborhood Hits	50
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

MFRP_HUMAN
NC score	0.072719 (rank : 606)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	453	Target Neighborhood Hits	165	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

IDD_HUMAN
NC score	0.072293 (rank : 607)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	453	Target Neighborhood Hits	127	Shared Neighborhood Hits	40
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

MT1H_HUMAN
NC score	0.072216 (rank : 608)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	453	Target Neighborhood Hits	78	Shared Neighborhood Hits	44
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

TMG2_HUMAN
NC score	0.071843 (rank : 609)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	453	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	O14669	Gene names	PRRG2, PRGP2, TMG2
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2).

TMG4_HUMAN
NC score	0.071714 (rank : 610)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	453	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD6	Gene names	PRRG4, TMG4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

KR241_HUMAN
NC score	0.071421 (rank : 611)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	453	Target Neighborhood Hits	71	Shared Neighborhood Hits	43
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

DCBD2_HUMAN
NC score	0.071410 (rank : 612)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	453	Target Neighborhood Hits	118	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

CHRD_HUMAN
NC score	0.071316 (rank : 613)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

MT2_MOUSE
NC score	0.071085 (rank : 614)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	453	Target Neighborhood Hits	81	Shared Neighborhood Hits	40
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

TNR22_MOUSE
NC score	0.070820 (rank : 615)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	453	Target Neighborhood Hits	97	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

HBEGF_MOUSE
NC score	0.070767 (rank : 616)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	453	Target Neighborhood Hits	48	Shared Neighborhood Hits	39
SwissProt Accessions	Q06186	Gene names	Hbegf, Dtr, Hegfl
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF).

TMG2_MOUSE
NC score	0.070687 (rank : 617)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	453	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R182, Q9EQI2	Gene names	Prrg2, N4wbp1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2) (NEDD4 WW domain-binding protein 1).

DCBD2_MOUSE
NC score	0.070264 (rank : 618)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	453	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

ENTK_MOUSE
NC score	0.069712 (rank : 619)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	453	Target Neighborhood Hits	338	Shared Neighborhood Hits	86
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

IDD_MOUSE
NC score	0.069700 (rank : 620)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	453	Target Neighborhood Hits	151	Shared Neighborhood Hits	39
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

GP179_HUMAN
NC score	0.069630 (rank : 621)	θ value	0.0736092 (rank : 295)
Query Neighborhood Hits	453	Target Neighborhood Hits	372	Shared Neighborhood Hits	45
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

GPR98_MOUSE
NC score	0.069351 (rank : 622)	θ value	5.27518 (rank : 417)
Query Neighborhood Hits	453	Target Neighborhood Hits	206	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

ADA20_HUMAN
NC score	0.068909 (rank : 623)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	453	Target Neighborhood Hits	143	Shared Neighborhood Hits	77
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

CSMD1_MOUSE
NC score	0.068143 (rank : 624)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	453	Target Neighborhood Hits	193	Shared Neighborhood Hits	71
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_HUMAN
NC score	0.067601 (rank : 625)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	453	Target Neighborhood Hits	176	Shared Neighborhood Hits	62
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

LCE3C_HUMAN
NC score	0.067598 (rank : 626)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	453	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

CAD23_HUMAN
NC score	0.067574 (rank : 627)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	453	Target Neighborhood Hits	197	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CAD23_MOUSE
NC score	0.067391 (rank : 628)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	453	Target Neighborhood Hits	208	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CTGF_MOUSE
NC score	0.066926 (rank : 629)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	453	Target Neighborhood Hits	124	Shared Neighborhood Hits	49
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

CSMD3_HUMAN
NC score	0.066732 (rank : 630)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

PCD15_HUMAN
NC score	0.065977 (rank : 631)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	453	Target Neighborhood Hits	289	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

ANR38_MOUSE
NC score	0.065711 (rank : 632)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	453	Target Neighborhood Hits	512	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

CRDL2_MOUSE
NC score	0.065271 (rank : 633)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	453	Target Neighborhood Hits	81	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CDN2B_MOUSE
NC score	0.065230 (rank : 634)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	453	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

CHRD_MOUSE
NC score	0.065124 (rank : 635)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

PCD16_HUMAN
NC score	0.064880 (rank : 636)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	453	Target Neighborhood Hits	245	Shared Neighborhood Hits	16
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PCD15_MOUSE
NC score	0.064729 (rank : 637)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	453	Target Neighborhood Hits	262	Shared Neighborhood Hits	15
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

ENTK_HUMAN
NC score	0.064375 (rank : 638)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	453	Target Neighborhood Hits	310	Shared Neighborhood Hits	78
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

TMG4_MOUSE
NC score	0.064168 (rank : 639)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	453	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BGN6, Q8BM25	Gene names	Prrg4, Tmg4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

MT1_MOUSE
NC score	0.063995 (rank : 640)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	453	Target Neighborhood Hits	72	Shared Neighborhood Hits	37
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

XLRS1_MOUSE
NC score	0.063783 (rank : 641)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	453	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

KREM1_MOUSE
NC score	0.063610 (rank : 642)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	453	Target Neighborhood Hits	92	Shared Neighborhood Hits	33
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

ANR38_HUMAN
NC score	0.063390 (rank : 643)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	453	Target Neighborhood Hits	443	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

TNR7_MOUSE
NC score	0.063276 (rank : 644)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	453	Target Neighborhood Hits	112	Shared Neighborhood Hits	46
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

PROP_MOUSE
NC score	0.063200 (rank : 645)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	453	Target Neighborhood Hits	165	Shared Neighborhood Hits	43
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

SPR2I_MOUSE
NC score	0.062948 (rank : 646)	θ value	5.27518 (rank : 423)
Query Neighborhood Hits	453	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

RSPO4_MOUSE
NC score	0.062879 (rank : 647)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	453	Target Neighborhood Hits	110	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

ANR15_HUMAN
NC score	0.062641 (rank : 648)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	453	Target Neighborhood Hits	478	Shared Neighborhood Hits	8
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

XLRS1_HUMAN
NC score	0.062488 (rank : 649)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	453	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

LRC21_HUMAN
NC score	0.062422 (rank : 650)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	453	Target Neighborhood Hits	456	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LYPD1_MOUSE
NC score	0.062245 (rank : 651)	θ value	0.0961366 (rank : 301)
Query Neighborhood Hits	453	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BLC3, Q3V2X5, Q3V447, Q9JJ96	Gene names	Lypd1, Lypdc1
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 1 precursor.

ASB16_MOUSE
NC score	0.062012 (rank : 652)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	453	Target Neighborhood Hits	306	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

COCA1_MOUSE
NC score	0.061908 (rank : 653)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	453	Target Neighborhood Hits	467	Shared Neighborhood Hits	36
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

MFRP_MOUSE
NC score	0.061834 (rank : 654)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	453	Target Neighborhood Hits	166	Shared Neighborhood Hits	51
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

KREM2_HUMAN
NC score	0.061562 (rank : 655)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	453	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

PCDLK_HUMAN
NC score	0.061399 (rank : 656)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	453	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYE9, Q9NXP8	Gene names	PCLKC
Domain Architecture	No domain graphic available
Description	Protocadherin LKC precursor (PC-LKC).

NETO1_HUMAN
NC score	0.061119 (rank : 657)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	453	Target Neighborhood Hits	110	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

TNR11_MOUSE
NC score	0.061028 (rank : 658)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	453	Target Neighborhood Hits	121	Shared Neighborhood Hits	53
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

ECM2_HUMAN
NC score	0.060964 (rank : 659)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	453	Target Neighborhood Hits	402	Shared Neighborhood Hits	34
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

LRC21_MOUSE
NC score	0.060951 (rank : 660)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	453	Target Neighborhood Hits	462	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

CFAB_MOUSE
NC score	0.060678 (rank : 661)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	453	Target Neighborhood Hits	262	Shared Neighborhood Hits	55
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

NETO1_MOUSE
NC score	0.060648 (rank : 662)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	453	Target Neighborhood Hits	109	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

KREM1_HUMAN
NC score	0.060565 (rank : 663)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	453	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

CRDL2_HUMAN
NC score	0.060509 (rank : 664)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	453	Target Neighborhood Hits	99	Shared Neighborhood Hits	40
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

GPIX_HUMAN
NC score	0.060478 (rank : 665)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	453	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	P14770, Q14445, Q92525	Gene names	GP9
Domain Architecture
Description	Platelet glycoprotein IX precursor (GPIX) (CD42a antigen).

CSMD2_HUMAN
NC score	0.060296 (rank : 666)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	453	Target Neighborhood Hits	188	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

SHAN1_HUMAN
NC score	0.060294 (rank : 667)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	453	Target Neighborhood Hits	1041	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TNR26_MOUSE
NC score	0.060117 (rank : 668)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	453	Target Neighborhood Hits	106	Shared Neighborhood Hits	55
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR6_MOUSE
NC score	0.060002 (rank : 669)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	453	Target Neighborhood Hits	99	Shared Neighborhood Hits	43
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

COCA1_HUMAN
NC score	0.059731 (rank : 670)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	453	Target Neighborhood Hits	458	Shared Neighborhood Hits	35
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COKA1_HUMAN
NC score	0.059504 (rank : 671)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	453	Target Neighborhood Hits	403	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

KREM2_MOUSE
NC score	0.059436 (rank : 672)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	453	Target Neighborhood Hits	90	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

HYAL3_MOUSE
NC score	0.059329 (rank : 673)	θ value	0.365318 (rank : 326)
Query Neighborhood Hits	453	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VEI3, Q8VBX7, Q8VI77	Gene names	Hyal3, Hyl3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3).

IKBE_HUMAN
NC score	0.059001 (rank : 674)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	453	Target Neighborhood Hits	288	Shared Neighborhood Hits	8
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

TNR3_MOUSE
NC score	0.058556 (rank : 675)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	453	Target Neighborhood Hits	113	Shared Neighborhood Hits	51
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

BCL3_HUMAN
NC score	0.058546 (rank : 676)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	453	Target Neighborhood Hits	324	Shared Neighborhood Hits	8
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

LYPD1_HUMAN
NC score	0.058007 (rank : 677)	θ value	0.62314 (rank : 343)
Query Neighborhood Hits	453	Target Neighborhood Hits	24	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N2G4, Q96AC2	Gene names	LYPD1, LYPDC1
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 1 precursor.

LRC17_MOUSE
NC score	0.057992 (rank : 678)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	453	Target Neighborhood Hits	268	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CXD9	Gene names	Lrrc17
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 17 precursor.

PKD1_HUMAN
NC score	0.057988 (rank : 679)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	453	Target Neighborhood Hits	387	Shared Neighborhood Hits	29
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

THRB_HUMAN
NC score	0.057802 (rank : 680)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	453	Target Neighborhood Hits	196	Shared Neighborhood Hits	33
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

PSD10_HUMAN
NC score	0.057613 (rank : 681)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	453	Target Neighborhood Hits	301	Shared Neighborhood Hits	8
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

MT1E_HUMAN
NC score	0.057435 (rank : 682)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	453	Target Neighborhood Hits	75	Shared Neighborhood Hits	44
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

IKBA_HUMAN
NC score	0.057400 (rank : 683)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	453	Target Neighborhood Hits	280	Shared Neighborhood Hits	8
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ANR40_HUMAN
NC score	0.057357 (rank : 684)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	453	Target Neighborhood Hits	224	Shared Neighborhood Hits	8
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

LRC17_HUMAN
NC score	0.057244 (rank : 685)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	453	Target Neighborhood Hits	267	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N6Y2, Q13288, Q6UWA7, Q75MG5	Gene names	LRRC17, P37NB
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 17 precursor (p37NB).

NETO2_MOUSE
NC score	0.057155 (rank : 686)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	453	Target Neighborhood Hits	113	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

HYAL3_HUMAN
NC score	0.057138 (rank : 687)	θ value	1.81305 (rank : 384)
Query Neighborhood Hits	453	Target Neighborhood Hits	45	Shared Neighborhood Hits	37
SwissProt Accessions	O43820, O60540, Q8NFK2, Q8NFK3, Q8NFK4, Q96E56, Q9BRW9	Gene names	HYAL3, LUCA3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3) (LUCA-3).

NETO2_HUMAN
NC score	0.057015 (rank : 688)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	453	Target Neighborhood Hits	109	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

COEA1_MOUSE
NC score	0.056758 (rank : 689)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	453	Target Neighborhood Hits	402	Shared Neighborhood Hits	29
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

WISP2_HUMAN
NC score	0.056731 (rank : 690)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	453	Target Neighborhood Hits	126	Shared Neighborhood Hits	35
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

FA5_HUMAN
NC score	0.056490 (rank : 691)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	453	Target Neighborhood Hits	172	Shared Neighborhood Hits	16
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

PA2G6_HUMAN
NC score	0.056446 (rank : 692)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	453	Target Neighborhood Hits	284	Shared Neighborhood Hits	8
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PSD10_MOUSE
NC score	0.056339 (rank : 693)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	453	Target Neighborhood Hits	293	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

LRC24_HUMAN
NC score	0.056301 (rank : 694)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	453	Target Neighborhood Hits	404	Shared Neighborhood Hits	16
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

THRB_MOUSE
NC score	0.056301 (rank : 695)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	453	Target Neighborhood Hits	195	Shared Neighborhood Hits	33
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

PA2G6_MOUSE
NC score	0.056250 (rank : 696)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	453	Target Neighborhood Hits	293	Shared Neighborhood Hits	8
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ASB8_HUMAN
NC score	0.056239 (rank : 697)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	453	Target Neighborhood Hits	294	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANR47_MOUSE
NC score	0.056214 (rank : 698)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	453	Target Neighborhood Hits	350	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANR47_HUMAN
NC score	0.056017 (rank : 699)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	453	Target Neighborhood Hits	369	Shared Neighborhood Hits	8
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

PAP2_HUMAN
NC score	0.055843 (rank : 700)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	453	Target Neighborhood Hits	106	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

XLKD1_MOUSE
NC score	0.055698 (rank : 701)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	453	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BHC0, Q3TUC1, Q99NE4	Gene names	Xlkd1, Crsbp1
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Extracellular link domain-containing protein 1).

BCL3_MOUSE
NC score	0.055663 (rank : 702)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	453	Target Neighborhood Hits	388	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ASB8_MOUSE
NC score	0.055645 (rank : 703)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	453	Target Neighborhood Hits	293	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

CAD17_MOUSE
NC score	0.055633 (rank : 704)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	453	Target Neighborhood Hits	157	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R100	Gene names	Cdh17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (BILL- cadherin) (P130).

KR111_HUMAN
NC score	0.055492 (rank : 705)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	453	Target Neighborhood Hits	90	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

ANR23_HUMAN
NC score	0.055450 (rank : 706)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	453	Target Neighborhood Hits	291	Shared Neighborhood Hits	8
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

GP1BB_HUMAN
NC score	0.055356 (rank : 707)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	453	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	P13224, Q8NG40	Gene names	GP1BB
Domain Architecture
Description	Platelet glycoprotein Ib beta chain precursor (GP-Ib beta) (GPIbB) (GPIb-beta) (Antigen CD42b-beta) (CD42c antigen).

LRC24_MOUSE
NC score	0.055061 (rank : 708)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	453	Target Neighborhood Hits	387	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

IKBA_MOUSE
NC score	0.054965 (rank : 709)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	453	Target Neighborhood Hits	283	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

XLKD1_HUMAN
NC score	0.054678 (rank : 710)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	453	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y5Y7, Q8TC18, Q9UNF4	Gene names	XLKD1, CRSBP1, HAR
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Hyaluronic acid receptor) (Extracellular link domain-containing protein 1).

GABP3_MOUSE
NC score	0.054471 (rank : 711)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	453	Target Neighborhood Hits	330	Shared Neighborhood Hits	9
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

COEA1_HUMAN
NC score	0.054294 (rank : 712)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	453	Target Neighborhood Hits	427	Shared Neighborhood Hits	30
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

ANKR6_HUMAN
NC score	0.054205 (rank : 713)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	453	Target Neighborhood Hits	439	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

CFAB_HUMAN
NC score	0.054165 (rank : 714)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	453	Target Neighborhood Hits	251	Shared Neighborhood Hits	50
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

ANR25_HUMAN
NC score	0.054159 (rank : 715)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	453	Target Neighborhood Hits	350	Shared Neighborhood Hits	11
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

HECD1_HUMAN
NC score	0.054121 (rank : 716)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	453	Target Neighborhood Hits	371	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

CAD17_HUMAN
NC score	0.053715 (rank : 717)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	453	Target Neighborhood Hits	154	Shared Neighborhood Hits	8
SwissProt Accessions	Q12864, Q15336	Gene names	CDH17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (Intestinal peptide-associated transporter HPT-1).

GP1BB_MOUSE
NC score	0.053506 (rank : 718)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	453	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	P56400	Gene names	Gp1bb
Domain Architecture
Description	Platelet glycoprotein Ib beta chain precursor (GP-Ib beta) (GPIbB) (GPIb-beta) (CD42c antigen).

PCDH1_HUMAN
NC score	0.053504 (rank : 719)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	453	Target Neighborhood Hits	174	Shared Neighborhood Hits	10
SwissProt Accessions	Q08174	Gene names	PCDH1
Domain Architecture
Description	Protocadherin-1 precursor (Protocadherin-42) (PC42) (Cadherin-like protein 1).

RSPO2_MOUSE
NC score	0.053041 (rank : 720)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	453	Target Neighborhood Hits	88	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

GABP2_HUMAN
NC score	0.053003 (rank : 721)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	453	Target Neighborhood Hits	454	Shared Neighborhood Hits	8
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

TMPS9_HUMAN
NC score	0.052989 (rank : 722)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

AN36B_HUMAN
NC score	0.052974 (rank : 723)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	453	Target Neighborhood Hits	294	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANR49_HUMAN
NC score	0.052958 (rank : 724)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	453	Target Neighborhood Hits	282	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

TMPS9_MOUSE
NC score	0.052764 (rank : 725)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	453	Target Neighborhood Hits	296	Shared Neighborhood Hits	68
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TNR5_HUMAN
NC score	0.052761 (rank : 726)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	453	Target Neighborhood Hits	102	Shared Neighborhood Hits	48
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

ANR40_MOUSE
NC score	0.052710 (rank : 727)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	453	Target Neighborhood Hits	228	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ASZ1_MOUSE
NC score	0.052677 (rank : 728)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	453	Target Neighborhood Hits	319	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

PCDH7_HUMAN
NC score	0.052661 (rank : 729)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	453	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

LRC52_HUMAN
NC score	0.052611 (rank : 730)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	453	Target Neighborhood Hits	229	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N7C0, Q5T9K5	Gene names	LRRC52
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 52 precursor.

GABP2_MOUSE
NC score	0.052595 (rank : 731)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	453	Target Neighborhood Hits	429	Shared Neighborhood Hits	8
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

SPIT1_HUMAN
NC score	0.052365 (rank : 732)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	453	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

IKBE_MOUSE
NC score	0.052359 (rank : 733)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	453	Target Neighborhood Hits	308	Shared Neighborhood Hits	10
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

LRC55_MOUSE
NC score	0.052339 (rank : 734)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	453	Target Neighborhood Hits	254	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UY51	Gene names	Lrrc55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

NRX2B_HUMAN
NC score	0.052231 (rank : 735)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	453	Target Neighborhood Hits	481	Shared Neighborhood Hits	28
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

TNR19_MOUSE
NC score	0.052080 (rank : 736)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	453	Target Neighborhood Hits	100	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

PCDH9_HUMAN
NC score	0.052031 (rank : 737)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	453	Target Neighborhood Hits	180	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HC56	Gene names	PCDH9
Domain Architecture
Description	Protocadherin-9 precursor.

CALCR_HUMAN
NC score	0.052009 (rank : 738)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	453	Target Neighborhood Hits	67	Shared Neighborhood Hits	16
SwissProt Accessions	P30988, O14585, Q13941, Q6DJU8, Q6T712	Gene names	CALCR
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

PCD20_MOUSE
NC score	0.051987 (rank : 739)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	453	Target Neighborhood Hits	150	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BIZ0, Q8BIV2	Gene names	Pcdh20
Domain Architecture	No domain graphic available
Description	Protocadherin-20 precursor.

CAD16_HUMAN
NC score	0.051961 (rank : 740)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	453	Target Neighborhood Hits	159	Shared Neighborhood Hits	9
SwissProt Accessions	O75309, Q6UW93	Gene names	CDH16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

PCD20_HUMAN
NC score	0.051921 (rank : 741)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	453	Target Neighborhood Hits	153	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N6Y1, Q8NDN4, Q9NRT9	Gene names	PCDH20
Domain Architecture	No domain graphic available
Description	Protocadherin-20 precursor (Protocadherin-13).

ASB14_MOUSE
NC score	0.051694 (rank : 742)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	453	Target Neighborhood Hits	293	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

CAD16_MOUSE
NC score	0.051589 (rank : 743)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	453	Target Neighborhood Hits	170	Shared Neighborhood Hits	10
SwissProt Accessions	O88338, Q9JLZ5	Gene names	Cdh16
Domain Architecture
Description	Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).

ANR50_HUMAN
NC score	0.051518 (rank : 744)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	453	Target Neighborhood Hits	361	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

LRC55_HUMAN
NC score	0.051397 (rank : 745)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	453	Target Neighborhood Hits	257	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZSA7	Gene names	LRRC55
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 55.

CDN2D_MOUSE
NC score	0.051389 (rank : 746)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	453	Target Neighborhood Hits	267	Shared Neighborhood Hits	8
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

MT1L_HUMAN
NC score	0.051212 (rank : 747)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	453	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

AMGO3_HUMAN
NC score	0.051199 (rank : 748)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	453	Target Neighborhood Hits	276	Shared Neighborhood Hits	11
SwissProt Accessions	Q86WK7, Q96JH6	Gene names	AMIGO3, ALI3, KIAA1851
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 3 precursor (AMIGO-3) (Alivin-3).

CT075_MOUSE
NC score	0.051188 (rank : 749)	θ value	6.88961 (rank : 428)
Query Neighborhood Hits	453	Target Neighborhood Hits	358	Shared Neighborhood Hits	23
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

ANR33_MOUSE
NC score	0.051097 (rank : 750)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	453	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

EHMT2_HUMAN
NC score	0.051082 (rank : 751)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	453	Target Neighborhood Hits	498	Shared Neighborhood Hits	20
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

NOV_HUMAN
NC score	0.051034 (rank : 752)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	453	Target Neighborhood Hits	128	Shared Neighborhood Hits	48
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

PC11X_HUMAN
NC score	0.051009 (rank : 753)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	453	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BZA7, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5	Gene names	PCDH11X, PCDH11, PCDHX
Domain Architecture	No domain graphic available
Description	Protocadherin-11 X-linked precursor (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S).

PC11Y_HUMAN
NC score	0.050961 (rank : 754)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	453	Target Neighborhood Hits	205	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BZA8, Q70LR6, Q70LR8, Q70LS0, Q70LS1, Q70LS2, Q70LS3, Q70LS4, Q70LS5, Q8WY34, Q9BZA9, Q9H4E1	Gene names	PCDH11Y, PCDH11, PCDH22, PCDHY
Domain Architecture	No domain graphic available
Description	Protocadherin-11 Y-linked precursor (Protocadherin-11) (Protocadherin- 22) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC).

CD2A1_HUMAN
NC score	0.050945 (rank : 755)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	453	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

ANR29_HUMAN
NC score	0.050833 (rank : 756)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	453	Target Neighborhood Hits	294	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

CALCR_MOUSE
NC score	0.050747 (rank : 757)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	453	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	Q60755	Gene names	Calcr
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

CLPB_MOUSE
NC score	0.050719 (rank : 758)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	453	Target Neighborhood Hits	289	Shared Neighborhood Hits	10
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

RSPO2_HUMAN
NC score	0.050662 (rank : 759)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	453	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RN5A_HUMAN
NC score	0.050518 (rank : 760)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	453	Target Neighborhood Hits	608	Shared Neighborhood Hits	11
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

PROP_HUMAN
NC score	0.050487 (rank : 761)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	453	Target Neighborhood Hits	126	Shared Neighborhood Hits	33
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

ANR49_MOUSE
NC score	0.050393 (rank : 762)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	453	Target Neighborhood Hits	285	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANR23_MOUSE
NC score	0.050374 (rank : 763)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	453	Target Neighborhood Hits	296	Shared Neighborhood Hits	8
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANR41_HUMAN
NC score	0.050330 (rank : 764)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	453	Target Neighborhood Hits	332	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

LRC3B_HUMAN
NC score	0.050291 (rank : 765)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	453	Target Neighborhood Hits	215	Shared Neighborhood Hits	9
SwissProt Accessions	Q96PB8	Gene names	LRRC3B, LRP15
Domain Architecture
Description	Leucine-rich repeat-containing protein 3B precursor (Leucine-rich repeat protein LRP15).

LRC3B_MOUSE
NC score	0.050283 (rank : 766)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	453	Target Neighborhood Hits	215	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VCH9	Gene names	Lrrc3b, Lrp15
Domain Architecture
Description	Leucine-rich repeat-containing protein 3B precursor (Leucine-rich repeat protein LRP15).

ASZ1_HUMAN
NC score	0.050246 (rank : 767)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	453	Target Neighborhood Hits	341	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

TNR6B_HUMAN
NC score	0.050234 (rank : 768)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	453	Target Neighborhood Hits	103	Shared Neighborhood Hits	41
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

ANFY1_HUMAN
NC score	0.050226 (rank : 769)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	453	Target Neighborhood Hits	480	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_MOUSE
NC score	0.050173 (rank : 770)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	453	Target Neighborhood Hits	480	Shared Neighborhood Hits	9
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

SPR2E_HUMAN
NC score	0.050156 (rank : 771)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	453	Target Neighborhood Hits	32	Shared Neighborhood Hits	15
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

PP16A_MOUSE
NC score	0.050029 (rank : 772)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	453	Target Neighborhood Hits	318	Shared Neighborhood Hits	9
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

EPHB4_HUMAN
NC score	0.044607 (rank : 773)	θ value	1.81305 (rank : 383)
Query Neighborhood Hits	453	Target Neighborhood Hits	1056	Shared Neighborhood Hits	132
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

SPY4_MOUSE
NC score	0.039316 (rank : 774)	θ value	6.88961 (rank : 439)
Query Neighborhood Hits	453	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WTP2, Q9QXV7	Gene names	Spry4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

INSRR_HUMAN
NC score	0.034050 (rank : 775)	θ value	8.99809 (rank : 447)
Query Neighborhood Hits	453	Target Neighborhood Hits	950	Shared Neighborhood Hits	103
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

HYAL2_HUMAN
NC score	0.027142 (rank : 776)	θ value	8.99809 (rank : 446)
Query Neighborhood Hits	453	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q12891, O15177, Q9BW29	Gene names	HYAL2, LUCA2
Domain Architecture
Description	Hyaluronidase-2 precursor (EC 3.2.1.35) (Hyal-2) (Hyaluronoglucosaminidase-2) (LUCA-2).

MMRN2_HUMAN
NC score	0.026509 (rank : 777)	θ value	1.38821 (rank : 373)
Query Neighborhood Hits	453	Target Neighborhood Hits	400	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

TNR12_HUMAN
NC score	0.025468 (rank : 778)	θ value	0.163984 (rank : 309)
Query Neighborhood Hits	453	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NP84, Q9HCS0	Gene names	TNFRSF12A, FN14
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 12A precursor (Fibroblast growth factor-inducible immediate-early response protein 14) (FGF-inducible 14) (Tweak-receptor) (TweakR) (CD266 antigen).

EPHB6_HUMAN
NC score	0.024602 (rank : 779)	θ value	0.0736092 (rank : 294)
Query Neighborhood Hits	453	Target Neighborhood Hits	912	Shared Neighborhood Hits	81
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

EPHA1_HUMAN
NC score	0.023453 (rank : 780)	θ value	5.27518 (rank : 415)
Query Neighborhood Hits	453	Target Neighborhood Hits	997	Shared Neighborhood Hits	96
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

F19A2_MOUSE
NC score	0.022325 (rank : 781)	θ value	8.99809 (rank : 445)
Query Neighborhood Hits	453	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TPG7, Q5M9Q3	Gene names	Fam19a2, Tafa2
Domain Architecture	No domain graphic available
Description	Protein FAM19A2 precursor (Chemokine-like protein TAFA-2).

F19A2_HUMAN
NC score	0.022272 (rank : 782)	θ value	8.99809 (rank : 444)
Query Neighborhood Hits	453	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N3H0, Q4G0R9, Q68DK0, Q6GTX6	Gene names	FAM19A2, TAFA2
Domain Architecture	No domain graphic available
Description	Protein FAM19A2 precursor (Chemokine-like protein TAFA-2).

F19A1_MOUSE
NC score	0.021021 (rank : 783)	θ value	8.99809 (rank : 443)
Query Neighborhood Hits	453	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TPG8	Gene names	Fam19a1, Tafa1
Domain Architecture	No domain graphic available
Description	Protein FAM19A1 precursor (Chemokine-like protein TAFA-1).

F19A1_HUMAN
NC score	0.020999 (rank : 784)	θ value	8.99809 (rank : 442)
Query Neighborhood Hits	453	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z5A9, Q8TCL8	Gene names	FAM19A1, TAFA1
Domain Architecture	No domain graphic available
Description	Protein FAM19A1 precursor (Chemokine-like protein TAFA-1).

IGF1R_MOUSE
NC score	0.019969 (rank : 785)	θ value	0.813845 (rank : 352)
Query Neighborhood Hits	453	Target Neighborhood Hits	973	Shared Neighborhood Hits	103
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

EPHB6_MOUSE
NC score	0.017474 (rank : 786)	θ value	0.21417 (rank : 312)
Query Neighborhood Hits	453	Target Neighborhood Hits	906	Shared Neighborhood Hits	59
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

IGF1R_HUMAN
NC score	0.015224 (rank : 787)	θ value	0.21417 (rank : 313)
Query Neighborhood Hits	453	Target Neighborhood Hits	977	Shared Neighborhood Hits	96
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

F19A3_HUMAN
NC score	0.015177 (rank : 788)	θ value	4.03905 (rank : 406)
Query Neighborhood Hits	453	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z5A8, Q7Z5A6	Gene names	FAM19A3, TAFA3
Domain Architecture	No domain graphic available
Description	Protein FAM19A3 precursor (Chemokine-like protein TAFA-3).

GFRA3_HUMAN
NC score	0.014129 (rank : 789)	θ value	6.88961 (rank : 431)
Query Neighborhood Hits	453	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	O60609, Q6UW20, Q8IUZ2	Gene names	GFRA3
Domain Architecture
Description	GDNF family receptor alpha-3 precursor (GFR-alpha-3).

ERBB3_MOUSE
NC score	0.013255 (rank : 790)	θ value	6.88961 (rank : 429)
Query Neighborhood Hits	453	Target Neighborhood Hits	898	Shared Neighborhood Hits	73
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

CEP68_MOUSE
NC score	0.008335 (rank : 791)	θ value	1.81305 (rank : 379)
Query Neighborhood Hits	453	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0D9, Q3US49, Q5SW85, Q8R2V0	Gene names	Cep68
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

BACH2_HUMAN
NC score	0.004453 (rank : 792)	θ value	5.27518 (rank : 413)
Query Neighborhood Hits	453	Target Neighborhood Hits	234	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYV9, Q59H70, Q5T793, Q9NTS5	Gene names	BACH2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

SC6A5_MOUSE
NC score	0.002053 (rank : 793)	θ value	0.279714 (rank : 322)
Query Neighborhood Hits	453	Target Neighborhood Hits	135	Shared Neighborhood Hits	6
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

LIMD1_MOUSE
NC score	0.001067 (rank : 794)	θ value	3.0926 (rank : 400)
Query Neighborhood Hits	453	Target Neighborhood Hits	291	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

AAA1_MOUSE
NC score	0.000749 (rank : 795)	θ value	5.27518 (rank : 410)
Query Neighborhood Hits	453	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P63115, Q9CW25, Q9JMH8	Gene names	Slc7a10, Asc1
Domain Architecture	No domain graphic available
Description	Asc-type amino acid transporter 1 (Asc-1) (D-serine transporter).

TP53B_MOUSE
NC score	-0.000230 (rank : 796)	θ value	8.99809 (rank : 453)
Query Neighborhood Hits	453	Target Neighborhood Hits	644	Shared Neighborhood Hits	15
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

FOXO4_HUMAN
NC score	-0.000559 (rank : 797)	θ value	5.27518 (rank : 416)
Query Neighborhood Hits	453	Target Neighborhood Hits	197	Shared Neighborhood Hits	6
SwissProt Accessions	P98177, O43821, Q13720, Q3KPF1, Q8TDK9	Gene names	MLLT7, AFX, AFX1, FOXO4
Domain Architecture
Description	Fork head domain transcription factor AFX1 (Forkhead box protein O4).

DPF1_HUMAN
NC score	-0.001755 (rank : 798)	θ value	8.99809 (rank : 441)
Query Neighborhood Hits	453	Target Neighborhood Hits	136	Shared Neighborhood Hits	2
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

TITF1_HUMAN
NC score	-0.006024 (rank : 799)	θ value	2.36792 (rank : 396)
Query Neighborhood Hits	453	Target Neighborhood Hits	332	Shared Neighborhood Hits	2
SwissProt Accessions	P43699, O14954, O14955, Q9BRJ8	Gene names	TITF1, NKX2-1, NKX2A, TTF1
Domain Architecture
Description	Thyroid transcription factor 1 (Thyroid nuclear factor 1) (TTF-1) (Homeobox protein Nkx-2.1) (Homeobox protein NK-2 homolog A).